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| Product | Description | |
|---|---|---|
| Epacadostat | Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. Synonyms: IDO inhibitor 1; 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-; [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide; ICBN 24360; ICBN-24360; ICBN24360; INCB 024360; INCB024360; INCB-024360. Grade: ≥95%. CAS No. 1204669-58-8. Molecular formula: C11H13BrFN7O4S. Mole weight: 438.23. |  |
| Epacadostat | Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC 50 of 71.8 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB 024360. CAS No. 1204669-58-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15689. |  |
| Epacmarstobart | Epacmarstobart (FSI-189; GS-0189) is a chimeric humanized IgG1κ antibody targeting the mouse signal regulatory protein SIRPA. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FSI-189; GS-0189. CAS No. 2518200-89-8. Pack Sizes: 1 mg. Product ID: HY-P990019. | |
| Epalrestat | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| Epalrestat | An aldose reductase inhibitor. It is used in treatment of diabetic neuropathy. Group: Biochemicals. Alternative Names: (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grades: Highly Purified. CAS No. 82159-09-9. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Epalrestat | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H13NO3S2. CAS No. 82159-09-9. Prepack ID 65396753-1g. Molecular Weight 319.4. See USA prepack pricing. |  |
| Epalrestat | Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. Uses: Enzyme inhibitors. Synonyms: Kinedak; ONO-2235; ONO 2235; ONO2235; Sorbistat; (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,E)-; 3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; 2-[(Z)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl]acetic acid; Eabeth. Grade: >98%. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat | Epalrestat is an orally available, a non-competitive, reversible inhibitor of aldose reductase (AR), with potential antineoplastic, antioxidant, and anti-inflammatory activities. Alternative Names: Kinedak. Epalrestatum. Epalrestat [INN]. CAS No. 82159-09-9. Product ID: API82159099. Molecular formula: C15H13NO3S2. Mole weight: 319.4. EINECS: 675-018-0. SMILES: C/C(=C\C1=CC=CC=C1)/C=C\2/C(=O)N(C(=S)S2)CC(=O)O. Appearance: Red Solid. Category: Anti-Tumor APIs. |  |
| Epalrestat | Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO2235. CAS No. 82159-09-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-66009. | |
| Epalrestat | Epalrestat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Thiazolidineaceticacid,5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.4. Purity: ≥98%. Product ID: ACM82159099. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Epalrestat-[d5] | One of the isotope labelled form of Epalrestat, which is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (5Z)-5-[(2E)-2-Methyl-3-phenyl-d5-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic Acid; Eabeth-d5; Kinedak-d5; ONO 2235-d5; Sorbistat-d5; Epalrestat-d5; 2-[(Z)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl]acetic acid-d5. Grade: >95%. Molecular formula: C15H8NO3S2D5. Mole weight: 324.43. | |
| Epalrestat Dimer | A dimer impurity of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: Dimer of 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. Grade: >95%. Molecular formula: C30H26N2O6S4. Mole weight: 638.81. | |
| Epalrestat (E,E)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (5E)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5E)-; 2-((E)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grade: >95%. CAS No. 863988-85-6. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (E, Z)-Isomer | Epalrestat (E, Z)-Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((E)-5-((Z)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. CAS No. 124782-64-5. Molecular formula: C15H13NO3S2. Mole weight: 319.40. Catalog: APB124782645. | |
| Epalrestat (E,Z)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (5E)-5-[(2Z)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,Z)-; 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5E)-; (E,Z)-5-(2-Methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid; 2-((E)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grade: >95%. CAS No. 124782-64-5. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat Impurity 24 | Epalrestat Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-5-((E)-2-methyl-3-phenylallylidene)-2-thioxothiazolidin-4-one. CAS No. 15289-56-2. Molecular formula: C13H11NOS2. Mole weight: 261.36. Catalog: APB15289562. | |
| Epalrestat Impurity 25 | Epalrestat Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-methyl-3-phenylacrylaldehyde. CAS No. 15174-47-7. Molecular formula: C10H10O. Mole weight: 146.19. Catalog: APB15174477. | |
| Epalrestat Impurity 29 | Epalrestat Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 15250-29-0. Molecular formula: C10H10O2. Mole weight: 162.19. Catalog: APB15250290. | |
| Epalrestat (Z, Z)-Isomer | Epalrestat (Z, Z)-Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((Z)-5-((Z)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. CAS No. 124782-63-4. Molecular formula: C15H13NO3S2. Mole weight: 319.4. Catalog: APB124782634. | |
