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| Product | Description | |
|---|---|---|
| EGFR-IN-70 | EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC 50 values of 23.6 and 307.5 nM for EGFR LR/TM/CS and EGFR WT , respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2926716-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150611. |  |
| EGFR-IN-78 | EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, is a reversible inhibitor of EGFR C797S -TK, and also an inducer of apoptosis. EGFR-IN-78 shows anti-proliferative activity, inhibits EGFR phosphorylation and arrests cell cycle at G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042104-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-149889. | |
| EGFR-IN-8 | EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48. EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407957-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126320. | |
| EGFR-IN-86 | EGFR-IN-86 (compound 4i) is an EGFR inhibitor ( IC 50 : 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3055550-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149530. | |
| EGFR-IN-89 | EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC 50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413029-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-156284. | |
| EGFR-IN-95 | EGFR-IN-95 (compound 5j) is an 2,4-diaminonicotinamide derivative. EGFR-IN-95 has potent inhibitory activity against EGFR del19/T790M/C797S and L858R/T790M/C797S [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3027135-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-163094. | |
| EGFR Inhibitor | A cell-permeable and highly selective EGFR tyrosine kinase inhibitor with IC50 value in the nanomolar range. Inhibition of EGFR induces apoptosis of tumor cells by ownregulating antiapoptotic proteins such as survivin and upregulating proapoptotic proteins such as Bim. Uses: Antitumor agent. Synonyms: EGFR inhibitor; EGFR-inhibitor; EGFRinhibitor; Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide; N- (3- ( (6- ( (3- (Trifluoromethyl) phenyl) amino) pyrimidin-4-yl) amino) phenyl) cyclopropanecarboxamide; K00598a. Grades: 99%. CAS No. 879127-07-8. Molecular formula: C21H18F3N5O. Mole weight: 413.4. |  |
| EGFR kinase inhibitor 3 | EGFR kinase inhibitor 3 (compound 2) is a bivalent ATP-allosteric EGFR kinase inhibitor with IC 50 s of <10 nM, 1.5 nM, 0.059 nM, 0.064 nM for WT EGFR, EGFR-activating mutations L858R, L858R/T790M and L858R/T790M/C797S, respectively. EGFR kinase inhibitor 3 is a C-linked inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922402-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162299. | |
| EGFR mutant-IN-2 | EGFR mutant-IN-2 (Compound D51) is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFR L858R/T790M/C797S mutant with an IC 50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFR del19/T790M/C797S mutant with an IC 50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2770009-06-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155005. | |
| EGFR T790M/L858R-IN-8 | EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR , targeting mutant EGFR T790M/L858R with IC 50 of 56.8 μM. The anti-proliferative effect of EGFR T790M/L858R-IN-8 on cancer cell lines A549, A431, and NHI-H1975 is not significant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 333419-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164056. | |
| EGFR-TK-IN-4 | EGFR-TK-IN-4 (compound 10k) is a potent and selective EGFR-TK inhibitor. EGFR-TK-IN-4 can induce apoptosis. EGFR-TK-IN-4 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3053485-72-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-161927. | |
| Eggmanone | Eggmanone is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 = 72 nM) displaying >40-fold selectivity over PDE3, PDE10, and PDE11. Eggmanone acts via blocking hedgehog signaling through PDE antagonism, downstream of smoothened signaling. Synonyms: 5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one. Grades: ≥98% by HPLC. CAS No. 505068-32-6. Molecular formula: C20H20N2O2S3. Mole weight: 416.58. | |
