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| Product | Description | |
|---|---|---|
| Emicerfont | Emicerfont is a Corticotropin releasing factor receptor 1 antagonist. It can block the CRF1 receptor and so reduce ACTH release. It has been investigated for the treatment of irritable bowel syndrome (IBS) and alcoholism. In Feb 2008, GlaxoSmithKline completed enrolment in its Phase-II trial for Irritable bowel syndrome in the US and Canada. Uses: Irritable bowel syndrome (ibs) and alcoholism. Synonyms: GW876008; 1-{1-[1-(4-Methoxy-2-methylphenyl)-6-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}imidazolidin-2-one; GW876008X; 2-Imidazolidinone, 1-[1-[2,3-dihydro-1-(4-methoxy-2-methylphenyl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl]-. Grade: 98%. CAS No. 786701-13-1. Molecular formula: C22H24N6O2. Mole weight: 404.47. |  |
| Emicerfont | Emicerfont is a corticotropin-releasing factor type 1 ( CRF 1 ) receptor antagonist with an IC 50 of 66 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW876008. CAS No. 786701-13-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14367. |  |
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1610943-06-0. Pack Sizes: 1 mg. Product ID: HY-P9940. | |
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that binds to both the activated coagulation factor IX and to factor X. Emicizumab has been used in the management and treatment of hemophilia A. Synonyms: Hemlibra. CAS No. 1610943-06-0. | |
| Emidurdar | Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endovion; NS3728. CAS No. 265646-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105917. | |
| Emiglitate | Emiglitate is an α-glucosidase inhibitor that is a powerful inhibitor of glucose-induced insulin release.But no development was reported for the treatment of Diabetes mellitus. Uses: Diabetes mellitus. Synonyms: BAY o 1248; EINECS 279-613-2; Emiglitatum [Latin]; Emiglitate; UNII-PF8AB2IBUM; 1,5-Dideoxy-1,5-((2-(4-(ethoxycarbonyl)phenoxy)ethyl)imino)-D-glucitol. Grade: 98%. CAS No. 80879-63-6. Molecular formula: C17H25NO7. Mole weight: 355.38. | |
| Emiglitate | Emiglitate (BAY o 1248) is a potent, selective and competitive inhibitor of α-glucoside hydrolase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY o 1248. CAS No. 80879-63-6. Pack Sizes: 1 mg. Product ID: HY-16194. | |
| Emimycin | It is produced by the strain of Streptomyces sp. 2020-I. It has anti-gram-positive bacteria, negative bacteria and brewer's yeast and other fungal activities. Synonyms: Enimycin; Pyrazinol, 4-oxide; 2(1H)-Pyrazinone, 4-oxide; 2-Hydroxypyrazine 4-oxide; 1,2-Dihydro-2-oxopyrazine 4-oxide; 4-oxidanidyl-1H-pyrazin-4-ium-2-one. CAS No. 3735-46-4. Molecular formula: C4H4N2O2. Mole weight: 112.09. | |
| Emivirine | Emivirine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(Ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)-2,4(1H,3H)-pyrimidinedione. Appearance: Solid. CAS No. 149950-60-7. Molecular formula: C17H22N2O3. Mole weight: 302.37. IUPACName: 6-benzyl-1-(ethoxymethyl)-5-propan-2-ylpyrimidine-2,4-dione. Canonical SMILES: CCOCN1C(=C(C(=O)NC1=O)C(C)C)CC2=CC=CC=C2. Product ID: ACM149950607. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Emivirine | Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity. Uses: Reverse transcriptase inhibitors. Synonyms: Emivirine; Coactinon; MKC-442; I-EBU; 149950-60-7; 6-BENZYL-1-ETHOXYMETHYL-5-ISOPROPYLURACIL. Grade: 95%. CAS No. 149950-60-7. Molecular formula: C17H22N2O3. Mole weight: 302.372. | |
| Emixustat | Emixustat, a novel visual cycle modulator, is a nonretinoid compound that directly inhibits RPE65, but does not bind to RAR/RXR retinoid receptors or antagonize retinoid binding proteins. Synonyms: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol; ACU-4429; emixustat. CAS No. 1141777-14-1. Molecular formula: C16H25NO2. Mole weight: 263.38. | |
| Emixustat | Emixustat is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429. CAS No. 1141777-14-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720. | |
