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| Product | Description | |
|---|---|---|
| SQ 22,536 | ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| SQ 22536 - CAS 17318-31-9 | Cell-permeable adenylate cyclase inhibitor. Group: Fluorescence/luminescence spectroscopy. | |
| SQDG | SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123036-44-2. Pack Sizes: 1 mg. Product ID: HY-143692. |  |
| Squalamine | Squalamine is an aminosterol compound with potent broad spectrum antiviral activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3beta-N-1-(N-[3-(4-Aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate. Product Category: Inhibitors. Appearance: Solid. CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 628. Purity: 95%+. IUPACName: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate. Canonical SMILES: C[C@@]12[C@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CC[C@H](C(C)C)OS(=O)(O)=O)C)([H])C[C@@H](NCCCNCCCCN)CC1. Density: 1.13±0.1 g/cm³. Product ID: ACM148717902. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson , s disease mouse models [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | Squalane. Group: Biochemicals. Alternative Names: 2,6,10,15,18,23-Hexamethyltetracosane. Grades: Highly Purified. CAS No. 111-01-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C30H62. US Biological Life Sciences. |  Worldwide |
| Squalane | 100g Pack Size. Group: Building Blocks, Organics. Formula: [(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2]2. CAS No. 111-01-3. Prepack ID 13053317-100g. Molecular Weight 422.81. See USA prepack pricing. |  |
| Squalane | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardshydrocarbons & petrochemicalseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosane, perhydrosqualene,Squalane. | |
| Squalane | Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 111-01-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7113. | |
| Squalane | United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; hydrocarbons & petrochemicals; european pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosane, perhydrosqualene,Squalane. CAS No. 111-01-3. Pack Sizes: 500MG. IUPAC Name: 2,6,10,15,19,23-hexamethyltetracosane. Molecular formula: C30H62. Mole weight: 422.81. Catalog: APS111013. SMILES: CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C. Format: Neat. | |
| Squalane-d62 | Isotope labelled Squalane is used as an emollient and moisturizer in cosmetic applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 16514-83-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C30D62, Molecular Weight: 485.2. US Biological Life Sciences. | Worldwide |
| Squalane-[d62] | Squalane-[d62]. Synonyms: Squalane-d62; 2,6,10,15,19,23-Hexakis[(2H3)methyl](2H44)tetracosane. Grade: 95% atom D. CAS No. 16514-83-3. Molecular formula: C30D62. Mole weight: 485.2. |  |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| Squalene | Squalene - Product ID: NST-10-137. Category: Triterpens. Alternative Names: (E,E,E,E)-Squalene, all-trans-Squalene, Spinacen, Squalen, trans-Squalene. Purity: 98%. Test method: GC. CAS No. 111-02-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Colourless to light yellow liquid. Molecular formula: C30H50. Mole weight: 410.7. Storage: +2 +8 °C. |  |
| Squalene | Squalene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Squalene | Squalene Inhibitor. Uses: Scientific use. Product Category: T4749. CAS No. 111-02-4. |  |
| Squalene 2,3:22,23-Dioxide | Squalene 2,3:22,23-Dioxide is formed from he epoxidation of 2,3-oxidosqualene, by squalene epoxidase. Squalene 2,3:22,23-Dioxide is accumulated intracellularly during the inhibition of cholesterol biosynthesis in Chinese hamster ovary cells. Group: Biochemicals. Alternative Names: 2,3:22,23-Dioxidosqualene; Squalene 2,3:22,23-Diepoxide; (all-E)-2,3:22,23-Diepoxy-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene; 2,2'-(3,7,12,16-Tetramethyl-3,7,11,15-octadecatetraene-1,18-diyl)bis[3,3-dimethyl-oxirane]. Grades: Highly Purified. CAS No. 31063-19-1. Pack Sizes: 25mg. Molecular Formula: C30H50O2, Molecular Weight: 442.72. US Biological Life Sciences. | Worldwide |
| Squalene-d6 | Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Super Squalene-d6; trans-Squalene-d6; AddaVax-d6. CAS No. 1875101-86-2. Pack Sizes: 5 mg. Product ID: HY-N1214S. | |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. |  |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| squalene methyltransferase | Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form. Group: Enzymes. Synonyms: TMT-1; TMT-2. Enzyme Commission Number: EC 2.1.1.262. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1867; squalene methyltransferase; EC 2.1.1.262; TMT-1; TMT-2. Cat No: EXWM-1867. | |
| squalene monooxygenase | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Enzyme Commission Number: EC 1.14.14.17. CAS No. 9029-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0914; squalene monooxygenase; EC 1.14.14.17; 9029-62-3; squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Cat No: EXWM-0914. | |
| Squalene (Standard) | Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 111-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214R. | |
