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| Product | Description | |
|---|---|---|
| Sp-2'-AEC-cAMPS | Sp-2'-AEC-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C13H18N7O6PS. Mole weight: 431.4. |  |
| Sp-2'-AEC-cAMPS-Agarose | Sp-2'-AEC-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-2-AHA-cAMPS | Sp-2-AHA-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. It is also a PDE-resistant analogue of 2-AHA-cAMP. Synonyms: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214276-94-5. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-2-AHA-cAMPS-Agarose | Sp-2-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cAMPS | Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- (6- Aminohexyl)carbamoyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O6PS. Mole weight: 487.5. | |
| Sp-2'-AHC-cAMPS-Agarose | Sp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cGMPS | Sp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- (6- Aminohexyl)carbamoylguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 1262749-61-0. Molecular formula: C17H26N7O7PS. Mole weight: 503.5. | |
| Sp-2'-AHC-cGMPS-Agarose | Sp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2-CF3-cBIMPS | Sp-2-CF3-cBIMPS, a research chemical focused on insulin and glucose metabolism, has potential therapeutic benefits for metabolic diseases like diabetes. By activating the AMP-activated protein kinase (AMPK) pathway, it shows that adding a trifluoromethyl group can increase its potency compared to other AMPK activators. With its documented scientific profile, Sp-2-CF3-cBIMPS embodies a unique approach to metabolism research to inspire medical advancements. Synonyms: 2- Trifluoromethyl- 1- β- D- ribofuranosylbenzimidazole- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Molecular formula: C13H11F3N2O5PS · Na. Mole weight: 418.3. | |
| Sp-2-Cl-cAMPS | Sp-2-Cl-cAMPS is an analogue of Sp-cAMPS, the protein kinase A stimulator. The chlorine atom in position 2 of adenine nucleobase significantly increase the stability and lipophilicity. Synonyms: 2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124854-63-3. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-2'-O-MB-cAMPS | Sp-2'-O-MB-cAMPS is a precursor ofSp-cAMPS, a PDE-resistant stimulator of protein kinase A. Sp-cAMPS and butyrate are released after the metabolism of Sp-2'-O-MB-cAMPS by esterases. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 152218-23-0. Molecular formula: C14H17N5O6PS · Na. Mole weight: 437.4. | |
| Sp-2'-O-Me-CTP-α-S | Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Synonyms: 2'- O- Methylcytidine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-01-0. Molecular formula: C10H18N3O13P3S (free acid). Mole weight: 513.3 (free acid). | |
| Sp-2'-O-Me-GTP-α-S | Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Synonyms: 2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-02-1. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
| SP-420 | SP-420 is a desferrithiocin analogue with iron-clearing efficiency. Its ICE value is 26.7. It is more potent than desferrithiocin. Uses: Sp-420 has iron-clearing effect. Synonyms: SP-420; SP420; SP 420; (4S)-4,5-Dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic acid. Grades: >98%. CAS No. 911714-45-9. Molecular formula: C16H21NO6S. Mole weight: 355.41. | |
| SP-471 | SP-471 is a potent dengue virus (DENV) protease inhibitor with IC 50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768010-39-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144646. |  |
| Sp-5,6-DCl-cBIMPS | Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-cAMP in stability, membrane permeability and potency. Synonyms: 5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 120912-54-1. Molecular formula: C12H10Cl2N2O5PS · Na. Mole weight: 419.2. | |
| Sp-5,6-dichloro-cBIMPS sodium salt | Sp-5,6-dichloro-cBIMPS is a potent and selective activator of protein kinase A (PKA). Sp-5,6-dichloro-cBIMPS is also resistant to degradation by cyclic nucleotide phosphodiesterases. Synonyms: Sp-5,6-DCI-cBIMPS; 5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt. Grades: ≥99%. CAS No. 142439-96-1. Molecular formula: C12H10Cl2N2O5PS·Na. Mole weight: 419.1. | |
