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| Product | Description | |
|---|---|---|
| SR-717 lithium | SR-717 is an agonist of stimulator of interferon genes STING for treating cancer. SR-717 demonstrates broad interspecies and interallelic specificity. SR-717 functions as a direct cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING. SR-717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant tissues; and facilitated antigen cross-priming. SR-717 also induced the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR-717 lithium; SR 717 lithium; SR717 lithium. Product Category: Agonists. Appearance: Solid powder. CAS No. 2375421-09-1. Molecular formula: C15H8F2LiN5O3. Mole weight: 351.2. Purity: >98%. IUPACName: lithium 2-(6-(1H-imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate. Canonical SMILES: O=C([O-])C1=CC(F)=C(F)C=C1NC(C2=NN=C(N3C=CN=C3)C=C2)=O.[Li+]. Product ID: ACM2375421091. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SR 7826 | SR 7826 is a potent and selective LIMK inhibitor (IC50 = 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). SR 7826 was shown to inhibit cofilin phosphorylation in A7r5 cells and suppress migration and invasion of PC-3 cells in vitro. Synonyms: SR7826; SR-7826; SR 7826; N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea; 1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-1-phenylurea. Grades: ≥98% by HPLC. CAS No. 1219728-20-7. Molecular formula: C22H21N5O2. Mole weight: 387.43. |  |
| SR8278 | SR8278 is a REV-ERBα antagonist and inhibits the REV-ERBα transcriptional repression activity with an EC 50 of 0.47 μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm. SR8278 also can be used for the research of Duchenne muscular dystrophy and Alzheimer's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254944-66-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14415. |  |
| SR 8278 | SR 8278. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 1254944-66-5. Pack Sizes: 10mg. Molecular Formula: C18H19NO3S2, Molecular Weight: 361.48. US Biological Life Sciences. |  Worldwide |
| SR 8278 | SR 8278 is a nuclear heme receptor Rev-Erbα antagonist. This compound inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. SR 8278 increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells. Synonyms: SR8278; SR 8278; SR-8278. 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester; ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 1254944-66-5. Molecular formula: C18H19NO3S2. Mole weight: 361.48. | |
| SR9009 | SR9009 is a REV-ERBα/β agonist with IC 50 s of 670 nM and 800 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16989. | |
| SR9011 | SR9011 is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-29-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988. | |
| SR9011 | SR9011, a synthetic REV-ERB agonist, has been found to have probable effect against sleep disorders and metabolic diseases. IC50: 790 nM and 560 nM for Rev-ErbBα and Rev-ErbBβ respectively. Synonyms: SR 9011; SR-9011; 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-. Grades: 98%. CAS No. 1379686-29-9. Molecular formula: C23H31ClN4O3S. Mole weight: 479.04. | |
| SR9011 hydrochloride | SR9011 hydrochloride is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988A. | |
| SR 9186 | SR 9186 is an inhibitor of the cytochrome P450 isoform CYP3A4 with IC50 value of 0.011 μM. Synonyms: 1-[4-(4-Cyanophenyl)phenyl]-3-[4-(1H-imidazo[4,5-b]pyridin-7-yl)phenyl]urea. Grades: ≥95%. CAS No. 1361414-26-7. Molecular formula: C26H18N6O. Mole weight: 430.5. | |
| SR 9238 | SR 9238 is a potent and selective LXR inverse agonist (IC50 = 43 and 214 nM for LXRβ and LXRα, respectively) with selectivity over a panel of 20 other nuclear receptors, including FXR. SR 9238 exhibits little activity at peripheral LXR. SR 9238 has been shown to reduce hepatic steatosis in obese mice. Synonyms: SR9238; SR 9238; SR-9238; Ethyl 5-[[[[3'- (Methylsulfonyl) [1, 1'-biphenyl]-4-yl]methyl][ (2, 4, 6-trimethylphenyl) sulfonyl]amino]methyl]-2-furancarboxylate. Grades: ≥98% by HPLC. CAS No. 1416153-62-2. Molecular formula: C31H33NO7S2. Mole weight: 595.73. | |
| SR9243 | SR9243 is a potent and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. Synonyms: SR9243; SR-9243; SR 9243. Grades: 98%. CAS No. 1613028-81-1. Molecular formula: C31H32BrNO4S2. Mole weight: 626.62. | |
