A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Eleutheroside C is isolated from the root barks of Eleutherococcus senticosus. Synonyms: ethyl alpha-d-galactopyranoside. Grade: > 95%. CAS No. 15486-24-5. Molecular formula: C8H16O6. Mole weight: 208.2.
Eleutheroside D
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 79484-75-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Eleutheroside E
Eleutheroside E. Group: Biochemicals. Alternative Names: Acanthoside D; Syringaresinol-di-O-glucoside. Grades: Plant Grade. CAS No. 39432-56-9. Pack Sizes: 20mg. Molecular Formula: C34H46O18, Molecular Weight: 742.718. US Biological Life Sciences.
Worldwide
Eleutheroside E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Eleutheroside E
Eleutheroside E is an important component of ginseng that can be taken orally. Eleutheroside E has anti-inflammatory and antioxidant properties, and it helps reduce apoptosis in heart cells caused by hypoxia-reoxygenation (H/R) damage. Eleutheroside E can improve type 2 diabetes, enhance cognitive function, and has neuroprotective effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 39432-56-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0272.
Elevenostat
Elevenostat (JB3-22) is a selective HDAC11 inhibitor with an IC50 of 0.235 μM. Elevenostat can induce apoptosis of multiple myeloma cells and has anti-tumor effect. In addition, Elevenostat inhibits the maturation of mouse oocytes[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JB3-22. CAS No. 1454902-97-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145757.
Elexacaftor
Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-445. CAS No. 2216712-66-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111772.
Elexacaftor
Elexacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector used as a medication for cystic fibrosis treatment in combination with ivacaftor and tezacaftor. Synonyms: VX-445; VX445; (S)-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide. Grade: 98%. CAS No. 2216712-66-0. Molecular formula: C26H34F3N7O4S. Mole weight: 597.65.
Elezanumab
Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC 50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab). CAS No. 1791416-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99359.
ELF97 phosphate
ELF97 phosphate (ELFP) is a phosphatase substrate, which can produced a fluorescent, water-insoluble product ELF97 alcohol after hydrolysis by phosphatases. ELF97 phosphate can be utilized to study and quantify the activity of extracellular phosphatases of algae in natural water [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ELFP. CAS No. 147394-94-3. Pack Sizes: 1 mg. Product ID: HY-160973.
Elgemtumab
Elgemtumab(LJM716) is a fully human IgG monoclonal antibody. Elgemtumab can specifically bind to HER3, block ligand-dependent and independent HER3 signal transduction and cell proliferation, and has good anti-tumor potential[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LJM716. CAS No. 1512559-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99936.
EL-HPE High Performance Electrolyte
EL-HPE High Performance Electrolyte. Uses: El-hpe high performance electrolyte is a low viscosity, high ionic conductivity liquid electrolyte, and, therefore, provides highest performance. due to the low boiling point of the main solvent and the chemistry of the electrolyte mixture; el-hpe will not provide best long term stability under standard solar conditions and/or under elevated temperature testingparticularly suitable for glass or metal/glass substrate-based dsc systems. Group: Organic solar cell (opv) materials. Alternative Names: EL-HPE electrolyte,EL-HPE. Pack Sizes: 10, 50 mL in glass bottle.
EL-HSE High Stability Electrolyte
EL-HSE High Stability Electrolyte. Uses: El-hse high stability electrolyte is a low toxicity liquid electrolyte to achieve ultra-long life in normal operating conditions. this is the "work horse" electrolyte system for long term stability testing. particularly suitable for glass or metal/glass substrate-based dsc systems.outstanding stability has been achieved with el-hse, 25,600 hours of continuous light soaking at 55-60°c and 3,000 hours at 85°c. Group: Organic solar cell (opv) materials. Alternative Names: EL-HSE electrolyte,EL-HSE. Pack Sizes: 10, 50 mL in glass bottle.
EL-HTE High Temperature Electrolyte
EL-HTE High Temperature Electrolyte. Group: Organic solar cell (opv) materials.
Eliapixant
Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor , with an IC 50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1817080. CAS No. 1948229-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109170.
