American Chemical Suppliers
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Product | Description | |
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CDDO-DhTFEA Quick inquiry Where to buy Suppliers range | CDDO-DhTFEA can effectively activate Nrf2 and inhibit the pro-inflammatory transcription factor NF-κB. Synonyms: RTA Dh404; RTA Dh404RTA Dh404. CAS No. 1191265-33-4. Molecular formula: C33H45F3N2O3. Mole weight: 574.7. | |
CDDO-EA Quick inquiry Where to buy Suppliers range | CDDO-EA is an activator of Nrf2/ARE. It has neuroprotective effect. Synonyms: CDDO ethyl amide; RTA405; TP319; RTA 405; TP 319; RTA-405; TP-319. Grades: >98%. CAS No. 932730-51-3. Molecular formula: C33H46N2O3. Mole weight: 518.73. | |
CDDO Im Quick inquiry Where to buy Suppliers range | CDDO Im. Group: Biochemicals. Grades: Purified. CAS No. 443104-02-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CDDO Imidazolide Quick inquiry Where to buy Suppliers range | CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers. Group: Biochemicals. Alternative Names: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; CDDO-Im; RTA 403; TP 235. Grades: Highly Purified. CAS No. 443104-02-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
CDDO Imidazolide Quick inquiry Where to buy Suppliers range | CDDO Imidozolide is a synthetic triterpenoid as a Nrf2 signaling activator with highly active in suppressing cellular proliferation of human leukemia and breast cancer cell. Uses: Nrf2 signaling activator. Synonyms: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile. Grades: ≥98 %. CAS No. 443104-02-7. Molecular formula: C34H43N3O3. Mole weight: 541.72. | |
CDDO-Me (NSC 713200, Bardoxolone Methyl, BARD, Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate) Quick inquiry Where to buy Suppliers range | A cell-permeable, bioavailable synthetic oleanane triterpenoid compound with anti-inflammatory, anti-tumor and cytoprotective properties. Shown to significantly reduce the expression of several inflammatory mediators, including IL-6, IL-10, IL-12, TNFalpha, Mip1alpha and others. Reverses high fat diet-induced type 2 diabetes in C57BL/6 mice (3mg/kg) and improves glucose homeostasis and insulin sensitivity. Down-regulates lipogenic gene expression in hepatocytes. Exhibits anti-proliferative activity in osteosarcoma cells (IC50 = 800, 150, 330, and 170nM in HOB-c, KHOS, KHOSR2, and U2OS cells, respectively). Enhances the effectiveness of chemotherapeutic agents by inducing intrinsic mitochondrial-dependent apoptotic pathway. Reported to interact with multi cellular targets, namely, Nrf2-Keap1, IKK, JAK-STAT, PPARg, ErbB2, PTEN, mTOR and Arp3 and covalently modify active site Cys residue via Michael addition. Group: Biochemicals. Grades: Highly Purified. CAS No. 218600-53-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CDDO Methyl Ester Quick inquiry Where to buy Suppliers range | CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer. Group: Biochemicals. Alternative Names: 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402. Grades: Highly Purified. CAS No. 218600-53-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CDDO-TFEA Quick inquiry Where to buy Suppliers range | CDDO-TFEA is an Nrf2/ARE pathway activator. CDDO-TFEA inhibits BACH1 via reducing BACH1 nuclear levels while accumulating its cytoplasmic form. Synonyms: 2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-oleana-1,9(11)-dien-28-amide; CDDO-trifluoroethyl-amide. CAS No. 932730-52-4. Molecular formula: C33H43F3N2O3. Mole weight: 572.7. | |
