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| Product | Description | |
|---|---|---|
| Cauliflower Powder | Cauliflower Powder. |  CA, FL & NJ |
| Caulilexin A | Caulilexin A is a phytoalexin found in Brassica oleracea, which exhibits antifungal activity. Synonyms: Caulilexine A; 2-(Methyldithio)-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2-(methyldithio)-. Grades: ≥95%. CAS No. 905914-67-2. Molecular formula: C10H9NOS2. Mole weight: 223.32. |  |
| Cauloside A | Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 17184-21-3. Molecular formula: C35H56O8. Mole weight: 604.81. Purity: 0.98. IUPACName: (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Canonical SMILES: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C2C1)C)C(=O)O)C. Product ID: ACM17184213. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Caulosidec(p)(new) | Caulosidec(p)(new). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cauloside C, CID159898, 20853-58-1, 3-((2-0-beta-D-Glucopyranosyl-alpha-L-arabinopyranosyl)oxy)-23-hydroxyolean-12-en-28-oic acid. Product Category: Heterocyclic Organic Compound. CAS No. 20853-58-1. Molecular formula: C41H66O13. Mole weight: 766.96. Purity: 0.96. IUPACName: (4aS,6aR,6aS,6bR,10S,12aR,14bR)-10-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbo. Product ID: ACM20853581. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cauloside F | Cauloside F. Group: Biochemicals. Alternative Names: Cauloside G. Grades: Plant Grade. CAS No. 60451-47-0. Pack Sizes: 10mg. Molecular Formula: C60H98O27, Molecular Weight: 1251.4. US Biological Life Sciences. |  Worldwide |
| Caustic potash | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| Caustic Potash 1310-58-3 | Caustic Potash - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Caustic Potash Liquid | Caustic Potash Liquid - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Potash (wet and dry) | Caustic Potash (wet and dry) |  |
| Caustic soda | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. | |
| Caustic Soda | We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. |  California |
| Caustic Soda | Cas No. 68988-74-9. | |
| Caustic Soda 1310-73-2 | Minimum Quantity 25Kgs. Surface Coatings SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda 25%, 50%, lake & beads | 25%, 50%, lake & beads | |
| Caustic Soda 99% | Caustic Soda 99%. Market: Food Additives / Preservatives. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries. |  |
| Caustic Soda Flakes | Sodium Hydroxide or Caustic Soda, also known as lye due to its corrosive nature, is an inorganic ionic compound with chemical formula NaOH. It is used as a base in a lot of industries and applications including, but not limited to, pH regulation, soaps and detergents, salt manufacturing, electrolysis etc. It is produced by electrolysis of brine. Chlorine gas is a by-product of this reaction. Generally, caustic soda manufacturers get into manufacturing of other downstream chlor-alkali products to utilize the chlorine gas. Uses: Acid neutralization, bleaching in papermaking and cotton processing, petroleum refining.Production of alumina from bauxite,Manufacturing synthetic fabrics such as rayon,Production of soaps, detergents, and manufacturing food products.?. Group: Inorganic Chemical. Alternative Names: Caustic Soda. Grades: Technical Grade, Industrial Grade. CAS No. 1310-73-2. Pack Sizes: 25kg LDPE bags with IIP certificate 20' container: 25.5 MT without pallets - 1020 bags 20' container: 20 MT with pallets - 800 bags. |  |
| Caustic Soda Flakes - Sodium Hydroxide | Caustic Soda Flakes - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 99.5% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1823. |  |
| Caustic Soda Liq | Liquid - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liq bulk 1310-73-2 | Minimum Quantity 25kgs. Surface Coatings - Buy Caustic Soda. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liquid Drum 1310-73-2 | Liq Drums - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liquid Ibc 1310-73-2 | IBC Plastic Tanks - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Pearl | Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Pearls - Sodium Hydroxide | Caustic Soda Pearls - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 99.5% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1823. | |