| Egg oil | Egg oil is a natural oil, which consists primarily of cholesterol, lecithin and glycerides of the fatty acids. Egg oil exhibits activity in regulating the gut microbial dysbiosis, alleviating obesity, insulin resistance and inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 8001-17-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N12670. | |
| Egg PC (60%) | Egg PC (60%). Group: Others. L-α-phosphatidylcholine (Egg, Chicken-60%) (Total Egg Phosphatide Extract); Egg PC (60%). Cat No: PHOZ-245. |  |
| Egg phosphatidylglycerol | Egg phosphatidylglycerol. Synonyms: EPG. CAS No. 383907-64-0. Product ID: PE-0569. Molecular formula: C40H76NaO10P. Mole weight: 782.284. Category: Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0569; Egg phosphatidylglycerol; Emulsifier; C40H76NaO10P; 383907-64-0. UNII: NA. Chemical Name: 1, 2-Diacyl-sn-Glycero-3-Phospho-[1-rac-glycerol]. Grade: Pharmceutical Excipients. Administration route: Intravenous injection. Dosage Form: Intravenous injection. Stability and Storage Conditions: Soluble in chloroform, slightly soluble in ethanol, insoluble in water. This product should be dark, sealed, frozen transportation and storage, avoid storage with strong oxidizing substances. Proper use and preservation of the condition of quality can be guaranteed for three years. Phospholipids can be hydrolyzed in strong acid and base environments, so contact with strong acid or base media should be avoided except for strong oxidizing substances. Commonly used amount and the maximum amount: The maximum dosage of intravenous injection is 0.36mg. |  |
| Egg Phospholipids | Egg Phospholipids. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0429. Category: Dispersants; Emollient; emulsifying agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Egg Phospholipids; Dispersion Excipients; Dispersants; Emollient; emulsifying agent; 93685-90-6; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg yolk lecithin. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. | |
| Egg Powder (Fipronil) | Egg Powder (Fipronil). Uses: For analytical and research use. Group: Pesticides & metabolites. Catalog: APS007745. |  |
| Egg yolk lecithin | Lecithins vary greatly in their physical form, from viscous semiliquids to powders, depending upon the free fatty acid content. They may also vary in color from brown to light yellow, depending upon whether they are bleached or unbleached or on the degree of purity. When they are exposed to air, rapid oxidation occurs, also resulting in a dark yellow or brown color. Lecithins have practically no odor. Those derived from vegetable sources have a bland or nutlike taste, similar to that of soybean oil. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0112. Category: Emollient; Emulsifying Agents; Solubilizing Agents. Product Keywords: Humectants Excipients; Stabilizers; Emulsifier & Suspending Agents; ; PE-0112; Egg yolk lecithin; Emollient; Emulsifying Agents; Solubilizing Agents; ; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg Phospholipids. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. Stability and Storage Conditions: Lecithins decompose at extreme pH. They are also hygroscopic and subject to microbial degradation. When heated, lecithins oxidize, darken, and decompose. Temperatures of 160-180°C will cause degradatio | |
| Egg yolk phosphatidylcholines | Egg yolk phosphatidylcholines. Group: Biochemicals. CAS No. 93685-90-6. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| EGIS-8332 | EGIS-8332 potently decreased AMPA and quisqualate induced LDH release (IC50 = 5.2 ± 0.4 and 7.4 ± 1.3 μM, respectively) from the cells. The inhibition of the AMPA/kainate ion channels by EGIS-8332 is non-competitive, not use dependent, and depends neither on the closed/open state of the channel, nor the membrane potential. Synonyms: 7-acetyl-5-(4-aminophenyl)-8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-8-carbonitrile; EGIS-8332; EGIS 8332; EGIS8332. Grades: >98%. CAS No. 220725-87-1. Molecular formula: C20H18N4O3. Mole weight: 362.389. | |
