A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
SRT1720 Hydrochloride. Group: Biochemicals. Alternative Names: N-[2-[3- (1-piperazinylmethyl) imidazo[2, 1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 1001645-58-4. Pack Sizes: 5mg. Molecular Formula: C25H23N7OS xHCl, Molecular Weight: 469.56. US Biological Life Sciences.
Worldwide
SRT 2104
SRT 2104 is a first-in-class, highly selective and brain-permeable activator of the NAD+ dependent deacetylase Sirt1, increases Sirt1 protein, but shows no effect on Sirt1 mRNA. Used in the research of diabetes mellitus and Huntingtons disease[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093403-33-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15262.
SS-208 is a selective HDAC6 inhibitor, with an IC 50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVS100. CAS No. 2245942-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126330.
SS-228Y
SS-228Y is an antibiotic produced by Chainia Sp. It is active against gram-positive bacteria and Ehrlich's ascites carcinoma. Synonyms: Antibiotic SS-228 Y; SS-228 Y. Grade: 95%. CAS No. 56257-16-0. Molecular formula: C19H14O6. Mole weight: 338.31.
SS-56C
SS-56C is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 C. CAS No. 39471-55-1. Molecular formula: C19H35N3O14. Mole weight: 529.5.
SS-56D
SS-56D is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 D. Molecular formula: C19H35N3O13. Mole weight: 513.49.
SSA protein SS-56 (55-64)
A peptide fragment of SSA protein SS-56.
S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE
S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S,S'-BIS-(2-THIENYL)-METHYLENE-DISULPHIDE. Product Category: Heterocyclic Organic Compound. CAS No. 119784-44-0. Molecular formula: C9H8S4. Mole weight: 244.42. Product ID: ACM119784440. Alfa Chemistry ISO 9001:2015 Certified.
s,s'-Diethyl N,N'-hexane-1,6-diylbis(dibutylethylammonium)disulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tetrabutyldiethylhexamethylenediammonium ethylsulfate. Product Category: Heterocyclic Organic Compound. CAS No. 68052-49-3. Molecular formula: C26H58N2.2C2H5O4S. Mole weight: 648.999520 [g/mol]. Purity: 0.96. IUPACName: dibutyl-[6-[dibutyl(ethyl)azaniumyl]hexyl]-ethylazanium; ethyl sulfate. Canonical SMILES: CCCC[N+](CC)(CCCC)CCCCCC[N+](CC)(CCCC)CCCC.CCOS(=O)(=O)[O-].CCOS(=O)(=O)[O-]. ECNumber: 268-327-3. Product ID: ACM68052493. Alfa Chemistry ISO 9001:2015 Certified.
S,S'-dimethyl dithiocarbonate
S,S'-dimethyl dithiocarbonate. Group: Biochemicals. Grades: Highly Purified. CAS No. 868-84-8. Pack Sizes: 500g, 1kg. Molecular Formula: C3H6OS2. US Biological Life Sciences.
Worldwide
S,S-Diphenylsulfilimine Monohydrate
S,S-Diphenylsulfilimine Monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 68837-61-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
Sse9 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of pBR322 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. ↑AATT TTAA&darr. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sse9 I gene from Sporosarcina species. Pack: 10 mM Tis-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1180RE.
S, S'-Ethylenebis (glutathione)
S, S'-Ethylenebis (glutathione) is a haloethane-glutathione conjugate formed via GSH transferases. S, S'-Ethylenebis (glutathione) formation is used to study the polymorphism in glutathione conjugation activity of human erythrocytes towards ethylene dibromide. Group: Biochemicals. Alternative Names: 2,2'-(1,2-Ethanediyl)bis[L-γ-glutamyl-L-cysteinylglycine. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
SSI-4
SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11 C, used as a ligand to in vivo small animal PET/CT imaging of SCD1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1875084-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155033.
SSK1
SSK1, a senescence-specific killing compound, is a ?-galactosidase-targeted proagent attenuates inflammation. SSK1 is activated by lysosomal ?-galactosidase and selectively killed senescent cells through the activation of p38 MAPK and induction of apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2629250-69-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138936.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. AAT↑ATT TTA↓TAA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer K, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene SspI from Sphaerotilus species. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1181RE.
SSR128129E
SSR128129E is an orally available and allosteric FGFR inhibitor with an IC 50 of 1.9 μM for FGFR1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SSR. CAS No. 848318-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15599.
SSR 146977 hydrochloride
SSR 146977 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 264618-38-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SSR180711 hydrochloride
SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR ( K i =22 nM; IC 50 =30 nM) and human α7 n-AChR ( K i =14 nM; IC 50 =18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 446031-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19411.
SSR504734
SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38?nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 615571-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10715.
