American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

Search for products or services, then visit the suppliers website for prices or more information.

Product
SSR 149415 SSR 149415 is a potent and orally available vasopressin V1B antagonist (Ki = 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively), displaying >70-fold selectively for rat V1B over V1A, V2 oxytoxin and a range of other receptors and ion channels. SSR 149415 has been shown to inhibit stress-induced ACTH release and exhibit anxiolytic-like effects in anxiety models, therefore it is identified as a drug candidate for the treatment of anxiety and depression. Uses: Potential treatment of anxiety and depression. Synonyms: Nelivaptan; SSR149415; SR-149415; SR 149415;; (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 439687-69-1. Molecular formula: C30H32ClN3O8S. Mole weight: 630.11. BOC Sciences 10
SSR 180711 hydrochloride SSR 180711 hydrochloride is a partial agonist at α7 nAChR. It enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. SSR 180711 leads to an increase of extracellular dopamine levels in rat prefrontal cortex and also exhibits antidepressant-like properties. Synonyms: SSR 180711 hydrochloride; SSR180711 hydrochloride; SSR-180711 hydrochloride; 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 446031-79-4. Molecular formula: C14H17BrN2O2.HCl. Mole weight: 361.66. BOC Sciences 10
SSR180711 hydrochloride SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR ( K i =22 nM; IC 50 =30 nM) and human α7 n-AChR ( K i =14 nM; IC 50 =18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 446031-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19411. MedChemExpress MCE
SSR 240612 hydrochloride SSR 240612 is a bradykinin B1 receptor inhibitor, displaying selectivity for B1 receptor over B2 receptor with Ki values of 0.48-0.73 and 358-481 nM, respectively. Synonyms: SSR 240612; SSR-240612; SSR240612; SSR 240612 HCl. Grades: ≥95%. CAS No. 464930-42-5. Molecular formula: C42H52N4O7S·HCl. Mole weight: 793.41. BOC Sciences 10
SSR504734 SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38?nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 615571-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10715. MedChemExpress MCE
SSR 504734 SSR 504734 is a potent and orally bioactive GlyT-1 inhibitor blocking the ex vivo uptake of glycine reversibly in animal models of schizophrenia, anxiety and depression. Synonyms: D06SBS; SSR 504734; SSR504734; SSR-504734; 2-chloro-N-[(S)-phenyl-[(2S)-piperidin-2-yl]methyl]-3-(trifluoromethyl)benzamide hydrochloride. Grades: 99%. CAS No. 615571-23-8. Molecular formula: C20H20ClF3N2O.HCl. Mole weight: 433.29. BOC Sciences 11
SSR 69071 SSR 69071 is a potent and high affinity human leukocyte elastase (HLE) inhibitor (IC50 = 3.9 nM) that displays species-selectivity (Ki = 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase, respectively). SSR 69071 has been shown to inhibit HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduce infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Synonyms: SSR 69071; SSR69071; SSR-69071; 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: ≥98% by HPLC. CAS No. 344930-95-6. Molecular formula: C27H32N4O7S. Mole weight: 556.63. BOC Sciences 9
SSR 69071 SSR 69071. Group: Biochemicals. Grades: Purified. CAS No. 344930-95-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
s,s,s-Csdphen s,s,s-Csdphen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S,S,S-CsDphen, 676270-65-8. Product Category: Heterocyclic Organic Compound. CAS No. 676270-65-8. Molecular formula: C23H28N2O3S. Mole weight: 412.545020 [g/mol]. Purity: 0.96. IUPACName: N-[(1S,2S)-2-amino-1,2-diphenylethyl]-7,7-dimethyl-3-oxobicyclo[2.2.1]heptane-4-sulfonamide. Canonical SMILES: CC1(C2CCC1(C(=O)C2)S(=O)(=O)NC(C3=CC=CC=C3)C(C4=CC=CC=C4)N)C. Density: 1.28g/cm³. Product ID: ACM676270658. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
