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It is originally isolated from Farrowia sp. E-1941. EI-1941-1 inhibited recombinant human ICE with an IC50 of 0.086 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 2,3-Dihydroxy-5-propyl-1a,5,6,7a-tetrahydro-2H-oxireno[g]isochromen-7(3H)-one. CAS No. 189828-31-7. Molecular formula: C12H16O5. Mole weight: 240.25.
EI-1941-2
It is originally isolated from Farrowia sp. E-1941. EI-1941-2 inhibited recombinant human ICE with an IC50 of 0.006 μmol/L. It also inhibits elastase and cathepsin. CAS No. 189828-32-8. Molecular formula: C12H14O5. Mole weight: 238.24.
EI-2128-1
EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus. Synonyms: (2E)-N-[(1R,3S,4'S,5R,5'R,7S)-5'-Hydroxy-6-oxodihydro-3'H-spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'-furan]-4'-yl]-4,6-dimethyl-2-dodecenamide. Molecular formula: C23H35NO6. Mole weight: 421.53.
EI-2346
EI-2346 is originally isolated from Streptomyces sp. E-2346. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 3.9 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 3,10-Dihydroxy-8-[5-hydroxy-4-(hydroxymethyl)-1,3-dioxan-2-yl]-3-methyl-1-propyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione. Molecular formula: C22H26O9. Mole weight: 434.44.
Eicosadienoic acid(5Z,14Z)
Heterocyclic Organic Compound. Alternative Names: Eicosadienoic Acid (5Z,14Z), CTK8E7697, 122055-58-7. CAS No. 122055-58-7. Molecular formula: C20H36O2. Mole weight: 308.5. Appearance: A solution in ethanol. Purity: 0.96. IUPACName: icosa-5,14-dienoic acid. Canonical SMILES: CCCCCC=CCCCCCCCC=CCCCC(=O)O. Catalog: ACM122055587.
Eicosafluorononane
Eicosafluorononane. Group: Biochemicals. Alternative Names: Perfluorononane. Grades: Highly Purified. CAS No. 375-96-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis. Uses: Scientific research. Group: Natural products. CAS No. 2424-92-2. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W034595.
Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences.
Worldwide
Eicosapentaenoic Acid
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grades: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46.
Eicosapentaenoic Acid
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA; Timnodonic acid. CAS No. 10417-94-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0660.
Fatty Acids and Fatty Acid Esters2H Labeled Compounds. Alternative Names: Icosapent-d5; Icosapentaenoic acid-d5. CAS No. 1197205-73-4. Molecular formula: C20H25D5O2. Mole weight: 307.48. IUPACName: (5Z,8Z,11Z,14Z,17Z)-19,19,20,20,20-pentadeuterioicosa-5,8,11,14,17-pentaenoic acid. Density: 0.958 g/mL at 25 °C. Catalog: ACM1197205734.
Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d 5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: EPA-d5; Timnodonic acid-d5. CAS No. 1197205-73-4. Pack Sizes: 1 mg (1.63 mM * 2 mL in Ethanol). Product ID: HY-B0660S.
Eicosapentaenoic acid ethyl ester
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0747.
Eicosapentaenoic Acid Ethyl Ester
Eicosapentaenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: EPA 90E; Incromega E 7010. Grades: Highly Purified. CAS No. 73310-10-8. Pack Sizes: 100mg. Molecular Formula: C22H34O2, Molecular Weight: 330.5. US Biological Life Sciences.
Worldwide
Eicosapentaenoic Acid Impurity1
Eicosapentaenoic Acid Impurity1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-49-8. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827498.
Eicosapentaenoic Acid Impurity10
Eicosapentaenoic Acid Impurity10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123940-93-2. Molecular Formula: C22H36O2. Mole Weight: 332.53. Catalog: APB123940932.
Eicosapentaenoic Acid Impurity11
Eicosapentaenoic Acid Impurity11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2580285-53-4. Molecular Formula: C20H32O2. Mole Weight: 304.47. Catalog: APB2580285534.
Eicosapentaenoic Acid Impurity12
Eicosapentaenoic Acid Impurity12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H42O2. Mole Weight: 338.58. Catalog: APB12251.
Eicosapentaenoic Acid Impurity13
Eicosapentaenoic Acid Impurity13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB12253.
Eicosapentaenoic Acid Impurity14
Eicosapentaenoic Acid Impurity14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB12254.
Eicosapentaenoic Acid Impurity15
Eicosapentaenoic Acid Impurity15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C88H136O8. Mole Weight: 331.51. Catalog: APB12252.