| Caustic Soda Solution - Sodium Hydroxide | Caustic Soda Solution - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 50% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1824. | |
| Cautic Soda pearls and flakes | Cautic Soda pearls and flakes. |  International |
| Cavosonstat | Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N91115. CAS No. 1371587-51-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109027. |  |
| CAY10397 | Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). CAY10397 is a selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. It is a selective inhibitor of 15-hydroxy PGDH with IC50 of 10 μM. Synonyms: CK47A. Grades: ≥98%. CAS No. 78028-01-0. Molecular formula: C17H16N2O5. Mole weight: 328.3. | |
| CAY10398 | CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM. It has equivalent selectivity and is much more cost-effective for the inhibition of HDAC. The deacetylation of histones by HDAC is associated with transcriptional silencing. Synonyms: MD 85; PX 089274. Grades: ≥98%. CAS No. 193551-00-7. Molecular formula: C15H23N3O3. Mole weight: 293.4. | |
| CAY10401 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10401 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM. It is approximately 580-fold more potent than oleyl trifluoromethyl ketone. Synonyms: CAY 10401; CAY-10401; 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one. Grades: ≥98%. CAS No. 288862-89-5. Molecular formula: C24H34N2O2. Mole weight: 382.5. | |
| CAY10404 | CAY10404 is a potent, selective COX-2 inhibitor. Synonyms: CAY 10404; CAY-10404; CAY10404; 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole. CAS No. 340267-36-9. Molecular formula: C17H12F3NO3S. Mole weight: 367.4. | |
| CAY10410 | CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. It was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. CAY10410 was not cytotoxic at up to 25 μM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 μM. Synonyms: 9,10-dihydro-15-deoxy-Δ12,14-PGJ2; 9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2. Grades: ≥98% (isomer mixture). CAS No. 596104-94-8. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| CAY10412 | Anandamide (AEA), also known as N-arachidonoylethanolamine, is an endogenous lipid with cannabinergic activity. CAY10412 is an analog of AEA that has no intrinsic binding affinity for either CB1 or CB2 receptors. It is a potent inhibitor of AEA reuptake in U937 lymphoma cells with IC50 of 3 μM. It could be a useful tool for distinguishing the competing transporter theories. CAY10412 may enhance endocannabinoid signalling by augmenting endocannabinoid concentrations. Synonyms: CAY 10412; CAY-10412. Grades: ≥98%. CAS No. 390824-17-6. Molecular formula: C25H36O2S. Mole weight: 400.6. | |
| CAY10416 | CAY10416 is a dual COX-2/5-LO inhibitor. Synonyms: CHEMBL423638; CAY10416; CHEMBL 423638; CAY 10416; CHEMBL-423638; CAY-10416; ; 43919-96-8; 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole; 3-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-(4-(methylsulfonyl)phenyl)-5-phenyl-1H-pyraz. CAS No. 443919-96-8. Molecular formula: C29H29FN2O5S. Mole weight: 536.6. | |
| CAY10434 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11 displaying an IC50 value of 8.8 nM when tested in human renal microsomes. It is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Synonyms: CAY 10434; CAY-10434. Grades: ≥98%. CAS No. 769917-29-5. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
| CAY10435 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH with Ki value of 0.57 nM. It exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Synonyms: CAY 10435; CAY-10435. Grades: ≥98%. CAS No. 288862-73-7. Molecular formula: C18H26N2O2. Mole weight: 302.4. | |
| CAY10443 | Mitochondrial release of cytochrome c triggers apoptosis including caspase-9, which is called the apoptosome. Apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs. CAY10443 is an apoptotic activators and activated caspase-3 with an EC50 of 5 μM. Synonyms: (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate. Grades: ≥98%. CAS No. 582314-48-5. Molecular formula: C17H15Cl2NO2. Mole weight: 336.2. | |
