A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CbBPCb. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3'-Di(9H-pyrido[2,3-b]-indol-9-yl)biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1469997-91-8. Molecular formula: C34H22N4. Mole weight: 486.57 g/mol. Product ID: ACM1469997918. Alfa Chemistry ISO 9001:2015 Certified.
CBBPE
CBBPE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9'-(Oxybis([1,1'-biphenyl]-4',3-diyl))bis(9H-carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1470161-29-5. Molecular formula: C48H32N2O. Mole weight: 652.78 g/mol. Product ID: ACM1470161295. Alfa Chemistry ISO 9001:2015 Certified. Categories: CB Peñas Huesca.
CBD-1
CBD-1 is isolated from Canis lupus. It has antibacterial and antifungal activity.
The CBF? Activator, Kartogenin modulates the biological activity of CBF?. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
CBFβ Inhibitor
Core binding factors (CBFs) are heterodimeric transcription factors containing a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBF&beta. CBFβ Inhibitor cellular studies indicate a good correlation between the inhibitor's antiproliferative activity and the Runx1 expression level in the target cells. Synonyms: Core Binding Factor-β Inhibitor; 2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-; 5-Ethyl-4-(4-methoxyphenyl)-2-thiazolamine; Sc 221405; 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine. Grades: ≥98%. CAS No. 493028-20-9. Molecular formula: C12H14N2OS. Mole weight: 234.32.
A cell-permeable benzodiazepine that suppresses CBFalpha/Runx1-CBFbeta transactivation activity (25uM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex. Shown to inhibit oncogenic fusion CBFB-MYH11-, TEL-RUNX1-, and RUNX1-ETO-, dependent leukemia cells proliferation (IC50 = 1.1 to 21.7uM) in vitro and more effectively reduce peripheral blood c-kit+ population (300mg/kg/d via animal feed) than Cytarabine in a murine Cbfb-MYH11 leukemia model in vivo. Comparing to CBFbeta-Runx1 Inhibitor I, Ro5-3335 modulates the Runx1-CBFbeta heterodimer formation without completely disrupting the subunits interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CBHA
Histone deacetylase (HDAC) inhibitors hyperacetylate histones and increase transcriptional activity in selected genes. CBHA is a cell-permeable second generation hybrid polar agent that acts as a HDAC inhibitor. It exhibits ID50 values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively. CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture. Uses: Histone deacetylase inhibitors. Synonyms: Histone Deacetylase Inhibitor II; m-Carboxycinnamic acid bis-hydroxamide. Grades: ≥98%. CAS No. 174664-65-4. Molecular formula: C10H10N2O4. Mole weight: 222.2.
Cbi-bb zero/001606
Cbi-bb zero/001606. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBI-BB ZERO/001606;TIMTEC-BB SBB001518;4,6-DIMETHYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE-2-SULPHONYL CHLORIDE;5,7-DIMETHYL-1,2,4-TRIAZOLO [1,5A] PYRIMIDINE SULPHONYL CHLORIDE. Product Category: Heterocyclic Organic Compound. CAS No. 98169-74-5. Molecular formula: C7H7ClN4O2S. Mole weight: 246.67. Product ID: ACM98169745. Alfa Chemistry ISO 9001:2015 Certified.
Cbi-bb zero/006283
Cbi-bb zero/006283. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 9071636;CBI-BB ZERO/006283;2-HYDROXY-3-(2-METHYLPHENOXY)PROPANOIC ACID;PROPANOIC ACID, 2-HYDROXY-3-(2-METHYLPHENOXY)-;TIMTEC-BB SBB014000. Product Category: Heterocyclic Organic Compound. CAS No. 26114-38-5. Molecular formula: C10H12O4. Mole weight: 196.2. Product ID: ACM26114385. Alfa Chemistry ISO 9001:2015 Certified.
CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF- B and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Curaxin 137; CBL-C137. CAS No. 1197996-80-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18935.
