A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection. Staphylokinase recombinant produced in e. coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 15.5 kd.the staphylokinase is purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK. Purity: Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. SAK. Mole weight: 15.5 kDa. Activity: 4600 IU/mg. Stability: Lyophilized SAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SAK should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered White lyophilized (freeze-dried) powder. Source: E. coli. Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK. Cat No: NATE-0915.
Staplabin
Staplabin is a substance produced by the fungus Stachybotrys microspora IFO 30018. Staplabin has the effect of stimulating the binding of plasminogen to fibrin and U937 cells. CAS No. 183006-79-3. Molecular formula: C28H39NO6. Mole weight: 485.61.
Stapokibart
Stapokibart (CM310) is a humanised monoclonal antibody targeting IL-4Rα and efficiently blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4R&alpha. Stapokibart has the capacity to interact with IL-4Rα in humans, cynomolgus monkeys, and rats [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CM310. CAS No. 2734715-10-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990093.
Star Anise Oil
Star Anise (or Anise) essential oil, has a fresh, sweet, and spicy, liquorice-like aroma. It is used for its carminative, digestive, stimulant and diuretic properties. Star Anise oil is obtained from steam distillation from fresh and partly dried fruits and it is present in the fruit wall, not in the seed. Star Anise Oil can be useful in diffuser and inhaler blends intended to help ease bronchitis, colds and the flu. Uses: Flavor and Fragrances. Group: Plant Extracts. INCI Names: Illicium Verum Seed Oil. Grades: FOOD GRADE. CAS No. 68952-43-2 ; 84650-59-9. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: SA-001. Olfactive Profile: Sweet, spicy, reminiscent of anethole. EC No: 283-518-1. FEMA No: 2096. Origin: Spain.
New Jersey
Star Anise Oil
Star Anise Oil. Synonyms: Anise Oil. CAS No. 8007-70-3. Product ID: PE-0412. Category: Flavoring agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Star Anise Oil; Corrective Agents; Flavoring agent; 8007-70-3; 8007-70-3. UNII: 6Y89129C8H. Grade: Pharmceutical Excipients. Administration route: Dental use; Oral administration. Dosage Form: Elixir, toothpaste, tooth powder, drops. Stability and Storage Conditions: Store this product in a cool and dry place in an airtight container away from light. Do not contact with oxidizing agent, acid, alkali. Source and Preparation: This product is a volatile oil obtained by steam distillation from fresh branches and leaves or mature fruits of anise, a plant of the orchidaceae. The oil yield of fresh fruit is 2%-3%, that of dry fruit is 8%-12%, and that of branches and leaves is 0.3%-0.5%. Applications: This product is used as natural flavor for food and medicinal excipients. Used elixir, toothpaste, tooth powder, drops, aromatic heavy agent, etc. Safety: This product is a natural aromatic oil, non-toxic, non-irritating to skin and mucous membranes, and generally recognized as safe.
Starburst(pamam)dendrimer,generation 10,5 wt. % solution in methyl alcohol
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-84-9. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-25-8. Pack Sizes: 25 kg. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch, 1% Aqueous, Laboratory Grade, 1 L
Formula: (C6H10O5)n. Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. CAS No. 9005-25-8. Product ID: 892510. -- SOLD FOR EDUCATIONAL USE ONLY --
Formula: (C6H10O5)n. Characteristic: White powder. Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. CAS No. 9005-25-8. Product ID: 892502. -- SOLD FOR EDUCATIONAL USE ONLY --
Starch, Corn, Powder, Reagent Grade, 500 g
Formula: (C6H10O5)n. Characteristic: White powder. Storage Code: Green; general chemical storage. Grades: chem-grade reagent. CAS No. 9005-25-8. Product ID: 892501. -- SOLD FOR EDUCATIONAL USE ONLY --
for use with Total Dietary Fiber Control Kit, TDF-C10. Group: Reagents for food analysis.
Starch from corn
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-25-8. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch (from potato)
Starch from potato is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Edible corn starch (from potato). CAS No. 9005-25-8. Pack Sizes: 100 g. Product ID: HY-B2225A.