SST0116CL1 SST0116CL1 is a second-generation small molecule inhibitor of Hsp90, which leads to decreased expression of Hsp90 client proteins and reduced tumor cell proliferation and tumor growth. Grades: >98%. CAS No. 1202920-93-1. Molecular formula: C22H30N4O6. Mole weight: 446.50. BOC Sciences 10
SSTF SSTF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10-Phenyl-2'-(triphenylsilyl)-10H-spiro[acridine-9,9'-fluorene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1454372-37-2. Molecular formula: C49H35NSi. Mole weight: 665.89 g/mol. Product ID: ACM1454372372. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
SSTR5 antagonist 2 hydrochloride SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2988224-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114191B. MedChemExpress MCE
S-succinylglutathione hydrolase This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is S-succinylglutathione hydrolase. Group: Enzymes. Enzyme Commission Number: EC 3.1.2.13. CAS No. 50812-22-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3548; S-succinylglutathione hydrolase; EC 3.1.2.13; 50812-22-1. Cat No: EXWM-3548. Creative Enzymes
S-Sulfo-L-cysteine sodium salt S-Sulfo-L-cysteine sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 7381-67-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
S-Sulfo-L-cysteine Sodium Salt S-Sulfo-L-cysteine sodium salt is an EAA receptor agonist. It is also reported to be an agonist at mGlu1α and mGlu5a subtypes expressed in clonal RGT cell lines. Synonyms: L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (6CI,8CI); L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (9CI); NSC 344479; S-Sulfocysteine Monosodium Salt; S-Sulfocysteine Sodium Salt; Sodium Cysteine-S-sulfonate. Grades: 85%. CAS No. 7381-67-1. Molecular formula: C3H6NNaO5S2. Mole weight: 223.20. BOC Sciences 3
S-(-)-Sulpiride Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-benzamide; (-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide; (-)-Sulpiride; L-Sulpiride; Levobren; Levopraid; Levosulpiride; S-(-)-Sulpiride; S-Sulpiride; l-Sulpiride; Levopride; Sulpid. Grades: Highly Purified. CAS No. 23672-07-3. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
Worldwide
ST034307 ST034307 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor (IC50 = 2.3 μM) without significant activity on other AC isoforms. Synonyms: ST034307; ST 034307; ST-034307; 6-chloro-2-(trichloromethyl)chromen-4-one. CAS No. 133406-29-8. Molecular formula: C10H4Cl4O2. Mole weight: 297.95. BOC Sciences 11
ST 1059. 1-(2’,5’-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine (1-(2’,5’-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine) A metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects. Group: Biochemicals. Alternative Names: 1-(2’,5’-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine. Grades: Highly Purified. CAS No. 3600-87-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
ST 1059-d6. (Desglymidodrine-d6) ST 1059-d6(Desglymidodrine-d6). Group: Biochemicals. Alternative Names: 1-(2’,5’-Dimethoxyphenyl)-2-aminoethanol-d6; α-(Aminomethyl)-2,5-dimethoxy-benzyl Alcohol-d6; α-(Aminomethyl)-2,5-dimethoxy-benzenemethanol-d6; de-Glymidodrine, Desglymidodrine-d6. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C10H9D6NO3, Molecular Weight: 203.27. US Biological Life Sciences. USBiological 3
Worldwide
ST 1059(desglymidodrine) ST 1059(desglymidodrine). Group: Biochemicals. Alternative Names: 1-(2',5'-Dimethoxyphenyl)-2-aminoethanol; a-(Aminomethyl)-2,5-dimethoxy-benzyl alcohol; a-(Aminomethyl)-2,5-dimethoxy-benzenemethanol. Grades: Highly Purified. CAS No. 3600-87-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H15NO3. US Biological Life Sciences. USBiological 8
