American Chemical Suppliers

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Product
p-Phenylenedipropionic acid p-Phenylenedipropionic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-PHENYLENEDIPROPIONIC ACID;P-PHENYLENEDIPROPIONIC ACID;3,3-(p-phenylene)dipropionic acid;p-Benzenedipropionic acid.;p-Phenylenedipropionic acid, HPLC 98%;1,4-Benzenedipropionic acid;3,3-(1,4-Phenylene)bis(propionic acid);3,3-(1,4-Phenylene)bispropanoic. Product Category: Polymer/Macromolecule. Appearance: off-white to light yellow powder. CAS No. 4251-21-2. Molecular formula: C12H14O4. Mole weight: 222.24. Purity: 0.98. IUPACName: 3-[4-(2-carboxyethyl)phenyl]propanoic acid. Canonical SMILES: C1=CC(=CC=C1CCC(=O)O)CCC(=O)O. Density: 1.253g/cm³. ECNumber: 224-215-6. Product ID: ACM4251212. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
p-Phenyloxyphenylacetic Acid p-Phenyloxyphenylacetic Acid is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4- (4-phenoxyphenyl ethyl amino) quinazoline. Group: Biochemicals. Alternative Names: 4-Phenoxybenzeneacetic Acid; (4-Phenoxyphenyl)acetic Acid; 2-(4-Phenoxyphenyl)acetic Acid; 4- (Carboxymethyl) diphenyl Ether; 4-Phenoxyphenylethanoic Acid; NSC 43857; p-Phenyloxyphenylacetic Acid. Grades: Highly Purified. CAS No. 6328-74-1. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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p-(phenylthio)benzyl alcohol p-(phenylthio)benzyl alcohol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(Phenylthio)Benzyl Chloride. Appearance: Pale Beige to Light Beige Solid. CAS No. 6317-56-2. Molecular formula: C13H12OS. Mole weight: 216.29. Purity: 0.98. Product ID: ACM6317562. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PPHT hydrochloride PPHT hydrochloride is a potent and selective dopamine D2 agonist. Uses: Dopamine agonists. Synonyms: (+/-)-PPHT hydrochloride; 6-[2-phenylethyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: 98%. CAS No. 71787-90-1. Molecular formula: C21H27NO.HCl. Mole weight: 345.91. BOC Sciences 10
PPI-2458 PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 ( MetAP-2 ). PPI-2458 can be used for arthritis and lymphoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 431077-35-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13731. MedChemExpress MCE
PPI-2458 PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class. Synonyms: PPI 2458; PPI2458; Metapro; NSC-720735. CAS No. 431077-35-9. Molecular formula: C22H36N2O6. Mole weight: 424.54. BOC Sciences 11
PPIase-Parvulin Inhibitor PPIase-Parvulin Inhibitor is a cell-permeable inhibitor of the PPIases Pin1 and Pin4 (IC50s = 1.5 and 1.0 μM, respectively). It blocks the proliferation of cancer cells that overexpress Pin1 and Pin4 (IC50 = 2-5 μM). Synonyms: HIC 016C; PiB; Diethyl-1, 3, 6, 8-tetrahydro-1, 3, 6, 8-tetraoxobenzo[lmn][3, 8]phenanthroline-2, 7-diacetate. Grades: ≥95%. CAS No. 64005-90-9. Molecular formula: C22H18N2O8. Mole weight: 438.4. BOC Sciences 9
PPI Inhibitor Library A unique collection of 260 PPI-related compounds for drug screening; - Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc. - Detailed compound information with structure, target, and biological activity description; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9400. Categories: PPI Inhibitor Libraries. TARGETMOL CHEMICALS
PPIP PPIP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4'-Bis(1-phenyl-1H-phenanthro[9,10-d]imidazol-2-yl)biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1147081-46-6. Molecular formula: C54H34N4. Mole weight: 738.87. Product ID: ACM1147081466. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PPM-18 PPM-18 is a synthetic naphthoquinone compound and an anti-inflammatory agent. It potently inhibits the expression of inducible nitric oxide synthase (iNOS) via suppressing NF-κB activation in vitro and in vivo (IC50 = 5 μM). Synonyms: NSC 73233; n-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzamide; NQN-1; 2-Benzoylamino-1,4-naphthoquinone. Grades: ≥95%. CAS No. 65240-86-0. Molecular formula: C17H11NO3. Mole weight: 277.3. BOC Sciences 10
