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| Product | Description | |
|---|---|---|
| SPR741 | SPR741 is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA. Synonyms: NAB741. Grades: >98%. CAS No. 1179330-52-9. Molecular formula: C44H73N13O13. Mole weight: 992.13. |  |
| S-Pralatrexate | The S isometric form of Pralatrexate which is a 10-deazaaminopterin analog of methotrexate, and is an inhibitor of DHFR. Synonyms: Pralatrexate, (S)-; 1320211-69-5; UNII-0892G4T376; 0892G4T376; L-Glutamic acid, N-(4-((1S)-1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-; (4-((S)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid; (S)-pralatrexate; SCHEMBL1890561; DTXSID601031325; AKOS040747300; Q27236394; (2S)-2-[[4-[(2S)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid. Grades: > 95%. CAS No. 1320211-69-5. Molecular formula: C23H23N7O5. Mole weight: 477.48. | |
| Spray Nozzles | Spray Nozzles. Group: Polymers. |  |
| SPRi 3 | SPRi 3 is a potent inhibitor of sepiapterin reductase (SPR) with IC50 value of 53-74 nM for human SPR. It inhibits BH4 synthesis pathway and attenuates proliferation in naive CD4+ T cells. Synonyms: N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide. Grades: ≥98% by HPLC. CAS No. 1292285-54-1. Molecular formula: C14H18N2O3. Mole weight: 262.3. | |
| S-(-)-Propanolol HCl | (S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride. active enantiomer, 5-HT1 receptor antagonist. CAS No. 4199-10-4. Product ID: 1-01020. Molecular formula: C16H21NO2. Mole weight: 295.81. Properties: (S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride. |  |
| S-Propargylcysteine | S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H 2 S-releasing compound. S-Propargylcysteine reduces Ca 2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPRC. CAS No. 3262-64-4. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W001538. |  |
| S-Propargyl-Cysteine | S-Propargyl-cysteine (SPRC) is a modulator of endogenous hydrogen disulfide (H2S) with antioxidant activity. SPRC is potentially used for the treatment of Alzheimer's disease (TNF signaling, the NF-κB pathway and the ERK1/2 pathway), anemia of inflammation (IL-6/JAK2/STAT3 pathway), ischemic heart disease (H2S/VEGFR2/STAT3 pathway) and myocardial infarction. Synonyms: (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid; SPRC. Grades: 98%. CAS No. 3262-64-4. Molecular formula: C6H9NO2S. Mole weight: 159.21. | |
| S-Propyl-2-thiobarbituric Acid | S-Propyl-2-thiobarbituric Acid. Group: Biochemicals. Alternative Names: 6-Hydroxy-2-(propylthio)-4(1H)-pyrimidinone; 2-(Propylthio)pyrimidine-4,6-diol. Grades: Highly Purified. CAS No. 145783-12-6. Pack Sizes: 250mg. Molecular Formula: C7H10N2O2S, Molecular Weight: 186.23. US Biological Life Sciences. |  Worldwide |
| S-Propyl-5-nitro-2-thiobarbituric Acid | S-Propyl-5-nitro-2-thiobarbituric Acid. Group: Biochemicals. Alternative Names: 6-Hydroxy-5-nitro-2-(propylthio)-4(1H)-pyrimidinone; 5-Nitro-2-(propylthio)pyrimidine-4,6-diol. Grades: Highly Purified. CAS No. 145783-13-7. Pack Sizes: 100mg. Molecular Formula: C7H9N3O4S, Molecular Weight: 231.23. US Biological Life Sciences. | Worldwide |
| S-Propyl-5-nitro-2-thiobarbituric-d7 Acid | S-Propyl-5-nitro-2-thiobarbituric-d7 Acid. Group: Biochemicals. Alternative Names: 6-Hydroxy-5-nitro-2-(propylthio)-4(1H)-pyrimidinone-d7; 5-Nitro-2-(propylthio)pyrimidine-4,6-diol-d7. Grades: Highly Purified. CAS No. 1265919-34-3. Pack Sizes: 10mg. Molecular Formula: C7H2D7N3O4S, Molecular Weight: 238.27. US Biological Life Sciences. | Worldwide |
| S(+)-Propylene glycol | 1g Pack Size. Group: Building Blocks, Organics, Solvents. Formula: C3H8O2. CAS No. 4254-15-3. Prepack ID 43121408-1g. Molecular Weight 76.09. See USA prepack pricing. |  |
| S-Propylglutathione | Cas No. 24425-53-4. Mole weight: 349.40. | |
