A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cbz-O-methyl-L-ser. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBZ-L-SERINE(METHYL ETHER);CBZ-O-METHYL-L-SER;CBZ-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 134807-65-1. Molecular formula: C12H15NO5. Mole weight: 253.25. Product ID: ACM134807651. Alfa Chemistry ISO 9001:2015 Certified.
CC0651
CC0651, a Cdc34 ubiquitin-conjugating enzyme allosteric inhibitor, has been found to restrain the cell proliferation at some extent in cancer cell lines PC-3. IC50: 1.72 uM (inhibited the ubiquitination of p27 Kip1). Uses: Cc0651 is a cdc34 ubiquitin-conjugating enzyme allosteric inhibitor that has been found to restrain the cell proliferation at some extent in cancer cell lines pc-3. ic50: 1.72 um (inhibited the ubiquitination of p27 kip1). Synonyms: CC0651;CC 0651; CC-0651; (2R, 3S, 4S)-5-[4-(3, 5-dichlorophenyl)phenyl]-2, 3-dihydroxy-4-[(2-methoxyacetyl)amino]pentanoicacid; CC0651; 1319207-44-7; 4, 5-Dideoxy-5-(3', 5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-ArabinonicAcid; U94; SCHEMBL14884531. Grades: 95%. CAS No. 1319207-44-7. Molecular formula: C20H21Cl2NO6. Mole weight: 442.29.
CC-1065
CC-1065 is originally isolated from Streptomyces zelensis and its bioactivity was very strong. CC-1065 is against gram-positive bacteria with the MIC=1-10 ng/mL, against most gram-negative bacterial and fungi with the MIC of 1 μg/mL. Synonyms: Antibiotic CC 1065; NSC298223; CCRIS 2174. CAS No. 69866-21-3. Molecular formula: C37H33N7O8. Mole weight: 703.70.
CC-1088
CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). Uses: Cytokine inhibitor. Synonyms: CC1088; CC 1088; CC-1088. 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamide. Grades: ≥98%. CAS No. 467421-06-3. Molecular formula: C17H14N2O3. Mole weight: 294.31.
CC-115
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CC115 ; CC-115; CC 115. Product Category: Inhibitors. Appearance: Red solid powder. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.14. Purity: >98%. IUPACName: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one. Canonical SMILES: O=C1CNC2=NC=C(C3=CC=C(C4=NC=NN4)N=C3C)N=C2N1CC. Product ID: ACM1228013157. Alfa Chemistry ISO 9001:2015 Certified.
CC-115
CC-115, a DNA-PK and mTOR inhibitor, has been found to have probable anticarcinoma effect. IC50:13 nM and 21 nM for DNA-PK and mTOR respectively. Uses: Cc-115 is a dna-pk and mtor inhibitor and has been found to have probable anticarcinoma effect. Synonyms: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one; CC115 ; CC-115; CC 115. Grades: 98%. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.35.
CC-115 hydrochloride
The hydrochloride salt form of CC-115 which is a mTOR / DNA-PK inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. IC50: 21 nM and 13 nM for mTOR and DNA-PK respectively. Uses: The hydrochloride salt form of cc-115 which is a mtor / dna-pk inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. Synonyms: CC115 hydrochloride ; CC-115 hydrochloride; CC 115 hydrochloride. Grades: 98%. CAS No. 1300118-55-1. Molecular formula: C16H17ClN8O. Mole weight: 372.81.
CC-12074
A Metabolite of Pomalidomide. Uses: Pomalidomide metabolite. Synonyms: CC-12074; CC12074; CC 12074; Pomalidomide metabolite M19; UNII-A480CC1Z8I; SCHEMBL3742152.4-amino-2-(5-hydroxy-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Grades: ≥98%. CAS No. 460741-57-5. Molecular formula: C13H11N3O5. Mole weight: 289.24.
CC122
CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial. Uses: Cc122 has antitumor and immunomodulatory activity. it is used for the treatment of chronic lymphocytic leukemia. Synonyms: 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione;CC-122; CC122; CC 122. Grades: >98 %. CAS No. 1015474-32-4. Molecular formula: C14H14N4O3. Mole weight: 286.29.
