A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ee-CBP is a hevein-type antimicrobial peptide from bark of the spindle tree (Euonymus europaeus L.).
EED-226
EED-226 is a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor (IC50 = 23.4 nM when the substrate is H3K27me0 peptide and IC50 = 53.5 nM when the substrate is mononucleosom). EED-226 induces a conformational change via binding EED which invalidates PRC2 activity. PRC2 plays pivotal roles in transcriptional regulation. EED-226 has the potential to treat PRC2-dependent cancers, such as human lymphoma xenograft tumors. Synonyms: EED226; EED-226; EED 226. N-(2-furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine. Grades: 98%. CAS No. 2083627-02-3. Molecular formula: C17H15N5O3S. Mole weight: 369.4.
A metabolite of Diethylstilbestrol. Group: Biochemicals. Alternative Names: 3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
EEDQ
EEDQ is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: EEDQ. CAS No. 16357-59-8. Pack Sizes: 25 g. Product ID: HY-Y1191.
100g Pack Size. Group: Biochemicals, Building Blocks, Peptide Reagents. Formula: C14H17NO3. CAS No. 16357-59-8. Prepack ID 16764018-100g. Molecular Weight 247.29. See USA prepack pricing.
25g Pack Size. Group: Biochemicals, Building Blocks, Peptide Reagents. Formula: C14H17NO3. CAS No. 16357-59-8. Prepack ID 16764018-25g. Molecular Weight 247.29. See USA prepack pricing.
The eEF-2 Kinase Inhibitor, NH125, also referenced under CAS 278603-08-0, controls the biological activity of eEF-2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable pyrido-pyrimidinedione derivative that acts as a highly potent and selective inhibitor of eukaryotic elongation factor-2 kinase (eEF2K) (IC50=280nM). Exhibits very little activity against a broad panel of serine/threonine and protein tyrosine kinases. Inhibits eEF2 phosphorylation in multiple cell lines tested without affecting the net eEF2 levels. At concentration where it inhibits eEF2K activity, it has no effect on the proliferation of cancer cell lines.CAS No.142557-61-7. Group: Biochemicals. Grades: Highly Purified. CAS No. 142557-61-7. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 289.3. US Biological Life Sciences.
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eEF2K Inhibitor, A-484954 - CAS 142557-61-7
The eEF2K Inhibitor, A-484954, also referenced under CAS 142557-61-7, controls the biological activity of eEF2K Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
Eeyarestatin I
Eeyarestatin I. Group: Biochemicals. Grades: Purified. CAS No. 412960-54-4. Pack Sizes: 10mg. US Biological Life Sciences.
Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Eeyarestatin I suppresses ataxin-3 (atx3)-dependent deubiquitination targeting the p97-associated deubiquinating process (PAD). It also inhibits Sec61-mediated protein translocation at the ER. Eeyarestatin I exhibits cytotoxic activity against cancer cells. Synonyms: 3- (4-Chlorophenyl) -4-[[[ (4-chlorophenyl) amino]carbonyl]hydroxyamino]-5, 5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide. Grades: ≥98% by HPLC. CAS No. 412960-54-4. Molecular formula: C27H25Cl2N7O7. Mole weight: 630.44.
EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 152721-37-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00118.
Efalizumab
Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a , the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 214745-43-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9947.
Efaproxiral
Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSR13. CAS No. 131179-95-8. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-13619.
Efaproxiral
Allosteric modifier of hemoglobin (HB). Binds in the central water cavity of the Hb molecule causing a conformational change such that bound oxygen is released more readily. Antineoplastic adjunct (radiosensitizer). Group: Biochemicals. Alternative Names: 2-[4-[2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoic Acid; RSR 13. Grades: Highly Purified. CAS No. 131179-95-8. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Efaproxiral
synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. One use for efaproxiral is to increase the efficacy of certain chemotherapy drugs which have reduced efficacy against hypoxic tumours, and can thus be made more effective by increased offloading of oxygen into the tumour tissues. However, no benefit was seen for efaproxiral in phase III clinical trials. Synonyms: RSR13; RSR-13; RSR 13; Efaproxyn; NSC722758; (24 (35di methyl anilino) carbonyl methyl phenoxyl2 methyl proprionic acid sodium salt. CAS No. 131179-95-8. Molecular formula: C20H23NO4. Mole weight: 341.4.
Efaproxiral sodium
Efaproxiral sodium (RSR13 sodium) is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSR13 sodium. CAS No. 170787-99-2. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-13619A.
