A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CBR-470-1, a non-covalent Nrf2 activator, is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). It protects SH-SY5Y neuronal cells from MPP+ induced cytotoxicity by activating the Keap1-Nrf2 cascade. Synonyms: 3-Thiophenamine, 4-[(4-chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-, 1,1-dioxide, (3R,4S)-rel-; (3S,4R)-4-[(4-Chlorophenyl)sulfonyl]-N-isobutyltetrahydro-3-thiophenamine 1,1-dioxide; (3S,4R)-4-[(4-chlorophenyl)sulfonyl]-3-[(2-methylpropyl)amino]thiolane-1,1-dione. Grade: ≥98%. CAS No. 2416095-06-0. Molecular formula: C14H20ClNO4S2. Mole weight: 365.90.
CBR-470-1
CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416095-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134205A.
CBR-470-2
CBR-470-2, an analogue of glycine substitution, activates NRF2 signaling and can be used to study modulation glycolysis. Synonyms: N-{(3S,4R)-4-[(3,4-Dichlorophenyl)sulfonyl]-1,1-dioxidotetrahydro-3-thiophenyl}glycine; Glycine, N-[(3R,4S)-4-[(3,4-dichlorophenyl)sulfonyl]tetrahydro-1,1-dioxido-3-thienyl]-, rel-. Grade: ≥95%. CAS No. 2416095-00-4. Molecular formula: C12H13Cl2NO6S2. Mole weight: 402.27.
CBR 5884
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases. Uses: 3-phosphoglycerate dehydrogenase (phgdh) inhibitor. Synonyms: CBR-5884; CBR 5884; CBR5884. Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate. Grade: ≥98%. CAS No. 681159-27-3. Molecular formula: C14H12N2O4S2. Mole weight: 336.39.
CBR-5884
CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 ?M. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 681159-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100012.
CBS1117 is an effective inhibitor of influenza A virus entry, which can inhibit influenza virus hemagglutinin. Synonyms: 2,6-Dichloro-N-[1-(Propan-2-Yl)Piperidin-4-Yl]Benzamide. Grade: 98%. CAS No. 959245-08-0. Molecular formula: C15H20Cl2N2O. Mole weight: 315.2.
CBS9106
CBS9106, also known as BMS-566419, is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity. CRM1 plays an important role in the nuclear export of cargo proteins bearing nuclear exporting signal sequences. CBS9106 inhibits CRM1-dependent nuclear export, causing arrest of the cell cycle and inducing apoptosis in a time- and dose-dependent manner for a broad spectrum of cancer cells, including multiple myeloma cells. CBS9106 reduces CRM1 protein levels significantly without affecting CRM1 mRNA expression. Oral administration of CBS9106 significantly suppresses tumor growth and prolongs survival in mice bearing tumor xenograft without a significant loss in body weight. A reduced level of CRM1 protein is also observed in tumor xenografts isolated from mice treated with CBS9106. Taken together, these results indicate that CBS9106 is a novel reversible CRM1 inhibitor and a promising clinical candidate. Synonyms: SL-801; SL801; SL 801; CBS-9106; CBS 9106; BMS-566419; BMS566419; BMS 566419; 1H-Pyrrole-2,5-dione, 1-[[6-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-[(3,3-dimethylbutoxy)methyl]-4-methyl-. Grade: 98%. CAS No. 1076235-04-5. Molecular formula: C18H21ClF3N3O3. Mole weight: 419.83.
CBS, N-Cyclohexyl -2-benzothiazolesulfenami de
CBS, N-Cyclohexyl -2-benzothiazolesulfenami de . Group: Biochemicals. Grades: Highly Purified. CAS No. 95-33-0. Pack Sizes: 250g, 500g. US Biological Life Sciences.
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CBT-161
CBT-161 is an ADC that STI-A0602, the monoclonal antibody targeting c-Met, links tubulin inhibitors or DNA damaging agents via C-lock. Preclinical study showed that CBT-161 significantly inhibited tumor growth. Uses: Antitumor drug. Synonyms: Anti-cMET ADC.
