A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52.
Elsinochrome C
It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54.
Elsinochrome D
It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52.
Elsulfavirine
Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of human immunodeficiency virus (HIV) infections. It is the prodrug of the active compound VM-1500A, a small molecule selective NNRTI, which prevents HIV replication. In June 2017, elsulfavirine received its first global approval in Russia for the treatment of HIV-1 infections in combination with other antiretroviral medicines. Other formulations of this drug are also being evaluated in preclinical and phase II studies for the treatment of HIV infections and/or pre-exposure and post-exposure prophylaxis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elsulfavirine; Elpida. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 868046-19-9. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. Purity: >98%. IUPACName: N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide. Canonical SMILES: CCC(NS(=O)(C1=CC=C(NC(CC2=CC=C(Br)C(OC3=CC(C#N)=CC(Cl)=C3)=C2F)=O)C(Cl)=C1)=O)=O. Product ID: ACM868046199. Alfa Chemistry ISO 9001:2015 Certified.
Elsulfavirine
Elsulfavirine is a reverse transcriptase inhibitors for HIV-1 infection and is a new anti-HIV agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-1206. CAS No. 868046-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109056.
Eltanexor
Eltanexor (KPT-8602) is an investigational second-generation SINE compound. Eltanexor acts as an orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20-211?nM in 10 AML lines after 3 days exposure. Synonyms: KPT-8602; ONO-7706; ATG-016. Grades: ≥98%. CAS No. 1642300-52-4. Molecular formula: C17H10F6N6O. Mole weight: 428.29.
Eltanexor
Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export ( EC 50 =60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-8602. CAS No. 1642300-52-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100423.
Eltenac
A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid; Telzenac; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. CAS No. 72895-88-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Eltenac-13C,d3
Labeled Eltenac. A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid-13C,d3; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid-13C,d3; Telzenac-13C,d3; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Eltoprazine
Eltoprazine belongs the phenylpiperazine class which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It is closely related to fluprazine and batoprazine, which are similarly acting drugs. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It was found to (synergistically) potentiate the antidyskinetic effect of amantadine. It has been shown to reduce 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine;DU-28853;DU28853. Grades: >98 %. CAS No. 98224-03-4. Molecular formula: C12H16N2O2. Mole weight: 220.27.
Eltoprazine hydrochloride
Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU 28853 hydrochloride. CAS No. 98206-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16687A.
Eltoprazine hydrochloride
Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine hydrochloride has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, monohydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;DU-28853 hydrochloride;DU28853 hydrochloride. Grades: >98 %. CAS No. 98206-09-8. Molecular formula: C12H17N2O2Cl. Mole weight: 256.73.
Eltoprazine hydrochloride
Eltoprazine hydrochloride. Group: Biochemicals. Alternative Names: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride; DU 28853; DU 28893. Grades: Highly Purified. CAS No. 98206-09-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H17ClN2O2. US Biological Life Sciences.
Worldwide
Eltrombopag
Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eltrombopag;3-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid;(1,1-Biphenyl)-3-carboxylic acid, 3-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2-hydroxy-;Eltrombopag [inn];Promacta;Sb497115;Sb-497115;Unii-S56D65xj9g. Product Category: Inhibitors. Appearance: Solid. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47. Purity: 0.9973. Canonical SMILES: O=C(C1=CC(C2=CC=CC(N/N=C3C(C)=NN(C4=CC=C(C)C(C)=C4)C/3=O)=C2O)=CC=C1)O. Density: 1.33. Product ID: ACM496775612. Alfa Chemistry ISO 9001:2015 Certified.
Eltrombopag
Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-497115. CAS No. 496775-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306.
Eltrombopag
Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). Uses: Nonpeptide thrombopoietin receptor agonist. Synonyms: SB-497115-GR, SB497115. Grades: >98%. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47.
Eltrombopag
An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia. Group: Biochemicals. Alternative Names: 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB 497115. Grades: Highly Purified. CAS No. 496775-61-2. Pack Sizes: 10mg. US Biological Life Sciences.
Eltrombopag- 13 C 4 (SB-497115- 13 C 4 ) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus ( Staphylococcus aureus ) and can induce apoptosis ( apoptosis ) in liver cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SB-497115- 13 C4. CAS No. 1217230-31-3. Pack Sizes: 1 mg. Product ID: HY-15306S.
Eltrombopag Acyl Glucuronide
Eltrombopag Amide
Eltrombopag Amide is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: > 95%. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48.
Eltrombopag Amide
Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences.
Worldwide
Eltrombopag Ethyl Ester
Eltrombopag Ethyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C27H26N4O4, Molecular Weight: 470.52. US Biological Life Sciences.