Eliapixant
Eliapixant is a P2X3 receptor antagonist, which is under a clinical trial for refractory chronic cough (RCC) treatment. Synonyms: BAY 1817080. CAS No. 1948229-21-7. Molecular formula: C22H21F3N4O3S. Mole weight: 478.49.
Eliglustat
Eliglustat is a glucosylceramide synthase inhibitor indicated for the long-term treatment of type 1 Gaucher disease in patients who are CYP2D6 extensive metabolizers, intermediate metabolizers , or poor metabolizers in treatment-naive and treatment-experi. Uses: Inhibits glucosylceramide synthase(gcs). Synonyms: Genz-99067; Genz 99067; Genz99067; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide. Grade: ≥98%. CAS No. 491833-29-5. Molecular formula: C23H36N2O4. Mole weight: 404.55.
Eliglustat
Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC 50 of 24 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Genz 99067. CAS No. 491833-29-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14885.
Eliglustat hemitartrate
Eliglustat hemitartrate is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Genz-112638; Eliglustat tartrate. CAS No. 928659-70-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-14885A.
Eliglustat hemitartrate
Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Synonyms: Genz-112638; Genz 112638; Genz112638; Eliglustat tartrate; Bis(N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1- ylmethyl)ethyl)octanamide) (2R,3R)-2,3-dihydroxybutanedioate; Octanamide, N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1- pyrrolidinylmethyl)ethyl)-, (2R,3R)-2,3-dihydroxybutanedioate; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide (2R,3R)-2,3-dihydroxybutanedioic acid. Grade: >98%. CAS No. 928659-70-5. Molecular formula: C50H78N4O14. Mole weight: 959.17.
Eliglustat Impurity 5
Eliglustat Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((1S,2S)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide. CAS No. 1092472-70-2. Molecular formula: C23H36N2O4. Mole weight: 404.54. Catalog: APB1092472702.
Eliglustat Impurity 6
Eliglustat Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((1S,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide. CAS No. 1092472-66-6. Molecular formula: C23H36N2O4. Mole weight: 404.54. Catalog: APB1092472666.
Elimusertib
Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC 50 of 7 nM. Elimusertib has anti-tumor activity [1] [2]. Elimusertib can be used for the research of solid tumors and lymphomas [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1895344. CAS No. 1876467-74-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101566.
Elimusertib free base
Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elimusertib, free base; BAY-1895344; BAY 1895344; BAY1895344. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1876467-74-1. Molecular formula: C20H21N7O. Mole weight: 375.44. Purity: >98%. IUPACName: (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine. Canonical SMILES: CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=CC=NN5)N=CC=C24. Product ID: ACM1876467741. Alfa Chemistry ISO 9001:2015 Certified.
Elimusertib hydrochloride
Elimusertib (BAY 1895344) hydrochloride is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib hydrochloride has anti-tumor activity[1][2]. Elimusertib hydrochloride can be used for the research of solid tumors and lymphomas[3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1895344 hydrochloride. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101566A.
Elinafide
Elinafide, an isoquinoline derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in anticancer studies. Synonyms: Elinafide; UNII-HL580335SI; Elinafide [INN]; 2-[2-[3-[2-(1,3-dioxobenzo[de]isoquinolin-2-yl)ethylamino]propylamino]ethyl]benzo[de]isoquinoline-1,3-dione; LU-79553. Grade: 98%. CAS No. 162706-37-8. Molecular formula: C31H28N4O4. Mole weight: 520.59.
Elinogrel
Elinogrel is a P2Y12 antagonist displaying antiplatelet activity. Synonyms: 5-Chloro-N-[[[4-[6-Fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide. Grade: ≥98% by HPLC. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.95.
Elinogrel
Elinogrel. Group: Biochemicals. Grades: Purified. CAS No. 936500-94-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Elinogrel
Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry ISO 9001:2015 Certified.
Elinogrel
Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y 12 antagonist ( IC 50 =20 nM). It is orally and intravenously available and has potent antiplatelet effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT060128. CAS No. 936500-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11021.
