American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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Eleutheroside E Quick inquiry Where to buy Suppliers range | Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities. Uses: Anti-inflammatory. Synonyms: Acanthoside D; Eleutheroside E. Grades: >98%. CAS No. 39432-56-9. Molecular formula: C34H46O18. Mole weight: 742.72. | |
Eleutheroside E1 Quick inquiry Where to buy Suppliers range | Eleutheroside E1. Group: Biobased Products. Alternative Names: (+)-Syringaresinol O-beta-D-glucoside. Grades: 98%. CAS No. 7374-79-0. Product ID: BBC7374790. Molecular formula: C28H36O13. Mole weight: 580.58. IUPAC Name: (2S,3R,4S,5S,6R)-2-[4-[(3S,3aR,6S,6aR)-3-(4-hydroxy-3,5-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Appearance: Powder. Density: 1.399±0.06 g/ml. SMILES: COC1=CC (=CC (=C1O)OC)[C@@H]2[C@H]3CO[C@@H] ([C@H]3CO2)C4=CC (=C (C (=C4)OC)O[C@H]5[C@@H] ([C@H] ([C@@H] ([C@H] (O5)CO)O)O)O)OC. | |
EL-HPE high performance electrolyte Quick inquiry Where to buy Suppliers range | EL-HPE high performance electrolyte. Group: Organic Solar Cell (OPV) Materials. | |
EL-HSE high stability electrolyte Quick inquiry Where to buy Suppliers range | EL-HSE high stability electrolyte. Group: Organic Solar Cell (OPV) Materials. | |
EL-HTE high temperature electrolyte Quick inquiry Where to buy Suppliers range | EL-HTE high temperature electrolyte. Group: Organic Solar Cell (OPV) Materials. | |
Eliglustat Quick inquiry Where to buy Suppliers range | Eliglustat is a glucosylceramide synthase inhibitor indicated for the long-term treatment of type 1 Gaucher disease in patients who are CYP2D6 extensive metabolizers, intermediate metabolizers , or poor metabolizers in treatment-naive and treatment-experi. Uses: Inhibits glucosylceramide synthase(gcs). Synonyms: Genz-99067; Genz 99067; Genz99067;N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide. Grades: ≥98%. CAS No. 491833-29-5. Molecular formula: C23H36N2O4. Mole weight: 404.55. | |
Eliglustat hemitartrate Quick inquiry Where to buy Suppliers range | Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Synonyms: Genz-112638; Genz 112638; Genz112638; Eliglustat tartrate; Bis(N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1- ylmethyl)ethyl)octanamide) (2R,3R)-2,3-dihydroxybutanedioate; Octanamide, N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1- pyrrolidinylmethyl)ethyl)-, (2R,3R)-2,3-dihydroxybutanedioate; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide (2R,3R)-2,3-dihydroxybutanedioic acid. Grades: >98%. CAS No. 928659-70-5. Molecular formula: C50H78N4O14. Mole weight: 959.17. | |
Eliglustat Tartrate Quick inquiry Where to buy Suppliers range | Eliglustat Tartrate. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS001621. Format: Neat. | |
Elinafide Quick inquiry Where to buy Suppliers range | Elinafide, an isoquinoline derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in anticancer studies. Synonyms: Elinafide; UNII-HL580335SI; Elinafide [INN]; 2- [2- [3- [2- (1, 3-dioxobenzo [de]isoquinolin-2-yl) ethylamino]propylamino]ethyl]benzo [de]isoquinoline-1, 3-dione; LU-79553. Grades: 98%. CAS No. 162706-37-8. Molecular formula: C31H28N4O4. Mole weight: 520.59. | |
Elinogrel Quick inquiry Where to buy Suppliers range | Elinogrel is a P2Y12 antagonist displaying antiplatelet activity. Synonyms: 5-Chloro-N-[[[4-[6-Fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide. Grades: ≥98% by HPLC. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.95. | |
Elinogrel Quick inquiry Where to buy Suppliers range | Elinogrel. Group: Biochemicals. Grades: Purified. CAS No. 936500-94-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Elintaal Quick inquiry Where to buy Suppliers range | Elintaal (Acetaldehyde Ethyl Linalyl Acetal). CAS No. 40910-49-4. VIGON Item # 503213. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