Worldwide
Eltrombopag Glucuronide
Eltrombopag Glucuronide. Group: Biochemicals. Alternative Names: 1-[3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene-3-14C]hydrazinyl]-2'-hydroxy[1,1'-biphenyl]-3-carboxylate]- β-D-glucopyranuronic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C31H30N4O10, Molecular Weight: 618.59. US Biological Life Sciences.
Worldwide
Eltrombopag Impurity 5
Eltrombopag Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxamide. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48. Catalog: APB1246929021.
Eltrombopag Impurity 58
Eltrombopag Impurity 58. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-methyl 3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate. CAS No. 1246929-01-0. Molecular formula: C26H24N4O4. Mole weight: 456.49. Catalog: APB1246929010.
Eltrombopag Methyl Ester
Eltrombopag Methyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1246929-01-0. Pack Sizes: 5mg. Molecular Formula: C26H24N4O4, Molecular Weight: 456.49. US Biological Life Sciences.
Worldwide
Eltrombopag Methyl Ester
Eltrombopag Methyl Ester is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 1246929-01-0. Molecular formula: C26H24N4O4. Mole weight: 456.49.
Eltrombopag Olamine
Eltrombopag is a is an agonist of the c-mpl (TpoR) receptor used as treatment for thrombocytopenia.It has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). Uses: C-mpl agonist. Synonyms: SB-497115-GR; 2-mainoethan-1-ol hemi((Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate). Grades: ≥98%. CAS No. 496775-62-3. Molecular formula: C29H36N6O6. Mole weight: 564.64.
Eltrombopag Olamine
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eltrombopag diethanolamine salt; SB-497115GR. CAS No. 496775-62-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306A.
Elubrixin
Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist. It is potentially useful for Inflammatory bowel disease therapies. It inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. It may be an effective agent in neutrophil-predominant diseases. It was developed by GlaxoSmithKline and was in clinic phase 2 trials, but now it is terminated. Uses: Elubrixin is potentially useful for inflammatory bowel disease therapies. it may be an effective agent in neutrophil-predominant diseases. Synonyms: 1-(2-Chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea;SB-656933;SB656933;SB-656933-AAF;SB-656933-AAA;SB656933AAA;SB656933AAF;1-(4-Chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea. Grades: 98%. CAS No. 688763-64-6. Molecular formula: C17H17Cl2FN4O4S. Mole weight: 463.30.
Elubrixin tosylate
Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( IC 50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-656933 tosylate. CAS No. 960495-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18263C.
Elunonavir
Elunonavir is an antiviral. Synonyms: dimethyl (3S,8S,9S,12S)-6-({4-[1-(difluoromethyl)-1H-pyrazol-3-yl]-2,6-difluorophenyl}methyl)-8-hydroxy-9-{[4-({2-[8-(oxetan-3-yl)-3,8-diazabicyclo[3.2.1]octan-3-yl]pyrimidin-5-yl}ethynyl)phenyl]methyl}-4,11-dioxo-3,12-bis(1,1,1-trifluoro-2-methylpropan-2-yl)-2,5,6,10,13-pentaazatetradecane-1,14-dioate; methyl ((5S,8S,9S,14S)-11-(4-(1-(difluoromethyl)-1H-pyrazol-3-yl)-2,6-difluorobenzyl)-16,16,16-trifluoro-9-hydroxy-15,15-dimethyl-8-(4-((2-(8-(oxetan-3-yl)-3,8-diazabicyclo[3.2.1]octan-3-yl)pyrimidin-5-yl)ethynyl)benzyl)-3,6,13-trioxo-5-(1,1,1-trifluoro-2-methylpropan-2-yl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 2242428-57-3. Molecular formula: C52H59F10N11O8. Mole weight: 1156.09.
Elvitegravir is an HIV-1 integrase strand transfer inhibitor (INSTI) for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Anti-retroviral agents. Synonyms: GS-9137; GS 9137; GS9137; JTK-303; JTK 303; JTK303; EVG; D06677; D 06677; D-06677. Grades: ≥98%. CAS No. 697761-98-1. Molecular formula: C23H23ClFNO5. Mole weight: 447.88.
Elvitegravir
A novel inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Alternative Names: 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic Acid; GS 9137; JTK 303. Grades: Highly Purified. CAS No. 697761-98-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Elvitegravir
Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1 IIIB , HIV-2 EHO and HIV-2 ROD with IC 50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9137; JTK-303; D06677. CAS No. 697761-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14740.