CBL0137
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM. It also inhibits histone chaperone FACT (facilitates chromatin transcription) and MYC signal. Synonyms: CBL0137; CBL-0137; CBL 0137; CBLC137; CBLC-137; CBLC 137; Curaxin 137; 1,1'-(9-(2-(Isopropylamino)ethyl)-9H-carbazole-3,6-diyl)diethanone; 1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone. CAS No. 1197996-80-7. Molecular formula: C21H24N2O2. Mole weight: 336.435.
CBL0137 hydrochloride
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death. Synonyms: CBLC137; CBL-0137; Curaxin 137. Grades: ≥98%. CAS No. 1197397-89-9. Molecular formula: C21H24N2O2·HCl. Mole weight: 372.9.
CBL0137 hydrochloride
CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC 50 s of 0.37 and 0.47 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Curaxin-137 hydrochloride; CBL-C137 hydrochloride. CAS No. 1197397-89-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18935A.
Malonyl-CoA decarboxylase (MCD) is found from bacteria to humans, which has important roles in regulating fatty acid metabolism and food intake. CBM 301940 is a potent malonyl-CoA decarboxylase (MCD) inhibitor with IC50 of 23 nM. It suppresses malonyl-CoA degradation and fatty acid oxidation in isolated rat hearts, leading to secondary increase in glucose oxidation. Synonyms: (2S,3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-4-(2-oxoethyl)-2H-pyran-5-carboxylic acid, methyl ester; CBM301940; CBM-301940. Grades: ≥98%. CAS No. 902146-11-6. Molecular formula: C15H20F6N2O5. Mole weight: 422.32.
C(Boc) Acetic acid
A nucleobase for PNA synthesis. Synonyms: 2-Oxo-4-(tert-butoxycarbonylamino)-1,2-dihydropyrimidine-1-acetic acid; 2-(4-((Tert-Butoxycarbonyl)Amino)-2-Oxopyrimidin-1(2H)-yl)Acetic acid. Grades: 98%. CAS No. 172405-16-2. Molecular formula: C11H15N3O5. Mole weight: 269.25.
CBP
CBP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4'-Bis(carbazol-9-yl)biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 58328-31-7. Molecular formula: C36H24N2. Mole weight: 484.59 g/mol. Purity: 95%+. IUPACName: 9-[4-(4-carbazol-9-ylphenyl)phenyl]carbazole. Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC=C(C=C4)C5=CC=C(C=C5)N6C7=CC=CC=C7C8=CC=CC=C86. Density: 1.19 g/ml. Product ID: ACM58328317. Alfa Chemistry ISO 9001:2015 Certified.
CBP (1319-1710), GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
CBP501
CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-specific phosphatase Cdc25C (cell division checkpoint 25 C); disruption of Cdc25C activity results in the inhibition of Cdc25C dephosphorylation of the mitotic cyclin-dependent kinase complex Cdc2/cyclin B, preventing entry into the mitotic phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. Synonyms: CBP-501; CBP 501; H-D-Bpa-D-Ser-D-Trp-D-Ser-D-Phe(F5)-D-Cha-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-OH. CAS No. 565434-85-7. Molecular formula: C86H122F5N29O17. Mole weight: 1929.06.
CBP501 Affinity Peptide
CBP501 Affinity Peptide exhibits similarity to part of the human 14-3-3e αC helix, suggesting that CBP501 may bind to this region. Synonyms: H-Asn-Ser-Asp-Cys-Ile-Ile-Ser-Arg-Lys-Ile-Glu-Gln-Lys-Glu-OH; L-Glutamic acid, L-asparaginyl-L-seryl-L-α-aspartyl-L-cysteinyl-L-isoleucyl-L-isoleucyl-L-seryl-L-arginyl-L-lysyl-L-isoleucyl-L-α-glutamyl-L-glutaminyl-L-lysyl-. Grades: ≥95%. CAS No. 1351804-17-5. Molecular formula: C68H119N21O25S. Mole weight: 1662.89.
