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| Product | Description | |
|---|---|---|
| CBP/p300 ligand 2 | CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2484741-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138539. |  |
| CBP-V | CBP-V. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9'-([1,1'-Biphenyl]-4,4'-diyl)bis(3-ethenyl-9H-carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 908147-48-8. Molecular formula: C40H28N2. Mole weight: 536.66 g/mol. Product ID: ACM908147488. Alfa Chemistry ISO 9001:2015 Certified. Categories: CBPV. |  |
| CBR-470-1 | CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416095-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134205A. | |
| CBR 5884 | CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases. Uses: 3-phosphoglycerate dehydrogenase (phgdh) inhibitor. Synonyms: CBR-5884; CBR 5884; CBR5884. Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate. Grades: ≥98%. CAS No. 681159-27-3. Molecular formula: C14H12N2O4S2. Mole weight: 336.39. |  |
| CBR-5884 | CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 ?M. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 681159-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100012. | |
| CBR-5884 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CBS1117 | CBS1117 is an effective inhibitor of influenza A virus entry, which can inhibit influenza virus hemagglutinin. Synonyms: 2,6-Dichloro-N-[1-(Propan-2-Yl)Piperidin-4-Yl]Benzamide. Grades: 98%. CAS No. 959245-08-0. Molecular formula: C15H20Cl2N2O. Mole weight: 315.2. | |
| CBS9106 (BMS566419) | Cas No. 1076235-04-5. | |
| CBS, N-Cyclohexyl -2-benzothiazolesulfenami de | CBS, N-Cyclohexyl -2-benzothiazolesulfenami de . Group: Biochemicals. Grades: Highly Purified. CAS No. 95-33-0. Pack Sizes: 250g, 500g. US Biological Life Sciences. |  Worldwide |
| Cbz-1-amino-1-cyclooctanecarboxylic acid | Cbz-1-amino-1-cyclooctanecarboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-1-AMINO-1-CYCLOOCTANECARBOXYLIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 175407-63-3. Molecular formula: C17H23NO4. Mole weight: 305.37. Purity: 0.96. IUPACName: 1-(phenylmethoxycarbonylamino)cyclooctane-1-carboxylate. Canonical SMILES: C1CCCC(CCC1)(C(=O)O)NC(=O)OCC2=CC=CC=C2. Product ID: ACM175407633. Alfa Chemistry ISO 9001:2015 Certified. | |
| CBZ-8-amino-3,6-dioxaoctanoic acid | CBZ-8-amino-3,6-dioxaoctanoic acid. Group: Polymers. CAS No. 16545-06-8. |  |
| CBZ-9-amino-4,7-dioxanonanoic acid | CBZ-9-amino-4,7-dioxanonanoic acid. Group: Polymers. CAS No. 462100-05-6. | |
| Cbz-allo-thr(tbu)-oh·dcha | Cbz-allo-thr(tbu)-oh·dcha. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 198828-94-3, Z-Allo-thr(tbu)-oh dcha, MolPort-020-004-628, AKOS015911533, AK105242, B-7696, I14-37239, Dicyclohexylamine (2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)butanoate. Product Category: Heterocyclic Organic Compound. CAS No. 198828-94-3. Molecular formula: C28H46N2O5. Mole weight: 490.68. Purity: 0.96. IUPACName: N-cyclohexylcyclohexanamine;(2S,3S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoic acid. Product ID: ACM198828943. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cbz-B3A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Cbz-b-Alanine | Cbz-b-Alanine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2304-94-1. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Cbz-beta-amino-L-alanine tert-butyl ester hydrochloride | Cbz-beta-amino-L-alanine tert-butyl ester hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS022181690, AK-62642, (S)-tert-Butyl 3-amino-2-(((benzyloxy)carbonyl)amino)propanoate hydrochloride, 174796-88-4. Product Category: Heterocyclic Organic Compound. CAS No. 174796-88-4. Molecular formula: C15H23ClN2O4. Mole weight: 330.807120 [g/mol]. Purity: 0.96. IUPACName: tert-butyl (2S)-3-amino-2-(phenylmethoxycarbonylamino)propanoate;hydrochloride. Product ID: ACM174796884. Alfa Chemistry ISO 9001:2015 Certified. Categories: H-L-Dap(Z)-OtBu HCl. | |
