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| Product | Description | |
|---|---|---|
| Jasmolin II+ Cinerin II + Pyrethrin II (Mixture) | Jasmolin II+ Cinerin II + Pyrethrin II is a by-product from the purification of Pyrethrin 2 (~30%, Technical Grade) (P991240). Pyrethrin is a pesticide most commonly used around homes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 2.5g. Molecular Formula: C21H28O5; C22H30O5; C22H28O5. US Biological Life Sciences. |  Worldwide |
| jasmonate O-methyltransferase | 9,10-Dihydrojasmonic acid is a poor substrate for the enzyme. The enzyme does not convert 12-oxo-phytodienoic acid (a precursor of jasmonic acid), salicylic acid, benzoic acid, linolenic acid or cinnamic acid into their corresponding methyl esters. Enzyme activity is inhibited by the presence of divalent cations, e.g., Ca2+, Cu2+, Mg2+ and Zn2+. Group: Enzymes. Synonyms: jasmonic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.141. CAS No. 346420-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1737; jasmonate O-methyltransferase; EC 2.1.1.141; 346420-58-4; jasmonic acid carboxyl methyltransferase. Cat No: EXWM-1737. |  |
| Jasmone Cis | Jasmone Cis. CAS No. 488-10-8. FEMA No. 3196. Kosher: Y. VIGON Item # 500192. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Jasmonic acid | Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of α-Linolenic acid (HY-N0728). Jasmonic acid signaling can also induce the MAP kinase cascade pathway, calcium channel, and many processes that interact with signaling molecules [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Jasmonic acid. CAS No. 6894-38-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122464A. |  |
| Jasmonyl ® | Jasmonyl ® (1,3-Nonane Diol Acetate). CAS No. 18871-14-2. Kosher: Y. VIGON Item # 500449. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Jasmopyrane Forte | Jasmopyrane Forte. CAS No. 18871-14-2. VIGON Item # 503232. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasmorange® | Jasmorange® (Satinaldehyde). CAS No. 41496-43-9. FEMA No. 2748. Kosher: Y. VIGON Item # 503005. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasplakinolide | Jasplakinolide acts as an actin stabilizing agent that stabilizes actin filaments and promotes actin polymerization. It is also a potent inhibitor of breast and prostrate carcinoma cell proliferation. It potently competes with phalloidin for actin binding and induces actin polymerization by stimulating actin filament nucleation in vitro. It induces polymerization of monomeric actin into amorphous masses and disrupts actin filaments in vivo. It is cell permeable and affects chromosome movement in studies. It has insecticidal, antiproliferative and fungicidal activity. It is useful for investigating cell processes mediated by actin depolymerization and polymerization. Synonyms: NSC 613009; NSC613009; NSC-613009; [2S-[1(S*),2R*,4E,6S*,8R*]]-N-[2-Bromo-N-[N-(8-hydroxy-2,4,6-trimethyl-1-oxo-4-nonenyl)-L-alanyl]-N-methyl-D-tryptophyl]-3-(4-hydroxyphenyl)-β-alanine ρ-Lactone; 1-Oxa-5,8,11-triazacyclononadecane β-alanine deriv.; (+)-Jasplakinolide; Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]. Grades: ≥97% by HPLC. CAS No. 102396-24-7. Molecular formula: C36H45BrN4O6. Mole weight: 709.67. |  |
| Jasplakinolide | Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone. Product Category: Inhibitors. Appearance: Solid. CAS No. 102396-24-7. Molecular formula: C36H45BrN4O6. Mole weight: 709.7. Purity: 95%+. IUPACName: (4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone. Canonical SMILES: CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C. Product ID: ACM102396247. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Jasplakinolide | Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research. Source:Isolated from Jaspis splendens. Group: Biochemicals. Grades: Highly Purified. CAS No. 102396-24-7. Pack Sizes: 50ug, 100ug. Molecular Formula: C36H45BrN4O6. US Biological Life Sciences. | Worldwide |
