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The enzyme is involved in the biosynthesis of the phytotoxin solanapyrone by some fungi. The bifunctional enzyme catalyses the oxidation of prosolanapyrone II and the subsequent Diels Alder cycloisomerization of the product prosolanapyrone III to (-)-solanapyrone A (cf. EC 5.5.1.20, prosolanapyrone III cycloisomerase). Group: Enzymes. Synonyms: Sol5 (ambiguous); SPS (ambiguous); solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cycloisomerase); prosolanapyrone II oxidase. Enzyme Commission Number: EC 1.1.3.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0415; prosolanapyrone-II oxidase; EC 1.1.3.42; Sol5 (ambiguous); SPS (ambiguous); solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cycloisomerase); prosolanapyrone II oxidase. Cat No: EXWM-0415.
Prosomatostatin
Somatostatin 1-28 is a somatostatin receptor agonist derived from the post-translational cleavage of prosomatostatin. Synonyms: Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys17-Cys28); Somatostatin, pro-; ProSRIF; Somatostatin 1-28; SRIF-28; SRIF 28; SRIF28; Somatostatin 28. Grades: >98%. CAS No. 74315-46-1. Molecular formula: C137H207N41O39S3. Mole weight: 3148.55.
Heterocyclic Organic Compound. Alternative Names: 11-DEOXY-11-METHYLENE PROSTAGLANDIN D2;9ALPHA,15S-DIHYDROXY-11-METHYLENE-PROSTA-5Z,13E-DIEN-1-OIC ACID. CAS No. 100648-29-1. Molecular formula: C21H34O4. Mole weight: 350.49. Appearance: A solution in methyl acetate. Purity: 0.96. IUPACName: 7-[5-hydroxy-2-(3-hydroxyoct-1-enyl)-3-methylidenecyclopentyl]hept-5-enoic acid. Canonical SMILES: CCCCCC (C=CC1C (C (CC1=C)O)CC=CCCCC (=O)O)O. Catalog: ACM100648291.
Prostacyclin sodium salt
Prostacyclin sodium salt. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-6,9-epoxy-11,15-dihydroxy-prosta-5,13-dien-1-oic acid sodium salt; Epoprostenol sodium; Flolan. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C20H32NaO5. US Biological Life Sciences.
Worldwide
Prostaglandin A1
Prostaglandin A1 can inhibit HIV-1 replication in various cell types. It can also activate pro-inflammatory PGD2 receptor CRTH2 initiating the anti-inflammatory response. Uses: Antiviral agents. Synonyms: 2-(3-Hydroxy-1-octenyl)-5-oxo-3-cyclopentene-1-heptanoic Acid; 15-Hydroxy-9-oxoprosta-10,13-dienoic Acid; 15α-Hydroxy-9-ketoprosta-10,13-dienoic Acid; 15α-Hydroxy-9-oxo-10,13E-prostadienoic Acid; PGA1; Prostaglandin A1; Prostaglandin E1-217. Grades: > 95%. CAS No. 14152-28-4. Molecular formula: C20H32O4. Mole weight: 336.48.
prostaglandin-A1 Δ-isomerase
Interconverts prostaglandin A1 and prostaglandin C1. Group: Enzymes. Synonyms: prostaglandin A isomerase. Enzyme Commission Number: EC 5.3.3.9. CAS No. 9055-01-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5506; prostaglandin-A1 Δ-isomerase; EC 5.3.3.9; 9055-01-0; prostaglandin A isomerase. Cat No: EXWM-5506.
Prostaglandin A1 methyl ester
Prostaglandin A1 (PGA1) methyl ester is a lipophilic analog of PGA1. PGA1 is a prostaglandin that exhibits anti-inflammatory effects and has been shown to cause renal vasodilation, increase urine sodium excretion, and lower arterial pressure in hypertensive patients. Synonyms: PGA1 methyl ester; Methyl 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoate. Grades: ≥98%. CAS No. 26771-94-8. Molecular formula: C21H34O4. Mole weight: 350.5.