Worldwide
ST1326 ST1326. Group: Others. Synonyms: Teglicar. Purity: >99%. Mole weight: 399.611. Stability: 1 Year. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; Teglicar; ST1326; (R)-3-(3-tetradecylureido)-4-(trimethylammonio)butanoate. Cat No: FLBZ-089. Creative Enzymes
ST 148 ST 148 is a dopamine D2 receptor antagonist. Synonyms: ST148; ST-148; Cortexolone maleate; ST-148; EU-0101046; EU0101046; EU 0101046; (Z)-but-2-enedioic acid;5-(dimethylamino)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-1-sulfonamide. Grades: 99%. CAS No. 390803-40-4. Molecular formula: C27H36N4O3S.C4H4O4. Mole weight: 612.74. BOC Sciences 10
ST-193 ST-193 is a potent, broad-spectrum small-molecule inhibitor of arenavirus entry and exhibits submicromolar antiviral activity in vitro. ST-193 inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively. Synonyms: 1-(4-methoxyphenyl)-N-[(4-propan-2-ylphenyl)methyl]benzimidazol-5-amine; ST-193; ST 193; ST193. Grades: 99.86%. CAS No. 489416-12-8. Molecular formula: C24H25N3O. Mole weight: 371.47. BOC Sciences 9
ST1936 ST1936 is a selective, nanomolar affinity 5-HT 6 receptor agonist with K i values of 13 nM, 168 nM and 245 nM for human 5-HT 6 , 5-HT 7 and 5-HT 2B receptors, respectively. ST1936 also shows moderate affinity (K i of 300 nM) for human and rat α2 adrenergic receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1210-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103110. MedChemExpress MCE
ST 1936 oxalate ST 1936 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 1210-81-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
ST 1936 oxalate ST 1936 oxalate is a selective and high affinity agonist of 5-HT6 receptors (Ki = 13, 168, and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively). It also displays moderate affinity for human α2 adrenergic receptors (Ki = 300 nM). ST 1936 oxalate was shown to increase Ca2+ concentration and phosphorylation of Fyn kinase in cloned cells. Synonyms: ST 1936 oxalate; ST1936 oxalate; ST-1936 oxalate; 5-Chloro-3-[2-(dimethylamino)ethyl]-2-methylindole oxalate. Grades: ≥98% by HPLC. CAS No. 1210-81-7. Molecular formula: C13H17ClN2.C2H2O4. Mole weight: 326.78. BOC Sciences 10
ST-193 hydrochloride ST-193 hydrochloride is the hydrochloride salt of ST-193 which is a potent, broad-spectrum small-molecule inhibitor of arenavirus entry and exhibits submicromolar antiviral activity in vitro. Synonyms: 1-(4-methoxyphenyl)-N-[(4-propan-2-ylphenyl)methyl]benzimidazol-5-amine;hydrochloride; ST-193 hydrochloride; ST 193 hydrochloride; ST193 hydrochloride. Molecular formula: C24H26ClN3O. Mole weight: 407.94. BOC Sciences 9
ST 198 ST 198 is a dopamine D3 receptor antagonist. Synonyms: ST 198; ST198; ST-198; KS-00002WSM; DTXSID10694257; N-(4-[1,2,3,4-tetrahydroisoquinolin-2-yl]-butyl)-3-phenylacryl-amide; N-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-3-phenylprop-2-enamide. Grades: 99%. CAS No. 854924-64-4. Molecular formula: C22H26N2O. Mole weight: 334.45. BOC Sciences 10
ST247 ST247 is a selective and inverse peroxisome proliferator-activated receptor (PPAR)β/δ agonist with IC 50 value of 19 nm, 10-fold more potent than GSK0660 with IC50 value of 210 nM. Synonyms: ST247; ST-247; ST 247. methyl 3-(N-(4-(hexylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate. Grades: 98%. CAS No. 1356497-91-0. Molecular formula: C19H26N2O5S2. Mole weight: 426.55. BOC Sciences 10
ST271 ST271 is a potent inhibitor of protein tyrosine kinase ( PTK ), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC 50 s of 6.7 and 9 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 106392-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103097. MedChemExpress MCE