Starch from potato
for electrophoresis. Group: Fluorescence/luminescence spectroscopy.
Starch from potato
500g Pack Size. Group: Biochemicals, Carbohydrates, Diagnostic Raw Materials, Sugars. CAS No. 9005-25-8. Prepack ID 90018757-500g. See USA prepack pricing.
Starch from potato
Powder. Group: Polysaccharide.
Starch From Potato
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-25-8. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: (C6H10O5)n. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch from rice
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-25-8. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch from wheat
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-25-8. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch IP/BP/USP
Starch IP/BP/USP.
Starch, oxidized (technical grade)
Starch, oxidized (technical grade). Uses: Designed for use in research and industrial production. Product Category: Promotional Products. CAS No. 65996-62-5. Purity: Tech. Product ID: ACM65996625-2. Alfa Chemistry ISO 9001:2015 Certified.
Starch (Smithies)
100g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: (C6H10O5)n. CAS No. 9005-84-9. Prepack ID 43539915-100g. Molecular Weight 342.3. See USA prepack pricing.
Starch soluble
Starch soluble is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9005-84-9. Pack Sizes: 5 g. Product ID: HY-W094695.
Starch, soluble
Starch is a fine, white, odorless powder. Note that granules from different vegetable sources vary in shape, size, and general appearance. A mixture of the carbohydrate polymers amylose amylopectin varying according to the vegetable source. Principally used for food.;DryPowder; DryPowder, WetSolid;WetSolid;Solid;WHITE POWDER.;Fine, white, odorless powder.;Fine, white, odorless powder. [Note: A carbohydrate polymer composed of 25% amylose & 75% amylpectin.]. Group: Polysaccharide. CAS No. 9005-84-9. Product ID: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol. Molecular formula: 342.3g/mol. Mole weight: C12H22O11;C12H22O11. C (C1C (C (C (C (O1)OC2C (OC (C (C2O)O)O)CO)O)O)O)O. InChI=1S/C12H22O11/c13-1-3-5 (15)6 (16)9 (19)12 (22-3)23-10-4 (2-14)21-11 (20)8 (18)7 (10)17/h3-20H, 1-2H2/t3-, 4-, 5-, 6+, 7-, 8-, 9-, 10-, 11+, 12-/m1/s1. GUBGYTABKSRVRQ-ASMJPISFSA-N.
Starch, soluble
Starch, soluble. Synonyms: Soluble Starch; Starch, Soluble, Purified. CAS No. 9005-84-9. Product ID: PE-0615. Category: Thickening Agents; Stabilizer; Filler; Sugar-free drug Excipients. Product Keywords: Other Materials; Stabilizers; PE-0615; Starch, soluble; Thickening Agents; Stabilizer; Filler; Sugar-free drug Excipients; ; 9005-84-9. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Store in a sealed container. Source and Preparation: Soluble starch uses starch as raw material and can be prepared by semi-dry method combined with acid enzyme. Or use high-pressure spray gelatinization and then spray drying, heat treatment in alcohol solution, alcohol alkaline solution treatment, and polyol treatment to prepare cold water-soluble starch.
Starch, soluble
1kg Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: (C6H10O5)n. CAS No. 9005-84-9. Prepack ID 37742653-1kg. See USA prepack pricing.
