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| Product | Description | |
|---|---|---|
| Soy Lecithin Powder 20% PhosphatidylCholine | Soy Lecithin Powder 20% PhosphatidylCholine. |  CA, FL & NJ |
| Soy PC (20%) | Soy PC (20%). Group: Others. L-α-phosphatidylcholine, 20% (Soy) (Soy Total Lipid Extract); Soy PC (20%). Cat No: PHOZ-247. |  |
| Soy PC (40%) | Soy PC (40%). Group: Others. L-α-phosphatidylcholine (Soy-40%); Soy PC (40%). Cat No: PHOZ-246. | |
| Soy protein | Soy protein is a protein that is isolated from soybean. Soya protein is made from soybean meal that has been dehulled and defatted. Dehulled and defatted soybeans are processed into three kinds of high protein commercial products.Soy protein is a vegetable protein. Amino acid composition of soybean protein and milk protein is similar, in addition to methionine slightly lower, the rest of the essential amino acid content are more abundant, is a plant of the full protein, in nutritional value, can be equated with animal protein, the gene structure is also the most close to human amino acids, so it is the most nutritious vegetable protein. Applications: 1. it can be used to raise the yield of meat products.2. it can be added to such solid drinks as oatmeal, coffee mate, soy milk powder peanut milk powder, cocoa milk powder, walnut milk powder, fermented yogurt, juice milk powder, etc. 3. it can also be added to cold drinks (such as ice cream) to reduce the production costs. Group: Others. Appearance: Light yellow powder. Soy protein. Cat No: EXTC-218. | |
| Soy Protein Isolate Food Grade | Soy Protein Isolate Food Grade. | CA, FL & NJ |
| SP 100030 | SP 100030 is a potent dual inhibitor of NF-κB and AP-1 transcriptional activity (IC50 = 50 nM). SP 100030 blocks production of IL-2, IL-8 and TNF-α from Jurkat T cells. It inhibits cytokine production selectively in T cells and exhibits minimal inhibitory effects on cytokine production in other cell types. Synonyms: SP-100030; SP 100030; SP100030; N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide. Grades: ≥99% by HPLC. CAS No. 154563-54-9. Molecular formula: C14H5ClF9N3O. Mole weight: 437.65. |  |
| SP 100030 | SP 100030. Group: Biochemicals. Grades: Purified. CAS No. 154563-54-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SP 141 | SP 141. Group: Biochemicals. Grades: Purified. CAS No. 1253491-42-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SP 141 | SP 141 is a cell-permeable and high affinity MDM2 inhibitor (Ki = 28 nM). SP 141 directly binds MDM2 to inhibit MDM2 expression and induce MDM2 autoubiquitination aw well as proteasomal degradation. SP 141 has been shown to attenuate growth of breast cancer xenograft tumors. Synonyms: SP-141; SP 141; SP141; 6-Methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole. Grades: ≥98% by HPLC. CAS No. 1253491-42-7. Molecular formula: C22H16N2O. Mole weight: 324.38. | |
| SP-141 | SP-141 is a specific inhibitor of MDM2. SP-141 promotes MDM2 auto-ubiquitination and degradation. SP-141 might be used for the research of pancreatic cancer and breast cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253491-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110182. |  |
| SP187 | SP187, also known as N-9-DNJ and UV-4B, is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo and used to treat dengue fever and influenza infection. Synonyms: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol; N-9-Methoxynonyldeoxynojirimycin; SP-187; SP187; SP 187; N-9-DNJ; UV-4B; N9DNJ; UV4B; N 9 DNJ; UV 4B. Grades: 99.30%. CAS No. 615253-61-7. Molecular formula: C16H33NO5. Mole weight: 319.44. | |
| SP187 | SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MON-DNJ; UV4. CAS No. 615253-61-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00160. | |
| SP-187 HCl | SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SP-187 HCl; SP-187 hydrochloride SP-187; SP187; SP 187; N-9-DNJ; UV-4B; N9DNJ; UV4B; N 9 DNJ; UV 4B; Iminosugar UV 4; MON-DNJ; N-9-Methoxynonyldeoxynojirimycin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1333144-07-2. Molecular formula: C16H34ClNO5. Mole weight: 355.9. Purity: >98%. IUPACName: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol hydrochloride. Canonical SMILES: O[C@@H]1[C@@H](CO)N(CCCCCCCCCOC)C[C@H](O)[C@H]1O.[H]Cl. Product ID: ACM1333144072. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Sp1 (GC-box binding protein), GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| Sp-2',3'-cAMPS | Sp-2',3'-cAMPS is a crucial cyclic nucleotide analog acting as an activator of protein kinase A (PKA), enabling the study of its role in signal transduction pathways. This product is widely used in biomedical field research to investigate the modulation of PKA activity and its implications in various drug responses and diseases involving cAMP-dependent signaling pathways. Synonyms: Adenosine- 2', 3'- cyclic monophosphorothioate, exo / Sp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 118276-00-9. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3. | |
| SP2509 | SP2509 inhibits the association of LSD1 with CoREST, increases promoter-specific H3K4Me3 and induces p53, p21 and C/EBP&alpha. SP2509 also significantly inhibits the colony growth and induces apoptosis of OCI-AML3. Synonyms: HCI-2509; SP2509; SP 2509; SP-2509. Grades: >98%. CAS No. 1423715-09-6. Molecular formula: C19H20ClN3O5S. Mole weight: 437.90. | |
| SP2509 | SP2509 is a potent and selective antagonist of lysine specific demethylase 1 (LSD1) with an IC50 of 13 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1423715-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12635. | |
