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| Product | Description | |
|---|---|---|
| EI-1941-2 | It is originally isolated from Farrowia sp. E-1941. EI-1941-2 inhibited recombinant human ICE with an IC50 of 0.006 μmol/L. It also inhibits elastase and cathepsin. CAS No. 189828-32-8. Molecular formula: C12H14O5. Mole weight: 238.24. |  |
| EI-2128-1 | EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus. Synonyms: (2E)-N-[(1R,3S,4'S,5R,5'R,7S)-5'-Hydroxy-6-oxodihydro-3'H-spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'-furan]-4'-yl]-4,6-dimethyl-2-dodecenamide. Molecular formula: C23H35NO6. Mole weight: 421.53. | |
| EI-2346 | EI-2346 is originally isolated from Streptomyces sp. E-2346. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 3.9 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 3,10-Dihydroxy-8-[5-hydroxy-4-(hydroxymethyl)-1,3-dioxan-2-yl]-3-methyl-1-propyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione. Molecular formula: C22H26O9. Mole weight: 434.44. | |
| Eicosafluorononane | Eicosafluorononane. Group: Biochemicals. Alternative Names: Perfluorononane. Grades: Highly Purified. CAS No. 375-96-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. |  Worldwide |
| Eicosane 99% | Eicosane 99%. CAS No. 112-95-8. VIGON Item # 500981. Categories: Speciality Ingrdients Suppliers. |  America & Internationally |
| Eicosanedioic acid | Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis. Uses: Scientific research. Group: Natural products. CAS No. 2424-92-2. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W034595. |  |
| Eicosanedioic acid dimethyl ester | Eicosanedioic acid dimethyl ester. Group: Plastic additives. Alternative Names: DIMETHYL ICOSANEDIOATE; DIMETHYL EICOSANEDIOATE; EICOSANEDIOIC ACID DIMETHYL ESTER; EICOSANEDIOIC ACID DIMETHYL ESTER 95+%; Icosanedioic acid dimethyl ester. CAS No. 42235-38-1. Product ID: dimethyl icosanedioate. Molecular formula: 370.57. Mole weight: C22< / sub>H42< / sub>O4< / sub>. COC(=O)CCCCCCCCCCCCCCCCCCC(=O)OC. PODMJVMUYCFFMK-UHFFFAOYSA-N. 96%. |  |
| Eicosanoic acid | Liquid; OtherSolid;Solid. Group: Solubility enhancing reagents. Alternative Names: Arachidic acid. CAS No. 506-30-9. Product ID: icosanoic acid. Molecular formula: 312.53. Mole weight: C20H40O2. CCCCCCCCCCCCCCCCCCCC(=O)O. InChI= 1S / C20H40O2 / c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15- 16-17-18-19-20 (21) 22 / h2-19H2, 1H3, (H, 21, 22). VKOBVWXKNCXXDE-UHFFFAOYSA-N. 99%+. | |
| Eicosanoic-d39 Acid | 98 atom % D, 97% (CP). Group: Fluorescence/luminescence spectroscopy. |  |
| Eicosanol | Eicosanol. Group: Solubility enhancing reagents. Alternative Names: Arachidic alcohol. CAS No. 629-96-9. Product ID: icosan-1-ol. Molecular formula: 298.52. Mole weight: C20H42O. CCCCCCCCCCCCCCCCCCCCO. BTFJIXJJCSYFAL-UHFFFAOYSA-N. 99%+. | |
| Eicosapentaenoic acid | Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences. | Worldwide |
| Eicosapentaenoic Acid | Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA; Timnodonic acid. CAS No. 10417-94-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0660. | |
| Eicosapentaenoic Acid | Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grades: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46. | |
| Eicosapentaenoic Acid-d5 | Eicosapentaenoic Acid-d 5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: EPA-d5; Timnodonic acid-d5. CAS No. 1197205-73-4. Pack Sizes: 1 mg (1.63 mM * 2 mL in Ethanol). Product ID: HY-B0660S. | |
| Eicosapentaenoic acid ethyl ester | Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0747. | |
| Eicosapentaenoic acid ethyl ester | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsbuilding blockseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Vascepa, AMR 101, Epadel S 300, Ethyl eicosapentaenoate, Ethyl eicosapentanoate, Timnodonic acid ethyl ester, Icosapent ethyl, 5,8,11,14,17-Eicosapentaenoic acid, ethyl ester, (all-Z)-, (all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl ester, Epadel,(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl ester, Ethyl all-cis-5,8,11,14,17-eicosapentaenoate, cis-Eicosapentaenoic acid ethyl ester, Incromega EPA. | |
| Eicosapentaenoic Acid Ethyl Ester | Eicosapentaenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: EPA 90E; Incromega E 7010. Grades: Highly Purified. CAS No. 73310-10-8. Pack Sizes: 100mg. Molecular Formula: C22H34O2, Molecular Weight: 330.5. US Biological Life Sciences. | Worldwide |
| Eicosapentaenoic Acid Impurity10 | Eicosapentaenoic Acid Impurity10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123940-93-2. Molecular formula: C22H36O2. Mole weight: 332.53. Catalog: APB123940932. | |
| Eicosapentaenoic Acid Impurity5 | Eicosapentaenoic Acid Impurity5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 140670-40-2. Molecular formula: C25H38O4. Mole weight: 402.58. Catalog: APB140670402. | |
| Eicosapentaenoic Acid Impurity6 | Eicosapentaenoic Acid Impurity6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124538-05-2. Molecular formula: C47H68O5. Mole weight: 713.06. Catalog: APB124538052. | |
| Eicosapentaenoic acid methyl ester | Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis) [1]. Uses: Scientific research. Group: Natural products. CAS No. 2734-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011311. | |
| Eicosapentaenoyl ethanolamide | 5 mg/mL in absolute ethanol, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Eicosatetraynoic acid | Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase ( ID 50 =8 μM and 4 μM, respectively) [1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM [2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro [3]. Eicosatetraynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETYA. CAS No. 1191-85-1. Pack Sizes: 1 mg. Product ID: HY-124108. | |
| Eicosatetraynoic Acid | ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; Octadehydroarachidonic acid. Grades: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.4. | |
| Eicosyltriethyl Ammonium bromide | Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences. | Worldwide |
| EIDD-1931 | EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033. | |
| EIDD-1931 | EIDD-1931 Inhibitor. Uses: Scientific use. Product Category: T8498. CAS No. 3258-2-4. |  |
| EIDD-1931 | EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| EIDD-2749 | EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4'-FlU; 4'-Fluorouridine. CAS No. 1613589-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146246. | |