Starch Soluble
Starch Soluble. CAS No. 9005-84-9. Molecular Formula (C6H10O5)n. Chemical Reagents
Cater Chemicals Corp. Illinois IL
Starch, Soluble Potato, ACS Grade, 100 g
Formula: (C6H10O5)n. Characteristic: White powder. Storage Code: Green; general chemical storage. Grades: chem-grade acs. CAS No. 9005-84-9. Product ID: 892529. -- SOLD FOR EDUCATIONAL USE ONLY --
Starch, Soluble Potato, Reagent Grade, 500 g
Formula: (C6H10O5)n. Characteristic: White powder. Storage Code: Green; general chemical storage. Grades: chem-grade reagent. CAS No. 9005-84-9. Product ID: 892532. -- SOLD FOR EDUCATIONAL USE ONLY --
starch synthase (glycosyl-transferring)
The accepted name varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase. Similar to EC 2.4.1.11 [glycogen(starch) synthase] but the preferred or mandatory nucleoside diphosphate sugar substrate is ADP-α-D-glucose. The entry covers starch and glycogen synthases utilizing ADP-α-D-glucose. Group: Enzymes. Synonyms: ADP-glucose-starch glucosyltransferase; adenosine diphosphate glucose-starch glucosyltransferase; adenosine diphosphoglucose-starch glucosyltransferase; ADP-glucose starch synthase; ADP-glucose synthase; ADP-glucose transglucosyla. Enzyme Commission Number: EC 2.4.1.21. CAS No. 9030-10-8, 37338-93-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2437; starch synthase (glycosyl-transferring); EC 2.4.1.21; 9030-10-8, 37338-93-5; ADP-glucose-starch glucosyltransferase; adenosine diphosphate glucose-starch glucosyltransferase; adenosine diphosphoglucose-starch glucosyltransferase; ADP-glucose starch synthase; ADP-glucose synthase; ADP-glucose transglucosylase; ADP-glucose-starch glucosyltransferase; ADPG starch synthetase; ADPG-starch glucosyltransferase; starch synthetase; ADP-glucose:1,4-α-D-glucan 4-α-D-glucosyltransferase. Cat No: EXWM-2437.
starch synthase (maltosyl-transferring)
The enzyme from the bacterium Mycobacterium smegmatis is specific for maltose. It has no activity with α-D-glucose. Group: Enzymes. Synonyms: α1,4-glucan:maltose-1-P maltosyltransferase; GMPMT. Enzyme Commission Number: EC 2.4.99.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2700; starch synthase (maltosyl-transferring); EC 2.4.99.16; α1,4-glucan:maltose-1-P maltosyltransferase; GMPMT. Cat No: EXWM-2700.
Stargel Type A
Stargel Type A. Sodium Starch Glycolate is the internally cross-linked sodium salt of carboxymethyl starch. It is a off-white, odorless, tasteless, and relatively free-flowing powder typically used in pharmaceutical applications. Dosage Form: Capsule, Orally Disintegrating Tablet, Tablet. Functionality: Cellulose Filling, Disintegrant, Dissolution Accelerator, Rapid Release Agent. Process: Direct Compression, Dry Granulation, Wet Granulation.
Sigachi US Inc
Star San Sanitizer for beer brewing
Star San is a high foaming acid based sanitizer. It is used to sterilize brewing equipment and supplies with a contact of one minute. Star San is odorless, tasteless, and safe. Since it is high foaming, it ensures plenty of coverage and contact time in larger vessels, making sure to get into all of the nooks and cranies. Any foam leftover in your container will not effect your beer, wine, or mead. Uses: Sanitizer. CAS No. 7664-38-2, 85536-14-7. Pack Sizes: 4 oz, 8 oz, 16 oz, 32 oz Bottles.
recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
STAT2 human
recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
STAT3 Control Cell Extracts (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF)
Stat3 is a key signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development. Additionally, Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by tyrosine phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by serine phosphorylation at Ser727, apparently via the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function: the relative expression levels of Stat3alpha (86kD) and Stat3beta (79kD) depend on cell type, ligand exposure or maturation stage of the cells. It is notable that Stat3beta lacks the serine phosphorylation site within the C-terminal transcriptional activation domain. Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences.
Worldwide
STAT3-IN-13
STAT3-IN-13 (compound 6f) is a potent STAT3 inhibitor. STAT3-IN-13 has anti-proliferative effects and binds to the STAT3 SH2 domain with a KD of 0.46 ?M. STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705 and downstream target gene expression. STAT3-IN-13 induces apoptosis in vitro and suppresses the growth and metastasis of tumor in vivo. STAT3-IN-13 can be used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2248552-86-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150603.
STAT3-IN-14
STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3 [1]. Uses: Scientific research. Group: Natural products. CAS No. 123297-90-5. Pack Sizes: 1 mg. Product ID: HY-N10472.
