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| Product | Description | |
|---|---|---|
| Sp-TTP-α-S | Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable. Uses: Antiviral agents. Synonyms: Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer. Grades: ≥ 95% by HPLC. CAS No. 83199-32-0. Molecular formula: C10H17N2O13P3S (free acid). Mole weight: 498.2 (free acid). |  |
| S-PVC | S-PVC. Group: Polymers. |  |
| SQ02 | Dye-Sensitized Solar Cell (DSSC). CAS No. 1240041-84-2. Catalog: ACM1240041842. |  |
| SQ109 | SQ109 is a novel antitubercular drug. It was screened out from a big chemical library designed around the active pharmacophore of ethambutol (EMB). SQ109 displayed potent activity against all the substrains of Mtb including XDR- and MDR-TB clinical strains. Synonyms: SQ109; SQ-109; SQ 109; NSC 722041; NSC-722041; NSC722041. Grades: >98%. CAS No. 502487-67-4. Molecular formula: C22H38N2. Mole weight: 330.55. | |
| SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC 50 for cell killing of 50±8 nM. SQ109, targets MmpL3 , is an antitubercular agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 722041. CAS No. 502487-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14989. |  |
| SQ 22536 | SQ 22536. Group: Biochemicals. Grades: Purified. CAS No. 17318-31-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SQ-22536 | SQ-22536, also known as NSC 53339, is a cell-permeable adenylyl cyclase inhibitor (IC50 = 20 μM in detergent-dispersed rat brain preparation). SQ 22536 has demonstrated inhibition of the effect of glucagon on rat membrane cyclase activity and has reduced the effect of isoproterenol, epinephrine, norepinephrine, and phenylephrine. Synonyms: 9-(tetrahydro-2-furanyl)-9H-purin-6-amine; SQ-22536; SQ22536; SQ 22536; SQ-22,536; SQ22,536; SQ 22,536. NSC 53339. CAS No. 17318-31-9. Molecular formula: C9H11N5O. Mole weight: 205.22. | |
| SQ28603 | SQ28603 is a selective neutral endopeptidase (NEP 3.4.24.11) inhibitor. Synonyms: 3-[(2-benzyl-3-sulfanylpropanoyl)amino]propanoic acid; SQ 28,603; SQ 28603; SQ-28603. CAS No. 100845-83-8. Molecular formula: C13H17NO3S. Mole weight: 267.34. | |
| SQ 29548 | SQ 29548 is a potent and selective TP receptor antagonist. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM. Synonyms: SQ-29548; SQ29548; (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 98672-91-4. Molecular formula: C21H29N3O4. Mole weight: 387.5. | |
| SQDG | SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123036-44-2. Pack Sizes: 1 mg. Product ID: HY-143692. | |
| SQDG | Bioactive Lipids. Alternative Names: Sulfoquinovosyldiacylglycerol. CAS No. 123036-44-2. Molecular formula: C43H79NO12S. Mole weight: 834.15. Appearance: Powder. Purity: >99%. IUPACName: [(2S,3S,4S,5R,6S)-6-[(2S)-2-hexadecanoyloxy-3-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]oxypropoxy]-3,4,5-trihydroxyoxan-2-yl]methanesulfonic acid. Canonical SMILES: CCCCCCCCCCCCCCCC (=O)O[C@@H] (CO[C@@H]1[C@@H] ([C@H] ([C@@H] ([C@H] (O1)CS (=O) (=O)O)O)O)O)COC (=O)CCCCCCC/C=C\C/C=C\C/C=C\CC. Catalog: ACM123036442. | |
| Squalamine | Squalamine is an aminosterol compound with potent broad spectrum antiviral activity. Group: Inhibitors. Alternative Names: 3beta-N-1-(N-[3-(4-Aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate. CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 628. Appearance: Solid. Purity: 95%+. IUPACName: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate. Canonical SMILES: C[C@@]12[C@] (C[C@@H] (O)[C@]3 ([H])[C@]2 ([H])CC[C@@]4 (C)[C@@]3 ([H])CC[C@]4 ([H])[C@@H] (CC[C@H] (C (C)C)OS (=O) (O)=O)C) ([H])C[C@@H] (NCCCNCCCCN)CC1. Density: 1.13±0.1 g/cm³. Catalog: ACM148717902. | |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson , s disease mouse models [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine | Squalamine is a naturally derived broad-spectrum antibiotic that is predominantly derived from the livers of dogfish and other shark species. Squalamine is undergoing trials for treatment of non-small cell lung cancer (stage I/IIA) as well as general phase I pharmacokinetic studies. In 2005, the Food and Drug Administration granted squalamine Fast Track status for approval for treatment of age-related macular degeneration. However, the Genaera Corporation, the company that has done the most work with squalamine, discontinued trials for its use in treating prostate cancer and wet age-related macular degeneration in 2007. The Squalamine project was acquired by Ohr Pharmaceutical from the now liquidated Genaera, with the prospect of continuing the development of this drug to treat wet age-related macular degeneration. Synonyms: MSI 1256; MSI-1256; MSI1256. Grades: ≥98% (HPLC). CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 627.96. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark. Group: Marine natural products. Alternative Names: Evizon. CAS No. 320725-47-1. Mole weight: 718. Purity: 95%+. IUPACName: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate;(2S)-2-hydroxypropanoic acid. Canonical SMILES: CC (C)C (CCC (C)C1CCC2C1 (CCC3C2C (CC4C3 (CCC (C4)NCCCNCCCCN)C)O)C)OS (=O) (=O)O. CC (C (=O)O)O. Catalog: ACM320725471. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | 100g Pack Size. Group: Building Blocks, Organics. Formula: [(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2]2. CAS No. 111-01-3. Prepack ID 13053317-100g. Molecular Weight 422.81. See USA prepack pricing. |  |
| Squalane | Squalane. Group: Biochemicals. Alternative Names: 2,6,10,15,18,23-Hexamethyltetracosane. Grades: Highly Purified. CAS No. 111-01-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C30H62. US Biological Life Sciences. | Worldwide |
| Squalane | Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 111-01-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7113. | |
| Squalane | United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; hydrocarbons & petrochemicals; european pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosane, perhydrosqualene,Squalane. CAS No. 111-01-3. Pack Sizes: 500MG. IUPAC Name: 2,6,10,15,19,23-hexamethyltetracosane. Molecular Formula: C30H62. Mole Weight: 422.81. Catalog: APS111013. SMILES: CC (C)CCCC (C)CCCC (C)CCCCC (C)CCCC (C)CCCC (C)C. Format: Neat. |  |
| Squalane | Squalane is commonly used as an emollient and moisturizer. Synonyms: 2,6,10,15,19,23-hexamethyltetracosane. CAS No. 111-01-3. Molecular formula: C30H62. Mole weight: 422.81. | |
| Squalane-d62 | Isotope labelled Squalane is used as an emollient and moisturizer in cosmetic applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 16514-83-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C30D62, Molecular Weight: 485.2. US Biological Life Sciences. | Worldwide |
| Squalane Light | 100% plant-based emollient (synonym: hemisqualane) derived from plant sugars (sugar cane) that is a perfect alternative for petroleum-based paraffins and silicone ingredients. It has a great sensorial profile providing unique qualities providing a very light and dry feel. Density 0.76, viscosity 3cps. Uses: All kinds of skin care products, hair conditioners, lip balms, lip sticks, makeup. Group: Cationic surfactants & conditioning agents. CAS No. 3891-98-3/64741-76-0. Appearance: Light yellowish liquid, plain odor. Catalog: CI-HC-0058. | |
| SQUALANE OIL | Synonyms: SQUALANE OIL. CAS No. 59030-00-1. | |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| Squalene | Terpenoids. Alternative Names: Trans-squalene. CAS No. 111-02-4. Molecular formula: C30H50. Mole weight: 410.72. Appearance: Light yellow liquid. Purity: 0.95. IUPACName: (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene. Canonical SMILES: CC (=CCCC (=CCCC (=CCCC=C (C)CCC=C (C)CCC=C (C)C)C)C)C. Density: 0.858 g/mL at 25 °C(lit.). Catalog: ACM111024. | |
| Squalene | Squalene Inhibitor. Uses: Scientific use. Product Category: T4749. CAS No. 111-02-4. |  |
| Squalene | Squalene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Squalene | Squalene - Product ID: NST-10-137. Category: Triterpens. Alternative Names: (E,E,E,E)-Squalene, all-trans-Squalene, Spinacen, Squalen, trans-Squalene. Purity: 98%. Test method: GC. CAS No. 111-02-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Colourless to light yellow liquid. Molecular formula: C30H50. Mole weight: 410.7. Storage: +2 +8 °C. |  |