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is an effective and selective short-acting peptide V2 receptor (V2R) agonist. Synonyms: D-Argininamide, 4-chloro-N-(4-mercapto-1-oxobutyl)-L-phenylalanyl-3-(2-thienyl)-L-alanyl-L-valyl-L-asparaginyl-L-cysteinyl-L-prolyl-N,N-diethyl-, cyclic (1→5)-thioether. CAS No. 1647119-71-8. Molecular formula: C47H69ClN12O9S2. Mole weight: 1045.71.
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 is an effective and selective short-acting peptide V2 receptor (V2R) agonist. Synonyms: Velmupressin; L-Prolinamide, 4-chloro-N-(4-mercapto-1-oxobutyl)-L-phenylalanyl-3-(2-thienyl)-L-alanyl-L-valyl-L-asparaginyl-L-cysteinyl-N-(4-((aminoiminomethyl)amino)butyl)-, cyclic (1->5)-thioether. Grade: ≥98%. CAS No. 1647119-61-6. Molecular formula: C42H60ClN11O8S2. Mole weight: 946.58.
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate
It is a potent, selective and short-acting peptide V2 receptor (V2R) agonist. Synonyms: 1-{[(3R,6S,9S,12S,15S)-6-(2-Amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(2-thienylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosan-3-yl]carbonyl}-N-(4-carbamimidamidobutyl)-L-prolinamide acetate (1:1). Grade: ≥98%. CAS No. 1647120-04-4. Molecular formula: C44H64ClN11O10S2. Mole weight: 1006.63.
Cbz-1-amino-1-cyclooctanecarboxylic acid
Cbz-1-amino-1-cyclooctanecarboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-1-AMINO-1-CYCLOOCTANECARBOXYLIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 175407-63-3. Molecular formula: C17H23NO4. Mole weight: 305.37. Purity: 0.96. IUPACName: 1-(phenylmethoxycarbonylamino)cyclooctane-1-carboxylate. Canonical SMILES: C1CCCC(CCC1)(C(=O)O)NC(=O)OCC2=CC=CC=C2. Product ID: ACM175407633. Alfa Chemistry ISO 9001:2015 Certified.
CBZ-8-amino-3,6-dioxaoctanoic acid
CBZ-8-amino-3,6-dioxaoctanoic acid. Group: Polymers. CAS No. 16545-06-8.
CBZ-9-amino-4,7-dioxanonanoic acid
CBZ-9-amino-4,7-dioxanonanoic acid. Group: Polymers. CAS No. 462100-05-6.
Cbz-Aib-Leu-OMe
Cbz-Aib-Leu-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the α-aminoisobutyric acid (Aib) residue, preventing unwanted reactions during synthesis. Aib is a non-natural amino acid that induces helical structures in peptides due to its steric properties. Leu (Leucine) is the second amino acid in the sequence, known for its hydrophobic character, contributing to the overall structure and stability of the peptide. The OMe (methyl ester) group at the C-terminus indicates that the carboxyl group is esterified, which can be useful in strategies where further peptide extension or specific cleavage is required. This compound is employed to introduce both structural constraints and hydrophobic properties into peptides, enhancing their desired functional characteristics. Synonyms: N-Benzoxycarbonyl-alpha-methyl-alanyl-L-leucine methyl ester; Methyl (2-(((benzyloxy)carbonyl)amino)-2-methylpropanoyl)-L-leucinate; Z-Aib-Leu-OMe; L-Leucine, 2-methyl-N-[(phenylmethoxy)carbonyl]alanyl-, methyl ester; 2-Methyl-N-[(phenylmethoxy)carbonyl]alanyl-L-leucine methyl ester. Grade: ≥95%. CAS No. 866919-63-3. Molecular formula: C19H28N2O5. Mole weight: 364.44.