| Emixustat hydrochloride | Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429 hydrochloride. CAS No. 1141934-97-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720A. | |
| Emixustat hydrochloride | The hydrochloride salt form of Emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Uses: The hydrochloride salt form of emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Synonyms: Emixustat (hydrochloride); UNII-AP4OF2M98B; AP4OF2M98B; EMIXUSTAT HYDROCHLORIDE; 1141934-97-5; Emixustat hydrochloride (USAN). Grade: 98%. CAS No. 1141934-97-5. Molecular formula: C16H26ClNO2. Mole weight: 299.84. | |
| EML-425 | EML-425, a diazinane derivative, has been found to be a CBP/p300 inhibitor that could probably be significant in studies of human leukemia cells. IC50: 1.1 and 2.9 μM, respectively. Synonyms: EML 425; EML-425; EML425; MolPort-042-624-542; BDBM50081125; AKOS027470241; 1,3-dibenzyl-5-[(4-hydroxy-2,6-dimethylphenyl)methylidene]-1,3-diazinane-2,4,6-trione. Grade: 98%. CAS No. 1675821-32-5. Molecular formula: C27H24N2O4. Mole weight: 440.49. | |
| EML4-ALK kinase inhibitor 1 | EML4-ALK kinase inhibitor 1 is a potent and active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. Synonyms: EML4-ALK kinase inhibitor 1; 1373409-08-5; CHEMBL4441960; AKOS040733093; MS-30424; HY-111752; CS-0090752. Grade: 98%. CAS No. 1373409-08-5. Molecular formula: C31H46N8O3. Mole weight: 580.76. | |
| EML741 | EML741 is an inhibitor of histone lysine methyltransferase G9a/GLP, with an IC50 of 23 nM and a Kd of 1.13 μM for G9a. EML741 also inhibits DNMT1 (IC50 = 3.1 μM), with no effect on DNMT3a or DNMT3b. It has low cytotoxicity, cell membrane permeability and blood-brain barrier penetration. Synonyms: 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-7-methoxy-8-(3-(pyrrolidin-1-yl)propoxy)-3H-benzo[e][1,4]diazepin-5-amine; 2-Cyclohexyl-N-(1-isopropyl-4-piperidinyl)-7-methoxy-8-[3-(1-pyrrolidinyl)propoxy]-3H-1,4-benzodiazepin-5-amine; 3H-1,4-Benzodiazepin-5-amine, 2-cyclohexyl-7-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-8-[3-(1-pyrrolidinyl)propoxy]-. CAS No. 2328074-38-8. Molecular formula: C31H49N5O2. Mole weight: 523.75. | |
| Emlenoflast | MCC7840 is a sulfonylurea non-steroidal anti-inflammatory drug and a potent selective inhibitor of NLRP3 inflammasome with IC50 <100 nM. Synonyms: N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-1-(propan-2-yl)-1H-pyrazole-3-sulfonamide; Inzomelid; 1H-Pyrazole-3-sulfonamide, N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-1-(1-methylethyl)-; N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide; MCC7840. CAS No. 1995067-59-8. Molecular formula: C19H24N4O3S. Mole weight: 388.48. | |
| Emlenoflast sodium | Emlenoflast sodium is a sulfonylurea non-steroidal anti-inflammatory drug and a potent selective inhibitor of NLRP3 inflammasome with IC50 <100 nM. Synonyms: MCC7840 sodium. Grade: 98%. CAS No. 2380032-29-9. Molecular formula: C19H23N4NaO3S. Mole weight: 410.47. | |
| Emodepside | Emodepside, also known as PF 1022-221, a semisynthetic derivative of PF1022A, is efficacious against a variety of gastrointestinal nematodes and used as an anthelmintic drug with broad-spectrum anthelmintic activity. Emodepside is an octapeptide drug that has been approved for use in cats. Synonyms: BAY 44-4400; BAY44-4400; BAY-44-4400; BAY 444400; BAY444400; BAY-444400; cyclo[N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)-N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)]; cyclo[N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl-N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl]. Grade: ≥95%. CAS No. 155030-63-0. Molecular formula: C60H90N6O14. Mole weight: 1119.39. | |
| Emodepside | Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay 44-4400. CAS No. 155030-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101476. | |
| Emodin | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics, Stains & Indicators. Formula: C15H10O5. CAS No. 518-82-1. Prepack ID 12987447-100mg. Molecular Weight 270.24. See USA prepack pricing. |  |