| SP-2509 | LSD1 is a promising target for cancer therapy. Epigenetic control of histone methylation isfrequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer. siRNAknockdown of LSD1 has been shown to suppress growth of cancer cells. SP2509 is a selectiveand reversible LSD1 inhibitor with an IC50 of 10nM. SP2509 demonstrates a high specificity forLSD1, with no effect on MAOi. Group: Biochemicals. Grades: Highly Purified. CAS No. 1423715-09-6. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C19H20ClN3O5S. US Biological Life Sciences. | Worldwide |
| SP27 | SP27 is a PROTAC that can selective degrades PLK4 , with a DC 50 of 19.5 nM. SP27 can be used for the research of breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034805-75-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149324. | |
| Sp-2-AEA-cAMPS | Sp-2-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-2-AEA-cAMPS-Agarose | Sp-2-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose. | |
| Sp-2'-AEC-cAMPS | Sp-2'-AEC-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C13H18N7O6PS. Mole weight: 431.4. | |
| Sp-2'-AEC-cAMPS-Agarose | Sp-2'-AEC-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-2-AHA-cAMPS | Sp-2-AHA-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. It is also a PDE-resistant analogue of 2-AHA-cAMP. Synonyms: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214276-94-5. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-2-AHA-cAMPS-Agarose | Sp-2-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cAMPS | Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- (6- Aminohexyl)carbamoyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O6PS. Mole weight: 487.5. | |
| Sp-2'-AHC-cAMPS-Agarose | Sp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cGMPS | Sp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- (6- Aminohexyl)carbamoylguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 1262749-61-0. Molecular formula: C17H26N7O7PS. Mole weight: 503.5. | |
| Sp-2'-AHC-cGMPS-Agarose | Sp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2-CF3-cBIMPS | Sp-2-CF3-cBIMPS, a research chemical focused on insulin and glucose metabolism, has potential therapeutic benefits for metabolic diseases like diabetes. By activating the AMP-activated protein kinase (AMPK) pathway, it shows that adding a trifluoromethyl group can increase its potency compared to other AMPK activators. With its documented scientific profile, Sp-2-CF3-cBIMPS embodies a unique approach to metabolism research to inspire medical advancements. Synonyms: 2- Trifluoromethyl- 1- β- D- ribofuranosylbenzimidazole- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Molecular formula: C13H11F3N2O5PS · Na. Mole weight: 418.3. | |
| Sp-2-Cl-cAMPS | Sp-2-Cl-cAMPS is an analogue of Sp-cAMPS, the protein kinase A stimulator. The chlorine atom in position 2 of adenine nucleobase significantly increase the stability and lipophilicity. Synonyms: 2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124854-63-3. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-2'-O-MB-cAMPS | Sp-2'-O-MB-cAMPS is a precursor ofSp-cAMPS, a PDE-resistant stimulator of protein kinase A. Sp-cAMPS and butyrate are released after the metabolism of Sp-2'-O-MB-cAMPS by esterases. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 152218-23-0. Molecular formula: C14H17N5O6PS · Na. Mole weight: 437.4. | |
| Sp-2'-O-Me-CTP-α-S | Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Synonyms: 2'- O- Methylcytidine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-01-0. Molecular formula: C10H18N3O13P3S (free acid). Mole weight: 513.3 (free acid). | |
| Sp-2'-O-Me-GTP-α-S | Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Synonyms: 2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-02-1. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
| SP-420 | SP-420 is a desferrithiocin analogue with iron-clearing efficiency. Its ICE value is 26.7. It is more potent than desferrithiocin. Uses: Sp-420 has iron-clearing effect. Synonyms: SP-420; SP420; SP 420; (4S)-4,5-Dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic acid. Grades: >98%. CAS No. 911714-45-9. Molecular formula: C16H21NO6S. Mole weight: 355.41. | |
| SP-471 | SP-471 is a potent dengue virus (DENV) protease inhibitor with IC 50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768010-39-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144646. | |
| Sp-5,6-DCl-cBIMPS | Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-cAMP in stability, membrane permeability and potency. Synonyms: 5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 120912-54-1. Molecular formula: C12H10Cl2N2O5PS · Na. Mole weight: 419.2. | |
| Sp-5,6-dichloro-cBIMPS sodium salt | Sp-5,6-dichloro-cBIMPS is a potent and selective activator of protein kinase A (PKA). Sp-5,6-dichloro-cBIMPS is also resistant to degradation by cyclic nucleotide phosphodiesterases. Synonyms: Sp-5,6-DCI-cBIMPS; 5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt. Grades: ≥99%. CAS No. 142439-96-1. Molecular formula: C12H10Cl2N2O5PS·Na. Mole weight: 419.1. | |
| SP600125 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SP600125 | SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129-56-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12041. | |
| SP600125 | SP-600125 is a specific JNK inhibitor. SP600125 kills p53-deficient cells more efficiently than their p53-proficient counterparts, in vitro. Similar observations were obtained in vivo, in mice carrying p53-deficient and -proficient human xenografts. Synonyms: SP600125; SP 600125; SP-600125. Grades: 0.98. CAS No. 129-56-6. Molecular formula: C14H8N2O. Mole weight: 220.231. | |