SSR 69071
SSR 69071. Group: Biochemicals. Grades: Purified. CAS No. 344930-95-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
s,s,s-Csdphen
s,s,s-Csdphen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S,S,S-CsDphen, 676270-65-8. Product Category: Heterocyclic Organic Compound. CAS No. 676270-65-8. Molecular formula: C23H28N2O3S. Mole weight: 412.545020 [g/mol]. Purity: 0.96. IUPACName: N-[(1S,2S)-2-amino-1,2-diphenylethyl]-7,7-dimethyl-3-oxobicyclo[2.2.1]heptane-4-sulfonamide. Canonical SMILES: CC1(C2CCC1(C(=O)C2)S(=O)(=O)NC(C3=CC=CC=C3)C(C4=CC=CC=C4)N)C. Density: 1.28g/cm³. Product ID: ACM676270658. Alfa Chemistry ISO 9001:2015 Certified.
SSTC3
SSTC3 is a casein kinase 1? (CK1?) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1242422-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120675.
SSTF
SSTF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10-Phenyl-2'-(triphenylsilyl)-10H-spiro[acridine-9,9'-fluorene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1454372-37-2. Molecular formula: C49H35NSi. Mole weight: 665.89 g/mol. Product ID: ACM1454372372. Alfa Chemistry ISO 9001:2015 Certified.
SSTR5 antagonist 2 hydrochloride
SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2988224-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114191B.
S-succinylglutathione hydrolase
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is S-succinylglutathione hydrolase. Group: Enzymes. Enzyme Commission Number: EC 3.1.2.13. CAS No. 50812-22-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3548; S-succinylglutathione hydrolase; EC 3.1.2.13; 50812-22-1. Cat No: EXWM-3548.
S-Sulfo-DL-cysteine-[2,3,3-d3]
S-Sulfo-DL-cysteine-[2,3,3-d3] is a labelled S-Sulfocysteine. S-Sulfocysteine is a potent NMDA-receptor agonist. Synonyms: White to off-white powder. Grade: 98%. CAS No. 2687960-80-9. Molecular formula: C3H4D3NO5S2. Mole weight: 204.24.
S-Sulfo-L-cysteine sodium salt
S-Sulfo-L-cysteine sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 7381-67-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S-Sulfo-L-cysteine Sodium Salt
S-Sulfo-L-cysteine sodium salt is an EAA receptor agonist. It is also reported to be an agonist at mGlu1α and mGlu5a subtypes expressed in clonal RGT cell lines. Synonyms: L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (6CI,8CI); L-Cysteine, Hydrogen Sulfate (Ester), Monosodium Salt (9CI); NSC 344479; S-Sulfocysteine Monosodium Salt; S-Sulfocysteine Sodium Salt; Sodium Cysteine-S-sulfonate. Grade: 85%. CAS No. 7381-67-1. Molecular formula: C3H6NNaO5S2. Mole weight: 223.20.
S-(-)-Sulpiride
Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-benzamide; (-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide; (-)-Sulpiride; L-Sulpiride; Levobren; Levopraid; Levosulpiride; S-(-)-Sulpiride; S-Sulpiride; l-Sulpiride; Levopride; Sulpid. Grades: Highly Purified. CAS No. 23672-07-3. Pack Sizes: 1g. US Biological Life Sciences.
ST 1059. 1-(2,5-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine (1-(2,5-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine)
A metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects. Group: Biochemicals. Alternative Names: 1-(2,5-Dimethoxyphenyl)-2-aminoethanol, de-Glymidodrine, Desglymidodrine. Grades: Highly Purified. CAS No. 3600-87-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ST 1059-d6. (Desglymidodrine-d6)
ST 1059-d6(Desglymidodrine-d6). Group: Biochemicals. Alternative Names: 1-(2,5-Dimethoxyphenyl)-2-aminoethanol-d6; α-(Aminomethyl)-2,5-dimethoxy-benzyl Alcohol-d6; α-(Aminomethyl)-2,5-dimethoxy-benzenemethanol-d6; de-Glymidodrine, Desglymidodrine-d6. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C10H9D6NO3, Molecular Weight: 203.27. US Biological Life Sciences.
Worldwide
ST 1059(desglymidodrine)
ST 1059(desglymidodrine). Group: Biochemicals. Alternative Names: 1-(2',5'-Dimethoxyphenyl)-2-aminoethanol; a-(Aminomethyl)-2,5-dimethoxy-benzyl alcohol; a-(Aminomethyl)-2,5-dimethoxy-benzenemethanol. Grades: Highly Purified. CAS No. 3600-87-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H15NO3. US Biological Life Sciences.