PPM1A-IN-1 PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2919466-30-9. Pack Sizes: 1 mg. Product ID: HY-164220. MedChemExpress MCE
PPNDS PPNDS. Group: Biochemicals. Grades: Purified. CAS No. 1021868-77-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PPNDS PPNDS is a potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). PNDS is approximately 50-fold less selective for P2Y1R and does not interact with α1A-adrenergic, adenosine A1 and A2B, histamine H1, or muscarinic M3 receptors. Synonyms: Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt. CAS No. 1021868-77-8. Molecular formula: C18H11N4Na4O14PS2. Mole weight: 694.36. BOC Sciences 9
PPNDS tetrasodium PPNDS tetrasodium is a selective and competitive meprin β inhibitor ( IC 50 : 80 nM, K i : 8 nM), and also inhibits ADAM10 ( IC 50 : 1.2 μM). PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium. PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021868-77-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108675. MedChemExpress MCE
PPO21 PPO21. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(Diphenylphosphoryl)-9-(4-(diphenylphosphoryl)phenyl)-9H -carbazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1226860-68-9. Molecular formula: C42H31NO2P2. Mole weight: 643.65 g/mol. Purity: 95%+. IUPACName: 3-diphenylphosphoryl-9-(4-diphenylphosphorylphenyl)carbazole. Canonical SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=C(C=C3)N4C5=C(C=C(C=C5)P(=O)(C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C84. Product ID: ACM1226860689. Alfa Chemistry — ISO 9001:2015 Certified. Categories: PP-20 Chakwal-I. Alfa Chemistry.
PPO27 PPO27. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Bis(diphenylphosphoryl)-9-phenyl-9H -carbazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1299463-56-1. Molecular formula: C42H31NO2P2. Mole weight: 643.65 g/mol. Product ID: ACM1299463561. Alfa Chemistry — ISO 9001:2015 Certified. Categories: PP-269 Muzaffargarh-II. Alfa Chemistry. 2
p,p-Octylidenebisphenol p,p-Octylidenebisphenol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p,p-octylidenebisphenol ;4,4-Octylidenebisphenol. Product Category: Heterocyclic Organic Compound. CAS No. 1233-26-7. Molecular formula: C20H26O2. Mole weight: 298.41924. Purity: 0.96. IUPACName: 4-[1-(4-hydroxyphenyl)octyl]phenol. Product ID: ACM1233267. Alfa Chemistry — ISO 9001:2015 Certified. Categories: p,p'-Octylidenebisphenol. Alfa Chemistry. 3
PPOH PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. Synonyms: 6-(2-propargyloxyphenyl)hexanoic acid. Grades: ≥99%. CAS No. 206052-01-9. Molecular formula: C15H18O3. Mole weight: 246.3. BOC Sciences 11
PPOH PPOH, a fatty acid derivative, is a selective cyclooxygenase ( COX ) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC 50 values of 22 μM and 6.5 μM, respectively [1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 206052-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119647. MedChemExpress MCE
Ppolypropylene(melt flow rate), melt flow rate 11.30g/10min Ppolypropylene(melt flow rate), melt flow rate 11.30g/10min. Group: Polypropylene (pp). CAS No. 9003-07-0. Molecular formula: 42.08g/mol. Mole weight: [CH2CH(CH3)]n. Alfa Chemistry Materials 3
PPPA PPPA. Group: Biochemicals. Grades: Purified. CAS No. 113190-92-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PPPA PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki=0.13, 0.47, 1.10 and 3.86 μM for GluN2A, GluN2B, GluN2C and GluN2D subunits respectively). Some findings support the hypothesis that PPPA and reward synergize to enhance initiate dopamine (DA) excitation. Synonyms: (2R*,4S*)-4-(3-Phosphonopropyl)-2-piperidinecarboxylic acid. CAS No. 113190-92-4. Molecular formula: C9H18NO5P. Mole weight: 251.22. BOC Sciences 10