CC-17368
CC-17368 is a hydroxyisoindole derivative and metabolite of pomalidomide that has potential activity in anticancer study like multiple myeloma. Synonyms: CC 17368; CC17368; Pomalidomide metabolite M17; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-. Grades: 98%. CAS No. 1547162-41-3. Molecular formula: C13H11N3O5. Mole weight: 289.25.
CC-17369
CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma. Synonyms: CC-17369; CC 17369; CC17369; Pomalidomide metabolite M16; M16(CC-17369); SCHEMBL15439588; 4-amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindole-1,3-dione. Grades: 98%. CAS No. 1547162-46-8. Molecular formula: C13H11N3O5. Mole weight: 289.25.
CC-223
CC-223, a mTOR kinase inhibitor, has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. It is still under Phase I/II clinical trial by Celgene Corporation. IC50: 16 nM. Uses: Cc-223 is a mtor kinase inhibitor that has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. Synonyms: CC-223; CC 223; CC223; UNII-I8RA3543SY; I8RA3543SY; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyraz. Grades: 98%. CAS No. 1228013-30-6. Molecular formula: C21H27N5O3. Mole weight: 397.47.
CC2BP
CC2BP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(4-(9H-3,9'-bicarbazol-9-yl)phenyl)methanone. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1233215-35-4. Molecular formula: C61H38N4O. Mole weight: 842.98 g/mol. Product ID: ACM1233215354. Alfa Chemistry ISO 9001:2015 Certified. Categories: CCBP2.
CC-3052
CC-3052, a thalidomide analogue, reduces persistent activation of the TNF-α system in HIV without markedly impairing neutrophil viability. Synonyms: CC-3052; CC 3052; CC3052; methyl (2R)-2-(3,4-dimethoxyphenyl)-3-(3-oxo-1H-isoindol-2-yl)propanoate. Grades: >98%. CAS No. 216884-02-5. Molecular formula: C20H21NO5. Mole weight: 355.38.
CC4
CC4 is a selective α6β2 and α4β2 nAChR partial agonist (Ki = 12 and 26nM for rat α6β2 and α4β2 receptors, respectively). CC4 stimulates dopamine release from striatal slices in vitro, and attenuates nicotine-induced self-administration and conditional place preference in vivo. Synonyms: CC4; CC 4; CC-4; Alternine; Ethylenedi-cytisine; (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one. Grades: ≥98% by HPLC. CAS No. 492-02-4. Molecular formula: C24H30N4O2. Mole weight: 406.52.
CC4
CC4. Group: Biochemicals. Grades: Purified. CAS No. 492-02-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CC-401
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. The activation of JNK signaling is indentified in many immune-mediated kidney disease models. Thus, as the JNK inhibitor, CC-401 is found to be effective in these renal injury models. Synonyms: CC-401; CC 401; CC401. Grades: >98%. CAS No. 395104-30-0. Molecular formula: C22H24N6O. Mole weight: 388.47.
CC 401 dihydrochloride
CC 401 dihydrochloride is a potent JNK inhibitor (Ki = 25-50 nM). CC 401 competitively binds to ATP-binding site of phosphorylated JNK to inhibit JNK. Uses: Hepatoprotective. Synonyms: CC-401 dihydrochloride; CC 401 dihydrochloride; CC401 dihydrochloride; 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-96-6. Molecular formula: C22H24N6O.2HCl. Mole weight: 461.39.
CC-401 hydrochloride
ATP-competitive, selective JNK inhibitor. Decreases c-Jun transcription activity and proliferation. Decreases cytochrome c release and caspase 3 activation. Shows anti-ischemic, anti-inflammatory and antiapoptotic effects in vivo. Synonyms: CC 401 hydrochloride; CC401 hydrochloride; CC401 HCl. Grades: >98%. CAS No. 1438391-30-0. Molecular formula: C22H25ClN6O. Mole weight: 424.93.