| Jatrorrhizine | Botanical Source: Group: Biochemicals. Alternative Names: Neprotine, Yatrorizine, Jateorhizine, Dehydrocorypalmine. Grades: Plant Grade. CAS No. 3621-38-3. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Jatrorrhizine chloride | Jatrorrhizine chloride. Group: Biochemicals. Alternative Names: Neprotine chloride. Grades: Plant Grade. CAS No. 6681-15-8. Pack Sizes: 20mg. Molecular Formula: C20H20ClNO4, Molecular Weight: 373.83. US Biological Life Sciences. | Worldwide |
| Jatrorrhizine chloride | Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities [1]. Jatrorrhizine chloride is a potent and orally active inhibitor of AChE ( IC 50=872 nM) over >115-fold selectivity for BuChE [2]. Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters [3]. Uses: Scientific research. Group: Natural products. CAS No. 6681-15-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg; 50 mg. Product ID: HY-N0740. | |
| Jatrorrhizine Hydrochloride | Jatrorrhizine Hydrochloride (JH), an active component of the traditional Chinese medicinal herb Coptis chinensis, inhibited the proliferation and neovascularization of C8161 human metastatic melanoma cells. The effective inhibitory effects of Jatrorrhizine Hydrochloride on metastatic melanoma cell proliferation and neovascularization with low toxicity suggest that Jatrorrhizine Hydrochloride is a potential new antimelanoma drug candidate. Synonyms: Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, chloride (1:1); Berbinium, 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy-, chloride; Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, monochloride; Jatrorrhizine chloride; Neprotine chloride; NSC 645313. Grades: >98%. CAS No. 6681-15-8. Molecular formula: C20H20ClNO4. Mole weight: 373.83. | |
| Jatrorrhizine hydroxide | Jatrorrhizine?hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities [1]. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE ( IC 50=872 nM) over >115-fold selectivity for BuChE [2]. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters [3]. Uses: Scientific research. Group: Natural products. CAS No. 483-43-2. Pack Sizes: 5 mg; 10 mg; 20 mg; 50 mg. Product ID: HY-N0749A. | |
| Javanicin | It is produced by the strain of Fusarium javanicum, etc. Javanicin is resistant to gram-positive bacteria and mycobacteria. Synonyms: 5,8-Dihydroxy-6-methoxy-3-(2-oxopropyl)-1,4-naphthalenedione; 3-Acetonyl-5,8-dihydroxy-6-methoxy-2-methyl-1,4-naphthoquinone; BRN 2296055. Grades: ≥98% by HPLC. CAS No. 476-45-9. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Javanol ® | Javanol ®. CAS No. 198404-98-7. FEMA No. 4776. Kosher: Y. VIGON Item # 502361. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, sandal cyclopropane. | America & Internationally |
| Jawsamycin | It is produced by the strain of Streptoverticillium fervens. Jawsamycin had strong anti-filamentous fungal activity, and the MIC of Aspergillus Niger, Aureobasidium and Mucor was 0.05 μg/mL. Synonyms: FR-900848; FR900848. CAS No. 120500-69-8. Molecular formula: C32H43N3O6. Mole weight: 565.70. | |
| JB-95 | JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli [1]. Uses: Scientific research. Group: Peptides. CAS No. 1873323-60-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5753. | |
| JBIR-15 | JBIR-15 is an aspochracin derivative metabolized from Aspergillus sclerotiorum. It exhibits antifungal activity against C. albicans. Synonyms: Antibiotic JBIR-15; (2E,4E,6E)-N-[(3S,6S,9S)-3,7-dimethyl-6-(1-methylethyl)-2,5,8-trioxo-1,4,7-triazacyclododec-9-yl]-2,4,6-octatrienamide. Grades: ≥95%. CAS No. 1198588-57-6. Molecular formula: C22H34N4O4. Mole weight: 418.53. | |
| JBJ-04-125-02 | JBJ-04-125-02 is a mutation-selective EGFR inhibitor with anti-tumor activity. Synonyms: JBJ 04-125-02; JBJ04-125-02; JBJ-0412502. Grades: ≥98% by HPLC. CAS No. 2060610-53-7. Molecular formula: C29H26FN5O3S. Mole weight: 543.6. | |
| J(Boc) Acetic acid | A nucleobase for PNA synthesis. Synonyms: N2-(tert-butoxycarbonyl)isocytosin-5-ylacetic acid. Grades: 98%. CAS No. 221362-48-7. Molecular formula: C11H15N3O5. Mole weight: 269.26. | |