Cbz-allo-thr(tbu)-oh·dcha
Cbz-allo-thr(tbu)-oh·dcha. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 198828-94-3, Z-Allo-thr(tbu)-oh dcha, MolPort-020-004-628, AKOS015911533, AK105242, B-7696, I14-37239, Dicyclohexylamine (2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)butanoate. Product Category: Heterocyclic Organic Compound. CAS No. 198828-94-3. Molecular formula: C28H46N2O5. Mole weight: 490.68. Purity: 0.96. IUPACName: N-cyclohexylcyclohexanamine;(2S,3S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoic acid. Product ID: ACM198828943. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro-OH
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro-OH is a protected hexapeptide used in peptide synthesis. It consists of aspartic acid (Asp), phenylalanine (Phe), glutamic acid (Glu), isoleucine (Ile), and proline (Pro). The Cbz (Carbobenzyloxy) group protects the N-terminus of aspartic acid, while the OtBu (tert-butyl) groups protect the hydroxyl groups of the glutamic acid residues. The remaining amino acids are in their free forms, with the C-terminus of the proline residue indicated by -OH, allowing for further coupling or modifications. This hexapeptide is designed for controlled reactivity and stability during peptide synthesis. Synonyms: Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro; ((S)-2-((S)-2-((S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanamido)-3-phenylpropanamido)-5-(tert-butoxy)-5-oxopentanamido)-5-(tert-butoxy)-5-oxopentanoyl)-L-isoleucyl-L-proline; Cbz-Asp(tBu)-Phe-Glu(tBu)-Glu(tBu)-Ile-Pro-OH. Grade: ≥90%. Molecular formula: C54H78N6O15. Mole weight: 1051.25.
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OH
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from reacting during synthesis. Both the aspartic acid and glutamic acid (Glu) residues have their side chain carboxyl groups protected by OtBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is required. Phe (Phenylalanine) is the central amino acid in the sequence, contributing aromatic character. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is used to introduce aspartic acid, phenylalanine, and glutamic acid into peptides with specific protections to control the reactivity and maintain the integrity of functional groups during synthesis. Synonyms: DFE; ((Benzyloxy)carbonyl)-O-(tert-butyl)-L-aspartyl-L-phenylalanyl-O-(tert-butyl)-L-glutamic acid; Z-Asp(OtBu)-Phe-Glu(OtBu)-OH. Grade: ≥95%. Molecular formula: C34H45N3O10. Mole weight: 655.75.
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OMe
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from reacting during the synthesis process. Both the aspartic acid and glutamic acid (Glu) residues have their side chain carboxyl groups protected by OtBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is required. Phe (Phenylalanine), the central amino acid in the sequence, adds hydrophobic and aromatic properties to the peptide. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the glutamic acid is esterified, which can be useful for further synthetic modifications or coupling reactions. This compound is employed to introduce aspartic acid, phenylalanine, and glutamic acid into peptides, with controlled reactivity through specific protective groups. Synonyms: DFE; 5-(tert-Butyl) 1-methyl ((S)-2-(((benzyloxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-L-phenylalanyl-L-glutamate; Z-Asp(OtBu)-Phe-Glu(OtBu)-OMe. Grade: ≥95%. Molecular formula: C35H47N3O10. Mole weight: 669.77.
Cbz-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe
Cbz-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from participating in unwanted reactions. The side chains of aspartic acid, tyrosine (Tyr), and serine (Ser) are each protected by OtBu (tert-butyl) groups, which shield their carboxyl and hydroxyl groups from reactivity until selective deprotection is desired. Tyr contributes aromatic and hydrophobic properties to the peptide, while Ser adds additional functionality. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of serine is esterified, which can facilitate further chemical modifications or reactions. This compound is used to incorporate aspartic acid, tyrosine, and serine into peptides, with specific protections to ensure controlled synthesis and reactivity of functional groups. Synonyms: DYS; Cbz-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OMe; Z-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe; Methyl (5S,8S,11S)-5-(2-(tert-butoxy)-2-oxoethyl)-8-(4-(tert-butoxy)benzyl)-11-(tert-butoxymethyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oate. Grade: ≥95%. Molecular formula: C37H53N3O10. Mole weight: 699.84.
A gylicine derivative used in the preparation of peptides as inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4A protease. Group: Biochemicals. Alternative Names: (α S) -α - [ [ (Phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid; (S) -α - [ [ (phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 69901-75-3. Pack Sizes: 5g. US Biological Life Sciences.
