A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Emixustat is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429. CAS No. 1141777-14-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720.
Emixustat
Emixustat, a novel visual cycle modulator, is a nonretinoid compound that directly inhibits RPE65, but does not bind to RAR/ RXR retinoid receptors or antagonize retinoid binding proteins. Synonyms: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol; ACU-4429; emixustat. CAS No. 1141777-14-1. Molecular formula: C16H25NO2. Mole weight: 263.38.
Emixustat hydrochloride
Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429 hydrochloride. CAS No. 1141934-97-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720A.
Emixustat hydrochloride
The hydrochloride salt form of Emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Uses: The hydrochloride salt form of emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Synonyms: Emixustat (hydrochloride); UNII-AP4OF2M98B; AP4OF2M98B; EMIXUSTAT HYDROCHLORIDE; 1141934-97-5; Emixustat hydrochloride (USAN). Grades: 98%. CAS No. 1141934-97-5. Molecular formula: C16H26ClNO2. Mole weight: 299.84.
EML-425
EML-425, a diazinane derivative, has been found to be a CBP/p300 inhibitor that could probably be significant in studies of human leukemia cells. IC50: 1.1 and 2.9 μM, respectively. Synonyms: EML 425; EML-425; EML425; MolPort-042-624-542; BDBM50081125; AKOS027470241; 1,3-dibenzyl-5-[(4-hydroxy-2,6-dimethylphenyl)methylidene]-1,3-diazinane-2,4,6-trione. Grades: 98%. CAS No. 1675821-32-5. Molecular formula: C27H24N2O4. Mole weight: 440.49.
Emlenoflast
MCC7840 is a sulfonylurea non-steroidal anti-inflammatory drug and a potent selective inhibitor of NLRP3 inflammasome with IC50 <100 nM. Synonyms: N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-1-(propan-2-yl)-1H-pyrazole-3-sulfonamide; Inzomelid; 1H-Pyrazole-3-sulfonamide, N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-1-(1-methylethyl)-; N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide; MCC7840. CAS No. 1995067-59-8. Molecular formula: C19H24N4O3S. Mole weight: 388.48.
Emodepside
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay 44-4400. CAS No. 155030-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101476.
Emodin
100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics, Stains & Indicators. Formula: C15H10O5. CAS No. 518-82-1. Prepack ID 12987447-100mg. Molecular Weight 270.24. See USA prepack pricing.
Emodin
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,8-trihydroxy-6-methylanthraqunone. Product Category: Inhibitors. Appearance: Powder. CAS No. 518-82-1. Molecular formula: C15H10O5. Mole weight: 270.24. Purity: 0.98. IUPACName: 1,3,8-Trihydroxy-6-methylanthracene-9,10-dione. Canonical SMILES: CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O. Density: 1.33 g/ml. Product ID: ACM518821-1. Alfa Chemistry ISO 9001:2015 Certified.
Emodin
Emodin (Frangula emodin), an anthraquinone derivative, is an anti- SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction [1]. Emodin inhibits casein kinase-2 ( CK2 ). Anti-inflammatory and anticancer effects [2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC 50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Frangula emodin. CAS No. 518-82-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-14393.