Eliprodil Quick inquiry Where to buy Suppliers range | Eliprodil. Group: Biochemicals. Grades: Purified. CAS No. 119431-25-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Eliprodil Quick inquiry Where to buy Suppliers range | Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Synonyms: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. Grades: 95%. CAS No. 119431-25-3. Molecular formula: C20H23ClFNO. Mole weight: 347.85. | |
Eliprodil (alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NMDA Antagonist IX) Quick inquiry Where to buy Suppliers range | A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. Group: Biochemicals. Grades: Highly Purified. CAS No. 119431-25-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Elisidepsin Quick inquiry Where to buy Suppliers range | Elisidepsin is a marine-derived, synthetic cyclic depsipeptide with potential antineoplastic activity. Elisidepsin is a derivative of a natural marine compound that belongs to a family of dehydro aminobutyric acid-containing peptides (kahalalides) isolated from the herbivorous marine mollusk Elysia rufescens. Although the primary mechanism of action has yet to be elucidated, this agent exhibits anti-proliferative activity in a wide variety of cancer cell types, including breast, colon, pancreas, lung, and prostate; it appears to induce oncolytic rather than apoptotic cell death. Synonyms: PM-02734; N-[(4S)-4-methylhexanoyl]-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-N-{(3S,6Z,9S,12R,15R,18R,19R)-9-benzyl-15-[(2S)-butan-2-yl]-6-ethylidene-3,12-diisopropyl-19-methyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclononadecan-18-yl}-D-alloisoleucinamide. CAS No. 681272-30-0. Molecular formula: C75H124N14O16. Mole weight: 1477.90. | |
Elizabethin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces elizabethii. It has antifungal activity. CAS No. 78361-81-6. Molecular formula: C35H58O12. Mole weight: 670.83. | |
Ellagic acid Quick inquiry Where to buy Suppliers range | 25g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C14H6O8. CAS No. 476-66-4. Prepack ID 23304412-25g. Molecular Weight 302.19. See USA prepack pricing. | |
Ellagic acid Quick inquiry Where to buy Suppliers range | Natural Compounds; Herbal Medicinal Products Standards; Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: reagents. CAS No. 476-66-4. | |
Ellagic acid Quick inquiry Where to buy Suppliers range | Ellagic acid. Uses: Used for research and manufacturing. Group: Cosmetic Ingredients. Alternative Names: 4,4?,5,5?,6,6?-Hexahydroxydiphenic acid 2,6,2?,6?-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase. CAS No. 476-66-4. Product ID: CDC10-0049. | |
Ellagic acid Quick inquiry Where to buy Suppliers range | Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992);Solid. Group: Biobased Products. Alternative Names: Eleagicacid. Grades: 98%. CAS No. 476-66-4. Product ID: BBC476664. Molecular formula: C14H6O8. Mole weight: 302.19. IUPAC Name: 6, 7, 13, 14-Tetrahydroxy-2, 9-dioxatetracyclo[6.6.2.04, 16.011, 15]hexadeca-1(15), 4, 6, 8(16), 11, 13-hexaene-3, 10-dione. Appearance: Solid. Density: 1.667 g/cm³. SMILES: C1=C2C3=C (C (=C1O)O)OC (=O)C4=CC (=C (C (=C43)OC2=O)O)O. | |
Ellagic acid Quick inquiry Where to buy Suppliers range | Ellagic acid - Product ID: NST-10-60. Category: Polyphenols. Alternative Names: Benzoaric acid ; 4,4',5,5',6,6'-Hexahydroxydiphenic acid. Purity: 98%. Test method: HPLC. CAS No. 476-66-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Grey to brown Powder. Molecular formula: C14H6O8. Mole weight: 302.2. Storage: +2 +8 °C. | |
Ellagicacid Quick inquiry Where to buy Suppliers range | Yellow-brown fluid fine powder. Group: Material of cosmetics. Alternative Names: 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone. Grades: 20%-90% (HPLC/UV). CAS No. 476-66-4. Molecular formula: C14H6O8. Mole weight: 302.19. | |