| Emodin | Emodin (Frangula emodin), an anthraquinone derivative, is an anti- SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction [1]. Emodin inhibits casein kinase-2 ( CK2 ). Anti-inflammatory and anticancer effects [2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC 50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Frangula emodin. CAS No. 518-82-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-14393. | |
| Emodin | Emodin is an anthraquinone found naturally in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. It has anti-cancer, anti-depressant and anti-microbial effects. Synonyms: Emodol; Frangula emodin; HSDB 7093; NSC 408120; NSC 622947; 3-methyl-1,6,8-trihydroxyanthraquinone; 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Frangulic Acid; Rheum Emodin; Schuttgelb. Grade: 95%. CAS No. 518-82-1. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Emodin | Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,8-trihydroxy-6-methylanthraqunone. Product Category: Inhibitors. Appearance: Powder. CAS No. 518-82-1. Molecular formula: C15H10O5. Mole weight: 270.24. Purity: 0.98. IUPACName: 1,3,8-Trihydroxy-6-methylanthracene-9,10-dione. Canonical SMILES: CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O. Density: 1.33 g/ml. Product ID: ACM518821-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Emodin 1-glucoside | Emodin 1-glucoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 38840-23-2. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Emodin-8-glucoside | Emodin-8-glucoside is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA [1]. Uses: Scientific research. Group: Natural products. CAS No. 23313-21-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0311. | |
| Emodin-8-glucoside (Emodin-8-O- β-D-glucopyranoside) | Emodin-8-glucoside (Emodin-8-O- β-D-glucopyranoside). Group: Biochemicals. Grades: Plant Grade. CAS No. 23313-21-5. Pack Sizes: 10mg. Molecular Formula: C21H20O10, Molecular Weight: 432.38. US Biological Life Sciences. | Worldwide |
| Emodin anthrone | Emodin anthrone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: emodin anthrone;1,3,8-Trihydroxy-6-methyl-10H-anthracen-9-one;1,6,8-Trihydroxy-3-methyl-10-hydroanthracen-9-one;9(10H)-Anthracenone, 1,3,8-trihydroxy-6-methyl-;Aids002046;Aids-002046. Product Category: Heterocyclic Organic Compound. CAS No. 491-60-1. Molecular formula: C15H12O4. Mole weight: 256.25. Product ID: ACM491601. Alfa Chemistry ISO 9001:2015 Certified. | |
| Emodin - CAS 518-82-1 | A cell-permeable, reversible, substrate competitive and potent p56lck tyrosine kinase inhibitor (IC?? = 18.5 μM). Group: Fluorescence/luminescence spectroscopy. |  |
| Emodin-d4 | Labeled Emodin. Occurs mostly as the rhamnoside (see Frangulin) in rhubarb root. Cathartic. Group: Biochemicals. Alternative Names: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione-d4; 1,6,8-Trihydroxy-3-methylanthraquinone-d4; 4,5,7-Trihydroxy-2-methyl-anthraquinone-d4; Archin-d4; Emodin-d4; Emodol-d4; Frangula Emodin-d4; Frangulic Acid-d4; NSC 622947-d4; Rheum Emodin-d4; Schuttgelb-d4. Grades: Highly Purified. CAS No. 132796-52-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Emodin-d4 | Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Emodin-d4;1,3,8-Trihydroxy-6-Methyl-9,10-anthracenedione-d4;1,6,8-Trihydroxy-3-Methylanthraquinone-d4;4,5,7-Trihydroxy-2-Methyl- anthraquinone-d4;Archin-d4;EModol-d4;Frangula EModin-d4;Frangulic Acid-d4. Product Category: Inhibitors. Appearance: Brownish Solid. CAS No. 132796-52-2. Molecular formula: C15H10O5. Mole weight: 270.2369. Purity: 0.96. IUPACName: 1,3,6,8-tetradeuterio-2,4,5-trihydroxy-7-methylanthracene-9,10-dione. Canonical SMILES: O=C1C2=C(O)C([2H])=C(C)C([2H])=C2C(C3=C([2H])C(O)=C([2H])C(O)=C31)=O. Product ID: ACM132796522. Alfa Chemistry ISO 9001:2015 Certified. | |