Emodin-1-Beta-D-Glucoside
Emodin-1-Beta-D-Glucoside is an antioxidant and anti-inflammatory compound used for studying cancer, inflammation and microbial infections. Synonyms: Emodin 1-O-beta-D-glucoside; Emodin-1-O-glucoside; Emodin-1-O-|A-D-glucopyranoside; Emodin-1-Beta-D-Glucoside; 513F53H6BU; Emodin-1-O-beta-D-glucopyranoside; UNII-513F53H6BU; 1,3-dihydroxy-6-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione; EMODIN 1-GLUCOSIDE; 9,10-Anthracenedione, 1-(beta-D-glucopyranosyloxy)-6,8-dihydroxy-3-methyl-; modin 1-glucoside; EMODIN-1-GLUCOSIDE; Emodin 1-Beta-D-Glucoside; Emodin-1-O-beta-D-glucoside; CHEMBL457945; Emodin-1-O-b-D-glucopyranoside; DTXSID201020031; Emodin-1-O-??-D-glucopyranoside; EMODIN 1-.BETA.-GLUCOSIDE; HY-N2394; AKOS030573570; EMODIN 1-O-.BETA.-D-GLUCOSIDE; AC-34144; MS-27708; 1-O-.BETA.-D-GLUCOPYRANOSYLEMODIN; EMODIN 1-.BETA.-D-GLUCOPYRANOSIDE; CS-0022596; EMODIN 1-O-.BETA.-D-GLUCOPYRANOSIDE; F17665; Q27260855; 9,10-ANTHRACENEDIONE, 1-(.BETA.-D-GLUCOPYRANOSYLOXY)-6,8-DIHYDROXY-3-METHYL-. Grades: > 95%. CAS No. 38840-23-2. Molecular formula: C21H20O10. Mole weight: 432.38.
Emodin 1-glucoside
Emodin 1-glucoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 38840-23-2. Pack Sizes: 5mg. US Biological Life Sciences.
Emodin-8-glucoside (Emodin-8-O- β-D-glucopyranoside). Group: Biochemicals. Grades: Plant Grade. CAS No. 23313-21-5. Pack Sizes: 10mg. Molecular Formula: C21H20O10, Molecular Weight: 432.38. US Biological Life Sciences.
Worldwide
Emodin anthrone
Emodin anthrone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: emodin anthrone;1,3,8-Trihydroxy-6-methyl-10H-anthracen-9-one;1,6,8-Trihydroxy-3-methyl-10-hydroanthracen-9-one;9(10H)-Anthracenone, 1,3,8-trihydroxy-6-methyl-;Aids002046;Aids-002046. Product Category: Heterocyclic Organic Compound. CAS No. 491-60-1. Molecular formula: C15H12O4. Mole weight: 256.25. Product ID: ACM491601. Alfa Chemistry ISO 9001:2015 Certified.
Emodin anthrone
Emodin anthrone is a natural product found in Rhamnus prinoides, Paeonia emodi, and Rumex acetosa with data available. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli. Synonyms: Emodinanthrone; emodin-9-anthrone; Emodinol; Protophyscihydrone; 2,4,5-trihydroxy-7-methylanthracen-10(9H)-one. Grades: 95%. CAS No. 491-60-1. Molecular formula: C15H12O4. Mole weight: 256.25.
Emodin - CAS 518-82-1
A cell-permeable, reversible, substrate competitive and potent p56lck tyrosine kinase inhibitor (IC?? = 18.5 μM). Group: Fluorescence/luminescence spectroscopy.
Emodin-d4
Labeled Emodin. Occurs mostly as the rhamnoside (see Frangulin) in rhubarb root. Cathartic. Group: Biochemicals. Alternative Names: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione-d4; 1,6,8-Trihydroxy-3-methylanthraquinone-d4; 4,5,7-Trihydroxy-2-methyl-anthraquinone-d4; Archin-d4; Emodin-d4; Emodol-d4; Frangula Emodin-d4; Frangulic Acid-d4; NSC 622947-d4; Rheum Emodin-d4; Schuttgelb-d4. Grades: Highly Purified. CAS No. 132796-52-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Emodin-d4
Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Emodin-d4;1,3,8-Trihydroxy-6-Methyl-9,10-anthracenedione-d4;1,6,8-Trihydroxy-3-Methylanthraquinone-d4;4,5,7-Trihydroxy-2-Methyl- anthraquinone-d4;Archin-d4;EModol-d4;Frangula EModin-d4;Frangulic Acid-d4. Product Category: Inhibitors. Appearance: Brownish Solid. CAS No. 132796-52-2. Molecular formula: C15H10O5. Mole weight: 270.2369. Purity: 0.96. IUPACName: 1,3,6,8-tetradeuterio-2,4,5-trihydroxy-7-methylanthracene-9,10-dione. Canonical SMILES: O=C1C2=C(O)C([2H])=C(C)C([2H])=C2C(C3=C([2H])C(O)=C([2H])C(O)=C31)=O. Product ID: ACM132796522. Alfa Chemistry ISO 9001:2015 Certified.