CDDU-Me Quick inquiry Where to buy Suppliers range | CDDU-Me is an activator of the Nrf2 pathway, which induces the expression of cytoprotective genes regulated by Nrf-2 in vivo. It has anti-inflammatory, anti-tumor and cell protection properties. Synonyms: AC-31539. CAS No. 1616932-17-2. Molecular formula: C32H43NO4. Mole weight: 505.7. | |
C-Demethyl clethodim Quick inquiry Where to buy Suppliers range | C-Demethyl clethodim. Group: Biochemicals. Alternative Names: (E) -2-[1-[[ (3-Chloro-2-propenyl) oxy]imino]ethyl]-5-[2- (ethylthio) propyl]-1, 3-cyclohexanedione. Grades: Highly Purified. CAS No. 112301-96-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H24ClNO3S. US Biological Life Sciences. | Worldwide |
c-Desmethyl metoprolol Quick inquiry Where to buy Suppliers range | c-Desmethyl metoprolol. Group: Heterocyclic Organic Compound. Alternative Names: 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol; H 173/09. CAS No. 109632-08-8. Product ID: ACM109632088. Molecular formula: C14H23NO3. Mole weight: 253.34. Appearance: Off-White Solid. | |
C-Desmethyl Metoprolol Quick inquiry Where to buy Suppliers range | A new byproduct detected in Metoprolol tartrate. Group: Biochemicals. Alternative Names: 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol; H 173/09. Grades: Highly Purified. CAS No. 109632-08-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CDi(1-adamantyl)-n-butylphosphine Quick inquiry Where to buy Suppliers range | CDi(1-adamantyl)-n-butylphosphine. Group: Biochemicals. Alternative Names: Cataxium A. Grades: Highly Purified. CAS No. 321921-71-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C24H39P. US Biological Life Sciences. | Worldwide |
c-di-2'-d-2''-O-Me-AMP Quick inquiry Where to buy Suppliers range | c-di-2'-d-2''-O-Me-AMP is an analogue of c-diAMP, the bacterial second messenger. Synonyms: 2'- Deoxy- 2''- O- methyl- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H26N10O11P2 (free acid). Mole weight: 656.5 (free acid). | |
c-di-2'-dAMP Quick inquiry Where to buy Suppliers range | c-di-2'-dAMP is an analogue of c-diAMP, the bacterial second messenger. Synonyms: 2'- Deoxy- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O11P2 (free acid). Mole weight: 642.4 (free acid). | |
c-di-2'-dGMP Quick inquiry Where to buy Suppliers range | c-di-2'-dGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions. Synonyms: 2'- Deoxy- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 132182-18-4. Molecular formula: C20H24N10O13P2 (free acid). Mole weight: 674.4 (free acid). | |
c-di-AMP Quick inquiry Where to buy Suppliers range | c-di-AMP is an agonist of stimulator of interferon genes (STING) for treating cancer. It is a second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance, and other functions. Synonyms: Cyclic diadenylate monophosphate; Cyclic diadenylate; Adenylic acid, cyclic ester; 3',5'-Cyclic diadenylic acid; Cyclic di-3',5'-adenylate; Cyclic di-AMP; Cyclic-di-AMP; Cyclic diadenosine monophosphate; (2R, 3R, 3aS, 7aR, 9R, 10R, 10aS, 14aR)-2, 9-bis(6-amino-9H-purin-9-yl)-3, 5, 10, 12-tetrahydroxyoctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecine 5,12-dioxide. Grades: ≥95%. CAS No. 54447-84-6. Molecular formula: C20H24N10O12P2. Mole weight: 658.41. | |
CDIBA Quick inquiry Where to buy Suppliers range | CDIBA is a potent and selective cytosolic phospholipase A2 (cPLA2) inhibitor. Synonyms: 4-[2-(1-benzhydryl-5-chloro-2-methylindol-3-yl)ethoxy]benzoic acid. Grades: 99%. CAS No. 479422-22-5. Molecular formula: C31H26ClNO3. Mole weight: 496. | |
c-Di-GMP Quick inquiry Where to buy Suppliers range | c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'?5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP. Grades: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41. | |
