A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor III
The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor IV - CAS 127373-66-4
The Elastase Inhibitor IV, also referenced under CAS 127373-66-4, controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor V (2-(2-Bromophenyl)-5-chloro-3,1-benzoxazin-4-one)
A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 = 29.5nM), likely by covalently modifying active site serine. Shown to inhibit elastase secretion (IC50 = 80.8nM), but not O2 - generation, in fLMP-stimulated primary human neutrophil cultures. Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1mg/kg, i.v.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Elastase, Porcine pancreas
Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.36; Pancreatopeptidase E. CAS No. 39445-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2974.
Elastase Substrate I, Colorimetric - CAS 70967-90-7
A specific chromogenic substrate for human neutrophil elastase. Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate IV, Colorimetric
A specific substrate for pancreatic elastase. Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate V, Fluorogenic - CAS 72252-90-5
Elastase Substrate V, Fluorogenic, CAS 72252-90-5, is a sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 μM). Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate VIII, Colorimetric - CAS 52299-14-6
Substrate for the spectrophotometric assay of elastase. Group: Fluorescence/luminescence spectroscopy.
Elastatinal
Elastatinal is a potent and irreversible inhibitor of pancreatic elastase. It is a much stronger inhibitor of pancreatic elastase than the leukocyte-derived enzyme. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands. Synonyms: (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxyethyl]-L-glutamamide. Grades: ≥ 95 %. CAS No. 51798-45-9. Molecular formula: C21H36N8O7. Mole weight: 512.56.
Elastin Protein, Hydrolyzed. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hydrolyzed animal elastin. Product Category: Promotional Products. CAS No. 100085-10-7. Purity: 0.9. Product ID: ACM100085107-1. Alfa Chemistry ISO 9001:2015 Certified.
Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A ( HCV NS5A ) inhibitor with EC 50 s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8742. CAS No. 1370468-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15789.
Elbasvir
Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis C virus and is currently under Phase II trail. Uses: Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis c virus and is currently under phase ii trail. Synonyms: Elbasvir; MK-8742; UNII-632L571YDK; 632L571YDK; MK8742; MK 8742. Grades: 98%. CAS No. 1370468-36-2. Molecular formula: C49H55N9O7. Mole weight: 882.02.
Elcatonin
Elcatonin is a calcitonin derivative used as an anti-parathyroid agent. Synonyms: Elcatonin Acetate. Grades: 98%. CAS No. 60731-46-6. Molecular formula: C148H244N42O47. Mole weight: 3363.82.
Elcatonin is a Calcitonin derivative which is transformed from eel ?s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis. Elcatonin synthetic is a single, non-glycosylated polypeptide chain containing 31aa. Group: Biochemicals. Grades: Highly Purified. CAS No. 60731-46-6. Pack Sizes: 200ug. US Biological Life Sciences.
Worldwide
Eldacimibe
Eldacimibe is a Sterol O-acyltransferase inhibitor originated by Wyeth. No development was reported for Atherosclerosis and Hypercholesterolaemia in USA. Uses: Atherosclerosis; hypercholesterolaemia. Synonyms: ACA 147; ANA 147; WAY 125147; WAY ACA 147; 1,3-Dioxane-4,6-dione, 5-(((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)amino)(((4-(2,2-dimethylpropyl)phenyl)-methyl)hexylamino)methylene-2,2-dimethyl. Grades: 98%. CAS No. 141993-70-6. Molecular formula: C39H58N2O5. Mole weight: 634.89.
Eldecalcitol
Eldecalcitol, a vitamin D analog, has strong effects to reduce calcium reabsorption into the body from bones, therefore increasing bone mineral density, and to increase calcium absorption in intestines. Synonyms: TASP0390325, TASP 0390325, TASP-0390325. Grades: >98%. CAS No. 104121-92-8. Molecular formula: C30H50O5. Mole weight: 490.72.
Eldecalcitol
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3. CAS No. 104121-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-A0020.