Emodine
Emodine - Product ID: NST-10-73. Category: Anthraquinones. Alternative Names: 4,5,7-Trihydroxy-2-methylanthraquinone. Purity: 98%. Test method: HPLC. CAS No. 518-82-1. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Orange Powder. Molecular formula: C15H10O5. Mole weight: 270.24. Storage: +2 +8 °C.
emodin O-methyltransferase
The enzyme is involved in biosynthesis of the seco-anthraquinone (+)-geodin. Group: Enzymes. Synonyms: EOMT. Enzyme Commission Number: EC 2.1.1.283. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1890; emodin O-methyltransferase; EC 2.1.1.283; EOMT. Cat No: EXWM-1890.
Emodin, p56lck Tyrosine Kinase Inhibitor
Occurs mostly as the rhamnoside (see Frangulin) in rhubarb root. Cathartic. Cell-permeable. A naturally occurring anthraquinone that displays a range of biological activities including anti- inflammatory, anti-tumor and neuroprotective effects. Acts as a potent p56lck tyrosine kinase inhibitor (IC50 = 18.5uM). Group: Biochemicals. Alternative Names: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Emodin; Emodol; Frangula Emodin; Frangulic Acid; NSC 408120; NSC 622947; Rheum Emodin; Schuttgelb. Grades: Highly Purified. CAS No. 518-82-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??O?, Molecular Weight: 270.24. US Biological Life Sciences.
Worldwide
Emopamil
Emopamil is a calcium channel blocker that can be used to prevent renal injury after warm & cold ischemia. Uses: Calcium channel blockers. Synonyms: Emopamil; 78370-13-5; Emopamil [INN]; Emopamilum [Latin]; Emopamilo [Spanish]. Grades: 95%. CAS No. 78370-13-5. Molecular formula: C23H30N2. Mole weight: 334.504.
Emoxipine
Emoxipine. Group: Biochemicals. Alternative Names: 2-Ethyl-6-methyl-3-pyridinol; 2-Ethyl-3-hydroxy-6-methylpyridine; 2-Ethyl-6-methyl-3-hydroxypyridine. Grades: Highly Purified. CAS No. 2364-75-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H11NO. US Biological Life Sciences.
Worldwide
Emoxypine succinate
Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Ethyl-3-hydroxy-6-methylpyridine succinate. CAS No. 127464-43-1. Pack Sizes: 500 mg; 1 g. Product ID: HY-W002620A.
EMPA
EMPA. Group: Biochemicals. Alternative Names: N-Ethyl-2-[ (6-methoxy-3-pyridinyl) [ (2-methylphenyl) sulfonyl]amino]-N- (3-pyridinylmethyl) -acetamide. Grades: Highly Purified. CAS No. 680590-49-2. Pack Sizes: 10mg. Molecular Formula: C23H26N4O4S, Molecular Weight: 454.54. US Biological Life Sciences.
Worldwide
EMPA
EMPA is a high-affinity, reversible and selective orexin OX 2 receptor antagonist. [ 3 H]EMPA binds to human and rat OX 2 -HEK293 membranes with K D values of 1.1 and 1.4 nM respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 680590-49-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108682.
EMPA
EMPA is a potent and selective OX2 receptor antagonist (IC50 = 2.3 nM and 1900 nM for OX2 and OX1, respectively) with no activity at a panel of 80 receptors. EMPA blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 = 7.9 nM and 8.8 nM, respectively) and reverses orexin-B-induced hyperlocomotion in mice. Synonyms: N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide. Grades: ≥98% by HPLC. CAS No. 680590-49-2. Molecular formula: C23H26N4O4S. Mole weight: 454.54.