| SP600125 | SP-600125 is a specific JNK inhibitor. SP600125 kills p53-deficient cells more efficiently than their p53-proficient counterparts, in vitro. Similar observations were obtained in vivo, in mice carrying p53-deficient and -proficient human xenografts. Synonyms: SP600125; SP 600125; SP-600125. Grades: 0.98. CAS No. 129-56-6. Molecular formula: C14H8N2O. Mole weight: 220.231. | |
| SP 600125 | SP 600125. Group: Biochemicals. Grades: Purified. CAS No. 129-56-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Sp-6-AE-cAMPS | Sp-6-AE-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C12H17N6O5PS. Mole weight: 388.4. | |
| Sp-6-AE-cAMPS-Agarose | Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-AH-cAMPS | Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C16H25N6O5PS. Mole weight: 444.5. | |
| Sp-6-AH-cAMPS-Agarose | Sp-6-AH-cAMPS-Agarose is the Sp-cAMPS immobilized on agarose by an aminohexyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-Bnz-cAMPS | Sp-6-Bnz-cAMPS is a selective and PDE-resistant stimulator of cAMP-dependent protein kinase, which can be used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 152218-18-3. Molecular formula: C17H15N5O6PS · Na. Mole weight: 471.4. | |
| Sp-6-Cl-cPuMPS | Sp-6-Cl-cPuMPS is a PDE-resistant activator of protein kinase A that can be modified in position 6. Synonyms: 6- Chloropurine riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 129693-12-5. Molecular formula: C10H9ClN4O5PS · Na. Mole weight: 386.7. | |
| Sp-6-Phe-cAMPS | Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 169335-92-6. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4. | |
| Sp-8-AEA-cAMPS | Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-84-3. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-8-AEA-cAMPS-Agarose | Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-8-AET-cGMPS | Sp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-92-3. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4. | |
| Sp-8-AET-cGMPS-Agarose | Sp-8-AET-cGMPS-Agarose is the protein kinase G activator Sp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-AHA-cAMPS | Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-03-4. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-8-AHA-cAMPS-Agarose | Sp-8-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-BnT-2'-O-Me-cAMPS / "S-223" | Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-cAMPS does not induce Epac signalling at 100 μM possibly for inefficient cellular uptake in this biosystem. Synonyms: 8- Benzylthio- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O5PS2 · Na. Mole weight: 503.5. | |
| Sp-8-BnT-cAMPS / "S-220" | Sp-8-BnT-cAMPS is an exceptional stimulant targeting protein kinase A (PKA) with remarkable precision. While S-220 is an exquisite synthetic compound with antimicrobial prowess. Synonyms: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H17N5O5PS2 · Na. Mole weight: 489.5. | |
| Sp-8-Br-2'-O-Me-cAMPS | Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-34-7. Molecular formula: C11H12BrN5O5PS · Na. Mole weight: 460.2. | |
| Sp-8-Br-cAMPS | Sp-8-Br-cAMPS is a resistant activator of protein kinase A, the cAMP agonist. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 127634-20-2. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2. | |
| Sp-8-Br-cAMPS-AM | Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br-cAMPS-AM by esterases. Synonyms: 8- Bromoadenosine- 3', 5'- monophosphorothioate, acetoxymethyl ester, Sp- isomer ( Sp-8-Br-cAMPS-AM ). Grades: ≥ 97% by HPLC for mixture of the axial and equatorial isomer. Molecular formula: C13H15BrN5O7PS. Mole weight: 496.2. | |
| Sp-8-Br-cGMPS | Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to cGMP or Sp-cGMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-03-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2. | |
| Sp-8-Br-PET-cGMPS | Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I α and I ß (cGMP agonist), which is used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-21-2. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3. | |
