A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Elacridar. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. Appearance: Solid. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.6. Purity: 0.98. Product ID: ACM143664113. Alfa Chemistry ISO 9001:2015 Certified.
Elacridar
Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences.
Worldwide
Elacridar-d4 (Major)
A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport. Group: Biochemicals. Alternative Names: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl-d4]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918-d4; GG 918-d4; GW 0918-d4. Grades: Highly Purified. CAS No. 1189481-51-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Elacridar hydrochloride
Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Synonyms: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10.
Elacridar hydrochloride
Elacridar hydrochloride (GF120918A) is an orally active P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar hydrochloride can be used to examine the influence of efflux transporters on agent distribution to brain and it can be used for the research of cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GF120918A. CAS No. 143851-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50880.
P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Elacytarabine
Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Synonyms: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67.
Elacytarabine
Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 4055. CAS No. 188181-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14941.
Elafibranor
Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Synonyms: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E) -1-[4- (Methylthio) phenyl]-3-[3, 5-dimethyl-4-[ (carboxydimethylmethyl) oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49.
Elafibranor
Elafibranor (GFT505) is a PPARα/δ agonist with EC 50 s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16737.
Elafin human
>90% (by MS, HPLC and SDS-PAGE), recombinant, expressed in Saccharomyces cerevisiae. Group: Fluorescence/luminescence spectroscopy.
Elagolix
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Synonyms: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6.
Elagolix Impurity 26
Elagolix Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092070-97-7. Molecular formula: C33H32F5N3O5. Mole weight: 645.63. Catalog: APB1092070977.
Elagolix sodium
Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Synonyms: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate;NBI56418 Na; NBI-56418; NBI 56418;834153-87-6 (Elagolix). Grades: 98%. CAS No. 832720-36-2. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58.
Elagolix sodium
Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-56418 sodium. CAS No. 832720-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14369.
Elaidamide
Elaidamide has been found in the cerebrospinal fluid of sleep-deprived cats. Elaidamide is a fatty acid amide that inhibits rat microsomal epoxide hydrolase (mEH; Ki = 70 nM) and porcine pancreatic and human synovial phospholipase A2 (PLA2). Uses: Food additives. Synonyms: Elaidoylamide; (E)-9,10-Octadecenamide; 9E-octadecenamide. Grades: ≥95%. CAS No. 4303-70-2. Molecular formula: C18H35NO. Mole weight: 281.5.
Elaidic acid
Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. Uses: Scientific research. Group: Natural products. CAS No. 112-79-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-113016.
Elaidic acid methyl ester
Elaidic acid methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elaidic acid methyl ester;trans-9-Octadecenoic methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 2462-84-2. Molecular formula: C19H36O2. Mole weight: 296.49. Density: 0.871 g/mL at 20 °C(lit.). Product ID: ACM2462842. Alfa Chemistry ISO 9001:2015 Certified. Categories: METHYL ELAIDATE.
It is produced by the strain of Streptomyces hepaticus. It has the activity of anti-gram-positive bacteria and negative bacteria, especially has strong effect on mycobacterium tuberculosis. It is a carcinogen. Synonyms: D-threo-4-Methoxy-3-(1-octenylazoxy)-2-butanol; D-threo-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; (2S,3S)-4-Methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, D-threo-; (E,Z)-(2S,3S)-4-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, (E,Z)-(2S,3S)-. CAS No. 23315-05-1. Molecular formula: C13H26N2O3. Mole weight: 258.36.
Elaiophylin
It is produced by the strain of Streptomyces melanosporofacien. It has the activity of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as insect repellent and growth promoter for ruminants. Elaiophylin is an autophagy inhibitor, which exerts antitumor activity as a single agent in ovarian cancer cells. Synonyms: Azalomycin B; Salbomycin; Azalomycin B; Antibiotic 5001B; Antibiotic 56-62; Elaiofilin. Grades: ≥95%. CAS No. 37318-06-2. Molecular formula: C54H88O18. Mole weight: 1025.26.
Antibiotic. Active against Gram-positive bacteria, protozoa and tumors. Testosterone 5alpha-reductase inhibitor. Nitric oxide synthase (NOS) inhibitor. Immunosuppressive and enhances the antifungal activity of rapamycin. Group: Biochemicals. Grades: Highly Purified. CAS No. 37318-06-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Elaiophyllin (Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846 I, Antibiotic SNA 4606-3, Azalomycin B, Gopalamicin, Salbomycin)
Elaiophyllin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophyllin inhibits testosterone 5-reductase. It has synergistic antifungal activity with its co-metabolite rapamycin. It has also been found to have anthelminthic and immunosuppressive activity and to inhibit nitric oxide synthesis. Elaiophyllin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumor cells. Group: Biochemicals. Alternative Names: Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846 I, Antibiotic SNA 4606-3, Azalomycin B, Gopalamicin, Salbomycin. Grades: Highly Purified. CAS No. 37318-06-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Elamipretide
Elamipretide (MTP-131) is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: MTP-131; RX-31; SS-31. CAS No. 736992-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0125.