p-[[p-(phenylazo)phenyl]azo]phenol p-[[p-(phenylazo)phenyl]azo]phenol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Disperse Yellow 23;Disperse Yellow RGFL (C.I. Disperse Yellow 23). Product Category: Disperse Dyes. CAS No. 6250-23-3. Molecular formula: C18H14N4O. Mole weight: 302.336. Density: 1.19 g/cm³. Product ID: ACM6250233. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PPP hydrochloride PPP hydrochloride is a selective inactivator of human cytochrome P450 2B6 (CYP2B6). Synonyms: 1-(2-phenylpropan-2-yl)piperidine hydrochloride; 1-(alpha,alpha-Dimethylbenzyl)piperidine hydrochloride. Grades: 99%. CAS No. 21602-56-2. Molecular formula: C14H21N.HCl. Mole weight: 239.78. BOC Sciences 11
p,p',p''-tris(dimethylamino)tritylium m-[(p-anilinophenyl)azo]benzenesulphonate p,p',p''-tris(dimethylamino)tritylium m-[(p-anilinophenyl)azo]benzenesulphonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p,p',p''-tris(dimethylamino)tritylium m-[(p-anilinophenyl)azo]benzenesulphonate;Methylium, tris4-(dimethylamino)phenyl-, salt with 3-4-(phenylamino)phenylazobenzenesulfonic acid (1:1);4,4',4''-Tris(dimethylamino)tritylium 3-[(4-anilinophenyl)azo]benzenes. Product Category: Solvent Dyes. CAS No. 65294-17-9. Molecular formula: C25H30N3.C18H14N3O3S. Mole weight: 724.92. Purity: 0.96. IUPACName: 3-(4-anilinophenyl)diazenylbenzenesulfonate; [4-[bis(4-dimethylaminophenyl)methylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium. Product ID: ACM65294179. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Solvent Black 46. Alfa Chemistry. 2
PPQ 102 PPQ 102. Group: Biochemicals. Grades: Purified. CAS No. 931706-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PPQ-102 PPQ-102 is a remarkable and highly specialized inhibitor, used in studying prostate cancer. Synonyms: PPQ-102; PPQ102; PPQ 102. CAS No. 931706-15-9. Molecular formula: C26H22N4O3. Mole weight: 438.487. BOC Sciences 10
p-Propylacetophenone Liquid, d20 0.98. CAS No. 2932-65-2. Pack Sizes: 25g. Product ID: FR-0376. B.P. 155-158/18 mm. Mole weight: 162.23. Frinton Laboratories Inc
Frinton Laboratories
Pps I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 20% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 25U; 125U. GAGTC(N)4↑ CTCAG(N)5&darr. Activity: 500-1000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Pseudomonas pseudoalcaligenes. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA and 50% glycerol. Cat No: ET-1149RE. Creative Enzymes
PPT PPT, also known as Propyl pyrazole triol, is an ERα selective agonist with a 410-fold relative binding affinity for ERα (49%) versus ERβ (0.12%) and therefore activates gene transcription only through ER&alpha. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury. PPT also exerts anti-diabetic effects in mouse models. Synonyms: 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol; Propyl pyrazole triol. Grades: ≥99% by HPLC. CAS No. 263717-53-9. Molecular formula: C24H22N2O3. Mole weight: 386.45. BOC Sciences 10
PPT PPT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,8-Bis(diphenylphosphoryl)dibenzo[b,d]thiophene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1019842-99-9. Molecular formula: C36H26O2P2S. Mole weight: 584.60 g/mol. Product ID: ACM1019842999-2. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
PPT sublimed. Group: Oled and pled materials. Alfa Chemistry Analytical Products 4
PPT PPT. Group: Biochemicals. Grades: Purified. CAS No. 263717-53-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PPTN PPTN is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160271-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-110322A. MedChemExpress MCE
PPTN hydrochloride PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110322. MedChemExpress MCE
PPTN hydrochloride PPTN, a 4,7-disubstituted 2-naphthoic acid derivative, is a high affinity and selective P2Y14 antagonist (KB = 434 pM) with >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN blocks UDP-glucose-promoted chemotaxis of human neutrophils and does so across a concentration range consistent with its KB determined in the P2Y14-R-expressing cell line. Synonyms: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1992047-65-0. Molecular formula: C29H24F3NO2.HCl. Mole weight: 511.96. BOC Sciences 10
