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| Product | Description | |
|---|---|---|
| Spiro-MeOTAD | This product is an enabling product used as a Hole Transport Material for high-performance solar cells and thus has been enhanced for energy efficiency. Uses: High-mobility material used for white oleds to increase hole injection and transport. it is the best solid-state hole transporting material, to date, used to replace the liquid electrolyte for dssc solar cells, due to an excellent pore-filling property in nanoporous tio2 film with pore size of around 30-50 nm; attributed to its small molecular size. Group: Organic light-emitting diode (oled) materials. Alternative Names: N2,N2,N2',N2',N7,N7,N7',N7'-octakis(4-methoxyphenyl)-9,9'-spirobi[9H-fluorene]-2,2',7,7'-tetramine,Spiro-OMeTAD. CAS No. 207739-72-8. Pack Sizes: 1, 5 g in glass bottle. Product ID: 2,2,7,7-tetrakis(N,N-di-p-methoxyphenyl-amine)-9,9-spirobifluorene. Molecular formula: 1225.43. Mole weight: C81H68N4O8. COC (C=C1)=CC=C1N (C2=CC=C (C=C2)OC)C (C=C3)=CC4=C3C (C=CC (N (C5=CC=C (C=C5)OC)C6=CC=C (C=C6)OC)=C7)=C7C84C9=C (C=CC (N (C%10=CC=C (C=C%10)OC)C%11=CC=C (C=C%11)OC)=C9)C%12=C8C=C (N (C%13=CC=C (C=C%13)OC)C%14=CC=C (C=C%14)OC)C=C%12. InChI=1S/C81H68N4O8/c1-86-65-29-9-53 (10-30-65) 82 (54-11-31-66 (87-2) 32-12-54) 61-25-45-73-74-46-26-62 (83 (55-13-33-67 (88-3) 34-14-55) 56-15-35-68 (89-4) 36-16-56) 50-78 (74) 81 (77 (73) 49-61) 79-51-63 (84 (57-17-37-69 (90-5) 38-18-57) 58-19-39-70 (91-6) 40-20-58) 27-47-75 (79) 76-48-28-64 (52-80 (76) 81) 85 (59-21-41-71 |  |
| Spiro-MeOTAD-HTM1 | Spiro-MeOTAD-HTM1. Uses: Designed for use in research and industrial production. Product Category: Dye-Sensitized Solar Cell (DSSC). CAS No. 1573202-31-9. Product ID: ACM1573202319. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Spiromesifen | Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase , and has no cross-resistance to any resistant mite or whitefly populations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSN 2060. CAS No. 283594-90-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-114591. |  |
| Spiromesifen | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. Alternative Names: Forbid, BSN 2060, Oberon,Butanoic acid, 3,3-dimethyl-, 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl ester, Spiromesifen. |  |
| Spiromesifen Metabolite M01 | It is the metabolite of Spiromesifen, which is a spirocyclic tetronic acid, environmentally friendly and novel structural pesticide. Synonyms: 1-Oxaspiro[4.4]non-3-en-2-one, 4-hydroxy-3-(2,4,6-trimethylphenyl)-; 3-Mesityl-2-oxo-1-oxaspiro(4.4)non-3-en-4-ol; Spiromesifen-alcohol; 4-Hydroxy-3-mesityl-1-oxaspiro(4.4)non-3-en-2-one. Grades: ≥90%. CAS No. 148476-30-6. Molecular formula: C17H20O3. Mole weight: 272.34. |  |
| Spiromesifen Metabolite M01 | analytical standard. Group: Pesticides & metabolites standards. | |
| Spiro-mTTB | Spiro-mTTB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,2',7,7'-Octa(m-tolylamine)-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 302344-41-8. Molecular formula: C81H68N4. Mole weight: 1097.43 g/mol. Product ID: ACM302344418. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spironolactone | Spironolactone is a synthetic, 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Alternative Names: 7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone; 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone; SC-9420; Adactone. Grades: Highly Purified. CAS No. 52-01-7. Pack Sizes: 50g, 100g. Molecular Formula: C??H??O?S, Molecular Weight: 416.57. US Biological Life Sciences. |  Worldwide |