| Cbz-Cyclohexyl-L-glycine | A gylicine derivative used in the preparation of peptides as inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4A protease. Group: Biochemicals. Alternative Names: (α S) -α - [ [ (Phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid; (S) -α - [ [ (phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 69901-75-3. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Cbz-D-Aze-OH | Synonyms: Z-D-Azetidine-2-Carboxylic acid; Cbz D Aze OH. CAS No. 25654-51-7. Molecular formula: C12H13NO4. Mole weight: 235.24. | |
| Cbz-D-(-)-Phenylglycine | Cbz-D-(-)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 17609-52-8. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Cbz-Glu-Trp-OH | Synonyms: Cbz Glu Trp OH; Z-Glu-Trp; (S)-4-(((benzyloxy)carbonyl)amino)-5-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid. CAS No. 73170-51-1. Molecular formula: C24H25N3O7. Mole weight: 467.47. | |
| Cbz-glycine | Cbz-glycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1138-80-3. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Cbz-glycine hydrazide | Cbz-glycine hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 5680-83-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Cbz-glycine methyl ester | Cbz-glycine methyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 1212-53-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Cbz-L-Aspartic 4-tert-butyl ester | Cbz-L-Aspartic 4-tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 5545-52-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C16H21NO6. US Biological Life Sciences. | Worldwide |
| Cbz-L-β-homoAsp(otBu)-OH | Cas No. 83436-45-7. Molecular formula: C17H23NO6. Mole weight: 337.4. | |
| Cbz-L-glutamine | Cbz-L-glutamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2650-64-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences. | Worldwide |
| Cbz-L-hydroxyproline | Cbz-L-hydroxyproline. Group: Biochemicals. Grades: Highly Purified. CAS No. 13504-85-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Cbz-L-Isoleucine dicyclohexylamine salt | Cbz-L-Isoleucine dicyclohexylamine salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 26699-00-3. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C26H42N2O4. US Biological Life Sciences. | Worldwide |
| Cbz-L-(+)-Phenylglycine | Cbz-L-(+)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53990-33-3. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| Cbz-L-pyroglutamic acid | Cbz-L-pyroglutamic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 32159-21-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H13NO5. US Biological Life Sciences. | Worldwide |
| Cbz-L-tert-Leucine | Leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors. Group: Biochemicals. Alternative Names: 3-Methyl-N-[ (phenylmethoxy) carbonyl]-L-valine; N-Carbobenzoxy-(S)-tert-leucine; 2S-Benzyloxycarbonylamino-3,3-dimethylbutyric Acid; Z-L-tert-Leucine; Benzyloxycarbonyl-L-tert-leucine; N-(Benzyloxycarbonyl)-L-tert-butylglycine; N-Benzyloxycarbonyl-L-tert-leucine; N-Benzyloxycarbonyl-tert-leucine. Grades: Highly Purified. CAS No. 62965-10-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| CBZ-L-Valine | N-Carbobenzyloxy-L-valine. Abacavir intermediate. CAS No. 1149-26-4. Product ID: 8-04591. Molecular formula: C13H11NO4. Mole weight: 251.28. Purity: 0.99. |  |
| Cbz-N-amido-PEG6-acid | Cbz-N-amido-PEG6-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 1334177-80-8. Molecular formula: C23H37NO10. Mole weight: 487.24. Purity: 95%+. Product ID: ACM1334177808. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cbz-neuraminic acid | Cbz-neuraminic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-NEURAMINIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 17367-66-7. Molecular formula: C17H23NO10. Mole weight: 401.37. Purity: 0.96. Product ID: ACM17367667. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cbz-O-methyl-L-ser | Cbz-O-methyl-L-ser. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-L-SERINE(METHYL ETHER);CBZ-O-METHYL-L-SER;CBZ-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 134807-65-1. Molecular formula: C12H15NO5. Mole weight: 253.25. Product ID: ACM134807651. Alfa Chemistry ISO 9001:2015 Certified. | |