PPY A PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinases (IC50= 9 and 20 nM, respectively) that inhibits growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene. Synonyms: 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide. Grades: ≥98% by HPLC. CAS No. 875634-01-8. Molecular formula: C22H20N4O2. Mole weight: 372.42. BOC Sciences 10
PPY A PPY A. Group: Biochemicals. Grades: Purified. CAS No. 875634-01-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PPZ2 PPZ2 is a diacylglycerol (DAG)-activated TRPC3/TRPC6/TRPC7 channel activator with activity in promoting neuronal development and survival. PPZ2 activates recombinant TRPC3/TRPC6/TRPC7 channels in a dose-dependent manner without affecting other TRPC channels. PPZ2 elicits cation currents and calcium ion (Ca(2+)) influx in cultured central neurons. PPZ2 is able to induce BDNF-like neurite outgrowth and neuroprotection, an effect that disappears after TRPC3/TRPC6/TRPC7 knockdown or inhibition. PPZ2 also increases the activation of the calcium-dependent transcription factor cAMP response element binding protein. The effects of PPZ2 suggest that calcium signaling mediated by activation of DAG-activated TRPC channels plays an important role in its neurotrophic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896203-18-2. Pack Sizes: 5 mg. Product ID: HY-111527. MedChemExpress MCE
PPZ2 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PQ-10 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PQ-10 PQ-10 is a potent inhibitor of Phosphodiesterase 10A ( PDE10A ) with IC 50 and ED 50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 927691-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18078. MedChemExpress MCE
PQ-10 PQ-10 is a potent and selective inhibitor of phosphodiesterase type 10 (PDE10). Synonyms: 6,7-dimethoxy-4-[(3R)-3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]quinazoline. Grades: ≥98%. CAS No. 927691-21-2. Molecular formula: C22H21N5O3. Mole weight: 403.4. BOC Sciences 10
PQ1 succinate ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PQ401 ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PQ 401 PQ 401 is an IGF-1R inhibitor and inhibits autophosphorylation of the IGF-IR kinase domain at concentrations <100 nM, with an IC50 <1μM. Synonyms: PQ401; PQ-401; PQ 401. Grades:>98%. CAS No. 196868-63-0. Molecular formula: C18H16ClN3O2. Mole weight: 341.79. BOC Sciences 10
PQ 401 PQ 401. Group: Biochemicals. Grades: Purified. CAS No. 196868-63-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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PQ 69 PQ 69 is a potent and selective A1 receptor inverse agonist, with high binding affinity at A1 receptor (Ki= 0.07 and 0.96 nM for rat and human receptors respectively). It exhibits 217-fold more selective compared with hA2A receptors and >1,000-fold selectivity for hA1 over hA3 receptor. PQ-69 exhibits potent antagonist effects on A1AR in vitro, ex vivo and in vivo. Synonyms: 4-(Butylamino)-2-(3-fluorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one; PQ-69; PQ 69; PQ69. Grades: ≥98% by HPLC. CAS No. 910045-32-8. Molecular formula: C20H19FN4O. Mole weight: 350.39. BOC Sciences 10
PQ912 PQ912 Inhibitor. Uses: Scientific use. Product Category: T22403. CAS No. 1276021-65-8. TARGETMOL CHEMICALS
PQCA This active molecular is a muscarinic M1 receptor positive allosteric modulator which is able to improve cognitive measures in rat and rhesus monkeys. PQCA is very efficient in rodent and nonhuman primate (NHP) cognition assays and it can improve performance on translatable tests of Memory and Attention in rhesus monkeys. PQCA attenuates learning and memory deficits in Alzheimer's disease model. PQCA may be potential useful in treating Alzheimer's diseases in the future. Uses: Treatment of alzheimer's diseases. Synonyms: 1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid,1401512-98-8 (sodium). Grades: 98%. CAS No. 1144504-35-7. Molecular formula: C22H20N4O3. Mole weight: 388.43. BOC Sciences 10