| Squalene 2,3:22,23-Dioxide | Squalene 2,3:22,23-Dioxide is formed from he epoxidation of 2,3-oxidosqualene, by squalene epoxidase. Squalene 2,3:22,23-Dioxide is accumulated intracellularly during the inhibition of cholesterol biosynthesis in Chinese hamster ovary cells. Group: Biochemicals. Alternative Names: 2,3:22,23-Dioxidosqualene; Squalene 2,3:22,23-Diepoxide; (all-E)-2,3:22,23-Diepoxy-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene; 2,2'-(3,7,12,16-Tetramethyl-3,7,11,15-octadecatetraene-1,18-diyl)bis[3,3-dimethyl-oxirane]. Grades: Highly Purified. CAS No. 31063-19-1. Pack Sizes: 25mg. Molecular Formula: C30H50O2, Molecular Weight: 442.72. US Biological Life Sciences. | Worldwide |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. |  |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| squalene methyltransferase | Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form. Group: Enzymes. Synonyms: TMT-1; TMT-2. Enzyme Commission Number: EC 2.1.1.262. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1867; squalene methyltransferase; EC 2.1.1.262; TMT-1; TMT-2. Cat No: EXWM-1867. | |
| squalene monooxygenase | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Enzyme Commission Number: EC 1.14.14.17. CAS No. 9029-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0914; squalene monooxygenase; EC 1.14.14.17; 9029-62-3; squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Cat No: EXWM-0914. | |
| Squalene (Standard) | Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 111-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214R. | |
| squalene synthase | This microsomal enzyme catalyses the first committed step in the biosynthesis of sterols. The enzyme from yeast requires either Mg2+ or Mn2+ for activity. In the absence of NAD(P)H, presqualene diphosphate (PSPP) is accumulated. When NAD(P)H is present, presqualene diphosphate does not dissociate from the enzyme during the synthesis of squalene from farnesyl diphosphate (FPP). High concentrations of FPP inhibit the production of squalene but not of PSPP. Group: Enzymes. Synonyms: farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Enzyme Commission Number: EC 2.5.1.21. CAS No. 9077-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2758; squalene synthase; EC 2.5.1.21; 9077-14-9; farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Cat No: EXWM-2758. | |
| Squalestatin A | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grades: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73. | |
| Squalestatin B | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70. | |
| Squalestatin C | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50. | |
| Squamatic acid | Synonyms: Squamatsaure; 2-Hydroxy-4-methoxy-6-methyl-1,3-benzenedicarboxylic acid 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 2-Oxy-6-methoxy-4-methyl-isophthalsaeure-3-(3-oxy-2,5-dimethyl-4-carboxy-phenylester). CAS No. 569-36-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Squaric Acid | Crystalline, purity 99+%. Synonyms: 3,4-Dihydroxy-3-cyclobutene-1,2-dione. CAS No. 2892-51-5. Pack Sizes: 10g, 50g. Product ID: FR-0532. M.P. >300. Mole weight: 114.06. |  Frinton Laboratories |
| Squarunkin A hydrochloride | Squarunkin A is an inhibitor of UNC119 chaperone protein-cargo interaction. It inhibits the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A with an IC50 value of 10?nm. It binds to UNC119 proteins in cell lysate and interferes with the activation of Src kinase. Synonyms: Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 2253744-55-5. Molecular formula: C25H32F3N5O4·HCl. Mole weight: 560.01. | |
| Squaw Vine Powder | Squaw Vine Powder. |  CA, FL & NJ |
| SR-01000946410 | SR-01000946410 is a structural analog of PGE2 and a selective agonist for the EP2 receptor subtype. It binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor. It does not bind appreciably to any of the other murine EP receptors. BIt has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4979. Grades: ≥98%. CAS No. 69685-22-9. Molecular formula: C24H40O5. Mole weight: 408.6. | |