Eldecalcitol
Eldecalcitol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R,3R,Z)-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol. CAS No. 104121-92-8. Molecular formula: C30H50O5. Mole weight: 490.72. Catalog: APB104121928.
Eldecalcitol Intermediate A
Eldecalcitol Intermediate A is an intermediate of eldecalcitol, a vitamin D3 analogue for the treatment of osteoporosis. Eldecalcitol is more active in bone resorption inhibition in comparison with alfacalcidol. Synonyms: 3-[(1R,2R,4Z,6R)-2,6-bis[[tert-butyl(dimethyl)silyl]oxy]-4-(2-diphenylphosphorylethylidene)-3-methylidenecyclohexyl]oxypropoxy-tert-butyl-dimethylsilane. CAS No. 200636-54-0. Molecular formula: C42H71O5PSi3. Mole weight: 771.254.
Eldelumab is a humanized anti-CXCL10 (IP-10) monoclonal antibody that binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab has been use for the treatment of ulcerative colitis. Synonyms: BMS-936557; MDX-1100. CAS No. 946414-98-8.
Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart's electrical cycle) in patients with long QT-3 (LQT3) syndrome. Phase III clinical trilas for the treatment of Long QT syndrome, Phase II/III clinical trilas for the treatment of Hypertrophic cardiomyopathy and Phase II clinical trilas for the treatment of Ventricular arrhythmias are on-going. Uses: Long qt syndrome;hypertrophic cardiomyopathy;ventricular arrhythmias. Synonyms: GS-6615; GS 6615; GS6615; Eleclazine. 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]- 3,4-dihydro-1,4-benzoxazepin-5(2H)-one. Grades: 98%. CAS No. 1443211-72-0. Molecular formula: C21H16F3N3O3. Mole weight: 415.37.
Eleclazine HCl
Eleclazine HCl is a novel late Na+ current inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eleclazine Hydrochloride; Eleclazine HCl; GS-6615; GS 6615; GS6615. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1448754-43-5. Molecular formula: C21H17ClF3N3O3. Mole weight: 451.83. Purity: >98%. IUPACName: 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one hydrochloride. Canonical SMILES: O=C1N(CC2=NC=CC=N2)CCOC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C13.[H]Cl. Product ID: ACM1448754435. Alfa Chemistry ISO 9001:2015 Certified.
Eleclazine hydrochloride
Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC 50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 6615 hydrochloride. CAS No. 1448754-43-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16738A.
Electreoless NICKEL SULPHATE
Electreoless NICKEL SULPHATE. CAS No. 10101-98-1. Molecular Formula NiSO4 * 6H2O. Electroless Electroplating Chemicals
Cater Chemicals Corp. Illinois IL
Electrical Conductivity Carbon Nanotubes (SWCNTs)
Electrical Conductivity Carbon Nanotubes (SWCNTs). Group: Single wall cnt. CAS No. 308068-56-6. >98% (SWNT) Electric current density >10-2S/cm.
Electric Heating Reduce Graphene Oxide Powder
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, O
Electrode pole pieces
Electrode pole pieces. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-167. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane.
Electrolytic Copper with added Impurities. Uses: For analytical and research use. Group: Physical properties; metal alloys; physical properties. Catalog: APS007775. Format: Neat. Shipping: Room Temperature.
Electronic Magnet Pole Identifier
Electronic Magnet Pole Identifier. Group: Magnetic nanoparticles.
electron-transferring-flavoprotein dehydrogenase
An iron-sulfur flavoprotein, forming part of the mitochondrial electron-transfer system. Group: Enzymes. Synonyms: ETF-QO; ETF:ubiquinone oxidoreductase; electron transfer flavoprotein dehydrogenase; electron transfer flavoprotein Q oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; electron transfer flavoprotein reductase. Enzyme Commission Number: EC 1.5.5.1. CAS No. 86551-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1556; electron-transferring-flavoprotein dehydrogenase; EC 1.5.5.1; 86551-03-3; ETF-QO; ETF:ubiquinone oxidoreductase; electron transfer flavoprotein dehydrogenase; electron transfer flavoprotein Q oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; electron transfer flavoprotein reductase. Cat No: EXWM-1556.