| Emodin-[d4] | Emodin-[d4] is the labelled analogue of Emodin, which is an anthraquinone found naturally in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. It has anti-cancer, anti-depressant and anti-microbial effects. Uses: Labelled emodin. occurs mostly as the rhamnoside (see frangulin) in rhubarb root. cathartic. Synonyms: Emodin D4; 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione-d4; 1,6,8-Trihydroxy-3-methylanthraquinone-d4; 4,5,7-Trihydroxy-2-methyl-anthraquinone-d4; Archin-d4; Emodin-d4; Emodol-d4; Frangula Emodin-d4; Frangulic Acid-d4; NSC 622947-d4; Rheum Emodin-d4; Schuttgelb-d4. Grade: ≥96%; ≥98% atom D. CAS No. 132796-52-2. Molecular formula: C15H6D4O5. Mole weight: 274.26. | |
| Emodine | Emodine - Product ID: NST-10-73. Category: Anthraquinones. Alternative Names: 4,5,7-Trihydroxy-2-methylanthraquinone. Purity: 98%. Test method: HPLC. CAS No. 518-82-1. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Orange Powder. Molecular formula: C15H10O5. Mole weight: 270.24. Storage: +2 +8 °C. |  |
| emodin O-methyltransferase | The enzyme is involved in biosynthesis of the seco-anthraquinone (+)-geodin. Group: Enzymes. Synonyms: EOMT. Enzyme Commission Number: EC 2.1.1.283. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1890; emodin O-methyltransferase; EC 2.1.1.283; EOMT. Cat No: EXWM-1890. |  |
| Emodin, p56lck Tyrosine Kinase Inhibitor | Occurs mostly as the rhamnoside (see Frangulin) in rhubarb root. Cathartic. Cell-permeable. A naturally occurring anthraquinone that displays a range of biological activities including anti- inflammatory, anti-tumor and neuroprotective effects. Acts as a potent p56lck tyrosine kinase inhibitor (IC50 = 18.5uM). Group: Biochemicals. Alternative Names: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Emodin; Emodol; Frangula Emodin; Frangulic Acid; NSC 408120; NSC 622947; Rheum Emodin; Schuttgelb. Grades: Highly Purified. CAS No. 518-82-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??O?, Molecular Weight: 270.24. US Biological Life Sciences. | Worldwide |
| Emopamil | Emopamil is a calcium channel blocker that can be used to prevent renal injury after warm & cold ischemia. Uses: Calcium channel blockers. Synonyms: Emopamil; 78370-13-5; Emopamil [INN]; Emopamilum [Latin]; Emopamilo [Spanish]. Grade: 95%. CAS No. 78370-13-5. Molecular formula: C23H30N2. Mole weight: 334.504. | |
| Emoxipine | Emoxipine. Group: Biochemicals. Alternative Names: 2-Ethyl-6-methyl-3-pyridinol; 2-Ethyl-3-hydroxy-6-methylpyridine; 2-Ethyl-6-methyl-3-hydroxypyridine. Grades: Highly Purified. CAS No. 2364-75-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H11NO. US Biological Life Sciences. | Worldwide |
| Emoxypine succinate | Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Ethyl-3-hydroxy-6-methylpyridine succinate. CAS No. 127464-43-1. Pack Sizes: 500 mg; 1 g. Product ID: HY-W002620A. | |
| EMPA | EMPA. Group: Biochemicals. Alternative Names: N-Ethyl-2-[ (6-methoxy-3-pyridinyl) [ (2-methylphenyl) sulfonyl]amino]-N- (3-pyridinylmethyl) -acetamide. Grades: Highly Purified. CAS No. 680590-49-2. Pack Sizes: 10mg. Molecular Formula: C23H26N4O4S, Molecular Weight: 454.54. US Biological Life Sciences. | Worldwide |
| EMPA | EMPA is a potent and selective OX2 receptor antagonist (IC50 = 2.3 nM and 1900 nM for OX2 and OX1, respectively) with no activity at a panel of 80 receptors. EMPA blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 = 7.9 nM and 8.8 nM, respectively) and reverses orexin-B-induced hyperlocomotion in mice. Synonyms: N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide. Grade: ≥98% by HPLC. CAS No. 680590-49-2. Molecular formula: C23H26N4O4S. Mole weight: 454.54. | |
| EMPA | EMPA is a high-affinity, reversible and selective orexin OX 2 receptor antagonist. [ 3 H]EMPA binds to human and rat OX 2 -HEK293 membranes with K D values of 1.1 and 1.4 nM respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 680590-49-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108682. | |
| Empagliflozin | Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Synonyms: BI10773; BI-10773; BI 10773; CE0108; CS0940; PB23119; VA10802; AJ93046; Empagliflozin; trade name Jardiance. Grade: >98%. CAS No. 864070-44-0. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin | Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 ( SGLT-2 ) inhibitor with an IC 50 of 3.1 nM for human SGLT-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 10773. CAS No. 864070-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15409. | |