CC-618
CC-618 has been found to be a PPARβ/δ antagonist that could be used to study the potential biological activity of Cys249 at some extent. IC50: 10 μM. Synonyms: 5-Thiazolecarboxamide, 4-methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-; 4-Methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-5-thiazolecarboxamide; CC 618; CC618; 4-Methyl-2-(4-(trifluoromethyl)phenyl)-N-(2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)ethyl)thiazole-5-carboxamide. Grades: 98%. CAS No. 1680204-90-3. Molecular formula: C20H15F6N3O3S2. Mole weight: 523.47.
CC-671
CC-671 is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor with IC50s of 5 and 3 nM, which is used for the treatment of triple negative breast cancer initiated from a phenotypic screen. It is selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 μM, but does inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively). Synonyms: CC671; CC 671. Grades: ≥95%. CAS No. 1618658-88-0. Molecular formula: C28H28N6O4. Mole weight: 512.6.
CC-885
CC-885 is a cereblon (CRBN) modulator with an anti-tumour activity mediated through the cereblon-dependent ubiquitination and degradation of the translation termination factor GSPT1. CC-885 potently suppresses the proliferation of human acute myeloid leukaemia (AML) tumour cell lines. Uses: Antitumor agent. Synonyms: CC 885; CC885; N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea. Grades: 99%. CAS No. 1010100-07-8. Molecular formula: C22H21ClN4O4. Mole weight: 440.88.
CC-90002
CC-90002 is a humanized anti-CD47 monoclonal antibody. CC-90002 binds to CD47 and inhibits CD47-SIRPα interaction. CC-90002 has been used in the research of acute myeloid leukemia. Synonyms: CC 90002; CC90002. CAS No. 2085844-54-6.
CC-90002
CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar K d value. CC-90002 can be used for the research of hematologic malignancies and solid tumors [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2085844-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99172.
CC-90003
Extracellular-signal regulated kinases (ERKs) are a specific subtype of MAPK that have been extensively linked to regulation of synaptic plasticity and memory formation in many systems. CC-90003 is an irreversible and selective inhibitor of ERK1/2 with IC50s in the 10-20 nM range, which shows good kinase selectivity and antitumor activity in a 258-kinase biochemical assay. Synonyms: CC90003; CC 90003. Grades: ≥98%. CAS No. 1621999-82-3. Molecular formula: C22H21F3N6O2. Mole weight: 458.44.
CC-90003
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621999-82-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112570.
CCA tRNA nucleotidyltransferase
The acylation of all tRNAs with an amino acid occurs at the terminal ribose of a 3' CCA sequence. The CCA sequence is added to the tRNA precursor by stepwise nucleotide addition performed by a single enzyme that is ubiquitous in all living organisms. Although the enzyme has the option of releasing the product after each addition, it prefers to stay bound to the product and proceed with the next addition. Group: Enzymes. Synonyms: CCA-adding enzyme; tRNA adenylyltransferase; tRNA cytidylyltransferase; tRNA CCA-pyrophosphorylase; tRNA-nucleotidyltransferase; transfer-RNA nucleotidyltransferase; transfer ribonucleic acid nucleotidyl transferase; C. Enzyme Commission Number: EC 2.7.7.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3284; CCA tRNA nucleotidyltransferase; EC 2.7.7.72; CCA-adding enzyme; tRNA adenylyltransferase; tRNA cytidylyltransferase; tRNA CCA-pyrophosphorylase; tRNA-nucleotidyltransferase; transfer-RNA nucleotidyltransferase; transfer ribonucleic acid nucleotidyl transferase; CTP(ATP):tRNA nucleotidyltransferase; transfer ribonucleate adenylyltransferase; transfer ribonucleate adenyltransferase; transfer RNA adenylyltransferase; transfer ribonucleate nucleotidyltransferase; ATP (CTP):tRNA nucleotidyltransferase; ribonucleic cytidylic cytidylic
Cc-CATH2 is isolated from Coturnix coturnix. Cc-CATH2 showed considerable reduction of cytotoxic activity compared to other avian cathelicidins, with average IC(50) values of 20.18μm.