CBP-93872
CBP-93872 is a G2 checkpoint inhibitor. CBP-93872 specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint through inhibiting maintenance. CBP-93872 is an inhibitor of maintenance of the DSB-specific G2 checkpoint and thus might be a strong candidate as the basis for a drug that specifically sensitizes p53-mutated cancer cells to DSB-inducing DNA damage therapy. Synonyms: CBP 93872; CBP93872; 1-amino-3-((2-bromo-4-methylphenyl)amino)propan-2-ol. Grades: 98%. CAS No. 67427-51-4. Molecular formula: C10H15BrN2O. Mole weight: 259.14.
CBP-aminomethylenevancomycin
CBP-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP aminomethylenevancomycin.
CBP-C1-aminomethylenevancomycin
CBP-C1-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP C1 aminomethylenevancomycin.
CBP-iminomethylenevancomycin
CBP-iminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP iminomethylenevancomycin.
CBP/p300-IN-19 hydrochloride
CBP/p300-IN-19 hydrochloride is a potent and selective p300/CBP HAT inhibitor with IC 50 s of 1.4, 2.2, >100, >100 μM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively. CBP/p300-IN-19 hydrochloride shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2592638-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146277A.
CBP-V
CBP-V. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9'-([1,1'-Biphenyl]-4,4'-diyl)bis(3-ethenyl-9H-carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 908147-48-8. Molecular formula: C40H28N2. Mole weight: 536.66 g/mol. Product ID: ACM908147488. Alfa Chemistry ISO 9001:2015 Certified. Categories: CBPV.
CBR 5884
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases. Uses: 3-phosphoglycerate dehydrogenase (phgdh) inhibitor. Synonyms: CBR-5884; CBR 5884; CBR5884. Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate. Grades: ≥98%. CAS No. 681159-27-3. Molecular formula: C14H12N2O4S2. Mole weight: 336.39.
CBS1117 is an effective inhibitor of influenza A virus entry, which can inhibit influenza virus hemagglutinin. Synonyms: 2,6-Dichloro-N-[1-(Propan-2-Yl)Piperidin-4-Yl]Benzamide. Grades: 98%. CAS No. 959245-08-0. Molecular formula: C15H20Cl2N2O. Mole weight: 315.2.
CBS9106 (BMS566419)
Cas No. 1076235-04-5.
CBS, N-Cyclohexyl -2-benzothiazolesulfenami de
CBS, N-Cyclohexyl -2-benzothiazolesulfenami de . Group: Biochemicals. Grades: Highly Purified. CAS No. 95-33-0. Pack Sizes: 250g, 500g. US Biological Life Sciences.
Worldwide
Cbz-1-amino-1-cyclooctanecarboxylic acid
Cbz-1-amino-1-cyclooctanecarboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-1-AMINO-1-CYCLOOCTANECARBOXYLIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 175407-63-3. Molecular formula: C17H23NO4. Mole weight: 305.37. Purity: 0.96. IUPACName: 1-(phenylmethoxycarbonylamino)cyclooctane-1-carboxylate. Canonical SMILES: C1CCCC(CCC1)(C(=O)O)NC(=O)OCC2=CC=CC=C2. Product ID: ACM175407633. Alfa Chemistry ISO 9001:2015 Certified.
CBZ-8-amino-3,6-dioxaoctanoic acid
CBZ-8-amino-3,6-dioxaoctanoic acid. Group: Polymers. CAS No. 16545-06-8.
CBZ-9-amino-4,7-dioxanonanoic acid
CBZ-9-amino-4,7-dioxanonanoic acid. Group: Polymers. CAS No. 462100-05-6.
