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| Product | Description | |
|---|---|---|
| Jervine | Jervine. Group: Biochemicals. Grades: Purified. CAS No. 469-59-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Jervine ((3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one) | Has antibacterial properties. Jervine demonstrates teratogenic properties. It is the starting material for C-nor-D-homosteroids. Jervine induces holoprosencephaly and blocks endogenous Sonic hedgehog signaling. Group: Biochemicals. Alternative Names: (3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Jesaconitine | Jesaconitine. Group: Biochemicals. Grades: Highly Purified. CAS No. 16298-90-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C35H49NO12. US Biological Life Sciences. | Worldwide |
| JET-209 | JET-209 is a potent PROTAC CBP/p300 degrader, with DC50 values of 0.05 nM and 0.2 nM for CBP and p300. JET-209 contains Lenalidomide (HY-A0003) (the cereblon ligand), a linker and GNE-207 (HY-120028) (bromodomain Inhibitor). JET-209 is used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033714-58-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-154984. |  |
| JF5 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Jfd00244 | JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 96969-83-4. Molecular formula: C30H26N2O4. Mole weight: 478.54. Purity: 0.9803. Canonical SMILES: O=C1C2=C(C=CC=C2)C(C3=C(NCCC4=CC=C(O)C=C4)C=CC(NCCC5=CC=C(O)C=C5)=C13)=O. Product ID: ACM96969834. Alfa Chemistry ISO 9001:2015 Certified. |  |
| JFD01307SC | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JG-2016 | JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1) with an IC50 of 14.8 ?M. JG-2016 can inhibit the growth of multiple tumor cells and has anti-tumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2887480-87-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154944. | |
| JG26 | JG26 is an ADAM17 inhibitor, with IC 50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM for ADAM8, ADAM17, ADAM10 and MMP-12, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1464910-32-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120852. | |
| JG-98 | JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1456551-16-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117282. | |
| JH-RE-06 | JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 ?M; Kd=0.42 ?M), targets REV1 that interacts with the REV7 subunit of POL?. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POL?. JH-RE-06 improves chemotherapy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361227-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126214. | |
| JHU-083 | JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1998725-11-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122218. | |
| JHU395 | JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2079938-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128775. | |
| JHW 007 hydrochloride | JHW 007 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 202645-74-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JH-X-119-01 | Jh-X-119-01 is a novel potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 irreversibly labels IRAK1 at C302. This compound exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88. Cotreatment of JH-X-119-01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JH-X-119-01; JH-X119-01; JH-X 119-01; JH-X-11901; JH-X11901; JH-X 11901; JHX-11901; JHX11901; JHX 11901. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2227368-54-7. Molecular formula: C25H20N6O3. Mole weight: 452.47. Purity: >98%. IUPACName: N-(4-(3-Acrylamidobenzamido)phenyl)-6-(1H-pyrazol-5-yl)picolinamide. Canonical SMILES: O=C(NC1=CC=C(NC(C2=CC=CC(NC(C=C)=O)=C2)=O)C=C1)C3=NC(C4=CC=NN4)=CC=C3. Product ID: ACM2227368547. Alfa Chemistry ISO 9001:2015 Certified. | |
| JH-X-119-01 | JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice [1]. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC 50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2227368-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103017A. | |
| JH-X-119-01 hydrochloride | JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2591344-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-103017. | |
| JI-101 | JI-101 is an orally available multi-kinase inhibitor of VEGFR2, PDGFR? and EphB4 with potent anti-cancer activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 900573-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16265. | |
| JIB 04 | JIB 04. Group: Biochemicals. Grades: Purified. CAS No. 199596-05-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JIB-04 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JIB-04 | JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC 50 s of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 199596-05-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13953. | |