Prostaglandin A2
PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It shows some antiviral/antitumor activity. Synonyms: (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic Acid; 7-[2-(3-Hydroxy-1-octenyl)-5-oxo-3-cyclopenten-1-yl]-5-heptenoic Acid; (+)-Prostaglandin A2; (15S)-PGA2; 15(S)-Hydroxy-9-oxo-5-cis- 10,13-trans-prostatrienoic Acid; 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostenoic Acid; 15(S)-Prostaglandin A2; 15α-Hydroxy-9-oxo-cis-5,10,trans- 13-prostatrienecarboxylic Acid; 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienoic Acid; 5,6-cis-PGA2; Medullin; NSC 165561; PGA2. Grades: > 95%. CAS No. 13345-50-1. Molecular formula: C20H30O4. Mole weight: 334.46.
Prostaglandin A2
Prostaglandin A2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. Prostaglandin A2 is generally not present in mammals. Prostaglandin A2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. Prostaglandin A2 has also been shown to act as a vasodilator with natriuretic properties. Group: Biochemicals. Alternative Names: (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic Acid; 7-[2-(3-Hydroxy-1-octenyl)-5-oxo-3-cyclopenten-1-yl]-5-heptenoic Acid; (+)-Prostaglandin A2; (15S)-PGA2; 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostatrienoic Acid; 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostenoic Acid; 15(S)-Prostaglandin A2; 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienecarboxylic Acid; 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienoic Acid; 5,6-cis-PGA2; Medullin; NSC 165561; PGA2. Grades: Highly Purified. CAS No. 13345-50-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Prostaglandin A2 methyl ester
Prostaglandin A2 (PGA2) methyl ester is a lipophilic analog of PGA2. PGA2 is a prostaglandin formed by the dehydration of PGE2. PGA2 was shown to block the cell cycle progression of NIH 3T3 cells at G1 and G2/M. Synonyms: Medullin methyl ester; PGA2 methyl ester; 15S-Hydroxy-9-oxo-methyl ester-prosta-5Z,10,13E-trien-1-oic acid; Methyl (Z)-7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoate. Grades: ≥98%. CAS No. 31753-19-2. Molecular formula: C21H32O4. Mole weight: 348.5.
Prostaglandin A3
Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively, in a radioligand binding assay. Synonyms: PGA3; (Z)-7-[(1R)-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 36614-31-0. Molecular formula: C20H28O4. Mole weight: 332.4.
Prostaglandin (Alprostadil) EP Impurity D
Prostaglandin (Alprostadil) EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20897-91-0. Molecular Formula: C20H34O5. Mole Weight: 354.49. Catalog: APB20897910.
Prostaglandin (Alprostadil) EP Impurity F
Prostaglandin (Alprostadil) EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21003-46-3. Molecular Formula: C20H34O5. Mole Weight: 354.49. Catalog: APB21003463.
Prostaglandin B1
Prostaglandin B1 is a novel microbial biopolymer. Itcan improve the longevity of type 2 diabetic rodents. Synonyms: 2-(3-Hydroxy-1-octenyl)-5-oxo-1-cyclopentene-1-heptanoic Acid; 15-Hydroxy-9-oxoprosta-8(12),13-dienoic Acid; 15α-Hydroxy-9-ketoprosta-8(12),13-dienoic Acid; 15α-Hydroxy-9-oxo-8(12),13E-prostadienoic Acid; PGB1; PGE1-278; Prostaglandin B1; Prostaglandin E1-278. Grades: > 95%. CAS No. 13345-51-2. Molecular formula: C20H32O4. Mole weight: 336.48.
Prostaglandin B2
Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13367-85-6. Pack Sizes: 1 mg (29.90 mM * 100 μL in Methyl acetate); 5 mg (29.90 mM * 500 μL in Methyl acetate). Product ID: HY-113042.
Prostaglandin B2
Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base. Synonyms: PGB2; (Z)-7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopenten-1-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 13367-85-6. Molecular formula: C20H30O4. Mole weight: 334.5.
Prostaglandin D2 (PGD2) is the major eicosanoid product found in mast cells and brain. It has been shown to induce inflammation such as allergic asthma. Synonyms: PGD2; 11-Dehydroprostaglandin F2-alpha; (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid. Grades: ≥95%. CAS No. 41598-07-6. Molecular formula: C20H32O5. Mole weight: 352.5.