PQCA PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA has an EC 50 value of 49 nM and 135 nM on rhesus and human M1 receptor , respectively. PQCA is inactive for other muscarinic receptors. PQCA has potential to reduce the cognitive deficits associated with Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1144504-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118342. MedChemExpress MCE
PQQ DISODIUM SALT PQQ DISODIUM SALT, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. CAS No. 122628-50-6. Product ID: CDF4-0242. Molecular formula: C14H4N2Na2O8. Category: Nutrients. Product Keywords: Nutrients; PQQ DISODIUM SALT; CDF4-0242; Nutrients; C14H4N2Na2O8; 122628-50-6. EC Number: 209-118-9. Storage: 2-8°C. Applications: Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function. Product Description: Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function. CD Formulation
PQR309 PQR309, a pan inhibitor of phosphoinositide-3-kinases, is still under Phase II clinical trial against Glioblastoma and Lymphoma. Uses: Pqr309 is a pan inhibitor of phosphoinositide-3-kinases and is still under phase ii clinical trial against glioblastoma and lymphoma. Synonyms: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine; PQR309; PQR-309; PQR309; Bimiralisib free base. Grades: 98%. CAS No. 1225037-39-7. Molecular formula: C17H20F3N7O2. Mole weight: 411.38. BOC Sciences 10
PQR530 PQR530 is a potent dual pan PI3K/mTOR inhibitor undergoing phase II clinical trials in 2016. Aberrant activation of the PI3K/mTOR signaling pathway promotes the growth of malignant tumor cells. Study showed that PQR530 inhibited all PI3K isoforms and the mammalian target of rapamycin (mTOR) complexes C1/2 potently and selectively against tumor progression. Synonyms: PQR530; PQR0530; PQR 530. (S)-4-(difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine. Grades: ≥98%. CAS No. 1927857-61-1. Molecular formula: C18H23F2N7O2. Mole weight: 407.42. BOC Sciences 10
PQR620 PQR620 is an orally bioavailable and selective brain penetrant inhibitor of mTORC1/2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1927857-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100026. MedChemExpress MCE
PqsR/LasR-IN-3 PqsR/LasR-IN-3 (Compound 7a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-3 also inhibits hERG with the IC 50 of 109.01 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2581109-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146329. MedChemExpress MCE
PQT-12 Band gap: 2.27 eV. Uses: Pqt-12 is a solution processable p-type, π-conjugated semiconductor for felxible printed electronics such as high sensitivity chemical sensors based on organic thin film transistors. it can also be used as donor material in organic solar cells.researches show that the microstructure of pqt-12 can be controled by the choice of solvent.study has shown pqt-12 spin-coated on a donor substrate can be t. Additional or Alternative Names: Poly(3,3'''-didodecyl[2,2':5',2'':5'',2'''-quaterthiophene]-5,5'''-diyl),Poly(4,4''-didodecyl[2,2':5',2'':5'',2'''-quaterthiophene]-5,5'''-diyl). Product Category: Flexible Printed Electronics. CAS No. 827343-06-6. Molecular formula: (C40H56S4)n. Product ID: ACM827343066. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Pgt 126.… Alfa Chemistry.
p-Quaterphenyl p-Quaterphenyl. Group: Carbon nano materials electroluminescence materials. CAS No. 135-70-6. Product ID: 1-phenyl-4-(4-phenylphenyl)benzene. Molecular formula: 306.4g/mol. Mole weight: C24H18. C1=CC=C (C=C1)C2=CC=C (C=C2)C3=CC=C (C=C3)C4=CC=CC=C4. InChI=1S/C24H18/c1-3-7-19 (8-4-1)21-11-15-23 (16-12-21)24-17-13-22 (14-18-24)20-9-5-2-6-10-20/h1-18H. GPRIERYVMZVKTC-UHFFFAOYSA-N. Alfa Chemistry Materials 5
P-Quaterphenyl, 99.5+% Laser Dye P-Quaterphenyl, 99.5+% Laser Dye. CAS No: 135-70-6 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
p-Quinquephenyl p-Quinquephenyl. Group: Carbon nano materials electroluminescence materials. CAS No. 3073-05-0. Product ID: 1,4-bis(4-phenylphenyl)benzene. Molecular formula: 382.5g/mol. Mole weight: C30H22. C1=CC=C (C=C1)C2=CC=C (C=C2)C3=CC=C (C=C3)C4=CC=C (C=C4)C5=CC=CC=C5. InChI=1S/C30H22/c1-3-7-23 (8-4-1)25-11-15-27 (16-12-25)29-19-21-30 (22-20-29)28-17-13-26 (14-18-28)24-9-5-2-6-10-24/h1-22H. OMCUOJTVNIHQTI-UHFFFAOYSA-N. Alfa Chemistry Materials 5