Efaproxiral Sodium
Efaproxiral, a synthetic allosteric modi?er of hemoglobinoxygen binding af?nity, has been shown to bind reversibly to hemoglobin, stabilizing the deoxyhemoglobin tetramer conformation to reduce its af?nity for oxygen. Synonyms: Efaproxiral sodium; 170787-99-2; RSR13 SODIUM; Sodium 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoate; Efaproxiral (sodium); Efaproxiral sodium [USAN]; RSR-13 SODIUM; 3L83QP52XI; 170787-99-2 (sodium); Efaproxyn; Efaproxiral sodium (USAN); Sodium 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoate; Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl-, monosodium salt; Efaproxiral Sodium. Grades: >98%. CAS No. 170787-99-2. Molecular formula: C20H23NO4.Na. Mole weight: 363.38.
Efaroxan hydrochloride
Efaroxan hydrochloride is a potent and selective α2 adrenoceptor antagonist and imidazoline I1 receptor ligand (pKi = 7.87, 7.42, 5.74, 7.28 and < 5 for α 2A, α2B, α2C, I1, and I2 receptors, respectively). Efaroxan promotes insulin secretion, at a site distinct from I1 or I2 (the putative I3 receptor) in vitro and in vivo. Synonyms: Efaroxan HCl; RX 821037A; RX821037A; RX-821037A; EU-0100521; EU0100521; EU 0100521; 2-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-4,5-dihydro-1H-imidazole hydrochloride. Grades: ≥99% by HPLC. CAS No. 89197-00-2. Molecular formula: C13H16N2O.HCl. Mole weight: 252.74.
Efaroxan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 89197-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Efavaleukin alfa
Efavaleukin alfa (AMG592) is a human monoclonal antibody. Efavaleukin alfa is composed of the IGHG1 Fc fragment fused to IL-2. The expression system of Efavaleukin alfa is usually CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG592. CAS No. 2049067-94-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99877.
Efavirenz
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a K i of 2.93 nM and exhibits an IC 95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DMP 266; EFV; L-743726. CAS No. 154598-52-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10572.
Efavirenz 1-Desamine
Efavirenz 1-Desamine is an analog of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Alternative Names: 7-Chloro-1- (cyclopropylethynyl) -1- (trifluoromethyl) isochroman-3-one. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C15H10ClF3O2. US Biological Life Sciences.
Worldwide
Efavirenz Benzoylaminoalcohol Impurity
An impurity arising in the synthesis of Efavirenz. Synonyms: rac N-[4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl]phenyl]-4-methoxybenzamide. Grades: > 95%. CAS No. 1189491-03-9. Molecular formula: C21H17ClF3NO3. Mole weight: 423.81.
Efavirenz impurity (6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) is an impurity of Efavirenz, a medication used to treat HIV/AIDS. Grades: > 95%. CAS No. 1217623-65-8. Molecular formula: C15H11ClF3NO2. Mole weight: 329.71.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsimpurity standardspharmaceutical toxicology. Alternative Names: Efavirenz Racemic, ((+/-)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one).
Efavirenz Ready Made Solution
10 mg/mL in DMSO. Group: Fluorescence/luminescence spectroscopy.
Efavirenz Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Efavirenz Related Compound A
Cas No. 209414-27-7.
Efavirenz Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Efavirenz Related Compound B
Efavirenz impurity. Synonyms: (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one; USP Efavirenz Related Compound B. Grades: > 95%. CAS No. 440124-96-9. Molecular formula: C14H11ClF3NO2. Mole weight: 317.69.
Efavirenz Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Efavirenz Related Compound C
An impurity of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent. Synonyms: 2-Cyclopropyl-6-chloro-4-(trifluoromethyl)quinoline, USP Efavirenz Related Compound C. Grades: > 95%. CAS No. 391860-73-4. Molecular formula: C13H9ClF3N. Mole weight: 271.67.
Efavirenz (Sustiva, MDP-266, L-743726)
A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266; L 743726; Stocrin; Sustiva. Grades: Highly Purified. CAS No. 154598-52-4. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C14H9ClF3NO2, Molecular Weight: 315.67. US Biological Life Sciences.
Worldwide
Efbemalenograstim alfa
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Benegrastim; Bineuta; F 627. CAS No. 2200269-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99879.
Effervellen impurity3
Effervellen impurity3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1132642-95-5. Molecular formula: C14H4D5ClF3NO2. Mole weight: 320.71. Catalog: APB1132642955.
Effusol
Effusol. Group: Biochemicals. Alternative Names: 5-Ethenyl-9,10-dihydro-1-methyl-2,7-phenanthrenediol; NSC 371300. Grades: Highly Purified. CAS No. 73166-28-6. Pack Sizes: 10mg. Molecular Formula: C17H16O2. US Biological Life Sciences.
Worldwide
EFIN
EFIN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9-Dimethyl-N,N-diphenyl-7-(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-9H-fluoren-2-amine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1705571-72-7. Molecular formula: C46H35N3. Mole weight: 629.79 g/mol. Product ID: ACM1705571727. Alfa Chemistry ISO 9001:2015 Certified. Categories: Efinaconazole.