| CC0651 | CC0651, a Cdc34 ubiquitin-conjugating enzyme allosteric inhibitor, has been found to restrain the cell proliferation at some extent in cancer cell lines PC-3. IC50: 1.72 uM (inhibited the ubiquitination of p27 Kip1). Uses: Cc0651 is a cdc34 ubiquitin-conjugating enzyme allosteric inhibitor that has been found to restrain the cell proliferation at some extent in cancer cell lines pc-3. ic50: 1.72 um (inhibited the ubiquitination of p27 kip1). Synonyms: CC0651;CC 0651; CC-0651; (2R, 3S, 4S)-5-[4-(3, 5-dichlorophenyl)phenyl]-2, 3-dihydroxy-4-[(2-methoxyacetyl)amino]pentanoicacid; CC0651; 1319207-44-7; 4, 5-Dideoxy-5-(3', 5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-ArabinonicAcid; U94; SCHEMBL14884531. Grades: 95%. CAS No. 1319207-44-7. Molecular formula: C20H21Cl2NO6. Mole weight: 442.29. | |
| CC-1065 | CC-1065 is originally isolated from Streptomyces zelensis and its bioactivity was very strong. CC-1065 is against gram-positive bacteria with the MIC=1-10 ng/mL, against most gram-negative bacterial and fungi with the MIC of 1 μg/mL. Synonyms: Antibiotic CC 1065; NSC298223; CCRIS 2174. CAS No. 69866-21-3. Molecular formula: C37H33N7O8. Mole weight: 703.70. | |
| CC-1088 | CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). Uses: Cytokine inhibitor. Synonyms: CC1088; CC 1088; CC-1088. 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamide. Grades: ≥98%. CAS No. 467421-06-3. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| CC-115 | CC-115, a DNA-PK and mTOR inhibitor, has been found to have probable anticarcinoma effect. IC50:13 nM and 21 nM for DNA-PK and mTOR respectively. Uses: Cc-115 is a dna-pk and mtor inhibitor and has been found to have probable anticarcinoma effect. Synonyms: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one; CC115 ; CC-115; CC 115. Grades: 98%. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.35. | |
| CC-115 | CC-115 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228013-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16962. | |
| CC-115 | CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CC115 ; CC-115; CC 115. Product Category: Inhibitors. Appearance: Red solid powder. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.14. Purity: >98%. IUPACName: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one. Canonical SMILES: O=C1CNC2=NC=C(C3=CC=C(C4=NC=NN4)N=C3C)N=C2N1CC. Product ID: ACM1228013157. Alfa Chemistry ISO 9001:2015 Certified. | |
| CC-115 hydrochloride | The hydrochloride salt form of CC-115 which is a mTOR / DNA-PK inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. IC50: 21 nM and 13 nM for mTOR and DNA-PK respectively. Uses: The hydrochloride salt form of cc-115 which is a mtor / dna-pk inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. Synonyms: CC115 hydrochloride ; CC-115 hydrochloride; CC 115 hydrochloride. Grades: 98%. CAS No. 1300118-55-1. Molecular formula: C16H17ClN8O. Mole weight: 372.81. | |
| CC-12074 | A Metabolite of Pomalidomide. Uses: Pomalidomide metabolite. Synonyms: CC-12074; CC12074; CC 12074; Pomalidomide metabolite M19; UNII-A480CC1Z8I; SCHEMBL3742152.4-amino-2-(5-hydroxy-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Grades: ≥98%. CAS No. 460741-57-5. Molecular formula: C13H11N3O5. Mole weight: 289.24. | |
| CC122 | CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial. Uses: Cc122 has antitumor and immunomodulatory activity. it is used for the treatment of chronic lymphocytic leukemia. Synonyms: 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione;CC-122; CC122; CC 122. Grades: >98 %. CAS No. 1015474-32-4. Molecular formula: C14H14N4O3. Mole weight: 286.29. | |