| Empagliflozin | Potent, selective and competitive inhibitor of sodium-glucose cotransporter SGLT2, which is implicated in renal glucose reabsorption. The compound increases urinary glucose excretion, helps decrease hyperglyceamia and maintains glucose homeostasis in diabetic individuals. It has been associated with weight loss, lower blood pressure and decreased glycated haemoglobin. Animal studies suggest that empagliflozin preserves regeneration of β-cells in pancreatic Langerhans islets. Group: Biochemicals. Alternative Names: (1S) -1, 5-Anhydro-1-C- [4-chloro-3- [ [4- [ [ (3S) -tetrahydro-3-furanyl] oxy] phenyl] methyl] phenyl] -D-glucitol. Grades: Highly Purified. CAS No. 864070-44-0. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C23H27ClO7, Molecular Weight: 450.91. US Biological Life Sciences. | Worldwide |
| Empagliflozin 2-O-β-D-glucuronide | Empagliflozin 2-O-β-D-glucuronide is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-2-O-β-D-glucopyranuronosyl-D-glucitol. Molecular formula: C29H35ClO13. Mole weight: 627.03. | |
| Empagliflozin 3-O-β-D-glucuronide | Empagliflozin 3-O-β-D-glucuronide is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol. Molecular formula: C29H35ClO13. Mole weight: 627.03. | |
| Empagliflozin 4-O-β-D-glucuronide | Empagliflozin 4-O-β-D-glucuronide is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-4-O-β-D-glucopyranuronosyl-D-glucitol. Molecular formula: C29H35ClO13. Mole weight: 627.03. | |
| Empagliflozin 6-O-β-D-glucuronide | Empagliflozin 6-O-β-D-glucuronide is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-6-O-β-D-glucopyranuronosyl-D-glucitol. Molecular formula: C29H35ClO13. Mole weight: 627.03. | |
| Empagliflozin α Isomer | Empagliflozin α Isomer is an isomer of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Empagliflozin α-Anomer; (2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1620758-33-9. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin-d4 | Empagliflozin-d 4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BI 10773-d4. CAS No. 2749293-95-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15409S. | |
| Empagliflozin-[d4] | An isotope labelled of Empagliflozin. Empagliflozin is ued for the treatment of type 2 diabetes in adults. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol-d4. Grade: 95% by HPLC; 98% atom D. Molecular formula: C23H23D4ClO7. Mole weight: 454.94. | |
| Empagliflozin Destetrahydrofuran Impurity | An impurity of empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: O-Desethyl Dapagliflozin; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grade: 98%. CAS No. 864070-37-1. Molecular formula: C19H21ClNO6. Mole weight: 380.83. | |
| Empagliflozin Impurity 107 | Empagliflozin Impurity 107. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-tetrahydrofuran-3-yl formate. CAS No. 167979-56-8. Molecular formula: C5H8O3. Mole weight: 116.12. Catalog: APB167979568. | |
| Empagliflozin Impurity 141 | Empagliflozin Impurity 141. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dibromo-5-chlorobenzoic acid. CAS No. 150812-33-2. Molecular formula: C7H3Br2ClO2. Mole weight: 314.36. Catalog: APB150812332. | |
| Empagliflozin Impurity 17 | An impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol; Tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl). CAS No. 2452301-27-6. Molecular formula: C23H28O7. Mole weight: 416.46. | |
| Empagliflozin Impurity 29 | An impurity of Empagliflozin. Empagliflozin is an oral SGLT2 inhibitor used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise. Synonyms: Empagliflozin-D-mannitol Impurity; (2S,3S,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Empagliflozin β-D-mannopyranoside Impurity. Grade: ≥95%. CAS No. 2452301-28-7. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Impurity C | Empagliflozin impurity. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3R)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol; 3'-Epi-Empagliflozin; Empagliflozin (R)-Isomer. Grade: > 95%. CAS No. 864070-43-9. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Methyl Acetate | Empagliflozin Methyl Acetate is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: ((2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl Acetate. CAS No. 2452301-09-4. Molecular formula: C25H29ClO8. Mole weight: 492.95. | |
