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| Product | Description | |
|---|---|---|
| Eicosyltriethyl Ammonium bromide | Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences. |  Worldwide |
| EIDD-1931 | EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033. |  |
| EIDD-1931 | EIDD-1931 Inhibitor. Uses: Scientific use. Product Category: T8498. CAS No. 3258-2-4. |  |
| EIDD-1931 | EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. |  |
| EIDD-2801 | EIDD-2801 derived from a N(4)-hydroxycytidine, is an orally bioavailable broad spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester. Grades: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31. | |
| EIF2AK1 (HRI), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| EIF2AK2 (252-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2AK3 (563-1115), active, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2AK4 (192-1024), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| eIF2-GTP-tRNAiMet Ternary Complex Inhibitor, BTdCPU (N,N'-diarylurea;translation Initiation Tenrary Complex Inhibitor, 1-(benzo[d][1, 2, 3]thiadiazol-6-yl)-3-(3, 4-dichlorophenyl)urea, BTdCPU, Heme-regulated Inhibitor Kinase Activator, BTdCPU) | A cell-permeable N,N'-diarylurea that acts as an inhibitor of the formation of the ternary complex of eukaryotic translation initiation factor 2 (eIF2), GTP and the initiator methionine tRNA (Met-tRNAi), a key regulatory step of translation initiation. It directly activates heme-regulated inhibitor kinase (HRI), which then phosphorylates eIF2a in cells at 10uM and in cell-free extracts dose-dependently, and thereby prevents respective ternary complex formation without elevating oxidative stress. The sensitivities of various cancer cell lines to the anti-proliferative effects of this compound are shown to correlate with the expression of HRI. Furthermore, this compound displays tumor growth inhibition in a mice xenograft model of MCF-7 human breast cancer cells at 175mg/kg, in vivo.CAS No:1257423-87-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 1257423-87-2. Pack Sizes: 10mg. Molecular Formula: C??H?Cl?N?OS, Molecular Weight: 339.2. US Biological Life Sciences. | Worldwide |
| eIF2-GTP-tRNAiMet Ternary Complex Inhibitor Negative Control, NCPdCPU (1-(2-chloro-5-nitrophenyl)-3-(3,4-dichlorophenyl)urea) | A negative control for eIF2-GTP-tRNAiMet ternary complex Inhibitor, BTdCPU. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| eIF-2? Inhibitor II, Sal003 - CAS 301359-91-1 | The eIF-2? Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| EIF2S1, His tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| eIF4E Active human | N-terminal GST-tag, recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 | The eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, also referenced under CAS 315706-13-9, controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| EIINFEKL trifluoroacetate salt | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| EILEVPST | EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis [1]. Uses: Scientific research. Group: Peptides. CAS No. 239075-62-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3533. | |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. | |
| EIPA | EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840. | |
| EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide) | EIPA (Ethylisopropyl Amiloride, 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 1154-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| EIPA hydrochloride | EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC 50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na + /H + -exchanger 3 ( NHE3 ). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A. | |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. | |
| EIT hydrobromide | EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08. | |
| EIT hydrobromide | EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| EL-102 | EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grades: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47. | |
| ELA | ELA is a ELABELA mutant peptide and also a negative control for ELA-32. Elabela is one of two endogenous ligands for the G-protein-coupled APLNR receptor. Molecular formula: C162H271N57O39S4. Mole weight: 3769.55. | |
| ELA-11 (human) | ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grades: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57. | |
| ELA-14 (human) | ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. | |
| ELA-14 (human) acetate | ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. | |
| ELA-14 negative control | Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93. | |
| ELA-21 (human) | ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grades: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12. | |
| ELA-32 (human) | ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grades: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8. | |