| JC-1 | JC-1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CBIC2(3). Product Category: Other Fluorophores. Appearance: Dark violet powder. CAS No. 3520-43-2. Molecular formula: C25H27Cl4IN4. Mole weight: 652.23. Purity: 95%+. IUPACName: 5,6-dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl)prop-2-enylidene]-1,3-diethylbenzimidazole;iodide. Canonical SMILES: CCN1C2=CC(=C(C=C2[N+](=C1/C=C/C=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-]. Product ID: ACM3520432-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide, JC-130B Hercules. | |
| JC-1 | The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590nm) in healthy cells. After cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio. Group: Biochemicals. Alternative Names: 5, 5', 6, 6'-Tetrachloro-1, 1', 3, 3'-tetraethyl benzimidazolyl carbocyanine iodide. Grades: Highly Purified. CAS No. 3520-43-2, 47729-63-5. Pack Sizes: 1mg, 5x1mg. Molecular Formula: C25H27Cl4IN4. US Biological Life Sciences. | Worldwide |
| JC-1 | JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=488 nm, Em=595 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=488 nm, em= 530 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: CBIC2. CAS No. 3520-43-2. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15534. | |
| JCP174 | JCP174 is a depalmitoylase inhibitor that targets TgPPT1. JCP174 enhances Toxoplasma tachyzoite invasion into BSC-1 host cells. Synonyms: 7-amino-4-chloro-3-Propoxyisocoumarin; 7-Amino-4-chloro-3-propoxy-1H-isochromen-1-one. Grades: ≥98%. CAS No. 126062-19-9. Molecular formula: C12H12ClNO3. Mole weight: 253.7. | |
| JCpep7 | JCpep7 is cationic antimicrobial peptide isolated from Jatropha curcas. It has activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Lys-Val-Phe-Leu-Gly-Leu-Lys. Grades: 95.6%. Molecular formula: C40H69N9O8. Mole weight: 804.04. | |
| JD-5037 | Jd-5037 is a peripherally-restricted cannabinoid inverse agonist at CB1 receptors that can be used as an anti-obesity drug, with a 700-fold higher affinity compared to CB2 receptors. Synonyms: JD 5037; JD5037; (S) -2- ( ( (E) - ( (S) -3- (4-chlorophenyl) -4-phenyl-4, 5-dihydro-1H-pyrazol-1-yl) ( (4-chlorophenyl) sulfonamido) methylene) amino) -3-methylbutanamide. Grades: >98%. CAS No. 1392116-14-1. Molecular formula: C27H27Cl2N5O3S. Mole weight: 572.5. | |
| JDTic | A 4-phenylpiperidine derivative, for the κ-opioid receptor. Uses: A selective opioid kappa receptor antagonist. Synonyms: (3R)-7-hydroxy-N-[1-[(3R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide. Grades: ≥98%. CAS No. 361444-66-8. Molecular formula: C28H39N3O3. Mole weight: 465.64. | |
| JDTic dihydrochloride | JDTic dihydrochloride is a highly selective antagonist for the κ-opioid receptor with IC50 value of 0.02nM without affecting the μ- or δ-opioid receptors. It is a 4-phenylpiperidine derivative and distantly structurally related to analgesic drugs such as meperidine and ketobemidone and more closely to the mu opioid antagonist alvimopan. It is structurally distinct from other kappa antagonists such as norbinaltorphimine. It is more selective and potent for KOR activity than other KOR antagonists. It is shown to block the antinociceptive response of nicotine in the tail-flick test with a dose-dependent manner. It can also block the nicotine withdrawal signs in mice vi... it can also block the nicotine withdrawal signs in mice via effecting the expression of a cpa associated with nicotine withdrawal. it is also reported to decrease the number of somatic withdrawal signs in morphine-dependent rats. it may produce antidepressant and anxiolytic effects and may be used in the treatment of addiction to cocaine and morphine. Synonyms: JDTic (2HCl);(3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide hydrochloride;(R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4- . Grades: 95%. CAS No. 785835-79-2. Molecular formula: C28H41Cl2N3O3. Mole weight: 538.55. | |
