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| Product | Description | |
|---|---|---|
| CDC7/DBF4 active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Cdc7-IN-1 | Cdc7-IN-1 is a highly potent, selective and ATP competitive Cdc7 kinase inhibitor, with an IC50 of 0.6 nM at 1 mM ATP and a slow deceleration characteristic. It can effectively inhibit the activity of Cdc7 in cancer cells and induce cell death. Synonyms: Ethyl (5Z)-2-[(2-chlorophenyl)amino]-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 2-[(2-chlorophenyl)amino]-4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, ethyl ester, (5Z)-. Grade: ≥99%. CAS No. 1402055-25-7. Molecular formula: C21H16ClN3O4. Mole weight: 409.82. |  |
| Cdc7-IN-3 | Cdc7-IN-3, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-B). Synonyms: Isopropyl (5Z)-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, 1-methylethyl ester, (5Z)-. Grade: ≥95%. CAS No. 1402057-87-7. Molecular formula: C20H22N4O5. Mole weight: 398.41. | |
| Cdc7-IN-4 | Cdc7-IN-4, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-C). Synonyms: Isopropyl (5Z)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-{[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino}-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-[[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino]-, 1-methylethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402059-21-5. Molecular formula: C22H24F3N5O4. Mole weight: 479.45. | |
| Cdc7-IN-5 | Cdc7-IN-5, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-B). Synonyms: Ethyl (5Z)-2-(7-methoxy-3,4-dihydro-2(1H)-isoquinolinyl)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 2-(3,4-dihydro-7-methoxy-2(1H)-isoquinolinyl)-4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, ethyl ester, (5Z)-. Grade: ≥95%. CAS No. 1402057-86-6. Molecular formula: C25H23N3O5. Mole weight: 445.47. | |
| Cdc7-IN-6 | Cdc7-IN-6 is a potent Cdc7 kinase inhibitor (IC50 = 4 nM) with antitumor activity. (Extracted from patent WO2019165473A1, compound I-D). Synonyms: AS-0141; Ethyl (5Z)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-{[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino}-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-[[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino]-, ethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402057-88-8. Molecular formula: C21H22F3N5O4. Mole weight: 465.43. | |
| Cdc7-IN-7 | Cdc7-IN-7, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-E). Synonyms: Cyclopropylmethyl (5Z)-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, cyclopropylmethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402059-17-9. Molecular formula: C21H22N4O5. Mole weight: 410.42. | |
| CDC801 | A potent, orally active and dual inhibitor of phosphodiesterase 4 (PDE4) (IC50= 1.1 μM) and tumor necrosis factor-α (TNF-α) (IC50= 2.5 μM). Synonyms: CDC801; CDC 801; CDC-801; 3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide. CAS No. 192819-27-5. Molecular formula: C23H24N2O5. Mole weight: 408.45. | |
| CDCFDA | CDCFDA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(and-6)-Carboxy-2',7'-dichlorofluoresceindiacetate. Product Category: Fluorescein Fluorophores. CAS No. 127770-45-0. Molecular formula: C25H14Cl2O9. Mole weight: 529.28. Purity: 95%+. Product ID: ACM127770450-2. Alfa Chemistry ISO 9001:2015 Certified. Categories: 144489-09-8, CD CF Salmantino. |  |
| CDCFDA, SE | CDCFDA, SE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate, succinimidyl ester. Product Category: Fluorescein Fluorophores. Molecular formula: C29H17Cl2NO11. Mole weight: 626.35. Product ID: ACMA00013920. Alfa Chemistry ISO 9001:2015 Certified. | |