| Elacestrant | Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19822. | |
| Elacestrant | Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Synonyms: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Molecular formula: C30H38N2O2. Mole weight: 458.65. | |
| Elacestrant dihydrochloride | Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC 50 s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER + breast cancer cell lines in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A. | |
| Elacestrant HCl | Elacestrant , also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAD1901; RAD-1901; RAD 1901; RAD1901 HCl salt; Elacestrant dihydrochloride; Elacestrant HCl. Product Category: Others. Appearance: Solid powder. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. Purity: >98%. IUPACName: (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride. Canonical SMILES: OC1=CC=C2C[C@H](C3=CC=C(OC)C=C3N(CC4=CC=C(CCNCC)C=C4)CC)CCC2=C1.[H]Cl.[H]Cl. Product ID: ACM1349723938. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Elacestrant S enantiomer | Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63. | |
| Elacestrant S enantiomer dihydrochloride | Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacridar | Elacridar. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. Appearance: Solid. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.6. Purity: 0.98. Product ID: ACM143664113. Alfa Chemistry ISO 9001:2015 Certified. | |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654. | |
| Elacridar | Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences. | Worldwide |
| Elacridar | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. | |
| Elacridar-d4 (Major) | A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport. Group: Biochemicals. Alternative Names: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl-d4]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918-d4; GG 918-d4; GW 0918-d4. Grades: Highly Purified. CAS No. 1189481-51-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Elacridar hydrochloride | Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Synonyms: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10. | |
| Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride) | P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Elacytarabine | Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Synonyms: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67. | |
| Elacytarabine | Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 4055. CAS No. 188181-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14941. | |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Synonyms: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E) -1-[4- (Methylthio) phenyl]-3-[3, 5-dimethyl-4-[ (carboxydimethylmethyl) oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49. | |
| Elafibranor | Elafibranor (GFT505) is a PPARα/δ agonist with EC 50 s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16737. | |
| Elafin human | >90% (by MS, HPLC and SDS-PAGE), recombinant, expressed in Saccharomyces cerevisiae. Group: Fluorescence/luminescence spectroscopy. | |
| Elagolix | Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Synonyms: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6. | |
| Elagolix Impurity 26 | Elagolix Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092070-97-7. Molecular formula: C33H32F5N3O5. Mole weight: 645.63. Catalog: APB1092070977. | |
| Elagolix sodium | Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-56418 sodium. CAS No. 832720-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14369. | |
| Elagolix sodium | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Synonyms: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate;NBI56418 Na; NBI-56418; NBI 56418;834153-87-6 (Elagolix). Grades: 98%. CAS No. 832720-36-2. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58. | |
| Elaidamide | Elaidamide has been found in the cerebrospinal fluid of sleep-deprived cats. Elaidamide is a fatty acid amide that inhibits rat microsomal epoxide hydrolase (mEH; Ki = 70 nM) and porcine pancreatic and human synovial phospholipase A2 (PLA2). Uses: Food additives. Synonyms: Elaidoylamide; (E)-9,10-Octadecenamide; 9E-octadecenamide. Grades: ≥95%. CAS No. 4303-70-2. Molecular formula: C18H35NO. Mole weight: 281.5. | |
| Elaidic acid | Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. Uses: Scientific research. Group: Natural products. CAS No. 112-79-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-113016. | |
| Elaidic acid methyl ester | Elaidic acid methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elaidic acid methyl ester;trans-9-Octadecenoic methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 2462-84-2. Molecular formula: C19H36O2. Mole weight: 296.49. Density: 0.871 g/mL at 20 °C(lit.). Product ID: ACM2462842. Alfa Chemistry ISO 9001:2015 Certified. Categories: METHYL ELAIDATE. | |
| Elaidyl alcohol | ?99%. Group: Fluorescence/luminescence spectroscopy. | |