| JIB-04 | JIB-04 Inhibitor. Uses: Scientific use. Product Category: T1868. CAS No. 199596-05-9. |  |
| Jietacin A | Jietacin A is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. Synonyms: Jietacine A; BRN 5538455; 1-(Ethenyl-ONN-azoxy)-14-methyl-8-pentadecanone. CAS No. 109766-61-2. Molecular formula: C18H34N2O2. Mole weight: 310.47. |  |
| Jietacin B | Jietacin B is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. CAS No. 109766-62-3. Molecular formula: C19H36N2O2. Mole weight: 324.50. | |
| Jindongenin-1a | Jindongenin-1a is an antibacterial peptide isolated from Amolops jingdongensis (Chinese torrent frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Jindongenin-1a can help to solve the serious problem of bacterial resistance to currently used antibiotics. Synonyms: Ser-Met-Gly-Ala-Val-Lys-Leu-Ala-Lys-Leu-Leu-Ile-Asp-Lys-Met-Lys-Cys-Glu-Val-Thr-Lys-Ala-Cys. Grade: 95.6%. | |
| Jinflexin A | Jinflexin A is a remarkable and potent pharmacological natural compound, finding extensive application for studying various ailments such as rheumatoid arthritis, osteoarthritis and diverse inflammatory joint disorders. This multifaceted natural compound exerts its mechanism of action via the proficient inhibition of pro-inflammatory cytokine production. Grade: 96.0%. CAS No. 2055155-75-2. Molecular formula: C19H22O3. Mole weight: 298.382. | |
| Jingdongin-1 | Jingdongin-1 is an antibacterial peptide isolated from Amolops jingdongensis (Chinese torrent frog). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Phe-Leu-Pro-Leu-Phe-Leu-Pro-Lys-Ile-Ile-Cys-Val-Ile-Thr-Lys-Lys-Cys. Grade: 96.4%. Mole weight: 1976.6. | |
| Jingzhaotoxin III | Jingzhaotoxin III. Group: Biochemicals. Grades: Purified. CAS No. 925463-91-8. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Jingzhaotoxin III | Jingzhaotoxin III is a selective blocker of NaV1.5 channels with IC50 value of 348 nM. It is selective for NaV1.5 channels and shows no effect on other isoforms. It inhibits the activation of cardiac sodium channels by binding to the NaV1.5 S3-S4 linker of domain II. It has no effect on sodium channels in dorsal root ganglion neurons. Synonyms: H-Asp-Gly-Glu-Cys(1)-Gly-Gly-Phe-Trp-Trp-Lys-Cys(2)-Gly-Arg-Gly-Lys-Pro-Pro-Cys(3)-Cys(1)-Lys-Gly-Tyr-Ala-Cys(2)-Ser-Lys-Thr-Trp-Gly-Trp-Cys(3)-Ala-Val-Glu-Ala-Pro-OH; L-alpha-aspartyl-glycyl-L-alpha-glutamyl-L-cysteinyl-glycyl-glycyl-L-phenylalanyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-glycyl-L-arginyl-glycyl-L-lysyl-L-prolyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-lysyl-glycyl-L-tyrosyl-L-alanyl-L-cysteinyl-L-seryl-L-lysyl-L-threonyl-L-tryptophyl-glycyl-L-tryptophyl-L-cysteinyl-L-alanyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-proline (4->19),(11->24),(18->31)-tris(disulfide). Grade: >98%. CAS No. 925463-91-8. Molecular formula: C174H241N47O46S6. Mole weight: 3918.44. | |
| Jionoside A1 | Jionoside A1. Group: Biochemicals. CAS No. 120444-60-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Jionoside B1 | Jionoside B1. Group: Biochemicals. Grades: Plant Grade. CAS No. 120406-37-3. Pack Sizes: 5mg. Molecular Formula: C37H50O20, Molecular Weight: 814.79. US Biological Life Sciences. | Worldwide |
| JIP-1 (153-163) | JIP-1 (153-163) has been found to be a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Synonyms: TI-JIP. Grade: >98%. CAS No. 438567-88-5. Molecular formula: C61H104N20O14. Mole weight: 1341.6. | |
| JIP-1 (153-163) acetate | JIP-1 (153-163) acetate is a c-Jun N-terminal kinase (JNK) peptide inhibitor based on JNK-interacting protein-1 (JIP-1) residues 153-163. It binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK. Synonyms: L-Phenylalaninamide, L-arginyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-threonyl-L-threonyl-L-leucyl-L-asparaginyl-L-leucyl-, acetate (1:1); H-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH2.CH3CO2H; L-arginyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-threonyl-L-threonyl-L-leucyl-L-asparagyl-L-leucyl-L-phenylalaninamide acetate salt. Grade: ≥95%. CAS No. 1417623-78-9. Molecular formula: C61H104N20O14.C2H4O2. Mole weight: 1401.66. | |
| JJKK 048 | JJKK 048 is a highly selective and potent monoacylglycerol lipase (MAGL) inhibitor with IC 50 values of 214 pM, 275 pM and 363 pM for human, rat, and mouse MAGL. JJKK 048 displays low cross-reactivity with other endocannabinoid targets. JJKK 048 can be used in the research of diseases such as cancer, neurodegenerative diseases, and pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1515855-97-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108613. | |