| CDD0102 | CDD0102 is a selective M1 agonist which stimulated the secretion of APP from CHO-K1 cells expressing M1 receptors and penetrated into the brain following i.p. administration in rodents. Synonyms: CDD0102; CDD 0102; CDD-0102; 3-ethyl-5-(1,4,5,6-tetrahydropyrimidin-5-yl)-1,2,4-oxadiazole; 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine; CDD-0102A. CAS No. 146422-58-4. Molecular formula: C8H12N4O. Mole weight: 180.21. | |
| CDD-1653 | CDD-1653 is a potent and selective BMPR2 inhibitor (IC50=2.8 nM). CDD-1653 reduces the ability of ATP to bind to the kinase domain of BMPR2, thereby affecting the phosphorylation of SMAD1/5/8 transcription factors, which play a key role in the BMP signaling pathway. CDD-1653 can be used to study diseases related to the BMP signaling pathway[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034216-44-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164145. |  |
| CDD3505 | CDD3505 is an inducer of hepatic cytochrome P450IIIA (CYP3A) activity that elevates high density lipoprotein cholesterol (HDL). Uses: Cytochrome p-450 enzyme inhibitors. Synonyms: 4-Nitro-1-trityl-1H-imidazole; 1-Trityl-4-nitroimidazole. CAS No. 173865-33-3. Molecular formula: C22H17N3O2. Mole weight: 355.39. | |
| CDDD3602 | Tematropium, a neurological agent, is a soft anticholinergic drug. Synonyms: Tematropium; HGP6; Tematropium methylsulfate; Tematropium metilsulfate; 3alpha-Hydroxy-8-methyl-1alphaH,5alphaH-tropanium methyl sulfate (salt), (±)-ethyl hydrogen phenylmalonate; 8-Azoniabicyclo(3.2.1)octane, 3-(3-ethoxy-1,3-dioxo-2-phenylpropoxy)-8,8-dimethyl-, endo-(±)-, methyl sulfate; (3-endo)-3-[(3-Ethoxy-3-oxo-2-phenylpropanoyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane methyl sulfate. Grade: ≥95%. CAS No. 113932-41-5. Molecular formula: C21H31NO8S. Mole weight: 457.54. | |
| CDDO-2-P-Im | CDDO-2-P-Im is an orally active inhibitor of necroptosis. Synonyms: CDDO-2P-Im. Grade: 98%. CAS No. 1883650-96-1. Molecular formula: C39H46N4O3. Mole weight: 618.8. | |
| CDDO-3-P-Im | CDDO-3-P-Im is an orally active inhibitor of necroptosis. Synonyms: CDDO-3P-Im. Grade: 98%. CAS No. 1883650-95-0. Molecular formula: C39H46N4O3. Mole weight: 618.8. | |
| CDDO-DhTFEA | CDDO-DhTFEA can effectively activate Nrf2 and inhibit the pro-inflammatory transcription factor NF-κB. Synonyms: RTA Dh404; RTA Dh404RTA Dh404. CAS No. 1191265-33-4. Molecular formula: C33H45F3N2O3. Mole weight: 574.7. | |
| CDDO-EA | CDDO-EA is an activator of Nrf2/ARE. It has neuroprotective effect. Synonyms: CDDO ethyl amide; RTA405; TP319; RTA 405; TP 319; RTA-405; TP-319. Grade: >98%. CAS No. 932730-51-3. Molecular formula: C33H46N2O3. Mole weight: 518.73. | |
| CDDO Im | CDDO Im. Group: Biochemicals. Grades: Purified. CAS No. 443104-02-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| CDDO-Im | CDDO-Im (RTA-403) is an activator of Nrf2 and PPAR , with K i s of 232 and 344 nM for PPARα and PPARγ [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA-403; TP-235; CDDO-Imidazolide. CAS No. 443104-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15725. | |
| CDDO Imidazolide | CDDO Imidozolide is a synthetic triterpenoid as a Nrf2 signaling activator with highly active in suppressing cellular proliferation of human leukemia and breast cancer cell. Uses: Nrf2 signaling activator. Synonyms: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile. Grade: ≥98 %. CAS No. 443104-02-7. Molecular formula: C34H43N3O3. Mole weight: 541.72. | |