| SR95531 (Gabazine, GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531) | A selective, competitive antagonist of GABAA receptor (IC50 = 440nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100uM). Also shown to block glycine receptors, but with low affinity (Kb = 190uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 104104-50-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 95531 hydrobromide | SR 95531 hydrobromide is a competitive GABAA receptor antagonist. SR 95531 differs from bicuculline that it selectively antagonizes GABA-induced Cl- currents but exhibits little action on pentobarbitone-induced currents. SR 95531 also acts as a low affinity glycine receptor antagonist. Uses: Gaba antagonists. Synonyms: SR 95531 hydrobromide; SR95531 hydrobromide; SR-95531 hydrobromide; 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid hydrobromide; 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide; Gabazine hydrobromide. Grades: ≥98% by HPLC. CAS No. 104104-50-9. Molecular formula: C15H17N3O3.HBr. Mole weight: 368.23. | |
| SR 95531 hydrobromide | SR 95531 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 104104-50-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SRC-3-IN-2 | SRC-3-IN-2 (SI-12 6c)is an orally active steroid receptor coactivator 3 ( SRC-3 ) inhibitor. SRC-3-IN-2 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3074959-44-4. Pack Sizes: 1 mg. Product ID: HY-163469. | |
| Src I1 | Src I1 is a dual site inhibitor that competes at both the ATP and peptide binding sites of Src tyrosine kinase (IC50 = 44 and 88 nM for Src and Lck, respectively). Src I1 was reported to inhibit VEGFR2 and c-fms at higher concentrations (IC50 = 0.32 and 30 μM, respectively). Synonyms: Src I1; Src I-1; SrcI1. 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine; Src Kinase Inhibitor I; Src Inhibitor 1; Src Inhibitor-1. Grades: ≥99% by HPLC. CAS No. 179248-59-0. Molecular formula: C22H19N3O3. Mole weight: 373.4. | |
| Src I1 | Src I1. Group: Biochemicals. Grades: Purified. CAS No. 179248-59-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SRF-DE | SRF-DE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ChromoionophoreXIII,Semiphthorhodafluordecylester,DZ-49,7-[2-(Decyloxycarbonyl)-phenyl]-10-diethylamino-3-hydroxy-benzo[c]xanthyliumperchlorate. Product Category: Other Fluorophores. Appearance: Deep red powder. CAS No. 135656-96-1. Molecular formula: C38H44NO4·ClO4. Mole weight: 678.2. Purity: 95%+. IUPACName: [7-(2-decoxycarbonylphenyl)-3-hydroxybenzo[c]xanthen-10-ylidene]-diethylazanium;perchlorate. Canonical SMILES: CCCCCCCCCCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](CC)CC)C=C3OC4=C2C=CC5=C4C=CC(=C5)O.[O-]Cl(=O)(=O)=O. Product ID: ACM135656961-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Sridevi. | |
| SRI-011381 | SRI-011381 is an activator of TGF-β signaling. Synonyms: N'-Cyclohexyl-N-(Phenylmethyl)-N-(4-Piperidinylmethyl)-Urea; SRI011381; SCHEMBL16099597; BCP30372; EX-A3008. Grades: 98%. CAS No. 1629138-41-5. Molecular formula: C20H31N3O. Mole weight: 329.5. | |
| SRI-37330 free base | SRI-37330 is a novel inhibitor of TXNIP expression, decreasing glucagon secretion and action and blocking hepatic glucose output, reversing obesity- and STZ-induced diabetes and hepatic steatosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SRI-37330 free base; SRI37330 free base, SRI 37330 free base. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2322245-42-9. Molecular formula: C16H19F3N4O2S. Mole weight: 388.41. Purity: >98%. IUPACName: N-((1-(6-(trifluoromethyl)quinazolin-4-yl)piperidin-3-yl)methyl)methanesulfonamide. Canonical SMILES: CS(=O)(NCC1CN(C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)CCC1)=O. Product ID: ACM2322245429. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-ribosylhomocysteine lyase | Contains Fe2+. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density. Group: Enzymes. Synonyms: S-ribosylhomocysteinase; LuxS. Enzyme Commission Number: EC 4.4.1.21. CAS No. 37288-63-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5323; S-ribosylhomocysteine lyase; EC 4.4.1.21; 37288-63-4; S-ribosylhomocysteinase; LuxS. Cat No: EXWM-5323. |  |
