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Product
Everolimus Impurity 11 Everolimus Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate. Molecular Formula: C9H19F3O4SSi. Mole Weight: 308.39. Catalog: APB05419. Alfa Chemistry Analytical Products 4
EverolimusImpurity12 EverolimusImpurity12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 12. Molecular Formula: C55H87NO15. Mole Weight: 1002.28. Catalog: APB05418. Alfa Chemistry Analytical Products 4
Everolimus Impurity 13 Everolimus Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 13. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05417. Alfa Chemistry Analytical Products 4
Everolimus Impurity 14 Everolimus Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 14. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05416. Alfa Chemistry Analytical Products 4
Everolimus Impurity 16 Everolimus Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB02225. Alfa Chemistry Analytical Products 4
Everolimus Impurity 211-97 Everolimus Impurity 211-97. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 211-97. Molecular Formula: C52H81NO14. Mole Weight: 944.2. Catalog: APB05422. Alfa Chemistry Analytical Products 4
Everolimus Impurity 23 (Everolimus-13C2-D4) Everolimus Impurity 23 (Everolimus-13C2-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1661009-29-5. Molecular Formula: C5113C2H79D4NO14. Mole Weight: 964.25. Catalog: APB1661009295. Alfa Chemistry Analytical Products
Everolimus Impurity 24 (Everolimus-D4) Everolimus Impurity 24 (Everolimus-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1338452-54-2. Molecular Formula: C53H79D4NO14. Mole Weight: 962.26. Catalog: APB1338452542. Alfa Chemistry Analytical Products
Everolimus Impurity 25 Everolimus Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB07749. Alfa Chemistry Analytical Products 4
Everolimus Impurity 26 Everolimus Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H49NO9. Mole Weight: 591.74. Catalog: APB07750. Alfa Chemistry Analytical Products 4
Everolimus Impurity 27 Everolimus Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB07751. Alfa Chemistry Analytical Products 4
Everolimus Impurity 28 Everolimus Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB07752. Alfa Chemistry Analytical Products 4
Everolimus Impurity 501-95 Everolimus Impurity 501-95. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 501-95. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05421. Alfa Chemistry Analytical Products 4
Everolimus Impurity 6 Everolimus Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1704711-12-5. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB1704711125. Alfa Chemistry Analytical Products
Everolimus Impurity 7 Everolimus Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2402744-97-0. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB2402744970. Alfa Chemistry Analytical Products 2
Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96) Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 9-O-Hydroxyethyl sirolimus(009-96). Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05424. Alfa Chemistry Analytical Products 4
Everolimus Impurity Everolimus-19-ene open ring (804-95) Everolimus Impurity Everolimus-19-ene open ring (804-95). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-(2-((2R, 3R, 6S)-2-hydroxy-6-((2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19E, 21R)-14-hydroxy-22-((1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxodocosa-3, 5, 7, 15, 19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05423. Alfa Chemistry Analytical Products 4
Everolimus Isomer C An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grades: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25. BOC Sciences 8
Everolimus Isomer C Everolimus Isomer C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 908340-97-6. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB908340976. Alfa Chemistry Analytical Products 3
Everolimus O-Desmethyl Impurity (Mixture of Diastereomers) An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grades: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. BOC Sciences 8
Everolimus O-Ethyl Impurity An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 7-O-Desmethyl-7-O-ethyl Everolimus. Grades: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28. BOC Sciences 8
Everolimus Open-Ring Acid Impurity Everolimus Open-Ring Acid Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 769905-89-7. Molecular Formula: C53H85NO15. Mole Weight: 976.25. Catalog: APB769905897. Alfa Chemistry Analytical Products 3
Everolimus O-Silyl Impurity An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin; 42-O-[2-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]ethyl]rapamycin. Grades: > 95%. CAS No. 159351-68-5. Molecular formula: C59H97NO14Si. Mole weight: 1072.52. BOC Sciences 8