Empagliflozin
Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 ( SGLT-2 ) inhibitor with an IC 50 of 3.1 nM for human SGLT-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 10773. CAS No. 864070-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15409.
Empagliflozin
Potent, selective and competitive inhibitor of sodium-glucose cotransporter SGLT2, which is implicated in renal glucose reabsorption. The compound increases urinary glucose excretion, helps decrease hyperglyceamia and maintains glucose homeostasis in diabetic individuals. It has been associated with weight loss, lower blood pressure and decreased glycated haemoglobin. Animal studies suggest that empagliflozin preserves regeneration of β-cells in pancreatic Langerhans islets. Group: Biochemicals. Alternative Names: (1S) -1, 5-Anhydro-1-C- [4-chloro-3- [ [4- [ [ (3S) -tetrahydro-3-furanyl] oxy] phenyl] methyl] phenyl] -D-glucitol. Grades: Highly Purified. CAS No. 864070-44-0. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C23H27ClO7, Molecular Weight: 450.91. US Biological Life Sciences.
Worldwide
Empagliflozin
Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Synonyms: BI10773; BI-10773; BI 10773; CE0108; CS0940; PB23119; VA10802; AJ93046; Empagliflozin; trade name Jardiance. Grades: >98%. CAS No. 864070-44-0. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin 6-O-b-D-glucuronide
Empagliflozin 6-O-b-D-glucuronide is a drug metabolite within the biomedical industry, acting as an invaluable role in the research of diabetes and concomitant metabolic maladies. Demonstrating remarkable efficacy, this compound effectively impedes the functional activity of the sodium-glucose cotransporter 2 (SGLT2). Molecular formula: C29H35ClO13. Mole weight: 627.03.
Empagliflozin α Isomer
Empagliflozin α Isomer is an isomer of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Empagliflozin α-Anomer; (2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1620758-33-9. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin-d4
Empagliflozin-d 4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BI 10773-d4. CAS No. 2749293-95-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15409S.
Empagliflozin Destetrahydrofuran Impurity
An impurity of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: O-Desethyl Dapagliflozin; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: 98%. CAS No. 864070-37-1. Molecular formula: C19H21ClNO6. Mole weight: 380.83.
Empagliflozin Impurity 107
Empagliflozin Impurity 107. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-tetrahydrofuran-3-yl formate. CAS No. 167979-56-8. Molecular formula: C5H8O3. Mole weight: 116.12. Catalog: APB167979568.
Empagliflozin Impurity 141
Empagliflozin Impurity 141. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dibromo-5-chlorobenzoic acid. CAS No. 150812-33-2. Molecular formula: C7H3Br2ClO2. Mole weight: 314.36. Catalog: APB150812332.
Empagliflozin Impurity 17
An impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol; Tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl). CAS No. 2452301-27-6. Molecular formula: C23H28O7. Mole weight: 416.46.
Empagliflozin Methyl Acetate is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: ((2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl Acetate. CAS No. 2452301-09-4. Molecular formula: C25H29ClO8. Mole weight: 492.95.
Empagliflozin Ortho Isomer
Empagliflozin Ortho Isomer is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2452301-30-1. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin R-Furanose
Empagliflozin R-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Canagliflozine Furanose Impurity; (2R,3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-31-7. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin S-Furanose
Empagliflozin S-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Jardiance Impurity C; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-32-8. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Empagliflozin Tetraacetoxy
Empagliflozin Tetraacetoxy is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl Triacetate. CAS No. 1620758-21-5. Molecular formula: C32H37ClO12. Mole weight: 649.08.
Empasiprubart
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2 , preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ARGX-117. CAS No. 2579031-19-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990025.
