A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ent-Galantamine is the (+) enantiomer of Galanthamine and acts as a selective inhibitor of acetylcholinesterase(AChE). Synonyms: Galantamine Impurity F; (4aR,6S,8aR)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol; (+)-Galanthamine. Grades: > 95%. CAS No. 60384-53-4. Molecular formula: C17H21NO3. Mole weight: 287.36.
ent-galanthamine
ent-galanthamine. Group: Biochemicals. Alternative Names: (4aR,6S,8aR)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol; (+)-Galanthamine. Grades: Highly Purified. CAS No. 60384-53-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H21NO3. US Biological Life Sciences.
ent- Galanthamine ((4aR,6S,8aR)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol). Group: Biochemicals. Alternative Names: (4aR,6S,8aR)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Entianin
Entianin is a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity. Molecular formula: C150H247N39O46S5. Mole weight: 3493.12.
ent-Idoxuridine
The enantiomer of Idoxuridine. Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione; 2-Deoxy-L-5-iodouridine; 5-Iodo-2'-deoxy-L-uridine. Grades: Highly Purified. CAS No. 162239-35-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ent-Idoxuridine
The enantiomer of Idoxuridine. Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents. Synonyms: 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione; 2'-Deoxy-L-5-iodouridine; 5-Iodo-2'-deoxy-L-uridine. CAS No. 162239-35-2. Molecular formula: C9H11IN2O5. Mole weight: 354.1.
Entinostat
Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Synonyms: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[ (2-aminophenyl) carbamoyl]phenyl]methyl]carbamate. Grades: > 98%. CAS No. 209783-80-2. Molecular formula: C21H20N4O3. Mole weight: 376.416.
Entinostat
Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies. Group: Biochemicals. Alternative Names: N- [ [4- [ [ (2-Aminophenyl) amino] carbonyl] phenyl] methyl] carbamic Acid 3-Pyridinylmethyl Ester; (Pyridin-3-yl)methyl 4- (2-Aminophenylcarbamoyl) benzylcarbamate; MS 27-275; MS 275; MS 275-27; N-(2-Aminophenyl)-4-[N-(pyridine-3-yl-methoxycarbonyl)-aminomethyl]benzamide; SNDX 275. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Entinostat
Entinostat is an oral and selective class I HDAC inhibitor, with IC 50 s of 243 nM, 453 nM, and 248 nM for HDAC1 , HDAC2 , and HDAC3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MS-275; SNDX-275. CAS No. 209783-80-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12163.
ent-isokaurene C2-hydroxylase
This is the initial step in the conversion of ent-isokaurene to the antibacterial oryzalides in rice, Oryza sativa. Group: Enzymes. Synonyms: CYP71Z6. Enzyme Commission Number: EC 1.14.13.143. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0743; ent-isokaurene C2-hydroxylase; EC 1.14.13.143; CYP71Z6. Cat No: EXWM-0743.
ent-isokaurene synthase
Two enzymes of the rice sub-species Oryza sativa ssp. indica, OsKSL5 and OsKSL6, produce ent-isokaurene. A variant of OsKSL5 from the sub-species Oryza sativa ssp. japonica produces ent-pimara-8(14),15-diene instead [cf. EC 4.2.3.30, ent-pimara-8(14),15-diene synthase]. Group: Enzymes. Synonyms: OsKSL5i; OsKSL6. Enzyme Commission Number: EC 4.2.3.103. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5114; ent-isokaurene synthase; EC 4.2.3.103; OsKSL5i; OsKSL6. Cat No: EXWM-5114.
Ent-Ivabradine Hydrochloride
ent-Ivabradine Hydrochloride is the enantiomer of Ivabradine Hydrochloride; a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7R) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride, (R) -3- [3- [ [ (3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl) methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Monochloride, Bicyclo[4.2.0]octane, 2H-3-benzazepin-2-one deriv. Grades: Highly Purified. CAS No. 167072-91-5. Pack Sizes: 1mg. Molecular Formula: C27H37ClN2O5. US Biological Life Sciences.