c-di-GMP Fluorinated Quick inquiry Where to buy Suppliers range | A STING agonist. CAS No. 1334145-18-4. Molecular formula: C20H20F2N10O12P2.2Na. Mole weight: 738.36. | |
c-di-IMP Quick inquiry Where to buy Suppliers range | c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination. Synonyms: Cyclic diinosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79940-41-3. Molecular formula: C20H22N8O14P2 (free acid). Mole weight: 660.4 (free acid). | |
C-DIM12 Quick inquiry Where to buy Suppliers range | C-DIM12 is a novel synthetic activator of Nurr1. C-DIM12 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Synonyms: C-DIM12; C-DIM 12; C-DIM-12. Grades: 98%. CAS No. 178946-89-9. Molecular formula: C23H17ClN2. Mole weight: 356.85. | |
c-di-UMP Quick inquiry Where to buy Suppliers range | A STING agonist negative control. Synonyms: Cyclic di-uridine monophosphate, c-di-UMP sodium salt. CAS No. 73120-97-5. Molecular formula: C18H20N4O16P2.2Na. Mole weight: 656.3. | |
Cdk1/2 inhibitor iii Quick inquiry Where to buy Suppliers range | White solid. Group: Heterocyclic Organic Compound. Alternative Names: Cdk1/2 Inhibitor III, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, 5-Amino-3-((4-(aminosulfonyl)phenyl)amino)-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide, 2wu6, AC1NS9OB, CDK 1/2 INHIBITOR, CHEMBL261720, CTK8E9250, HMS3229C16, CCG-206824, DB07664, K00546, 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n, 5-amino-N-(2,6-difluorophenyl)-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbothioamide, 443798-55-8, 5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1,2,4-triazole-1-carbothioamide. Grades: >95%. CAS No. 443798-55-8. Molecular formula: C15H13F2N7O2S2. Mole weight: 425.4. IUPAC Name: 5-amino-N-(2,6-difluorophenyl)-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbothioamide. Exact Mass: 425.05400. InChIKey: ARIOBGGRZJITQX-UHFFFAOYSA-N. H-Bond Donor: 4. H-Bond Acceptor: 10. | |
CDK1/2 Inhibitor III Quick inquiry Where to buy Suppliers range | Cdk1/2 Inhibitor III is a selective inhibitor of Cdk1/2 with an IC50 of 2.1 μM for CDK1/cyclin B. It is a cell-permeable triazolo-diamine compound with anti-proliferative properties in various human cancer cells (IC50 = 20 nM, 35 nM and 92 nM in HCT-116, HeLa and A375 cells, respectively). Synonyms: Cyclin-dependent Kinase 1/2 Inhibitor III; 1H-1,2,4-Triazole-1-carbothioamide, 3-amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-; 3-Amino-5-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide; 3-amino-N-(2,6-difluorophenyl)-5-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide. Grades: >95%. CAS No. 443798-55-8. Molecular formula: C15H13F2N7O2S2. Mole weight: 425.44. | |
Cdk1/2 Inhibitor III - CAS 443798-55-8 Quick inquiry Where to buy Suppliers range | The Cdk1/2 Inhibitor III, also referenced under CAS 443798-55-8, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 443798-55-8. Pack Sizes: 1MG. Mole weight: 425.44. Catalog: AP443798558. Assay: ≥95% (HPLC). | |
Cdk1/2 Inhibitor II, NU6102 - CAS 444722-95-6 Quick inquiry Where to buy Suppliers range | The Cdk1/2 Inhibitor II, NU6102, also referenced under CAS 444722-95-6, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 444722-95-6. Pack Sizes: 1MG, 5MG. Mole weight: 402.47. Catalog: AP444722956. Assay: ≥95% (HPLC). | |
Cdk1/5 Inhibitor - CAS 40254-90-8 Quick inquiry Where to buy Suppliers range | The Cdk1/5 Inhibitor, also referenced under CAS 40254-90-8, controls the biological activity of Cdk1/5. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 40254-90-8. Pack Sizes: 5MG. Mole weight: 185.19. Catalog: AP40254908. Assay: ≥95% (HPLC). | |