Everolimus Related Compound 1 An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: O-Desmethyl Everolimus. Grades: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22. BOC Sciences 8
Everolimus Related Compound 3 Everolimus Ring-Opening Impurity. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid. Grades: 65%. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.75. BOC Sciences 8
Everolimus Related Compound 4 An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R, 3R, 6S)-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 20S, 21R)-14, 20-Dihydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grades: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36. BOC Sciences 8
Everolimus Related Compound 5 Everolimus Related Compound 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2607-52-5. Molecular Formula: C15H22O. Mole Weight: 218.34. Catalog: APB2607525. Alfa Chemistry Analytical Products 2
Everolimus Related Compound 5 An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grades: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. BOC Sciences 8
Everolimus Ring-Opening Impurity An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grades: > 95%. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25. BOC Sciences 8
Evexomostat Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly ({N-[ (2RS) -2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1- (trans-4-{[ ({ (3R, 4S, 5S, 6R) -5-methoxy-4-[ (2R, 3R) -2-methyl-3- (3-methylbut-2-en-1-yl) oxiran-2-yl]-1-oxaspiro[2. 5]-octan-6-yl}oxy) carbonyl]amino}cyclohexyl) glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[ (trans-4-aminocyclohexyl) carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m. BOC Sciences 9
Evifacotrep Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77. BOC Sciences 10
Evinacumab Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7. BOC Sciences 11
Evinacumab Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. MedChemExpress MCE
Evixapodlin Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S, 5'S)-5, 5'- ( ( ( (5, 5'- (2, 2'-dichloro-[1, 1'-biphenyl]-3, 3'-diyl)bis (3-methoxypyrazine-5, 2-diyl))bis (methylene))bis (azanediyl))bis (methylene))bis (pyrrolidin-2-one); 2-Pyrrolidinone, 5, 5'-[ (2, 2'-dichloro[1, 1'-biphenyl]-3, 3'-diyl) bis[ (3-methoxy-5, 2-pyrazinediyl) methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grades: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. BOC Sciences 9
Evobrutinib Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC 50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. MedChemExpress MCE
Evocalcet Evocalcet is a calcium-sensing receptor agonist under the development of Kyowa Hakko Kirin. Phase III clinical trials for Secondary hyperparathyroidism are on-going in Japan. Uses: Secondary hyperparathyroidism. Synonyms: MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; Evocalcet;2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid. Grades: 98%. CAS No. 870964-67-3. Molecular formula: C24H26N2O2. Mole weight: 374.48. BOC Sciences 10
Evocalcet Evocalcet (KHK7580) is an orally active calcium sensing receptor ( CaSR ) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. MedChemExpress MCE
Evodenoson Evodenoson is a selective agonist of the A 2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. MedChemExpress MCE
Evodenoson Evodenoson is a selective A2A adenosine receptor agonist. Phase II clinical trials for the treatment of Glaucoma and Ocular hypertension were discontinued. Uses: Glaucoma;ocular hypertension. Synonyms: ATL313; ATL 313; ATL-313; DE-112; DE 112; DE112; methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate. Grades: 98%. CAS No. 844873-47-8. Molecular formula: C23H29N7O6. Mole weight: 499.53. BOC Sciences 11
Evodiamine Evodiamine is a natural compound with apoptotic activity. It has been found to induce apoptosis in human osteosarcoma cells by binding to pro-apoptotic protein, leading to the activation of caspases and downregulation of Bcl-2. Evodiamine also has synergistic effects with other drugs that induce apoptosis, such as dextran sulfate, an anticancer drug. This compound has shown promising results in clinical trials for breast cancer and resistant breast cancer. The mechanism of action of evodiamine is not fully understood but it may involve autophagy or the induction of plate test. Evodiamine may also have anti-infectious properties due to its ability to inhibit bacteria growth by interfering with DNA binding activity and protein synthesis. Group: Other alkaloids. CAS No. 518-17-2. Molecular formula: C19H17N3O. Mole weight: 303.36 g/mol. Canonical SMILES: CN1[C@@H]2C3=C (CCN2C (=O)C4=CC=CC=C41)C5=CC=CC=C5N3. Catalog: ACM518172. Alfa Chemistry.