| S-Propyl N,N-Diethyldithiocarbamate | S-Propyl N, N-Diethyl dithiocarbamate. Group: Biochemicals. Alternative Names: N,N-Diethyl S-propyl Dithiocarbamate. Grades: Highly Purified. CAS No. 19047-77-9. Pack Sizes: 250mg. Molecular Formula: C8H17NS2, Molecular Weight: 191.36. US Biological Life Sciences. | Worldwide |
| S-Propyl N,N-Diethyldithiocarbamate-d7 | S-Propyl N,N-Diethyldithiocarbamate-d7. Group: Biochemicals. Alternative Names: N,N-Diethyl S-propyl Dithiocarbamate-d7. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C8H10D7NS2, Molecular Weight: 198.4. US Biological Life Sciences. | Worldwide |
| Spruce Oil Type | Spruce Oil Type. CAS No. MIXTURE. Kosher: Y. VIGON Item # 504148. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| SpStrongylocin 1 | SpStrongylocin 1 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Ile-Phe-Asn-Ser-Ile-Tyr-His-Arg-Lys-Cys-Val-Val-Lys-Asn-Arg-Cys-Glu-Thr-Val-Ser-Gly-His-Lys-Thr-Cys-Lys-Asp-Leu-Thr-Cys-Cys-Arg-Ala-Val-Ile-Phe-Arg-His-Glu-Arg-Pro-Glu-Val-Cys-Arg-Pro-Ser-Thr. | |
| SpStrongylocin 2 | SpStrongylocin 2 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Trp-Asn-Pro-Phe-Arg-Lys-Leu-Tyr-Arg-Lys-Glu-Cys-Asn-Asp-Val-Thr-Ser-Cys-Asp-Thr-Val-Ser-Gly-Val-Lys-Thr-Cys-Thr-Lys-Lys-Asn-Cys-Cys-His-Arg-Lys-Phe-Phe-Gly-Lys-Thr-Ile-Leu-Lys-Ala-Pro-Glu-Cys-Thr-Val-Ile-Ser. | |
| SPT Imidazopyridine 1 | SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats. Synonyms: SPT-IN-1; SPT IN 1; SPT Inhibitor 1; Imidazopyridine 1; 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid; 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid; SPT-IN-1. Grades: ≥98%. CAS No. 1933533-18-6. Molecular formula: C22H24N2O3. Mole weight: 364.44. | |
| Sp-TTP-α-S | Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable. Uses: Antiviral agents. Synonyms: Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer. Grades: ≥ 95% by HPLC. CAS No. 83199-32-0. Molecular formula: C10H17N2O13P3S (free acid). Mole weight: 498.2 (free acid). | |
| S-PVC | S-PVC. Group: Polymers. | |
| SQ01 | SQ01. Uses: Designed for use in research and industrial production. Product Category: Dye-Sensitized Solar Cell (DSSC). CAS No. 951248-19-4. Product ID: ACM951248194. Alfa Chemistry ISO 9001:2015 Certified. Categories: SQ109. |  |
| SQ02 | SQ02. Uses: Designed for use in research and industrial production. Product Category: Dye-Sensitized Solar Cell (DSSC). CAS No. 1240041-84-2. Product ID: ACM1240041842. Alfa Chemistry ISO 9001:2015 Certified. Categories: SQL:2003. | |
| SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC 50 for cell killing of 50±8 nM. SQ109, targets MmpL3 , is an antitubercular agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 722041. CAS No. 502487-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14989. | |
| SQ109 | SQ109 is a novel antitubercular drug. It was screened out from a big chemical library designed around the active pharmacophore of ethambutol (EMB). SQ109 displayed potent activity against all the substrains of Mtb including XDR- and MDR-TB clinical strains. Synonyms: SQ109; SQ-109; SQ 109; NSC 722041; NSC-722041; NSC722041. Grades: >98%. CAS No. 502487-67-4. Molecular formula: C22H38N2. Mole weight: 330.55. | |
| SQ 22536 | SQ 22536. Group: Biochemicals. Grades: Purified. CAS No. 17318-31-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SQ-22536 | SQ-22536, also known as NSC 53339, is a cell-permeable adenylyl cyclase inhibitor (IC50 = 20 μM in detergent-dispersed rat brain preparation). SQ 22536 has demonstrated inhibition of the effect of glucagon on rat membrane cyclase activity and has reduced the effect of isoproterenol, epinephrine, norepinephrine, and phenylephrine. Synonyms: 9-(tetrahydro-2-furanyl)-9H-purin-6-amine; SQ-22536; SQ22536; SQ 22536; SQ-22,536; SQ22,536; SQ 22,536. NSC 53339. CAS No. 17318-31-9. Molecular formula: C9H11N5O. Mole weight: 205.22. | |
| SQ28603 | SQ28603 is a selective neutral endopeptidase (NEP 3.4.24.11) inhibitor. Synonyms: 3-[(2-benzyl-3-sulfanylpropanoyl)amino]propanoic acid; SQ 28,603; SQ 28603; SQ-28603. CAS No. 100845-83-8. Molecular formula: C13H17NO3S. Mole weight: 267.34. | |