Worldwide
ent-kaurene oxidase
Requires cytochrome P-450. Catalyses three sucessive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.78. CAS No. 149565-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0885; ent-kaurene oxidase; EC 1.14.13.78; 149565-67-3. Cat No: EXWM-0885.
ent-kaurene synthase
Part of a bifunctional enzyme involved in the biosynthesis of ent-kaurene. See also EC 5.5.1.13 (ent-copalyl diphosphate synthase). Group: Enzymes. Synonyms: ent-kaurene synthase B; ent-kaurene synthetase B, ent-copalyl-diphosphate diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.2.3.19. CAS No. 9055-64-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5175; ent-kaurene synthase; EC 4.2.3.19; 9055-64-5; ent-kaurene synthase B; ent-kaurene synthetase B, ent-copalyl-diphosphate diphosphate-lyase (cyclizing). Cat No: EXWM-5175.
ent-kaurenoic acid oxidase
Requires cytochrome P-450. Catalyses three sucessive oxidations of ent-kaurenoic acid. The second step includes a ring-B contraction giving the gibbane skeleton. In pumpkin (Cucurbita maxima) ent-6α,7α-dihydroxykaur-16-en-19-oate is also formed. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.79. CAS No. 337507-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0886; ent-kaurenoic acid oxidase; EC 1.14.13.79; 337507-95-6. Cat No: EXWM-0886.
ent-Kaurenol
Ent-Kaurenol is a derivative of ent-Kaurane. Ent-Kaurane is an anti-inflammatory found in plants that inhibits various human neutrophil functions. Synonyms: Kaur-16-en-18-ol; Kaurenol; ent-Kaur-16-en-19-ol; (4α)-Kaur-16-en-18-ol; (-)-Kaur-16-en-18-ol; (-)-Kauren-19-ol. CAS No. 2300-11-0. Molecular formula: C20H32O. Mole weight: 288.47.
ent-Lamivudine
An enantiomer of Lamivudine ; an antiviral that inhibits HIV-reverse transcriptase. Group: Biochemicals. Alternative Names: 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (+)-BCH 189; 2',3'-Dideoxy-3'-thiacytidine; 2'-Deoxy-3'-thiacytidine; 3TC; NSC 620753; cis(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane. Grades: Highly Purified. CAS No. 134680-32-3. Pack Sizes: 1mg. US Biological Life Sciences.
Intermediate in the preparation of Lamivudine derivatives. Group: Biochemicals. Alternative Names: (2S,5R)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1S,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; [1S-[1α(2R*,5S*),2 β,5α]]-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid 5-Methyl-2-(1-methylethyl)cyclohexyl Ester; ent-Lamivudine Acid (1S,2R,5S)-(+)-Menthol Ester; ent-Lamivudine Acid D-Menthol Ester. Grades: Highly Purified. CAS No. 147126-74-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
ent-Lamivudine Triphosphate Triethylammonium Salt
ent-Lamivudine Triphosphate Triethylammonium Salt is a metabolite of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: ((2R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl Tetrahydrogen Triphosphate Triethylammonium Salt. Grades: 96%. Molecular formula: C8H14N3O12P3S.xC6H15N. Mole weight: 469.20 (free acid).
Ent-levobunolol,hydrochloride
Ent-levobunolol,hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (+)-5-[3,(t-Butylamino)-2-hydroxy-propoxy]-3,4-dihydro-1(2H)-naphthalenone, Hydrochloride; d-Bunolol Hydrochloride. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 27867-05-6. Molecular formula: C17H26ClNO3. Mole weight: 327.7. Purity: 0.96. IUPACName: 5-[(2R)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one;hydrochloride. Canonical SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CCCC2=O)O.Cl. ECNumber: 248-725-3. Product ID: ACM27867056. Alfa Chemistry ISO 9001:2015 Certified. Categories: levobunolol hydrochloride.
ent-Levomefolate Calcium
ent-Levomefolate Calcium. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H23CaN7O6, Molecular Weight: 485.51. US Biological Life Sciences.