ST271 A potent inhibitor of protein tyrosine kinase (PTK). Synonyms: (E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide; 2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-; ST 271; ST-271; ST271. CAS No. 106392-48-7. Molecular formula: C16H20N2O2. Mole weight: 272.34. BOC Sciences 9
ST 2825 ST 2825 is a MyD88 pharmacologic inhibitor. It inhibited MyD88 dimerization in coimmunoprecipitation experiments. It interfered with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1beta-mediated activation of NF-kappaB transcriptional activity. Synonyms: ST-2825; ST 2825; ST2825. Grades: >98%. CAS No. 894787-30-5. Molecular formula: C27H28Cl2N4O5S. Mole weight: 591.51. BOC Sciences 9
ST-401 ST-401, a microtubule-targeting agent (MTA), is a brain-penetrant microtubule (MT) assembly inhibitor. ST-401 disrupts microtubule (MT) function through gentle and reverisible reduction in MT assembly that triggers mitotic delay and cell death in interphase. ST-401 shows a potent antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419942-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163737. MedChemExpress MCE
ST4206 ST4206 is a potent adenosine A2A antagonist. ST4206 showed neuroprotective effects against rotenone induced alterations instriatal slice preparations,supporting the idea that adenosineA2A receptor antagonists might also be promising neuroprotective agents against the toxicity. induced bymitochondrialcomplexinhibition. Synonyms: ST4206; ST-4206; ST 4206; 2-Butanone, 4-[6-amino-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-2-yl]-. CAS No. 1246018-36-9. Molecular formula: C12H14N8O. Mole weight: 286.29. BOC Sciences
ST638 ST638 is a tyrosine kinase inhibitor and PLD inhibitor. It suppresses tyrosine phosphorylation induced by tumor necrosis factor-α and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts. Uses: Enzyme inhibitors. Synonyms: (Z)-2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide. Grades: ≥98%. CAS No. 107761-24-0. Molecular formula: C19H18N2O3S. Mole weight: 354.4. BOC Sciences 9
ST7612AA1 ST7612AA1 is a potent Histone deacetylase (HDCA) inhibitor. It showed an in vitro activity in the nanomolar range associated with a remarkable in vivo antitumor activity. Uses: Cancer. Synonyms: ST7612AA1; ST 7612AA1; ST7612AA1; S-((S)-7-oxo-6-((R)-5-oxopyrrolidine-2-carboxamido)-7-(phenylamino)heptyl) ethanethioate. Grades: 98%. CAS No. 1428535-92-5. Molecular formula: C20H27N3O4S. Mole weight: 405.51. BOC Sciences 10
ST-836 ST-836, a dopamine receptor ligand, might have similar effect with dopamine and probably useful as an antiparkinsonian agent. Uses: St-836 is a dopamine receptor ligand and might have similar effect with dopamine and probably useful as an antiparkinsonian agent. Synonyms: ST-836; ST 836; ST836; N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazol-6-amine;ST-836;1148156-63-1;C23H34N4OS;SCHEMBL1193415;4067AH. Grades: 95%. CAS No. 1148156-63-1. Molecular formula: C23H34N4OS. Mole weight: 414.61. BOC Sciences 10
ST-836 hydrochloride ST-836 hydrochloride, the hydrochloride salt form of verubulin, a dopamine receptor ligand that antiparkinsonian effect. Synonyms: ST836 hydrochloride; ST 836 hydrochloride; N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazol-6-amine;hydrochlorideST-836 (hydrochloride)1415564-68-9C23H34N4OS. ClHDTXSID107353513876AHHY-15238ACS-0920; CS 0920; CS0920W-5910; W 5910; W5910N-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)eth. CAS No. 1415564-68-9. Molecular formula: C23H35ClN4OS. Mole weight: 451.07. BOC Sciences 10
ST91 ST91 is a α 2 -adrenoceptor (α 2 AR) agonist. ST91 activates both α 2A AR and non-α 2A AR subtypes to produce spinal antinociception [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4749-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103203. MedChemExpress MCE
ST 91 ST 91. Group: Biochemicals. Grades: Purified. CAS No. 4749-61-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