| Spironolactone | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H32O4S. CAS No. 52-01-7. Prepack ID 49631028-5g. Molecular Weight 416.57. See USA prepack pricing. |  |
| Spironolactone | Spironolactone is an aldosterone antagonist that acts on the aldosterone mineralocorticoid receptor ( IC 50 =24 nM) and androgen receptor ( IC 50 =77 nM), promotes podocyte autophagy and regulates pain. Spironolactone improves hypertension-related vascular hypertrophy and remodeling by reducing angiotensin II (Ang?)-induced inflammation, reduces aldosterone-induced vascular and soft tissue calcification through PIT1-dependent signaling, and alleviates vascular dysfunction in type ? diabetic mice by reducing oxidative stress and restoring NO/GC signaling; at low concentrations, it and its metabolites can interfere with aldosterone biosynthesis in the adrenal cortex and inhibit voltage-dependent Ca 2+ channels to exert antihypertensive effects [1] [2] [3] [4] [5] [6] [7] [8] [9] [10]. Uses: Scientific research. Group: Natural products. Alternative Names: SC9420. CAS No. 52-01-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-B0561. | |
| Spironolactone acid | An impurity of Spironolactone Spironolactone is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Grades: > 95%. Molecular formula: C24H34O5S. Mole weight: 434.60. | |
| Spironolactone-d3 ((7a,7a)-7-(Acetylthyo-d3)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid g-Lactone,. 7a-Acetylthio-d3-3-oxo-17a-pregn-4-ene-21,17-carbolactone, SC-9420-d3) | t is a synthetic 17-lac. Group: Biochemicals. Alternative Names: (7a,7a)-7-(Acetylthyo-d3)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid g-Lactone; 7a-Acetylthio-d3-3-oxo-17a-pregn-4-ene-21,17-carbolactone; SC-9420-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Spironolactone EP Impurity 11 | Spironolactone EP Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132152-57-9. Molecular formula: C18H22O3. Mole weight: 286.37. Catalog: APB132152579. | |
| Spironolactone EP Impurity A | Spironolactone EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132458-33-4. Molecular formula: C24H30O4S. Mole weight: 414.56. Catalog: APB132458334. | |
| Spironolactone EP Impurity A (Delta-20-Spironolactone) | an impurity of Spironolactone. Synonyms: (7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxo-pregna-4,20-diene-21-carboxylic Acid γ-Lactone; spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan] Pregna-4,20-diene-21-carboxylic Acid Deriv. Grades: > 95%. CAS No. 132458-33-4. Molecular formula: C24H30O4S. Mole weight: 414.57. | |
| Spironolactone EP Impurity C | an intermediate in the synthesis of Canrenone. Synonyms: 6,7-Dihydrocanrenone; 17-Hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic Acid γ-Lactone; 17β-Hydroxy-3-oxopregn-4-en-21-carboxylic Acid γ-Lactone; 3-(3-Oxo-17β-hydroxy-4-androsten-17-yl)propionic Acid γ-Lactone; 3-(3-Oxo-17β-hydroxyandrost-4-en-17α-yl)propiol. Grades: > 95%. CAS No. 976-70-5. Molecular formula: C22H30O3. Mole weight: 342.48. | |
| Spironolactone EP Impurity I | An impurity of Spironolactone Spironolactone is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Synonyms: 7α-Acetylthio-17α-ethoxymethy Testosterone. Grades: > 95%. Molecular formula: C24H36O4S. Mole weight: 420.61. | |
| Spironolactone Impurity B | An impurity of Spironolactone Spironolactone is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Synonyms: 4-Bromo-spironolactone. Grades: > 95%. Molecular formula: C24H31BrO4S. Mole weight: 495.48. | |
| Spironolactone Impurity G | An impurity of Spironolactone Spironolactone is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Synonyms: Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-6,17-dihydroxy-3-oxo-,g-lactone, (6b,7a,17a)-. Grades: > 95%. CAS No. 880106-10-5. Molecular formula: C24H32O5S. Mole weight: 432.58. | |