| CAY10444 | CAY10444 is a S1P3 (shingosine-1-phosphate receptor) specific antagonist. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CAY10444; CAY-10444; CAY 10444; BML-241; BML 241; BML241. Product Category: Antagonists. Appearance: Solid powder. CAS No. 298186-80-8. Molecular formula: C15H29NO2S. Mole weight: 287.46. Purity: >98%. IUPACName: (4R)-2-Undecyl-4-thiazolidinecarboxylic acid. Canonical SMILES: O=C([C@H]1NC(CCCCCCCCCCC)SC1)O. Product ID: ACM298186808-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| CAY10444 | CAY10444 is a family of related G-protein coupled receptors that bind sphingosine-1 phosphate (S1P) as a high-affinity ligand have recently been cloned. It is a selective antagonist of S1P binding to the S1P3 receptor, blocking the calcium increase in HeLa cells by about 40% when present at 10 μM. Synonyms: BML-241; CAY 10444; CAY-10444; BML 241. Grades: ≥98%. CAS No. 298186-80-8. Molecular formula: C15H29NO2S. Mole weight: 287.5. | |
| CAY10448 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel. It is also an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of 10 nM. Synonyms: CAY 10448; CAY-10448. Grades: ≥98%. CAS No. 1177195-52-6. Molecular formula: C18H28INO3. Mole weight: 433.3. | |
| CAY10449 | CAY10449 is one of compounds which are found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase. It also inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 3 nM. Synonyms: CAY 10449; CAY-10449. Grades: ≥98%. Molecular formula: C19H21N3O2. Mole weight: 323.4. | |
| CAY10462 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. Synonyms: CAY 10462; CAY-10462. Grades: ≥98%. CAS No. 502656-68-0. Molecular formula: C17H25N3O·2HCl. Mole weight: 360.3. | |
| CAY 10462 dihydrochloride | CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. CAY 10434 dihydrochloride improves contractile response to angiotensin II with the maximal contractile response (E max ) 6764 mg [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 502656-68-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120648A. | |
| CAY10464 | CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a K i of 1.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR antagonist 7. CAS No. 688348-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112628. | |
| CAY10464 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics. CAY10464 is a potent and selective AhR antagonist with a Ki of 1.4 nM. It is inactive as an estrogen receptor ligands even used at 100 μM. Synonyms: CAY 10464; CAY-10464. Grades: ≥98%. CAS No. 688348-37-0. Molecular formula: C15H12Cl2O. Mole weight: 279.2. | |
| CAY10465 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor. CAY10465 is an analog of resveratrol which acts as a potent and selective AHR receptor agonist with Ki of 0.2 nM. It is inactive as a ligand for the estrogen receptor. Synonyms: CAY 10465; CAY-10465. Grades: ≥98%. CAS No. 688348-33-6. Molecular formula: C15H9Cl2F3. Mole weight: 317.1. | |
| CAY10471 | CAY10471 is an analog of BAY-u3405, which contains modifications that increase both its potency and selectivity for the human CRTH2/DP2 receptor. CAY10471 binds to the human DP1 with Ki of 1200 nM and DP2 with Ki of 0.6 nM. It also show very high binding affinity with TP, which Ki can higher than 10,000 nM. Synonyms: CAY-10471; CAY 10471; TM-30089; TM 30089. Grades: ≥95%. CAS No. 627865-18-3. Molecular formula: C21H21FN2O4S. Mole weight: 416.5. | |
| CAY10485 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
| CAY10486 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
| CAY10498 | The A1, A2A, A2B, and A3 adenosine receptors (ARs) are ubiquitous G protein-coupled receptors. A3 AR antagonists are of interest as therapeutic agents in glaucoma agents and inflammation. CAY10498 is a potent and selective Adenosine A3-R (A3 AR) antagonist exhibiting a Ki of 37 nM. It is 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively. CAY10498 is also a structural analog of reversine, which is a dedifferentiation agent of embryonic progenitor cells. Synonyms: 2-phenyl-amino-N6-endo-norbornyladenine. Grades: ≥95%. CAS No. 863202-33-9. Molecular formula: C18H20N6. Mole weight: 320.4. | |
| CAY10499 | Monoglyceride lipase (MGL) plays an important role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). CAY10499 is a potent and selective monoglyceride lipase (MGL) inhibitor exhibiting an IC50 of 90 nM for the recombinant enzyme. It is also a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 mM, respectively). Synonyms: CAY-10499; CAY 10499; Magl-IN-5. Grades: ≥98%. CAS No. 359714-55-9. Molecular formula: C18H17N3O5. Mole weight: 355.34. | |