Efinaconazole
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; Efinaconazole; trade name: Jublia. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39. Purity: >98%. IUPACName: (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. Canonical SMILES: C[C@@H](N1CCC(CC1)=C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3. Product ID: ACM164650446. Alfa Chemistry ISO 9001:2015 Certified.
Efinaconazole
Efinaconazole is a topical antifungal for onychomycosis. Group: Biochemicals. Alternative Names: (αR, βR)-α-(2,4-Difluorophenyl)- β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol; [R-(R*,R*)]-α-(2,4-Difluorophenyl)- β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol; KP 103; KP 103. Grades: Highly Purified. CAS No. 164650-44-6. Pack Sizes: 500mg, 1g. Molecular Formula: C??H??F?N?O, Molecular Weight: 348.39. US Biological Life Sciences.
Worldwide
Efinaconazole
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Synonyms: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia. Grades: >98%. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39.
Efinaconazole
Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively [1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KP-103. CAS No. 164650-44-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15660.
Efinaconazole
?98% (HPLC). Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolites. Alternative Names: (?R,?R)-?-(2,4-Difluorophenyl)-?-methyl-4-methylene-?-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 1-Piperidineethanol, ?-(2,4-difluorophenyl)-?-methyl-4-methylene-?-(1H-1,2,4-triazol-1-ylmethyl)-, [R-(R*,R*)]-, Efinaconazole, KP 103, Jublia,1-Piperidineethanol, ?-(2,4-difluorophenyl)-?-methyl-4-methylene-?-(1H-1,2,4-triazol-1-ylmethyl)-, (?R,?R)-, KP 103 (pharmaceutical).
Efinaconazole Impurity 30
Efinaconazole Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diyl dimethanesulfonate. CAS No. 153522-54-4. Molecular formula: C14H17F2N3O6S2. Mole weight: 425.43. Catalog: APB153522544.
Efinaconazole Impurity 44
Efinaconazole Impurity 44. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol. CAS No. 133775-25-4. Molecular formula: C12H13F2N3O2. Mole weight: 269.25. Catalog: APB133775254.
Efinaconazole Impurity 50
Efinaconazole Impurity 50. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133775-26-5. Molecular formula: C13H15F2N3O4S. Mole weight: 347.34. Catalog: APB133775265.
Efinaconazole Related Impurity 3
The S,S-enantiomer of Efinaconazole, a medication used to treat toenail infection caused by fungus. Synonyms: ent-Efinaconazole; (2S,3S)-Efinaconazole; (αS,βS)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol; [S-(R*,R*)]-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol. Grades: > 95%. CAS No. 164650-45-7. Molecular formula: C18H22F2N4O. Mole weight: 348.39.
The 2S,3R-enantiomer of Efinaconazole. Synonyms: 1-[[(2S,3S)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole; (2S-trans)-1-[[2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole. Grades: > 95%. CAS No. 135270-10-9. Molecular formula: C12H11F2N3O. Mole weight: 251.23.
Efinaconazole Related Impurity 6
The 2R,3S-enantiomer of Efinaconazole. Synonyms: 1-[[(2R,3R)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole; (2R-trans)-1-[[2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole. Grades: > 95%. CAS No. 135270-13-2. Molecular formula: C12H11F2N3O. Mole weight: 251.23.
Efinaconazole Related Impurity 7 Mesylate
A useful synthetic intermediate in the synthesis of Efinaconazole. Synonyms: (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Methanesulfonate. Grades: > 95%. CAS No. 1175536-50-1. Molecular formula: C12H13F2N3O2. CH4O3S. Mole weight: 365.35.
Efineptakin alfa
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NT-17. CAS No. 2026634-47-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99908.
Eflornithine
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO; MDL71782; RMI71782; α-difluoromethylornithine. CAS No. 70052-12-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744.
Eflornithine
Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grades: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17.
Eflornithine HCl
2-(Difluoromethyl)-DL-ornithine monohydrochloride. therapeutic for thrombocytopenia, effective against idiopathic thrombocytopenic purpura and cirrhosis due to hepatitis C . CAS No. 68278-23-9. Product ID: 8-04346. Molecular formula: C6H12F2N2O2.HCl. Mole weight: 218.63.
Eflornithine hydrochloride
Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; MDL 71782 hydrochloride; RMI 71782 hydrochloride; MDL-71782 hydrochloride; RMI-71782 hydrochloride; α-difluoromethylornithine hydrochloride; Vaniqa hydrochloride. Grades: >98%. CAS No. 68278-23-9. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63.
Eflornithine hydrochloride
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride. CAS No. 68278-23-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744A.
Eflornithine hydrochloride
Eflornithine hydrochloride. Group: Biochemicals. Alternative Names: DFMO; DL-2-(Difluoromethyl)-ornithine hydrochloride. Grades: Highly Purified. CAS No. 68278-23-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C6H12F2N2O2·HCl. US Biological Life Sciences.
Worldwide
Eflornithine hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.