Eledoisin
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors. Uses: Scientific research. Group: Peptides. Alternative Names: Eledone peptide. CAS No. 69-25-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0006.
Eledoisin
Eledoisin is an undecapeptide of mollusk origin and it belongs to the tachykinin family of neuropeptides. It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi. Eledoisin has the amino acid sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2. It is the Potent natural tachykinin receptor ligand. Uses: Neurotransmitter agents. Synonyms: Eledone peptide; Eledoisinum; 5-oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-α-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide. Grades: >98%. CAS No. 69-25-0. Molecular formula: C54H85N13O15S. Mole weight: 1188.41.
Eledoisin
Eledoisin. Group: Biochemicals. Grades: Purified. CAS No. 69-25-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Eledoisin Related Peptide
Eledoisin-Related Peptide, a substance P analogue, is a tachykinin receptor ligand. Synonyms: Eledoisin-Related Peptide; Eledoisin RP; H-Lys-Phe-Ile-Gly-Leu-Met-NH2; L-lysyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide; (S)-2,6-diamino-N-((5S,8S,14S,17S)-14-sec-butyl-5-carbamoyl-8-isobutyl-7,10,13,16-tetraoxo-18-phenyl-2-thia-6,9,12,15-tetraazaoctadecan-17-yl)hexanamide; Lpiglm. Grades: ≥95%. CAS No. 2990-43-4. Molecular formula: C34H58N8O6S. Mole weight: 706.94.
Eledoisin-Related Peptide
Eledoisin-Related Peptide. Group: Biochemicals. Grades: Purified. CAS No. 2990-43-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Eledoisin Related Peptide 2TFA
Eledoisin Related Peptide 2TFA, a substance P analogue, is a tachykinin receptor ligand. Synonyms: H-Lys-Phe-Ile-Gly-Leu-Met-NH2.2TFA; L-lysyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid. Grades: ≥95%. CAS No. 2918768-25-7. Molecular formula: C34H58N8O6S.2C2HF3O2. Mole weight: 934.99.
Eledoisin trifluoroacetate
Eledoisin was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi. It is a potent natural tachykinin receptor ligand, and a potent vasodilator that increases capillary permeability. Synonyms: H-Pyr-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.TFA; L-pyroglutamyl-L-prolyl-L-seryl-L-lysyl-L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid; Eledoisin, mono(trifluoroacetate) (salt); 5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide trifluoroacetate; Eledoisin, trifluoroacetate (1:1). Grades: ≥95%. CAS No. 10129-92-7. Molecular formula: C54H85N13O15S.C2HF3O2. Mole weight: 1302.42.
Elemene Liposome
Elemene is a mixture of sesquiterpene alkenes, dominated by β-elemene, with broad-spectrum antitumor effects. This product is a pre-formulated liposome with elemene. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Elemicin is a alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin is one of the main components in aromatic food and has antimicrobial, antioxidant, and antiviral activities. Elemicin possesses genotoxicity and carcinogenicity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2,3-TRIMETHOXY-5-(2-PROPENYL)BENZENE;5-ALLYL-1,2,3-TRIMETHOXYBENZENE;ELEMICIN;1,2,3-trimethoxy-5-(2-propenyl)-benzen;1,2,3-trimethoxy-5-allylbenzene (elemicin);3,4,5-Trimethoxyallylbenzene;4-allyl-1,2,6-trimethoxybenzene;5-allyl-1,2,3-trimethoxy-benzen. Product Category: Inhibitors. Appearance: Oil. CAS No. 487-11-6. Molecular formula: C12H16O3. Mole weight: 208.3. Purity: 0.98. IUPACName: 1,2,3-trimethoxy-5-prop-2-enylbenzene. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)CC=C. Density: 1.011 g/cm³. Product ID: ACM487116. Alfa Chemistry ISO 9001:2015 Certified.