Ellagic Acid Quick inquiry Where to buy Suppliers range | Ellagic Acid is a phenol antioxidant found naturally in various fruits and vegetables. Ellagic Acid was shown to exhibit high levels of antiproliferative and antioxidant properties in studies, which suggests its potential health benefits following ellagic acid consumption. Group: Biochemicals. Alternative Names: Alizarin yellow; Alizarine Yellow; Benzoaric acid; C.I. 55005; C.I. 75270; Elagostasine; Eleagic acid; G 91006; Gallogen; Gallogen (astringent); LDN 0097519; Lagistase. Grades: Highly Purified. CAS No. 476-66-4. Pack Sizes: 25g. Molecular Formula: C??H?O?, Molecular Weight: 302.19. US Biological Life Sciences. | Worldwide |
Ellagic acid, 96% Quick inquiry Where to buy Suppliers range | Ellagic acid, 96%. Uses: Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992);Solid. Group: Monomers. CAS No. 476-66-4. IUPAC Name: 6, 7, 13, 14-tetrahydroxy-2, 9-dioxatetracyclo[6.6.2.04, 16.011, 15]hexadeca-1(15), 4, 6, 8(16), 11, 13-hexaene-3, 10-dione. Molecular Weight: 302.19g/mol. Molecular Formula: C14H6O8. SMILES: C1=C2C3=C (C (=C1O)O)OC (=O)C4=CC (=C (C (=C43)OC2=O)O)O. InChI: InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H. InChIKey: AFSDNFLWKVMVRB-UHFFFAOYSA-N. Melting Point: greater than 680 °F (NTP, 1992);Greater than 360?;>360 ?;>360?. Density: 1.667 at 64 °F (NTP, 1992). Solubility: less than 1 mg/mL at 70° F (NTP, 1992);Slightly soluble in alcohol or water;Slightly soluble in alcohol; soluble in alkalies, in pyridine. Practically insoluble in ether;In water, 1.96X10+5 mg/L at 25 ? (est). | |
Ellagic acid dihydrate Quick inquiry Where to buy Suppliers range | Ellagic acid dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 133039-73-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H6O8.2H2O, Molecular Weight: 338.223. US Biological Life Sciences. | Worldwide |
Ellagic Acid, Dihydrate - CAS 476-66-4 Quick inquiry Where to buy Suppliers range | Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: reagents. CAS No. 476-66-4. Pack Sizes: 500MG. | |
Ellipticine Quick inquiry Where to buy Suppliers range | Ellipticine. Group: Heterocyclic Organic Compound. Alternative Names: 5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;ELLIPTICINE;3-b)carbazole,5,11-dimethyl-6h-pyrido(;icig770;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG). CAS No. 519-23-3. Product ID: ACM519233. Molecular formula: C17H14N2. Mole weight: 246.31. Melting Point: 316-318°C. Density: 1.257±0.06 g/cm³ (20 ºC 760 Torr). | |
Ellipticine, 98% Quick inquiry Where to buy Suppliers range | Ellipticine, 98%. Group: Apoptosis. CAS No. 519-23-3. Pack Sizes: 5mg. ID EBT1070. | |
Ellipticine (NSC 71795) Quick inquiry Where to buy Suppliers range | Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in target tissues. Ellipticine has been shown to inhibit the proliferation of human breast adenocarcinoma MCF-7 cells, leukemia HL-60 and CCRF-CEM cells, neuroblastoma IMR-32, UKF-NB-3, and UKF-NB-4 cells, and U87MG glioblastoma cells with IC50 values ranging from 0.27-4.7uM. Group: Biochemicals. Alternative Names: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole, NSC 71795. Grades: Highly Purified. CAS No. 519-23-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14N2, Molecular Weight: 246.3. US Biological Life Sciences. | Worldwide |
Elliptinium acetate Quick inquiry Where to buy Suppliers range | Elliptinium acetate. Group: Heterocyclic Organic Compound. Alternative Names: elliptinium acetate;Elliptinium;2-Methyl-9-hydroxyellipticinium acetate;Ellipticine acetomethylate;N2-Methyl-9-hydroxyellipticinium acetate;6H-Pyrido[4,3-B]carbazolium, 9-hydroxy-2,5,11-trimethyl-acetate (salt);9-Hydroxy-2-methylellipticinium acetate;H9m2E. CAS No. 58337-35-2. Molecular formula: C20H20N2O3. Mole weight: 336.3844. | |