| JJKK 048 | JJKK 048. Group: Biochemicals. Grades: Purified. CAS No. 1515855-97-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| JJKK-048 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JK184 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| JK 184 | JK 184. Group: Biochemicals. Grades: Purified. CAS No. 315703-52-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JK 184 (N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine) | An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC50 = 210 nM). Group: Biochemicals. Alternative Names: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine. Grades: Highly Purified. CAS No. 315703-52-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| JK-2 | ?90% (NMR). Group: Fluorescence/luminescence spectroscopy. | |
| JKC 363 | JKC 363. Group: Biochemicals. Grades: Purified. CAS No. 436083-30-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| JKC 363 | JKC 363 has been found to be a melanocortin MC4 receptor antagonist and could suppress the release of thyrotropin-releasing hormone (TRH). Synonyms: (Deamino-Cys11,D-2-Nal14,Cys18)-β-MSH (11-22) amide; JKC363; JKC-363; 3-Mercaptopropionyl-Glu-His-D-2-Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (Disulfide bond); deamino-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asn-OH (Disulfide bridge: Cys1-Cys8); deamino-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-asparagine (1->8)-disulfide; beta-MSH (11-12)-amide, mercaptopropionic acid(11)-naphthylalanyl(14)-cysteinyl(18)-aspartyl(22)-; beta-MSH (11-22)-amide, Mrp(11)-Nal(14)-Cys(18)-Asp(22)-; [Deamino-Cys11,β-(2-Naphthyl)-D-Ala14,Cys18]-β-Melanocyte Stimulating Hormone Amide Fragment 11-22. Grade: ≥95% by HPLC. CAS No. 436083-30-6. Molecular formula: C69H91N19O16S2. Mole weight: 1506.72. | |
| JKE-1674 | JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and an active metabolite of GPX4 inhibitor ML-210. JKE-1674, an analog of ML-210 in which the nitroisoxazole ring is replaced with an ?-nitroketoxime. JKE-1674 can convert into a nitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in a manner that is equipotent to ML-210 and is completely rescued by ferroptosis inhibitors[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2421119-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138153. | |
| JK-P3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JLK 6 | JLK 6. Group: Biochemicals. Grades: Purified. CAS No. 62252-26-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JM6 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD1A human | recombinant, expressed in baculovirus infected Sf9 cells, ?40% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD1C-IN-1 | JMJD1C-IN-1 (compound 193D7) is an inhibitor of JMJD1C with oral activity. JMJD1C-IN-1 targets tumor Treg cells without affecting systemic immune homeostasis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 861224-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162275. | |
| JMJD2A Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD2C Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD2D active human | recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD3/KDM6B Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD6 human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| JMJD Histone Demethylase Inhibitor III ( (E) -4- (Hydroxy (4- (4- ( (naphthalen-1-ylcarbamoyloxy) methyl) benzylamino) butyl) amino) -4-oxobut-2-enoic Acid) | A substrate (methyl lysine) and cofactor (a-ketoglutarate) mimicking bivalent benzylamino-butylamino-N-hydroxybutenoic acid compound that acts as a selective in vitro inhibitor of Jumonji domain-containing histone demethylases (JHDMs; IC50=4.3, 3.4, 5.9, 10 and 43uM for JMJD2A, JMJD2C, JMJD2E, PHF8 and JMJD3, respectively) over LSD1, asparaginyl and prolyl hydroxylases, and histone deacetylases (IC50=54, 83, 31, 22, 620, 680 and >800uM for PHD1, PHD2, PHD3, FIH, LSD1 and HDACs, respectively). The cellular active JHDM Inhibitor, Methylstat is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| JMJD Histone Demethylase Inhibitor IV, Methylstat ( (E) -Methyl-4- (hydroxy (4- ( (4- ( ( (naphthalen-1-ylcarbamoyl) oxy) methyl) benzyl) amino) butyl) amino) -4-oxobut-2-enoate, Histone Lysine Demethylase Inhibitor VII, Methylstat) | A methyl ester prodrug of in vitro active N-hydroxybutenoic acid compound that is shown to preferentially induce hypermethylation of histone proteins (EC50 for H3K4me3 and H3K9me3=10.3 and 8.6uM in KYSE150 cells, and 6.7 and 6.3uM in MCF7 cells, respectively), and arrests cell growth. Acts as a selective inhibitor of Jumonji domain-containing histone demethylases (JHDMs) over prolyl hydroxylases (PHDs), and prevents myogenesis through inhibition of H3K27 demethylase UTX in C2C12 cells at 2uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| JMS-17-2 | JMS-17-2 is a potent and selective antagonist of CX3CR1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JMS-17-2; JMS172; JMS 17 2; JMS17-2; JMS-172; JMS 17-2; JMS-17 2. Product Category: Antagonists. Appearance: Solid powder. CAS No. 1380392-05-1. Molecular formula: C25H26ClN3O. Mole weight: 419.95. Purity: >98%. IUPACName: 5-(3-(4-(4-Chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one. Canonical SMILES: O=C1C2=CC=CN2C3=C(C=CC=C3)N1CCCN4CCC(C5=CC=C(Cl)C=C5)CC4. Product ID: ACM1380392051. Alfa Chemistry ISO 9001:2015 Certified. Categories: J-M172. | |