| Eglin c(41-49) | Eglin c(41-49). Uses: Designed for use in research and industrial production. Additional or Alternative Names: EGLIN C (41-49);H-SER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR-OH;SER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR. Product Category: Heterocyclic Organic Compound. CAS No. 122299-11-0. Molecular formula: C48H78N12O15. Mole weight: 1063.2043. Purity: 0.96. IUPACName: (3S)-4-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,3-dihydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methy. Canonical SMILES: CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(C(C)C)NC(=O)C2CCCN2. Density: 1.44 g/cm³. Product ID: ACM122299110. Alfa Chemistry ISO 9001:2015 Certified. |  |
| EGLU | EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord. Synonyms: (2S)-α-Ethylglutamic acid; (2S)-2-amino-2-ethylpentanedioic acid. Grades: ≥95% by HPLC. CAS No. 170984-72-2. Molecular formula: C7H13NO4. Mole weight: 175.18. | |
| Egomaketone | Egomaketone. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59204-74-9. Molecular Formula: C10H12O2. Mole Weight: 164.2. Catalog: APB59204749. | |
| Egt1442 | Egt1442. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EGT1442;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol;Bexagliflozin. Product Category: Heterocyclic Organic Compound. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 0. Density: 1.41. Product ID: ACM1118567057. Alfa Chemistry ISO 9001:2015 Certified. | |
| EGT1442 | EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival of SHRSP rats. It attenuates blood glucose and HbA(1c) levels and prolongs the survival of stroke-prone rats in db/db mice. It showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients. It was developed by Theracos and in clinic phase 1 trials. Uses: Egt1442 showed favorable properties and could be beneficial to the management of type 2 diabetic patients. Synonyms: THR1442; THR-1442; THR 1442; EGT1442; EGT-1442; EGT 1442; Bexagliflozin; (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[[4-[2- (cyclopropyloxy) ethoxy]phenyl]methyl]phenyl]-D-glucitol; Bexagliflozin; THR1442; EGT0001442; EGT-1442; THR-1442; EGT-0001442; (2S, 4R, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol; (3R, 4R, 5S, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol. Grades: >98%. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 464.94. | |
| EGTA | EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (K d ) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca 2+ over Mg 2+ (Mg 2+ K d 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 67-42-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0861. | |
| EGTA | Chelating agent for the determination of calcium. Group: Biochemicals. Alternative Names: Ethyleneglycol-bis-(2 aminoethylether)-N,N.N,N-tetraacetic acid; Glycol ether diamine tetraacetic acid; Egtazic acid. Grades: Molecular Biology Grade. CAS No. 67-42-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C14H24N2O10, Molecular Weight: 380.35. US Biological Life Sciences. | Worldwide |
| EGTA | 25g Pack Size. Group: Biochemicals, Ligands. Formula: C14H24N2O10. CAS No. 67-42-5. Prepack ID 29346817-25g. Molecular Weight 380.35. See USA prepack pricing. |  |
| EGTA tetrasodium | EGTA tetrasodium. Group: Biochemicals. Alternative Names: Ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid tetrasodium salt. Grades: Highly Purified. CAS No. 13368-13-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C14H20N2O10·4Na. US Biological Life Sciences. | Worldwide |
| EH-IDTBR | EH-IDTBR. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Product ID: (5Z)-3-ethyl-2-sulfanylidene-5-[[4-[9, 9, 18, 18-tetrakis(2-ethylhexyl)-15-[7-[(Z)-(3-ethyl-4-oxo-2-sulfanylidene-1, 3-thiazolidin-5-ylidene)methyl]-2, 1, 3-benzothiadiazol-4-yl]-5, 14-dithiapentacyclo[10.6.0.03, 10.04, 8.013, 17]octadeca-1(12), 2, 4(8), 6, 10, 13(17), 15-heptaen-6-yl]-2, 1, 3-benzothiadiazol-7-yl]methylidene]-1, 3-thiazolidin-4-one. Molecular formula: 1326g/mol. Mole weight: C72H88N6O2S8. CCCCC (CC)CC1 (C2=CC3=C (C=C2C4=C1C=C (S4)C5=CC=C (C6=NSN=C56)C=C7C (=O)N (C (=S)S7)CC)C (C8=C3SC (=C8)C9=CC=C (C1=NSN=C91)C=C1C (=O)N (C (=S)S1)CC) (CC (CC)CCCC)CC (CC)CCCC)CC (CC)CCCC. InChI=1S/C72H88N6O2S8/c1-11-21-25-43 (15-5)39-71 (40-44 (16-6)26-22-12-2)53-35-52-54 (36-51 (53)65-55 (71)37-57 (83-65)49-31-29-47 (61-63 (49)75-87-73-61)33-59-67 (79)77 (19-9)69 (81)85-59)72 (41-45 (17-7)27-23-13-3, 42-46 (18-8)28-24-14-4)56-38-58 (84-66 (52)56)50-32-30-48 (62-64 (50)76-88-74-62)34-60-68 (80)78 (20-10)70 (82)86-60/h29-38, 43-46H, 11-28, 39-42H2, 1-10H3/b59-33-, 60-34-. HKJHYTKBDDVGRK-IOUDQCQMSA-N. |  |