Cc-CATH3
Cc-CATH3 is isolated from Coturnix coturnix. Cc-CATH3 is an avian antimicrobial peptide (AMP) with 29 amino acids in length containing a broad-spectrum antibacterial activity. Cc-CATH3 showed considerable reduction of cytotoxic activity compared to other avian cathelicidins, with average IC(50) values of 17.16 μm.
CCCP
CCCP. Group: Biochemicals. Grades: Purified. CAS No. 555-60-2. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
CCCP
CCCP is an oxidative phosphorylation ( OXPHOS ) uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Carbonyl cyanide 3-chlorophenylhydrazone; Carbonyl Cyanide m-Chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100941.
CCCP
CCCP inhibits IFN-β production induced by various types of the STING pathway activators, and suppresses the phosphorylation of STING, TBK1, and IRF3 via disrupting the association of STING and TBK1. Synonyms: CCCP; Mesoxalonitrile 3-chlorophenylhydrazone; 2-[ (3-chlorophenyl) hydrazinylidene]propanedinitrile; Carbonyl Cyanide m Chlorophenyl Hydrazone; Carbonyl Cyanide m-Chlorophenyl; Hydrazone; Carbonyl Cyanide meta Chlorophenyl Hydrazone; Carbonyl Cyanide meta-Chlorophenyl Hydrazone; CCCP. CAS No. 555-60-2. Molecular formula: C9H5ClN4. Mole weight: 204.62.
c,c,c-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)-methanesulfonamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C,C,C-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)-methanesulfonamide;1,1,1-Trifluoro-N-[1,2,3,4-tetrahydro-1-(2-methylpropyl)-7-quinolinyl]-methanesulfonamide. Product Category: Heterocyclic Organic Compound. CAS No. 848080-35-3. Molecular formula: C14H19F3N2O2S. Mole weight: 336.37. Purity: 0.96. IUPACName: 1,1,1-trifluoro-N-[1-(2-methylpropyl)-3,4-dihydro-2H-quinolin-7-yl]methanesulfonamide. Canonical SMILES: CC(C)CN1CCCC2=C1C=C(C=C2)NS(=O)(=O)C(F)(F)F. Density: 1.318 g/cm³. Product ID: ACM848080353. Alfa Chemistry ISO 9001:2015 Certified.
CcD1
CcD1 is isolated from Capsicum chinense. It has antifungal activity.
CCF-642
CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable to the first-line multiple myeloma therapeutic bortezomib. Synonyms: 3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone; CCF-642; CCF 642; CCF642. CAS No. 346640-08-2. Molecular formula: C15H10N2O4S3. Mole weight: 378.44.
CCG-100602
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells with an IC50 value of 9.8 μM. CCG-100602 specifically blocks the nuclear localization of MRTF-A, thereby inhibiting the fibrogenic transcription factor SRF. Synonyms: CCG-100602; 1207113-88-9; 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; CHEMBL603141; compound 4g [PMID: 19963382]; 1-(3,5-bis(trifluoromethyl)benzoyl)-N-(4-chlorophenyl)piperidine-3-carboxamide; CCG100602; CCG 100602; GTPL6764; SCHEMBL1534209; BDBM50436237; AKOS040744973; MS-28902; HY-120855; CS-0079376; Q27075763; [3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; 1-[3,5-bis (trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide. Grades: 98%. CAS No. 1207113-88-9. Molecular formula: C21H17ClF6N2O2. Mole weight: 478.8.
CCG 1423
CCG 1423. Group: Biochemicals. Grades: Purified. CAS No. 285986-88-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG-1423
CCG-1423 is a potent inhibitor of RhoA/C-mediated gene transcription. It suppressed invasion of PC-3 prostate cancer cells in a matrigel model of metastasis. It induces intermediate mesoderm differentiation from ESCs. Synonyms: CCG 1423; N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide. Grades: >98%. CAS No. 285986-88-1. Molecular formula: C18H13ClF6N2O3. Mole weight: 454.75.