CDK1 Inhibitor Quick inquiry Where to buy Suppliers range | Cdk1 inhibitor is a cell-permeable indolylmethylene-2-indolinone derivative that exhibits potent anti-proliferative properties with IC50 of 2 μM. Cdk1 inhibitor acts as a selective and ATP-competitive inhibitor of Cdk1/cyclin B with IC50 of 5.8 μM. It also inhibits Cdk5 with IC50 of 25 μM. Synonyms: Cyclin-dependent Kinase 1 Inhibitor. Grades: ≥95%. CAS No. 220749-41-7. Molecular formula: C17H11ClN2O. Mole weight: 294.7. | |
Cdk1 Inhibitor IV, RO-3306 Quick inquiry Where to buy Suppliers range | RO-3306 is a cell-permeable, potent and ATP-competitive inhibitor of Cdk1 (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 5MG. Mole weight: 351.45. Catalog: IAR42417796. Assay: ≥95% (HPLC). | |
cdk1, phosphorylated (Thr14, Tyr15) Negative Control Peptide (Non-Phosphorlyated) Quick inquiry Where to buy Suppliers range | cdk1, phosphorylated (Thr14, Tyr15) Negative Control Peptide (Non-Phosphorlyated). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
cdk1, phosphorylated (Thr14, Tyr15) Positive Control Peptide (Phosphorlyated) Quick inquiry Where to buy Suppliers range | cdk1, phosphorylated (Thr14, Tyr15) Positive Control Peptide (Phosphorlyated). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
CDK2 Quick inquiry Where to buy Suppliers range | CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Uses: Peptide Inhibitors. CAS No. 255064-79-0. Product ID: R1272. | |
CDK2 Quick inquiry Where to buy Suppliers range | CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. Synonyms: Cell division protein kinase 2; kinase Cdk2; p33 protein kinase; Anti-Gastric receptor I; Anti-H2R; His-His-Ala-Ser-Pro-Arg-Lys; L-histidyl-L-histidyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-lysine. Grades: ≥95%. CAS No. 255064-79-0. Molecular formula: C35H57N15O9. Mole weight: 831.92. | |
Cdk2/9 Inhibitor - CAS 507487-89-0 Quick inquiry Where to buy Suppliers range | The Cdk2/9 Inhibitor, also referenced under CAS 507487-89-0, controls the biological activity of Cdk2/9. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 507487-89-0. Pack Sizes: 5MG. Mole weight: 328.35. Catalog: AP507487890. Assay: ≥95% (HPLC). | |
CDK2 acetate Quick inquiry Where to buy Suppliers range | CDK2 acetate, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Synonyms: H-His-His-Ala-Ser-Pro-Arg-Lys-OH.CH3CO2H; L-histidyl-L-histidyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-lysine acetic acid. Grades: ≥95%. Molecular formula: C37H61N15O11. Mole weight: 891.99. | |
CDK2 inhibitor II Quick inquiry Where to buy Suppliers range | CDK2 inhibitor II. Group: Biochemicals. Alternative Names: 4- [2- (5-Bromo-1, 2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazinyl] benzenesulfonamide; 4- [ (5-Bromo-1, 2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazino] benzenesulfonamide; SC 221409. Grades: Highly Purified. CAS No. 222035-13-4. Pack Sizes: 5mg. Molecular Formula: C14H11BrN4O3S, Molecular Weight: 395.23. US Biological Life Sciences. | Worldwide |
CDK2 Inhibitor II Quick inquiry Where to buy Suppliers range | The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G2-M transition during the cell cycle. Cdk2 Inhibitor II is a potent, cell-permeable, ATP-competitive, and selective inhibitor of Cdk2. It is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 with IC50 of 60 nM. Synonyms: Cyclin-dependent kinase 2 Inhibitor II; SC-221409. Grades: ≥95%. CAS No. 222035-13-4. Molecular formula: C14H11BrN4O3S. Mole weight: 395.2. | |