Cbz-Glu(OtBu)-Ile-Pro-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the glutamic acid (Glu) residue, preventing it from participating in unwanted reactions. The side chain of glutamic acid is further protected by an OtBu (tert-butyl) group, which shields the carboxyl group from reactivity until selective deprotection is required. Ile (Isoleucine), the middle amino acid in the sequence, adds hydrophobic properties, while Pro (Proline) is the third amino acid, known for inducing kinks in peptide chains due to its rigid cyclic structure. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of proline is esterified, which can be useful in controlling reactivity or further synthetic modifications. This compound is used to incorporate glutamic acid, isoleucine, and proline into peptides while maintaining precise control over the reactivity of the functional groups. Synonyms: EIP; Methyl ((S)-2-(((benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoyl)-L-isoleucyl-L-prolinate; Z-Glu(OtBu)-Ile-Pro-OMe. Grade: ≥95%. Molecular formula: C29H43N3O8. Mole weight: 561.68.
Cbz-glycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1138-80-3. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences.
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Cbz-glycine hydrazide
Cbz-glycine hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 5680-83-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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Cbz-glycine methyl ester
Cbz-glycine methyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 1212-53-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
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Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH
Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH is a protected pentapeptide used in peptide synthesis. The sequence includes glycine (Gly), proline (Pro), and two serine (Ser) residues, with the C-terminus glycine being free, denoted by -OH, allowing for further coupling or modifications. The Cbz (Carbobenzyloxy) group protects the N-terminus of the glycine residue, while the OtBu (tert-butyl) groups protect the hydroxyl groups of the serine residues, preventing unwanted reactions during synthesis. This peptide sequence is designed to be incorporated into larger peptides or proteins, with the protective groups ensuring controlled reactivity and stability throughout the synthesis process. Synonyms: GPSSG; N-(N-((Benzyloxy)carbonyl)glycyl-L-prolyl-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycine; Z-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH; Cbz-Gly-Pro-Ser(tBu)-Ser(tBu)-Gly-OH. Grade: ≥99%. Molecular formula: C31H47N5O10. Mole weight: 649.74.
Cbz-Ile-Aib-Leu-OH
Cbz-Ile-Aib-Leu-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the isoleucine (Ile) residue, preventing it from reacting during synthesis. Aib (α-aminoisobutyric acid), a non-natural amino acid known for inducing helical structures, follows isoleucine. Leu (Leucine), the final amino acid in the sequence, adds hydrophobic properties. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling or modifications. This compound is used to introduce isoleucine, Aib, and leucine into peptides while controlling the reactivity of their functional groups through selective protection. Synonyms: IXL; (2-((2S,3S)-2-(((Benzyloxy)carbonyl)amino)-3-methylpentanamido)-2-methylpropanoyl)-L-leucine; Z-Ile-Aib-Leu-OH. Grade: ≥95%. Molecular formula: C24H37N3O6. Mole weight: 463.58.
Cbz-L-Aspartic 4-tert-butyl ester
Cbz-L-Aspartic 4-tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 5545-52-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C16H21NO6. US Biological Life Sciences.
Worldwide
Cbz-L-β-homoAsp(otBu)-OH
Cbz-L-β-homoAsp(otBu)-OH. CAS No. 83436-45-7. Molecular formula: C17H23NO6. Mole weight: 337.4.
Cbz-L-glutamine
Cbz-L-glutamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2650-64-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences.
Worldwide
Cbz-L-hydroxyproline
Cbz-L-hydroxyproline. Group: Biochemicals. Grades: Highly Purified. CAS No. 13504-85-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
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Cbz-L-Isoleucine dicyclohexylamine salt
Cbz-L-Isoleucine dicyclohexylamine salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 26699-00-3. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C26H42N2O4. US Biological Life Sciences.
Worldwide
Cbz-L-(+)-Phenylglycine
Cbz-L-(+)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53990-33-3. Pack Sizes: 50g, 100g. US Biological Life Sciences.
Worldwide
Cbz-L-pyroglutamic acid
Cbz-L-pyroglutamic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 32159-21-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H13NO5. US Biological Life Sciences.
