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Product
Eicosapentaenoic Acid Impurity13 Eicosapentaenoic Acid Impurity13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB12253. Alfa Chemistry Analytical Products 4
Eicosapentaenoic Acid Impurity14 Eicosapentaenoic Acid Impurity14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB12254. Alfa Chemistry Analytical Products 4
Eicosapentaenoic Acid Impurity15 Eicosapentaenoic Acid Impurity15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C88H136O8. Mole Weight: 331.51. Catalog: APB12252. Alfa Chemistry Analytical Products 4
Eicosapentaenoic Acid Impurity16 Eicosapentaenoic Acid Impurity16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2447131-67-9. Molecular Formula: C22H32O2. Mole Weight: 328.5. Catalog: APB2447131679. Alfa Chemistry Analytical Products 2
Eicosapentaenoic Acid Impurity2 Eicosapentaenoic Acid Impurity2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-50-1. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827501. Alfa Chemistry Analytical Products
Eicosapentaenoic Acid Impurity3 Eicosapentaenoic Acid Impurity3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 173936-49-7. Molecular Formula: C20H30O2. Mole Weight: 302.46. Catalog: APB173936497. Alfa Chemistry Analytical Products
Eicosapentaenoic Acid Impurity4 Eicosapentaenoic Acid Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125827-48-7. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB125827487. Alfa Chemistry Analytical Products
Eicosapentaenoic Acid Impurity5 Eicosapentaenoic Acid Impurity5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 140670-40-2. Molecular Formula: C25H38O4. Mole Weight: 402.58. Catalog: APB140670402. Alfa Chemistry Analytical Products
Eicosapentaenoic Acid Impurity6 Eicosapentaenoic Acid Impurity6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124538-05-2. Molecular Formula: C47H68O5. Mole Weight: 713.06. Catalog: APB124538052. Alfa Chemistry Analytical Products
Eicosapentaenoic Acid Impurity7 Eicosapentaenoic Acid Impurity7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2692622-82-3. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB2692622823. Alfa Chemistry Analytical Products 2
Eicosapentaenoic Acid Impurity8 Eicosapentaenoic Acid Impurity8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H32O2. Mole Weight: 316.49. Catalog: APB12250. Alfa Chemistry Analytical Products 4
Eicosapentaenoic Acid Impurity9 Eicosapentaenoic Acid Impurity9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H34O2. Mole Weight: 330.51. Catalog: APB12249. Alfa Chemistry Analytical Products 4
Eicosapentaenoic acid methyl ester Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis) [1]. Uses: Scientific research. Group: Natural products. CAS No. 2734-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011311. MedChemExpress MCE
Eicosatetraynoic acid Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase ( ID 50 =8 μM and 4 μM, respectively) [1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM [2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro [3]. Eicosatetraynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETYA. CAS No. 1191-85-1. Pack Sizes: 1 mg. Product ID: HY-124108. MedChemExpress MCE
Eicosatetraynoic Acid ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; Octadehydroarachidonic acid. Grades: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.4. BOC Sciences 10
Eicosyltriethyl Ammonium bromide Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences. USBiological 7
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EIDD-1931 EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033. MedChemExpress MCE
EIDD-1931 EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. BOC Sciences 9
EIDD-1931 EIDD-1931 Inhibitor. Uses: Scientific use. Product Category: T8498. CAS No. 3258-2-4. TARGETMOL CHEMICALS
EIDD-2801 EIDD-2801 derived from a N(4)-hydroxycytidine, is an orally bioavailable broad spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester. Grades: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31. BOC Sciences 9
eIF2-GTP-tRNAiMet Ternary Complex Inhibitor, BTdCPU (N,N'-diarylurea;translation Initiation Tenrary Complex Inhibitor, 1-(benzo[d][1, 2, 3]thiadiazol-6-yl)-3-(3, 4-dichlorophenyl)urea, BTdCPU, Heme-regulated Inhibitor Kinase Activator, BTdCPU) A cell-permeable N,N'-diarylurea that acts as an inhibitor of the formation of the ternary complex of eukaryotic translation initiation factor 2 (eIF2), GTP and the initiator methionine tRNA (Met-tRNAi), a key regulatory step of translation initiation. It directly activates heme-regulated inhibitor kinase (HRI), which then phosphorylates eIF2a in cells at 10uM and in cell-free extracts dose-dependently, and thereby prevents respective ternary complex formation without elevating oxidative stress. The sensitivities of various cancer cell lines to the anti-proliferative effects of this compound are shown to correlate with the expression of HRI. Furthermore, this compound displays tumor growth inhibition in a mice xenograft model of MCF-7 human breast cancer cells at 175mg/kg, in vivo.CAS No:1257423-87-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1257423-87-2. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?OS, Molecular Weight: 339.2. US Biological Life Sciences. USBiological 4
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eIF2-GTP-tRNAiMet Ternary Complex Inhibitor Negative Control, NCPdCPU (1-(2-chloro-5-nitrophenyl)-3-(3,4-dichlorophenyl)urea) A negative control for eIF2-GTP-tRNAiMet ternary complex Inhibitor, BTdCPU. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
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EILEVPST EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis [1]. Uses: Scientific research. Group: Peptides. CAS No. 239075-62-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3533. MedChemExpress MCE
EIPA EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. BOC Sciences 8
EIPA EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840. MedChemExpress MCE
EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide) EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 1154-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 4
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EIPA hydrochloride EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A. MedChemExpress MCE
EIPA hydrochloride EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. BOC Sciences 8
E-isomer Cefmenoxime impurity E-isomer Cefmenoxime impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Molecular Formula: C16H17N9O5S3. Mole Weight: 511.56. Catalog: APB04428. Alfa Chemistry Analytical Products 4
EIT hydrobromide EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08. BOC Sciences 10
EIT hydrobromide EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ekatetrone It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. BOC Sciences 5