Elinzanetant is a neurokinin receptors antagonist that may help reduce the frequency and severity of hot flushes during menopause. Elinzanetant reduces Estradiol and Progesterone in Healthy Women. Synonyms: BAY 3427080; BAY-3427080; BAY3427080; NT 814; NT-814; NT814; GSK1144814A; GSK-1144814A; GSK 1144814A. Grade: 98%. CAS No. 929046-33-3. Molecular formula: C33H35F7N4O3. Mole weight: 668.66.
Elinzanetant
Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can reduce the levels of estradiol and progesterone, and is used in the study of vascular motor symptoms and sleep disorders related to menopause in women [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NT-814; BAY3427080. CAS No. 929046-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109171.
Elipovimab
Elipovimab is a potent broadly neutralizing HIV-1 antibody for the targeted elimination of HIV-infected cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2101210-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99937.
Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL-820715. CAS No. 119431-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12881.
Eliprodil
Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Synonyms: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. Grade: 95%. CAS No. 119431-25-3. Molecular formula: C20H23ClFNO. Mole weight: 347.85.
Eliprodil
Eliprodil. Group: Biochemicals. Grades: Purified. CAS No. 119431-25-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. Group: Biochemicals. Grades: Highly Purified. CAS No. 119431-25-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Elironrasib
Elironrasib is an orally active and covalent inhibitor of KRASG12C(ON). Elironrasib forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). Thus, Elironrasib prevents KRASG12C(ON) from signaling via steric blockade of RAS effector binding. Elironrasib inhibits ERK signaling and induced apoptosis in KRASG12C-mutant H358 cells. Elironrasib also inhibits the proliferation of KRASG12C mutant cells with a median IC50 of 0.11 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMC-6291. CAS No. 2641998-63-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153346.
elisabethatriene synthase
Requires Mg2+ or less efficiently Mn2+. The enzyme is also able to use farnesyl diphosphate and geranyl diphosphate. Group: Enzymes. Synonyms: elisabethatriene cyclase. Enzyme Commission Number: EC 4.2.3.41. CAS No. 334022-59-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5200; elisabethatriene synthase; EC 4.2.3.41; 334022-59-2; elisabethatriene cyclase. Cat No: EXWM-5200.
Elisartan
Elisartan, also known as HN-65021, is an orally active non-peptide prodrug of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 1-((ethoxycarbonyl)oxy)ethyl ester; HN 65021; HN-65021. CAS No. 149968-26-3. Molecular formula: C27H29ClN6O5. Mole weight: 553.01.
Elisidepsin
Elisidepsin is a marine-derived, synthetic cyclic depsipeptide with potential antineoplastic activity. Elisidepsin is a derivative of a natural marine compound that belongs to a family of dehydro aminobutyric acid-containing peptides (kahalalides) isolated from the herbivorous marine mollusk Elysia rufescens. Although the primary mechanism of action has yet to be elucidated, this agent exhibits anti-proliferative activity in a wide variety of cancer cell types, including breast, colon, pancreas, lung, and prostate; it appears to induce oncolytic rather than apoptotic cell death. Synonyms: PM-02734; N-[(4S)-4-methylhexanoyl]-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-N-{(3S,6Z,9S,12R,15R,18R,19R)-9-benzyl-15-[(2S)-butan-2-yl]-6-ethylidene-3,12-diisopropyl-19-methyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclononadecan-18-yl}-D-alloisoleucinamide. CAS No. 681272-30-0. Molecular formula: C75H124N14O16. Mole weight: 1477.90.
Elizabethin
It is produced by the strain of Streptomyces elizabethii. It has antifungal activity. CAS No. 78361-81-6. Molecular formula: C35H58O12. Mole weight: 670.83.
ELK1, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
Ellagicacid
Ellagicacid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone. Product Category: Material of cosmetics. Appearance: Yellow-brown fluid fine powder. CAS No. 476-66-4. Molecular formula: C14H6O8. Mole weight: 302.19. Product ID: ACM476664. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ellagic acid.
Ellagic acid
25g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C14H6O8. CAS No. 476-66-4. Prepack ID 23304412-25g. Molecular Weight 302.19. See USA prepack pricing.