| SR isomer of clemastine fumarate | SR isomer of clemastine fumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61826-32-2. Molecular Formula: C25H30ClNO5. Mole Weight: 459.97. Catalog: APB61826322. |  |
| S, R-Isovalganciclovir Impurity | S, R-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (R,S)-Iso Valganciclovir; (R)-[(S)-3-[(2-Amino-6-oxo-1,6-dihydropurin-9-yl)methoxy)-2-hydroxypropyl)-2,3-dimethylbutanoate. Grades: > 95%. CAS No. 1356932-18-7. Molecular formula: C14H22N6O5. Mole weight: 354.36. | |
| S- (+)-Rolipram | S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer. Synonyms: (S)-(+)-rolipram; 85416-73-5; S-(+)-Rolipram(S)-ROLIPRAMS- (+)-Rolipram. Grades: >98%. CAS No. 85416-73-5. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| Srpin340 | Srpin340 is an isonicotinamide compound that inhibits SRPK1 (Ki = 0.89 μM). It is about 10-fold less effective against SRPK2 and does not inhibit the related SRPKs, Clk1 and Clk4. Srpin340 suppresses the propagation of Sindbis virus in Vero cells and the replication of hepatitis C virus in Huh7/Rep-Feo-2a cells. Synonyms: SRPIN-340; SRPIN 340. Grades: 99.82%. CAS No. 218156-96-8. Molecular formula: C18H18F3N3O. Mole weight: 349.35. | |
| SRPIN340 | SRPIN340. Group: Biochemicals. Grades: Purified. CAS No. 218156-96-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SRPK Inhibitor, SRPIN340 (N- (2-Piperidin-1-yl-5- (trifluoromethyl) phenyl) isonicotinamide, Serine-Arginine-Rich Protein Kinase Inhibitor, SR Protein Kinase Inhibitor, SR Protein Phosphorylation Inhibitor 340, (SRPIN)340) | A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8uM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases. Shown to effectively counteract IGF-1-induced anti-angiogenic to pro-angiogenic VEGF isoforms switch both in cultures in vitro (1h 10uM SRPIN340 prior to 12h IGF-1 stimulation of PCIPs) and in a murine hypoxia-induced retinal neovascularization model in vivo (10pmol/uL/eye intraocular SRPIN340 injection) by inhibiting PKC/SRPK signaling-dependent, alternate splicing factor ASF- (SF2; splicing factor 2) mediated VEGF pro-mRNA PSS (proximal splice site) selection. Suppresses RNA virus Sindbis propagation (IC50 = 60uM in Vero cultures) and HCV-JFH1 replication (1 & 10uM SRPIN340 in Huh7.5.1 cultures). Exhibits no toxicity toward rats (2g/kg p.o. for 2 wks), CHO (5mg/ml for 24h), or Huh7 (30uM for 48h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SRS11-92 | SRS11-92 is an effective iron death inhibitor. It inhibits Erastin-induced iron death cells in HT-1080 human fibrosarcoma cells (EC50=6 nM). Synonyms: 4-(Cyclohexylamino)-3-[(Phenylmethyl)Amino]-Benzoic acid, Ethylester. Grades: 98%. CAS No. 1467047-25-1. Molecular formula: C22H28N2O2. Mole weight: 352.5. | |
| SRT1720 | SRT1720 is a drug developed by Sirtris Pharmaceuticals intended as a small-molecule activator of the sirtuin subtype SIRT1. It has similar activity in the body to the known SIRT1 activator resveratrol, but is 1000x more potent. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. Although SRT1720 is not currently undergoing clinical development, a related compound, SRT2104, is currently in clinical development for metabolic diseases. Synonyms: 2-Quinoxalinecarboxamide, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-; N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide; SRT 1720; SRT-1720. Grades: ≥95%. CAS No. 925434-55-5. Molecular formula: C25H23N7OS. Mole weight: 469.56. | |
| SRT1720 | SRT1720 Inhibitor. Uses: Scientific use. Product Category: T2412. CAS No. 1001645-58-4. |  |
| SRT 1720 | SRT 1720 is a selective activator of human SIRT1 with an EC 1.5 of 0.16 μM, and shows less potent activities for SIRT2 and SIRT3 with EC 1.5 s of 37 μM and > 300 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 925434-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10532. | |
| SRT 1720 dihydrochloride | SRT 1720 dihydrochloride is a selective and orally active activator of SIRT1 with an EC 50 of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2468639-77-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15145A. | |