ST 91 ST 91 is an α2-adrenoceptor agonist that displays ~ 120-fold selectivity for α2 receptors over α1 receptors. It acts predominantly at non-α2A-adrenoceptors which may be of the α2C subtype. ST 91 exhibits antinociceptive activity and increases tail-flick latencies in Sasco and Harlan rats. Uses: Adrenergic alpha-agonists. Synonyms: ST 91; ST91; ST-91; N-(2,6-Diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 4749-61-5. Molecular formula: C13H19N3.HCl. Mole weight: 253.77. BOC Sciences 10
STA-1474 STA-1474 is a water-soluble prodrug of ganetespib (formerly STA-9090). STA-1474 will metabolize to Ganetespib, which is a potent Hsp90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibits tumor growth in the setting of murine xenografts. Synonyms: STA-1474; STA 1474; STA1474. Grades: >98%. CAS No. 1118915-78-8. Molecular formula: C20H21N4O6P. Mole weight: 444.38. BOC Sciences 10
STA-21 Cas No. 111540-00-2. BOC Sciences 11
STA-4783 STA-4783 Inhibitor. Uses: Scientific use. Product Category: T6170. CAS No. 488832-69-5. TARGETMOL CHEMICALS
STA-9584 STA-9584 is a potent vascular disrupting agent, which exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors. In vitro, 2-methoxy-5-(5-(3,4,5-trimethoxyphenyl)isoxazol-4-yl)aniline (STA-9122) (active metabolite of STA-9584) displayed increased potency relative to other tubulin-binding agents and was highly cytotoxic to tumor cells. STA-9584 induced significant tumor regressions in prostate and breast xenograft models in vivo and, in an aggressive syngeneic model, demonstrated superior tumor growth inhibition and a positive therapeutic index relative to combretastatin A-4 phosphate (CA4P). It is noteworthy that histological analysis revealed that STA-9584 disrupted microvasculature at both the center and periphery of tumors. Compared with CA4P, STA-9584 induced a 73% increase in central necrotic area, 77% decrease in microvasculature, and 7-fold increase in tumor cell apoptosis in the remaining viable rim 24 h post-treatment. Ultrasound imaging confirmed that STA-9584 rapidly and efficiently blocked blood flow in highly perfused tumor regions. Moreover, cardiovascular effects were evaluated in the Langendorff assay and telemetered dogs, and cardiovascular toxicity was not predicted to be dose-limiting. This bioactivity profile distinguishes STA-9584 from the combretastatin class and identifies the compound as a promising new therapeutic VDA candidate. Synonyms: STA 9584; STA9584. CAS No. 906481-23-0. Molecular formula: C28H30ClN3O6. Mole weight: 540.01. BOC Sciences 11
Stabilized Gold Nanoparticles Stabilized Gold Nanoparticles. Uses: Conjugate development, immunostaining, lateral flow assays, biological sensor development (e.g. lspr-based assays), electron microscopy, dark field microscopy, surface enhanced raman spectroscopy (sers). Group: other s. Alfa Chemistry Materials 3
Stabilizer 9000 (technical grade) Stabilizer 9000 (technical grade). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4-Diisocyanato-1,3,5-tris(1-methyl)-benzene homopolymer. Product Category: Promotional Products. CAS No. 29963-44-8. Purity: Tech. Product ID: ACM29963448-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Stachartin B Stachartin B is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone B; Spiro[benzo[2,1-b:3,4-c']difuran-2(8H),1'(2'H)-naphthalen]-8-one, 3,3',4',4'a,5',6,6',7',8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 1978388-55-4. Molecular formula: C23H30O5. Mole weight: 386.48. BOC Sciences 5
Stachartin D Stachartin D is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone D. Grades: 97.0%. CAS No. 1978388-57-6. Molecular formula: C30H43NO6. Mole weight: 513.67. BOC Sciences 5