CDK4/6 Inhibitor IV Quick inquiry Where to buy Suppliers range | Cdk4/6 inhibitor IV is a cell-permeable triaminopyrimidine inhibitor for Cdk4/cyclin D1 with IC50 values of 1.5 μM and Cdk6/cyclin D1 with IC50 values of 5.6 μM. It exhibits blocking of pRb phosphorylation at Ser780 and Ser795. Cdk4/6 inhibitor IV can suppresses tumor growth in Xenograft mouse model. Synonyms: CINK4; Cyclin-dependent kinase 4/6 Inhibitor IV. Grades: ≥98%. CAS No. 359886-84-3. Molecular formula: C27H32N6O. Mole weight: 456.6. | |
CDK4-IN-1 Quick inquiry Where to buy Suppliers range | CDK 4/6 Inhibitor is a part of a group of compounds that exhibits selective inhibitory properties towards Cyclin-Dependent Kinases 4 & 6. These compounds are most commonly used to treat patients with breast cancer. Synonyms: CDK4 IN 1; LEE011 analog; CDK4-IN-1; CDK4IN-1; CDK4-IN1; CDK4IN1; CDK4 IN 1; 4-[5-Chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-2-pyrimidinamine. Grades: >98%. CAS No. 1256963-02-6. Molecular formula: C22H29ClN8. Mole weight: 440.97. | |
CDK4 Inhibitor Quick inquiry Where to buy Suppliers range | Cdk4 inhibitor is a cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by blocking cyclin D1/Cdk4 with an IC50 of 0.8 μM. It also inhibits the activity of other Cdk's only at much higher concentrations (IC50 = 520 nM and 2.1 μM for Cdk2/E and Cdk1/B, respectively). Cdk4 inhibitor can inhibit tumor cells growth in HCT-116 and NCI-H460 cells (IC50 < 3.0 μM). Synonyms: 2-Bromo-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grades: ≥90%. CAS No. 546102-60-7. Molecular formula: C20H10BrN3O2. Mole weight: 404.22. | |
Cdk4 Inhibitor V (4-(((4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino)-methylene)-6-iodo-4H-isoquinoline-1,3-dione) Quick inquiry Where to buy Suppliers range | A cell-permeable pyridinylmethylamino-isoquinoline dione compound that acts as a potent, ATP-binding site targeting and reversible inhibitor of Cdk4/D1 activity with selectivity over Cdk2/E and Cdk1/B (IC50=0.03, 1.6 and 25.3uM, respectively). Shown to block the phosphorylation of Rb and induce growth arrest in HCT116 and MCF-7 cells (IC50=0.73 and 0.88uM). Displays desirable metabolic stability in rat liver microsomes and in the presence of NADPH and UDPGA cofactors (t1/2 > 30mins). Group: Biochemicals. Grades: Highly Purified. CAS No. 943746-57-4. Pack Sizes: 5mg. Molecular Formula: C??H??IN?O?. US Biological Life Sciences. | Worldwide |
CDK4-R24C Quick inquiry Where to buy Suppliers range | Cyclin-dependent kinase 4. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-016. | |
CDK9-IN-1 Quick inquiry Where to buy Suppliers range | Among CDKs, CDK9 is a validated pathological target in HIV infection, inflammation and cardiac hypertrophy; however selective CDK9 inhibitors are still not available. We present a selective inhibitor family of CDK9 based on the 4-phenylamino-6- phenylpyrimidine nucleus. We show a convenient synthetic method to prepare a useful intermediate and its derivatisation resulting in novel compounds. The CDK9 inhibitory activity of the derivatives was measured in specific kinase assay and the CDK inhibitory profile of the best ones (IC50 > 100nM) was determined. The most selective compounds had high selectivity over CDK1, 2, 3, 5, 6, 7 and showed at least one order of magnitude higher inhibitory activity over CDK4 inhibition. The most selective molecules were examined in cytotoxicity assays and their ability to inhibit HIV-1 replication was determined in cellular assays. Synonyms: CDK9-IN-1; CDK9 IN 1. Grades: >98%. CAS No. 1415559-43-1. Molecular formula: C26H21N5O4S. Mole weight: 499.54. | |
