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| Product | Description | |
|---|---|---|
| CCT245737 | CCT245737 is an orally bioactive CHK1 inhibitor (IC50 of 1.4 nM), displaying >1,000-fold selectivity against CHK2 and CDK1. It potently inhibits cellular CHK1 activity (IC50 30-220nM) and enhances gemcitabine and SN38 cytotoxicity in multiple human tumor cell lines and human tumor xenograft models. It causes inhibition of tumor growth in an Eμ-Myc mouse model of human B-cell lymphocytic leukemia. Synonyms: CCT-245737; CCT 245737; CCT245737; 5-[(4-{[(2R)-morpholin-2-ylmethyl]amino}-5-(trifluoromethyl)pyridin-2-yl)amino]pyrazine-2-carbonitrile. CAS No. 1489389-18-5. Molecular formula: C16H16F3N7O. Mole weight: 379.347. |  |
| CCT245737(S) | CCT245737, a nitrogen heterocycle compound, has been found to be a CHK1 inhibitor that could probable be effective in antineoplastic studies. It is still under Phase I trail for Solid tumours. IC50: 30-220 nM. Synonyms: CCT245737; CCT 245737; CCT-245737; GTPL9187; GTPL 9187; GTPL-9187; 5-[[4-[[(2R)-morpholin-2-yl]methylamino]-5-(trifluoromethyl)pyridin-2-yl]amino]pyrazine-2-carbonitrile. Grade: 98%. CAS No. 1489389-23-2. Molecular formula: C16H16F3N7O. Mole weight: 379.14. | |
| CCT251236 | CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction. Uses: Scientific research. Group: Signaling pathways. CAS No. 1693731-40-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101026. |  |
| CCT-251236 | CCT-251236 is an orally active Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen, which exhibited efficacy in a human ovarian carcinoma xenograft model. Uses: The potential treatment of ovarian carcinoma. Synonyms: CCT251236; CCT 251236; N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-2-(2-(pyrrolidin-1-yl)ethoxy)quinoline-6-carboxamide; N-[5-(2,3-dihydro-1,4-benzodioxine-6-amido)-2-methylphenyl]-2-[2-(pyrrolidin-1-yl)ethoxy]quinoline-6-carboxamide; 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-[2-(1-pyrrolidinyl)ethoxy]-. Grade: ≥95%. CAS No. 1693731-40-6. Molecular formula: C32H32N4O5. Mole weight: 552.62. | |
| CCT251545 | CCT251545, a small molecule inhibitor of WNT signaling with oral activity, can be used as a selective chemical probe that exhibits >100-fold selectivity for the human Mediator complex-associated protein kinases CDK8 and CDK19 over 291 other kinases. IC50: Synonyms: 8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-oneCCT251545; CCT 251545; CCT-251545; CHEMBL34082138-(3-chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one8-{3-Chloro-5-[4-(1-Methyl-1h-Pyrazol-4-Yl)ph. CAS No. 1661839-45-7. Molecular formula: C23H24ClN5O. Mole weight: 421.92. | |
| CCT251545 | CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with an IC50 of 5 nM in 7dF3 cells[1]. CCT251545 is a selective chemical probe for exploring the role of CDK8 and CDK19 in human disease[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1661839-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12681. | |
| CCT-251921 | CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor with an IC50 of 2.3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1607837-31-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19984. | |
| CCT-251921 | CCT-251921 has been found to be a CDK inhibitor that could be significant in the studies of colorectal cancer. Synonyms: CCT251921; CCT-251921; CCT 251921; 8-(2-amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one. Grade: 98%. CAS No. 1607837-31-9. Molecular formula: C21H23ClN6O. Mole weight: 410.91. | |
| CCT374705 | CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro. CCT374705 effectively inhibits tumor growth in a lymphoma xenograft mouse model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2640647-90-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153521. | |
| CCTA-1523 | CCTA-1523 is a potent, selective, reversible and orally active ABCG2 inhibitor with anticancer activity. It selectively reverses ABCG2-mediated MDR in cancer cells. Synonyms: Acetamide, 2,2-dichloro-N-(3',4'-dimethoxy[1,1'-biphenyl]-3-yl)-; 2,2-Dichloro-N-(3',4'-dimethoxy[1,1'-biphenyl]-3-yl)acetamide. Grade: ≥95%. CAS No. 1616271-41-0. Molecular formula: C16H15Cl2NO3. Mole weight: 340.20. | |
| CCVJ | CCVJ. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-(2-Carboxy-2-cyanovinyl)julolidine,(2E)-2-Cyano-3-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)acrylicacid. Product Category: Other Fluorophores. Appearance: Red crystalline powder. CAS No. 142978-18-5. Molecular formula: C16H16N2O2. Mole weight: 268.31. Purity: 97%+. IUPACName: (E)-3-(1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)-2-cyanoprop-2-enoicacid. Canonical SMILES: C1CC2=CC(=CC3=C2N(C1)CCC3)/C=C(\C#N)/C(=O)O. Product ID: ACM142978185-2. Alfa Chemistry ISO 9001:2015 Certified. Categories: CCJO René Cassin. |  |