| CC-17368 | CC-17368 is a hydroxyisoindole derivative and metabolite of pomalidomide that has potential activity in anticancer study like multiple myeloma. Synonyms: CC 17368; CC17368; Pomalidomide metabolite M17; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-. Grades: 98%. CAS No. 1547162-41-3. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-17369 | CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma. Synonyms: CC-17369; CC 17369; CC17369; Pomalidomide metabolite M16; M16(CC-17369); SCHEMBL15439588; 4-amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindole-1,3-dione. Grades: 98%. CAS No. 1547162-46-8. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-223 | CC-223, a mTOR kinase inhibitor, has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. It is still under Phase I/II clinical trial by Celgene Corporation. IC50: 16 nM. Uses: Cc-223 is a mtor kinase inhibitor that has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. Synonyms: CC-223; CC 223; CC223; UNII-I8RA3543SY; I8RA3543SY; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyraz. Grades: 98%. CAS No. 1228013-30-6. Molecular formula: C21H27N5O3. Mole weight: 397.47. | |
| CC260 | CC260 is a selective PI5P4K? and PI5P4K? inhibitor with Kis of 40 nM and 30 nM, respectively. CC260 does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. CC260 can be used for cell energy metabolism, diabetes and cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2411088-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139188. | |
| CC2BP | CC2BP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(4-(9H-3,9'-bicarbazol-9-yl)phenyl)methanone. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1233215-35-4. Molecular formula: C61H38N4O. Mole weight: 842.98 g/mol. Product ID: ACM1233215354. Alfa Chemistry ISO 9001:2015 Certified. Categories: CCBP2. | |
| CC-3052 | CC-3052, a thalidomide analogue, reduces persistent activation of the TNF-α system in HIV without markedly impairing neutrophil viability. Synonyms: CC-3052; CC 3052; CC3052; methyl (2R)-2-(3,4-dimethoxyphenyl)-3-(3-oxo-1H-isoindol-2-yl)propanoate. Grades: >98%. CAS No. 216884-02-5. Molecular formula: C20H21NO5. Mole weight: 355.38. | |
| CC-3060 | CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 444288-86-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153698. | |
| CC4 | CC4 is a selective α6β2 and α4β2 nAChR partial agonist (Ki = 12 and 26nM for rat α6β2 and α4β2 receptors, respectively). CC4 stimulates dopamine release from striatal slices in vitro, and attenuates nicotine-induced self-administration and conditional place preference in vivo. Synonyms: CC4; CC 4; CC-4; Alternine; Ethylenedi-cytisine; (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one. Grades: ≥98% by HPLC. CAS No. 492-02-4. Molecular formula: C24H30N4O2. Mole weight: 406.52. | |
| CC4 | CC4. Group: Biochemicals. Grades: Purified. CAS No. 492-02-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CC4 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CC-401 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. The activation of JNK signaling is indentified in many immune-mediated kidney disease models. Thus, as the JNK inhibitor, CC-401 is found to be effective in these renal injury models. Synonyms: CC-401; CC 401; CC401. Grades: >98%. CAS No. 395104-30-0. Molecular formula: C22H24N6O. Mole weight: 388.47. | |
| CC 401 dihydrochloride | CC 401 dihydrochloride is a potent JNK inhibitor (Ki = 25-50 nM). CC 401 competitively binds to ATP-binding site of phosphorylated JNK to inhibit JNK. Uses: Hepatoprotective. Synonyms: CC-401 dihydrochloride; CC 401 dihydrochloride; CC401 dihydrochloride; 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-96-6. Molecular formula: C22H24N6O.2HCl. Mole weight: 461.39. | |
| CC-401 dihydrochloride | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CC-401 hydrochloride | ATP-competitive, selective JNK inhibitor. Decreases c-Jun transcription activity and proliferation. Decreases cytochrome c release and caspase 3 activation. Shows anti-ischemic, anti-inflammatory and antiapoptotic effects in vivo. Synonyms: CC 401 hydrochloride; CC401 hydrochloride; CC401 HCl. Grades: >98%. CAS No. 1438391-30-0. Molecular formula: C22H25ClN6O. Mole weight: 424.93. | |