Evodiamine Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. MedChemExpress MCE
Evodiamine Evodiamine - Product ID: NST-10-12. Category: Alkaloids. Alternative Names: d-Evodiamine. Purity: 98%. Test method: HPLC. CAS No. 518-17-2. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White to pale yellow powder. Molecular formula: C19H17N3O. Mole weight: 303.36. Storage: +2 … +8 °C. NATURE SCIENCE TECHNOLOGIES
Evodiamine A chemical extracted from Evodia plants, and has been shown to reduce fat uptake. Group: Biochemicals. Alternative Names: (13bS)-8, 13, 13b-14-Tetrahydro-14-methyl-indolo[2', 3':3, 4]pyrido[2, 1-b]quinazolin-5(7H)-one; d-Evodiamine; (+)-Evodiamine. Grades: Highly Purified. CAS No. 518-17-2. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
Worldwide
Evodiamine 98% HPLC Evodiamine 98% HPLC. Pharma Resources International LLC
CA, FL & NJ
Evofosfamide Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Synonyms: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grades: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. BOC Sciences 8
Evofosfamide Evofosfamide (TH-302) is a hypoxia -activated proagent with IC 50 of 10 μM and 1000 μM in hypoxia (N 2 ) and normoxia (21% O 2 ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10535. MedChemExpress MCE
Evogliptin This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one;CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN];1246960-27-9 (HCl). Grades: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. BOC Sciences 10
Evogliptin hydrochloride Evogliptin is a DPP-4 inhibitor, for the treatment of type 2 diabetes mellitus in patients with inadequately controlled by diet and exercise alone, or in combination with metformin when diet and exercise plus metformin alone do not provide satisfactory glycaemic control. CAS No. 1246960-27-9. Molecular formula: C19H27ClF3N3O3. Mole weight: 401.42. BOC Sciences
Evogliptin tartrate Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. MedChemExpress MCE
Evogliptin Tartrate Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. CAS No. 1222102-51-3. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. BOC Sciences 8
Evogliptin Tartrate Impurity S1 An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-6) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. BOC Sciences 8
Evogliptin Tartrate Impurity S2 An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-5) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. BOC Sciences 8
Evogliptin Tartrate Impurity S3 An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. BOC Sciences 8
Evolitrine Evolitrine is an alkaloid isolated from Fructus Evodiae. Synonyms: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. Grades: 98%. CAS No. 523-66-0. Molecular formula: C13H11NO3. Mole weight: 229.23. BOC Sciences 9
Evolocumab Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H 2 O 2 -induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 145. CAS No. 1256937-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9930. MedChemExpress MCE
Evolocumab Evolocumab is a monoclonal antibody as well as an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein targeting LDL receptors. Inhibition of PCSK9 could prevent LDL receptors from degradation and promote the removal of LDL-C from blood circulation. Evolocumab is used for the treatment of hyperlipidemia. Uses: The treatment of hyperlipidemia. Synonyms: AMG 145; AMG-145; AMG145. CAS No. 1256937-27-5. Molecular formula: C6242H9648N1668O1996S56. Mole weight: 141800. BOC Sciences 11
Evolocumab Evolocumab Inhibitor. Uses: Scientific use. Product Category: T9920. CAS No. 1256937-27-5. TARGETMOL CHEMICALS
Evomonoside Evomonoside is a potent natural compound used for studying neurological diseases such as Alzheimer's and Parkinson's. Derived from natural sources, Evomonoside exhibits neuroprotective properties by preventing the formation of amyloid plaques in the brain. Synonyms: (3b,5b)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Digitoxigenin 3-rhamnoside; Digitoxigenin rhamnoside. CAS No. 508-93-0. Molecular formula: C29H44O8. Mole weight: 520.65. BOC Sciences 11