Stachybocin A It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.3 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.3 X 10-5 and 7.9 X 10-6, respectively. Synonyms: Spirodihydrobenzofuranlactam ?; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'S*)], 2'a, 4'aa, 6'a, 8'ab]]-; AM 6222A. CAS No. 158827-60-2. Molecular formula: C52H70N2O10. Mole weight: 883.12. BOC Sciences 5
Stachybocin B It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.8 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.2 X 10-5 and 9.5 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'S,7'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'S*)], 2'a, 4'aa, 6'a, 7'a, 8'ab]]-; AM 6222B. CAS No. 158827-61-3. Molecular formula: C52H70N2O11. Mole weight: 899.12. BOC Sciences 5
Stachybocin C It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.9 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.5 X 10-5 and 9.4 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'S,7'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'aS*)], 2'a, 4'aa, 6'a, 7'a, 8'ab]]-; AM 6222C. CAS No. 158827-62-4. Molecular formula: C52H70N2O11. Mole weight: 899.12. BOC Sciences 5
Stachybotramide Stachybotramide is produced by the mycelia and culture broth of Stachybotrys sp. Stachybotramide can stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). Synonyms: Spirodihydrobenzofuranlactam II; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; Stachybotrin; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-. Grades: 97.5%. CAS No. 149598-71-0. Molecular formula: C25H35NO5. Mole weight: 429.55. BOC Sciences 5
Stachybotrin A It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. CAS No. 144373-26-2. Molecular formula: C23H31NO5. Mole weight: 401.49. BOC Sciences 5
Stachybotrin B It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. Synonyms: (+)-Stachybotrin B. CAS No. 144385-02-4. Molecular formula: C23H31NO4. Mole weight: 385.50. BOC Sciences 5
Stachybotrin C It is a neuritogenic agent produced by the strain of Stachyborrys parvispora F4708. It promotes the enlargement of the neural sinus of P12 cells, and the effect of Stachybotrin C is obvious, but the effect of Parvisporin is weak. Synonyms: Pyrano[2,3-e]isoindol-7(2H)-one, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, (2R,3R)-rel-; Pyrano[2,3-e]isoindol-7(2H)-one, 2-(4,8-dimethyl-3,7-nonadienyl)-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, [2a(E),3a]-; Antibiotic NG 245. CAS No. 150351-23-8. Molecular formula: C31H39NO5. Mole weight: 505.64. BOC Sciences 5
Stachybotrolide Stachybotrolide is produced by Stachybotrys alternans. Synonyms: Stachybotrylactone; (2R,2'R,4a'S,6'R,8a'S)-4,6'-dihydroxy-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzo[2,1-b:3,4-c']difuran-2,1'-naphthalen]-6(8H)-one; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 149691-31-6. Molecular formula: C23H30O5. Mole weight: 386.48. BOC Sciences 5
Stachybotrylactam An unusual spirodihydrobenzofuranlactam mycotoxin isolated from Stachybotrys sp. It shows immunosuppressant and weak HIV protease activity and shows diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition. Synonyms: 2-deoxy F1839A; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-3', 4', 4'a, 5', 6', 7, 7', 8, 8', 8'a-Decahydro-4, 6'-dihydroxy-2', 5', 5', 8'a-tetramethyl-spiro[2H-furo[2, 3-e]isoindole-2, 1'(2'H)-naphthalen]-6(3H)-one; Spirodihydrobenzofuranlactam I. Grades: >95% by HPLC. CAS No. 163391-76-2. Molecular formula: C23H31NO4. Mole weight: 385.50. BOC Sciences 5
Stachybotrylactam (2-deoxy Antibiotic F1839A) Isolated from a Stachybotrys sp., this unusual spirodi hydrobenzofuranlactam mycotoxin shows immuno-suppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition. Group: Biochemicals. Alternative Names: 2-deoxy Antibiotic F1839A. Grades: Highly Purified. CAS No. 163391-76-2. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 1
Worldwide