| Spironolactone Impurity H | Cas No. 55706-91-7. | |
| Spironolactone Related Compound | an impurity of Spironolactone. Synonyms: S-[17-Alfa-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7-alfa-yl] Ethanethioate; 7β-Acetylthio-17α-ethoxymethy Testosterone; Spironolactone EP Impurity I. Grades: > 95%. Molecular formula: C24H36O4S. Mole weight: 420.62. | |
| Spironolactone (Standard) | Spironolactone (Standard) is the analytical standard of Spironolactone. This product is intended for research and analytical applications. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC 50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC 50 of 77 nM. Spironolactone promotes autophagy in podocytes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC9420 (Standard). CAS No. 52-01-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0561R. | |
| Spiro-NPB | Spiro-NPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N'-Bis(naphthalen-1-yl)-N,N'-bis(phenyl)-2,7-diamino-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 932739-76-9. Molecular formula: C57H38N2. Mole weight: 750.93 g/mol. Purity: 95%+. IUPACName: 2-N',7-N'-dinaphthalen-1-yl-2-N',7-N'-diphenyl-9,9'-spirobi[fluorene]-2',7'-diamine. Canonical SMILES: C1=CC=C(C=C1)N(C2=CC3=C(C=C2)C4=C(C35C6=CC=CC=C6C7=CC=CC=C57)C=C(C=C4)N(C8=CC=CC=C8)C9=CC=CC1=CC=CC=C19)C1=CC=CC2=CC=CC=C21. Density: 1.35 g/ml. Product ID: ACM932739769. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spiro-Oxanthromicin A | Spiro-Oxanthromicin A is a polyketide first isolated from a soil-derived Streptomyces sp. Spiro-Oxanthromicin A inhibits mislocalisation of the oncogenic mutant K-Ras from the plasma membrane of intact Madin-Darby canine kidney (MDCK) cells. It inhibits Bacillus cereus but has no activity against HSV-1, Mycobacterium tuberculosis H37Ra and phytopathogenic fungi. Synonyms: Oxanthromicin A, spiro; (±)-spiro-oxanthromicin A; 2',7'-dihydro-2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-spiro[anthracene-9(10H),3'-[3H]benz[de]anthracene]-3,9'-dicarboxylic acid; 2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-2',7'-dihydro-10H-spiro[anthracene-9,3'-benzo[de]anthracene]-3,9'-dicarboxylic acid. Grades: ≥95% by HPLC. CAS No. 1616622-10-6. Molecular formula: C36H26O10. Mole weight: 618.58. | |
| Spiro-Pye | Spiro-Pye. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Dipyrenyl-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 886456-80-0. Molecular formula: C57H32. Mole weight: 716.86 g/mol. Product ID: ACM886456800. Alfa Chemistry ISO 9001:2015 Certified. Categories: Spiropyran. | |
| Spirosendan | Spirosendan, a new skeletal limonoid prossessing a spiro-structure, was isolated from the root bark of Melia toosendan (Meliaceae). Synonyms: 2-Butenoic acid, 2-methyl-, (1R, 1'S, 2S, 3'R, 3'aR, 4S, 5S, 5'aR, 6'S, 6'aS, 9'S, 10'aR, 10'bR, 10'cR)-1', 3'-bis(acetyloxy)-4-(3-furanyl)decahydro-5, 6'-dihydroxy-3'a, 5, 10'b-trimethylspiro[cyclopentane-1, 7'-[7H-6a, 9]methano[1H, 4H]furo[2', 3', 4':4, 5]naphtho[2, 1-c]pyran]-2-yl ester, (2E)-; 220137-96-2. Grades: >98%. CAS No. 220137-96-2. Molecular formula: C35H46O11. Mole weight: 642.7. | |