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ent-Montelukast Sodium Salt
The S-enantiomer of Montelukast. Results indicate that there is no apparent bioinversion of Montelukast to its S-enantiomer in humans. Group: Biochemicals. Alternative Names: 1- [ [ [ (1S) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid Sodium Salt; L 768232. Grades: Highly Purified. CAS No. 190078-45-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ent-Moxifloxacin
The (R,R)-Isomer of Moxifloxacin. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
ent NAP 226-90
ent NAP 226-90. Group: Biochemicals. Alternative Names: 3-[ (1R) -1- (Dimethylamino) ethyl]phenol. Grades: Highly Purified. CAS No. 851086-95-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H15NO. US Biological Life Sciences.
Worldwide
ent-Nateglinide
An impurity found within the commercial pharmaceutical Nateglinide , a novel D-phenylalanine-derivative hypoglycemic agent. Group: Biochemicals. Alternative Names: N-[[trans-4- (1-Methylethyl) cyclohexyl]carbonyl]-L-phenylalanine; L-Nateglinide. Grades: Highly Purified. CAS No. 105816-05-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
ent-Naxagolide Hydrochloride
A dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug. Group: Biochemicals. Alternative Names: (4aS-trans)-3,4,4a,5,6,10b-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol Hydrochloride; (-)-Propyl-9-hydroxynaphthoxazine Hydrochloride;(-)-PHNO. Grades: Highly Purified. CAS No. 100935-99-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Ent-Oseltamivir
Ent-Oseltamivir is an impurity of the antiviral drug oseltamivir, which can be used in COVID19-related research. Synonyms: (3S,4S,5R)-ethyl 4-acetamido; (3S,4S,5R)-ethyl 4-acetamido-5-amino. CAS No. 1035895-88-5. Molecular formula: C16H28N2O4. Mole weight: 312.40.
ent-oseltamivir phosphate
ent-oseltamivir phosphate. Group: Biochemicals. Alternative Names: (3S,4S,5R)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate. Grades: Highly Purified. CAS No. 1035895-89-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H31N2O8P. US Biological Life Sciences.
Worldwide
ent-Oseltamivir Phosphate
ent-Oseltamivir Phosphate is the enatiomer of Oseltamivir Phosphate, which is a prodrug of the influenza neuraminidase inhibitor Oseltamivir. Synonyms: (3S,4S,5R)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate; 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3S,4S,5R)-, phosphate (1:1); (3S,4S,5R)-Ethyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate phosphate. Grades: ≥95%. CAS No. 1035895-89-6. Molecular formula: C16H31N2O8P. Mole weight: 410.40.
Entospletinib
Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM. Phase 2. Synonyms: GS9973; GS 9973; GS-9973. Grades: >98%. CAS No. 1229208-44-9. Molecular formula: C23H21N7O. Mole weight: 411.46.
Entospletinib
Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with an IC 50 of 7.7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9973. CAS No. 1229208-44-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15968.
ent-Paroxetine Hydrochloride
An enantiomeric impurity of Paroxetine. Group: Biochemicals. Alternative Names: (3R-trans) -3-[ (1, 3-Benzodioxol-5-yloxy) methyl]-4- (4-fluorophenyl) piperidine Hydrochloride; (3R, 4S) -3-[ (1, 3-Benzodioxol-5-yloxy) methyl]-4- (4-fluorophenyl) piperidine Hydrochloride. Grades: Highly Purified. CAS No. 130855-30-0. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
ent-Paroxetine Hydrochloride
An impurity of Paroxetine which is an oral antidepressant formally approved in the United States. Synonyms: (3R-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride; (3R,4S)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride; USP Paroxetine Related Compound C; Paroxetine EP Impurity D. Grades: > 95%. CAS No. 130855-30-0. Molecular formula: C19H20FNO3.HCl. Mole weight: 365.83.