| CC-401 hydrochloride | CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC401 HCl. CAS No. 1438391-30-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13022. | |
| CC-618 | CC-618 has been found to be a PPARβ/δ antagonist that could be used to study the potential biological activity of Cys249 at some extent. IC50: 10 μM. Synonyms: 5-Thiazolecarboxamide, 4-methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-; 4-Methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-5-thiazolecarboxamide; CC 618; CC618; 4-Methyl-2-(4-(trifluoromethyl)phenyl)-N-(2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)ethyl)thiazole-5-carboxamide. Grades: 98%. CAS No. 1680204-90-3. Molecular formula: C20H15F6N3O3S2. Mole weight: 523.47. | |
| CC-671 | CC-671 is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor with IC50s of 5 and 3 nM, which is used for the treatment of triple negative breast cancer initiated from a phenotypic screen. It is selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 μM, but does inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively). Synonyms: CC671; CC 671. Grades: ≥95%. CAS No. 1618658-88-0. Molecular formula: C28H28N6O4. Mole weight: 512.6. | |
| CC-671 | CC-671 is a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor with IC50s of 0.005 and 0.006 ?M for TTK and CLK2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1618658-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108709. | |
| CC-885 | CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation. Uses: Scientific research. Group: Signaling pathways. CAS No. 1010100-07-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101488. | |
| CC-885 | CC-885 is a cereblon (CRBN) modulator with an anti-tumour activity mediated through the cereblon-dependent ubiquitination and degradation of the translation termination factor GSPT1. CC-885 potently suppresses the proliferation of human acute myeloid leukaemia (AML) tumour cell lines. Uses: Antitumor agent. Synonyms: CC 885; CC885; N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea. Grades: 99%. CAS No. 1010100-07-8. Molecular formula: C22H21ClN4O4. Mole weight: 440.88. | |
| CC-90001 | CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK). CC-90001 shows 12.9-fold selectivity for JNK1 over JNK2 in a cell-based model. CC-90001 can be used for the research of idiopathic pulmonary fibrosis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1403859-14-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138304. | |
| CC-90002 | CC-90002 is a humanized anti-CD47 monoclonal antibody. CC-90002 binds to CD47 and inhibits CD47-SIRPα interaction. CC-90002 has been used in the research of acute myeloid leukemia. Synonyms: CC 90002; CC90002. CAS No. 2085844-54-6. | |
| CC-90002 | CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar K d value. CC-90002 can be used for the research of hematologic malignancies and solid tumors [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2085844-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99172. | |
| CC-90003 | Extracellular-signal regulated kinases (ERKs) are a specific subtype of MAPK that have been extensively linked to regulation of synaptic plasticity and memory formation in many systems. CC-90003 is an irreversible and selective inhibitor of ERK1/2 with IC50s in the 10-20 nM range, which shows good kinase selectivity and antitumor activity in a 258-kinase biochemical assay. Synonyms: CC90003; CC 90003. Grades: ≥98%. CAS No. 1621999-82-3. Molecular formula: C22H21F3N6O2. Mole weight: 458.44. | |
| CC-90003 | CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621999-82-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112570. | |
| CC-90005 | CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-? (PKC-?), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-? over PKC-? (IC50=4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799574-70-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132304. | |
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