| Spirost-5-en-3-ol,6-methyl-,acetate,(3b,25r)-(9ci) | Spirost-5-en-3-ol,6-methyl-,acetate,(3b,25r)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHYLDIOSGENIN ACETATE, 6-;6A-METHYL-5-SPIROSTEN-3BETA-OL ACETATE;6-METHYLDIOSGENIN ACETATE;5,25R-SPIROSTEN-6-METHYL-3BETA-OL 3-ACETATE;5,20-ALPHA, 22-ALPHA, 25D-SPIROSTEN-6-METHYL-3-BETA-OL ACETATE;(25R)-6-methylspirost-5-en-3beta-ol acetate;(25R)-6-Me. Product Category: Heterocyclic Organic Compound. CAS No. 6877-73-2. Molecular formula: C30H46O4. Mole weight: 470.6838. Density: 1.11 g/cm³. Product ID: ACM6877732. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spiro-TAD | Spiro-TAD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,2',7,7'-Tetrakis(N,N-diphenylamino)-2,7-diamino-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). Appearance: Powder. CAS No. 189363-47-1. Molecular formula: C73H52N4. Mole weight: 985.22 g/mol. Purity: 95%+. IUPACName: 2-N,2-N,2-N',2-N',7-N,7-N,7-N',7-N'-octakis-phenyl-9,9'-spirobi[fluorene]-2,2',7,7'-tetramine. Canonical SMILES: C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=CC4=C(C=C3)C5=C(C46C7=C(C=CC(=C7)N(C8=CC=CC=C8)C9=CC=CC=C9)C1=C6C=C(C=C1)N(C1=CC=CC=C1)C1=CC=CC=C1)C=C(C=C5)N(C1=CC=CC=C1)C1=CC=CC=C1. Density: 1.34 ± 0.1 g/ml. Product ID: ACM189363471. Alfa Chemistry ISO 9001:2015 Certified. Categories: Spiro-Tablinen. | |
| Spirotetramat | Spirotetramat (BY-108330) is a pesticide, that can be used to control aphids on crops, without significant phytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BY-108330. CAS No. 203313-25-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120253. | |
| Spirotetramat | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. Alternative Names: Spirotetramat, Carbonic acid, 3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl ester, cis-, BYI 8330, Kontos,Carbonic acid, cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl ester, Movento, Ultor. | |
| Spirotetramat Metabolite BYI08330-cis-enol | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitesstable isotope labelled compoundspesticides & metabolites. | |
| Spirotetramat Metabolite BYI08330-cis-keto-hydroxy | analytical standard. Group: Pesticides & metabolites standards. | |
| Spirotetramat Metabolite BYI08330 enol-glucoside | analytical standard. Group: Pesticides & metabolites standards. | |
| Spirotetramat Metabolite BYI08330-mono-hydroxy | analytical standard. Group: Pesticides & metabolites standards. | |
| Spiro-TPD | Spiro-TPD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N'-Bis (3-methy lpheny l)-N,N'-bis (pheny l)-2,7-diamino-9,9-spirobif luorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1033035-83-4. Molecular formula: C51H38N2. Mole weight: 678.86 g/mol. Purity: 95%+. IUPACName: 2-N',7-N'-bis(3-methylphenyl)-2-N',7-N'-diphenyl-9,9'-spirobi[fluorene]-2',7'-diamine. Canonical SMILES: CC1=CC(=CC=C1)N(C2=CC=CC=C2)C3=CC4=C(C=C3)C5=C(C46C7=CC=CC=C7C8=CC=CC=C68)C=C(C=C5)N(C9=CC=CC=C9)C1=CC=CC(=C1)C. Density: 1.29 g/ml. Product ID: ACM1033035834. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spirotryprostatin B | It is a mammalian cell cycle inhibitor produced by the strain of Aspergillus fumigatus. 12.5 μg/mL of Spirotryprostatin B can inhibit the G2/M phase of the cell cycle in tsFT210 cells. Synonyms: (3S,3'S,5'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-5a,6,7,8-tetrahydro-3H-dipyrrolo[1,2-c:1',3'-f]pyrazine]-2,5',10'-trione; Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H), 3'-[3H]indole]-2',5,10(1'H)-trione, 5a,6,7,8-tetrahydro-3-(2-methyl-1-propen-1-yl)-, (2S,3S,5aS)-. CAS No. 182234-26-0. Molecular formula: C21H21N3O3. Mole weight: 363.41. | |
| Spiro-TTB | Spiro-TTB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,2',7,7'-Tetra(N,N-di-p-tolyl)amino-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 515834-67-0. Molecular formula: C81H68N4. Mole weight: 1097.43 g/mol. Product ID: ACM515834670. Alfa Chemistry ISO 9001:2015 Certified. Categories: Spiro-Tablinen. | |
