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| Product | Description | |
|---|---|---|
| Catnip flower oil | 100g Pack Size. Group: Analytical Reagents, Aroma Chemicals, Biochemicals, Building Blocks, Flavours and Fragrance Materials. Formula: N/A. CAS No. 8023-84-5. Prepack ID 90028569-100g. See USA prepack pricing. |  |
| Catnip fluid extract | Catnip fluid extract. Uses: Designed for use in research and industrial production. Additional or Alternative Names: catnipoil;CATNIP;CATNIP FLUID EXTRACT;CATNIP HERB FLUID EXTRACT. Product Category: Heterocyclic Organic Compound. CAS No. 8023-84-5. Product ID: ACM8023845. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Catnip Herb Powder (Nepeta Cataria) | Catnip Herb Powder (Nepeta Cataria). |  CA, FL & NJ |
| Catocene | 1g Pack Size. Group: Catalysts, Research Organics & Inorganics. Formula: C27H32Fe2. CAS No. 37206-42-1. Prepack ID 90028870-1g. Molecular Weight 468.25. See USA prepack pricing. | |
| Catonic Yellow X-6G | Catonic Yellow X-6G. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Basic Yellow 13; Catonic Yellow X-8GL. CAS No. 12217-50-4. Molecular formula: C20H23ClN2O. Mole weight: 342.86. Product ID: ACM12217504. Alfa Chemistry ISO 9001:2015 Certified. | |
| CATPB | CATPB is a human FFA2 inverse agonist (pKi = 7.87). It increases forskolin-induced cAMP production, and inhibits acetate-induced MAPK signaling in cells expressing human FFA2. Synonyms: (S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid. Grades: ≥98% by HPLC. CAS No. 1322598-09-3. Molecular formula: C19H17ClF3NO3. Mole weight: 399.79. |  |
| CATPB | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Cats Claw Extract (Ratio) | Cats Claw Extract (Ratio). Group: Others. Purity: 4:1~20:1. Cats Claw Extract (Ratio). Cat No: EXTW-029. |  |
| Cats Claw Powder & P.E. 4:1 (Uncaria Tormentosa) | Cats Claw Powder & P.E. 4:1 (Uncaria Tormentosa). | CA, FL & NJ |
| Catuaba Bark Powder & P.E. 4:1 (Erythroxylum Catuaba) | Catuaba Bark Powder & P.E. 4:1 (Erythroxylum Catuaba). | CA, FL & NJ |
| Catumaxomab | Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 509077-98-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9954. |  |
| CAU | CAU (FCpApU) is an anticodon of the initiator tRNA (tRNAfMet). CAU is the major determinant for aminoacylation of tRNAfMet by MetRS [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CpApU. CAS No. 3022-32-0. Pack Sizes: 1 mg. Product ID: HY-159850. | |
| Caudatin | Caudatin. Group: Biochemicals. Grades: Plant Grade. CAS No. 38395-02-7. Pack Sizes: 20mg. Molecular Formula: C28H42O7, Molecular Weight: 490.63. US Biological Life Sciences. |  Worldwide |
| Cauliflower Powder | Cauliflower Powder. | CA, FL & NJ |
| Caulilexin A | Caulilexin A is a phytoalexin found in Brassica oleracea, which exhibits antifungal activity. Synonyms: Caulilexine A; 2-(Methyldithio)-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2-(methyldithio)-. Grades: ≥95%. CAS No. 905914-67-2. Molecular formula: C10H9NOS2. Mole weight: 223.32. | |
| Cauloside A | Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 17184-21-3. Molecular formula: C35H56O8. Mole weight: 604.81. Purity: 0.98. IUPACName: (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Canonical SMILES: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C2C1)C)C(=O)O)C. Product ID: ACM17184213. Alfa Chemistry ISO 9001:2015 Certified. | |
| Caulosidec(p)(new) | Caulosidec(p)(new). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cauloside C, CID159898, 20853-58-1, 3-((2-0-beta-D-Glucopyranosyl-alpha-L-arabinopyranosyl)oxy)-23-hydroxyolean-12-en-28-oic acid. Product Category: Heterocyclic Organic Compound. CAS No. 20853-58-1. Molecular formula: C41H66O13. Mole weight: 766.96. Purity: 0.96. IUPACName: (4aS,6aR,6aS,6bR,10S,12aR,14bR)-10-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbo. Product ID: ACM20853581. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cauloside F | Cauloside F. Group: Biochemicals. Alternative Names: Cauloside G. Grades: Plant Grade. CAS No. 60451-47-0. Pack Sizes: 10mg. Molecular Formula: C60H98O27, Molecular Weight: 1251.4. US Biological Life Sciences. | Worldwide |
| Caustic potash | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| Caustic Potash 1310-58-3 | Caustic Potash - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Caustic Potash Liquid | Caustic Potash Liquid - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Potash (wet and dry) | Caustic Potash (wet and dry) |  |
| Caustic soda | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. | |
| Caustic Soda | We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. |  California |
| Caustic Soda | Cas No. 68988-74-9. | |