| CDDO Imidazolide | CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers. Group: Biochemicals. Alternative Names: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; CDDO-Im; RTA 403; TP 235. Grades: Highly Purified. CAS No. 443104-02-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| CDDO-Me (NSC 713200, Bardoxolone Methyl, BARD, Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate) | A cell-permeable, bioavailable synthetic oleanane triterpenoid compound with anti-inflammatory, anti-tumor and cytoprotective properties. Shown to significantly reduce the expression of several inflammatory mediators, including IL-6, IL-10, IL-12, TNFalpha, Mip1alpha and others. Reverses high fat diet-induced type 2 diabetes in C57BL/6 mice (3mg/kg) and improves glucose homeostasis and insulin sensitivity. Down-regulates lipogenic gene expression in hepatocytes. Exhibits anti-proliferative activity in osteosarcoma cells (IC50 = 800, 150, 330, and 170nM in HOB-c, KHOS, KHOSR2, and U2OS cells, respectively). Enhances the effectiveness of chemotherapeutic agents by inducing intrinsic mitochondrial-dependent apoptotic pathway. Reported to interact with multi cellular targets, namely, Nrf2-Keap1, IKK, JAK-STAT, PPARg, ErbB2, PTEN, mTOR and Arp3 and covalently modify active site Cys residue via Michael addition. Group: Biochemicals. Grades: Highly Purified. CAS No. 218600-53-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CDDO Methyl Ester | CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer. Group: Biochemicals. Alternative Names: 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402. Grades: Highly Purified. CAS No. 218600-53-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CDDO-TFEA | CDDO-TFEA is an Nrf2/ARE pathway activator. CDDO-TFEA inhibits BACH1 via reducing BACH1 nuclear levels while accumulating its cytoplasmic form. Synonyms: 2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-oleana-1,9(11)-dien-28-amide; CDDO-trifluoroethyl-amide. CAS No. 932730-52-4. Molecular formula: C33H43F3N2O3. Mole weight: 572.7. | |
| CDDU-Me | CDDU-Me is an activator of the Nrf2 pathway, which induces the expression of cytoprotective genes regulated by Nrf-2 in vivo. It has anti-inflammatory, anti-tumor and cell protection properties. Synonyms: AC-31539. CAS No. 1616932-17-2. Molecular formula: C32H43NO4. Mole weight: 505.7. | |
| C-Demethyl clethodim | C-Demethyl clethodim. Group: Biochemicals. Alternative Names: (E) -2-[1-[[ (3-Chloro-2-propenyl) oxy]imino]ethyl]-5-[2- (ethylthio) propyl]-1, 3-cyclohexanedione. Grades: Highly Purified. CAS No. 112301-96-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H24ClNO3S. US Biological Life Sciences. | Worldwide |
| C-Desmethyl Metoprolol | A new byproduct detected in Metoprolol tartrate. Group: Biochemicals. Alternative Names: 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol; H 173/09. Grades: Highly Purified. CAS No. 109632-08-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| C-Desmethyl Metoprolol | C-Desmethyl Metoprolol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Metoprolol USP Related Compound A, (2RS)-1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol, Metoprolol Tartrate Imp. A (EP),Metoprolol Succinate Imp. A (EP), Metoprolol Imp. A (EP), Metoprolol USP RC A. CAS No. 109632-08-8. IUPAC Name: 1-(ethylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol. Molecular formula: C14H23NO3. Mole weight: 253.34. Catalog: APS109632088. SMILES: CCNCC(O)COc1ccc(CCOC)cc1. Format: Neat. | |
| CDFI | CDFI is an inhibitor of the lipid II flippase MurJ. CDFI potentiates the activity of β-lactams against MRSA [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1199797-92-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156009. | |
| CDH13 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CDH18 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CDi(1-adamantyl)-n-butylphosphine | CDi(1-adamantyl)-n-butylphosphine. Group: Biochemicals. Alternative Names: Cataxium A. Grades: Highly Purified. CAS No. 321921-71-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C24H39P. US Biological Life Sciences. | Worldwide |
| c-di-2'-d-2''-O-Me-AMP | c-di-2'-d-2''-O-Me-AMP is an analogue of c-diAMP, the bacterial second messenger. Synonyms: 2'- Deoxy- 2''- O- methyl- cyclic diadenosine monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C21H26N10O11P2 (free acid). Mole weight: 656.5 (free acid). | |