Worldwide
Cbz-L-tert-Leucine
Leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors. Group: Biochemicals. Alternative Names: 3-Methyl-N-[ (phenylmethoxy) carbonyl]-L-valine; N-Carbobenzoxy-(S)-tert-leucine; 2S-Benzyloxycarbonylamino-3,3-dimethylbutyric Acid; Z-L-tert-Leucine; Benzyloxycarbonyl-L-tert-leucine; N-(Benzyloxycarbonyl)-L-tert-butylglycine; N-Benzyloxycarbonyl-L-tert-leucine; N-Benzyloxycarbonyl-tert-leucine. Grades: Highly Purified. CAS No. 62965-10-0. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Cbz-MeGly(heptene)-OH
Cbz-MeGly(heptene)-OH is a protected amino acid derivative used in peptide synthesis. The Cbz (carbobenzyloxy) group serves as a protective group for the amino terminus, preventing unwanted reactions during synthesis. MeGly refers to N-methylglycine, a simple amino acid derivative, and (heptene) indicates the presence of a heptene moiety, likely modifying the side chain for added hydrophobicity or reactivity. This compound is useful in creating modified peptides with specific structural or functional properties. Synonyms: Z-MeGly(heptene)-OH. Grade: ≥95%. Molecular formula: C16H21NO4. Mole weight: 291.35.
Cbz-N-amido-PEG6-acid
Cbz-N-amido-PEG6-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 1334177-80-8. Molecular formula: C23H37NO10. Mole weight: 487.24. Purity: 95%+. Product ID: ACM1334177808. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-neuraminic acid
Cbz-neuraminic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-NEURAMINIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 17367-66-7. Molecular formula: C17H23NO10. Mole weight: 401.37. Purity: 0.96. Product ID: ACM17367667. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-O-methyl-L-ser. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-L-SERINE(METHYL ETHER);CBZ-O-METHYL-L-SER;CBZ-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 134807-65-1. Molecular formula: C12H15NO5. Mole weight: 253.25. Product ID: ACM134807651. Alfa Chemistry ISO 9001:2015 Certified.
Cbz-Phe-Thr(tBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the phenylalanine (Phe) residue, preventing it from participating in unwanted reactions during the synthesis. The Thr (Threonine) residue is protected at its hydroxyl side chain by a tBu (tert-butyl) group, safeguarding this functional group until selective deprotection is needed. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group is esterified, which can be useful in certain synthetic strategies to prevent reactions at the carboxyl end. This compound is used to introduce phenylalanine and threonine into peptides while maintaining control over the reactivity of the functional groups. Synonyms: Methyl N-(((benzyloxy)carbonyl)-L-phenylalanyl)-O-(tert-butyl)-L-threoninate; Z-Phe-Thr(tBu)-OMe; FT; L-Threonine, O-(1,1-dimethylethyl)-N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, methyl ester; Cbz-Phe-Thr(OtBu)-OMe. Grade: ≥95%. Molecular formula: C26H34N2O6. Mole weight: 470.57.
Cbz-Pro-Ala-NH2
Cbz-Pro-Ala-NH2 is a protected dipeptide derivative used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the proline (Pro) residue, preventing it from participating in unwanted reactions during the peptide synthesis process. Ala (Alanine) is the second amino acid in the sequence, and the -NH2 indicates a free amino group at the C-terminus of alanine, allowing for further peptide coupling or modification. This compound is used to introduce proline and alanine into peptides while controlling the reactivity of the functional groups through selective protection. Synonyms: Z-Pro-Ala-NH2; PA. Grade: ≥95%. Molecular formula: C16H21N3O4. Mole weight: 319.36.
Cbz-Pro-Pro-Ser(OtBu)-NH2
Cbz-Pro-Pro-Ser(OtBu)-NH2 is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the proline (Pro) residue, preventing it from reacting during synthesis. The Pro-Pro sequence consists of two proline residues, known for their role in introducing kinks or turns in peptide chains. The side chain hydroxyl group of the serine (Ser) residue is protected by an OtBu (tert-butyl) group to prevent unwanted reactions until deprotection. The -NH2 at the C-terminus indicates a free amine group, allowing for further modifications or coupling reactions. This peptide is used to incorporate proline and serine into peptides, with specific protections to ensure controlled synthesis and functional group reactivity. Synonyms: PPS; Benzyl (S)-2-((S)-2-(((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate; Z-Pro-Pro-Ser(OtBu)-NH2; Cbz-Pro-Pro-Ser(tBu)-NH2. Grade: ≥97%. Molecular formula: C25H36N4O6. Mole weight: 488.59.
Cbz-Pyr-Gly-Arg-MCA
Cbz-Pyr-Gly-Arg-MCA is an inhibitor of protein interactions. It binds to the peptide receptor and blocks the activation of the receptor. Synonyms: L-Argininamide, 5-oxo-1-[(phenylmethoxy)carbonyl]-L-prolylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. CAS No. 113865-89-7. Molecular formula: C31H35N7O8. Mole weight: 633.65.
