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Eicosane-[d42]. Synonyms: Deuterated eicosane; Eicosane-d42. Grade: 98% by CP; 98% atom D. CAS No. 62369-67-9. Molecular formula: C20D42. Mole weight: 324.81.
Eicosanedioic acid
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis. Uses: Scientific research. Group: Natural products. CAS No. 2424-92-2. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W034595.
Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences.
Worldwide
Eicosapentaenoic Acid
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA; Timnodonic acid. CAS No. 10417-94-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0660.
Eicosapentaenoic Acid
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grade: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46.
Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d 5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: EPA-d5; Timnodonic acid-d5. CAS No. 1197205-73-4. Pack Sizes: 1 mg (1.63 mM * 2 mL in Ethanol). Product ID: HY-B0660S.
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0747.
Eicosapentaenoic Acid Ethyl Ester
Eicosapentaenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: EPA 90E; Incromega E 7010. Grades: Highly Purified. CAS No. 73310-10-8. Pack Sizes: 100mg. Molecular Formula: C22H34O2, Molecular Weight: 330.5. US Biological Life Sciences.
Worldwide
Eicosapentaenoic Acid Impurity10
Eicosapentaenoic Acid Impurity10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123940-93-2. Molecular formula: C22H36O2. Mole weight: 332.53. Catalog: APB123940932.
Eicosapentaenoic Acid Impurity5
Eicosapentaenoic Acid Impurity5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 140670-40-2. Molecular formula: C25H38O4. Mole weight: 402.58. Catalog: APB140670402.
Eicosapentaenoic Acid Impurity6
Eicosapentaenoic Acid Impurity6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124538-05-2. Molecular formula: C47H68O5. Mole weight: 713.06. Catalog: APB124538052.
Eicosapentaenoic acid methyl ester
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis) [1]. Uses: Scientific research. Group: Natural products. CAS No. 2734-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011311.
Eicosapentaenoyl ethanolamide
5 mg/mL in absolute ethanol, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Eicosatetraynoic acid
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase ( ID 50 =8 μM and 4 μM, respectively) [1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM [2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro [3]. Eicosatetraynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETYA. CAS No. 1191-85-1. Pack Sizes: 1 mg. Product ID: HY-124108.
Eicosatetraynoic acid
ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; 1191-85-1; Eicosatetraynoic acid; icosa-5,8,11,14-tetraynoic acid; eicosatetranoic acid; Ro 3-1428; Octadehydroarachidonic acid; 5FEJ8J06DR; MLS000069514; MFCD00036967; SMR000058640; MLS-0002886.0001; Ro 31428; ITY; Opera_ID_402; Spectrum5_001952; UNII-5FEJ8J06DR; cid_1780; CBiol_001864; SCHEMBL68751; BSPBio_001449; KBioGR_000169; KBioSS_000169; BML2-F04; CHE. Grade: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.40.
Eicosyltriethyl Ammonium bromide
Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences.
Worldwide
EIDD-1931
EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033.
EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grade: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22.
EIDD-2749
4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2. Synonyms: 4'-fluorouridine; 1613589-24-4; 4'-C-Fluoro-uridine; 1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 1613591-91-5; SCHEMBL6839661; RDCYLPRXPILMRP-JVZYCSMKSA-N; AMY30709; EX-A6732; DA-70078; MS-23688; 4'-fluorouridine (4'-FlU, EIDD-2749)?; 1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: 98%. CAS No. 1613589-24-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
EIDD-2749
EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4'-FlU; 4'-Fluorouridine. CAS No. 1613589-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146246.
EIDD-2801
EIDD-2801, derived from N4-hydroxycytidine, is an oral bioavailable broad-spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester; Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-; EIDD 1931-isopropyl ester; Lagevrio; MK-4482; β-D-N4 hydroxycytidine-5'-isopropyl ester. Grade: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31.
A cell-permeable N,N'-diarylurea that acts as an inhibitor of the formation of the ternary complex of eukaryotic translation initiation factor 2 (eIF2), GTP and the initiator methionine tRNA (Met-tRNAi), a key regulatory step of translation initiation. It directly activates heme-regulated inhibitor kinase (HRI), which then phosphorylates eIF2a in cells at 10uM and in cell-free extracts dose-dependently, and thereby prevents respective ternary complex formation without elevating oxidative stress. The sensitivities of various cancer cell lines to the anti-proliferative effects of this compound are shown to correlate with the expression of HRI. Furthermore, this compound displays tumor growth inhibition in a mice xenograft model of MCF-7 human breast cancer cells at 175mg/kg, in vivo.CAS No:1257423-87-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1257423-87-2. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?OS, Molecular Weight: 339.2. US Biological Life Sciences.