ent-Paroxol
Paroxol can be used to synthesis Paroxetine. Synonyms: (3R,4S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol; (+)-Paroxol; (+)-trans-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine; (3R,4S)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine. Grades: > 95%. CAS No. 389573-45-9. Molecular formula: C13H18FNO. Mole weight: 223.29.
ent-Paroxol
An intermediate in the synthesis of Paroxetine , a selective serotonin reuptake inhibitor. Group: Biochemicals. Alternative Names: (3R,4S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol; (+)-Paroxol. Grades: Highly Purified. CAS No. 389573-45-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
ent-pazufloxacin mesylate
ent-pazufloxacin mesylate. Group: Biochemicals. Alternative Names: (3R)-10-(1-Aminocyclopropyl)-9-fluror-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid methanesulfonate; (R)-Pazufloxacin. Grades: Highly Purified. CAS No. 677004-96-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H19FN2O7S. US Biological Life Sciences.
Worldwide
Ent-pazufloxacin mesylate
Ent-pazufloxacin mesylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3R)-10-(1-Aminocyclopropyl)-9-fluror-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Methanesulfonate; (R)-Pazufloxacin. Product Category: Heterocyclic Organic Compound. CAS No. 677004-96-5. Molecular formula: C17H19FN2O7S. Mole weight: 414.41. Purity: 0.96. IUPACName: ent-Pazufloxacin Mesylate. Canonical SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O. Product ID: ACM677004965. Alfa Chemistry ISO 9001:2015 Certified.
ent-pimara-8(14),15-diene synthase
Unlike EC 4.2.3.29, ent-sandaracopimaradiene synthase, which can produce both ent-sandaracopimaradiene and ent-pimara-8(14),15-diene, this diterpene cyclase produces only ent-pimara-8(14),15-diene. ent-Pimara-8(14),15-diene is not a precursor in the biosynthesis of either gibberellins or phytoalexins. Group: Enzymes. Synonyms: OsKS5. Enzyme Commission Number: EC 4.2.3.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5188; ent-pimara-8(14),15-diene synthase; EC 4.2.3.30; OsKS5. Cat No: EXWM-5188.
ent-pimara-9(11),15-diene synthase
This enzyme is involved in the biosynthesis of the diterpenoid viguiepinol and requires Mg2+, Co2+, Zn2+ or Ni2+ for activity. Group: Enzymes. Synonyms: PMD synthase. Enzyme Commission Number: EC 4.2.3.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5189; ent-pimara-9(11),15-diene synthase; EC 4.2.3.31; PMD synthase. Cat No: EXWM-5189.
Entrectinib
Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Phase 2. Uses: Protein kinase inhibitors. Synonyms: RXDX101; RXDX 101; RXDX-101; NMS E628; NMS-E628; Entrectinib; N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide. Grades: ≥98%. CAS No. 1108743-60-7. Molecular formula: C31H34F2N6O2. Mole weight: 560.64.
Entrectinib
Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. RXDX-101 has demonstrated potent pharmacological activity in preclinical studies and has the potential to be first-in-class against the Trk family of kinases. PXDX-101 has been well tolerated in patients with advanced solid tumors. PXDX-101 is currently in clinical trials, and is being developed by Ignyta. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RXDX101; RXDX 101; RXDX-101; NMS E628; NMSE628; NMS-E628; Entrectinib. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1108743-60-7. Molecular formula: C31H34F2N6O2. Mole weight: 560.64. Purity: >98%. IUPACName: N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide. Canonical SMILES: O=C(NC1=NNC2=C1C=C(CC3=CC(F)=CC(F)=C3)C=C2)C4=CC=C(N5CCN(C)CC5)C=C4NC6CCOCC6. Product ID: ACM1108743607. Alfa Chemistry ISO 9001:2015 Certified.