| Caustic Soda 1310-73-2 | Minimum Quantity 25Kgs. Surface Coatings SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda 25%, 50%, lake & beads | 25%, 50%, lake & beads | |
| Caustic Soda 99% | Caustic Soda 99%. Market: Food Additives / Preservatives. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries. |  |
| Caustic Soda Flakes | Sodium Hydroxide or Caustic Soda, also known as lye due to its corrosive nature, is an inorganic ionic compound with chemical formula NaOH. It is used as a base in a lot of industries and applications including, but not limited to, pH regulation, soaps and detergents, salt manufacturing, electrolysis etc. It is produced by electrolysis of brine. Chlorine gas is a by-product of this reaction. Generally, caustic soda manufacturers get into manufacturing of other downstream chlor-alkali products to utilize the chlorine gas. Uses: Acid neutralization, bleaching in papermaking and cotton processing, petroleum refining.Production of alumina from bauxite,Manufacturing synthetic fabrics such as rayon,Production of soaps, detergents, and manufacturing food products.?. Group: Inorganic Chemical. Alternative Names: Caustic Soda. Grades: Technical Grade, Industrial Grade. CAS No. 1310-73-2. Pack Sizes: 25kg LDPE bags with IIP certificate 20' container: 25.5 MT without pallets - 1020 bags 20' container: 20 MT with pallets - 800 bags. |  |
| Caustic Soda Flakes - Sodium Hydroxide | Caustic Soda Flakes - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 99.5% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1823. |  |
| Caustic Soda Liq | Liquid - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liq bulk 1310-73-2 | Minimum Quantity 25kgs. Surface Coatings - Buy Caustic Soda. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liquid Drum 1310-73-2 | Liq Drums - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Liquid Ibc 1310-73-2 | IBC Plastic Tanks - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Pearl | Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Caustic Soda Pearls - Sodium Hydroxide | Caustic Soda Pearls - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 99.5% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1823. | |
| Caustic Soda Solution - Sodium Hydroxide | Caustic Soda Solution - Sodium Hydroxide. Group: Industrial Chemicals. Purity: Purity: 50% Min. CAS No. 1310-73-2. Molecular formula: Molecular formula: NaOH. UN no: 1824. | |
| Caveolin-1 Scaffolding Domain Peptide, Cell-permeable | Caveolin-1 scaffolding domain peptide (C1-SD82-101) fused at the N-terminus to the cell-permeable Antennapedia internalization sequence (43-58). Group: Fluorescence/luminescence spectroscopy. | |
| Caveolin-1 Scaffolding Domain Peptide, Cell-permeable, Negative Control | A scrambled caveolin-1 scaffolding domain peptide (C1-SD82-101) fused at the N-terminus to the Antennapedia internalization sequence (43-58). Group: Fluorescence/luminescence spectroscopy. | |
| Cavosonstat | Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N91115. CAS No. 1371587-51-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109027. | |
| CAY10397 | >98%, solid. Group: Fluorescence/luminescence spectroscopy. | |
| CAY10397 | Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). CAY10397 is a selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. It is a selective inhibitor of 15-hydroxy PGDH with IC50 of 10 μM. Synonyms: CK47A. Grades: ≥98%. CAS No. 78028-01-0. Molecular formula: C17H16N2O5. Mole weight: 328.3. | |
| CAY10398 | CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM. It has equivalent selectivity and is much more cost-effective for the inhibition of HDAC. The deacetylation of histones by HDAC is associated with transcriptional silencing. Synonyms: MD 85; PX 089274. Grades: ≥98%. CAS No. 193551-00-7. Molecular formula: C15H23N3O3. Mole weight: 293.4. | |
| CAY10401 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10401 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM. It is approximately 580-fold more potent than oleyl trifluoromethyl ketone. Synonyms: CAY 10401; CAY-10401; 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one. Grades: ≥98%. CAS No. 288862-89-5. Molecular formula: C24H34N2O2. Mole weight: 382.5. | |
| CAY10404 | CAY10404 is a potent, selective COX-2 inhibitor. Synonyms: CAY 10404; CAY-10404; CAY10404; 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole. CAS No. 340267-36-9. Molecular formula: C17H12F3NO3S. Mole weight: 367.4. | |