| c-di-2'-dAMP | c-di-2'-dAMP is an analogue of c-diAMP, the bacterial second messenger. Synonyms: 2'- Deoxy- cyclic diadenosine monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H24N10O11P2 (free acid). Mole weight: 642.4 (free acid). | |
| c-di-2'-dGMP | c-di-2'-dGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions. Synonyms: 2'- Deoxy- cyclic diguanosine monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 132182-18-4. Molecular formula: C20H24N10O13P2 (free acid). Mole weight: 674.4 (free acid). | |
| c-di-AMP | c-di-AMP is an agonist of stimulator of interferon genes (STING) for treating cancer. It is a second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance, and other functions. Synonyms: Cyclic diadenylate monophosphate; Cyclic diadenylate; Adenylic acid, cyclic ester; 3',5'-Cyclic diadenylic acid; Cyclic di-3',5'-adenylate; Cyclic di-AMP; Cyclic-di-AMP; Cyclic diadenosine monophosphate; (2R,3R,3aS,7aR,9R,10R,10aS,14aR)-2,9-bis(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxyoctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecine 5,12-dioxide. Grade: ≥95%. CAS No. 54447-84-6. Molecular formula: C20H24N10O12P2. Mole weight: 658.41. | |
| c-di-AMP diammonium | c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. Synonyms: Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium; 3'-Adenylic acid, adenylyl-(3'→5')-, cyclic nucleotide, diammonium; Adenylic acid, cyclic ester diammonium; 3',5'-Cyclic diadenylic acid diammonium; Cyclic di-3',5'-adenylate diammonium; Cyclic diadenylate monophosphate diammonium; (2R,3R,3aS,7aR,9R,10R,10aS,14aR)-2,9-bis(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxyoctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecine 5,12-dioxide diammonium. Grade: ≥95%. Molecular formula: C20H30N12O12P2. Mole weight: 692.47. | |
| c-di-AMP disodium | c-Di-AMP sodium salt is an endogenous STING and DDX41 agonist; mediates DDX41-STING interaction. It activates STING-dependent IFN-β production in mouse and human cells. Synonyms: 3',5'-Cyclic diadenylic acid sodium salt; Cyclic diadenylate disodium; Cyclic-di-AMP disodium; 3'-Adenylic acid, adenylyl-(3'→5')-, cyclic nucleotide, disodium; Adenylic acid, cyclic ester disodium; 3',5'-Cyclic diadenylic acid disodium; Cyclic di-3',5'-adenylate disodium; Cyclic diadenylate monophosphate disodium. CAS No. 2734909-87-4. Molecular formula: C20H22N10Na2O12P2. Mole weight: 702.38. | |
| c-di-AMP disodium | c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses[1][2][3][4]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclic diadenylate disodium; Cyclic-di-AMP disodium. CAS No. 2734909-87-4. Pack Sizes: 10 mM * 1 mL; 500 ?g; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12326A. | |
| c-di-AMP sodium | c-di-AMP sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. Synonyms: Cyclic diadenylate sodium; Cyclic-di-AMP sodium; 3'-Adenylic acid, adenylyl-(3'→5')-, cyclic nucleotide, sodium; Adenylic acid, cyclic ester sodium; 3',5'-Cyclic diadenylic acid sodium; Cyclic di-3',5'-adenylate sodium; Cyclic diadenylate monophosphate sodium. Grade: ≥95%. Molecular formula: C20H24N10O12P2.xNa. Mole weight: 658.41 (free acid). | |
| CDIBA | CDIBA is a potent and selective cytosolic phospholipase A2 (cPLA2) inhibitor. Synonyms: 4-[2-(1-benzhydryl-5-chloro-2-methylindol-3-yl)ethoxy]benzoic acid. Grade: 99%. CAS No. 479422-22-5. Molecular formula: C31H26ClNO3. Mole weight: 496. | |
| c-Di-GMP | c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP; cGpGp; Cyclic diguanylic acid; cdiGMP; 3',5'-Cyclic diguanylic acid; c-(Gpgp); Bis(3',5')-cyclic diguanylic acid. Grade: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41. | |
| c-di-GMP Fluorinated | A STING agonist. CAS No. 1334145-18-4. Molecular formula: C20H20F2N10O12P2.2Na. Mole weight: 738.36. | |