| JDTic dihydrochloride | JDTic (dihydrochloride) is a potent antagonist of kappa-opioid receptors (KOR) , blocking the κ-agonist U50, 488-induced antinociception. Uses: Scientific research. Group: Signaling pathways. CAS No. 785835-79-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10487. | |
| JE-2147 | JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro. Synonyms: (4R)-3-[(2S,3S)-2-Hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-N-[(2-methylphenyl)methyl]-1,3-thiazolidine-4-carboxamide. CAS No. 186538-00-1. Molecular formula: C32H37N3O5S. Mole weight: 575.7. | |
| Jedi2 | Jedi2 is a Piezo1 channel activator that promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels. Synonyms: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid; 2-Methyl-5-(thien-2-yl)-3-furoic acid; 2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid; 2-methyl-5-(thiophen-2-yl)furan-3-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 651005-90-2. Molecular formula: C10H8O3S. Mole weight: 208.23. | |
| Jellein-1 | Jellein-1 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Pro-Phe-Lys-Ile-Ser-Ile-His-Leu-NH2. Grades: 98.3%. Molecular formula: C47H76N12O9. Mole weight: 952.2. | |
| Jellein-2 | Jellein-2 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Thr-Pro-Phe-Lys-Ile-Ser-Ile-His-Leu. Grades: 97.2%. Molecular formula: C51H83N13O11. Mole weight: 1053.3. | |
| Jellein-3 | Jellein-3 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Glu-Pro-Phe-Lys-Ile-Ser-Ile-His-Leu. Grades: 97.1%. Molecular formula: C52H83N13O12. Mole weight: 1081.3. | |
| Jelleine-I | Jelleine-I is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Pro-Phe-Lys-Leu-Ser-Leu-His-Leu-NH2. Grades: 96.8%. Molecular formula: C47H76N12O9. Mole weight: 952.2. | |
| Jelleine-II | Jelleine-II is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Thr-Pro-Phe-Lys-Leu-Ser-Leu-His-Leu. Grades: 96.4%. Molecular formula: C51H83N13O11. Mole weight: 1053.3. | |
| Jelleine-III | Jelleine-III is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Glu-Pro-Phe-Lys-Leu-Ser-Leu-His-Leu. Grades: 98.0%. Molecular formula: C52H83N13O12. Mole weight: 1081.3. | |
| Jenamidine A | It inhibited K-562 proliferation of chronic myeloid leukemia cells with Gl50 of 1.9 μg/mL. Molecular formula: C13H18N2O3. Mole weight: 250.29. | |
| Jenner's Stain | 25g Pack Size. Group: Stains & Indicators. Formula: N/A. CAS No. 62851-42-7. Prepack ID 83126591-25g. See USA prepack pricing. |  |
| Jenner Stain Certified | Jenner Stain Certified. Group: Biochemicals. Alternative Names: Eosin-Methylene blue. Grades: Highly Purified. CAS No. 62851-42-7. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| Jenner Stain, Certified ≥84% (HPLC) | Jenner Stain, Certified ≥84% (HPLC). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 5g, 25g. US Biological Life Sciences. | Worldwide |
| Jervine | Jervine - Product ID: NST-10-170. Category: Alkaloids. Purity: 98%. Test method: HPLC. CAS No. 469-59-0. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White to off-white powder. Molecular formula: C27H39NO3. Mole weight: 425.61. Storage: +2 +8 °C. |  |
| Jervine | Jervine. Group: Biochemicals. Grades: Purified. CAS No. 469-59-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Jervine | Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC 50 of 500-700 nM [1]. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Ketocyclopamine. CAS No. 469-59-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0836. | |
| Jervine | Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Uses: Antibacterial. Synonyms: Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2, 3, 3'a, 4, 4', 5', 6, 6', 6a, 6b, 7, 7', 7'a, 8, 11a, 11b-hexadecahydro-3-hydroxy-3', 6', 10, 11b-tetramethyl-, (2'R, 3S, 3'R, 3'aS, 6'S, 6aS, 6bS, 7'aR, 11aS, 11bR)-; (2'R, 3S, 3'R, 3'aS, 6'S, 6aS, 6bS, 7'aR, 11aS, 11bR)-2, 3, 3'a, 4, 4', 5', 6, 6', 6a, 6b, 7, 7', 7'a, 8, 11a, 11b-Hexadecahydro-3-hydroxy-3', 6', 10, 11b-tetramethylspiro[9H-benzo[a]fluorene-9, 2'(3'H)-furo[3, 2-b]pyridin]-11(1H)-one; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-; Jervin; NSC 23898; NSC 7520; Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2, 3, 3'a, 4, 4', 5', 6, 6', 6a, 6b, 7, 7', 7'a, 8, 11a, 11b-hexadecahydro-3-hydroxy-3', 6', 10, 11b-tetramethyl-, [3S-(3α, 6aα, 6bβ, 9α(3'S*, 3'aR*, 6'R*, 7'aS*), 11aβ, 11bα)]-. Grades: >98%. CAS No. 469-59-0. Molecular formula: C27H39NO3. Mole weight: 425.60. | |