| CCX140-B | CCX140-B is a potent CCR2 antagonist. Synonyms: CCX140; Ilacirnon. CAS No. 1100318-47-5. Molecular formula: C20H13ClF3N5O3S. Mole weight: 495.9. | |
| C-Cys-Mel | C-Cys-Mel. Synonyms: Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-Cys. | |
| CD111/Nectin-1/PVRL1 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| CD12681 | CD12681 is a potent and selective RORγ inverse agonist with IC50 of 19 nM. CD12681 was indentified as a preclinical candidate for the topical treatment of psoriasis. Synonyms: N-(2,4-Dimethylphenyl)-N-isobutyl-2-oxo-1-((tetrahydro-2H-pyran-4-yl)methyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide. Grade: 99%. CAS No. 1952239-59-6. Molecular formula: C25H33N3O4S. Mole weight: 471.61. | |
| CD147 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD-14 from mouse | recombinant, expressed in CHO cells, 90-95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD-14 human | recombinant, expressed in CHO cells, 90-95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD14 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD152/Fc Chimera, Cytolytic from mouse | recombinant, expressed in NS.1 cells, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| CD152/Fc Chimera, Non-cytolytic from mouse | ?98% (SDS-PAGE), recombinant, expressed in NS.1 cells, lyophilized. Group: Fluorescence/luminescence spectroscopy. | |
| CD152 (human): FC (human) (non-lytic) | recombinant, expressed in CHO cells, ?98% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD1530 | CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It was also a potent CYP26A1 inhibitor as ketoconazole with an IC50 value of 530 nM. It inhibited excessive ROS production in tongue epithelial cells in vitro. It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM. It has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis. Synonyms: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid; CD 1530; CD-1530; Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-; 4-[7-(Adamantan-1-yl)-6-hydroxy-2-naphthyl]benzoic acid. Grade: ≥95%. CAS No. 107430-66-0. Molecular formula: C27H26O3. Mole weight: 398.49. | |
| CD1530 | CD1530 is an orally active, selective RAR? agonist and antibacterial agent. CD1530 reduces Smad1/5/8 phosphorylation and overall Smad levels. CD1530 reduces ?-catenin, MMP9 protein, and ROS levels. CD1530 exhibits activities such as inhibiting heterotopic ossification, promoting Achilles tendon healing, and inhibiting muscle fatty infiltration. CD1530 can be used in the research of orthopedic diseases (such as heterotopic ossification, Achilles tendon injury), muscle diseases (such as muscle fatty infiltration-related diseases)[1][2][3][4][5][6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107430-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108527. | |
| CD1530 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CD 1530 | CD 1530. Group: Biochemicals. Grades: Purified. CAS No. 107430-66-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CD155 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD161 | CD161 is a potent, selective and orally active BET bromodomain inhibitor with Ki values of 8.2 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. In human leukemia cell lines MV4-11 and MOLM-13, CD161 strongly inhibits cell growth and induces apoptosis, with IC50s <100 nM. Synonyms: CD-161; CD 161; 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole. Grade: 98%. CAS No. 1627716-22-6. Molecular formula: C26H21N5O2. Mole weight: 435.48. | |
| CD164 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD166/ALCAM human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD19 CAR mRNA (Mouse) | CD19 CAR mRNA (Mouse) expresses mouse CD19 CAR protein. CD19 CAR mRNA can trigger transitory expression of CAR, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA targets CD19 which is a transmembrane glycoprotein primarily expressed on B lymphocytes and is important in B cell activation. CD19 CAR mRNA can be studied in cancer research such as lymphoma and leukemia[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 100 ?g; 500 ?g. Product ID: HY-153084. | |
| CD1E human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD-2 | CD-2 (Part#: 1088) |  |
| CD200 human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD200/OX-2 human | recombinant, expressed in HEK 293 cells, ?98% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD20 (188-196) | CD20 (188-196) is a truncated fragment of a membrane phosphoprotein, CD20, which is expressed on the surface of B cells. CD20 receptor is an important target for immunotherapy against B cell lymphoma. Synonyms: B-lymphocyte antigen CD20 (188-196). Grade: >95%. Molecular formula: C46H77N9O12. Mole weight: 948.16. | |