| SR 0987 | SR 0987 is a T cell-specific RORγ (RORγt) agonist (EC50 = 800 nM in a gene reporter assay) that induces IL-17 expression and decreases PD-1 expression in T cells in vitro. Synonyms: SR-0987; SR0987; SR 0987; 2-Chloro-N-[4-[2, 2, 2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl]phenyl]benzamide. Grades: ≥98% by HPLC. CAS No. 303126-97-8. Molecular formula: C16H10ClF6NO2. Mole weight: 397.7. | |
| SR-0987 | SR0987 is a RORγt agonist with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1. Group: Fluorinated apis. Alternative Names: 2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide. CAS No. 303126-97-8. Molecular formula: C16H10ClF6NO2. Mole weight: 397.7. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2-chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide. Catalog: OFC303126978. | |
| SR1001 | Retinoic-acid-receptor-related orphan receptors (ROR) α and γ play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist at these receptors. SR 1001 has been shown to suppress IL-17 promoter driven transcriptional activity by inhibiting the interaction of co-activators such as TRAP220 nuclear receptor box 2 peptide (IC50 = 117 nM) and SRC2 with RORα and RORγ as well as by increasing the recruitment of corepressors such as NCoR. At 5 μM, SR 1001 inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs. A 25 mg/kg dose of SR 1001 twice/day delays the onset and the severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Synonyms: SR 1001; SR-1001. Grades: >98%. CAS No. 1335106-03-0. Molecular formula: C15H13F6N3O4S2. Mole weight: 477.4. | |
| SR1001 | SR1001 is a selective ROR α and ROR γt inverse agonist with K i s 172 and 111 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR 10067 | SR 10067 is a selective and cell-permeable Rev-Erbα/β agonist (IC50 = 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively). SR 10067 has no significant activity against a wide range of nuclear receptors, other receptors, ion channels and transporters at 20 μM. SR 10067 has effects of increasing wakefulness, reducing REM and slow wave sleep in vivo. Synonyms: SR 10067; SR-10067; SR-10067; [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone. Grades: ≥98% by HPLC. CAS No. 1380548-02-6. Molecular formula: C31H31NO3. Mole weight: 465.58. | |
| SR1078 | SR 1078 is a selective agonist of RORα and RORγ that stimulates ROR transcriptional activity in HEK293 cell reporter assays. Synonyms: SR 1078; SR-1078. Grades: >98%. CAS No. 1246525-60-9. Molecular formula: C17H10F9NO2. Mole weight: 431.25. | |
| SR 11023 | SR 11023 is an orally active antagonist of PPAR γ, with the IC 50 value of 109 nM that plays an important role in diabetic research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820602-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160162. | |
| SR 11237 | SR 11237. Group: Biochemicals. Grades: Purified. CAS No. 146670-40-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 11237 | SR 11237 is a pan retinoid X receptor (RXR) agonist with no RAR activity. Synonyms: SR12813; SR 12813; SR-12813. 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid. Grades: ≥98% by HPLC. CAS No. 146670-40-8. Molecular formula: C24H28O4. Mole weight: 380.48. | |
| SR 11302 | SR 11302 is an inhibitor of activator protein-1 (AP-1), which is a transcription factor activity that displays antitumor effects in vivo. SR 11302 does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50 > 1 μM for RARα, RARβ, RARγ and RXRα). Synonyms: SR 11302; SR11302; SR-11302; (E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Grades: ≥98% by HPLC. CAS No. 160162-42-5. Molecular formula: C26H32O2. Mole weight: 376.54. | |
| SR 11302 | SR 11302. Group: Biochemicals. Grades: Purified. CAS No. 160162-42-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302. CAS No: 160162-42-5 |  Sarchem Laboratories New Jersey NJ |
| SR121566A | SR121566A, a non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, has been shown to block platelet aggregation induced by a wide variety of agonists including HIT serum/heparin, reduced in a dose-dependent manner the HIT serum/heparin-induced, platelet mediated expression and release of the above mentioned proteins. Synonyms: 3-[[1-(carboxymethyl)piperidin-4-yl]-[4-(4-methanehydrazonoylphenyl)-1,3-thiazol-2-yl]amino]propanoic acid; CTK0H1193; 1-Piperidineaceticacid, 4-[[4-[4-(aminoiminomethyl)phenyl]-2-thiazolyl](2-carboxyethyl)amino]-. CAS No. 180144-61-0. Molecular formula: C20H25N5O4S. Mole weight: 431.51. | |