| Jervine ((3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one) | Has antibacterial properties. Jervine demonstrates teratogenic properties. It is the starting material for C-nor-D-homosteroids. Jervine induces holoprosencephaly and blocks endogenous Sonic hedgehog signaling. Group: Biochemicals. Alternative Names: (3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Jesaconitine | Jesaconitine. Group: Biochemicals. Grades: Highly Purified. CAS No. 16298-90-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C35H49NO12. US Biological Life Sciences. | Worldwide |
| Jfd00244 | JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 96969-83-4. Molecular formula: C30H26N2O4. Mole weight: 478.54. Purity: 0.9803. Canonical SMILES: O=C1C2=C(C=CC=C2)C(C3=C(NCCC4=CC=C(O)C=C4)C=CC(NCCC5=CC=C(O)C=C5)=C13)=O. Product ID: ACM96969834. Alfa Chemistry ISO 9001:2015 Certified. | |
| JFD00244 | JFD00244 is an inhibitor of sirtuin 2 (SIRT2), a NAD+-dependent protein deacetylase. It induces granulocytic differentiation in the acute promyelocytic leukemia (APL) cell line NB4. Synonyms: BML-266; 1,4-Bis[(P-hydroxyphenethyl)amino]-anthraquinone. Grades: ≥95%. CAS No. 96969-83-4. Molecular formula: C30H26N2O4. Mole weight: 478.5. | |
| JF-NP-26 | JF-NP-26 is a photoactive mGlu5 receptor negative allosteric modulator. Activated by visible light, JF-NP-26 releases the active molecule (raseglurant) that blocks the mGlu5 receptor. Synonyms: (7-(Diethylamino)-2-oxo-2H-chromen-4-yl)methyl (2-((3-fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-yl)carbamate. Grades: ≥98% by HPLC. CAS No. 2341841-03-8. Molecular formula: C30H28FN3O4. Mole weight: 513.56. | |
| JG26 | JG26 is an ADAM17 inhibitor, with IC 50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM for ADAM8, ADAM17, ADAM10 and MMP-12, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1464910-32-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120852. | |
| JGB1741 | JGB1741 is a small-molecule inhibitor of SIRT1, a NAD+-dependent class III histone deacetylase (HDAC) which is overexpressed in many cancer cells. JGB1741 shows potent inhibitory effects against the proliferation of human metastatic breast cancer cells, MDA-MB 231. Synonyms: ILS-JGB-1741; N-Benzyl-2-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide. Grades: ≥98%. CAS No. 1256375-38-8. Molecular formula: C27H24N2O2S. Mole weight: 440.6. | |
| JH295 | JH295 is an irreversible, cysteine-targeted inhibitor of the human centrosomal kinase, Nek2. JH295 irreversibly inhibited cellular Nek2 without affecting the mitotic kinases, Cdk1, Aurora B, or Plk1. Moreover, JH295 did not perturb bipolar spindle assembly or the spindle assembly checkpoint. To our knowledge, JH295 is the first small molecule shown to inactivate Nek2 kinase activity in cells. Synonyms: JH 295; JH-295; 3-[(2-Ethyl-4-methyl-1H-imidazole)-5-ylmethylene]-5-[(1-oxo-2-propynyl)amino]-1H-indole-2(3H)-one. CAS No. 1311143-71-1. Molecular formula: C18H16N4O2. Mole weight: 320.35. | |
| JH-II-127 | JH-II-127, a Pyrrolopyrimidine derivative, is a highly potent, selective, and brain penetrant LRRK2 inhibitor, of both wild-type and G2019S mutant LRRK2. IC50: LRRK2-wild-type= 6.6 nM, LRRK2-G2019S= 2.2 nM ,LRRK2-A2016T= 47.7 nM. Synonyms: [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone JH-II-127 (4-((5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxyphenyl)(morpholino)methanone 1700693-08-8 JH-II127 JH-II. CAS No. 1700693-08-8. Molecular formula: C19H21ClN6O3. Mole weight: 416.86. | |
| JH-RE-06 | JH-RE-06. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1361227-90-8. Molecular Formula: C20H16Cl3N3O4. Mole Weight: 468.72. Catalog: APB1361227908. |  |