| CD226 human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD 2314 | CD 2314. Group: Biochemicals. Grades: Purified. CAS No. 170355-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD 2314 | CD 2314 is a potent and selective RARβ receptor agonist (Kd = 145 and >3760 nM for RARβ and RARα receptors, respectively). Synonyms: CD-2314; CD 2314; CD2314; 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)-3-thiophenecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 170355-37-0. Molecular formula: C23H24O2S. Mole weight: 364.5. | |
| CD235 | CD235 is a structurally similar analogue of CD161, which is a potent and orally bioavailable inhibitor of BET bromodomain. Synonyms: 7-(3,5-Dimethyl-1,2-oxazol-4-yl)-4-(6-fluoro-4-quinolinyl)-6-methoxy-2-methyl-9H-pyrimido[4,5-b]indole; 9H-Pyrimido[4,5-b]indole, 7-(3,5-dimethyl-4-isoxazolyl)-4-(6-fluoro-4-quinolinyl)-6-methoxy-2-methyl-. Grade: ≥95%. CAS No. 1627716-57-7. Molecular formula: C26H20FN5O2. Mole weight: 453.47. | |
| CD23 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD244/2B4/SLAMF4 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD244 human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD247 human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD24 (mouse): FC (human) | recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD2665 | CD2665 is an orally active and selective RAR-β,γ antagonist, with K d values of 306 nM, 110 nM for RAR-β and RAR-γ, repectively [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170355-78-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107437. | |
| CD 2665 | CD 2665. Group: Biochemicals. Grades: Purified. CAS No. 170355-78-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD 2665 | CD 2665 is a selective RARβ and RARγ antagonist (KD = 110, 306 and > 1000 nM for RARγ, RARβ and RARα respectively) with no activity at RXRα. CD 2665 is used to abrogate retinoic acid-induced apoptosis, proliferation and differentiation of sebocyte growth. Synonyms: CD2665; CD 2665; CD-2665. 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid. Grade: ≥98% by HPLC. CAS No. 170355-78-9. Molecular formula: C31H34O5. Mole weight: 486.6. | |
| CD270 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD273 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD274 from mouse | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD274 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD276 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD279 (human): FC (human) | recombinant, expressed in CHO cells, ?98% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Cd2+-exporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in protozoa, fungi and plants. Group: Enzymes. Enzyme Commission Number: EC 3.6.3.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4667; Cd2+-exporting ATPase; EC 3.6.3.3. Cat No: EXWM-4667. |  |
| CD2 human | recombinant, expressed in E. coli, 0.5 mg protein/mL. Group: Fluorescence/luminescence spectroscopy. | |
| CD-3 | CD-3 (Part#: 1090) | |
| CD300A human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD300C human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD304/NRP1/Neurophilin-1 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD306/LAIR2 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD30/TNFRSF8 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD31 | CD31 (PECAM-1) is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin ( CPB ). CD31 is also an ER-MP12 antigen , acts as a linker between mechanical stress, metabolism and inflammation. CD31 peptide is able to sustain phosphorylation of the CD31 ITIM 686 and of SHP2 and to inhibit TCR -induced T-cell activation [1] - [5]. Uses: Scientific research. Group: Peptides. Alternative Names: PECAM-1. CAS No. 161374-99-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3444. | |
| CD319/SLAMF7/CRACC human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD3254 | CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 196961-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107399. | |
| CD 3254 | CD 3254. Group: Biochemicals. Grades: Purified. CAS No. 196961-43-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD 3254 | CD 3254 is a selective RXRα agonist with no activity at RARα, RARβ or RARγ receptors. Synonyms: CD3254; CD 3254; CD-3254. 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid. Grade: ≥97% by HPLC. CAS No. 196961-43-0. Molecular formula: C24H28O3. Mole weight: 364.48. | |
| CD34+ Cells Targeted SM102 LNP-EGFP mRNA (m1Ψ) | This product is a LNP prepared from SM102 as the ionizable lipid and modified with CD34 antibody. It's specifically designed for targeted delivery of EGFP mRNA to CD34 positive cells. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. |  |
| CD36 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CD38 inhibitor 1 | CD38 inhibitor 1 is a potent CD38 inhibitor. Synonyms: CD38-IN-78c; MDK-7553. CAS No. 1700637-55-3. Molecular formula: C22H27N3O3S. Mole weight: 413.53. | |
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