CCG-1423
CCG-1423 is an inhibitor of Rho/MRTF/SRF pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 285986-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13991.
CCG 203971
CCG 203971. Group: Biochemicals. Grades: Purified. CAS No. 1443437-74-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG 203971
CCG 203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM). CCG 203971 inhibits fibrosis by targeting the MRTF/SRF gene transcription pathway, and inhibits proliferation of SSc-derived dermal fibroblasts. It also suppresses PC-3 cell migration in scratch wound assays (IC50 = 4.2 μM). Synonyms: CCG-203971; CCG 203971; CCG203971. N-(4-Chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1443437-74-8. Molecular formula: C23H21ClN2O3. Mole weight: 408.88.
Ccg 2046
Ccg 2046. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ambcb5105868, NSC98338, MolPort-001-833-136, CID263681, ZINC00390970, NCGC00186019-01, 13017-69-1. Product Category: Heterocyclic Organic Compound. CAS No. 13017-69-1. Molecular formula: C11H10N4. Purity: >99 %. IUPACName: 3-methyl-3-propylcyclopropane-1,1,2,2-tetracarbonitrile. Canonical SMILES: CCCC1(C(C1(C#N)C#N)(C#N)C#N)C. Density: 1.17g/cm³. Product ID: ACM13017691. Alfa Chemistry ISO 9001:2015 Certified. Categories: CCG-2046.
CCG 2046
CCG 2046 is an inhibitor of regulator of G-protein signaling 4 (RGS4). It reduces the RGS4-Gαo protein-protein interaction signal. Synonyms: CCG 2046; CCG2046; CCG-2046; 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile; 1,1,2,2-tetracyano-3-methyl-3-propylcyclopropane. Grades: ≥99% by HPLC. CAS No. 13017-69-1. Molecular formula: C11H10N4. Mole weight: 198.22.
CCG 2046
CCG 2046. Group: Biochemicals. Grades: Purified. CAS No. 13017-69-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG215022
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor (IC50s= 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively), with good selectivity against other closely related kinases such as GRK1 and PKA. Synonyms: 4-(4-fluoro-3-((pyridin-2-ylmethyl)carbamoyl)phenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; CCG215022; CCG 215022; CCG-215022. CAS No. 1813527-81-9. Molecular formula: C26H22FN7O3. Mole weight: 499.5.
CCG-224406
CCG-224406 is a highly selective and potent inhibitor of G Protein-Coupled Receptor Kinase 2 (IC50= 130 nM), with 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. Synonyms: CCG 224406; CCG224406; N-(1H-Indazole-5-yl)-2-oxo-4-[3-(2,6-dimethoxybenzylcarbamoyl)-4-fluorophenyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide. Grades: >98%. CAS No. 1870843-22-3. Molecular formula: C29H27FN6O5. Mole weight: 558.57.
CCG 232601
CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally. Synonyms: N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601. Grades: 99%. CAS No. 1922099-21-5. Molecular formula: C24H20ClF2N3O2. Mole weight: 455.88.
CCG273441
CCG273441 is a covalent inhibitor of G protein-coupled receptor ( GPCR ) kinase 5 ( GRK5 ) with an IC 50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC 50 =4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2750414-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-47573.
CCG 50014
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM, exhibiting >20-fold selectivity over other RGS proteins. Synonyms: CCG50014; CCG-50014; 4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione. Grades: >98%. CAS No. 883050-24-6. Molecular formula: C16H13FN2O2S. Mole weight: 316.35.
CCG 50014
CCG 50014. Group: Biochemicals. Grades: Purified. CAS No. 883050-24-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG 63802
CCG 63802. Group: Biochemicals. Grades: Purified. CAS No. 620112-78-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG-63802
CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein. It is selective amongst RGS proteins, with greatest potency at RGS4. It also inhibits GTPase accelerating protein activity of RGS4, blocks its interaction with Gαo, and retains activity under reducing conditions. Synonyms: CCG-4986; CCG 4986; CCG4986. Grades: >98%. CAS No. 620112-78-9. Molecular formula: C26H18N4O2S. Mole weight: 450.51.