| SR12813 | SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase , with an IC 50 value of 0.85 μM [1] [2]. SR12813 is also an efficient agonist of human pregnane X receptor ( hPXR ). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW 485801. CAS No. 126411-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100793. | |
| SR 12813 | SR 12813. Group: Biochemicals. Grades: Purified. CAS No. 126411-39-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 12813 | SR 12813 is a pregnane X receptor (PXR) agonist (EC50 = 200 and 700 nM for human and rabbit PXR, respectively) that activates the farnesoid X receptor (FXR) at μM concentrations. SR 12813 exhibits hypocholesterolaemic activity via enhancing the degradation of HMG-CoA reductase. Synonyms: SR 12813; SR12813; SR-12813; [[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid tetraethyl ester; 4-[2,2-bis(diethoxyphosphoryl)ethenyl]-2,6-ditert-butylphenol. Grades: ≥99% by HPLC. CAS No. 126411-39-0. Molecular formula: C24H42O7P2. Mole weight: 504.53. | |
| SR13668 | SR13668 is an Akt inhibitor, is also an orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic and antiangiogenic activities. Akt inhibitor SR13668 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation, and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: SR 13668; SR-13668; 2,10-dicarbethoxy-6-methoxy-5,7-dihydro-indolo[2,3-b]carbazole. CAS No. 637774-61-9. Molecular formula: C25H22N2O5. Mole weight: 430.46. | |
| SR 13800 | SR 13800 is a potent MCT1 inhibitor (IC50 = 0.5 nM). SR 13800 was shown to inhibit proliferation of Raji lymphoma cells in vitro and suppress lactate uptake in breast cancer cells in vitro. Synonyms: SR13800; SR-13800; SR 13800; 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one; 5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)pyrrolo[3,4-d]pyridazin-4-one. Grades: ≥98% by HPLC. CAS No. 227321-12-2. Molecular formula: C25H29N3O2S. Mole weight: 435.58. | |
| SR 140333 | SR 140333 is a potent NK1 receptor antagonist (Ki = 0.74 nM. IC50 = 1.6 nM). SR 140333 inhibits substance P-invoked calcium mobilization and outward current (IC50 = 1.3 nM), and suppresses NK1-mediated nitric oxide-dependent vasodilation in vivo. Synonyms: SR 140333; SR 140,333; SR 140333A; 1-[2-[(3S)-3-(3,4-Dichlorophenyl)-1-[2-[3-(1-methylethoxy)phenyl]acetyl]-3-piperidinyl]ethyl]-4-phenyl-1-azoniabicyclo[2.2.2]octane chloride. Grades: ≥97% by HPLC. CAS No. 153050-21-6. Molecular formula: C37H45Cl3N2O2. Mole weight: 656.12. | |
| SR 140333 | SR 140333. Group: Biochemicals. Grades: Purified. CAS No. 153050-21-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 141716A | SR 141716A. Group: Biochemicals. Grades: Purified. CAS No. 158681-13-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948. Group: Biochemicals. Grades: Purified. CAS No. 184162-64-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor ( NT ) antagonist with IC 50 s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| SR142948A | SR142948A is an antagonist of non-peptide neurotensin (NT) receptor with a high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). SR142948A has the effect of inhibiting bile acid secretion and some stimulant drugs. Uses: An antagonist of non-peptide neurotensin (nt) receptor with an effect of bile acid secretion inhibition. Synonyms: SR 142948; SR 142948A; CHEMBL2431105; CHEMBL 2431105; CHEMBL-2431105; AC1NSKNX. Grades: ≥98 %. CAS No. 184162-64-9. Molecular formula: C39H51N5O6. Mole weight: 685.86. | |
| SR 142948A | SR 142948A is a non-peptide neuropeptide neuropeptin ( NT ) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-21-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124767. | |
| SR 144528 | SR 144528. Group: Biochemicals. Alternative Names: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1, 3, 3-trimethylbicyclo[2. 2. 1]hept-2-yl)-1H-Pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. Molecular Formula: C29H34ClN3O, Molecular Weight: 476.05. US Biological Life Sciences. | Worldwide |
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