| SRT1720 hydrochloride | SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3. Synonyms: SRT1720 HCl; SRT1720; N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide hydrochloride. Grades: >98%. CAS No. 1001645-58-4. Molecular formula: C25H23N7OS.HCl. Mole weight: 506.02. | |
| SRT1720 Hydrochloride | SRT1720 Hydrochloride. Group: Biochemicals. Alternative Names: N-[2-[3- (1-piperazinylmethyl) imidazo[2, 1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 1001645-58-4. Pack Sizes: 5mg. Molecular Formula: C25H23N7OS xHCl, Molecular Weight: 469.56. US Biological Life Sciences. | Worldwide |
| SRT2104 (GSK2245840) | SRT2104 (GSK2245840) is a selective SIRT1 activator involved in the regulation of energy homeostasis. Phase 2. Synonyms: SRT2104; SRT 2104; SRT-2104; GSK2245840; GSK-2245840; GSK 2245840. Grades: >98%. CAS No. 1093403-33-8. Molecular formula: C26H24N6O2S2. Mole weight: 516.64. | |
| SRT2183 | SRT2183 is a Sirt1 activator, currently being developed by Sirtris Pharmaceuticals. SRT2183 has similar activity in the body to another SIRT1 activator SRT1720, but is closer in potency to resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. Synonyms: SRT 2183; SRT-2183; (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide. Grades: 98%. CAS No. 1001908-89-9. Molecular formula: C27H24N4O2S. Mole weight: 468.575. | |
| SRT3025 HCl | SRT3025 HCl is the hydrochloride form of SRT3025, an agonist of Sirt1. In Fanconi anemia mice, SRT3025 expands hematopoietic stem and progenitor cells as well as improves hematopoiesis; In Apoe-/- mice, SRT3025 decreases plasma cholesterol, inflammation, atherosclerosis, and also increases hepatic Ldlr expression and Pcsk9 accumulation; SRT3025 suppresses the growth of Panc-1 xenografts. Synonyms: SRT3025 HCl; SRT 3025 HCl; SRT-3025 HCl. Grades: 99.62 %. CAS No. 2070015-26-6. Molecular formula: C31H31N5O2S2.HCl. Mole weight: 606.2. | |
| SRT3109 | SRT3109 is a CXCR2 ligand. Synonyms: SRT3109; SRT-3109; SRT 3109. N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide; SCHEMBL3180319; ABP000357; ZINC68197865; CS-0977; RL-00854; HY-15462; DB-061750; KB-298382; CS 0977; RL 00854; HY 15462; DB 061750; KB 298382; CS0977; RL00854; HY15462; DB061750; KB298382. CAS No. 1204707-71-0. Molecular formula: C18H23F2N5O4S2. Mole weight: 475.53. | |
| SRT3190 | SRT3190 is a CXCR2 ligand. Synonyms: SRT3190; SRT-3190; SRT 3190. SCHEMBL3171248; QVKPEMXUBULFBM-FZMZJTMJSA-N ; 4065AH; ZINC95641942; CS-0265; HY-13021; KB-80727; W-5813; CS 0265; HY 13021; KB 80727; W 5813; CS0265; HY13021; KB80727; W5813; N-(2-((2,3-Difluorobenzyl)thio)-6-(((2S,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide. CAS No. 1204707-73-2. Molecular formula: C18H23F2N5O4S2. Mole weight: 475.53. | |
| SS-208 | SS-208 is a selective HDAC6 inhibitor, with an IC 50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVS100. CAS No. 2245942-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126330. | |
| SS-228Y | SS-228Y is an antibiotic produced by Chainia Sp. It is active against gram-positive bacteria and Ehrlich's ascites carcinoma. Synonyms: Antibiotic SS-228 Y; SS-228 Y. Grades: 95%. CAS No. 56257-16-0. Molecular formula: C19H14O6. Mole weight: 338.31. | |
| SS5020 | SS5020 is a novel benzopyran antiestrogen and it exhibits no genotoxic activity to damage DNA. In addiction, SS5020 does not present significant uterotrophic potential in rats. SS5020 had stronger antitumor potential than those same antiestrogens against 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats when using the human equivalent molar dose of TAM. Uses: Antitumor activity. Synonyms: SS5020; SS5020; SS 5020. (E)-3-(4-((7-hydroxy-2-oxo-3-phenyl-2H-chromen-4-yl)methyl)phenyl)acrylic acid. Grades: 98%. CAS No. 1334310-70-1. Molecular formula: C25H18O5. Mole weight: 398.41. | |
| SS-56C | SS-56C is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 C. CAS No. 39471-55-1. Molecular formula: C19H35N3O14. Mole weight: 529.5. | |
| SS-56D | SS-56D is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 D. Molecular formula: C19H35N3O13. Mole weight: 513.49. | |
| SSA protein SS-56 (55-64) | A peptide fragment of SSA protein SS-56. | |
| S,S-Atorvastatin | . Uses: Anticholesteremic agents; hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: (1betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-, (R*,R*)-. CAS No. 110862-48-1. Molecular formula: C33H35FN2O5. Mole weight: 558.65. | |