| Spiroxamine | Spiroxamine is a fungicide that can be used to kill grapes with less residue [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118134-30-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-121884. | |
| Spiroxamine | Spiroxamine. Group: Biochemicals. Alternative Names: 8-(1,1-Dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-methanamine; Impulse; Impulse. Grades: Highly Purified. CAS No. 118134-30-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C18H35NO2. US Biological Life Sciences. | Worldwide |
| Spiroxatrine | Spiroxatrine is a 5-HT1A antagonist and a potent α2C adrenergic receptor antagonist. Spiroxatrine exhibits great anxiolytic effects in combination with buspirone. Synonyms: 8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one. CAS No. 1054-88-2. Molecular formula: C22H25N3O3. Mole weight: 379.46. | |
| Spiroxatrine | Spiroxatrine. Group: Biochemicals. Grades: Purified. CAS No. 1054-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Spirulina | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Spirulina powder | Spirulina powder. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SPIRULINA POWDER;Spirulina Powder/Teblet;Spirulina Powder S. Product Category: Heterocyclic Organic Compound. CAS No. 724424-92-4. Mole weight: 0. Product ID: ACM724424924. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spirulina Powder | 100g Pack Size. Group: Biochemicals, Diagnostic Raw Materials, Flavours and Fragrance Materials. Formula: N/A. CAS No. 724424-92-4. Prepack ID 89991888-100g. See USA prepack pricing. | |
| Spirulina Powder | Spirulina powder is made from the spirulina, a microscopic blue-green algae in the shape of a perfect spiral coil living both in sea and fresh water. Spirulina powder supplied by yesherb contains high amount of protein, between 55% -77% by dry weight. Spirulina powder is a complete protein, containing all essential amino acids, and rich in essential fatty acids, variety of vitamins and minerals. Group: Others. Spirulina Powder; Spirulina. Cat No: EXTC-121. |  |
| Spirulina Powder | Spirulina Powder. CAS No. 724424-92-4. |  |
| Spisulosine | Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynoma with evidence of preclinical antitumor activity. Phase I clinical trial results: Dose level VIII (200 mg/m(2)) was considered the MTD, and dose level IX (160 mg/m(2)) was defined as the RD. Limited antitumor activity was observed. Synonyms: 1-deoxysphinganine (m18:0); ES-285; ES 285; ES285; 1-deoxy SA; (2S,3R)-2-amino-3-hydroxy-octadecane; (+)-Spisulosine; 3-Octadecanol, 2-amino-, (R-(R*,S*))-; (2S,3R)-2-amino-3-octadecanol; 2S-amino-3R-octadecanol. Grades: >99%. CAS No. 196497-48-0. Molecular formula: C18H39NO. Mole weight: 285.51. | |
| SPK-601 | SPK-601 is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor,a useful antimicrobial agent. Synonyms: LMV-601; LMV601; LM -601; SPK601; SPK-601; SPK 601. Grades: >98%. CAS No. 1096687-52-3. Molecular formula: C11H15KOS2. Mole weight: 266.46. | |
| SPL 334 | SPL 334 is an S-nitrosoglutathione reductase inhibitor that prevents weight loss, and alleviates lung inflammation and fibrosis in a bleomycin injury model of interstitial lung disease in mice. Synonyms: SPL-334; SPL334; SPL 334; 4-[[2-[[(2-Cyanophenyl)methyl]thio]-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 688347-51-5. Molecular formula: C22H15N3O3S2. Mole weight: 433.5. | |