| Sp-8-Cl-cAMPS | Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant properties. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Sp- isomer. Grades: ≥ 99% by HPLC. CAS No. 142754-28-7. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-8-CPT-cAMPS | Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129693-13-6. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8. | |
| Sp-8-OH-cAMPS | Sp-8-OH-cAMPS is a polar analogue of Sp-cAMPS, the protein kinase A activator, with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. It can be used for the study of extracellular cAMP receptors. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 749843-87-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3. | |
| Sp-8-pCPT-2'-O-Me-cAMPS | Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more lipophilic and membrane permeant. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-37-0. Molecular formula: C17H16ClN5O5PS2 · Na. Mole weight: 523.9. | |
| Sp-8-pCPT-cGMPS | Sp-8-pCPT-cGMPS is a stimulator of protein kinase G type I α and type II with superior membrane permeability and stability. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 160385-87-5. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9. | |
| Sp-8-pCPT-PET-cGMPS | Sp-8-pCPT-PET-cGMPS is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Sp-8-Br-PET-cGMPS, Sp-8-pCPT-PET-cGMPS is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-63-2. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626. | |
| Sp-8-PIP-cAMPS | Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 156816-35-2. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4. | |
| SPACE peptide | SPACE peptide is a skin penetrating peptide which can enhance topical delivery of a macromolecule, hyaluronic acid and facilitates the delivery of molecules through the skin. Molecular formula: C40H63N15O17S2. Mole weight: 1090.17. | |
| Spacer C12 CE Phosphoramidite | Spacer phosphoramidites C3, 9, and 18 are used to insert spacer arms in oligonucleotides. When a longer spacer is required, the compound can be added multiple times. Synonyms: 3-[12-[bis (4-methoxyphenyl) -phenylmethoxy]dodecoxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile. Grades: >95% by HPLC. CAS No. 158665-27-1. Molecular formula: C42H61N2O5P. Mole weight: 704.93. | |
| Spacer Phosphoramidite 18 | Spacer phosphoramidites 18 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: >95% by HPLC. Molecular formula: C42H61N2O10P. Mole weight: 784.93. | |
| Spacer Phosphoramidite 9 | Spacer phosphoramidites 9 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 9-O-Dimethoxytrityl-triethylene glycol,1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: >95% by HPLC. CAS No. 146668-73-7. Molecular formula: C36H49N2O7P. Mole weight: 652.77. | |
| Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt | Sp-Diastereomer of adenosine 3',5'-cyclic monophosphorothioate is a potent, membrane-permeable activator of PKA (cAMP dependent protein kinase I and II). Mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases. Exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP. Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt hydrate is an activator of Epac. Applications: A membrane permeable activator of camp dependent protein kinase i and ii. Group: Coenzymes. Synonyms: Sp-Cyclic 3',5'-hydrogen phosphorothioate adenosine; Sp-cAMPS triethylammonium salt. CAS No. 93602-66-5. Purity: ≥98%. Mole weight: 446.46. Form: Solid. Sp-Cyclic 3',5'-hydrogen phosphorothioate adenosine; Sp-cAMPS triethylammonium salt; Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt; 93602-66-5. Cat No: COEC-116. |  |
| Spadin | Spadin is a potent and brain penetrating TREK-1 channel blocker (IC50 = 71 nM) displaying antidepressant activity. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis in adult mice. Synonyms: Spadin; 1270083-24-3; Spadin (trifluoroacetate salt); HB5438; AKOS025293510; C96H142N26O22; S-1270083-24-3. CAS No. 1270083-24-3. Molecular formula: C96H142N26O22. Mole weight: 2012.34. | |