Eicosapentaenoic Acid Impurity16
Eicosapentaenoic Acid Impurity16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2447131-67-9. Molecular Formula: C22H32O2. Mole Weight: 328.5. Catalog: APB2447131679.
Eicosapentaenoic Acid Impurity2
Eicosapentaenoic Acid Impurity2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-50-1. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827501.
Eicosapentaenoic Acid Impurity3
Eicosapentaenoic Acid Impurity3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 173936-49-7. Molecular Formula: C20H30O2. Mole Weight: 302.46. Catalog: APB173936497.
Eicosapentaenoic Acid Impurity4
Eicosapentaenoic Acid Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-48-7. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827487.
Eicosapentaenoic Acid Impurity5
Eicosapentaenoic Acid Impurity5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 140670-40-2. Molecular Formula: C25H38O4. Mole Weight: 402.58. Catalog: APB140670402.
Eicosapentaenoic Acid Impurity6
Eicosapentaenoic Acid Impurity6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124538-05-2. Molecular Formula: C47H68O5. Mole Weight: 713.06. Catalog: APB124538052.
Eicosapentaenoic Acid Impurity7
Eicosapentaenoic Acid Impurity7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2692622-82-3. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB2692622823.
Eicosapentaenoic Acid Impurity8
Eicosapentaenoic Acid Impurity8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB12250.
Eicosapentaenoic Acid Impurity9
Eicosapentaenoic Acid Impurity9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB12249.
Eicosapentaenoic acid methyl ester
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis) [1]. Uses: Scientific research. Group: Natural products. CAS No. 2734-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011311.
Eicosatetraynoic acid
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase ( ID 50 =8 μM and 4 μM, respectively) [1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM [2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro [3]. Eicosatetraynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETYA. CAS No. 1191-85-1. Pack Sizes: 1 mg. Product ID: HY-124108.
Eicosatetraynoic Acid
ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; Octadehydroarachidonic acid. Grades: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.4.
Eicosyltriethyl Ammonium bromide
Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences.
Worldwide
EIDD-1931
EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033.
EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22.
EIDD-2801
EIDD-2801 derived from a N(4)-hydroxycytidine, is an orally bioavailable broad spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester. Grades: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31.
A cell-permeable N,N'-diarylurea that acts as an inhibitor of the formation of the ternary complex of eukaryotic translation initiation factor 2 (eIF2), GTP and the initiator methionine tRNA (Met-tRNAi), a key regulatory step of translation initiation. It directly activates heme-regulated inhibitor kinase (HRI), which then phosphorylates eIF2a in cells at 10uM and in cell-free extracts dose-dependently, and thereby prevents respective ternary complex formation without elevating oxidative stress. The sensitivities of various cancer cell lines to the anti-proliferative effects of this compound are shown to correlate with the expression of HRI. Furthermore, this compound displays tumor growth inhibition in a mice xenograft model of MCF-7 human breast cancer cells at 175mg/kg, in vivo.CAS No:1257423-87-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1257423-87-2. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?OS, Molecular Weight: 339.2. US Biological Life Sciences.
A negative control for eIF2-GTP-tRNAiMet ternary complex Inhibitor, BTdCPU. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
EILEVPST
EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis [1]. Uses: Scientific research. Group: Peptides. CAS No. 239075-62-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3533.
EIPA
EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840.
EIPA
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76.
EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 1154-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
EIPA hydrochloride
EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A.
EIPA hydrochloride
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22.
Eisen(II)-gluconat
Heterocyclic Organic Compound. CAS No. 12389-15-10. Catalog: ACM123891510.
E-isomer Cefmenoxime impurity
E-isomer Cefmenoxime impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Molecular Formula: C16H17N9O5S3. Mole Weight: 511.56. Catalog: APB04428.
EIT hydrobromide
EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08.
EIT hydrobromide
EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ekatetrone
It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31.
EL-102
EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grades: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47.
ELA
ELA is a ELABELA mutant peptide and also a negative control for ELA-32. Elabela is one of two endogenous ligands for the G-protein-coupled APLNR receptor. Molecular formula: C162H271N57O39S4. Mole weight: 3769.55.
ELA-11 (human)
ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grades: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57.
ELA-14 (human)
ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03.
ELA-14 (human) acetate
ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09.
ELA-14 negative control
Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93.
ELA-21 (human)
ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grades: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12.
ELA-32 (human)
ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grades: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8.
Elacestrant
Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Synonyms: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Molecular formula: C30H38N2O2. Mole weight: 458.65.
Elacestrant
Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19822.
Elacestrant dihydrochloride
Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A.