| SQ 29548 | SQ 29548 is a potent and selective TP receptor antagonist. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM. Synonyms: SQ-29548; SQ29548; (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 98672-91-4. Molecular formula: C21H29N3O4. Mole weight: 387.5. | |
| SQDG | SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123036-44-2. Pack Sizes: 1 mg. Product ID: HY-143692. | |
| Squalamine | Squalamine is an aminosterol compound with potent broad spectrum antiviral activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3beta-N-1-(N-[3-(4-Aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate. Product Category: Inhibitors. Appearance: Solid. CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 628. Purity: 95%+. IUPACName: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate. Canonical SMILES: C[C@@]12[C@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CC[C@H](C(C)C)OS(=O)(O)=O)C)([H])C[C@@H](NCCCNCCCCN)CC1. Density: 1.13±0.1 g/cm³. Product ID: ACM148717902. Alfa Chemistry ISO 9001:2015 Certified. | |
| Squalamine | Squalamine is a naturally derived broad-spectrum antibiotic that is predominantly derived from the livers of dogfish and other shark species. Squalamine is undergoing trials for treatment of non-small cell lung cancer (stage I/IIA) as well as general phase I pharmacokinetic studies. In 2005, the Food and Drug Administration granted squalamine Fast Track status for approval for treatment of age-related macular degeneration. However, the Genaera Corporation, the company that has done the most work with squalamine, discontinued trials for its use in treating prostate cancer and wet age-related macular degeneration in 2007. The Squalamine project was acquired by Ohr Pharmaceutical from the now liquidated Genaera, with the prospect of continuing the development of this drug to treat wet age-related macular degeneration. Synonyms: MSI 1256; MSI-1256; MSI1256. Grades: ≥98% (HPLC). CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 627.96. | |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson , s disease mouse models [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | Squalane is commonly used as an emollient and moisturizer. Synonyms: 2,6,10,15,19,23-hexamethyltetracosane. CAS No. 111-01-3. Molecular formula: C30H62. Mole weight: 422.81. | |
| Squalane | 100g Pack Size. Group: Building Blocks, Organics. Formula: [(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2]2. CAS No. 111-01-3. Prepack ID 13053317-100g. Molecular Weight 422.81. See USA prepack pricing. | |
| Squalane | United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; hydrocarbons & petrochemicals; european pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosane, perhydrosqualene,Squalane. CAS No. 111-01-3. Pack Sizes: 500MG. IUPAC Name: 2,6,10,15,19,23-hexamethyltetracosane. Molecular Formula: C30H62. Mole Weight: 422.81. Catalog: APS111013. SMILES: CC (C)CCCC (C)CCCC (C)CCCCC (C)CCCC (C)CCCC (C)C. Format: Neat. |  |
| Squalane | Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 111-01-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7113. | |
| Squalane | 2,6,10,15,19,23-Hexamethyltetraccosane. Grades: >99.5%. CAS No. 111-01-3. Product ID: 8-05091. Molecular formula: C30H62. Mole weight: 422.82. Purity: d 0.812 vegetable derived Squalane. | |
| Squalane | Squalane. Group: Biochemicals. Alternative Names: 2,6,10,15,18,23-Hexamethyltetracosane. Grades: Highly Purified. CAS No. 111-01-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C30H62. US Biological Life Sciences. | Worldwide |
| Squalane-d62 | Isotope labelled Squalane is used as an emollient and moisturizer in cosmetic applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 16514-83-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C30D62, Molecular Weight: 485.2. US Biological Life Sciences. | Worldwide |