| CAY10410 | CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. It was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. CAY10410 was not cytotoxic at up to 25 μM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 μM. Synonyms: 9,10-dihydro-15-deoxy-Δ12,14-PGJ2; 9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2. Grades: ≥98% (isomer mixture). CAS No. 596104-94-8. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| CAY10412 | Anandamide (AEA), also known as N-arachidonoylethanolamine, is an endogenous lipid with cannabinergic activity. CAY10412 is an analog of AEA that has no intrinsic binding affinity for either CB1 or CB2 receptors. It is a potent inhibitor of AEA reuptake in U937 lymphoma cells with IC50 of 3 μM. It could be a useful tool for distinguishing the competing transporter theories. CAY10412 may enhance endocannabinoid signalling by augmenting endocannabinoid concentrations. Synonyms: CAY 10412; CAY-10412. Grades: ≥98%. CAS No. 390824-17-6. Molecular formula: C25H36O2S. Mole weight: 400.6. | |
| CAY10416 | CAY10416 is a dual COX-2/5-LO inhibitor. Synonyms: CHEMBL423638; CAY10416; CHEMBL 423638; CAY 10416; CHEMBL-423638; CAY-10416; ; 43919-96-8; 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole; 3-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-(4-(methylsulfonyl)phenyl)-5-phenyl-1H-pyraz. CAS No. 443919-96-8. Molecular formula: C29H29FN2O5S. Mole weight: 536.6. | |
| CAY10434 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11 displaying an IC50 value of 8.8 nM when tested in human renal microsomes. It is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Synonyms: CAY 10434; CAY-10434. Grades: ≥98%. CAS No. 769917-29-5. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
| CAY10435 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH with Ki value of 0.57 nM. It exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Synonyms: CAY 10435; CAY-10435. Grades: ≥98%. CAS No. 288862-73-7. Molecular formula: C18H26N2O2. Mole weight: 302.4. | |
| CAY10443 | Mitochondrial release of cytochrome c triggers apoptosis including caspase-9, which is called the apoptosome. Apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs. CAY10443 is an apoptotic activators and activated caspase-3 with an EC50 of 5 μM. Synonyms: (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate. Grades: ≥98%. CAS No. 582314-48-5. Molecular formula: C17H15Cl2NO2. Mole weight: 336.2. | |
| CAY10444 | CAY10444 is a family of related G-protein coupled receptors that bind sphingosine-1 phosphate (S1P) as a high-affinity ligand have recently been cloned. It is a selective antagonist of S1P binding to the S1P3 receptor, blocking the calcium increase in HeLa cells by about 40% when present at 10 μM. Synonyms: BML-241; CAY 10444; CAY-10444; BML 241. Grades: ≥98%. CAS No. 298186-80-8. Molecular formula: C15H29NO2S. Mole weight: 287.5. | |
| CAY10444 | CAY10444 is a S1P3 (shingosine-1-phosphate receptor) specific antagonist. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CAY10444; CAY-10444; CAY 10444; BML-241; BML 241; BML241. Product Category: Antagonists. Appearance: Solid powder. CAS No. 298186-80-8. Molecular formula: C15H29NO2S. Mole weight: 287.46. Purity: >98%. IUPACName: (4R)-2-Undecyl-4-thiazolidinecarboxylic acid. Canonical SMILES: O=C([C@H]1NC(CCCCCCCCCCC)SC1)O. Product ID: ACM298186808-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| CAY10448 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel. It is also an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of 10 nM. Synonyms: CAY 10448; CAY-10448. Grades: ≥98%. CAS No. 1177195-52-6. Molecular formula: C18H28INO3. Mole weight: 433.3. | |
| CAY10449 | CAY10449 is one of compounds which are found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase. It also inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 3 nM. Synonyms: CAY 10449; CAY-10449. Grades: ≥98%. Molecular formula: C19H21N3O2. Mole weight: 323.4. | |
| CAY10462 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. Synonyms: CAY 10462; CAY-10462. Grades: ≥98%. CAS No. 502656-68-0. Molecular formula: C17H25N3O·2HCl. Mole weight: 360.3. | |
| CAY 10462 dihydrochloride | CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. CAY 10434 dihydrochloride improves contractile response to angiotensin II with the maximal contractile response (E max ) 6764 mg [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 502656-68-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120648A. | |
| CAY10464 | CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a K i of 1.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR antagonist 7. CAS No. 688348-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112628. | |
| CAY10464 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics. CAY10464 is a potent and selective AhR antagonist with a Ki of 1.4 nM. It is inactive as an estrogen receptor ligands even used at 100 μM. Synonyms: CAY 10464; CAY-10464. Grades: ≥98%. CAS No. 688348-37-0. Molecular formula: C15H12Cl2O. Mole weight: 279.2. | |