Stachybotrysin B Stachybotrysin B is a fungal metabolite produced by the strain of S. chartarum. It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM). Stachybotrysin B is also cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively). Synonyms: (2R,2'R,4a'S,6'R,8a'S)-7-formyl-4-hydroxy-6-(hydroxymethyl)-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzofuran-2,1'-naphthalen]-6'-yl acetate. Grades: >95% by HPLC. CAS No. 2098376-42-0. Molecular formula: C25H34O6. Mole weight: 430.53. BOC Sciences 7
Stachydrine Stachydrine. Group: Biochemicals. Grades: Plant Grade. CAS No. 471-87-4. Pack Sizes: 20mg. Molecular Formula: C7H13NO2, Molecular Weight: 143.18. US Biological Life Sciences. USBiological 9
Worldwide
Stachydrine Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway. Uses: Scientific research. Group: Natural products. CAS No. 471-87-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0298. MedChemExpress MCE
Stachydrine hydrochloride Stachydrine hydrochloride is the major active constituent of Leonurus artemisia , which is a potential therapy for cardiovascular diseases [2]. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 4136-37-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0738. MedChemExpress MCE
Stachydrine Hydrochloride Stachydrine hydrochloride is extracted from the flower of Chrysanthemum parthenium. It promoted the protein expression of IL-12 and IL-6, as well as the mRNA expression of T-bet and RORγt, while inhibiting the mRNA expression of GATA-3 and Foxp3. Group: Biochemicals. Alternative Names: Turicine HCl; (S)-2-Carboxy-1,1-dimethylpyrrolidinium chloride; 2-Carboxy-1,1-dimethylpyrrolidinium chloride. Grades: Highly Purified. CAS No. 4136-37-2. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 8
Worldwide
Stachyose a-D-Gal-a-D-Gal-a-D-Glc-b-D-Frc. CAS No. 10094-58-3. Product ID: 3-00211. Molecular formula: C24H42O21. 4 H2O. Mole weight: 738.64. Properties: powder. MFCD No. MFCD00006630. CarboMer Inc
Stachyose Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 470-55-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7910. MedChemExpress MCE
Stachyose - 70% Stachyose - 70% is a remarkable and meticulously extracted natural compound, derived from plants. Renowned for its elevated content of stachyose, this sublime constituent aids in studying afflictions such as diabetes, gastrointestinal anomalies and metabolic syndromes. Synonyms: b-D-Fructofuranosyl-O-a-D-galactopyranosyl-1-6-O-a-D-galactopyranosyl-1-6-a-D-glucopyranoside. CAS No. 470-55-3. Molecular formula: C24H42O21. Mole weight: 666.59. BOC Sciences 12
Stachyose hydrate Stachyose hydrate is a natural oligosaccharide commonly found in plant sources acting as a prebiotic aiding in the research of beneficial gut bacteria. Synonyms: Lupeose. CAS No. 54261-98-2. Molecular formula: C24H42O21·xH2O. Mole weight: 666.58 (anhydrous basis). BOC Sciences 9
Stachyose hydrate Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis ( Apoptosis ). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 54261-98-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0299. MedChemExpress MCE
Stachyose tetrahydrate Stachyose tetrahydrate is a prebiotic with few side effects. It can be used in health products. Synonyms: Stachyose tetrahydrate; 10094-58-3; Stachyose (tetrahydrate); stachyose hydrate; (2S,3R,4S,5R,6R)-2-[[(2R,3R,4S,5R,6S)-6-[[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol; tetrahydrate; Stachyose hydrate(1:x); D-Stachyose tetrahydrate; 54261-98-2; STACHYOSETETRAHYDRATE; CHEBI:183019; s5102; AKOS025311600; CCG-270424; MS-31281; HY-113529; CS-0062651; C13982; W-106081; W-200640. Grades: 98%. CAS No. 10094-58-3. Molecular formula: C24H42O21. Mole weight: 666.57. BOC Sciences 12

Would you like to list your products on USA Chemical Suppliers?

Our database is helping our users find suppliers everyday.

Add Your Products