| Epalrestat (Z,Z)-Isomer | It is a stereoisomer of Epalrestat, an aldose reductase inhibitor with IC50 of 72 nM. Synonyms: 2-[(5Z)-5-[(2Z)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid; (5Z)-5-[(2Z)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,Z)-; 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grade: >95%. CAS No. 124782-63-4. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epanorin | Epanorin is a lichen metabolite that can inhibit the proliferation of MCF-7 breast cancer cells. Synonyms: L-Leucine, N-[(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)phenylacetyl]-, methyl ester; N-[2-(3-Hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-phenylacetyl]-L-leucine methyl ester; (-)-Epanorin. CAS No. 18463-10-0. Molecular formula: C25H25NO6. Mole weight: 435.47. | |
| EPA OLMO4 Pesticide Standard Mix A | certified reference material, in hexane: toluene (49:1) (varied). Group: Pesticides & metabolites standards. | |
| EpCAM/CD326 human | recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EP Chlorpheniramine Maleate Impurity A (2HCl salt form) | An impurity of Chlorpheniramine. Chlorpheniramine is an antihistamine used to prevent symptoms of allergy. It acts via inhibiting histamine produced during anaphylaxis. Synonyms: 2-(4-Chlorophenyl)-4-(dimethylamino)-2-(2-(dimethylamino)ethyl)butanenitrile; 2-(4-Chlorophenyl)-4-(dimethylamino)-2-[2-(dimethylamino)ethyl]butanenitrile dihydrochloride. Grade: 95%. Molecular formula: C16H26Cl3N3. Mole weight: 366.761. | |
| Epcoritamab | Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20 + tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GEN3013. CAS No. 2134641-34-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99931. | |
| Epcoritamab | Epcoritamab is a bispecific T-cell engager (BiTE) antibody that targets CD3 and CD20. Epcoritamab previously demonstrated potent antitumor activity in dose escalation across B-cell non-Hodgkin lymphoma subtypes. Synonyms: GEN-3013; GEN 3013; GEN3013. Grade: 95%. CAS No. 2134641-34-0. | |
| EPDM | EPDM. Group: Polymers. CAS No. 25038-36-2. |  |
| EPDM chip | EPDM chip. Group: Polymers. | |
| EPDM Rubber | EPDM Rubber. Group: Polymers. | |
| Epelmycin A | It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2alpha,5beta(2S*,6R*),6beta))-tetrahydro-6-methyl-5-((tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-25-0. Molecular formula: C42H53NO15. Mole weight: 811.87. | |
| Epelmycin B | It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 11-Hydroxyauramycin B. CAS No. 107807-24-9. Molecular formula: C42H51NO16. Mole weight: 825.85. | |
| Epelmycin C | It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-23-8. Molecular formula: C36H45NO14. Mole weight: 715.74. | |
| Epelmycin D | It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: Violamycin A4; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-22-7. Molecular formula: C30H35NO11. Mole weight: 585.60. | |
| Epelmycin E | It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 11-Hydroxyaclacinomycin A; 1-Naphthacenecarboxylic acid,1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,12-tetrahydroxy-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; sigma-Rmn-A; epsilon-RMN-A. CAS No. 76264-93-2. Molecular formula: C42H53NO16. Mole weight: 827.87. | |
| Epelsiban | Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation. Uses: Premature ejaculation. Synonyms: GSK-557296; GSK 557296; GSK557296; GSK-557,296-B; (3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione. Grade: 98%. CAS No. 872599-83-2. Molecular formula: C30H38N4O4. Mole weight: 518.65. | |
| Epelsiban besylate | This active molecular, also known as GSK-557296B, is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity over the related vasopressin receptors. Uses: Adenomyosis;infertility; premature ejaculation. Synonyms: GSK557296B; GSK-557296B; (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2-(morpholin-4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione monobenzenesulfonate. Grade: 98%. CAS No. 1159097-48-9. Molecular formula: C36H44N4O7S. Mole weight: 676.83. | |
| Eperezolid | Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). Synonyms: PNU-100592; PNU100592; PNU 100592. Grade: >98%. CAS No. 165800-04-4. Molecular formula: C18H23FN4O5. Mole weight: 394.4. | |
| Eperezolid | Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100592. CAS No. 165800-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10393. | |
| Eperezolid | Eperezolid is a bioavailable synthetic antimicrobial agent with spectra of activity against antibiotic-susceptible and -resistant gram-positive pathogens. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eperezolid; PNU 100592; PNU-100592; PNU100592; U 100592; U-100592; U-100592. Product Category: Others. Appearance: Solid powder. CAS No. 165800-04-4. Molecular formula: C18H20FN4O5. Mole weight: 391.38. Purity: >98%. IUPACName: Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazynyl)phenyl)- 2-oxo-5-oxazolidinyl)methyl)-, (S)-. Canonical SMILES: CC(NC[C@H]1CN(C2=CC=C(C3C#[N]CCN3C(CO)=O)C(F)=C2)C(O1)=O)=O. Product ID: ACM165800044. Alfa Chemistry ISO 9001:2015 Certified. | |
| Eperisone-[d10] Hydrochloride | Eperisone-[d10] Hydrochloride is the labelled analogue of Eperisone HCl. Eperisone relaxes both skeletal muscles and vascular smooth muscles. Synonyms: Eperisone-d10 Hydrochloride; 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl-d10)-1-propanone Hydrochloride; 4'-Ethyl-2-methyl-3-(piperidino-d10)propiophenone Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1246819-46-4. Molecular formula: C17H16D10ClNO. Mole weight: 305.91. | |
| Eperisone-d10 Hydrochloride | Labeled Eperisone. A spasmolytic agent related structurally to Tolperisone. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl-d10)-1-propanone Hydrochloride; 4'-Ethyl-2-methyl-3-(piperidino-d10)propiophenone Hydrochloride; E 0646-d10; EMPP-d10; Mional-d10; Myonal-d10. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Eperisone HCl | Eperisone relaxes both skeletal muscles and vascular smooth muscles. Uses: Anticonvulsants. Synonyms: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride. Grade: > 95%. CAS No. 56839-43-1. Molecular formula: C17H25NO. HCl. Mole weight: 259.39 36.46. | |