CDK9-IN-2 Quick inquiry Where to buy Suppliers range | CDK9-IN-2 is a novel cyclin-dependent kinase 9(CDK9) inhibitor. Synonyms: CDK9 Inhibitor II; CDK9 Inhibitor 2; CDK9-In-2; CDK9-IN2. Grades: >98%. CAS No. 1263369-28-3. Molecular formula: C23H25ClFN5. Mole weight: 425.93. | |
CDK9-IN-6 Quick inquiry Where to buy Suppliers range | CDK9-IN-6, one of the CDK9 inhibitors, probably have potential activity in influencing cell cycle of T-type cells. Uses: Cdk9-in-6 is one of the cdk9 inhibitors that probably have potential activity in influencing cell cycle of t-type cells. Synonyms: CDK9-IN-6; SCHEMBL12466375; SCHEMBL15378321; SCHEMBL15378323; CS-4615; CS 4615; CS4615. Grades: 98%. CAS No. 1391855-95-0. Molecular formula: C27H37ClN6O2. Mole weight: 513.08. | |
CDK/CRK Inhibitor Quick inquiry Where to buy Suppliers range | CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM. It is also a potent, selective & ATP-competitive inhibitor of CDKs. CDK/CRK inhibitor exhibits less than 20% inhibition of 60 non-CDK/CRK kinases at 1 μM. Synonyms: Cdk7 Inhibitor IV; Cyclin-dependent kinase 7 Inhibitor IV; Cyclin-dependent kinase/CDK-related kinase Inhibitor; RGB-286147; RGB 286147. Grades: ≥98%. CAS No. 784211-09-2. Molecular formula: C23H22Cl2N4O3. Mole weight: 473.4. | |
Cdk/Crk Inhibitor - CAS 784211-09-2 Quick inquiry Where to buy Suppliers range | The Cdk/Crk Inhibitor, also referenced under CAS 784211-09-2, controls the biological activity of Cdk/Crk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 784211-09-2. Pack Sizes: 1MG. Mole weight: 473.35. Catalog: AP784211092. Assay: ≥95% (HPLC). | |
CDKI-73 Quick inquiry Where to buy Suppliers range | CDKI-73 was cytotoxic to all of the CLL samples tested (n = 38) with a mean LD50 value of 0.08μM ± 0.10 μM following exposure to drug for 48h. In contrast, normal B-lymphocytes (n = 10) and CD34+ normal bone marrow cells (n = 5) were significantly less susceptible to the cytotoxic effects of CDKI-73. Treatment of CLL cells with 0.1 μM CDKI-73 for 4h inhibited the phosphorylation of cdk9 and ser2 of RNA polymerase II. CDKI-73 induces a rapid loss of MCL1 protein and this is mediated by significant inhibition at the level of gene transcription. However, this inhibition is not restricted to MCL1 as similar reductions in XIAP and CCND2 were also observed following exposure to CDKI-73 for 4h. CDKI-73 rapidly inhibited cellular CDK9 kinase activity and down-regulated the RNAPII phosphorylation. CDK9 shRNA was also found to down-regulate the Mnk1 expression. Both CDKI-73 and CDK9 shRNA decreased anti-apoptotic proteins Mcl-1 and Bcl-2 and induced apoptosis. CDKI-73 exhibited a favorable pharmacokinetic profile with oral bioavailability of F=56% following a single intravenous bolus dose at 2 mg/kg and an oral dose at 10 mg/kg in mice. Synonyms: CDKI-73; CDKI 73; CDKI73. Grades: >98%. CAS No. 1421693-22-2. Molecular formula: C15H15FN6O2S2. Mole weight: 394.45. | |
CDKI-83 Quick inquiry Where to buy Suppliers range | CDKI-83 is a potent CDK9 inhibitor. The compound shows effective anti-proliferative activity in human tumour cell lines with GI50 <1 μM, and is capable of inducing apoptosis in A2780 human ovarian cancer cells as determined by the activated caspase-3, Annexin V/PI double staining and accumulated cells at the sub-G1 phase of cellcycle. The research results suggest that combined inhibition of CDK9 and CDK1 may result in the effective induction of apoptosis and CDKI-83 has the potential to be developed as an anti-cancer agent. Synonyms: CDKI83; CDKI 83. CAS No. 1189558-88-0. Molecular formula: C21H23N7O3S2. Mole weight: 485.58. | |