Entrectinib
Entrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C , ROS1 and ALK , with IC 50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NMS-E628; RXDX-101. CAS No. 1108743-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12678.
An enantiomer of Rosuvastatin. Group: Biochemicals. Alternative Names: (3S, 5R, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid Sodium Salt; (3S,5R)-Rosuvastatin Sodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
ent-rosuvastatin tert-butyl ester
ent-rosuvastatin tert-butyl ester. Group: Biochemicals. Alternative Names: (3S, 5R, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid tert-Butyl Ester. Grades: Highly Purified. CAS No. 615263-60-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C26H36FN3O6S. US Biological Life Sciences.
Worldwide
ent-Rosuvastatin tert-Butyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3S,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester. Grades: > 95%. CAS No. 615263-60-0. Molecular formula: C26H36FN3O6S. Mole weight: 537.66.
ent-Rotigotine
ent-Rotigotine is a non-ergot dopamine agonist drug used to treat Parkinson's disease. Synonyms: 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6R)-; (6R)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol; 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (R)-; (+)-N 0437; N 0924; (R)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol; (+)-Rotigotine; (R)-Rotigotine. Grades: ≥95%. CAS No. 112835-48-0. Molecular formula: C19H25NOS. Mole weight: 315.47.
ent-sandaracopimaradiene 3-hydroxylase
A heme-thiolate protein (cytochrome P-450). Isolated from Oryza sativa (rice). Participates in the pathway for the biosynthesis of oryzalexins, a group of related phytoalexins produced by rice. Group: Enzymes. Synonyms: CYP701A; OsKOL4. Enzyme Commission Number: EC 1.14.13.191. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0791; ent-sandaracopimaradiene 3-hydroxylase; EC 1.14.13.191; CYP701A; OsKOL4. Cat No: EXWM-0791.
ent-sandaracopimaradiene synthase
ent-Sandaracopimaradiene is a precursor of the rice oryzalexins A-F.Phytoalexins are diterpenoid secondary metabolites that are involved in the defense mechanism of the plant, and are produced in response to pathogen attack through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation. As a minor product, this enzyme also forms ent-pimara-8(14),15-diene, which is the sole product ofEC 4.2.3.30, ent-pimara-8(14),15-diene synthase. ent-Pimara-8(14),15-diene is not a precursor in the biosynthesis of either gibberellins or phytoalexins. Group: Enzymes. Synonyms: OsKS10; ent-sandaracopimara-8(14),15-diene synthase. Enzyme Commission Number: EC 4.2.3.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5186; ent-sandaracopimaradiene synthase; EC 4.2.3.29; OsKS10; ent-sandaracopimara-8(14),15-diene synthase. Cat No: EXWM-5186.
ent S-(+)-atomoxetine hydrochloride
ent S-(+)-atomoxetine hydrochloride. Group: Biochemicals. Alternative Names: (gamma-S) -N-Methyl-gamma- (2-methylphenoxy) benzenepropanamine hydrochloride; (S)-(+)-Tomoxetine hydrochloride; (S)-Tomoxetine hydrochloride. Grades: Highly Purified. CAS No. 82857-39-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H22ClNO. US Biological Life Sciences.
Worldwide
Ent s-(+)-atomoxetine hydrochloride
Ent s-(+)-atomoxetine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (γS)-N-Methyl-γ-(2-methylphenoxy)benzenepropanamine Hydrochloride; (S)-(+)-Tomoxetine Hydrochloride; (S)-Tomoxetine Hydrochloride; LY 139602. Product Category: Heterocyclic Organic Compound. CAS No. 82857-39-4. Molecular formula: C17H22ClNO. Mole weight: 291.82. Purity: 0.96. IUPACName: (3S)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;hydrochloride. Canonical SMILES: CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2.Cl. Product ID: ACM82857394. Alfa Chemistry ISO 9001:2015 Certified.