| EHNA hydrochloride | EHNA hydrochloride is a selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM) and also an inhibitor of adenosine deaminase. EHNA inhibits spontaneous differentiation of human ESCs in feeder-free conditions and directed neuronal differentiation. Uses: Antiviral agents. Synonyms: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride. Grades: >98%. CAS No. 58337-38-5. Molecular formula: C14H23N5O.HCl. Mole weight: 313.83. | |
| EHNA hydrochloride | EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2) ( IC 50 =4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)( IC 50 :0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58337-38-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg. Product ID: HY-103160A. | |
| EHNA hydrochloride | EHNA hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 81408-49-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| EHNA Hydrochloride (NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride) | EHNA Hydrochloride (NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride). Group: Biochemicals. Alternative Names: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride. Grades: Highly Purified. CAS No. 58337-38-5. Pack Sizes: 25mg. Molecular Formula: C14 H23 N5, Molecular Weight: 313.8. US Biological Life Sciences. | Worldwide |
| EHop-016 | EHop-016 is a potent and selective Rac GTPase Rac1 and Rac3 inhibitor. EHop-016 inhibits Rac1 activity with an IC 50 of 1.1 μM in MDA-MB-435 cells. EHop-016 inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380432-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12810. | |
| EHop-016 | EHop-016 is a rac GTPase inhibitor that blocks the interaction of Rac with GEF Vav in metastatic human breast cancer cells. Synonyms: N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-morpholinopropyl)pyrimidine-2,4-diamine; N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine. Grades: 98%. CAS No. 1380432-32-5. Molecular formula: C25H30N6O. Mole weight: 430.5. | |
| Ehp-inhibitor-1 | Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Synonyms: 6-(3-methoxyphenyl)-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 861249-59-4. Molecular formula: C18H15N5O. Mole weight: 317.352. | |
| Ehp-inhibitor-2 | Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Synonyms: 3-(7-amino-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol. CAS No. 861249-77-6. Molecular formula: C17H13N5O. Mole weight: 303.325. | |
| EHT 1864 | EHT 1864 is an inhibitor of Rac family small GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The K d values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 also potently inhibits other Rac-dependent transformation processes, Tiam1- and Ras-mediated growth transformation. EHT 1864 prevents Aβ 40 and Aβ 42 production in vivo. EHT 1864 dependently suppresses the release of migrasomes from podocytes induced by LPS, PAN, or HG [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 754240-09-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16659. | |
| EHT 1864 | EHT 1864 is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. Synonyms: EHT 1864; EHT1864; EHT-1864. Grades: >98%. CAS No. 754240-09-0. Molecular formula: C25H29Cl2F3N2O4S. Mole weight: 581.47. | |
| EHT-6706 | EHT-6706 is a novel microtubule-disrupting agent that targets the colchicine-binding site to inhibit tubulin polymerization. At low nM concentrations, EHT 6706 exhibits highly potent antiproliferative activity on more than 60 human tumor cell lines, even those described as being drug resistant. EHT 6706 also shows strong efficacy as a vascular-disrupting agent, since it prevents endothelial cell tube formation and disrupts pre-established vessels, changes the permeability of endothelial cell monolayers and inhibits endothelial cell migration. Genome-wide transcriptomic analysis of EHT 6706 effects on human endothelial cells shows that the antiangiogenic activity elicits gene deregulations of antiangiogenic pathways. These findings indicate that EHT 6706 is a promising tubulin-binding compound with potentially broad clinical antitumor efficacy. Synonyms: EHT6706; EHT 6706; EHT-6706. CAS No. 1351592-10-3. Molecular formula: C21H24N2O4. Mole weight: 368.43. | |