| SPL-334 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| sPLA2-IIA Inhibitor II, KH064 ( (S) -5- (4- (benzyloxy) phenyl) -4- (7-phenylheptanamido) pentanoic Acid, Phospholipase A2 Group IIA Inhibitor II, PLA2g2a Inhibitor II) | A reversible, potent, and selective sPLA2-IIA/PLA2g2a (phospholipase A2 group IIA) inhibitor (IC50 = 29nM) that displays much reduced potency against sPLA2-V/PLA2g5 (PLA2 group V; IC50 = 2uM) and is reported not to affect the activity of cytosolic cPLA2, Ca2+-independent iPLA2, 30 human GPCRs, and 25 other enzymes. In addition to being useful in studying PLA2g2a-mediated cellular responses in cultures in vitro (100% inhibition of LPS-induced PGE2 production in HMC-1 cells; 15 min 10uM pretreatment), KH064 is orally available in rats and efficacious in various rat disease models in vivo (5mg/kg p.o.), including adjuvant-induced arthritis, spontaneous hypertension, high fat diet-induced metabolic disorders. Comparing to the substrate-competitive inhibitor c(2NapA)LS(2NapA)R, KH064 also effectively chelates sPLA2-IIA active site Ca2+ in addition to targeting the enzyme's N-terminal lipid substrate binding site. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| sPLA2 Inhibitor | sPLA2 Inhibitor is an orally active inhibitor of secreted phospholipases A2 IIA (sPLA2-IIA). It exhibits anti-inflammatory effects, and attenuates NF-κB signaling in lung cancer cells and protects against diet-induced metabolic syndrome in rats. Synonyms: KH064; Secretory Phospholipase A2 Inhibitor; (S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid; (4S)-4-(7-phenylheptanoylamino)-5-(4-phenylmethoxyphenyl)pentanoic acid. Grades: ≥95%. CAS No. 393569-31-8. Molecular formula: C31H37NO4. Mole weight: 487.6. | |
| sPLA?-IIA Inhibitor I | The sPLA?-IIA Inhibitor I controls the biological activity of sPLA?-IIA. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| SPL-B | SPL-B is an orally active inhibitor of transforming acidic coiled-coil protein (TACC3) exhibiting an inhibitory effect against the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and tumor growth. Uses: Antitumor agent. Synonyms: 8-[[ethyl(pyridin-4-ylmethyl)amino]methyl]-7-hydroxy-4-(2-oxochromen-3-yl)chromen-2-one. Grades: 98%. CAS No. 1465248-60-5. Molecular formula: C27H22N2O5. Mole weight: 454.47. | |
| Spleen, Bovine | Spleen, Bovine. Group: Biologicals. Grades: Tissue. Pack Sizes: 5Ea. US Biological Life Sciences. | Worldwide |
| spleen exonuclease | Preference for single-stranded substrate. Group: Enzymes. Synonyms: 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II. Enzyme Commission Number: EC 3.1.16.1. CAS No. 9068-54-6. PDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3543; spleen exonuclease; EC 3.1.16.1; 9068-54-6; 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II. Cat No: EXWM-3543. | |
| Spleen Extract, Bovine | Activities include Ro (SS-A), La (SS-B), Sm, and RNP. Group: Biologicals. Grades: Lysate. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Spleen, Rabbit | Spleen, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences. | Worldwide |
| Splenopentin diacetate | Splenopentin diacetate is a synthetic immunomodulating peptide corresponding to the region 32-34 of a splenic product called splenin (SP) and the thymic hormone thymopoietin (TP) respectively. It can reproduce the biological activities of TP and SP respectively. Uses: Splenopentin diacetate can reproduce the biological activities of tp and sp respectively. Synonyms: Splenopentin Acetate; SP-5; Splenin pentapeptide (32-36); Thymopoietin III pentapeptide (32-36). Grades: >98%. CAS No. 105184-37-0. Molecular formula: C35H59N9O13. Mole weight: 813.90. | |