Elemicin
Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial , antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1-Hydroxyelemicin can induce hepatotoxicity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 487-11-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N6807.
Elemicin
A constituent of the essential oil of nutmeg and is responsible for the psychoactive effects of nutmeg. Also a minor constituent of the oleoresin and essential oil of Manila elemi (Canarium luzonicum). Exhibits anticholinergic-like effects in humans. Group: Biochemicals. Alternative Names: 1,2,3-Trimethoxy-5-(2-propen-1-yl)-benzene; 5-Allyl-1,2,3-trimethoxybenzene; 1-(3,4,5-Trimethoxyphenyl)-2-propene; 3, 4, 5-Trimethoxyallyl Benzene ; 5-(Prop-2-enyl)-1,2,3-trimethoxybenzene; 5-Allyl-1,2,3-trimethoxybenzene. Grades: Highly Purified. CAS No. 487-11-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Elenbecestat
Elenbecestat (E2609) is a potent, orally bioavailable and CNS-penetrant BACE-1 inhibitor. Elenbecestat has the potential for Alzheimer's disease (AD) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2609. CAS No. 1388651-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109055.
Elenbecestat
Elenbecestat is a novel, potent and orally bioavailable BACE1 inhibitor for the treatment of Alzheimer's disease (AD), which demonstrates prolonged reductions in plasma beta-amyloid levels after single dosing. Synonyms: E2609; N-[3-[(4aS,5R,7aS)-2-amino-5-methyl-4,4a,5,7-tetrahydrofuro[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-(difluoromethyl)pyrazine-2-carboxamide. Grades: ≥98%. CAS No. 1388651-30-6. Molecular formula: C19H18F3N5O2S. Mole weight: 437.44.
Elenestinib
Elenestinib is a next-generation KIT D816V inhibitor. Elenestinib exhibits potent inhibition of KIT D816V and an evolved pre-clinical profile with limited central nervous system penetration. Synonyms: BLU-263. CAS No. 2505078-08-8. Molecular formula: C27H29FN10O. Mole weight: 528.6.
Elenestinib
Elenestinib (BLU-263) is an orally active inhibitor of Tyrosine kinase with an IC 50 value of 6 nM for KIT D816V. Elenestinib minimally penetrates the blood-brain barrier. Elenestinib can be used in the study of systemic mastocytosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-263. CAS No. 2505078-08-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152839.
Elesclomol
Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp. Synonyms: STA4783; STA-4783; STA 4783, Elesclomol. CAS No. 488832-69-5. Molecular formula: C19H20N4O2S2. Mole weight: 400.52.
Eletriptan
Eletriptan is Serotonin 1D receptor agonist originated by Pfizer. It is a second generation triptan drug. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan was approved by the FDA for the acute treatment of migraine with or without aura in adults in 2002. Uses: Menstrual migraine; migraine. Synonyms: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole; (R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole; Eletriptan; UK 116044; UK-116,044; UK-116,044-04 [as hydrobromide]; UNII-22QOO9B8KI; Relpax free amine. Grades: 98%. CAS No. 143322-58-1. Molecular formula: C22H26N2O2S. Mole weight: 382.52.
Eletriptan induces concentration-dependent contractions of meningeal artery, coronary artery, and saphenous vein. The potency of Eletriptan is higher in meningeal artery than in coronary artery (86-fold) or saphenous vein (66-fold). Synonyms: Eletriptan Hydrobromide; CHEBI:61176; M41W832TA3; UNII-M41W832TA3; eletriptan hydrobromide; Relpax; UK 166,044; UK 166044; UK-166,044; UK-166044. Grades: >98%. CAS No. 177834-92-3. Molecular formula: C22H26N2O2S.HBr. Mole weight: 463.43.