Cbz-Sar-Sar-OH
Cbz-Sar-Sar-OH is a peptide building block used in peptide synthesis. It features a Cbz (Carbobenzyloxy) protective group on the N-terminus, which prevents unwanted reactions during the peptide assembly process. The core structure includes two Sar (Sarcosine) residues, a small amino acid derivative with a methyl group replacing one hydrogen, which contributes to flexibility and hydrophobic interactions. The -OH at the C-terminus denotes a free carboxyl group, allowing for coupling with other amino acids. This compound is used to introduce specific dipeptide sequences into peptides, modifying their structural and functional properties. Synonyms: N-Benzoxycarbonyl-sarcosyl-sarcosine; N-[(Benzyloxy)carbonyl]-N-methylglycyl-N-methylglycine; N-(N-((Benzyloxy)carbonyl)-N-methylglycyl)-N-methylglycine; Z-Sar-Sar-OH. Grade: ≥95%. CAS No. 62245-96-9. Molecular formula: C14H18N2O5. Mole weight: 294.30.
Cbz-Sar-Sar-Sar-Sar-OH
Cbz-Sar-Sar-Sar-Sar-OH is a protected tetrapeptide composed of four sarcosine (Sar) residues, a derivative of glycine with a methyl group on the nitrogen atom. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first sarcosine residue, while the C-terminus of the final sarcosine residue is free, indicated by -OH, allowing for further coupling or modifications. This tetrapeptide is designed to introduce a flexible, non-chiral sequence into peptide chains, often used to modify the physical properties of the resulting peptide, such as increasing solubility or altering conformation. The protective groups ensure that the synthesis proceeds in a controlled and selective manner. Synonyms: 4,7,10,13-Tetramethyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazapentadecan-15-oic acid; Z-Sar-Sar-Sar-Sar-OH; Cbz-Sar-Sar-Sar-Sar. Grade: ≥95%. Molecular formula: C20H28N4O7. Mole weight: 436.47.
Cbz-Ser(OtBu)-Asp(OtBu)-OMe
Cbz-Ser(OtBu)-Asp(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from reacting during synthesis. The hydroxyl group on serine is protected by a tBu (tert-butyl) group, which shields it until deprotection is required. The Asp (Aspartic acid) residue also has its side chain protected by a tBu group, ensuring that the side chain carboxyl group remains unreactive. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the aspartic acid is esterified, which can facilitate further reactions or modifications. This compound is utilized to incorporate serine and aspartic acid into peptides, with specific protections in place to ensure controlled synthesis and functional modifications. Synonyms: SD; 4-(tert-Butyl) 1-methyl N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl-L-aspartate; Z-Ser(OtBu)-Asp(OtBu)-OMe. Grade: ≥95%. Molecular formula: C24H36N2O8. Mole weight: 480.56.
Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH
Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH is a protected tripeptide used in peptide synthesis. The peptide consists of serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine residue, while the OtBu (tert-butyl) groups protect the hydroxyl and carboxyl side chains of the serine, aspartic acid, and tyrosine residues, preventing them from participating in unwanted side reactions during synthesis. The C-terminus of the tyrosine residue is free, indicated by -OH, allowing for further coupling or deprotection. This protected tetrapeptide is designed to be incorporated into larger peptide sequences in a controlled manner, ensuring selective reactivity and stability throughout the synthesis process. Synonyms: SDY; (5S,8S,11S)-8-(2-(tert-Butoxy)-2-oxoethyl)-11-(4-(tert-butoxy)benzyl)-5-(tert-butoxymethyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid; Z-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH; Cbz-Ser(tBu)-Asp(tBu)-Tyr(tBu)-OH. Grade: ≥95%. Molecular formula: C36H51N3O10. Mole weight: 685.82.
Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH
Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH is a protected tetrapeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first serine (Ser) residue, preventing it from participating in undesired reactions during synthesis. The side chains of the serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues are protected by OtBu (tert-butyl) groups, which shield the hydroxyl and carboxyl groups, ensuring that these functional groups remain inactive until selective deprotection. The final Ser residue has a free carboxyl group at the C-terminus, indicated by -OH, which allows for further modifications or coupling reactions. This peptide is designed to incorporate serine, aspartic acid, and tyrosine into peptide structures, with the protective groups ensuring controlled and efficient synthesis. Synonyms: SDYS; N-((S)-2-((S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-4-(tert-butoxy)-4-oxobutanamido)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serine; Z-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH; Cbz-Ser(tBu)-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OH. Grade: ≥97%. Molecular formula: C43H64N4O12. Mole weight: 829.00.
Cbz-Ser(tBu)-Ser(tBu)-Gly-OH
Cbz-Ser(tBu)-Ser(tBu)-Gly-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from participating in unwanted reactions during synthesis. The hydroxyl groups on both serine residues are protected by tBu (tert-butyl) groups, which keep these groups from reacting until they are selectively deprotected. Gly (Glycine) is the final amino acid in the sequence, and the -OH at the C-terminus indicates a free carboxyl group. This free carboxyl group allows for further peptide coupling or modification. This compound is used to incorporate serine and glycine into peptides while maintaining control over the reactivity of functional groups through specific protection strategies. Synonyms: SSG; Cbz-Ser(OtBu)-Ser(OtBu)-Gly-OH; Z-Ser(tBu)-Ser(tBu)-Gly-OH; N-(N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycine. Grade: ≥95%. Molecular formula: C24H37N3O8. Mole weight: 495.57.
Cbz-Ser(tBu)-Ser(tBu)-Gly-OMe
Cbz-Ser(tBu)-Ser(tBu)-Gly-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from reacting during synthesis. The hydroxyl groups on both serine residues are protected by tBu (tert-butyl) groups, which shield these groups from reactivity until they are selectively deprotected. Gly (Glycine), the final amino acid in the sequence, is the smallest and most flexible amino acid, with the OMe (methyl ester) at the C-terminus indicating that the carboxyl group of glycine is esterified. This esterification is useful for controlling reactivity or facilitating further modifications. This compound is used to introduce serine and glycine into peptides while maintaining precise control over functional group reactivity through selective protection. Synonyms: SSG; Methyl N-(N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycinate; Z-Ser(tBu)-Ser(tBu)-Gly-OMe; Cbz-Ser(OtBu)-Ser(OtBu)-Gly-OMe. Grade: ≥95%. Molecular formula: C25H39N3O8. Mole weight: 509.60.
Cbz-Ser(tBu)-Ser(tBu)-OH
Cbz-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group serves as a protective group for the N-terminus of the first serine residue, preventing unwanted reactions during the synthesis process. Each Ser (Serine) residue is protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring that these reactive groups remain unaltered until selective deprotection is required. The -OH at the C-terminus indicates a free carboxyl group, allowing for further coupling reactions in the peptide chain. This compound is used to incorporate serine residues into peptides, with specific protections to facilitate precise and controlled synthesis. Synonyms: N-(N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serine; N-Benzoxycarbonyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serine; SS; Cbz-Ser(OtBu)-Ser(OtBu)-OH; Z-Ser(tBu)-Ser(tBu)-OH. Grade: ≥95%. CAS No. 119439-59-7. Molecular formula: C22H34N2O7. Mole weight: 438.51.
Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OMe
Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine (Thr) residue, preventing it from participating in unwanted reactions. The hydroxyl groups on both threonine residues are protected by OtBu (tert-butyl) groups, ensuring these functional groups remain unreactive until selective deprotection is required. Phe (Phenylalanine), positioned in the middle, adds aromatic and hydrophobic properties to the peptide. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the final threonine is esterified, which can facilitate further reactions or modifications. This compound is used to incorporate threonine and phenylalanine into peptides, with controlled reactivity through selective protection, enabling precise and efficient peptide synthesis. Synonyms: TFT; Cbz-Thr(tBu)-Phe-Thr(tBu)-OMe; Z-Thr(OtBu)-Phe-Thr(OtBu)-OMe; Methyl N-N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threoninate. Grade: ≥95%. Molecular formula: C34H49N3O8. Mole weight: 627.78.