| Spliceostatin A | Spliceostatin A is a potent splicing inhibitor. Spliceostatin A (SSA) causes cell cycle arrest at G1 and G2/M phases. Spliceostatin A treatment inhibits mitotic clonal expansion and adipogenesis. Spliceostatin A interaction with SF3B limits U1 snRNP availability and causes premature cleavage and polyadenylation. Spliceostatin A binds to the SF3B subcomplex of the U2 small nuclear ribonucleoprotein particle (snRNP), limits U1 snRNP availability in splicing, resulting in premature cleavage and polyadenylation of MALAT1, a nuclear lncRNA, as well as protein-coding mRNAs. Therefore, truncated transcripts are exported into the cytoplasm and translated, resulting in aberrant protein products. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 391611-36-2. Molecular formula: C28H43NO8. Mole weight: 521.65. Purity: >98%. IUPACName: (2Z,4S)-4-(Acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]-2,5-dimethyl-2H-pyran-3-yl]-2-pentenamide. Canonical SMILES: C[C@H](OC(C)=O)/C=C\C(N[C@H]1[C@@H](C)O[C@@H](C/C=C(C)/C=C/[C@@H](O[C@](C)(OC)C2)[C@@H](O)[C@@]32CO3)[C@@H](C)C1)=O. Product ID: ACM391611362. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spliceostatin A | Spliceostatin A, the FR901464 (HY-16212) methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia (CLL) cells[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 391611-36-2. Pack Sizes: 1 mg. Product ID: HY-16466. | |
| Splitomicin | Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD + -dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC 50 of 60 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Splitomycin. CAS No. 5690-3-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100585. | |
| Splitomicin | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Splitomicin | Splitomicin is a cell-permeable lactone derived from naphthol and known to be a potent selective inhibitor of Sir2 (silent information regulator 2) and HDAC. Splitomicin inhibits the NAD+-dependent deacetylase activity of Sir2 in vitro. It increases the levels of cyclic AMP by inhibiting the activity of cyclic AMP phosphodiesterase, interferes with mobilization of intracellular Ca+2 and ATP release. Synonyms: Splitomycin; 2-Hydroxy-1-Naphthalenepropionic Acid δ-Lactone; 2-Hydroxy-1-Naphthalenepropanoic Acid δ-Lactone; 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one; 1H-benzo[f]chromen-3(2H)-one; 1H,2H,3H-Naphtho[2,1-b]pyran-3-one; 1,2-Dihydro-3H-benzo[f]chromen-3-one. Grades: ≥98%. CAS No. 5690-3-9. Molecular formula: C13H10O2. Mole weight: 198.22. | |
| Splitomicin | Splitomicin. Group: Biochemicals. Grades: Purified. CAS No. 5690-3-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Splitomicin - CAS 5690-03-9 | A cell-permeable lactone derived from ?-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC?? = 60 μM). Group: Fluorescence/luminescence spectroscopy. | |
| Splitomicin (Splitomycin) | Potent inhibitor of yeast NAD+-dependent histone deacetylase Sir2p (IC50 = 60uM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering ot blocking access to the acetylated histone binding pocket. Group: Biochemicals. Grades: Highly Purified. CAS No. 5690-3-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Splitomicin (Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid) | Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also in mammalian cells. Group: Biochemicals. Alternative Names: Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid. Grades: Highly Purified. CAS No. 5690-3-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C13H10O2. US Biological Life Sciences. | Worldwide |
| S-PMH | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| S-(P-NITROBENZYL)GLUTATHIONE | Synonyms: S-(P-NITROBENZYL)GLUTATHIONE; s-(4-nitrobenzyl)glutathione. CAS No. 6803-19-6. Molecular formula: C17H22N4O8S. Mole weight: 442.44. | |
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