| JMS-17-2 | JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC 50 of 0.32 nM. JMS-17-2 impairs metastatic seeding and colonization of breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380392-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-123918. | |
| JMV 390-1 | JMV 390-1 has been found to be an inhibitor of the major neurotensin and neuromedin N degrading enzymes and could probably show analgesic activities. Synonyms: Jmv-390-1; Jmv390-1; N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine. Grade: ≥95% by HPLC. CAS No. 148473-36-3. Molecular formula: C23H35N3O6. Mole weight: 449.54. | |
| JMV 390-1 | JMV 390-1. Group: Biochemicals. Grades: Purified. CAS No. 148473-36-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| JMV 449 | JMV 449. Group: Biochemicals. Grades: Purified. CAS No. 139026-66-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| JMV 449 | JMV 449 could be a neurotensin receptor agonist peptide and has been found to show hypothermic and analgesic activities in the mouse. Synonyms: JMV-449; JMV449; (S)-1-de-L-lysine-2-[N2-(2,6-diaminohexyl)-L-lysine]-neuromedin N (pig spinal cord); H-Lysy(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH. Grade: ≥95% by HPLC. CAS No. 139026-66-7. Molecular formula: C38H66N8O7. Mole weight: 746.96. | |
| JMV 449 acetate | JMV 449 acetate is a potent neurotensin receptor agonist. JMV 449 acetate shows an IC 50 of 0.15 nM for inhibition of 125 I-neurotensin binding to neonatal mouse brain and an EC 50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 acetate has highly potent and long-lasting hypothermic and analgesic effects in the mouse [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 141863-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1256C. | |
| JNJ0966 | JNJ0966 is a highly selective MMP-9 zymogen inhibitor with an IC50 of 440 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 315705-75-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103482. | |
| JNJ-1013 | JNJ-1013 is a potent and selective IRAK1 PROTAC degrader with an IC50s of 72, 443, 1071 nM for IRAK1, IRAK4, VHL FP respectively. JNJ-1013 induces apoptosis and increases the expression of cleavaged PARP. JNJ-1013 decreases the expression IRAK1, p-IKB?, pSTAT3(Tyr705) (Pink: ligand for target protein (HY-138834); black: linker (HY-Y1760); Blue: E3 ligase ligand (HY-112078))[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597343-08-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153188. | |
| JNJ 10181457 | JNJ 10181457. Group: Biochemicals. Alternative Names: 4- [3- [4- [Piperidinyl] but-1-ynyl] benzyl] morpholine. Grades: Highly Purified. CAS No. 544707-19-9. Pack Sizes: 10mg. Molecular Formula: C20H28N2O, Molecular Weight: 312.45. US Biological Life Sciences. | Worldwide |
| JNJ 10191584 maleate | JNJ 10191584 maleate. Group: Biochemicals. Grades: Purified. CAS No. 869497-75-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JNJ 10191584 maleate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| JNJ-10198409 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| JNJ-10198409 | JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor ( IC 50 =2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase ( IC 50 =4.2 nM) and PDGFR-α kinase ( IC 50 =45 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 627518-40-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-W011266. | |
| JNJ-10198409 | JNJ-10198409, also known as RWJ-540973, is an inhibitor of PDGF-BB tyrosine kinase with an IC50 value of 4.2 nM. JNJ-10198409 is a competitive antagonist of the ATP binding and hydrolysis at this receptor, resulting in a dose dependent inhibition of tumor growth and angiogenesis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JNJ-10198409; JNJ 10198409; JNJ10198409; RWJ-540973; RWJ 540973; RWJ540973. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 627518-40-5. Molecular formula: C18H16FN3O2. Mole weight: 325.34. Purity: >98%. IUPACName: N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine. Canonical SMILES: COC1=CC2=C(C=C1OC)CC3=C2NN=C3NC4=CC=CC(F)=C4. Product ID: ACM627518405-1. Alfa Chemistry ISO 9001:2015 Certified. | |
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