Cbz-allo-thr(tbu)-oh·dcha
Cbz-allo-thr(tbu)-oh·dcha. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 198828-94-3, Z-Allo-thr(tbu)-oh dcha, MolPort-020-004-628, AKOS015911533, AK105242, B-7696, I14-37239, Dicyclohexylamine (2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)butanoate. Product Category: Heterocyclic Organic Compound. CAS No. 198828-94-3. Molecular formula: C28H46N2O5. Mole weight: 490.68. Purity: 0.96. IUPACName: N-cyclohexylcyclohexanamine;(2S,3S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoic acid. Product ID: ACM198828943. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-beta-amino-L-alanine tert-butyl ester hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS022181690, AK-62642, (S)-tert-Butyl 3-amino-2-(((benzyloxy)carbonyl)amino)propanoate hydrochloride, 174796-88-4. Product Category: Heterocyclic Organic Compound. CAS No. 174796-88-4. Molecular formula: C15H23ClN2O4. Mole weight: 330.807120 [g/mol]. Purity: 0.96. IUPACName: tert-butyl (2S)-3-amino-2-(phenylmethoxycarbonylamino)propanoate;hydrochloride. Product ID: ACM174796884. Alfa Chemistry ISO 9001:2015 Certified. Categories: H-L-Dap(Z)-OtBu HCl.
Cbz-Cyclohexyl-L-glycine
A gylicine derivative used in the preparation of peptides as inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4A protease. Group: Biochemicals. Alternative Names: (α S) -α - [ [ (Phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid; (S) -α - [ [ (phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 69901-75-3. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Cbz-D-Aze-OH
Synonyms: Z-D-Azetidine-2-Carboxylic acid; Cbz D Aze OH. CAS No. 25654-51-7. Molecular formula: C12H13NO4. Mole weight: 235.24.
Cbz-D-(-)-Phenylglycine
Cbz-D-(-)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 17609-52-8. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences.
Cbz-glycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1138-80-3. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Cbz-glycine hydrazide
Cbz-glycine hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 5680-83-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Cbz-glycine methyl ester
Cbz-glycine methyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 1212-53-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Cbz-L-Aspartic 4-tert-butyl ester
Cbz-L-Aspartic 4-tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 5545-52-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C16H21NO6. US Biological Life Sciences.
Worldwide
Cbz-L-β-homoAsp(otBu)-OH
Cas No. 83436-45-7. Molecular formula: C17H23NO6. Mole weight: 337.4.
Cbz-L-glutamine
Cbz-L-glutamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2650-64-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences.
Worldwide
Cbz-L-hydroxyproline
Cbz-L-hydroxyproline. Group: Biochemicals. Grades: Highly Purified. CAS No. 13504-85-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Cbz-L-Isoleucine dicyclohexylamine salt
Cbz-L-Isoleucine dicyclohexylamine salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 26699-00-3. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C26H42N2O4. US Biological Life Sciences.
Worldwide
Cbz-L-(+)-Phenylglycine
Cbz-L-(+)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53990-33-3. Pack Sizes: 50g, 100g. US Biological Life Sciences.
Worldwide
Cbz-L-pyroglutamic acid
Cbz-L-pyroglutamic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 32159-21-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H13NO5. US Biological Life Sciences.
Worldwide
Cbz-L-tert-Leucine
Leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors. Group: Biochemicals. Alternative Names: 3-Methyl-N-[ (phenylmethoxy) carbonyl]-L-valine; N-Carbobenzoxy-(S)-tert-leucine; 2S-Benzyloxycarbonylamino-3,3-dimethylbutyric Acid; Z-L-tert-Leucine; Benzyloxycarbonyl-L-tert-leucine; N-(Benzyloxycarbonyl)-L-tert-butylglycine; N-Benzyloxycarbonyl-L-tert-leucine; N-Benzyloxycarbonyl-tert-leucine. Grades: Highly Purified. CAS No. 62965-10-0. Pack Sizes: 2.5g. US Biological Life Sciences.
Cbz-N-amido-PEG6-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 1334177-80-8. Molecular formula: C23H37NO10. Mole weight: 487.24. Purity: 95%+. Product ID: ACM1334177808. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-neuraminic acid
Cbz-neuraminic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-NEURAMINIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 17367-66-7. Molecular formula: C17H23NO10. Mole weight: 401.37. Purity: 0.96. Product ID: ACM17367667. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-O-methyl-L-ser
Cbz-O-methyl-L-ser. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-L-SERINE(METHYL ETHER);CBZ-O-METHYL-L-SER;CBZ-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 134807-65-1. Molecular formula: C12H15NO5. Mole weight: 253.25. Product ID: ACM134807651. Alfa Chemistry ISO 9001:2015 Certified.