| S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE | S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE. Product Category: Heterocyclic Organic Compound. CAS No. 119784-44-0. Molecular formula: C9H8S4. Mole weight: 244.42. Product ID: ACM119784440. Alfa Chemistry ISO 9001:2015 Certified. | |
| SSBR | SSBR. Group: Polymers. |  |
| S-Scoulerine | S-Scoulerine. Group: Biochemicals. Alternative Names: 5, 8, 13, 13a-Tetrahydro-3, 10-dimethoxy-6H-dibenzo[a, g]quinolizine-2, 9-diol; (+/-)-3,10-Dimethoxy-berbine-2,9-diol; (RS)-scoulerine. Grades: Highly Purified. CAS No. 6451-73-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C19H21NO4. US Biological Life Sciences. | Worldwide |
| S,S'-Diethyl Dithiocarbonate | S,S'-Diethyl Dithiocarbonate. Group: Biochemicals. Alternative Names: Dithiocarbonic Acid S,S'-Diethyl Ester. Grades: Highly Purified. CAS No. 623-80-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| s,s'-Diethyl N,N'-hexane-1,6-diylbis(dibutylethylammonium)disulfate | s,s'-Diethyl N,N'-hexane-1,6-diylbis(dibutylethylammonium)disulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tetrabutyldiethylhexamethylenediammonium ethylsulfate. Product Category: Heterocyclic Organic Compound. CAS No. 68052-49-3. Molecular formula: C26H58N2.2C2H5O4S. Mole weight: 648.999520 [g/mol]. Purity: 0.96. IUPACName: dibutyl-[6-[dibutyl(ethyl)azaniumyl]hexyl]-ethylazanium; ethyl sulfate. Canonical SMILES: CCCC[N+](CC)(CCCC)CCCCCC[N+](CC)(CCCC)CCCC.CCOS(=O)(=O)[O-].CCOS(=O)(=O)[O-]. ECNumber: 268-327-3. Product ID: ACM68052493. Alfa Chemistry ISO 9001:2015 Certified. | |
| S,S'-dimethyl dithiocarbonate | S,S'-dimethyl dithiocarbonate. Group: Biochemicals. Grades: Highly Purified. CAS No. 868-84-8. Pack Sizes: 500g, 1kg. Molecular Formula: C3H6OS2. US Biological Life Sciences. | Worldwide |
| S,S-Diphenylsulfilimine Monohydrate | S,S-Diphenylsulfilimine Monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 68837-61-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| SSE15206 | SSE15206 is a tubulin polymerization inhibitor that overcomes multidrug resistance. It exhibits potent antiproliferative activities in cancer cell lines. Synonyms: HY-111425; SSE-15206; SSE 15206; 5-Phenyl-3-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrazole-2-carbothioamide. CAS No. 1370046-40-4. Molecular formula: C19H21N3O3S. Mole weight: 371.45. | |
| Sse9 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of pBR322 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. ↑AATT TTAA&darr. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sse9 I gene from Sporosarcina species. Pack: 10 mM Tis-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1180RE. | |
| SSEA-4 hexaose | SSEA-4 Hexaose is an extraordinary compound origining from the SSEA-4 antigen, used for studying diverse ailments, encompassing the realms of cancer to neurodegenerative disorders. Synonyms: Neu5Aca2-3Galb1-3GalNAcb1-3Gala1-4Galb1-4Glc; Stage-Specific Embryonic Antigen-4. Molecular formula: C43H71N2O34Na. Mole weight: 1183.01. | |
| S, S'-Ethylenebis (glutathione) | S, S'-Ethylenebis (glutathione) is a haloethane-glutathione conjugate formed via GSH transferases. S, S'-Ethylenebis (glutathione) formation is used to study the polymorphism in glutathione conjugation activity of human erythrocytes towards ethylene dibromide. Group: Biochemicals. Alternative Names: 2,2'-(1,2-Ethanediyl)bis[L-γ-glutamyl-L-cysteinylglycine. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| SSI-4 | SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11 C, used as a ligand to in vivo small animal PET/CT imaging of SCD1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1875084-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155033. | |
| SS isomer of clemastine fumarate | SS isomer of clemastine fumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61826-29-7. Molecular Formula: C25H30ClNO5. Mole Weight: 459.97. Catalog: APB61826297. | |
| S, S-Isovalganciclovir Impurity | S, S-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (S,S)-Iso Valganciclovir Hydrochloride; (2S)-3-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-L-valine 2-Hydroxypropyl Ester Hydrochloride. Grades: > 95%. CAS No. 1401562-13-7. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83. | |