| squalene synthase | This microsomal enzyme catalyses the first committed step in the biosynthesis of sterols. The enzyme from yeast requires either Mg2+ or Mn2+ for activity. In the absence of NAD(P)H, presqualene diphosphate (PSPP) is accumulated. When NAD(P)H is present, presqualene diphosphate does not dissociate from the enzyme during the synthesis of squalene from farnesyl diphosphate (FPP). High concentrations of FPP inhibit the production of squalene but not of PSPP. Group: Enzymes. Synonyms: farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Enzyme Commission Number: EC 2.5.1.21. CAS No. 9077-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2758; squalene synthase; EC 2.5.1.21; 9077-14-9; farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Cat No: EXWM-2758. | |
| Squalestatin A | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grade: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73. | |
| Squalestatin B | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70. | |
| Squalestatin C | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50. | |
| Squamatic acid | Squamatic acid. Synonyms: Squamatsaure; 2-Hydroxy-4-methoxy-6-methyl-1,3-benzenedicarboxylic acid 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 2-Oxy-6-methoxy-4-methyl-isophthalsaeure-3-(3-oxy-2,5-dimethyl-4-carboxy-phenylester). CAS No. 569-36-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Squaric Acid | Crystalline, purity 99+%. Synonyms: 3,4-Dihydroxy-3-cyclobutene-1,2-dione. CAS No. 2892-51-5. Pack Sizes: 10g, 50g. Product ID: FR-0532. M.P. >300. Mole weight: 114.06. |  Frinton Laboratories |
| Squaric Acid-[d2] | Squaric Acid-[d2] is the labelled analogue of Squaric Acid. Synonyms: Squaric acid-d2; 3,4-Dihydroxy-3-cyclobutene-1,2-dione-d2. Grade: 95% by CP; 98% atom D. CAS No. 31150-56-8. Molecular formula: C4D2O4. Mole weight: 116.07. | |
| Squarunkin A | Squarunkin A is a potent and selective UNC119-cargo interaction inhibitor, interrupting the UNC119A-myristoylated Src N-terminal peptide interaction (IC50=10 nM). Squarunkin A interferes with the activation of Src kinase in cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2101958-02-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-127002. | |
| Squaw Vine Powder | Squaw Vine Powder. |  CA, FL & NJ |
| SR-0813 | SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 and EC50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC50 and EC50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (Kd=3.5 ?M) than ENL YEATS (Kd=30 nM). SR-0813 can be used for the research of acute leukemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597186-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145409. | |
| SR0987 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR1001 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR1001 | SR1001 is a selective ROR α and ROR γt inverse agonist with K i s 172 and 111 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR1078 | SR1078 is a selective agonist of retinoic acid receptor-related orphan receptor ?/? (ROR?/ROR?). SR1078 directly binds to the ligand binding domain of ROR? and ROR? and increases the transcriptional activity of these receptors, leading to stimulation of ROR?/? target gene transcription[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1246525-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14422. | |
| SR 11023 | SR 11023 is an orally active antagonist of PPAR γ, with the IC 50 value of 109 nM that plays an important role in diabetic research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820602-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160162. | |
| SR11237 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR11237 | SR11237 (BMS-649) is a potent retinoid X receptor (RXR)-selective agonist that is devoid of any RAR activity. SR11237 can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-649. CAS No. 146670-40-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107413. | |
| SR 11237 | SR 11237 is a pan retinoid X receptor (RXR) agonist. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR 11237; SR11237; SR-11237; BMS 649; BMS-649; BMS649; BMS 188649; BMS-188649; BMS188649. Product Category: Agonists. Appearance: Solid powder. CAS No. 146670-40-8. Molecular formula: C24H28O4. Mole weight: 380.48. Purity: >98%. IUPACName: 4-(2-(5,6,7,8-Tetrahydro-5,5,8,8,-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl)benzoic acid. Canonical SMILES: O=C(O)C1=CC=C(C2(C3=CC=C4C(C)(C)CCC(C)(C)C4=C3)OCCO2)C=C1. Product ID: ACM146670408-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SR 11237 | SR 11237. Group: Biochemicals. Grades: Purified. CAS No. 146670-40-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302. CAS No: 160162-42-5 |  Sarchem Laboratories New Jersey NJ |
| SR 11302 | SR 11302. Group: Biochemicals. Grades: Purified. CAS No. 160162-42-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160162-42-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15870. | |
| SR12343 | SR12343, an IKK/NF-?B inhibitor, is a NF-?B essential modulator (NEMO)-binding domain (NBD) mimetic. SR12343 inhibits TNF-?- and LPS-induced NF-?B activation by blocking the interaction between IKK? and NEMO, with an IC50 of 37.02 ?M for TNF-?-mediated NF-?B activation. SR12343 suppresses LPS-induced acute pulmonary inflammation in mice. SR12343 can be used for research of inflammatory and degenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055101-86-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123936. | |