Cbz-Thr-Phe-Thr(tBu)-OMe
Cbz-Thr-Phe-Thr(tBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first threonine (Thr) residue, preventing it from participating in unwanted reactions during the synthesis process. The side chain of the second threonine residue is protected by a tBu (tert-butyl) group, shielding the hydroxyl group from reactivity until selective deprotection is needed. Phe (Phenylalanine), the middle amino acid, contributes aromatic and hydrophobic properties to the peptide sequence. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the second threonine is esterified, which is useful for controlling the reactivity and allowing further modifications or elongation of the peptide chain. This compound is employed to introduce threonine and phenylalanine into peptides, with specific protections to ensure selective and controlled synthesis. Synonyms: TFT; Methyl N-((benzyloxy)carbonyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threoninate; Z-Thr-Phe-Thr(tBu)-OMe. Grade: ≥95%. Molecular formula: C30H41N3O8. Mole weight: 571.67.
Cbz-Thr(tBu)-Phe-OH
Cbz-Thr(tBu)-Phe-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine residue, preventing reactions at this site during synthesis. The Thr (Threonine) residue is further protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring the hydroxyl group remains unreactive until deprotection is desired. Phe (Phenylalanine) is the second amino acid, contributing aromatic character to the peptide. The -OH at the C-terminus signifies a free carboxyl group, which can participate in peptide bond formation. This compound is used to introduce threonine and phenylalanine into peptides with specific protective measures for controlled and selective synthesis. Synonyms: N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine; Z-Thr(tBu)-Phe-OH; N-Benzoxycarbonyl-O3-tert-butyl-L-threonyl-L-phenylalanine; TF; L-Phenylalanine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-threonyl]-. Grade: ≥95%. CAS No. 47732-07-0. Molecular formula: C25H32N2O6. Mole weight: 456.54.
Cbz-Thr(tBu)-Phe-Thr(tBu)-OH
Cbz-Thr(tBu)-Phe-Thr(tBu)-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine (Thr) residue, preventing it from reacting during synthesis. Both threonine residues have their side chain hydroxyl groups protected by tBu (tert-butyl) groups, which shield these groups from unwanted reactions until deprotection is desired. Phe (Phenylalanine), the central amino acid in the sequence, adds aromatic and hydrophobic properties to the peptide. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is used to incorporate threonine and phenylalanine into peptides while maintaining control over the functional groups' reactivity through selective protection. Synonyms: TFT; N-N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threonine; Z-Thr(tBu)-Phe-Thr(tBu)-OH; Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OH. Grade: ≥95%. Molecular formula: C33H47N3O8. Mole weight: 613.75.
Cbz-Tyr(OtBu)-Ser(OtBu)-OMe
Cbz-Tyr(OtBu)-Ser(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the tyrosine (Tyr) residue, preventing it from reacting during synthesis. The hydroxyl group of tyrosine is protected by an OtBu (tert-butyl) group, ensuring it remains unreactive until deprotection is necessary. The Ser (Serine) residue is similarly protected at its hydroxyl group by an OtBu group. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the serine is esterified, facilitating further peptide coupling or modification. This compound is used to introduce tyrosine and serine into peptides while controlling the reactivity of their functional groups. Synonyms: Z-Tyr(OtBu)-Ser(OtBu)-OMe; Methyl N-((S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serinate; YS. Grade: ≥95%. Molecular formula: C29H40N2O7. Mole weight: 528.65.
CC0651
CC0651, a Cdc34 ubiquitin-conjugating enzyme allosteric inhibitor, has been found to restrain the cell proliferation at some extent in cancer cell lines PC-3. IC50: 1.72 uM (inhibited the ubiquitination of p27 Kip1). Uses: Cc0651 is a cdc34 ubiquitin-conjugating enzyme allosteric inhibitor that has been found to restrain the cell proliferation at some extent in cancer cell lines pc-3. ic50: 1.72 um (inhibited the ubiquitination of p27 kip1). Synonyms: CC0651; CC 0651; CC-0651; (2R,3S,4S)-5-[4-(3,5-dichlorophenyl)phenyl]-2,3-dihydroxy-4-[(2-methoxyacetyl)amino]pentanoicacid; CC0651; 1319207-44-7; 4,5-Dideoxy-5-(3',5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-ArabinonicAcid; U94; SCHEMBL14884531. Grade: 95%. CAS No. 1319207-44-7. Molecular formula: C20H21Cl2NO6. Mole weight: 442.29.