| Spadin | Spadin, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with IC 50 value of 10 nM. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis. Spadin can be used for antidepressant research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1270083-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1422. | |
| SPADNS | SPADNS. CAS No. 23647-14-5. |  Pennsylvania PA |
| SPADNS ACS | SPADNS ACS. Group: Biochemicals. Grades: ACS Grade. Pack Sizes: 25g, 100g. US Biological Life Sciences. | Worldwide |
| Spaglumic Acid | Spaglumic Acid is a peptide neurotransmitter and the third-most-prevalent neurotransmitter in the mammalian nervous system. NAAG consists of N-acetylaspartic acid and glutamic acid coupled via a peptide bond. Spaglumic Acid alsp acts as an NMDA receptor activator and mGlu3 receptor agonist. Synonyms: N-Acetyl-L-aspartyl-L-glutamic acid; Isospaglumic acid; NAAG; N-Acetyl-Asp-Glu; N-acetylaspartylglutamate. Grades: ≥96% by HPLC. CAS No. 3106-85-2. Molecular formula: C11H16N2O8. Mole weight: 304.26. | |
| Spaglumic Acid | Spaglumic Acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in brain. Uses: Scientific research. Group: Natural products. Alternative Names: N-Acetylaspartylglutamic acid. CAS No. 3106-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100921. | |
| Spaglumic Acid | Spaglumic Acid. Group: Biochemicals. Alternative Names: N-Acetyl-L-α-aspartyl-L-glutamic Acid; N-(N-Acetyl-L-α-aspartyl)-L-glutamic Acid; Acetyl-α-L-aspartylglutamic Acid; Isospaglumic Acid; N- (N-Acetylaspartyl) glutamic Acid; N-Acetyl-L-aspartyl-L-glutamic Acid; N-Acetyl-α-L-aspartyl-L-glutamic Acid; N-Acetyl-α-aspartylglutamic Acid; N-Acetylaspartylglutamic Acid; NAAG; α-Spaglumic Acid. Grades: Highly Purified. CAS No. 3106-86-2. Pack Sizes: 50mg. Molecular Formula: C11H16N2O8, Molecular Weight: 304.25. US Biological Life Sciences. | Worldwide |
| Spaglumic Acid-d3 | Spaglumic Acid-d3 is the isotope labelled analogue of Spaglumic Acid, a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments. Group: Biochemicals. Alternative Names: N-Acetyl-L-α-aspartyl-L-glutamic Acid-d3; N-(N-Acetyl-L-α-aspartyl)-L-glutamic Acid-d3; Acetyl-α-L-aspartylglutamic Acid-d3; Isospaglumic Acid-d3; N- (N-Acetylaspartyl) glutamic Acid-d3; N-Acetyl-L-aspartyl-L-glutamic Acid-d3; N-Acetyl-α-L-aspartyl-L-glutamic Acid-d3; N-Acetyl-α-aspartylglutamic Acid-d3; N-Acetylaspartylglutamic Acid-d3; NAAG-d3; α-Spaglumic Acid-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Span 20 | Span 20. CAS No. 1338-39-2. Product ID: PE-0040. Molecular formula: C18H34O6. Mole weight: 346.459. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Span 20; PE-0040; C18H34O6; 1338-39-2; 1338-39-2. Appearance: Clear, colorless liquid. Purity: 0.9999. Storage: Keep tightly closed in a cool place in a tightly closed container. Boiling Point: 516.1°C at 760mmHg. Density: 1.032 g/cm3. |  |
| Span 20 | Span 20. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sorbitan monolaurate; Arlasel 20. Product Category: Non-ionic Surfactants. Appearance: Amber oil. CAS No. 1338-39-2. Molecular formula: C18H34O6. Mole weight: 346.46. IUPACName: [2-[(2R,3S,4R)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate. Density: 1.032 g/mL at 25 °C (lit.). ECNumber: 215-663-3. Product ID: ACM1338392. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Span 40 | Span 40. CAS No. 26266-57-9. Product ID: PE-0041. Molecular formula: C22H42O6. Mole weight: 402.6. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Span 40; PE-0041; C22H42O6; 26266-57-9; 26266-57-9. Appearance: Solid. EC Number: 247-568-8. Synonym(s): Sorbitan palmitate. Quality Level: 200. Melting Point: 46-47 °C (lit.). | |
| Span 60 | Sorbitan monostearate is an ester of sorbitan (a sorbitol derivative) and stearic acid and is sometimes referred to as a synthetic wax. It is primarily used as an emulsifier to keep water and oils mixed. Sorbitan monostearate is a non-ionic surfactant with emulsifying, dispersing, and wetting properties. Uses: Sorbitan monooctadecanoate can be used as an excipient, such as emulsifiers, nonionic surfactants, solubilizers, as well as wetting and dispersing/suspending agents. Additional or Alternative Names: Arlacel 60. Product Category: Non-ionic Surfactants. Appearance: White to light yellow powder. CAS No. 1338-41-6. Molecular formula: C24H46O6. Mole weight: 430.62. IUPACName: [2-[(2R,3S,4R)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] octadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)O)O. Density: 1.1±0.1 g/mL. ECNumber: 215-664-9. Product ID: ACM1338416-3. Alfa Chemistry ISO 9001:2015 Certified. | |