CC0651
CC0651, a Cdc34 ubiquitin-conjugating enzyme allosteric inhibitor, has been found to restrain the cell proliferation at some extent in cancer cell lines PC-3. IC50: 1.72 uM (inhibited the ubiquitination of p27 Kip1). Uses: Cc0651 is a cdc34 ubiquitin-conjugating enzyme allosteric inhibitor that has been found to restrain the cell proliferation at some extent in cancer cell lines pc-3. ic50: 1.72 um (inhibited the ubiquitination of p27 kip1). Synonyms: CC0651;CC 0651; CC-0651; (2R, 3S, 4S)-5-[4-(3, 5-dichlorophenyl)phenyl]-2, 3-dihydroxy-4-[(2-methoxyacetyl)amino]pentanoicacid; CC0651; 1319207-44-7; 4, 5-Dideoxy-5-(3', 5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-ArabinonicAcid; U94; SCHEMBL14884531. Grades: 95%. CAS No. 1319207-44-7. Molecular formula: C20H21Cl2NO6. Mole weight: 442.29.
CC-1065
CC-1065 is originally isolated from Streptomyces zelensis and its bioactivity was very strong. CC-1065 is against gram-positive bacteria with the MIC=1-10 ng/mL, against most gram-negative bacterial and fungi with the MIC of 1 μg/mL. Synonyms: Antibiotic CC 1065; NSC298223; CCRIS 2174. CAS No. 69866-21-3. Molecular formula: C37H33N7O8. Mole weight: 703.70.
CC-1088
CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). Uses: Cytokine inhibitor. Synonyms: CC1088; CC 1088; CC-1088. 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamide. Grades: ≥98%. CAS No. 467421-06-3. Molecular formula: C17H14N2O3. Mole weight: 294.31.
CC-115
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CC115 ; CC-115; CC 115. Product Category: Inhibitors. Appearance: Red solid powder. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.14. Purity: >98%. IUPACName: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one. Canonical SMILES: O=C1CNC2=NC=C(C3=CC=C(C4=NC=NN4)N=C3C)N=C2N1CC. Product ID: ACM1228013157. Alfa Chemistry ISO 9001:2015 Certified.
CC-115
CC-115, a DNA-PK and mTOR inhibitor, has been found to have probable anticarcinoma effect. IC50:13 nM and 21 nM for DNA-PK and mTOR respectively. Uses: Cc-115 is a dna-pk and mtor inhibitor and has been found to have probable anticarcinoma effect. Synonyms: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one; CC115 ; CC-115; CC 115. Grades: 98%. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.35.
CC-115 hydrochloride
The hydrochloride salt form of CC-115 which is a mTOR / DNA-PK inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. IC50: 21 nM and 13 nM for mTOR and DNA-PK respectively. Uses: The hydrochloride salt form of cc-115 which is a mtor / dna-pk inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. Synonyms: CC115 hydrochloride ; CC-115 hydrochloride; CC 115 hydrochloride. Grades: 98%. CAS No. 1300118-55-1. Molecular formula: C16H17ClN8O. Mole weight: 372.81.
CC-12074
A Metabolite of Pomalidomide. Uses: Pomalidomide metabolite. Synonyms: CC-12074; CC12074; CC 12074; Pomalidomide metabolite M19; UNII-A480CC1Z8I; SCHEMBL3742152.4-amino-2-(5-hydroxy-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Grades: ≥98%. CAS No. 460741-57-5. Molecular formula: C13H11N3O5. Mole weight: 289.24.
CC122
CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial. Uses: Cc122 has antitumor and immunomodulatory activity. it is used for the treatment of chronic lymphocytic leukemia. Synonyms: 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione;CC-122; CC122; CC 122. Grades: >98 %. CAS No. 1015474-32-4. Molecular formula: C14H14N4O3. Mole weight: 286.29.