Prostaglandin D2
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals [1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances [2]. PGD2 plays a protective role by suppressing inflammation [3]. Uses: Scientific research. Group: Natural products. Alternative Names: PGD2. CAS No. 41598-07-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101988.
Prostaglandin D2
Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma. Prostaglandin D2 is the major postagrlandin produced by mast cells and is the primary prostaglandin in the brain. It causes vasodilation, induces inflammation, and its presence in hair follicles may be partially responsible for male pattern baldness. Prostaglandin D2 is released during asthmatic and allergic reactions. Group: Biochemicals. Alternative Names: (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid; 11-Dehydroprostaglandin F2alpha, PGD2. Grades: Highly Purified. CAS No. 41598-07-6. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C20H32O5, Molecular Weight: 352.5. US Biological Life Sciences.
Worldwide
Prostaglandin D2 Ethanolamide-d4
Prostaglandin D2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: N-(2-Hydroxyethyl)-11-oxo-9α,15S-dihydroxyprosta-5Z,13E-dien-1-amide-d4. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences.
Worldwide
prostaglandin-D synthase
Brings about the opening of the epidioxy bridge. Some enzymes require glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 Δ-isomerase; prostaglandin-R-prostaglandin D isomerase; PGH-PGD isomerase(5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate Δ-isomerase (incorrect); (5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase; prostaglandin endoperoxide Δ-isomerase; prostaglandin D synthetase. Enzyme Commission Number: EC 5.3.99.2. CAS No. 65802-85-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5510; prostaglandin-D synthase; EC 5.3.99.2; 65802-85-9; prostaglandin-H2 Δ-isomerase; prostaglandin-R-prostaglandin D isomerase; PGH-PGD isomerase(5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate Δ-isomerase (incorrect); (5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase; prostaglandin endoperoxide Δ-isomerase; prostaglandin D synthetase. Cat No: EXWM-5510.
Prostaglandin E1
Prostaglandin-E1 is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It can be used as a vasodilator agent increasing peripheral blood flow. Uses: The treatment of erectile dysfunction, vasodilator agent. Synonyms: l-PGE1; l-Prostaglandin E1; Lipoprost; Liprostin; Minprog; NSC 165559; ONO 1608; PGE-1; Promostan; Prostaglandin E1; Prostandin; Alprostadil; Topiglan; Vasaprostan. U 10136; U-10,136. Grades: 95%~105% (Assay). CAS No. 745-65-3. Molecular formula: C20H34O5. Mole weight: 354.48.
Prostaglandin E1
1mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H34O5. CAS No. 745-65-3. Prepack ID 13337083-1mg. Molecular Weight 354.48. See USA prepack pricing.
Prostaglandin E1
A primary Prostaglandin; easily crystallized from purified biological extracts. Vasodilator (peripheral). Group: Biochemicals. Alternative Names: (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic Acid; Alprostadil; Alprox TD; Caveject; Liprostin; ONO 1608; PGE1; Palux. Grades: Highly Purified. CAS No. 745-65-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Prostaglandin E1
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K i s of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3 , EP4 , EP2 , IP and EP1 , respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Alprostadil; PGE1. CAS No. 745-65-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0131.
Prostaglandin E1 alcohol
Prostaglandin E1 (PGE1) alcohol is a bronchodilator with low irritancy, exhibiting relaxant activity on the human bronchial muscle via vasodilation of blood vessels. Synonyms: 1-Hydroxy prostaglandin E1; PGE1 Alcohol; (2R,3R,4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentan-1-one. Grades: ≥99%. CAS No. 21562-57-2. Molecular formula: C20H36O4. Mole weight: 340.5.
Prostaglandin E2
Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Group: Natural products. Alternative Names: PGE2; Dinoprostone. CAS No. 363-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952.
Prostaglandin E2
Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Uses: Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Synonyms: Dinoprostone; PGE2; Prostin E2; Prepidil. Grades: >98%. CAS No. 363-24-6. Molecular formula: C20H32O5. Mole weight: 352.47.
prostaglandin-E2 9-reductase
Reduces prostaglandin E2 to prostaglandin F2&alpha. A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds. May be identical with EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Enzyme Commission Number: EC 1.1.1.189. CAS No. 42613-35-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0091; prostaglandin-E2 9-reductase; EC 1.1.1.189; 42613-35-4; PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Cat No: EXWM-0091.