ent-Sofosbuvir Desphosphate
ent-Sofosbuvir Desphosphate is a possible metabolite of prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
ent-Tadalafil
Tadalafil analog. Group: Biochemicals. Alternative Names: (6S, 12aS)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 6, 7, 12, 12a-hexahydro-2-methyl-pyrazino[1', 2':1, 6]pyrido[3, 4-b]indole-1, 4-dione; L-Tadalafil; L-Tildenafil. Grades: Highly Purified. CAS No. 629652-72-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
ent-Tadalafil-d3
Tadalafil analog. Group: Biochemicals. Alternative Names: (6S, 12aS)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 6, 7, 12, 12a-hexahydro-2-(methyl-d3)-pyrazino[1', 2':1, 6]pyrido[3, 4-b]indole-1, 4-dione; L-Tadalafil-d3; L-Tildenafil-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
ent-Thiamphenicol-d3
The labeled enatiomeric analogue of the antimicrobial agent Thiamphenicol. Group: Biochemicals. Alternative Names: 2, 2-Dichloro-N-[ (1S, 2S) -2-hydroxy-1- (hydroxymethyl) -2-[4- (methylsulfonyl) phenyl]ethyl]acetamide-d3; L-threo-2,2-Dichloro-N-[ β -hydroxy-α - (hydroxymethyl) -p- (methylsulfonyl) phenethyl]Acetamide-d3; Thiamphenicol Epimer-d3; Win 5063-3-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
ent-Valsartan
ent-Valsartan is the (R)-enantiomer of Valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 137862-87-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ent-Voriconazole
The (2S,3R) enantiomer in Voriconazole drug substance. Group: Biochemicals. Alternative Names: (αS, βR)-α-(2,4-Difluorophenyl)-5-fluoro- β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; [S-(R*,S*)]-. Grades: Highly Purified. CAS No. 137234-63-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ent-Voriconazole
ent-Voriconazole. Uses: For analytical and research use. Group: Impurity standards. CAS No. 137234-63-0. Pack Sizes: 5MG. IUPAC Name: (2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol. Molecular Formula: C16H14F3N5O. Mole Weight: 349.31. Catalog: APS137234630. SMILES: C[C@H] (c1ncncc1F)[C@@] (O) (Cn2cncn2)c3ccc (F)cc3F. Format: Neat. Shipping: Room Temperature.
Envafolimab
Envafolimab (ASC 22; KN 035) is a recombinant protein of a humanized single-domain anti- PD-L1 antibody. Envafolimab is created by a fusion of the of anti-PD-L1 domain with Fc fragment of human IgG1 antibody. Envafolimab blocks interaction between PD-L1 and PD-1 with an IC 50 value of 5.25 nM. Envafolimab has the potential for the research of solid tumors [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASC 22; KN 035. CAS No. 2102192-68-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99115.
Envafolimab
Envafolimab is a recombinant protein of a humanized single-domain anti-PD-L1 antibody. Envafolimab has obtained the U.S. FDA's orphan drug designation for advanced biliary tract cancer. Synonyms: ASC 22; ASC22; ASC-22; KN 035; KN035; KN-035. CAS No. 2102192-68-5.
envelysin
A glycoprotein from various members of the class Echinoidea. Extracellular enzyme requiring Ca2+. In peptidase family M10 (interstitial collagenase family). Group: Enzymes. Synonyms: sea-urchin-hatching proteinase; hatching enzyme; chorionase; chorion-digesting proteinase; chymostrypsin; sea urchin embryo hatching enzyme. Enzyme Commission Number: EC 3.4.24.12. CAS No. 50812-13-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4293; envelysin; EC 3.4.24.12; 50812-13-0; sea-urchin-hatching proteinase; hatching enzyme; chorionase; chorion-digesting proteinase; chymostrypsin; sea urchin embryo hatching enzyme. Cat No: EXWM-4293.