| CAY10502 | Phospholipases A2 (PLA2s) are enzymes that cleave fatty acid in position two of phospholipids, hydrolyzing the bond between the second fatty acid "tail" and the glycerol molecule. It catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. CAY10502 is a potent Calcium-dependent cytosolic PLA2 (cPLA2α) inhibitor with IC50 value of 4.3 nM for the purified enzyme from human platelets. It inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively. Synonyms: CAY10502; CAY-10502. Grades: ≥98% (mixture of isomers). CAS No. 888320-29-4. Molecular formula: C30H37NO7. Mole weight: 523.6. | |
| CAY10505 | CAY10505 is a phosphatidylinositol 3-kinase-γ inhibitor, was found to significantly improve acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats. CAY10505, may improve hypertension-associated vascular endothelial dysfunction. Inhibition of PI3Kγ might be a useful approach in the therapeutics of vascular endothelium dysfunction. Synonyms: CAY10505; CAY 10505; CAY-10505. Grades: 0.98. CAS No. 1218777-13-9. Molecular formula: C14H8FNO3S. Mole weight: 289.28. | |
| CAY10506 | Peroxisome proliferator-activated receptor gamma (PPARγ), also known as the glitazone receptor, or NR1C3, is a type II nuclear receptor that in humans is encoded by the PPARG gene. CAY10506 is a PPARγ agonist, which is a nuclear transcription factor that controls lipid homeostasis and glucose metabolism. It is a hybrid lipoic acid (anti-diabetic drugs of the thiazolidinedione) TZD derivative that transactivates human PPARγ with an EC50 value of 10 μM. Synonyms: CAY 10506; CAY-10506. Grades: ≥98%. CAS No. 292615-75-9. Molecular formula: C20H26N2O4S3. Mole weight: 454.6. | |
| CAY10508 | Cannabinoid receptor type 1 (CB1) is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. The human CB1 receptor is expressed in the peripheral nervous system and central nervous system. CAY10508 is a potent and selective central cannabinoid (CB1) receptor inverse agonist with a Ki value of 243 nM and an EC50 of 195 nM. Synonyms: CAY 10508; CAY-10508. Grades: ≥98%. CAS No. 878533-35-8. Molecular formula: C21H14Br2N2O2. Mole weight: 486.2. | |
| CAY10509 | Prostaglandin F2α (PGF2α in prostanoid nomenclature) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. CAY10509 is an analog of PGF2α containing a thio-fluorobenzene substituent in the lower side chain, which has an IC50 of about 30 nM for binding to the recombinant human FP receptor. Synonyms: CAY 10509; CAY-10509. Grades: ≥98%. CAS No. 1245699-47-1. Molecular formula: C23H35FO5S. Mole weight: 442.6. | |
| CAY10510 | Prostaglandin F2α (PGF2α in prostanoid nomenclature) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. CAY10510 is an analog of PGF2α containing an acetylenic fluorobenzene substituent in the lower side chain, which has an IC50 of 0.5 nM when tested for binding to the recombinant human FP receptor. Synonyms: CAY 10510; CAY-10510. Grades: ≥98%. CAS No. 291303-34-9. Molecular formula: C24H33FO5. Mole weight: 420.5. | |
| Cay10512 | Cay10512. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CAY10512, SureCN158576, AGN-PC-003SSH, CTK8E8854, CTK8G1811, AG-L-66358, 1-fluoro-2-[(E)-2-(4-methoxyphenyl)ethenyl]benzene, 139141-12-1. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 139141-12-1. Molecular formula: C15H13FO. Mole weight: 228.3. Purity: 0.96. IUPACName: 1-fluoro-2-[2-(4-methoxyphenyl)ethenyl]benzene. Product ID: ACM139141121. Alfa Chemistry ISO 9001:2015 Certified. | |
| CAY10512 | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CAY10512 is an analog of Resveratrol that is 100-fold more potent (IC50 = 150 nM) at inhibiting NF-κB activation by TNF-&alpha. Unlike Resveratrol and some other trans-stilbene analogs, CAY10512 does not exhibit antioxidant activity (up to 15 μM) in either the ferric reducing/antioxidant power (FRAP) or total radical antioxidant parameter (TRAP) assays. Synonyms: (E)-2-Fluoro-4?-methoxystilbene. Grades: ≥97%. CAS No. 139141-12-1. Molecular formula: C15H13FO. Mole weight: 228.3. | |
| CAY10514 | 8(S)-HETE is a strong activator of peroxisome proliferator-activated receptors α (PPARα) and a weak activator of peroxisome proliferator-activated receptors γ (PPARγ). CAY10514 is an aromatic analog of 8(S)-HETE, which acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively. Synonyms: Methyl-8-hydroxy-8-(2-pentyl-oxyphenyl)-oct-5-ynoate. Grades: ≥98%. CAS No. 868526-38-9. Molecular formula: C20H28O4. Mole weight: 332.4. | |