Elloramycin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces olivaceus Tu 2353. It has weak activity against gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity. Synonyms: Elloramycin A; methyl (6aR,7S,10aR)-3-[(6-deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy]-6a,7,12-trihydroxy-8,10a-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate; (6aR)-3-[(2-O,3-O,4-O-Trimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-6,6a,7,10,10a,11-hexahydro-6aα,7α,12-trihydroxy-8,10aα-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylic acid methyl ester. CAS No. 97218-42-3. Molecular formula: C32H36O15. Mole weight: 660.62. | |
Elmycin B ((1aR, 3S, 5bR, 11S, 11aR, 11bR)-10, 11, 11a-Trihydroxy-3-methyl-3, 4, 5b, 11, 11a, 11b-hexahydrotetrapheno[5, 6-b]oxirene-5, 6(1aH, 2H)-dion) Quick inquiry Where to buy Suppliers range | Antibiotic. Antibacterial. Moderate cytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 128233-09-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
ELN 441958 Quick inquiry Where to buy Suppliers range | ELN441958 is a novel, potent and selective bradykinin B1 receptor antagonist with Ki value of 0.26 nM. It competitively inhibited the binding of the agonist [3H]DAKD to the human B1 receptor in IMR-90 lung fibroblast cell membranes. It is highly selective for B1 over B2 receptors and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor. It also inhibited human μ-, δ-, κ- opioid receptors and muscarinic M1 receptor with Ki values of 0.13, 0.69, 1.5 and 0.37 μM, respectively. It exhibited good permeability and metabolic stability in vitro. It exhibited high oral bioavailability and moderate plasma half-lives in rats and rhesus monkeys. It does not inhibit the activation of the human bradykinin B2 receptor at concentrations up to 10 μM. It has a moderate clearance and volume of distribution in both species following i.v. administration, consistent with the high metabolic stability in rat, rhesus, and human microsomes. Uses: Eln441958 exhibited high oral bioavailability and moderate plasma half-lives. Synonyms: ELN441958; ELN 441958; ELN-441958;7-Chloro-2-[3-[[9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl]carbonyl]phenyl]-2,3-dihydroisoindol-1-one. Grades: >98%. CAS No. 913064-47-8. Molecular formula: C29H29ClN4O2. Mole weight: 501.02. | |
ELN 484228 Quick inquiry Where to buy Suppliers range | ELN 484228 is an α-Synuclein blocker with activity in cellular models of α-synuclein-mediated dysfunction such as Parkinson's Disease. Study showed that ELN484228 reduced synaptic levels of αSyn in neuronal cultures from both wild type rats and from transgenic mice overexpressing αSyn by not more than two-fold. Synonyms: ELN484228; ELN-484228; ELN 484228. N-(4-Fluorophenyl)benzenesulfonamide. Grades: 99%. CAS No. 312-63-0. Molecular formula: C12H10FNO2S. Mole weight: 251.28. | |
ELND006 Quick inquiry Where to buy Suppliers range | ELND006 is one of the newest molecules to be reported on regarding the testing of the β-amyloid hypothesis. ELND006 is a novel oral γ-secretase inhibitor. At the 2010 Alzheimer's Association International Conference on Alzheimer's Disease in which ELND006 was reported to have an in vitro IC50 = 0.34 nM against APP and IC50 = 5.3 nM versus Notch signaling. Synonyms: ELND006; ELND-006; ELND 006. (4R)-4-cyclopropyl-7,8-difluoro-5-[4-(trifluoromethyl)phenyl]sulfonyl-1,4-dihydropyrazolo[4,3-c]quinoline; UNII-7F5QGV49GL; ELND006; ELND-006; 959997-22-9; (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo(4,3-c)quinoline; (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline; 7F5QGV49GL; SCHEMBL486044; GTPL7337; CHEMBL2396778. CAS No. 1333990-84-3. Molecular formula: C20H14F5N3O2S. Mole weight: 455.07. | |
ELND007 Quick inquiry Where to buy Suppliers range | ELND007 is a γ-secretase inhibitor. Synonyms: ELND007; ELND-007; ELND 007. (R)-4-cyclopropyl-8-fluoro-5-((6-(trifluoromethyl)pyridin-3-yl)sulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline; ELND007; ELND-007; ELND 007. CAS No. 1444006-79-4. Molecular formula: C19H14F4N4O2S. Mole weight: 438.08. | |