| Squalane NF | 2,6,10,15,19,23-Hexamethyltetraccosane. health foods. Grades: NF. CAS No. 111-01-3. Product ID: 1-01080. Molecular formula: C30H62. Mole weight: 422.82. Properties: >99.5%. | |
| SQUALANE OIL | Synonyms: SQUALANE OIL. CAS No. 59030-00-1. | |
| Squalane-ß-cyclodextrin complex | Squalane-b-Cyclodextrin. Product ID: 4-00545. Purity: 4:6 powder. | |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| Squalene | 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetraccosene. cosmetic and pharmaceutical excipient. CAS No. 111-02-4. Product ID: 1-01081. Molecular formula: C30H50. Mole weight: 410.73. Purity: 0.998. Properties: iodine value 0.01. | |
| Squalene | Squalene Inhibitor. Uses: Scientific use. Product Category: T4749. CAS No. 111-02-4. |  |
| Squalene | Squalene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Squalene | Squalene - Product ID: NST-10-137. Category: Triterpens. Alternative Names: (E,E,E,E)-Squalene, all-trans-Squalene, Spinacen, Squalen, trans-Squalene. Purity: 98%. Test method: GC. CAS No. 111-02-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Colourless to light yellow liquid. Molecular formula: C30H50. Mole weight: 410.7. Storage: +2 +8 °C. |  |
| Squalene 2,3:22,23-Dioxide | Squalene 2,3:22,23-Dioxide is formed from he epoxidation of 2,3-oxidosqualene, by squalene epoxidase. Squalene 2,3:22,23-Dioxide is accumulated intracellularly during the inhibition of cholesterol biosynthesis in Chinese hamster ovary cells. Group: Biochemicals. Alternative Names: 2,3:22,23-Dioxidosqualene; Squalene 2,3:22,23-Diepoxide; (all-E)-2,3:22,23-Diepoxy-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene; 2,2'-(3,7,12,16-Tetramethyl-3,7,11,15-octadecatetraene-1,18-diyl)bis[3,3-dimethyl-oxirane]. Grades: Highly Purified. CAS No. 31063-19-1. Pack Sizes: 25mg. Molecular Formula: C30H50O2, Molecular Weight: 442.72. US Biological Life Sciences. | Worldwide |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. |  |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| squalene methyltransferase | Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form. Group: Enzymes. Synonyms: TMT-1; TMT-2. Enzyme Commission Number: EC 2.1.1.262. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1867; squalene methyltransferase; EC 2.1.1.262; TMT-1; TMT-2. Cat No: EXWM-1867. | |
| squalene monooxygenase | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Enzyme Commission Number: EC 1.14.14.17. CAS No. 9029-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0914; squalene monooxygenase; EC 1.14.14.17; 9029-62-3; squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Cat No: EXWM-0914. | |
| Squalene (Standard) | Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 111-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214R. | |
| squalene synthase | This microsomal enzyme catalyses the first committed step in the biosynthesis of sterols. The enzyme from yeast requires either Mg2+ or Mn2+ for activity. In the absence of NAD(P)H, presqualene diphosphate (PSPP) is accumulated. When NAD(P)H is present, presqualene diphosphate does not dissociate from the enzyme during the synthesis of squalene from farnesyl diphosphate (FPP). High concentrations of FPP inhibit the production of squalene but not of PSPP. Group: Enzymes. Synonyms: farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Enzyme Commission Number: EC 2.5.1.21. CAS No. 9077-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2758; squalene synthase; EC 2.5.1.21; 9077-14-9; farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Cat No: EXWM-2758. | |
| Squalestatin A | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grades: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73. | |
| Squalestatin B | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70. | |
| Squalestatin C | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50. | |