CDK-IN-2 Quick inquiry Where to buy Suppliers range | CDK-IN-2 is a potent and sepecific CDK inhibitor. Synonyms: CDK inhibitor II. Grades: >98%. CAS No. 1269815-17-9. Molecular formula: C18H19ClFN3O2. Mole weight: 363.81. | |
CDMT Quick inquiry Where to buy Suppliers range | It is a stable, crystalline compound, with good solubility in organic solvents, and is commercially available in large quantities. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 2-Chloro-4,6-dimethoxy-1,3,5-triazine. CAS No. 3140-73-6. | Luxembourg Bio Technologies |
CDN 1163 Quick inquiry Where to buy Suppliers range | CDN 1163 is an allosteric activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2), increasing Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. It reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. CDN 1163 has the potential to treat type-2 diabetes and metabolic dysfunction. Synonyms: CDN-1163; CDN 1163; CDN1163; 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide; 4-Isopropoxy-N-(2-methylquinolin-8-yl)benzamide. Grades: ≥98% by HPLC. CAS No. 892711-75-0. Molecular formula: C20H20N2O2. Mole weight: 320.38. | |
cDNA Library Quick inquiry Where to buy Suppliers range | cDNA Library Construction Service can Include: Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
cDNA Library, Vector Preparation Quick inquiry Where to buy Suppliers range | cDNA Library Construction Service Includes: Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
CDP 840 hydrochloride Quick inquiry Where to buy Suppliers range | CDP 840 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 162542-90-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
CDP 840 hydrochloride Quick inquiry Where to buy Suppliers range | CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC50 = 12 nM). It competitively inhibits all PDE4 isoenzymes. Synonyms: CDP840; CDP-840; CDP 840; CDP840 HCl; CDP840HCl. 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride. Grades: ≥98% by HPLC. CAS No. 162542-90-7. Molecular formula: C25H27NO2.HCl. Mole weight: 409.95. | |
CDP-β-S Quick inquiry Where to buy Suppliers range | CDP-β-S is a CDP binding proteins regulator with a higher stability. It is used for characterization of CDP-responsive receptors, determination of their stereospecificity and labelling with thio-reactive reporter groups. Synonyms: Cytidine- 5'- O- (2- thiodiphosphate), sodium salt. Grades: ≥ 95% by HPLC. CAS No. 497064-72-9. Molecular formula: C9H15N3O10P2S (free acid). Mole weight: 419.2 (free acid). | |
cDPCP Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), solid. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 106343-54-8. Pack Sizes: 5MG, 25MG. Mole weight: 379.14. Catalog: AP106343548. Assay: ≥98% (HPLC). | |
CDP-ethanolamine Quick inquiry Where to buy Suppliers range | CDP-ethanolamine, a pivotal intermediary in the biosynthesis of membrane phospholipids, assumes an indispensable function in preserving cellular membrane integrity. Clinical research evince that it ameliorates cognitive development in patients diagnosed with neurodegenerative conditions, notably Alzheimer's disease. Furthermore, it potentially mitigates glaucoma symptoms by diminishing intraocular pressure while enhancing blood flow, thereby ameliorating optic nerve functionality. Synonyms: Cytidine-5'-diphosphate ethanolamine; Cytidine-5'-diphosphateethanolamine. Grades: ≥ 95% by HPLC. CAS No. 3036-18-8. Molecular formula: C11H20N4O11P2. Mole weight: 446.25. | |
CDP-Gel / CDP-Agarose Quick inquiry Where to buy Suppliers range | CDP-Gel is the CDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of sialyltransferases. Synonyms: Cytidine- 5'- O- diphosphate, immobilized on a polymeric matrix. | |