| EHT-6706 dihydrochloride | EHT-6706 can target the colchicine-binding site to inhibit tubulin polymerization as a tubulin polymerisation inhibitor. It is under the development of Diaxonhit. EHT 6706 also is a vascular-disrupting agent. It can prevent endothelial cell tube formation and disrupt pre-established vessels, change the permeability of endothelial cell monolayers and inhibit endothelial cell migration. In Jul 2013, preclincal development for treatment of cancer was ongoing in the USA. Uses: Cancer. Synonyms: EHT-6706 dihydrochloride; EHT 6706 dihydrochloride; EHT6706 dihydrochloride; 7-ethoxy-4-(3,4,5-trimethoxybenzyl)isoquinolin-8-amine dihydrochloride. Grades: 98%. CAS No. 1351592-09-0. Molecular formula: C21H26Cl2N2O4. Mole weight: 441.35. | |
| Ehtyl Alcohol 200 Proof | Ehtyl Alcohol 200 Proof Alternative Name: Ethanol- 200 proof//Denatured Alcohol. Grade: 100%/200 proof. CAS Number: 64-17-5. |  Los Angeles, CA 90023 |
| EI1 | EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC 50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB-145943. CAS No. 1418308-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15573. | |
| EI1 | EI1 inhibits cellular H3K27 methylation and activates Ezh2 target gene p16 expression. Synonyms: EI1; ei-1; KB-145943; 6-cyano-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-pentan-3-ylindole-4-carboxamide; 6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide; 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide; 6-cyano-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-1-(pentan-3-yl)-1H-indole-4-carboxamide; 6-cyano-n-((1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-1-(1-ethylpropyl)-1h-indole-4-carboxamide; EI1; Ezh2 inhibitor; Ezh2 inhibitor; EI-1; EI 1; GTPL7013; SCHEMBL16197843; DTXSID101111134; BCP23699; EX-A2431; s7611; AKOS030526508; CCG-268533; CS-1654; SB19343; NCGC00351776-01; NCGC00351776-03; AC-36069; AS-55788; HY-15573; C72647; A911213; Q27077166. Grades: >98%. CAS No. 1418308-27-6. Molecular formula: C23H26N4O2. Mole weight: 390.48. | |
| EI-1507-1 | EI-1507-1 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.23 μmol/L. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| EI-1507-2 | EI-1507-2 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.42 μmol/L. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| EI-1511-3 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-3 inhibited recombinant human ICE with an IC50 of 0.09 μmol/L. Synonyms: (2E,4E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-7-methylocta-2,4-dienamide. Molecular formula: C27H30N2O7. Mole weight: 494.54. | |
| EI-1511-5 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-5 inhibited recombinant human ICE with an IC50 of 0.38 μmol/L. Synonyms: (2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| EI-1625-2 | It is produced by the strain of Streptomyces sp. E-1625. EI-1625-2 inhibited recombinant human ICE with an IC50 of 0.2 μmol/L. Synonyms: (2E)-N-[(1S,5R,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-4-methyloct-2-enamide. Molecular formula: C27H32N2O7. Mole weight: 496.55. | |
| EI-1941-1 | It is originally isolated from Farrowia sp. E-1941. EI-1941-1 inhibited recombinant human ICE with an IC50 of 0.086 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 2,3-Dihydroxy-5-propyl-1a,5,6,7a-tetrahydro-2H-oxireno[g]isochromen-7(3H)-one. CAS No. 189828-31-7. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| EI-1941-2 | It is originally isolated from Farrowia sp. E-1941. EI-1941-2 inhibited recombinant human ICE with an IC50 of 0.006 μmol/L. It also inhibits elastase and cathepsin. CAS No. 189828-32-8. Molecular formula: C12H14O5. Mole weight: 238.24. | |