Ellagic acid
Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits. It has been fraudulently marketed as having the ability to prevent and treat a number of human maladies, including cancer, but such claims have not been proven. Ellagic acid can be used in cosmetics material. Uses: Anti-proliferative; anti-oxidant. Synonyms: Elagostasine, Gallogen; Alizarine Yellow; Benzoaric acid; CCRIS 774; CCRIS774; CCRIS-774; HSDB 7574; HSDB7574; HSDB-7574; Lagistase. Grade: >98%. CAS No. 476-66-4. Molecular formula: C14H6O8. Mole weight: 302.19.
Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2 , with an IC 50 of 40 nM and a K i of 20 nM. Uses: Scientific research. Group: Natural products. CAS No. 476-66-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0183.
Ellagic acid
Natural Compounds; Herbal Medicinal Products Standards; Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: Reagents. CAS No. 476-66-4.
Ellagic acid
Ellagic acid - Product ID: NST-10-60. Category: Polyphenols. Alternative Names: Benzoaric acid ; 4,4',5,5',6,6'-Hexahydroxydiphenic acid. Purity: 98%. Test method: HPLC. CAS No. 476-66-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Grey to brown Powder. Molecular formula: C14H6O8. Mole weight: 302.2. Storage: +2 +8 °C.
Ellagic Acid is a phenol antioxidant found naturally in various fruits and vegetables. Ellagic Acid was shown to exhibit high levels of antiproliferative and antioxidant properties in studies, which suggests its potential health benefits following ellagic acid consumption. Group: Biochemicals. Alternative Names: Alizarin yellow; Alizarine Yellow; Benzoaric acid; C.I. 55005; C.I. 75270; Elagostasine; Eleagic acid; G 91006; Gallogen; Gallogen (astringent); LDN 0097519; Lagistase. Grades: Highly Purified. CAS No. 476-66-4. Pack Sizes: 25g. Molecular Formula: C??H?O?, Molecular Weight: 302.19. US Biological Life Sciences.
Ellagic acid dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 133039-73-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H6O8.2H2O, Molecular Weight: 338.223. US Biological Life Sciences.
Worldwide
Ellagic Acid, Dihydrate - CAS 476-66-4
A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties. Group: Fluorescence/luminescence spectroscopy.
Ellagic Acid (Hydrate)
Ellagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 314041-08-2. Molecular formula: C14H8O9. Mole weight: 320.21. Product ID: ACM314041082-1. Alfa Chemistry ISO 9001:2015 Certified.
Ellipticine
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;ELLIPTICINE;3-b)carbazole,5,11-dimethyl-6h-pyrido(;icig770;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG). Product Category: Inhibitors. CAS No. 519-23-3. Molecular formula: C17H14N2. Mole weight: 246.31. Density: 1.257±0.06 g/cm³ (20 ºC 760 Torr). Product ID: ACM519233. Alfa Chemistry ISO 9001:2015 Certified.
Ellipticine
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795. CAS No. 519-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15753.
ELLIPTICINE
Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. Ellipticine is also a natural product, isolated in 1959 from the Australian evergreen tree of the Apocynaceae family. Ellipticine was found to be an extremely promising anticancer drug. The planar polycyclic structure was found to interact with DNA through intercalation, exhibiting a high DNA binding affinity (10(6) M(-1)). The presence of protonatable ring nitrogens distinguished ellipticine from other simple intercalators. Both monocationic and uncharged species were found to be present under physiological conditions. The positive charge stabilized the binding of ellipticine to nucleic acids, while the more lipophilic uncharged compound was shown to readily penetrate membrane barriers. The structural nature of these compounds offers a plausible basis for the implication of multiple modes of action, including DNA binding, interactions with membrane barriers, oxidative bioactivation and modification of enzyme function; most notably that of topoisomerase II and telomerase. (Curr Med Chem Anticancer Agents. 2004 Mar;4(2):149-72). Synonyms: BRN 0221300; CCG-36483; CCRIS 2003; DB-052047; elliptecine; ellipticine; Elliptisine; K00071; LP00531; LS-133282; NSC 71795; NSC71795; NSC-71795; TCMDC-125546; VZ29809. Grade: 0.98. CAS No. 519-23-3. Molecular formula: C17H14N2. Mole weight: 246.31.