EL-102 EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grades: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47. BOC Sciences 9
ELA ELA is a ELABELA mutant peptide and also a negative control for ELA-32. Elabela is one of two endogenous ligands for the G-protein-coupled APLNR receptor. Molecular formula: C162H271N57O39S4. Mole weight: 3769.55. BOC Sciences 11
ELA-11 (human) ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grades: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57. BOC Sciences 10
ELA-14 (human) ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. BOC Sciences 3
ELA-14 (human) acetate ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. BOC Sciences 6
ELA-14 negative control Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93. BOC Sciences 11
ELA-21 (human) ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grades: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12. BOC Sciences 10
ELA-32 (human) ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grades: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8. BOC Sciences 11
Elacestrant Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19822. MedChemExpress MCE
Elacestrant Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Synonyms: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Molecular formula: C30H38N2O2. Mole weight: 458.65. BOC Sciences 10
Elacestrant dihydrochloride Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A. MedChemExpress MCE
Elacestrant HCl Elacestrant , also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAD1901; RAD-1901; RAD 1901; RAD1901 HCl salt; Elacestrant dihydrochloride; Elacestrant HCl. Product Category: Others. Appearance: Solid powder. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. Purity: >98%. IUPACName: (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride. Canonical SMILES: OC1=CC=C2C[C@H](C3=CC=C(OC)C=C3N(CC4=CC=C(CCNCC)C=C4)CC)CCC2=C1.[H]Cl.[H]Cl. Product ID: ACM1349723938. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Elacestrant S enantiomer Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63. BOC Sciences 10
Elacestrant S enantiomer dihydrochloride Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. BOC Sciences 10
Elacridar Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654. BOC Sciences 8
Elacridar Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences. USBiological 7
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Elacridar Elacridar. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. Appearance: Solid. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.6. Purity: 0.98. Product ID: ACM143664113. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Elacridar-d4 (Major) A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport. Group: Biochemicals. Alternative Names: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl-d4]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918-d4; GG 918-d4; GW 0918-d4. Grades: Highly Purified. CAS No. 1189481-51-3. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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Elacridar hydrochloride Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Synonyms: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10. BOC Sciences 8
Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-­2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-m­ethoxy-9-oxo-4-acridinecarboxamide hydrochloride) P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
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Elacytarabine Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 4055. CAS No. 188181-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14941. MedChemExpress MCE
Elacytarabine Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Synonyms: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67. BOC Sciences 11
Elafibranor Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Synonyms: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E) -1-[4- (Methylthio) phenyl]-3-[3, 5-dimethyl-4-[ (carboxydimethylmethyl) oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49. BOC Sciences 8
Elafibranor Elafibranor (GFT505) is a PPARα/δ agonist with EC 50 s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16737. MedChemExpress MCE
Elagolix Elagolix. Uses: For analytical and research use. Group: Impurity standards. CAS No. 834153-87-6. Molecular Formula: C32H30F5N3O5. Mole Weight: 631.6. Catalog: APB834153876. Alfa Chemistry Analytical Products 3
Elagolix Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Synonyms: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6. BOC Sciences 11
Elagolix Impurity 1 Elagolix Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4-((2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C25H24F4N3NaO4. Mole Weight: 529.46. Catalog: APB05845. Alfa Chemistry Analytical Products 4
Elagolix Impurity 10 Elagolix Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-fluoro-3-methoxyphenyl)-6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C20H16F4N2O3. Mole Weight: 408.35. Catalog: APB05841. Alfa Chemistry Analytical Products 4
Elagolix Impurity 11 Elagolix Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C20H16F4N2O3. Mole Weight: 408.35. Catalog: APB05839. Alfa Chemistry Analytical Products 4
Elagolix Impurity 12 Elagolix Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)-2-hydroxybenzamide. Molecular Formula: C35H28F5N3O5. Mole Weight: 665.61. Catalog: APB05840. Alfa Chemistry Analytical Products 4
Elagolix Impurity 13 Elagolix Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl. CAS No. 2316733-82-9. Molecular Formula: C14H12F2O2. Mole Weight: 250.24. Catalog: APB2316733829. Alfa Chemistry Analytical Products 2
Elagolix Impurity 14 Elagolix Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05838. Alfa Chemistry Analytical Products 4
Elagolix Impurity 15 Elagolix Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H11F3N2O2. Mole Weight: 284.23. Catalog: APB05837. Alfa Chemistry Analytical Products 4
Elagolix Impurity 16 Elagolix Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-4-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05836. Alfa Chemistry Analytical Products 4
Elagolix Impurity 17 Elagolix Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-fluoro-2-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05835. Alfa Chemistry Analytical Products 4
Elagolix Impurity 19 Elagolix Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 2354391-45-8. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB2354391458. Alfa Chemistry Analytical Products 2
Elagolix Impurity 19Q Elagolix Impurity 19Q. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-60-9. Molecular Formula: C36H36F5N3O7. Mole Weight: 717.69. Catalog: APB2409132609. Alfa Chemistry Analytical Products 2
Elagolix Impurity 2 Elagolix Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-64-3. Molecular Formula: C38H40F5N3O6. Mole Weight: 729.75. Catalog: APB2409132643. Alfa Chemistry Analytical Products 2

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