CCG-63808
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Synonyms: CCG-63808; CCG 63808; CCG63808. Grades: >98%. CAS No. 620113-73-7. Molecular formula: C25H15FN4O2S. Mole weight: 454.48.
Cc-GRP
Cc-GRP is a peptide with a molecular weight of 7kDa and it was observed to display homology to GRPs. Cc-GRP has antifungal activity.
Cci I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. T↑CATGA AGTAC↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1094RE.
CciN I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GC↑GGCCGC CGCCGG↓CG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus N. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Store at -20°C. Cat No: ET-1095RE.
CCK (26-30) (sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-30) is an N-terminal fragment of CCK, the sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-30) (sulfated). Grades: ≥95%. CAS No. 89911-69-3. Molecular formula: C33H41N7O12S2. Mole weight: 791.85.
CCK (26-31) (sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-31) is an N-terminal fragment of CCK, the sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-31) (sulfated). Grades: ≥95%. CAS No. 89911-65-9. Molecular formula: C38H50N8O13S3. Mole weight: 923.05.
CCK (27-33) (non-sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (27-33) is a C-terminal fragment of CCK. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes with IC50 of 4 μM and inhibits electrically-stimulated contraction of isolated guinea pig ileum with IC50 of 17 μM. Synonyms: Cholecystokinin (27-33) (non-sulfated). Grades: ≥95%. CAS No. 47910-79-2. Molecular formula: C45H57N9O10S2. Mole weight: 948.12.
CCK-4 Acetate
Tetragastrin is a tetrapeptide. Synonyms: CCK-4; CCK4; CCK 4; Gastrin Tetrapeptide; Cholecystokinin Octapeptide (5-8); Cholecystokinin Tetrapeptide; Gastrin (14-17) (human). CAS No. 35144-91-3. Molecular formula: C29H36N6O6S. Mole weight: 596.70.
CCK Octapeptide (non-sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). Grades: 98%. CAS No. 25679-24-7. Molecular formula: C49H62N10O13S2. Mole weight: 1063.
CCK Octapeptide, non-sulfated
CCK Octapeptide, non-sulfated. Group: Biochemicals. Grades: Purified. CAS No. 25679-24-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CCK Octapeptide, sulfated
CCK Octapeptide, sulfated. Group: Biochemicals. Grades: Purified. CAS No. 25126-32-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CCL27
CCL27 is a chemotactic factor that attracts skin-associated memory T-lymphocytes. It may play a role in mediating homing of lymphocytes to cutaneous sites. Synonyms: C-C Motif Chemokine Ligand 27.
Cc-LTP1
Cc-LTP1 is produced by Coffea canephora. It has active antifungal activity against Candida albicans.
CCMI
CCMI is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR). It was shown to induce positive modulation of acetylcholine (ACh)-induced EC5 currents (EC50 = 0.7 μM). CCMI enhances cognition in rodent models. Synonyms: AVL-3288; AVL 3288; AVL3288; XY-4083; XY 4083; XY4083; [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide; (Z)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide. CAS No. 917837-54-8. Molecular formula: C19H15Cl2N3O2. Mole weight: 388.25.
CCMI
CCMI. Group: Biochemicals. Grades: Purified. CAS No. 917837-54-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCMI
CCMI (AVL-3288) is a potent and selective α7 nAChR -positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVL-3288; UCI-4083. CAS No. 917837-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12150.
cCMP
cCMP, an intriguing cyclic cytidine monophosphate compound extensively utilized in the realm of biomedical research, has emerged as an invaluable protagonist. Affiliated with the intricacies of various signaling pathways, it conveniently serves as a second messenger, facilitating a comprehensive comprehension of cCMP's involvement in pivotal cellular functions. In the realm of immunology, its versatile nature enables it to diligently modulate the immune response, thus exhibiting promising potential in the battle against inflammatory diseases and cancerous afflictions. Synonyms: Cytidine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 54925-33-6. Molecular formula: C9H11N3O7P · Na. Mole weight: 327.2.