Prostaglandin E2 (Dinoprostone)
The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. Inhibits NLRP3 by acting through receptor EP4 activation that increases cAMP and phosphorylates NLRP3 at serine 295 through PKA. PKA phosphorylation of NLRP3 inhibits the NLRP3 ATPase activity, which is required for assembly of NLRP3-ASC complexes. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid; (-)-Prostaglandin E2; (15S)-Prostaglandin E2; Cervidil; Cerviprime; Cerviprost; Dinoprostone; Minprostin E2; PGE2; Prepidil. Grades: Highly Purified. CAS No. 363-24-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Prostaglandin E2 ethanolamide
Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 with improved water solubility. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA) and acts as an agonist of E prostanoid (EP) receptors 1-4 with Ki values of 2.45, 0.46, 0.2, and 0.51 μM, respectively. Synonyms: Dinoprostone ethanolamide; PGE2-EA; Prostamide E2; N-(11R,15S-dihydroxy-9-oxo-5Z,13E-prostadienoyl)-ethanolamine; (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; PGE2 ethanolamide; Prostaglandin E2-EA; N-(2-hydroxyethyl)-9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide. Grades: ≥98%. CAS No. 194935-38-1. Molecular formula: C22H37NO5. Mole weight: 395.53.
Prostaglandin E2 Ethanolamide-d4
Prostaglandin E2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; Prostamide E2; PGE2 ethanolamide. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences.
Worldwide
prostaglandin-endoperoxide synthase
This enzyme acts both as a dioxygenase and as a peroxidase. Group: Enzymes. Synonyms: prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Enzyme Commission Number: EC 1.14.99.1. CAS No. 39391-18-9. COX-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1031; prostaglandin-endoperoxide synthase; EC 1.14.99.1; 39391-18-9; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: EXWM-1031.
A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb = 17.8nM). Exhibits about 300-fold selectivity for the EP2 receptor over human EP3, EP4, and IP receptors, about 100- fold selectivity over human EP1, 25-fold selectivity against human FP and TP, and 10-fold selectivity against human DP1 receptors. Does not affect the activity of about 40 enzymes, ion channels, receptors, and neurotransmitters even at higher concentrations (10uM). Shown to significantly reduce the induction of several inflammatory cytokines and chemokines and reduces the opening of blood-brain barrier during neuronal inflammation. Displays good pharmacokinetic properties with a half-life of 1.6 h and brain to plasma ratio of 1.6 in a murine model (5mg/kg i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences.
Worldwide
prostaglandin-E synthase
Brings about the opening of the epidioxy bridge. Requires glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Enzyme Commission Number: EC 5.3.99.3. CAS No. 52227-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5511; prostaglandin-E synthase; EC 5.3.99.3; 52227-79-9; prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Cat No: EXWM-5511.
Prostaglandin F1a
Prostaglandin F1a is a compound that has the effect of contracting smooth muscle and lowering blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 745-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113459.
Prostaglandin F2a
Prostaglandin F2a. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic acid; (+)-Prostaglandin F2a. Grades: Highly Purified. CAS No. 551-11-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H34O5. US Biological Life Sciences.
Worldwide
Prostaglandin F2α
Prostaglandin F2α. Group: Biochemicals. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Prostaglandin F2α alcohol
Prostaglandin F2α alcohol (PGF2α-OH) is an analog of PGF2α and a weak agonist. Synonyms: AGN 190190; PGF2α-OH; ZK 62717; Prostaglandin F2alpha alcohol; 1,9S,11R,15S-tetrahydroxy-5Z,13E-prostadiene; (1R,3S,4R,5R)-4-[(Z)-7-hydroxyhept-2-enyl]-5-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentane-1,3-diol. Grades: ≥98%. CAS No. 13261-27-3. Molecular formula: C20H36O4. Mole weight: 340.5.