Ellipticine - CAS 519-23-3
A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II-mediated DNA breakage. Group: Fluorescence/luminescence spectroscopy.
Ellipticine hydrochloride
Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795 hydrochloride. CAS No. 5081-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15753A.
Ellipticine hydrochloride
Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. Ellipticine is a natural product isolated from the Australian evergreen tree of the Apocynaceae family. Synonyms: NSC 71795 hydrochloride; Ellipticine HCl; PZE. CAS No. 5081-48-1. Molecular formula: C17H15ClN2. Mole weight: 282.77.
Ellipticine (NSC 71795)
Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in target tissues. Ellipticine has been shown to inhibit the proliferation of human breast adenocarcinoma MCF-7 cells, leukemia HL-60 and CCRF-CEM cells, neuroblastoma IMR-32, UKF-NB-3, and UKF-NB-4 cells, and U87MG glioblastoma cells with IC50 values ranging from 0.27-4.7uM. Group: Biochemicals. Alternative Names: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole, NSC 71795. Grades: Highly Purified. CAS No. 519-23-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14N2, Molecular Weight: 246.3. US Biological Life Sciences.
Worldwide
Elloramycin
It is produced by the strain of Streptomyces olivaceus Tu 2353. It has weak activity against gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity. Synonyms: Elloramycin A; methyl (6aR,7S,10aR)-3-[(6-deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy]-6a,7,12-trihydroxy-8,10a-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate; (6aR)-3-[(2-O,3-O,4-O-Trimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-6,6a,7,10,10a,11-hexahydro-6aα,7α,12-trihydroxy-8,10aα-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylic acid methyl ester. CAS No. 97218-42-3. Molecular formula: C32H36O15. Mole weight: 660.62.
Antibiotic. Antibacterial. Moderate cytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 128233-09-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
ELN318463
ELN318463, a selective γ-secretase inhibitor of amyloid precursor protein (APP), has differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12 and 656 nM for PS1 and PS2, respectively. It is 51-fold more selective for PS1. Synonyms: N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-azepin-3-yl]-Benzenesulfonamide; N-(4-Bromobenzyl)-4-chloro-N-[(3R)-2-oxo-3-azepanyl]benzenesulfonamide; Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-azepin-3-yl]-. Grade: ≥98%. CAS No. 851600-86-7. Molecular formula: C19H20BrClN2O3S. Mole weight: 471.80.
ELN318463 racemate
ELN318463 racemate is the racemate of ELN318463, which is a selective γ-secretase inhibitor of amyloid precursor protein (APP). Synonyms: Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-(hexahydro-2-oxo-1H-azepin-3-yl)-; N-(4-Bromobenzyl)-4-chloro-N-(2-oxo-3-azepanyl)benzenesulfonamide. Grade: ≥90%. CAS No. 851599-82-1. Molecular formula: C19H20BrClN2O3S. Mole weight: 471.80.
ELN 441958
ELN441958 is a novel, potent and selective bradykinin B1 receptor antagonist with Ki value of 0.26 nM. It competitively inhibited the binding of the agonist [3H]DAKD to the human B1 receptor in IMR-90 lung fibroblast cell membranes. It is highly selective for B1 over B2 receptors and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor. It also inhibited human μ-, δ-, κ- opioid receptors and muscarinic M1 receptor with Ki values of 0.13, 0.69, 1.5 and 0.37 μM, respectively. It exhibited good permeability and metabolic stability in vitro. It exhibited high oral bioavailability and moderate plasma half-lives in rats and rhesus monkeys. It does not inhibit the activation of the human bradykinin B2 receptor at concentrations up to 10 μM. It has a moderate clearance and volume of distribution in both species following i.v. administration, consistent with the high metabolic stability in rat, rhesus, and human microsomes. Uses: Eln441958 exhibited high oral bioavailability and moderate plasma half-lives. Synonyms: ELN441958; ELN 441958; ELN-441958; 7-Chloro-2-[3-[[9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl]carbonyl]phenyl]-2,3-dihydroisoindol-1-one. Grade: >98%. CAS No. 913064-47-8. Molecular formula: C29H29ClN4O2. Mole weight: 501.02.