| SSM 3 trifluoroacetate | SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM) which blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro. Synonyms: SSM 3 trifluoroacetate; SSM3 trifluoroacetate; SSM-3 trifluoroacetate; SSM3 TFA; SSM-3 TFA; SSM 3 TFA; SSM3 TFA salt; rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt. Grades: ≥98% by HPLC. CAS No. 922732-52-3. Molecular formula: C22H32N12O2.4CF3CO2H. Mole weight: 952.66. | |
| Ssp I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. AAT↑ATT TTA↓TAA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer K, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene SspI from Sphaerotilus species. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1181RE. | |
| SSR125543 | SSR125543 is a selective corticotropin-releasing factor 1 receptor (CRF1) antagonist with pKi value of 9.08 for native CRF1 receptor. It can prevent stress-induced cognitive deficit associated with hippocampal dysfunction. In Apr 2011, Phase-II for Major depressive disorder was discontinued. Uses: Major depressive disorder. Synonyms: SSR125543; SSR 125543; SSR-125543; SSR 125543A;321839-75-2(hydrochloride);(S)-4-(2-chloro-4-methoxy-5-methylphenyl)-N-(2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl)-5-methyl-N-(prop-2-yn-1-yl)thiazol-2-amine. Grades: 98%. CAS No. 752253-39-7. Molecular formula: C27H28ClFN2OS. Mole weight: 483.04. | |
| SSR 125543A | SSR 125543A is a potent and orally bioactive corticotropin-releasing factor 1 receptor (CRF1) antagonist (pKi values of 8.73 and 9.08 for human cloned or native CRF1 receptors, respectively) with 1000-fold selectivity for CRF1 over CRF2α receptor and CRF binding protein. SSR 125543A exhibited antidepressant and anxiolytic properties in the Flinders Sensitive Line rats. Synonyms: SR-125543A; SR125543A; LS-150601; LS150601; LS 150601; 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine hydrochloride. Grades: 98%. CAS No. 321839-75-2. Molecular formula: C27H28ClFN2OS.HCl. Mole weight: 519.5. | |
| SSR128129E | SSR128129E is an orally available and allosteric FGFR inhibitor with an IC 50 of 1.9 μM for FGFR1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SSR. CAS No. 848318-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15599. | |
| SSR128129E | SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR) signaling by binding to the extracellular FGFR domain without affecting orthosteric FGF binding. SSR128129E exhibits allosteric properties, including probe dependence, signaling bias, and ceiling effects. Oral delivery of SSR128129E inhibits arthritis and tumors that are relatively refractory to anti-vascular endothelial growth factor receptor-2 antibodies. Thus, orally-active extracellularly acting small-molecule modulators of RTKs with allosteric properties can be developed and may offer opportunities to improve anticancer treatment. Synonyms: SSR128129E; SSR 128129E; SSR-128129E. Grades: 0.98. CAS No. 848318-25-2. Molecular formula: C18H15N2NaO4. Mole weight: 346.318. | |
| SSR128129E free acid | SSR128129E free acid is a multi-FGFR blocker with allosteric properties. It inhibits FGFR signaling by binding to the extracellular FGFR domain without affecting orthosteric FGF binding. Synonyms: SSR free acid. Grades: >98%. CAS No. 848463-13-8. Molecular formula: C18H16N2O4. Mole weight: 324.33. | |
| SSR 146977 hydrochloride | SSR 146977 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 264618-38-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SSR 146977 hydrochloride | SSR 146977 hydrochloride is a potent and selective NK3 receptor antagonist (Ki = 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor, respectively). SSR 146977 also exhibits an inhibitory effect on senktide-induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). Synonyms: SSR 146977 hydrochloride; SSR146977 hydrochloride; SSR-146977 hydrochloride; N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-piperidinyl]-N,N-dimethylurea hydrochloride. Grades: ≥98% by HPLC. CAS No. 264618-38-4. Molecular formula: C35H42Cl2N4O2.HCl. Mole weight: 658.11. | |
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