Elamipretide triacetate
Elamipretide triacetate is an aromatic-cationic tetrapeptide that targets the mitochondrial intima and is an inhibitor of cardiolipin peroxidase. It easily penetrates cell membranes and has been used in therapeutic trials investigating Leber's Hereditary Optic Neuropathy. Synonyms: L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-, acetate (1:3); SS-31 triacetate; H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2.3CH3CO2H; D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide acetic acid; D-Arg-2',6'-Dmt-Lys-Phe-NH2 triacetate. Grades: ≥95%. CAS No. 1849610-71-4. Molecular formula: C32H49N9O5.3C2H4O2. Mole weight: 819.95.
Elasnin
Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Synonyms: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,?5-Dibutyl-6-(1-butyl-2-oxoheptyl)?-4-hydroxy-2H-pyran-2-one. Grades: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57.
Inhibitor of human leukocyte elastase (IC50=1.3ug/ml), different other elastases and chymotrypsin (IC50=82ug/ml). Group: Biochemicals. Grades: Highly Purified. CAS No. 68112-21-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Elastase
Elastase. Synonyms: EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;Elastase, pancreatic from porcine pancreas, 30 units/mg;Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free. CAS No. 39445-21-1. Pack Sizes: 1 g. Product ID: CDF4-0039. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; Elastase; CDF4-0039; 39445-21-1; 254-453-6; 39445-21-1. Purity: 0.99. Color: White. EC Number: 254-453-6. Physical State: Lyophilized Powder. Solubility: H2O: soluble. Storage: -20°C.
Elastase, Human leukocytes
Elastase, Human leukocytes is a serine protease present in the nitrogen-loving granules of neutrophils. Elastase, Human leukocytes potential substrates include almost all components of the extracellular matrix, as well as a variety of proteins such as coagulation factors, complement, immunoglobulins and cytokines. It has a strong proteolytic function and participates in the pathogenesis of inflammatory tissue damage [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9004-6-2. Pack Sizes: 1 U. Product ID: HY-P2751.
Elastase, Human Neutrophil
Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor II
The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor III
The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor IV - CAS 127373-66-4
The Elastase Inhibitor IV, also referenced under CAS 127373-66-4, controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
Elastase Inhibitor V (2-(2-Bromophenyl)-5-chloro-3,1-benzoxazin-4-one)
A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 = 29.5nM), likely by covalently modifying active site serine. Shown to inhibit elastase secretion (IC50 = 80.8nM), but not O2 - generation, in fLMP-stimulated primary human neutrophil cultures. Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1mg/kg, i.v.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Elastase, Porcine pancreas
Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.36; Pancreatopeptidase E. CAS No. 39445-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2974.
Elastase Substrate I, Colorimetric - CAS 70967-90-7
A specific chromogenic substrate for human neutrophil elastase. Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate IV, Colorimetric
A specific substrate for pancreatic elastase. Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate V, Fluorogenic - CAS 72252-90-5
Elastase Substrate V, Fluorogenic, CAS 72252-90-5, is a sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 μM). Group: Fluorescence/luminescence spectroscopy.
Elastase Substrate VIII, Colorimetric - CAS 52299-14-6
Substrate for the spectrophotometric assay of elastase. Group: Fluorescence/luminescence spectroscopy.
Elastatinal
Elastatinal is a potent and irreversible inhibitor of pancreatic elastase. It is a much stronger inhibitor of pancreatic elastase than the leukocyte-derived enzyme. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands. Synonyms: (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxyethyl]-L-glutamamide. Grades: ≥ 95 %. CAS No. 51798-45-9. Molecular formula: C21H36N8O7. Mole weight: 512.56.
Elastin Methacrylated (ElaMA) elastin recruits and modulates innate immune cells and accelerates angiogenesis at the wound site, thereby improving wound regeneration. Elastin Methacrylated attracts large numbers of neutrophils and primarily M2 macrophages to the wound and induces their penetration into the hydrogel. Elastin Methacrylated has excellent immunomodulatory effects, leading to superior angiogenesis, collagen deposition and dermal regeneration[1]. Elastin Methacrylated needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ElaMA. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158226.