| SP 600125 | SP 600125. Group: Biochemicals. Grades: Purified. CAS No. 129-56-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sp-6-AE-cAMPS | Sp-6-AE-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C12H17N6O5PS. Mole weight: 388.4. | |
| Sp-6-AE-cAMPS-Agarose | Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-AH-cAMPS | Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C16H25N6O5PS. Mole weight: 444.5. | |
| Sp-6-AH-cAMPS-Agarose | Sp-6-AH-cAMPS-Agarose is the Sp-cAMPS immobilized on agarose by an aminohexyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-Bnz-cAMPS | Sp-6-Bnz-cAMPS is a selective and PDE-resistant stimulator of cAMP-dependent protein kinase, which can be used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 152218-18-3. Molecular formula: C17H15N5O6PS · Na. Mole weight: 471.4. | |
| Sp-6-Cl-cPuMPS | Sp-6-Cl-cPuMPS is a PDE-resistant activator of protein kinase A that can be modified in position 6. Synonyms: 6- Chloropurine riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 129693-12-5. Molecular formula: C10H9ClN4O5PS · Na. Mole weight: 386.7. | |
| Sp-6-Phe-cAMPS | Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 169335-92-6. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4. | |
| Sp-8-AEA-cAMPS | Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-84-3. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-8-AEA-cAMPS-Agarose | Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-8-AET-cGMPS | Sp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-92-3. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4. | |
| Sp-8-AET-cGMPS-Agarose | Sp-8-AET-cGMPS-Agarose is the protein kinase G activator Sp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-AHA-cAMPS | Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-03-4. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-8-AHA-cAMPS-Agarose | Sp-8-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-BnT-2'-O-Me-cAMPS / "S-223" | Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-cAMPS does not induce Epac signalling at 100 μM possibly for inefficient cellular uptake in this biosystem. Synonyms: 8- Benzylthio- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O5PS2 · Na. Mole weight: 503.5. | |
| Sp-8-BnT-cAMPS / "S-220" | Sp-8-BnT-cAMPS is an exceptional stimulant targeting protein kinase A (PKA) with remarkable precision. While S-220 is an exquisite synthetic compound with antimicrobial prowess. Synonyms: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H17N5O5PS2 · Na. Mole weight: 489.5. | |
| Sp-8-Br-2'-O-Me-cAMPS | Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-34-7. Molecular formula: C11H12BrN5O5PS · Na. Mole weight: 460.2. | |
| Sp-8-Br-cAMPS | Sp-8-Br-cAMPS is a resistant activator of protein kinase A, the cAMP agonist. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 127634-20-2. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2. | |
| Sp-8-Br-cAMPS-AM | Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br-cAMPS-AM by esterases. Synonyms: 8- Bromoadenosine- 3', 5'- monophosphorothioate, acetoxymethyl ester, Sp- isomer ( Sp-8-Br-cAMPS-AM ). Grades: ≥ 97% by HPLC for mixture of the axial and equatorial isomer. Molecular formula: C13H15BrN5O7PS. Mole weight: 496.2. | |
| Sp-8-Br-cGMPS | Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to cGMP or Sp-cGMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-03-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2. | |
| Sp-8-Br-PET-cGMPS | Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I α and I ß (cGMP agonist), which is used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-21-2. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3. | |
| Sp-8-Cl-cAMPS | Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant properties. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Sp- isomer. Grades: ≥ 99% by HPLC. CAS No. 142754-28-7. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-8-CPT-cAMPS | Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129693-13-6. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8. | |
| Sp-8-OH-cAMPS | Sp-8-OH-cAMPS is a polar analogue of Sp-cAMPS, the protein kinase A activator, with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. It can be used for the study of extracellular cAMP receptors. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 749843-87-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3. | |
| Sp-8-pCPT-2'-O-Me-cAMPS | Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more lipophilic and membrane permeant. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-37-0. Molecular formula: C17H16ClN5O5PS2 · Na. Mole weight: 523.9. | |
| Sp-8-pCPT-cGMPS | Sp-8-pCPT-cGMPS is a stimulator of protein kinase G type I α and type II with superior membrane permeability and stability. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 160385-87-5. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9. | |
| Sp-8-pCPT-PET-cGMPS | Sp-8-pCPT-PET-cGMPS is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Sp-8-Br-PET-cGMPS, Sp-8-pCPT-PET-cGMPS is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-63-2. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626. | |
| Sp-8-PIP-cAMPS | Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 156816-35-2. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4. | |
| SPA0355 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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