Elvitegravir, 7-Desmethoxy-7-fluoro
Elvitegravir derivative. Group: Biochemicals. Alternative Names: 6-(3-Chloro-2-fluorobenzyl)-7-fluoro-1-[(S)-1-hydroxymethyl-2-methylpropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 6-[(3-Chloro-2-fluorophenyl)methyl]-7-fluoro-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-4-oxo-3-quinolinecarboxylic Acid. Grades: Highly Purified. CAS No. 869893-92-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Elvitegravir-d6 (Major)
A novel labeled inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Alternative Names: 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic Acid. Grades: Highly Purified. CAS No. 1131640-69-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Elzasonan
Elzasonan is a selective 5-hydroxytryptamine 1B receptor antagonist that was developed by Pfizer (and then later discontinued in 2008) to treat patients with major depressive disorder and obsessive compulsive disorder. Group: Biochemicals. Grades: Highly Purified. CAS No. 361343-19-3. Pack Sizes: 50mg, 500mg. Molecular Formula: C22H23Cl2N3OS, Molecular Weight: 448.41. US Biological Life Sciences.
Worldwide
Elzasonan citrate
Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder. Uses: Serotonin 1b receptor antagonists; serotonin 1d receptor antagonists. Synonyms: (2Z)-4-(3,4-dichlorophenyl)-2-[[2-(4-methylpiperazin-1-yl)phenyl]methylidene]thiomorpholin-3-one;2-hydroxypropane-1,2,3-tricarboxylic acid. Grades: ≥98%. CAS No. 361343-20-6. Molecular formula: C28H31Cl2N3O8S. Mole weight: 640.53.
Elzasonan hydrochloride
Elzasonan, also called as CP 448187, exhibits potent and selective antagonism of 5-HT1B receptors in vitro, and preclinical in vivo studies demonstrate enhanced 5-HT neurotransmission. Elzasonan is able to improve signaling to limbic regions like the hippocampus and prefrontal cortex and ultimately resulting in antidepressant effects. Synonyms: (2Z)-4-(3,4-dichlorophenyl)-2-[[2-(4-methylpiperazin-1-yl)phenyl]methylidene]thiomorpholin-3-one;hydrochloride; Elzasonan hydrochloride; Elzasonan HCl; UNII-X38F62RR8L. Grades: >98%. CAS No. 220322-05-4. Molecular formula: C22H24Cl3N3OS. Mole weight: 484.86.
Elzovantinib
Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC , MET and c-FMS , with IC 50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TPX-0022; CSF1R-IN-2. CAS No. 2271119-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111787.
EM2487 is produced by the strain of Streptomyces sp. Mer-2487. It inhibited HLV-1 replication in both chronically and acutely infected cells. The action occurs during the post-integration phase of the HIV-1 provirus DNA in the HIV-1 replication cycle. Molecular formula: C32H57N5O16P2. Mole weight: 829.76.
EM574
EM574 is an agonist of motilin receptor with an IC50 value of 6.17 nM which binds to rabbit gastric antral smooth muscle homogenates in a radioligand binding assay. Synonyms: Idremcinal; 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin. Grades: ≥98%. CAS No. 110480-13-2. Molecular formula: C39H69NO12. Mole weight: 743.96.
EM574
Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). Group: Biochemicals. Grades: Highly Purified. CAS No. 110480-13-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C39H69NO12. US Biological Life Sciences.
Worldwide
EMA401
EMA401 is an orally bioavailable, potent and highly selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures. Synonyms: EMA 401; EMA-401; Olodanrigan; (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid. Grades: ≥ 95 %. CAS No. 1316755-16-4. Molecular formula: C32H29NO5. Mole weight: 507.6.
Emactuzumab
Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with K i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 7155; RO 5509554. CAS No. 1448221-67-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99245.
Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation property. Synonyms: (4''R)-4''-Deoxy-4''-(methylamino)avermectin B1; emamectin B1a. CAS No. 119791-41-2. Molecular formula: C49H75NO13. Mole weight: 886.133.
Emamectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grades: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12.
Emamectin B1b
It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grades: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09.
Emamectin Benzoate
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric ( GABA ) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-244. CAS No. 155569-91-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0837.
Emamectin Benzoate
Emamectin Benzoate is the Emamectin derivative. Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation properties. Uses: Antiparasitic agents. Synonyms: Proclaim; Proclaim 5SG; Denim; Methylamino abamectin benzoate; Shot Wan; Denim (pesticide); Sch 58854; MK 244. Grades: > 95%. CAS No. 155569-91-8. Molecular formula: C56H81NO15. Mole weight: 1008.24.