A negative control for eIF2-GTP-tRNAiMet ternary complex Inhibitor, BTdCPU. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
eIF-2? Inhibitor II, Sal003 - CAS 301359-91-1
The eIF-2? Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
EIF2S1, His tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
eIF4A3-IN-1
eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. It binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. Synonyms: eIF4A3-IN-1; 2095486-67-0; CHEMBL4073833; BDBM50265561; AKOS040733081; MS-30511; HY-101513; CS-0021616; 3-[4-[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)piperazine-1-carbonyl]-5-methylpyrazol-1-yl]benzonitrile. Grade: 99%. CAS No. 2095486-67-0. Molecular formula: C29H23BrClN5O2. Mole weight: 588.88.
eIF4A3-IN-1
eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 ?M; Kd: 0.043 ?M) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095486-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101513.
eIF4A3-IN-2
eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM. Synonyms: eIF4A3 inhibitor, 2. Grade: 99%. CAS No. 2095677-20-4. Molecular formula: C25H19Br2ClN4O2. Mole weight: 602.71.
eIF4A3-IN-2
eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095677-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101785.
eIF4A3-IN-4
eIF4A3-IN-4 is an inhibitor of eukaryotic initiation factor 4A (eIF4A) with an IC50 of 8.6 μM. Synonyms: eIF4A3-IN-4; CS-0256185. Molecular formula: C24H20N2O5. Mole weight: 416.43.
eIF4A3-IN-5
eIF4A3-IN-5, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Synonyms: 6H-Cyclopenta[4,5]furo[3,2-c]pyridine-7-carboxylic acid, 5a-(4-cyanophenyl)-5a,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-, (5aR,6S,7R,8R,8aS)-. CAS No. 2100145-31-9. Molecular formula: C26H22N2O7. Mole weight: 474.46.
eIF4A3-IN-6
eIF4A3-IN-6, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Synonyms: Benzonitrile, 4-[(5aR,6S,7S,8R,8aS)-7-(aminomethyl)-6,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-5aH-cyclopenta[4,5]furo[3,2-c]pyridin-5a-yl]-. CAS No. 2100133-77-3. Molecular formula: C26H25N3O5. Mole weight: 459.49.
eIF4A3-IN-7
eIF4A3-IN-7 is an effective inhibitor of eIF4A3, which has the potential to study cancer and other dysproliferative diseases. (extracted from patent WO2019161345A1, Compound 8). Synonyms: 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-3a-(4-hydroxyphenyl)-6,8-dimethoxy-3-phenyl-, (1R,2R,3S,3aR,8bS)-. CAS No. 2374759-82-5. Molecular formula: C26H25NO7. Mole weight: 463.48.
eIF4E Active human
N-terminal GST-tag, recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9
The eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, also referenced under CAS 315706-13-9, controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
eIF4E-IN-1
eIF4E-IN-1, a potent eIF4E inhibitor, inhibits immunosuppression components such as the immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immunosuppression in certain diseases, such as cancer and infectious diseases. (Extracted from patent WO2021003194A1, compound Y). Synonyms: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-(4-methyl-1-piperazinyl)-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-31-2. Molecular formula: C33H28ClF3N6O4S. Mole weight: 697.13.
eIF4E-IN-2
eIF4E-IN-2, a potent inhibitor of eukaryotic initiation factor 4e (eIF4e), has the potential to study eIF4e-dependent diseases, including cancer. (Extracted from patent WO2021003157A1, compound 1188). Synonyms: 7-(5-chloro-2-(3-(5-cyano-6-((1-(3,3-difluorocyclobutyl)piperidin-4-yl)(methyl)amino)-2-methyl-4-oxopyrido[3,4-d]pyrimidin-3(4H)-yl)prop-1-yn-1-yl)phenyl)-N-(methylsulfonyl)thieno[3,2-b]pyridine-3-carboxamide. CAS No. 2575840-38-7. Molecular formula: C37H33ClF2N8O4S2. Mole weight: 791.29.
eIF4E-IN-2
eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e). eIF4E-IN-2 has the potential for researching eIF4e dependent diseases, including the research of cancer (extracted from patent WO2021003157A1, compound 1188)[1]. eIF4E-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2575840-38-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145262.
eIF4E-IN-3
eIF4E-IN-3, a potent inhibitor of eukaryotic initiation factor 4e (eIF4e), has the potential to study eIF4e-dependent diseases, including cancer. (Extracted from patent WO2021003157A1, compound 485). Synonyms: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-[(4-methyl-1-piperazinyl)methyl]-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-29-8. Molecular formula: C34H30ClF3N6O4S. Mole weight: 711.15.
EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis [1]. Uses: Scientific research. Group: Peptides. CAS No. 239075-62-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3533.
EIPA
EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840.
EIPA
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grade: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76.
EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 1154-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
EIPA hydrochloride
EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A.
EIPA hydrochloride
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22.
EIT hydrobromide
EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08.
EIT hydrobromide
EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ekatetrone
It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31.
EL-102
EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grade: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47.
ELA-11 (human)
ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grade: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57.
ELA-11 (human) acetate
ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) acetate inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Molecular formula: C60H94N16O15S2. Mole weight: 1343.61.
ELA-14 (human)
ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03.
ELA-14 (human) acetate
ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grade: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09.
ELA-14 negative control
Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93.
ELA-21 (human)
ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grade: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12.
ELA-32 (human)
ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grade: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8.