| CAY10465 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor. CAY10465 is an analog of resveratrol which acts as a potent and selective AHR receptor agonist with Ki of 0.2 nM. It is inactive as a ligand for the estrogen receptor. Synonyms: CAY 10465; CAY-10465. Grades: ≥98%. CAS No. 688348-33-6. Molecular formula: C15H9Cl2F3. Mole weight: 317.1. | |
| CAY10471 | CAY10471 is an analog of BAY-u3405, which contains modifications that increase both its potency and selectivity for the human CRTH2/DP2 receptor. CAY10471 binds to the human DP1 with Ki of 1200 nM and DP2 with Ki of 0.6 nM. It also show very high binding affinity with TP, which Ki can higher than 10,000 nM. Synonyms: CAY-10471; CAY 10471; TM-30089; TM 30089. Grades: ≥95%. CAS No. 627865-18-3. Molecular formula: C21H21FN2O4S. Mole weight: 416.5. | |
| CAY10485 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
| CAY10486 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
| CAY10498 | The A1, A2A, A2B, and A3 adenosine receptors (ARs) are ubiquitous G protein-coupled receptors. A3 AR antagonists are of interest as therapeutic agents in glaucoma agents and inflammation. CAY10498 is a potent and selective Adenosine A3-R (A3 AR) antagonist exhibiting a Ki of 37 nM. It is 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively. CAY10498 is also a structural analog of reversine, which is a dedifferentiation agent of embryonic progenitor cells. Synonyms: 2-phenyl-amino-N6-endo-norbornyladenine. Grades: ≥95%. CAS No. 863202-33-9. Molecular formula: C18H20N6. Mole weight: 320.4. | |
| CAY10499 | Monoglyceride lipase (MGL) plays an important role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). CAY10499 is a potent and selective monoglyceride lipase (MGL) inhibitor exhibiting an IC50 of 90 nM for the recombinant enzyme. It is also a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 mM, respectively). Synonyms: CAY-10499; CAY 10499; Magl-IN-5. Grades: ≥98%. CAS No. 359714-55-9. Molecular formula: C18H17N3O5. Mole weight: 355.34. | |
| CAY10499 | CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC50 values of 144 nM and 14 nM for monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), respectively. Additionally, CAY10499 exhibits anti-inflammatory and antiviral activities[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MAGL-IN-5. CAS No. 359714-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119283. | |
| CAY10502 | Phospholipases A2 (PLA2s) are enzymes that cleave fatty acid in position two of phospholipids, hydrolyzing the bond between the second fatty acid "tail" and the glycerol molecule. It catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. CAY10502 is a potent Calcium-dependent cytosolic PLA2 (cPLA2α) inhibitor with IC50 value of 4.3 nM for the purified enzyme from human platelets. It inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively. Synonyms: CAY10502; CAY-10502. Grades: ≥98% (mixture of isomers). CAS No. 888320-29-4. Molecular formula: C30H37NO7. Mole weight: 523.6. | |
| CAY10505 | CAY10505 is a phosphatidylinositol 3-kinase-γ inhibitor, was found to significantly improve acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats. CAY10505, may improve hypertension-associated vascular endothelial dysfunction. Inhibition of PI3Kγ might be a useful approach in the therapeutics of vascular endothelium dysfunction. Synonyms: CAY10505; CAY 10505; CAY-10505. Grades: 0.98. CAS No. 1218777-13-9. Molecular formula: C14H8FNO3S. Mole weight: 289.28. | |
| CAY10506 | Peroxisome proliferator-activated receptor gamma (PPARγ), also known as the glitazone receptor, or NR1C3, is a type II nuclear receptor that in humans is encoded by the PPARG gene. CAY10506 is a PPARγ agonist, which is a nuclear transcription factor that controls lipid homeostasis and glucose metabolism. It is a hybrid lipoic acid (anti-diabetic drugs of the thiazolidinedione) TZD derivative that transactivates human PPARγ with an EC50 value of 10 μM. Synonyms: CAY 10506; CAY-10506. Grades: ≥98%. CAS No. 292615-75-9. Molecular formula: C20H26N2O4S3. Mole weight: 454.6. | |
| CAY10508 | Cannabinoid receptor type 1 (CB1) is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. The human CB1 receptor is expressed in the peripheral nervous system and central nervous system. CAY10508 is a potent and selective central cannabinoid (CB1) receptor inverse agonist with a Ki value of 243 nM and an EC50 of 195 nM. Synonyms: CAY 10508; CAY-10508. Grades: ≥98%. CAS No. 878533-35-8. Molecular formula: C21H14Br2N2O2. Mole weight: 486.2. | |
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