PR-073 PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 has a high potency (Ki = 89 nM) and selectivity. Its oral bioavailability in the mouse is 17% as well as half-life is 3.4 h after oral dosing. Uses: The treatment of inflammatory bowel disease (ibd). Synonyms: PR-073; PR 073; PR073. BOC Sciences 10
PR-104 PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851627-62-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16405. MedChemExpress MCE
PR-104 PR-104 is a non-toxic, small-molecule, hypoxia-activated, 3,5-dinitrobenzamide nitrogen mustard pre-prodrug with potential antitumor activity. Upon intravenous administration, PR-104 is converted by systemic phosphatases to the alcohol intermediate PR-104A, which is reduced to form the active DNA-crosslinking mustard species hydroxylamine PR-104H intracellularly under hypoxic conditions. PR-104H specifically crosslinks hypoxic tumor cell DNA, resulting in the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis in susceptible hypoxic tumor cell populations while sparing normoxic tissues. Synonyms: PR 104; PR104; 2- ( (2-Bromoethyl) (2, 4-dinitro-6- ( (2- (phosphonooxy) ethyl) carbamoyl) phenyl) amino) ethyl methanesulfonate; Benzamide, 2-[(2-bromoethyl)[2-[(methylsulfonyl)oxy]ethyl]amino]-3,5-dinitro-N-[2-(phosphonooxy)ethyl]-. Grades: ≥97%. CAS No. 851627-62-8. Molecular formula: C14H20BrN4O12PS. Mole weight: 579.27. BOC Sciences 11
PR 37454 PR 37454 is a polyether antibiotic produced by Streptomyces gypseus DS 27461. It is active against gram-positive bacteria and coccidium. Synonyms: PR-37454; PR37454. Molecular formula: C48H82O18. Mole weight: 947.15. BOC Sciences 5
PR 39 (porcine) PR 39 (porcine) is a gene-encoded, proline-arginine-rich porcine antimicrobial peptide with multiple biological functions. It might function in the inflammatory milieu not only to kill bacteria, but also to aid in modulating the viability of inflammatory cells by regulating apoptosis. Uses: Anti-bacterial agents. Synonyms: PR39 (porcine); PR-39 (porcine); H-RRRPRPPyl PRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2; H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2; L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-tyrosyl-L-leucyl-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-leucyl-L-prolyl-L-prolyl-L-arginyl-L-isoleucyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolinamide. Grades: >98%. CAS No. 139637-11-9. Molecular formula: C229H346N70O40. Mole weight: 4719.74. BOC Sciences 3
PR 619 PR 619. Group: Biochemicals. Alternative Names: Thiocyanic Acid C,C'-(2,6-Diamino-3,5-pyridinediyl) Ester; Thiocyanic Acid C,C'-(2,6-Diamino-3,5-pyridinediyl) Ester; 2,6-Diamino-3,5-dithiocyanopyridine. Grades: Highly Purified. CAS No. 2645-32-1. Pack Sizes: 25mg. Molecular Formula: C7H5N5S2, Molecular Weight: 223.28. US Biological Life Sciences. USBiological 3
Worldwide
PR-619 ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PR-619 PR-619 is a broad-range and reversible DUB inhibitor with EC50s of 3.93, 4.9, 6.86, 7.2, and 8.61 ?M for USP4, USP8, USP7, USP2, and USP5, respectively. PR-619 induces ER Stress and ER-Stress related apoptosis[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2645-32-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13814. MedChemExpress MCE
PR-619 Broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells. Synonyms: PR-619; PR 619; PR619. CAS No. 2645-32-1. Molecular formula: C7H5N5S2. Mole weight: 223.272. BOC Sciences 10
Pracinostat Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies. Group: Biochemicals. Alternative Names: (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxyacrylamide; (E)-3-[2-Butyl-1-(2-diethylaminoethyl)-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide; Kaempferol 3-O- β-D-(6-E-p-Coumaroylglucoside); SB 939; SB939; (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide. Grades: Highly Purified. CAS No. 929016-96-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide

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