CDPI3 MGB CPG Quick inquiry Where to buy Suppliers range | CDPI3 MGB CPG is an exquisitely tailored and purposeful compound that garners marked proficiency within the realm of biomedicine, and has demonstrated efficacy in addressing diverse manifestations of cancer. Its unique mechanism of action bespeaks its ability to regulate crucial enzymes involved in tumor expansion, exclaiming its aptitude for both solid tumors and leukemia. Moreover, corresponding research has unveiled the possibility of applying this compound as an efficacious treatment modality for autoimmune disorders. Synonyms: 5-(6-(6-(6-(6-Dimethoxytrityloxyhexanoyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxamido)pentyl-1-O-diglycoloyl long chain alkylamino CPG. Mole weight: 831.87. | |
CDP - lyophilized Quick inquiry Where to buy Suppliers range | CDP - lyophilized is a biomedical compound used in the research of neurological disorders. Substances like Cytidine-5'-diphosphate (CDP) function as a precursor to nucleotides, contributing to RNA and DNA enhancement. This lyophilized form offering improved stability and ensures optimal compound delivery. Synonyms: Cytidine-5'-diphosphate, Sodium salt. Grades: ≥ 96% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid). | |
CDPPB Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy; Pharmaceutical Toxicology. CAS No. 781652-57-1. Pack Sizes: 5MG, 25MG. IUPAC Name: 3-cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide. Molecular formula: C23H16N4O. Mole weight: 364.40. Catalog: APS781652571. Assay: ≥98% (HPLC). SMILES: O=C (Nc1cc (nn1c2ccccc2)c3ccccc3)c4cccc (c4)C#N. Format: Neat. | |
CDPPB Quick inquiry Where to buy Suppliers range | CDPPB is a positive allosteric modulator of mGlu5 receptor (EC50 = 10 and 20 nM for human and rat receptors, respectively). Study shows that CDPPB has a therapeutic effect for cognitive deficits in schizophrenia and pathology in Huntington's disease. CDPPB is a potential antipsychotic and nootropic drug. Synonyms: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide; 3-cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide. Grades: ≥98% by HPLC. CAS No. 781652-57-1. Molecular formula: C23H16N4O. Mole weight: 364.4. | |
CDPPB Quick inquiry Where to buy Suppliers range | CDPPB. Group: Biochemicals. Alternative Names: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide. Grades: Highly Purified. CAS No. 781652-57-1. Pack Sizes: 5mg. Molecular Formula: C23H16N4O, Molecular Weight: 364.4. US Biological Life Sciences. | Worldwide |
CdS CdSe Core Shell Nanoparticles Quick inquiry Where to buy Suppliers range | CdS CdSe Core Shell Nanoparticles. Grades: 99.9%. Product ID: ACMA00020031. | |
CdSe CdS Core Shell Nanoparticles Quick inquiry Where to buy Suppliers range | CdSe CdS Core Shell Nanoparticles. Grades: 99.9%. Product ID: ACMA00020033. | |
CdSe/CdS core-shell type quantum rods Quick inquiry Where to buy Suppliers range | CdSe/CdS core-shell type quantum rods. Group: Quantum Dots. | |
CdSe/CdS Core-shell Type Quantum Rods-530 nm Quick inquiry Where to buy Suppliers range | fluorescence λem 530 nm, 5 mg/mL in Hexane. Uses: CdSe/CdS quantum rods possess excellent optoelectronic properties such as tunable emission wavelength, high extinction coefficient, polarized emission, enhanced quantum yield and exhibit an order of magnitude higher brightness. These outstanding properties make the CdSe/CdS nanorods suitable for applications such as displays, solid state lighting (LED) and lasers as these require strong fluorescence. Group: CdSe/CdS Core-shell Type Quantum Rods. Alternative Names: Elongated Quantum Dots, CANdot, Quantum Dots, Fluorescent nanocrystals, Quantum rods. |