Enviomycin
Enviomycin (Tuberactinomycin N) is a antibacterial antibiotic. Enviomycin has been used to research chronic cavitary pulmonary tuberculosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Enviomycin;1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv.;enviomucin;Tuberactinomycin N (8CI, 9CI);Viomycin, 1-[(3R,4R)-4-hydroxy-3,6-diaminohexanoic acid]-6-[L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)glycine]-, (R)-;N2-[(4R)-4-Hydroxy-L-. Product Category: Inhibitors. CAS No. 33103-22-9. Molecular formula: C25H43N13O10. Mole weight: 685.696. Purity: 0.96. IUPACName: 3,6-diamino-N-[(6Z)-3-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]-4-hydroxyhexanamide. Density: 1.8g/cm³. Product ID: ACM33103229. Alfa Chemistry ISO 9001:2015 Certified.
Environox Dark Brown
A manufactured pigment Excellent UV Stability Suitable for all mediums Not Cosmetic or Pharmaceutical Grade Lime and Cement Color Stable. Uses: Designed for use in research and industrial production. Product Category: Pigments. CAS No. 1317-63-1. Molecular formula: Fe203. Product ID: ACM1317631-1. Alfa Chemistry ISO 9001:2015 Certified.
Enviroxime
Enviroxime is a benzimidazole derivative that inhibits the replication of rhinoviruses and poliovirus by targeting protein 3A. Enviroxime exhibits antiviral effects against EV71 with EC50 of 0.15 μM. Uses: Coxsackievirus infections; picornavirus infections. Synonyms: (1E)-[2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone Oxime; 6-[(E)-(Hydroxyimino)phenylmethyl]-1-[(1-methylethyl)sulfonyl]- 1H-Benzimidazol-2-amine; LY 122772; LY122772; LY-122772. Grades: 98%. CAS No. 72301-79-2. Molecular formula: C17H18N4O3S. Mole weight: 358.41.
Enythromycin
Erythromycin (EM,Er) is produced from streptomycin and is an alkaline antibiotic. These include erythromycin A(ErA)Chemicalbook, erythromycin B(ErB), erythromycin C(ErC), erythromycin D(ErD), erythromycin E(ErE), and erythromycin F(ErF). Synonyms: StreptoMyces erythreus;knin;(-)-ErythroMycin, Eur.Ph.;ErythroMycin COS/CGMP;ERYTHROMYCIN THICYANATE;Ilotycin, ErythroMycin;abboticin;abomacetin. CAS No. 114-07-8. Product ID: PAP-0054. Molecular formula: C37H67NO13. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Enythromycin; PAP-0054; Anti-Infectives; C37H67NO13; 114-07-8. Chemical Name: (-)-ErythroMycin. Grade: Pharmaceutical Grade. Product Description: (-)-ErythroMycin.
Enzalutamide
Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM. It inhibits the activity of prostate cancer cell Ars, which over expressed in prostate cancer. Uses: Potential antineoplastic agent. Synonyms: MDV3100; MDV 3100; MDV-3100; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; S-Enzalutamide; Xtandi. Grades: >98%. CAS No. 915087-33-1. Molecular formula: C21H16F4N4O2S. Mole weight: 464.44.
Enzalutamide
Enzalutamide. CAS No. 915087-33-1. Product ID: 8-05080. Molecular formula: C22H16F4O2S. Mole weight: 464.44. Properties: androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells; increases autophagy.
Enzalutamide
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC 50 of 36 nM in LNCaP prostate cells. Enzalutamide is an autophagy activator [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDV3100. CAS No. 915087-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-70002.
Enzalutamide Carboxylic Acid
Enzalutamide Carboxylic Acid is a metabolite of Enzalutamide. Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer. Synonyms: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-benzoic Acid. CAS No. 1242137-15-0. Molecular formula: C20H13F4N3O3S. Mole weight: 451.4.
Enzalutamide Impurity 1
Enzalutamide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzoic acid. CAS No. 1242137-15-0. Molecular Formula: C20H13F4N3O3S. Mole Weight: 451.39. Catalog: APB1242137150.