| JHU-083 | JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1998725-11-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122218. | |
| JHU-16907 | Cas No. 942063-86-7. | |
| JHU-292 | JHU-292 is the prodrug of 6-diazo-5-oxo-L-norleucine (DON), a glutaminase antagonist with therapeutic effect on hematological malignancies. Compared to DON, JH-292 exhibits excellent stability in human plasma and reduced gastrointestinal side effects. It would be metabolized to DON in tumor cells with the tumor cell/plasma DON ratio enhanced 15-fold. Uses: The treatment of hematological malignancies. Synonyms: JHU-292; JHU292. | |
| JHU37160 | JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist. It has high affinity in vitro for hM3Dq and hM4Di (Ki values are 1.9 nM (hM3Dq) and 3.6 nM (hM4Di). Synonyms: JHU 37160; JHU-37160. CAS No. 2369979-68-8. Molecular formula: C19H20ClFN4. Mole weight: 358.84. | |
| JHU395 | JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2079938-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128775. | |
| JHW 007 hydrochloride | JHW 007 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 202645-74-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JHW 007 hydrochloride | The hydrochloride salt form of JHW 007, which is a dopamine uptake inhibitor and could also restrain the effects of cocaine in a dose-dependent manner. Synonyms: JHW 007 hydrochloride; JHW007 hydrochloride; JHW-007 hydrochloride; (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride. Grades: ≥99% by HPLC. CAS No. 202645-74-7. Molecular formula: C24H29F2NO.HCl. Mole weight: 421.95. | |
| JH-X-119-01 | Jh-X-119-01 is a novel potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 irreversibly labels IRAK1 at C302. This compound exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88. Cotreatment of JH-X-119-01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JH-X-119-01; JH-X119-01; JH-X 119-01; JH-X-11901; JH-X11901; JH-X 11901; JHX-11901; JHX11901; JHX 11901. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2227368-54-7. Molecular formula: C25H20N6O3. Mole weight: 452.47. Purity: >98%. IUPACName: N-(4-(3-Acrylamidobenzamido)phenyl)-6-(1H-pyrazol-5-yl)picolinamide. Canonical SMILES: O=C(NC1=CC=C(NC(C2=CC=CC(NC(C=C)=O)=C2)=O)C=C1)C3=NC(C4=CC=NN4)=CC=C3. Product ID: ACM2227368547. Alfa Chemistry ISO 9001:2015 Certified. | |
| JH-X-119-01 | JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice [1]. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC 50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2227368-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103017A. | |
| JH-X-119-01 hydrochloride | JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2591344-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-103017. | |
| JH-X-119-01 hydrochloride | A potent IRAK1 inhibitor. Synonyms: JH-X-119-01 (hydrochloride). CAS No. 2591344-30-6. Molecular formula: C25H21ClN6O3. Mole weight: 488.93. | |
| JI-101 | JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRb), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities. Angiogenesis inhibitor JI-101 binds to and inhibits VEGFR2, PDGFRb and EphB4, which may inhibit tumor angiogenesis and, so, cellular proliferation in tumor cells overexpressing VEGFR2, PDGFRb and EphB4. The receptor tyrosine kinases VEGFR2, PDGFRb and EphB4 may be overexpressed in a number of different cancer cell types and may play crucial roles in tumor angiogenesis. Synonyms: N-[1-[(2-Amino-4-pyridinyl)methyl]-1H-indol-4-yl]-N'-(5-bromo-2-methoxyphenyl)urea; 1-[1-[(2-Aminopyridin-4-yl)methyl]-1H-indol-4-yl]-3-(5-bromo-2-methoxyphenyl)urea; CGI 1842; JI101; JI 101. Grades: 98%. CAS No. 900573-88-8. Molecular formula: C22H20BrN5O2. Mole weight: 466.33. | |
| JIB 04 | JIB 04. Group: Biochemicals. Grades: Purified. CAS No. 199596-05-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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