| Elaiomycin | It is produced by the strain of Streptomyces hepaticus. It has the activity of anti-gram-positive bacteria and negative bacteria, especially has strong effect on mycobacterium tuberculosis. It is a carcinogen. Synonyms: D-threo-4-Methoxy-3-(1-octenylazoxy)-2-butanol; D-threo-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; (2S,3S)-4-Methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, D-threo-; (E,Z)-(2S,3S)-4-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, (E,Z)-(2S,3S)-. CAS No. 23315-05-1. Molecular formula: C13H26N2O3. Mole weight: 258.36. | |
| Elaiophylin | It is produced by the strain of Streptomyces melanosporofacien. It has the activity of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as insect repellent and growth promoter for ruminants. Elaiophylin is an autophagy inhibitor, which exerts antitumor activity as a single agent in ovarian cancer cells. Synonyms: Azalomycin B; Salbomycin; Azalomycin B; Antibiotic 5001B; Antibiotic 56-62; Elaiofilin. Grades: ≥95%. CAS No. 37318-06-2. Molecular formula: C54H88O18. Mole weight: 1025.26. | |
| Elaiophylin (Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846I, Gopalamicin, Salbomycin, Azalomycin B, SNA 4606-3) | Antibiotic. Active against Gram-positive bacteria, protozoa and tumors. Testosterone 5alpha-reductase inhibitor. Nitric oxide synthase (NOS) inhibitor. Immunosuppressive and enhances the antifungal activity of rapamycin. Group: Biochemicals. Grades: Highly Purified. CAS No. 37318-06-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Elaiophyllin (Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846 I, Antibiotic SNA 4606-3, Azalomycin B, Gopalamicin, Salbomycin) | Elaiophyllin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophyllin inhibits testosterone 5-reductase. It has synergistic antifungal activity with its co-metabolite rapamycin. It has also been found to have anthelminthic and immunosuppressive activity and to inhibit nitric oxide synthesis. Elaiophyllin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumor cells. Group: Biochemicals. Alternative Names: Antibiotic 255-E, Antibiotic 5001B, Antibiotic 56-62, Antibiotic 846 I, Antibiotic SNA 4606-3, Azalomycin B, Gopalamicin, Salbomycin. Grades: Highly Purified. CAS No. 37318-06-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Elamipretide | Elamipretide (MTP-131) is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: MTP-131; RX-31; SS-31. CAS No. 736992-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0125. | |
| Elamipretide triacetate | Elamipretide triacetate is an aromatic-cationic tetrapeptide that targets the mitochondrial intima and is an inhibitor of cardiolipin peroxidase. It easily penetrates cell membranes and has been used in therapeutic trials investigating Leber's Hereditary Optic Neuropathy. Synonyms: L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-, acetate (1:3); SS-31 triacetate; H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2.3CH3CO2H; D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide acetic acid; D-Arg-2',6'-Dmt-Lys-Phe-NH2 triacetate. Grades: ≥95%. CAS No. 1849610-71-4. Molecular formula: C32H49N9O5.3C2H4O2. Mole weight: 819.95. | |
| Elasnin | Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Synonyms: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,?5-Dibutyl-6-(1-butyl-2-oxoheptyl)?-4-hydroxy-2H-pyran-2-one. Grades: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Elasnin (3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one) | Inhibitor of human leukocyte elastase (IC50=1.3ug/ml), different other elastases and chymotrypsin (IC50=82ug/ml). Group: Biochemicals. Grades: Highly Purified. CAS No. 68112-21-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Elastase | Elastase. Synonyms: EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;Elastase, pancreatic from porcine pancreas, 30 units/mg;Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free. CAS No. 39445-21-1. Pack Sizes: 1 g. Product ID: CDF4-0039. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; Elastase; CDF4-0039; 39445-21-1; 254-453-6; 39445-21-1. Purity: 0.99. Color: White. EC Number: 254-453-6. Physical State: Lyophilized Powder. Solubility: H2O: soluble. Storage: -20°C. |  |
| Elastase, Human leukocytes | Elastase, Human leukocytes is a serine protease present in the nitrogen-loving granules of neutrophils. Elastase, Human leukocytes potential substrates include almost all components of the extracellular matrix, as well as a variety of proteins such as coagulation factors, complement, immunoglobulins and cytokines. It has a strong proteolytic function and participates in the pathogenesis of inflammatory tissue damage [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9004-6-2. Pack Sizes: 1 U. Product ID: HY-P2751. | |
| Elastase, Human Neutrophil | Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans. Group: Fluorescence/luminescence spectroscopy. | |
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