| Empagliflozin Ortho Isomer | Empagliflozin Ortho Isomer is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grade: ≥98%. CAS No. 2452301-30-1. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Rac Tetrahydrofuran Impurity | An impurity of Empagliflozin. Empagliflozin is an oral SGLT2 inhibitor used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise. Synonyms: Empagliflozin Racemic Mixture; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-((tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[(tetrahydro-3-furanyl)oxy]phenyl]methyl]phenyl]-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[(tetrahydro-3-furanyl)oxy]phenyl]methyl]phenyl]-, (1S)-. Grade: ≥95%. CAS No. 2452301-21-0. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin R-Furanose | Empagliflozin R-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Canagliflozine Furanose Impurity; (2R,3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-31-7. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin R/S-Furanose | An impurity of Empagliflozin. Empagliflozin is an oral SGLT2 inhibitor used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise. Synonyms: Empagliflozin Furanose Recemic; (3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol; (1R)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol and (1S)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Mixture. Grade: ≥95%. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin S-Furanose | Empagliflozin S-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: Jardiance Impurity C; (3R,4R,5R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 1620758-32-8. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Sugar Dimer | A dimer of Empagliflozin. Empagliflozin is an oral SGLT2 inhibitor used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise. Synonyms: (2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-2-(((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Empagliflozin Dimer. Grade: ≥95%. Molecular formula: C46H52Cl2O14. Mole weight: 899.81. | |
| Empagliflozin Sugar Dimer Impurity | An impurity of Empagliflozin. Empagliflozin is an oral SGLT2 inhibitor used to improve glycemic control in adults with type 2 diabetes, often in combination with diet and exercise. Synonyms: 4S-2-Methoxy Empagliflozin Dimer; Empagliflozin sugar dimer; (2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-((((2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol. Grade: ≥95%. CAS No. 2452300-98-8. Molecular formula: C47H54Cl2O15. Mole weight: 929.83. | |
| Empagliflozin Tetraacetoxy | Empagliflozin Tetraacetoxy is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: 1-Methoxy-Empagliflozin Tetraacetoxy; (S)-3-(4-(2-chlorobenzyl)phenoxy)tetrahydrofuran; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-, 2,3,4,6-tetraacetate. Grade: 95%. CAS No. 1620758-21-5. Molecular formula: C32H37ClO12. Mole weight: 649.08. | |
| Empasiprubart | Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2 , preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ARGX-117. CAS No. 2579031-19-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990025. | |
| Empedopeptin | Empedopeptin is produced by the strain of Empedobacter haloabium G393-B445. It has anti-gram-negative bacterial activity. Synonyms: Antibiotic BMY 28117; Antibiotic BU2517. CAS No. 87551-98-2. Molecular formula: C49H79N11O19. Mole weight: 1126.22. | |
| Empesertib | Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC 50 of < 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1161909. CAS No. 1443763-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12858. | |
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