Prostaglandin F2α (PGF2α) dimethyl amide is a derivative of PGF2α and a weak FP receptor antagonist. Synonyms: Dinoprost dimethyl amide; PGF2α dimethyl amide; N,N-Dimethyl-9alpha, 11alpha, 15S-trihydroxy-prosta-5Z, 13E-dien-1-amide. Grades: ≥98%. CAS No. 68192-15-4. Molecular formula: C22H39NO4. Mole weight: 381.6.
Prostaglandin F2α dimethyl amine
PGF2α dimethyl amine is a derivative of PGF2α that acts as a PG antagonist and a weak FP receptor antagonist. Synonyms: Dinoprost dimethyl amine; PGF2α dimethyl amine; PGE2alpha dimethyl amine; N-Dimethylaminoprostaglandin F2alpha; 1-dimethylamino-9S,11R,15S-trihydroxy-5Z,13E-prostadiene; (1R,3S,4R,5R)-4-[(Z)-7-(dimethylamino)hept-2-enyl]-5-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentane-1,3-diol. Grades: ≥98%. CAS No. 67508-09-2. Molecular formula: C22H41NO3. Mole weight: 367.6.
Prostaglandin F2α (tromethamine salt)
Cas No. 38562-01-5.
Prostaglandin F2α tromethamine salt
Prostaglandin F2α is a naturally-occurring prostaglandin and potent vasoconstrictor, exhibiting luteolytic activity. Uses: Abortifacient agents, nonsteroidal. Synonyms: U 14585; U14585; U-14585; Dinoprost tromethamine salt; Dinolytic; Zinoprost; Prostin F2 alpha. Grades: ≥98%. CAS No. 38562-01-5. Molecular formula: C20H34O5.C4H11NO3. Mole weight: 475.62.
Prostaglandin F2α Tromethamine Salt
One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both. Group: Biochemicals. Alternative Names: (5Z, 9α, 11α, 13E, 15S)-9, 11, 15-Trihydroxyprosta-5, 13-dien-1-oic Acid 2-Amino-2-(hydroxymethyl)-1,3-propanediol; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid Tromethamine; (+)-Prostaglandin F2α Tromethamine; 9α, 11α, 15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid Tromethamine; 9α,11α-PGF2 Tromethamine; 9α,11α-PGF2α Tromethamine; Prostaglandin F2α-tham; THAM PGF2α; Tromethamine Prostaglandin F2α; U 14583E; U 14585. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Prostaglandin F(2)(a) tris salt
Prostaglandin F(2)(a) tris salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 25mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Prostaglandin F2β
Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α and acts as a PGF2α activity antagonist. It also can be used as a bronchodilator. Synonyms: PGF2β; PGF2beta; Prostaglandin F2b; PGF2b. Grades: ≥95%. CAS No. 4510-16-1. Molecular formula: C20H34O5. Mole weight: 354.49.
Prostaglandin F3α
PGF3α is a COX metabolite of EPA. It acts as a weak FP receptor antagonist. Synonyms: PGF3α; PGF3alpha; Prostaglandin F3alpha; 9S,11R,15S-trihydroxy-5Z,13E,17Z-prostatrienoic acid; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 745-64-2. Molecular formula: C20H32O5. Mole weight: 352.5.
prostaglandin-F synthase
Reduces prostaglandin D2 and prostaglandin H2 to prostaglandin F2; prostaglandin D2 is not an intermediate in the reduction of prostaglandin H2. Also catalyses the reduction of a number of carbonyl compounds, such as 9,10-phenanthroquinone and 4-nitroacetophenone. Group: Enzymes. Synonyms: prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. PGF synthetase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0090; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9; prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Cat No: EXWM-0090.
Prostaglandin F Synthase from human, Recombinant
PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways. Applications: Prostaglandin f synthase (pgf synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. prostaglandin f synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. pgf synthase is also used to study kidney and renal cell carcinoma. Group: Enzymes. Synonyms: prostaglandin-D2 11-reduc. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. Purity: > 90% (SDS-PAGE). PGF synthetase. Mole weight: mol wt ~37 kDa. Storage: -70°C. Source: E. coli. Species: Human. prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; prostaglandin-D2 11-reductase; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9. Cat No: NATE-0552.