| c-di-IMP | c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination. Synonyms: Cyclic diinosine monophosphate; 3'-Inosinic acid, inosinylyl-(3'→5')-, cyclic nucleotide; Cyclic-di-IMP; 3',3'-Cdimp; 9,9'-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecine-2,9-diyl)bis(1,9-dihydro-6H-purin-6-one). Grade: ≥95% by HPLC. CAS No. 79940-41-3. Molecular formula: C20H22N8O14P2. Mole weight: 660.38. | |
| C-DIM12 | C-DIM12 is a novel synthetic activator of Nurr1. C-DIM12 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Synonyms: C-DIM 12; C-DIM-12. Grade: 98%. CAS No. 178946-89-9. Molecular formula: C23H17ClN2. Mole weight: 356.85. | |
| C-DIM12 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| C-DIM12 | C-DIM12 is a potent, orally active Nurr1 antagonist. C-DIM12 inhibits the tumor growth and autophagy, and induces the cell apoptosis. C-DIM12 has anti-inflammatory and neuroprotective effects, and can be used for cancer and neurological disease study[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DIM-C-pPhCl. CAS No. 178946-89-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19808. | |
| c-di-UMP | A STING agonist negative control. Synonyms: Cyclic di-uridine monophosphate, c-di-UMP sodium salt. CAS No. 73120-97-5. Molecular formula: C18H20N4O16P2.2Na. Mole weight: 656.3. | |
| CDK12-IN-2 | CDK12-IN-2, a potent and selective nanomolar CDK12 inhibitor (IC50 = 52 nM) with good physicochemical properties, inhibits phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II, and can be used as an excellent chemical probe for the study of CDK12 function. It is also a strong CDK13 inhibitor because CDK13 is the closest homologue of CDK12. It shows excellent kinase selectivity for CDK12 over CDK2, 9, 8, and 7. Synonyms: Urea, N-[trans-4-[(5-cyano-2-pyridinyl)amino]cyclohexyl]-N-[4-(1,6-dihydro-1-methyl-6-oxo-3-pyridinyl)phenyl]-N'-(phenylmethyl)-; 3-Benzyl-1-(trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)urea. CAS No. 2244987-03-7. Molecular formula: C32H32N6O2. Mole weight: 532.64. | |
| CDK12-IN-4 | CDK12-IN-4 is a pyrazolotriazine that is a potent inhibitor of CDK12 with an IC50 of 0.641 μM at high ATP (2 mM). At high ATP (2 mM), it has no effect on CDK2/Cyclin E (IC50>20 μM) and CDK9/Cyclin T1 (IC50>20 μM). (WO2021116178A1). Synonyms: Pyrazolo[1,5-a]-1,3,5-triazin-4-amine, 8-cyclopropyl-N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-2-(4-morpholinyl)-. CAS No. 2651196-69-7. Molecular formula: C20H20F2N8O. Mole weight: 426.42. | |
| CDK12-IN-5 | CDK12-IN-5 is a pyrazolotriazine that is a potent inhibitor of CDK12 with an IC50 of 23.9 nM at high ATP (2 mM). At high ATP (2 mM), it has no effect on CDK2/Cyclin E (IC50 = 173 μM) and CDK9/Cyclin T1 (IC50 = 127 μM). (WO2021116178A1). Synonyms: Pyrazolo[1,5-a]-1,3,5-triazin-4-amine, N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-2-(4-morpholinyl)-8-(trifluoromethyl)-. CAS No. 2651200-35-8. Molecular formula: C18H15F5N8O. Mole weight: 454.36. | |
| CDK12-IN-6 | CDK12-IN-6 is a pyrazolotriazine that is a potent inhibitor of CDK12 with an IC50 of 1.19 μM at high ATP (2 mM). At high ATP (2 mM), it has no effect on CDK2/Cyclin E (IC50>20 μM) and CDK9/Cyclin T1 (IC50>20 μM). (WO2021116178A1). Synonyms: 8-cyclopropyl-N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-2-(piperazin-1-yl)pyrazolo[1,5-a][1,3,5]triazin-4-amine. CAS No. 2651196-71-1. Molecular formula: C20H21F2N9. Mole weight: 425.44. | |
| Cdk1/2 Inhibitor III | Cdk1/2 Inhibitor III is a selective inhibitor of Cdk1/2 with an IC50 of 2.1 μM for CDK1/cyclin B. It is a cell-permeable triazolo-diamine compound with anti-proliferative properties in various human cancer cells (IC50 = 20 nM, 35 nM and 92 nM in HCT-116, HeLa and A375 cells, respectively). Synonyms: Cyclin-dependent Kinase 1/2 Inhibitor III; 1H-1,2,4-Triazole-1-carbothioamide, 3-amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-; 3-Amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide; 3-amino-N-(2,6-difluorophenyl)-5-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide. Grade: >95%. CAS No. 443798-55-8. Molecular formula: C15H13F2N7O2S2. Mole weight: 425.44. | |