Elobixibat Quick inquiry Where to buy Suppliers range | Elobixibat is a potent and selective IBAT inhibitor under development for the treatment of chronic constipation and irritable bowel syndrome with constipation. Uses: Sodium-bile acid cotransporter-inhibitor. Synonyms: AZD-7806; AZD 7806; AZD7806; A 3309; A3309; A-3309; AJG-533; (2R)-N-[2-[[3,3-Dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycylglycine. Grades: ≥95%. CAS No. 439087-18-0. Molecular formula: C36H45N3O7S2. Mole weight: 695.89. | |
Elocalcitol Quick inquiry Where to buy Suppliers range | Elocalcitol. Group: Heterocyclic Organic Compound. Alternative Names: ELOCALCITOL. CAS No. 199798-84-0. Molecular formula: C29H43FO2. Mole weight: 442.65. | |
Elomotecan Quick inquiry Where to buy Suppliers range | Elomotecan (BN-80927) belongs to a novel family of camptothecin analogs, the homocamptothecins, developed on the concept of topoisomerase I (Topo I) inhibition and characterized by a stable seven-membered beta-hydroxylactone ring. Preclinical data reported here show that BN80927 retains Topo I poisoning activity in cell-free assay (DNA relaxation) as well as in living cells, in which in vivo complexes of topoisomerase experiments and quantification of DNA-protein-complexes stabilization, have confirmed the higher potency of BN80927 as compared with the Topo I inhibitor SN38. In addition, BN80927 inhibits Topo II-mediated DNA relaxation in vitro but without cleavable-complex stabilization, thus indicating catalytic inhibition. Moreover, a Topo I-altered cell line (KBSTP2), resistant to SN38, remains sensitive to BN80927, suggesting that a part of the antiproliferative effects of BN80927 are mediated by a Topo I-independent pathway. This hypothesis is also supported by in vitro data showing an antiproliferative activity of BN80927 on a model of resistance related to the noncycling state of cells (G(0)-G(1) synchronized). In cell growth assays, BN80927 is a very potent antiproliferative agent as shown by IC(50) values consistently lower than those of SN38 in tumor cell lines as well as in their related drug-resistant lines. BN80927 shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Altogether, these data strongly support the clinical development of BN80927. Synonyms: BN-80927; BN80927; BN 80927; R-1559; R1559; R 1559; (R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-((4-methylpiperidin-1-yl)methyl)-4, 5-dihydrooxepino[3', 4':6, 7]indolizino[1, 2-b]quinoline-3, 15(1H, 13H)-dione. CAS No. 220998-10-7. Molecular formula: C29H32ClN3O4. Mole weight: 522.04. | |
Elomotecan HCl salt Quick inquiry Where to buy Suppliers range | Elomotecan, also referred to BN 80927 and R 1559, characterized by a stable seven-membered beta-hydroxylactone ring, is a DNA topoisomerase inhibitor. In vivo elomotecan shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Synonyms: 220997-99-9; 220998-10-7 (Elomotecan free base); (5R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-[(4-methylpiperidin-1-yl)methyl]-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione hydrochloride (1:1). Grades: >98%. CAS No. 220997-99-9. Molecular formula: C29H33Cl2N3O4. Mole weight: 558.5. | |
ELOVL1-IN-2 Quick inquiry Where to buy Suppliers range | ELOVL1-IN-2 is an inhibitor of ELOVL1 (elongation of very-long-chain-fatty acid 1). CAS No. 2761063-79-8. Molecular formula: C18H15FN2O. Mole weight: 294.3. | |
Elpetrigine Quick inquiry Where to buy Suppliers range | Elpetrigine, also known as GW 273293 and JZP-4, has a blocking effect on calcium channels and potassium channels which has been in clinical bipolar disorders and epilepsy. Synonyms: 3-(2,3,5-trichlorophenyl)pyrazine-2,6-diamine; GW273293; GW-273293; GW 273293; JZP-4; JZP 4; JZP4; Elpetrigine. Grades: >98%. CAS No. 212778-82-0. Molecular formula: C10H7Cl3N4. Mole weight: 289.54. | |
Elphodex Acidic Kit Quick inquiry Where to buy Suppliers range | Elphodex Acidic Kit. Group: Polysaccharide. | |
Elphodextrin Starter Kit Quick inquiry Where to buy Suppliers range | Elphodextrin Starter Kit. Group: Polysaccharide. | |