Elastin Protein, Hydrolyzed. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hydrolyzed animal elastin. Product Category: Promotional Products. CAS No. 100085-10-7. Purity: 0.9. Product ID: ACM100085107-1. Alfa Chemistry ISO 9001:2015 Certified.
Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A ( HCV NS5A ) inhibitor with EC 50 s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8742. CAS No. 1370468-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15789.
Elbasvir
Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis C virus and is currently under Phase II trail. Uses: Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis c virus and is currently under phase ii trail. Synonyms: Elbasvir; MK-8742; UNII-632L571YDK; 632L571YDK; MK8742; MK 8742. Grades: 98%. CAS No. 1370468-36-2. Molecular formula: C49H55N9O7. Mole weight: 882.02.
Elcatonin
Elcatonin is a calcitonin derivative used as an anti-parathyroid agent. Synonyms: Elcatonin Acetate. Grades: 98%. CAS No. 60731-46-6. Molecular formula: C148H244N42O47. Mole weight: 3363.82.
Elcatonin is a Calcitonin derivative which is transformed from eel ?s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis. Elcatonin synthetic is a single, non-glycosylated polypeptide chain containing 31aa. Group: Biochemicals. Grades: Highly Purified. CAS No. 60731-46-6. Pack Sizes: 200ug. US Biological Life Sciences.
Worldwide
Elcubragistat
Elcubragistat (ABX-1431) is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABX-1431. CAS No. 1446817-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117632.
Eldacimibe
Eldacimibe is a Sterol O-acyltransferase inhibitor originated by Wyeth. No development was reported for Atherosclerosis and Hypercholesterolaemia in USA. Uses: Atherosclerosis; hypercholesterolaemia. Synonyms: ACA 147; ANA 147; WAY 125147; WAY ACA 147; 1,3-Dioxane-4,6-dione, 5-(((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)amino)(((4-(2,2-dimethylpropyl)phenyl)-methyl)hexylamino)methylene-2,2-dimethyl. Grades: 98%. CAS No. 141993-70-6. Molecular formula: C39H58N2O5. Mole weight: 634.89.
Eldecalcitol
Eldecalcitol, a vitamin D analog, has strong effects to reduce calcium reabsorption into the body from bones, therefore increasing bone mineral density, and to increase calcium absorption in intestines. Synonyms: TASP0390325, TASP 0390325, TASP-0390325. Grades: >98%. CAS No. 104121-92-8. Molecular formula: C30H50O5. Mole weight: 490.72.
Eldecalcitol
Eldecalcitol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R,3R,Z)-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol. CAS No. 104121-92-8. Molecular formula: C30H50O5. Mole weight: 490.72. Catalog: APB104121928.
Eldecalcitol
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3. CAS No. 104121-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-A0020.
Eldecalcitol Intermediate A
Eldecalcitol Intermediate A is an intermediate of eldecalcitol, a vitamin D3 analogue for the treatment of osteoporosis. Eldecalcitol is more active in bone resorption inhibition in comparison with alfacalcidol. Synonyms: 3-[(1R,2R,4Z,6R)-2,6-bis[[tert-butyl(dimethyl)silyl]oxy]-4-(2-diphenylphosphorylethylidene)-3-methylidenecyclohexyl]oxypropoxy-tert-butyl-dimethylsilane. CAS No. 200636-54-0. Molecular formula: C42H71O5PSi3. Mole weight: 771.254.
Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-936557; MDX-1100. CAS No. 946414-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99190.
Eldelumab
Eldelumab is a humanized anti-CXCL10 (IP-10) monoclonal antibody that binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab has been use for the treatment of ulcerative colitis. Synonyms: BMS-936557; MDX-1100. CAS No. 946414-98-8.
Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart's electrical cycle) in patients with long QT-3 (LQT3) syndrome. Phase III clinical trilas for the treatment of Long QT syndrome, Phase II/III clinical trilas for the treatment of Hypertrophic cardiomyopathy and Phase II clinical trilas for the treatment of Ventricular arrhythmias are on-going. Uses: Long qt syndrome;hypertrophic cardiomyopathy;ventricular arrhythmias. Synonyms: GS-6615; GS 6615; GS6615; Eleclazine. 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]- 3,4-dihydro-1,4-benzoxazepin-5(2H)-one. Grades: 98%. CAS No. 1443211-72-0. Molecular formula: C21H16F3N3O3. Mole weight: 415.37.