| EIDD-2801 | EIDD-2801 derived from a N(4)-hydroxycytidine, is an orally bioavailable broad spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester. Grades: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31. | |
| EIF2AK1 (HRI), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2AK2 (252-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2AK3 (563-1115), active, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2AK4 (192-1024), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| eIF2-GTP-tRNAiMet Ternary Complex Inhibitor, BTdCPU (N,N'-diarylurea;translation Initiation Tenrary Complex Inhibitor, 1-(benzo[d][1, 2, 3]thiadiazol-6-yl)-3-(3, 4-dichlorophenyl)urea, BTdCPU, Heme-regulated Inhibitor Kinase Activator, BTdCPU) | A cell-permeable N,N'-diarylurea that acts as an inhibitor of the formation of the ternary complex of eukaryotic translation initiation factor 2 (eIF2), GTP and the initiator methionine tRNA (Met-tRNAi), a key regulatory step of translation initiation. It directly activates heme-regulated inhibitor kinase (HRI), which then phosphorylates eIF2a in cells at 10uM and in cell-free extracts dose-dependently, and thereby prevents respective ternary complex formation without elevating oxidative stress. The sensitivities of various cancer cell lines to the anti-proliferative effects of this compound are shown to correlate with the expression of HRI. Furthermore, this compound displays tumor growth inhibition in a mice xenograft model of MCF-7 human breast cancer cells at 175mg/kg, in vivo.CAS No:1257423-87-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1257423-87-2. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?OS, Molecular Weight: 339.2. US Biological Life Sciences. | Worldwide |
| eIF2-GTP-tRNAiMet Ternary Complex Inhibitor Negative Control, NCPdCPU (1-(2-chloro-5-nitrophenyl)-3-(3,4-dichlorophenyl)urea) | A negative control for eIF2-GTP-tRNAiMet ternary complex Inhibitor, BTdCPU. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| eIF-2? Inhibitor II, Sal003 - CAS 301359-91-1 | The eIF-2? Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2S1, His tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 ?M; Kd: 0.043 ?M) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095486-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101513. | |
| eIF4A3-IN-2 | eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095677-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101785. | |
| eIF4E Active human | N-terminal GST-tag, recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 | The eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, also referenced under CAS 315706-13-9, controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| eIF4E-IN-2 | eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e). eIF4E-IN-2 has the potential for researching eIF4e dependent diseases, including the research of cancer (extracted from patent WO2021003157A1, compound 1188)[1]. eIF4E-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2575840-38-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145262. | |
| EIINFEKL trifluoroacetate salt | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| EILEVPST | EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis [1]. Uses: Scientific research. Group: Peptides. CAS No. 239075-62-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3533. | |
| EIPA | EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840. | |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. | |
| EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide) | EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 1154-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. | |
| EIPA hydrochloride | EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A. | |
| EIT hydrobromide | EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08. | |
| EIT hydrobromide | EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| EL-102 | EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grades: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47. | |
| ELA | ELA is a ELABELA mutant peptide and also a negative control for ELA-32. Elabela is one of two endogenous ligands for the G-protein-coupled APLNR receptor. Molecular formula: C162H271N57O39S4. Mole weight: 3769.55. | |
| ELA-11 (human) | ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grades: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57. | |
| ELA-14 (human) | ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. | |
| ELA-14 (human) acetate | ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. | |
| ELA-14 negative control | Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93. | |
| ELA-21 (human) | ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grades: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12. | |
| ELA-32 (human) | ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grades: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8. | |
| Elacestrant | Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19822. | |
| Elacestrant | Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Synonyms: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Molecular formula: C30H38N2O2. Mole weight: 458.65. | |
| Elacestrant dihydrochloride | Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A. | |
| Elacestrant HCl | Elacestrant , also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAD1901; RAD-1901; RAD 1901; RAD1901 HCl salt; Elacestrant dihydrochloride; Elacestrant HCl. Product Category: Others. Appearance: Solid powder. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. Purity: >98%. IUPACName: (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride. Canonical SMILES: OC1=CC=C2C[C@H](C3=CC=C(OC)C=C3N(CC4=CC=C(CCNCC)C=C4)CC)CCC2=C1.[H]Cl.[H]Cl. Product ID: ACM1349723938. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Elacestrant S enantiomer | Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63. | |
| Elacestrant S enantiomer dihydrochloride | Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654. | |
| Elacridar | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. | |
| Elacridar | Elacridar. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. Appearance: Solid. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.6. Purity: 0.98. Product ID: ACM143664113. Alfa Chemistry ISO 9001:2015 Certified. | |
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