ELQ-300 Quick inquiry Where to buy Suppliers range | ELQ-300 is a potent and orally bioavailable antimalarial agent, and it is a novel inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (complex III in the electron transport chain). Synonyms: 6-chloro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one. Grades: ≥98%. CAS No. 1354745-52-0. Molecular formula: C24H17ClF3NO4. Mole weight: 475.84. | |
ELR510444 Quick inquiry Where to buy Suppliers range | ELR510444 is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30.9 nM in MDA-MB-231 cells, inhibited the rate and extent of purified tubulin assembly, and displaced colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site. ELR510444 is not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines, suggesting that it circumvents both clinically relevant mechanisms of drug resistance to this class of agents. ELR510444 also shows potent antitumor activity in the MDA-MB-231 xenograft model with at least a 2-fold therapeutic window. Synonyms: ELR510444; ELR-510444; ELR 510444. Grades: >98%. CAS No. 1233948-35-0. Molecular formula: C19H16N2O2S2. Mole weight: 368.47. | |
Elsamicin B Quick inquiry Where to buy Suppliers range | Elsamicin B is produced by the strain of Actinomycetes J904-21. It is an antitumor antibiotic in the Chartreusin group. Aminoglycogen-deficient Elsamicin B shows only minimal antitumor activity. Synonyms: 10-[(3-C-Methyl-6-deoxy-β-D-galactopyranosyl)oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl-; 6-Hydroxy-1-methyl-5,12-dioxo-5,12-dihydrobenzo[g][2]benzopyrano[5,4,3-cde][2]benzopyran-10-yl 6-deoxy-3-C-methylhexopyranoside. CAS No. 97068-31-0. Molecular formula: C26H22O10. Mole weight: 494.45. | |
Elsamitrucin Quick inquiry Where to buy Suppliers range | Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Synonyms: Elsamicin A. Grades: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63. | |
Elsibucol Quick inquiry Where to buy Suppliers range | Elsibucol, a metabolically stable derivative of probucol, inhibits atherosclerosis and preserves endothelial healing following arterial injury. In vitro, elsibucol reduces vascular smooth muscle cell proliferation without affecting cell viability. Synonyms: 4-[2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenoxy]butanoic acid; (4,2,6-di-tert-butyl-4-(1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl)-phenoxy-butyric acid); Elsibucol; AGI 1096; AGI1096; AGI-1096; Elsibucol; UNII-O7T92N1Y8T.elsibucol. Grades: >98%. CAS No. 216167-95-2. Molecular formula: C35H54O4S2. Mole weight: 602.94. | |
Elsinochrome A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grades: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. | |
Elsinochrome B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52. | |
Elsinochrome C Quick inquiry Where to buy Suppliers range | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54. | |
Elsinochrome D Quick inquiry Where to buy Suppliers range | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52. | |
Eltanexor Quick inquiry Where to buy Suppliers range | Eltanexor (KPT-8602) is an investigational second-generation SINE compound. Eltanexor acts as an orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20-211?nM in 10 AML lines after 3 days exposure. Synonyms: KPT-8602; ONO-7706; ATG-016. Grades: ≥98%. CAS No. 1642300-52-4. Molecular formula: C17H10F6N6O. Mole weight: 428.29. | |
Eltenac Quick inquiry Where to buy Suppliers range | A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid; Telzenac; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. CAS No. 72895-88-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Eltenac Quick inquiry Where to buy Suppliers range | Eltenac. Group: Heterocyclic Organic Compound. Alternative Names: Eltenac;3-Thiopheneacetic acid, 4-(2,6-dichlorophenyl)amino-;4-[(2,6-Dichlorophenyl)amino]thiophene-3-acetic acid;[4-(2,6-DichlorophenylaMino)thiophen-3-yl]acetic Acid;4-(2,6-Dichloroanilino)-3- thiopheneacetic Acid;4-[(2,6-Dichlorophenyl)aMino]-3-thiopheneacetic Acid;Telzenac. CAS No. 72895-88-6. Molecular formula: C12H9Cl2NO2S. Mole weight: 0. | |