STAT3-IN-17
STAT3-IN-17 is a moderate STAT3 inhibitor ( IC 50 =0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase ( PFOR ), and inhibits Helicobacter pylori [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245814-52-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148706.
STAT3-IN-25
STAT3-IN-25 (compound 2p) is a potent STAT3 inhibitor with a p-trifluoroethoxy benzyl substituent. STAT3-IN-25 shows STAT3 luciferase inhibition activity using HEK293T cells with an IC 50 of 22.3 nM and ATP production inhibition activity using BxPC-3 cells with an IC 50 of 32.5 nM. STAT3-IN-25 shows potent antiproliferation activities on BxPC-3 and Capan-2 cells. STAT3-IN-25 has the potential for pancreatic cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2591440-75-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160496.
A cell-permeable binaphthol-sulfonamide compound that competitively disrupts Stat3 SH2 domain-pY peptide interaction and acts as a reversible inhibitor of Stat3 activation and Stat3-dependent gene transcription. Shown to block G-CSF stimulated pStat3 (IC50=4.1, 4.5 and 8.3uM in KG-1, Kasumi-1 and NB-4 cells, respectively), with no effect on ligand-induced pStat1 and selectively induce apoptosis of Stat3-dependent AML cells ((EC50 of 6-8uM) and growth arrest. Moderately affects Tie2 kinase activity (<50%) with minimal effect on JAK1, JAK2, Src family kinases and pERK1/2 and pAKT at 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A cell-permeable oxadiazolyl-quinolinecarboxamide that is shown to selectively suppress STAT3, but not STAT1, STAT5a, or STAT5b, DNA binding activity and prevent IL-6-stimulated STAT3 dimerization in HEK293 cells (by 99% at 100uM), as well as inhibit the expression of STAT3 target genes both in cultures in vitro (effective conc. 50uM) and in SCC3-derived tumors in mice in vivo (160mg/kg/day; p.o.). Group: Biochemicals. Grades: Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
STAT3 Inhibitor XVI (IL-6 Inhibitor)
A cell-permeable, arylsulphonamidyl thiophene amide that is shown to reduce IL-6-induced STAT3 transcriptional activity (EC50=15uM) in a luciferase reporter assay, in HeLa cells. It selectively inhibits STAT3, but not STAT1, phosphorylation following IL-6 stimulation in both HeLa and MDA-MB-231 breast cancer cells at concentrations of 10-30uM and 30-100uM, respectively. Following IL-6 stimulation, it suppresses the cell viability of STAT3-dependent cancer cells by 40% compared with that of STAT3-null cancer cells at the low micromolar level. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
STAT4 human
recombinant, expressed in insect cells, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
STAT6-IN-1 (Compound 19a) is a STAT6 inhibitor with a high affinity for the SH2 domain of STAT6 (IC50=0.028 μM). STAT6-IN-1 can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1637532-68-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148096.
STAT6-IN-2
STAT6-IN-2 (Compound R-84) is a STAT6 inhibitor that can inhibit the tyrosine phosphorylation of STAT6. STAT6-IN-2 can also inhibit the secretion of eotaxin-3. STAT6-IN-2 can be used in the research of immune diseases and allergic inflammatory diseases such as asthma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1355594-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153991.
STAT6-IN-3
STAT6-IN-3 is a phosphopeptide mimic targeting the SH2 domain of STAT6 and has a high affinity for STAT6 (IC50: 0.04 ?M). STAT6-IN-3 can be used in the research of inflammation such as asthma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371919-80-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153992.
STAT6-IN-4
STAT6-IN-4 (Ex. 78) is a STAT6 inhibitor, with an IC50 of 0.34 ?M. STAT6-IN-4 can be used in the research of diseases such as inflammatory and allergic diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033742-14-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-158398.
STAT6-IN-5
STAT6-IN-5 (compound 84) is a STAT6 inhibitor (IC50=0.24 ?M), which can be used for the research of inflammatory diseases and allergic diseases (e.g. atopic dermatitis)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033742-22-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-158399.
Stathmin, His tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
Statine
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3S,4S)-Statine; (S,S)-Statine. CAS No. 49642-07-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101877.