| Eperisone hydrochloride | Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. Eperisone Hydrochloride is a potent and selectively P2X7 receptor antagonist, also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascularsmooth muscles, demonstrating a variety of effects such as reduction ofmyotonia, improvement of circulationand and suppression of the pain reflex [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Eperisone hydrochloride. CAS No. 56839-43-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1901. | |
| Eperisone Hydrochloride | A spasmolytic agent related structurally to Tolperisone. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride; 4'-Ethyl -2- methyl -3-piperidinopropiophenon e Hydrochloride; E 0646; EMPP; Mional; Myonal. Grades: Highly Purified. CAS No. 56839-43-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Eperisone impurity 8 | Eperisone impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026-87-5. Molecular formula: C16H24ClNO. Mole weight: 281.82. Catalog: APB1026875. | |
| Epertinib | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R,Z)-1-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178. | |
| Epertinib hydrochloride | Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib HCl; S-222611 hydrochloride; S-222611 HCl. CAS No. 2071195-74-7. Molecular formula: C30H28Cl2FN5O3. Mole weight: 596.48. | |
| Epetirimod | Epetirimod is a small-molecule immune-response modifier intended for the topical treatment of cervical human papilloma virus (HPV) infection and cervical dysplasia. Synonyms: Epetirimod; 227318-71-0; UNII-9P5MH9F521; Epetirimod [USAN:INN]; 851A; S-30563; 9P5MH9F521; 1-(2-Methylpropyl)-1H-imidazo(4,5-c)(1,5)naphthyridin-4-amine; 1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine; 1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine; 851-A; 1H-Imidazo(4,5-c)(1,5)naphthyridin-4-amine, 1-(2-methylpropyl)-; S 30563; Epetirimod [USAN]; EPETIRIMOD [INN]; Epetirimod (INN/USAN); SCHEMBL544542; CHEMBL2103807; DTXSID20177268; UCPMSMNKGXUFCC-UHFFFAOYSA-N; AKOS040751696; TS-08718; D08911; Q27272855. Grade: >98%. CAS No. 227318-71-0. Molecular formula: C23H18F4N6O2S. Mole weight: 518.5. | |
| Epetraborole HCl | This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA; SCHEMBL1980656; CHEMBL3527377; 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol; hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grade: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52. | |
| Epetraborole hydrochloride | Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2251052 hydrochloride. CAS No. 1234563-16-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12479A. | |
| EPHA1 (569-end), active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA1 (569-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA2 (561-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EphA2 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EphA2 antagonist 1 | EphA2 antagonist 1 (4b) is a bile acid conjugate and an ephrin type-A receptor 2 (EPHA2) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1428095-28-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-169849. | |
| EphA2/Fc Chimera from mouse | >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA3 (571-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA4 (610-887), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EphA5/Fc Chimera from rat | >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA6 (561-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EPHA7 (580-end), active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EphA Antagonist (4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic Acid, EphA2 Antagonist, EphA4 Antagoinst, Ephrin Receptor Antagonist, Rtk2 Antagonist, Rtk1 Antagonist) | A pyrrolyl benzoic acid that effectively competes against ephrin-B3 for EphA4 binding as well as against ephrin-A1/-A2/-A3/-A5 for EphA2 and EphA4 binding by targeting EphA2/A4 high affinity ephrin-binding pocket in a reversible manner, exhibiting much reduced or no potency against ephrin-A4 for EphA2/EphA4 binding, ephrin-A5 for EphA3/A5/A6/A7 binding, ephrin-B2 for B1/B2/B3/B4/B6 binding, or ephrin-B2 for EphA4 binding. Shown to inhibit ephrin-A1-induced EphA2 phosphorylation (by 92% at 200uM) and ephrin-A5-induced EphA4 phosphorylation (by 79% at 400uM) in cultures in vitro and prevent ephrin-A5-induced growth cone collapse of neurons in 6-d chicken embryo retina (by 100% at 400uM) ex vivo, as well as rescue human mutant SOD-1 A4V transgene-induced axonopathy in zebrafish embryos (500uM from 6 to 30hpf) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| EPH Aromatic Hydrocarbon Standard | certified reference material, 1000 ?g/mL in methylene chloride. Group: Certified reference materials (crms). | |
| EPHB1 (591-end), active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EphB2 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EphB2/Fc Chimera from mouse | >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| EPHB3 (585-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EPHB4 (561-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| EphB4 active human | recombinant, expressed in baculovirus infected Sf9 cells. Group: Fluorescence/luminescence spectroscopy. | |
| EPH by GC/FID | certified reference material, 50000 ?g/mL in methylene chloride. Group: Certified reference materials (crms). | |
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