| Squamatic acid | Synonyms: Squamatsaure; 2-Hydroxy-4-methoxy-6-methyl-1,3-benzenedicarboxylic acid 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 2-Oxy-6-methoxy-4-methyl-isophthalsaeure-3-(3-oxy-2,5-dimethyl-4-carboxy-phenylester). CAS No. 569-36-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Squaric Acid | Crystalline, purity 99+%. Synonyms: 3,4-Dihydroxy-3-cyclobutene-1,2-dione. CAS No. 2892-51-5. Pack Sizes: 10g, 50g. Product ID: FR-0532. M.P. >300. Mole weight: 114.06. |  Frinton Laboratories |
| Squarunkin A hydrochloride | Squarunkin A is an inhibitor of UNC119 chaperone protein-cargo interaction. It inhibits the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A with an IC50 value of 10?nm. It binds to UNC119 proteins in cell lysate and interferes with the activation of Src kinase. Synonyms: Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 2253744-55-5. Molecular formula: C25H32F3N5O4·HCl. Mole weight: 560.01. | |
| Squaw Vine Powder | Squaw Vine Powder. |  CA, FL & NJ |
| SR-01000946410 | SR-01000946410 is a structural analog of PGE2 and a selective agonist for the EP2 receptor subtype. It binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor. It does not bind appreciably to any of the other murine EP receptors. BIt has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4979. Grades: ≥98%. CAS No. 69685-22-9. Molecular formula: C24H40O5. Mole weight: 408.6. | |
| SR 0987 | SR 0987 is a T cell-specific RORγ (RORγt) agonist (EC50 = 800 nM in a gene reporter assay) that induces IL-17 expression and decreases PD-1 expression in T cells in vitro. Synonyms: SR-0987; SR0987; SR 0987; 2-Chloro-N-[4-[2, 2, 2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl]phenyl]benzamide. Grades: ≥98% by HPLC. CAS No. 303126-97-8. Molecular formula: C16H10ClF6NO2. Mole weight: 397.7. | |
| SR1001 | Retinoic-acid-receptor-related orphan receptors (ROR) α and γ play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist at these receptors. SR 1001 has been shown to suppress IL-17 promoter driven transcriptional activity by inhibiting the interaction of co-activators such as TRAP220 nuclear receptor box 2 peptide (IC50 = 117 nM) and SRC2 with RORα and RORγ as well as by increasing the recruitment of corepressors such as NCoR. At 5 μM, SR 1001 inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs. A 25 mg/kg dose of SR 1001 twice/day delays the onset and the severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Synonyms: SR 1001; SR-1001. Grades: >98%. CAS No. 1335106-03-0. Molecular formula: C15H13F6N3O4S2. Mole weight: 477.4. | |
| SR1001 | SR1001 is a selective ROR α and ROR γt inverse agonist with K i s 172 and 111 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR 10067 | SR 10067 is a selective and cell-permeable Rev-Erbα/β agonist (IC50 = 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively). SR 10067 has no significant activity against a wide range of nuclear receptors, other receptors, ion channels and transporters at 20 μM. SR 10067 has effects of increasing wakefulness, reducing REM and slow wave sleep in vivo. Synonyms: SR 10067; SR-10067; SR-10067; [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone. Grades: ≥98% by HPLC. CAS No. 1380548-02-6. Molecular formula: C31H31NO3. Mole weight: 465.58. | |
| SR1078 | SR 1078 is a selective agonist of RORα and RORγ that stimulates ROR transcriptional activity in HEK293 cell reporter assays. Synonyms: SR 1078; SR-1078. Grades: >98%. CAS No. 1246525-60-9. Molecular formula: C17H10F9NO2. Mole weight: 431.25. | |
| SR 11023 | SR 11023 is an orally active antagonist of PPAR γ, with the IC 50 value of 109 nM that plays an important role in diabetic research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820602-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160162. | |
| SR 11237 | SR 11237 is a pan retinoid X receptor (RXR) agonist with no RAR activity. Synonyms: SR12813; SR 12813; SR-12813. 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid. Grades: ≥98% by HPLC. CAS No. 146670-40-8. Molecular formula: C24H28O4. Mole weight: 380.48. | |
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