Empedopeptin
Empedopeptin is produced by the strain of Empedobacter haloabium G393-B445. It has anti-gram-negative bacterial activity. Synonyms: Antibiotic BMY 28117; Antibiotic BU2517. CAS No. 87551-98-2. Molecular formula: C49H79N11O19. Mole weight: 1126.22.
Empesertib
Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC 50 of < 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1161909. CAS No. 1443763-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12858.
Empty Gelatin Capsules Shells
Empty Gelatin Capsules Shells. Product ID: PE-0166. Category: Capsule Excipients; Capsules Shells. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Capsule Excipients; Capsules Shells; Empty Gelatin Capsules Shells; PE-0166. Appearance: Transparent, Single Light, Double Light Capsule. Storage: Normally, hard gelatin capsules contain 13-16% of moisture. If additional moisture is absorbed when stored in a high relative humidity environment, hard gelatin capsule shell may lose their rigid shape and become distorted. In an opposite environment of extreme dryness, capsules may become too brittle and may crumble during handling. So, Capsules are to be stored under control conditions of Temperature (20-25°C) & Humidity (45-55 %).
Emraclidine
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator (WO2018002760, compound 11). Emraclidine can be used for the research of neurological diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVL-231. CAS No. 2170722-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132812.
Emraclidine
Emraclidine is a muscarinic M4 receptor positive allosteric modulator. Synonyms: 1-(2,4-dimethyl-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-2-{1-[2-(trifluoromethyl)pyridin-4-yl]azetidin-3-yl}ethan-1-one. CAS No. 2170722-84-4. Molecular formula: C20H21F3N4O. Mole weight: 390.41.
Emricasan is a pan-caspase inhibitor with antiapoptotic and antiinflammatory activity. It was shown that emricasan decreased caspase activity, serum alanine aminotransferase (ALT), and hepatic fibrogenesis in a murine model of non-alcoholic steatohepatitis. Emricasan has been granted fast track designation by the FDA for the treatment of non-alcoholic steatohepatitis cirrhosis. Uses: Liver disease therapy. Synonyms: IDN-6556; IDN6556; IDN 6556; PF 03491390; PF-03491390; PF03491390; (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid. Grades: 99.59%. CAS No. 254750-02-2. Molecular formula: C26H27F4N3O7. Mole weight: 569.51.
Emricasan
Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV) -induced increases in caspase-3 activity and protected human cortical neural progenitors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF 03491390; IDN-6556. CAS No. 254750-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10396.
Emrusolmin
Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anle138b. CAS No. 882697-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101855.
EMT inhibitor-1
EMT inhibitor-1 is a Hippo, TGF-β and Wnt signaling pathway inhibitor with anti-tumor activity. Grades: ≥98% by HPLC. CAS No. 1638526-21-2. Molecular formula: C12H12Cl2N2O2S. Mole weight: 319.2.
Emtricitabine
4-amino-5-fluoro-1-[2-(hydroxymethyl)- 1,3-oxathiolan-5-yl]- pyrimidin-2-one. aldosterone antagonist used as an adjunct in the management of chronic heart failure. CAS No. 143491-57-0. Product ID: 8-01765. Molecular formula: C8H10FN3O3S. Mole weight: 247.25.
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SM-Q;4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone;(-)-BETA-2,3-DIDEOXY-5-FLUORO-3-THIACYTIDINE;EMTRICITABINE;EMTRITABINE;FTC;FUMITREMORGIN C;EMTRICITABIN. Product Category: Inhibitors. CAS No. 143491-57-0. Molecular formula: C8H10FN3O3S. Mole weight: 247.25. Purity: 0.9994. Product ID: ACM143491570. Alfa Chemistry ISO 9001:2015 Certified.
Emtricitabine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, Emtriva, (-)-Emtricitabine, 524W91, (-)-FTC, Emtricitabine, BW 524W91,2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., Coviracil, (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine, (-)-FTC, BW 1592, (-)-2'-Deoxy-5-fluoro-3'-thiacytidine, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-.