| Cdk1/2 Inhibitor III - CAS 443798-55-8 | The Cdk1/2 Inhibitor III, also referenced under CAS 443798-55-8, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Cdk1/2 Inhibitor II, NU6102 - CAS 444722-95-6 | The Cdk1/2 Inhibitor II, NU6102, also referenced under CAS 444722-95-6, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Cdk1/5 Inhibitor - CAS 40254-90-8 | The Cdk1/5 Inhibitor, also referenced under CAS 40254-90-8, controls the biological activity of Cdk1/5. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| CDK1/CyclinA1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| CDK1/Cyclin A2, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| CDK1/CyclinB1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| CDK1 Inhibitor | Cdk1 inhibitor is a cell-permeable indolylmethylene-2-indolinone derivative that exhibits potent anti-proliferative properties with IC50 of 2 μM. Cdk1 inhibitor acts as a selective and ATP-competitive inhibitor of Cdk1/cyclin B with IC50 of 5.8 μM. It also inhibits Cdk5 with IC50 of 25 μM. Synonyms: Cyclin-dependent Kinase 1 Inhibitor. Grade: ≥95%. CAS No. 220749-41-7. Molecular formula: C17H11ClN2O. Mole weight: 294.7. | |
| Cdk1 Inhibitor - CAS 220749-41-7 | The Cdk1 Inhibitor, also referenced under CAS 220749-41-7, controls the biological activity of Cdk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Cdk1 Inhibitor IV, RO-3306 | RO-3306 is a cell-permeable, potent and ATP-competitive inhibitor of Cdk1 (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| cdk1, phosphorylated (Thr14, Tyr15) Negative Control Peptide (Non-Phosphorlyated) | cdk1, phosphorylated (Thr14, Tyr15) Negative Control Peptide (Non-Phosphorlyated). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
| cdk1, phosphorylated (Thr14, Tyr15) Positive Control Peptide (Phosphorlyated) | cdk1, phosphorylated (Thr14, Tyr15) Positive Control Peptide (Phosphorlyated). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
| CDK2 | CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. Synonyms: Cell division protein kinase 2; kinase Cdk2; p33 protein kinase; Anti-Gastric receptor I; Anti-H2R; His-His-Ala-Ser-Pro-Arg-Lys; L-histidyl-L-histidyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-lysine. Grade: ≥95%. CAS No. 255064-79-0. Molecular formula: C35H57N15O9. Mole weight: 831.92. | |
| CDK2 | CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S 0 /T 0 ) in a protein substrate. Uses: Scientific research. Group: Peptides. CAS No. 255064-79-0. Pack Sizes: 5 mg. Product ID: HY-P0235. | |
| Cdk2/9 Inhibitor | Cdk2/9 inhibitor is an inhibitor used for the synthesis of Nek1 inhibitors BSc5231 and BSc5367. Synonyms: CK7; 4-(2-Amino-4-methyl-5-thiazolyl)-N-(3-nitrophenyl)-2-pyrimidinamine; [4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl](3-nitrophenyl)amine; 4-(2-Amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)-2-pyrimidinamine. Grade: 95%. CAS No. 507487-89-0. Molecular formula: C14H12N6O2S. Mole weight: 328.34. | |
| Cdk2/9 Inhibitor - CAS 507487-89-0 | The Cdk2/9 Inhibitor, also referenced under CAS 507487-89-0, controls the biological activity of Cdk2/9. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| CDK2 acetate | CDK2 acetate, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Synonyms: H-His-His-Ala-Ser-Pro-Arg-Lys-OH.CH3CO2H; L-histidyl-L-histidyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-lysine acetic acid. Grade: ≥95%. Molecular formula: C37H61N15O11. Mole weight: 891.99. | |
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