Emamectin Benzoate
A mixture of semi-synthetic Avermectins. Exists as the anhydrous and various hydrated forms having different crystal morphologies. Insecticide. Group: Biochemicals. Alternative Names: 4''-Deoxy-4''-epi-N- (methylamino) avermectin B1 Benzoate; MK 244; Methylamino abamectin benzoate; Proclaim; Proclaim 5SG; Sch 58854; Shot-Wan; Slice. Grades: Highly Purified. CAS No. 155569-91-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Emamectin Benzoate
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate. Uses: Emamectin benzoate is usually found as a mixture of two forms, which is a cream coloured powder. it is non corrosive and stable, except that it is flammable and may explode in the presence of strong oxidising agents. emamectin benzoate is a pesticide which works by interfering with nerve impulses in the body. it is used in agricultural settings to control insects amongst vegetable crops such as ca. Product Category: Inhibitors. Appearance: white to off-white yellowish powder. CAS No. 155569-91-8. Molecular formula: C56H81NO15 (emamectin B1a benzoate) + C55H79NO15 (emamectin B1b benzoate). Mole weight: 1008.24. Purity: 0.95. Canonical SMILES: C[C@H]1O[C@@H](O[C@@]2([H])[C@H](C)O[C@@H](O[C@]([C@@H](C)/C=C/C=C3CO[C@@]4([H])[C@]\3(O)[C@H]5C=C(C)[C@H]4O)([H])/C(C)=C/C[C@@H]6C[C@H](OC5=O)C[C@]7(C=C[C@H](C)[C@@H](C(C)C)O7)O6)C[C@@H]2OC)C[C@@H](OC)[C@@H]1NC.C[C@H]8O[C@@H](O[C@@]9([H])[C@H](C)O[C@@H](O[C@]([C@@H](C)/C=C/C=C%10CO[C@@]%11([H])[C@]\%
Emamectine Benzoate
Emamectine Benzoate. Group: Biochemicals. Grades: Highly Purified. CAS No. 155569-91-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Emapalumab
Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-&gamma. Emapalumab binds with high affinity ( K d = 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NI-0501. CAS No. 1709815-23-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99191.
Emapalumab
Emapalumab is an anti-interferon-gamma (IFNγ) monoclonal antibody approved for the treatment of primary hemophagocytic lymphohistiocytosis (HLH). Synonyms: Gamifant; NI-0501; NI 0501; NI0501. CAS No. 1709815-23-5.
EMAP II human
recombinant, expressed in E. coli, ?98% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Emapunil
Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects. Synonyms: AC-5216; AC 5216; AC5216; XBD-173; XBD 173; XBD173; Emapunil. Grades: >98%. CAS No. 226954-04-7. Molecular formula: C23H23N5O2. Mole weight: 401.46.
Emapunil (AC-5216, XBD-173)
Emapunil (AC-5216, XBD-173) is a translocator protein, TSPO 18kD ligand. Group: Biochemicals. Alternative Names: N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)acetamide. Grades: Highly Purified. CAS No. 226954-04-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Emavusertib
Emavusertib is an orally active inhibitor for IRAK4 ( IC 50 =57 nM) and FLT3. Emavusertib inhibits NF-κB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib exhibits antitumor activity in mouse model. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CA-4948. CAS No. 1801344-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135317.
Emavusertib
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor activity. CA-4948 demonstrated good cellular activity in ABC DLBCL and AML cell lines. CA-4948 demonstrated moderate to high selectivity in a panel of 329 kinases as well as exhibited desirable ADME and PK profiles including good oral bioavailability in mice, rat, and dog and showed >90% tumor growth inhibition in relevant tumor models with excellent correlation with in vivo PD modulation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CA-4948; CA 4948; CA4948; Emavusertib. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1801344-14-8. Molecular formula: C24H25N7O5. Mole weight: 491.51. Purity: >98%. IUPACName: (R)-N-(5-(3-hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide. Canonical SMILES: O=C(C1=COC(C2=CC(C)=NC=C2)=N1)NC3=C(N4C[C@H](O)CC4)N=C5C(OC(N6CCOCC6)=N5)=C3. Product ID: ACM1801344148. Alfa Chemistry ISO 9001:2015 Certified.
Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embelin also displays contraceptive and pro-apoptotic properties. Group: Biochemicals. Alternative Names: 2,5-Dihydroxy-3-undecyl-p-benzoquinone; 2,5-Dihydroxy-3-undecyl-1,4-benzoquinone; Embelic acid; Emberine; NSC 91874; 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione. Grades: Highly Purified. CAS No. 550-24-3. Pack Sizes: 25mg. US Biological Life Sciences.