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor ( NRTI ) with an EC 50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Group: Natural products. Alternative Names: BW1592. CAS No. 143491-57-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17427.
Emtricitabine-13C,15N2
A labeled reverse transcriptase inhibitor. A nucleoside analog structurally related too lamivudine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C713C2H10FN15N2O3S, Molecular Weight: 250.23. US Biological Life Sciences.
Worldwide
Emtricitabine 5-O-Sulfate
Emtricitabine 5-O-Sulfate is a metabolite of Emtricitabine, a reverse transcriptase inhibitor and an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. Synonyms: 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone 5-O-Sulfate; (-)-2',3'-Dideoxy-5-fluoro-3'--thiacytidine 5-O-Sulfate; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine 5-O-Sulfate; BW 1592 5-O-Sulfate; BW 524W91 5-O-Sulfate; Coviracil 5-O-Sulfate; Emtriva 5-O-Sulfate; (-)-FTC 5-O-Sulfate. Molecular formula: C8H10FN3O6S2. Mole weight: 327.31.
Emtricitabine 5-O-Sulfate-13C,15N2
Emtricitabine 5-O-Sulfate-13C,15N2 is the isotope labelled analog of Emtricitabine 5-O-Sulfate; a metabolite of Emtricitabine which is a reverse transcriptase inhibitor and an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. Synonyms: 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone 5-O-Sulfate-13C,15N2; (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine 5-O-Sulfate-13C,15N2; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine 5-O-Sulfate-13C,15N2; BW 1592 5-O-Sulfate-13C,15N2; BW 524W91 5-O-Sulfate-13C,15N2; Coviracil 5-O-Sulfate-13C,15N2; Emtriva 5-O-Sulfate-13C,15N2; (-)-FTC 5-O-Sulfate-13C,15N2. Molecular formula: C7[13C]H10FN[15N]2O6S2. Mole weight: 330.29.
Emtricitabine 6'-Disulfide
An impurity of Emtricitabine synthesis. Synonyms: (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine 6'-Disulfide; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine 6'-Disulfide. Grades: 95%. Molecular formula: C16H18F2N6O4S4. Mole weight: 524.6.
Emtricitabine 6-Disulfide
An impurity of Emtricitabine synthesis. Group: Biochemicals. Alternative Names: (-)-2,3-Dideoxy-5-fluoro-3-thiacytidine 6-Disulfide; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine 6-Disulfide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Emtricitabine Carboxylic Acid
Emtricitabine Carboxylic Acid is an impurity of the antiviral agent Emtricitabine. Group: Biochemicals. Alternative Names: (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid. Grades: Highly Purified. CAS No. 1238210-10-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Emtricitabine Carboxylic Acid
Emtricitabine Carboxylic Acid is an impurity of the antiviral agent Emtricitabine. Synonyms: (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid. Grades: > 95%. CAS No. 1238210-10-0. Molecular formula: C8H8FN3O4S. Mole weight: 261.23.
Emtricitabine Diphosphate Triethylammonium Salt
Emtricitabine Diphosphate Triethylammonium Salt is a metabolite of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: (2R-cis)-Mono[[5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Diphosphoric Acid Triethylammonium Salt; 1,3-Oxathiolane, Diphosphoric Acid Deriv. Triethylammonium Salt. Grades: 90%. Molecular formula: C8H12FN3O9P2S.xC6H15N. Mole weight: 407.21 (free acid).
Emtricitabine Enantiomer
A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. Synonyms: 4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (2S-cis)-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone. Grades: > 95%. CAS No. 137530-41-7. Molecular formula: C8H10FN3O3S. Mole weight: 247.25.
Emtricitabine Glycosamine
Emtricitabine Glycosamine is an impurity of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Molecular formula: C20H30FN3O13S. Mole weight: 571.53.