ST1936 is a selective, nanomolar affinity 5-HT 6 receptor agonist with K i values of 13 nM, 168 nM and 245 nM for human 5-HT 6 , 5-HT 7 and 5-HT 2B receptors, respectively. ST1936 also shows moderate affinity (K i of 300 nM) for human and rat α2 adrenergic receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1210-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103110.
ST 1936 oxalate
ST 1936 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 1210-81-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
ST271 is a potent inhibitor of protein tyrosine kinase ( PTK ), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC 50 s of 6.7 and 9 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 106392-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103097.
ST 2825
ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 interferes with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1?-mediated activation of NF-?B transcriptional activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 894787-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50937.
ST-401
ST-401, a microtubule-targeting agent (MTA), is a brain-penetrant microtubule (MT) assembly inhibitor. ST-401 disrupts microtubule (MT) function through gentle and reverisible reduction in MT assembly that triggers mitotic delay and cell death in interphase. ST-401 shows a potent antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419942-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163737.
Stabilized Gold Nanoparticles. Uses: Conjugate development, immunostaining, lateral flow assays, biological sensor development (e.g. lspr-based assays), electron microscopy, dark field microscopy, surface enhanced raman spectroscopy (sers). Group: other s.
Stabilizer 9000 (technical grade)
Stabilizer 9000 (technical grade). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4-Diisocyanato-1,3,5-tris(1-methyl)-benzene homopolymer. Product Category: Promotional Products. CAS No. 29963-44-8. Purity: Tech. Product ID: ACM29963448-1. Alfa Chemistry ISO 9001:2015 Certified.
Stachartin A
Stachartin A is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrysin; 3-Buten-2-one, 4-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H), 1'(2'H)-naphthalen]-7-yl]-, (3E)-. Grade: 98.0%. CAS No. 1978388-54-3. Molecular formula: C26H36O5. Mole weight: 428.56.
Stachartin B
Stachartin B is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone B; Spiro[benzo[2,1-b:3,4-c']difuran-2(8H),1'(2'H)-naphthalen]-8-one, 3,3',4',4'a,5',6,6',7',8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grade: 97.5%. CAS No. 1978388-55-4. Molecular formula: C23H30O5. Mole weight: 386.48.
Stachartin C
Stachartin C is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone C. Grade: 98.0%. CAS No. 1978388-56-5. Molecular formula: C29H41NO6. Mole weight: 499.64.
Stachartin D
Stachartin D is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone D. Grade: 97.0%. CAS No. 1978388-57-6. Molecular formula: C30H43NO6. Mole weight: 513.67.
Stachartin E
Stachartin E is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone E. Grade: 98.0%. CAS No. 1978388-58-7. Molecular formula: C33H41NO6. Mole weight: 547.68.
Stachybocin A
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.3 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.3 X 10-5 and 7.9 X 10-6, respectively. Synonyms: Spirodihydrobenzofuranlactam ?; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'S*)],2'a,4'aa,6'a,8'ab]]-; AM 6222A. CAS No. 158827-60-2. Molecular formula: C52H70N2O10. Mole weight: 883.12.
Stachybocin B
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.8 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.2 X 10-5 and 9.5 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'S,7'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'S*)],2'a,4'aa,6'a,7'a,8'ab]]-; AM 6222B. CAS No. 158827-61-3. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybocin C
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.9 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.5 X 10-5 and 9.4 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'S,7'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'aS*)],2'a,4'aa,6'a,7'a,8'ab]]-; AM 6222C. CAS No. 158827-62-4. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybotramide
Stachybotramide is produced by the mycelia and culture broth of Stachybotrys sp. Stachybotramide can stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). Synonyms: Spirodihydrobenzofuranlactam II; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; Stachybotrin; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, [1'R-(1'α,2'α,4'aα,6'α,8'aβ)]-. Grade: 97.5%. CAS No. 149598-71-0. Molecular formula: C25H35NO5. Mole weight: 429.55.
Stachybotrin A
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. CAS No. 144373-26-2. Molecular formula: C23H31NO5. Mole weight: 401.49.
Stachybotrin B
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. Synonyms: (+)-Stachybotrin B. CAS No. 144385-02-4. Molecular formula: C23H31NO4. Mole weight: 385.50.
Stachybotrin C
It is a neuritogenic agent produced by the strain of Stachyborrys parvispora F4708. It promotes the enlargement of the neural sinus of P12 cells, and the effect of Stachybotrin C is obvious, but the effect of Parvisporin is weak. Synonyms: Pyrano[2,3-e]isoindol-7(2H)-one, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, (2R,3R)-rel-; Pyrano[2,3-e]isoindol-7(2H)-one, 2-(4,8-dimethyl-3,7-nonadienyl)-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, [2a(E),3a]-; Antibiotic NG 245. CAS No. 150351-23-8. Molecular formula: C31H39NO5. Mole weight: 505.64.