Evoxanthine Evoxanthine is a furanoidone alkaloid isolated from Evodia xanthoxyloides. Evoxanthine is active against Gram-positive and Gram-negative bacteria, including Escherichia coli, Bacillus subtilis and Aspergillus flavus. It has antimalarial and anticancer activities. Synonyms: 11-Methoxy-5-Methyl-1,3-Dioxolo[4.5-B]Acridin-10(5H)-One; 1,3-Dioxolo[4.5-B]Acridin-10(5H)-One. Grades: >95% by HPLC. CAS No. 477-82-7. Molecular formula: C16H13NO4. Mole weight: 283.28. BOC Sciences 6
EVP-0015962 EVP-0015962 is a selective Amyloid precursor protein secretase modulator under the development of FORUM Pharmaceuticals. Chronic treatment with EVP-0015962 can lower the production of Aβ42, attenuate memory deficits, and reduce Aβ plaque formation and inflammation in Tg2576 transgenic animals. EVP-0015962 shows a therapeutic alternative for disease modification in Alzheimer's disease. In Jun 2016, Phase-II for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: EVP-0015962; EVP 0015962; EVP0015962. SCHEMBL3660255; ZSERTYLZGRJLOO-UHFFFAOYSA-N; 2-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclobutylpropanoic acid. Grades: 98%. CAS No. 1447811-26-8. Molecular formula: C22H19ClF6O3. Mole weight: 480.83. BOC Sciences 11
EVP-6124 EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It shows selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs and improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Synonyms: EVP-6124; EVP6124; EVP 6124; MT-4666; MT4666; MT 4666; Encenicline. Grades: >98%. CAS No. 550999-75-2. Molecular formula: C16H17ClN2OS. Mole weight: 320.84. BOC Sciences 10
Evunzekibart Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ATOR-1017. CAS No. 2639688-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990067. MedChemExpress MCE
Evuzamitide Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1420048-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10023. MedChemExpress MCE
EW-7197 EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Synonyms: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grades: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433. BOC Sciences 9
EX1314 BMS-604992 is a selective and orally active growth hormone secretagogue receptor (GHSR) agonist with high-affinity binding (Ki = 2.3 nM) and strong functional activity (EC50 = 0.4 nM). It stimulates feeding in rodents. Synonyms: BMS-604992; Carbamic acid, (2-amino-2-oxoethyl)methyl-, (3-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1,2,4-triazolo(4,3-a)pyridin-5-yl)methyl ester, monohydrochloride; (3-{(1S)-2-(Benzyloxy)-1-[(2-methylalanyl)amino]ethyl}[1, 2, 4]triazolo[4, 3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)methylcarbamate hydrochloride (1:1). Grades: 98%. CAS No. 674343-47-6. Molecular formula: C24H32ClN7O5. Mole weight: 534.01. BOC Sciences 11
EX229 EX229 (compound 991), also known as AMPK Activator 991, is a potent AMPK activator that displays 5-10-fold more potent than A769662 in activating AMPK. Synonyms: Compound 991; AMPK Activator 991; 5-[[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic acid. Grades: ≥98%. CAS No. 1219739-36-2. Molecular formula: C24H18ClN3O3. Mole weight: 431.87. BOC Sciences 10
Ex26 Ex26 (S1P1-IN-Ex26) is a potent and selective sphingosine 1-phosphate receptor 1 ( S1P 1 ) antagonist ( IC 50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P 1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1-IN-Ex26. CAS No. 1233332-37-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117213. MedChemExpress MCE
Ex 26 Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM) with > 3,000-fold selectivity over S1P2, S1P3, S1P4 and S1P5. It causes lymphocyte sequestration in peripheral lymph nodes, and upregulates S1P1 receptor expression. Synonyms: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1233332-37-0. Molecular formula: C28H28ClFN2O3. Mole weight: 494.98. BOC Sciences 9
EX 527 EX 527. Group: Biochemicals. Grades: Purified. CAS No. 49843-98-3. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
EX-527 EX-527 Inhibitor. Uses: Scientific use. Product Category: T6111. CAS No. 49843-98-3. TARGETMOL CHEMICALS

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