| EI-2128-1 | EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus. Synonyms: (2E)-N-[(1R,3S,4'S,5R,5'R,7S)-5'-Hydroxy-6-oxodihydro-3'H-spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'-furan]-4'-yl]-4,6-dimethyl-2-dodecenamide. Molecular formula: C23H35NO6. Mole weight: 421.53. | |
| EI-2346 | EI-2346 is originally isolated from Streptomyces sp. E-2346. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 3.9 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 3,10-Dihydroxy-8-[5-hydroxy-4-(hydroxymethyl)-1,3-dioxan-2-yl]-3-methyl-1-propyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione. Molecular formula: C22H26O9. Mole weight: 434.44. | |
| Eicosafluorononane | Eicosafluorononane. Group: Biochemicals. Alternative Names: Perfluorononane. Grades: Highly Purified. CAS No. 375-96-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Eicosane 99% | Eicosane 99%. CAS No. 112-95-8. VIGON Item # 500981. Categories: Speciality Ingrdients Suppliers. |  America & Internationally |
| Eicosanedioic acid | Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis. Uses: Scientific research. Group: Natural products. CAS No. 2424-92-2. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W034595. | |
| Eicosanedioic acid dimethyl ester | Eicosanedioic acid dimethyl ester. Group: Plastic additives. Alternative Names: DIMETHYL ICOSANEDIOATE; DIMETHYL EICOSANEDIOATE; EICOSANEDIOIC ACID DIMETHYL ESTER; EICOSANEDIOIC ACID DIMETHYL ESTER 95+%; Icosanedioic acid dimethyl ester. CAS No. 42235-38-1. Product ID: dimethyl icosanedioate. Molecular formula: 370.57. Mole weight: C22< / sub>H42< / sub>O4< / sub>. COC(=O)CCCCCCCCCCCCCCCCCCC(=O)OC. PODMJVMUYCFFMK-UHFFFAOYSA-N. 96%. | |
| Eicosanoic acid | Liquid; OtherSolid;Solid. Group: Solubility enhancing reagents. Alternative Names: Arachidic acid. CAS No. 506-30-9. Product ID: icosanoic acid. Molecular formula: 312.53. Mole weight: C20H40O2. CCCCCCCCCCCCCCCCCCCC(=O)O. InChI= 1S / C20H40O2 / c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15- 16-17-18-19-20 (21) 22 / h2-19H2, 1H3, (H, 21, 22). VKOBVWXKNCXXDE-UHFFFAOYSA-N. 99%+. | |
| Eicosanol | Eicosanol. Group: Solubility enhancing reagents. Alternative Names: Arachidic alcohol. CAS No. 629-96-9. Product ID: icosan-1-ol. Molecular formula: 298.52. Mole weight: C20H42O. CCCCCCCCCCCCCCCCCCCCO. BTFJIXJJCSYFAL-UHFFFAOYSA-N. 99%+. | |
| Eicosapentaenoic acid | Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences. | Worldwide |
| Eicosapentaenoic Acid | Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grades: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46. | |
| Eicosapentaenoic Acid | Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA; Timnodonic acid. CAS No. 10417-94-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0660. | |
| Eicosapentaenoic Acid-d5 | Eicosapentaenoic Acid-d 5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: EPA-d5; Timnodonic acid-d5. CAS No. 1197205-73-4. Pack Sizes: 1 mg (1.63 mM * 2 mL in Ethanol). Product ID: HY-B0660S. | |
| Eicosapentaenoic acid ethyl ester | Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0747. | |
| Eicosapentaenoic Acid Ethyl Ester | Eicosapentaenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: EPA 90E; Incromega E 7010. Grades: Highly Purified. CAS No. 73310-10-8. Pack Sizes: 100mg. Molecular Formula: C22H34O2, Molecular Weight: 330.5. US Biological Life Sciences. | Worldwide |
| Eicosapentaenoic Acid Impurity1 | Eicosapentaenoic Acid Impurity1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-49-8. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827498. | |
| Eicosapentaenoic Acid Impurity10 | Eicosapentaenoic Acid Impurity10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123940-93-2. Molecular Formula: C22H36O2. Mole Weight: 332.53. Catalog: APB123940932. | |
| Eicosapentaenoic Acid Impurity11 | Eicosapentaenoic Acid Impurity11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2580285-53-4. Molecular Formula: C20H32O2. Mole Weight: 304.47. Catalog: APB2580285534. | |
| Eicosapentaenoic Acid Impurity12 | Eicosapentaenoic Acid Impurity12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H42O2. Mole Weight: 338.58. Catalog: APB12251. | |
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