| CAY10535 | TPα and TPβ are two isoforms of the human TP receptor, which is the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). CAY10535 is a TP receptor antagonist that shows ~20-fold selectivity for TPβ with IC50 of 99 nM than TPα with IC50 of 1970 nM in the inhibition of U46619-mediated Ca2+ mobilization. Synonyms: CAY 10535; CAY-10535. Grades: ≥98%. CAS No. 945716-28-9. Molecular formula: C18H21N3O7S. Mole weight: 423.4. | |
| CAY10554 | Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. Synonyms: BML-259; BML 259; CAY 10554; CAY-10554. Grades: ≥95%. CAS No. 267654-00-2. Molecular formula: C14H16N2OS. Mole weight: 260.4. | |
| CAY10561 | The extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. CAY10561 is a potent, ATP-competitive inhibitor of ERK2 with Ki of 2 nM. It is highly selective for ERK2 and inhibits proliferation of COLO 205 cells with IC50 of 0.54 μM. Synonyms: Pyrazolylpyrrole ERK Inhibitor; CAY 10561; CAY-10561. Grades: ≥98%. CAS No. 933786-58-4. Molecular formula: C22H17Cl2FN4O2. Mole weight: 459.3. | |
| CAY10566 | Stearoyl-CoA desaturase (SCD) is an endoplasmic reticulum enzyme that catalyzes the rate-limiting step in the formation of monounsaturated fatty acids (MUFAs), specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. CAY10566 is a potent and selective inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. It also shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells. Synonyms: CAY 10566; CAY-10566. Grades: ≥98%. CAS No. 944808-88-2. Molecular formula: C18H17ClFN5O2. Mole weight: 389.8. | |
| CAY10567 | AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. CAY10567 is an AKT1 translocation inhibitor. It can prevent the translocation of AKT1 by apparently compromising the function of the PH domain. CAY10567 also inhibits hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase (RdRp) with an IC50 value of 79 μM. Synonyms: BML-257. Grades: ≥98%. CAS No. 32387-96-5. Molecular formula: C21H14N2O2. Mole weight: 326.4. | |
| CAY10570 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10570 is a reversible competitive inhibitor of FAAH activity exhibiting an IC50 value of 1.3 μM. It has no affinity for the human CB1 receptor and acts as a competitive inhibitor of FAAH activity without being hydrolyzed. Synonyms: CAY 10570; CAY-10570. Grades: >98%. CAS No. 875014-22-5. Molecular formula: C25H32N2OS. Mole weight: 408.6. | |
| CAY10571 | CAY10571 is a cell-permeable, reversible, and ATP-competitive sulfone analog of the p38 MAP kinase inhibitor. It is an analog of SB203580, which inhibits IL-1 production in the human monocytic cell line THP with an IC50 value of 0.20 μM and binds CSAID binding protein. Synonyms: CAY 10571; CAY-10571. Grades: ≥95%. CAS No. 152121-46-5. Molecular formula: C21H16FN3O2S. Mole weight: 393.4. | |
| CAY10573 | Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the following three subtypes: PPARα, PPARγ, and PPARβ/&delta. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It shows stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM). Synonyms: CAY 10573; CAY-10573. Grades: ≥98%. CAS No. 853652-40-1. Molecular formula: C33H31NO5. Mole weight: 521.6. | |
| CAY10574 | Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10574, also known as Cdk9 Inhibitor II, is a potent, selective inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with Ki of 13.3 μM and IC50 values 20 μM. Synonyms: CAY 10574; CAY-10574; Cdk9 Inhibitor II. Grades: ≥95%. CAS No. 140651-18-9. Molecular formula: C9H10N6O. Mole weight: 218.2. | |
| CAY10575 | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is activated upon degradation of IκB following IKK-α and IKK-β phosphorylation. IKK-ε, a homolog of IKK-α and IKK-β, can also activate NF-κB. CAY10512 is an analog of Resveratrol that is 100-fold more potent with IC50 of 150 nM at inhibiting NF-κB activation by TNF-&alpha. It does not exhibit antioxidant activity in either the ferric reducing/antioxidant power (FRAP) or total radical antioxidant parameter (TRAP) assays. Synonyms: CAY 10575; CAY-10575. Grades: ≥95%. CAS No. 916985-21-2. Molecular formula: C22H21N3O6S2. Mole weight: 487.6. | |
| CAY10577 | Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. Deregulation of CK2 has been linked to tumorigenesis as a potential protection mechanism for mutated cells. CAY10577 inhibits CK2 with an IC50 value of 0.8 μM. Synonyms: CAY 10577; CAY-10577. Grades: ≥95%. CAS No. 300675-28-9. Molecular formula: C10H5Cl2NO3. Mole weight: 258.1. | |
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