| Span 60 | Sorbitan monostearate is an ester of sorbitan (a sorbitol derivative) and stearic acid and is sometimes referred to as a synthetic wax. It is primarily used as an emulsifier to keep water and oils mixed. Sorbitan monostearate is used in the manufacture of food and healthcare products and is a non-ionic surfactant with emulsifying, dispersing, and wetting properties. It is also employed to create synthetic fibers, metal machining fluid, and brighteners in the leather industry, and as an emulsifier in coatings, pesticides, and various applications in the plastics, food and cosmetics industries. CAS No. 1338-41-6. Product ID: PE-0042. Molecular formula: C24H46O6. Mole weight: 430.618. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Span 60; PE-0042; C24H46O6; 1338-41-6; 1338-41-6. Appearance: Cream color flake. EC Number: 215-664-9. Synonym(s): Span(rg 60;Lonzest(R) SMS;ARLACEL 60;SPAN(R) 60;(Sorbitan Monostearate). Storage: Store in a dry, cool and well-ventilated place, away from direct sunlight. Keep containers closed when not in use. Boiling Point: 579ºC at 760 mmHg. Melting Point: 54-57ºC. Density: 1.056 g/cm3. | |
| Span 60 | Span 60. Synonyms: FEMA 3028; EMALEX SPE-100S; ARLACEL 60; SPAN(TM) 60; SPAN 60; SPAN(R) 60; SPAN NO 60; SORBITAN MONOSTEARATE. CAS No. 1338-41-6. Product ID: PE-0014. Molecular formula: C24H46O6. Category: Humectants; Dispersion Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Dispersion Excipients; Span 60; PE-0014; C24H46O6; 1338-41-6; 1338-41-6. Purity: 0.99. Color: Cream colouRed flakes. EC Number: 215-664-9. Physical State: Solid. Solubility: Practically insoluble, but dispersible in water, slightly soluble in alcohol. Storage: Store below 30°C. Boiling Point: 464.84°C (rough estimate). Melting Point: 54-57 °C(lit.). | |
| Span® 65 | Sorbitan tristearate. CAS No. 26658-19-5. Product ID: 8-05103. Molecular formula: C60H114O8. Mole weight: 96.54. Properties: nonionic surfactant. MFCD No. MFCD00151165. |  |
| Span 80 | Span 80. CAS No. 1338-43-8. Product ID: PE-0043. Molecular formula: C24H44O6. Mole weight: 428.603. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Span 80; PE-0043; C24H44O6; 1338-43-8; 1338-43-8. Appearance: Yellow to brown liquid. Purity: 0.9999. Boiling Point: 579.3°C at 760 mmHg. Melting Point: 0.986°C. Density: 0.986 g/cm3. | |
| Span 80 | Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Uses: Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Additional or Alternative Names: Sorbitan monooleate. Product Category: Non-ionic Surfactants. Appearance: Yellow to amber liquid. CAS No. 1338-43-8. Molecular formula: C24H44O6. Mole weight: 428.6. IUPACName: [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] (Z)-octadec-9-enoate. Canonical SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(C1C(C(CO1)O)O)O. Density: 1.1±0.1 g/mL. ECNumber: 215-665-4. Product ID: ACM1338438-3. Alfa Chemistry ISO 9001:2015 Certified. | |
| Span 80 | Span 80. CAS No. 1338-43-8. Product ID: PE-0272. Molecular formula: C24H44O6. Mole weight: 428.603. Category: Ointment Base. Product Keywords: Pharmaceutical Excipients; Semi-solid Dosage Form; Ointment Base; Span 80; PE-0272; C24H44O6; 1338-43-8; 1338-43-8. Appearance: Yellow to brown liquid. Purity: 0.9999. Boiling Point: 579.3°C at 760 mmHg. Melting Point: 0.986°C. Density: 0.986 g/cm3. | |
| Spantide I | Spantide I, a substance P analog, is a selective NK 1 receptor antagonist, with K i values of 230 nM and 8150 nM for NK 1 and NK 2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 91224-37-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1194. | |
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