| SR12813 | SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase , with an IC 50 value of 0.85 μM [1] [2]. SR12813 is also an efficient agonist of human pregnane X receptor ( hPXR ). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW 485801. CAS No. 126411-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100793. | |
| SR 12813 | SR 12813. Group: Biochemicals. Grades: Purified. CAS No. 126411-39-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 140333 | SR 140333. Group: Biochemicals. Grades: Purified. CAS No. 153050-21-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 141716A | SR 141716A. Group: Biochemicals. Grades: Purified. CAS No. 158681-13-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor ( NT ) antagonist with IC 50 s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| SR 142948 | SR 142948. Group: Biochemicals. Grades: Purified. CAS No. 184162-64-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| SR 142948A | SR 142948A is a non-peptide neuropeptide neuropeptin ( NT ) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-21-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124767. | |
| SR 142948A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR144528 | SR144528 is a potent and selective CB2 receptor antagonist with a Ki of 0.6 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 192703-06-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13439. | |
| SR 144528 | SR 144528. Group: Biochemicals. Alternative Names: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1, 3, 3-trimethylbicyclo[2. 2. 1]hept-2-yl)-1H-Pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. Molecular Formula: C29H34ClN3O, Molecular Weight: 476.05. US Biological Life Sciences. | Worldwide |
| SR15006 | SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5). SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. SR18662 significantly reduces growth and proliferation of colorectal cancer cells as compared with treatment with vehicle control, SR18662 showed improved efficacy in reducing the viability of multiple colorectal cancer cell lines. SR18662 treatment also reduces the expression of cyclins and components of the MAPK and WNT signaling pathways. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR15006; SR-15006; SR 15006. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2505001-54-5. Molecular formula: C16H20ClN3O4S. Mole weight: 385.86. Purity: >98%. IUPACName: (E)-3-(3-chlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide. Canonical SMILES: O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=CC(Cl)=C2. Product ID: ACM2505001545. Alfa Chemistry ISO 9001:2015 Certified. | |
| SR1555 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 16584 | SR 16584. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[(3-exo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-2H-indol-2-one. Grades: Highly Purified. CAS No. 1150153-86-8. Pack Sizes: 10mg. Molecular Formula: C17H22N2O, Molecular Weight: 270.37. US Biological Life Sciences. | Worldwide |
| SR 1664 | SR 1664. Group: Biochemicals. Grades: Purified. CAS No. 1338259-05-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 16832 | SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2088135-12-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112247. | |
| SR17018 | SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC 50 of 97 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2134602-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111454. | |
| SR-18292 | SR-18292 is a PPAR gamma coactivator-1? (PGC-1?) inhibitor, which increases PGC-1? acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095432-55-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101491. | |
| SR1848 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR18662 | SR18662 is an optimized anticancel agent based on ML264. SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. SR18662 showed improved efficacy in reducing the viability of multiple colorectal cancer cell lines. Flow cytometry analysis following SR18662 treatment showed an increase in cells captured in either S or G2-M phases of the cell cycle and a significant increase in the number of apoptotic cells, the latter a unique property compared with ML264 or SR15006. SR18662 treatment also reduces the expression of cyclins and components of the MAPK and WNT signaling pathways. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR18662; SR-18662; SR 18662. Product Category: Others. Appearance: Solid powder. CAS No. 2505001-62-5. Molecular formula: C16H19Cl2N3O4S. Mole weight: 420.31. Purity: >98%. IUPACName: (E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide. Canonical SMILES: O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=C(Cl)C(Cl)=C2. Product ID: ACM2505001625. Alfa Chemistry ISO 9001:2015 Certified. | |
| SR18662 | SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2505001-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136530. | |
| SR 202 | SR 202. Group: Biochemicals. Grades: Purified. CAS No. 76541-72-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-202 | ?98% (HPLC), crystalline. Group: Fluorescence/luminescence spectroscopy. | |
| SR2211 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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