Prostaglandin H1
Prostaglandin H1 (PGH1) is a COX metabolite of DGLA and is the precursor to all 1-series PGs and thromboxanes. PGH1 is a suicide inhibitor of platelet thromboxane synthase with Ki value of 28 μM. Synonyms: PGH1; 9S,11R-epidioxy-15S-hydroxy-13E-prostaenoic acid; 9alpha,11alpha-epidioxy-15(S)-hydroxy-13-trans-prostenoic acid. Grades: ≥95%. CAS No. 52589-22-7. Molecular formula: C20H34O5. Mole weight: 354.5.
Prostaglandin H2
Prostaglandin H2 (PGH2), a potent vasoconstrictor, is produced by the conversion of Arachidonic acid (AA). Prostaglandin H2 is asubstrate for the production of Prostaglandins (PGs) and thromboxanes (TXs) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGH2. CAS No. 42935-17-1. Pack Sizes: 10 μg (283.71 μM * 100 μL in Acetone); 50 μg (283.71 μM * 500 μL in Acetone); 100 μg (283.71 μM * 1 mL in Acetone). Product ID: HY-136500.
Prostaglandin I2, Sodium Salt (PGI2, Prostacyclin)
Potent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Exhibits cytoprotective and fibrinolytic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Prostaglandin I3 sodium salt
PGI3 is a metabolite of EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to Δ17-6-keto PGF1&alpha. Synonyms: PGI3; 6,9alpha-Epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E,17Z-trien1-oic acid sodium salt. Grades: ≥99%. CAS No. 68324-96-9. Molecular formula: C20H29O5·Na. Mole weight: 372.4.
Prostaglandin impurity D
An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Grades: > 95%. Molecular formula: C20H34O5. Mole weight: 354.49.
Prostaglandin impurity F
An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Grades: > 95%. Molecular formula: C20H34O5. Mole weight: 354.49.
Prostaglandin impurity H
An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Grades: > 95%. Molecular formula: C20H32O5. Mole weight: 352.48.
Prostaglandin impurity I
An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Grades: > 95%. Molecular formula: C22H38O5. Mole weight: 382.55.
Prostaglandin Impurity J
An impurities of Prostaglandin E1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Grades: > 95%. Molecular formula: C23H40O5. Mole weight: 396.57.
prostaglandin-I synthase
A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2 into prostaglandin I2 (prostacyclin). Group: Enzymes. Synonyms: prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Enzyme Commission Number: EC 5.3.99.4. CAS No. 65802-86-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5512; prostaglandin-I synthase; EC 5.3.99.4; 65802-86-0; prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Cat No: EXWM-5512.
Prostaglandin J2
Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with K i s of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC 50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PGJ2. CAS No. 60203-57-8. Pack Sizes: 500 μg (14.95 mM * 100 μL in Methyl acetate). Product ID: HY-113366.
Prostaglandin J2
Prostaglandin J2 (PGJ2) is a metabolite of PGD2, exhibiting antimitotic and antiproliferative effects. It inhibits platelet aggregation with IC50 value of 5-10 nM. Uses: Antineoplastic agents. Synonyms: PGJ2; 9-Deoxy-delta-9-prostaglandin D2; 9-Deoxy-delta-9-pgd2; (Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid. Grades: ≥95%. CAS No. 60203-57-8. Molecular formula: C20H30O4. Mole weight: 334.5.
PROSTAGLANDINS
Heterocyclic Organic Compound. Alternative Names: PROSTAGLANDINS;Einecs 234-237-8. CAS No. 11000-26-3. Catalog: ACM11000263.
prostamide/prostaglandin F2α synthase
The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2&alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. Group: Enzymes. Synonyms: prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Enzyme Commission Number: EC 1.11.1.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0502; prostamide/prostaglandin F2α synthase; EC 1.11.1.20; prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Cat No: EXWM-0502.
Prostanozol
Prostanozol. Group: Biochemicals. Alternative Names: (5a,17b)-17-[(Tetrahydro-2H-pyran-2-yl)oxy]-2'H-androst-2-eno[3,2-c]pyrazole. Grades: Highly Purified. CAS No. 1186001-41-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C25H38N2O2. US Biological Life Sciences.
Worldwide
Prostate Microvascular Endothelial Cells, Human (Frozen)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Prostate Microvascular Endothelial Cells, Human (T-25 flask)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.