Eltenac-13C,d3 Quick inquiry Where to buy Suppliers range | Labeled Eltenac. A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid-13C,d3; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid-13C,d3; Telzenac-13C,d3; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Eltoprazine Quick inquiry Where to buy Suppliers range | Eltoprazine belongs the phenylpiperazine class which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It is closely related to fluprazine and batoprazine, which are similarly acting drugs. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It was found to (synergistically) potentiate the antidyskinetic effect of amantadine. It has been shown to reduce 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine;DU-28853;DU28853. Grades: >98 %. CAS No. 98224-03-4. Molecular formula: C12H16N2O2. Mole weight: 220.27. | |
Eltoprazine hydrochloride Quick inquiry Where to buy Suppliers range | Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine hydrochloride has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, monohydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;DU-28853 hydrochloride;DU28853 hydrochloride. Grades: >98 %. CAS No. 98206-09-8. Molecular formula: C12H17N2O2Cl. Mole weight: 256.73. | |
Eltoprazine hydrochloride Quick inquiry Where to buy Suppliers range | Eltoprazine hydrochloride. Group: Biochemicals. Alternative Names: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride; DU 28853; DU 28893. Grades: Highly Purified. CAS No. 98206-09-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H17ClN2O2. US Biological Life Sciences. | Worldwide |
Eltrombopag Quick inquiry Where to buy Suppliers range | Eltrombopag. Group: Heterocyclic Organic Compound. Alternative Names: Eltrombopag;3-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid;(1,1-Biphenyl)-3-carboxylic acid, 3-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2-hydroxy-;Eltrombopag [inn];Promacta;Sb497115;Sb-497115;Unii-S56D65xj9g. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47. Melting Point: 242-244°C. Density: 1.33. | |
Eltrombopag Quick inquiry Where to buy Suppliers range | Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). Uses: Nonpeptide thrombopoietin receptor agonist. Synonyms: SB-497115-GR, SB497115. Grades: >98%. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47. | |
Eltrombopag Quick inquiry Where to buy Suppliers range | An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia. Group: Biochemicals. Alternative Names: 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB 497115. Grades: Highly Purified. CAS No. 496775-61-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Eltrombopag Acyl Glucuronide Quick inquiry Where to buy Suppliers range | ||
Eltrombopag Amide Quick inquiry Where to buy Suppliers range | Eltrombopag Amide is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: > 95%. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48. | |
Eltrombopag Amide Quick inquiry Where to buy Suppliers range | Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences. | Worldwide |
Eltrombopag Ethyl Ester Quick inquiry Where to buy Suppliers range | Eltrombopag Ethyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C27H26N4O4, Molecular Weight: 470.52. US Biological Life Sciences. | Worldwide |
Eltrombopag Glucuronide Quick inquiry Where to buy Suppliers range | Eltrombopag Glucuronide. Group: Biochemicals. Alternative Names: 1-[3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene-3-14C]hydrazinyl]-2'-hydroxy[1,1'-biphenyl]-3-carboxylate]- β-D-glucopyranuronic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C31H30N4O10, Molecular Weight: 618.59. US Biological Life Sciences. | Worldwide |
Eltrombopag Methyl Ester Quick inquiry Where to buy Suppliers range | Eltrombopag Methyl Ester is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 1246929-01-0. Molecular formula: C26H24N4O4. Mole weight: 456.49. |