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| Product | Description | |
|---|---|---|
| N-Trityl Candesartan Methyl Ester Methoxy Analogue | Precursor to Candesartan Cilexetil Methoxy Analogues. Group: Biochemicals. Alternative Names: 2-Methoxy-1-[[2'-(N-trityl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1246815-58-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| N-Trityl Des-4-hydroxy Olmesartan Medoxomil | N-Trityl Des-4-hydroxy Olmesartan Medoxomil is an impurity of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(prop-1-en-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carb. CAS No. 1227626-51-8. Molecular formula: C48H42N6O5. Mole weight: 782.88. |  |
| N-Trityl-deshydroxymethyl Losartan | Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 5-[4'-[(2-Butyl-4-chloro-1H-imidazol-1-yl)methyl][1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-1H-tetrazole. Grades: Highly Purified. CAS No. 1216502-96-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| N-Trityl-D-homoserine lactone | Synonyms: Trt-D-Hse-lactone; Trt-D-homoSer-lactone. CAS No. 299417-08-6. Molecular formula: C23H21NO2. Mole weight: 343.43. | |
| N-Tritylglycine hydrazide | Heterocyclic Organic Compound. Alternative Names: N-TRITYLGLYCINE HYDRAZIDE;TIMTEC-BB SBB007768. CAS No. 116435-38-2. Molecular formula: C21H21N3O. Mole weight: 331.41. Catalog: ACM116435382. |  |
| N-Tritylglycine Hydrazide | White crystalline. CAS No. 116435-38-2. Pack Sizes: 1g. Product ID: FR-0301. M.P. 162-164. Mole weight: 331.42. |  Frinton Laboratories |
| N-Tritylglycine methyl ester | Heterocyclic Organic Compound. Alternative Names: N-TRITYLGLYCINE METHYL ESTER. CAS No. 10065-71-1. Molecular formula: C22H21NO2. Mole weight: 331.41. Catalog: ACM10065711. | |
| N-Trityl-hexahydro-1H-1,4-diazepine, polymer bound | N-Trityl-hexahydro-1H-1,4-diazepine, polymer bound. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| N-Trityl-hexamethylenediamine, polymer bound | N-Trityl-hexamethylenediamine, polymer bound. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| N-Trityl histamine oxalate | N-Trityl histamine oxalate. Group: Biochemicals. Alternative Names: 1-(Triphenylmethyl)-1H-imidazole-4-ethanamine ethanedioate; 2-(1-Trityl-1H-imidazol-4-yl)ethylamine oxalate. Grades: Highly Purified. CAS No. 1187929-12-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C26H25N3O4. US Biological Life Sciences. | Worldwide |
| N-Trityl histamine oxalate | Heterocyclic Organic Compound. Alternative Names: 1-(Triphenylmethyl)-1H-imidazole-4-ethanamine Ethanedioate; 2-(1-Trityl-1H-imidazol-4-yl)ethylamine Oxalate. CAS No. 1187929-12-9. Molecular formula: C26H25N3O4. Mole weight: 443.49. Purity: 0.96. IUPACName: oxalic acid;2-(1-tritylimidazol-4-yl)ethanamine. Catalog: ACM1187929129. | |
| N-Tritylhydrazide hydrochloride | Heterocyclic Organic Compound. Alternative Names: Trityl-hydrazin, Hydrochlorid; trityl-hydrazine, hydrochloride; tritylhydrazine hydrochloride; (triphenylmethyl)hydrazine, hydrochloride; N-Tritylhydrazide hydrochloride. CAS No. 104370-29-8. Molecular formula: C19H19ClN2. Mole weight: 310.83. Purity: 0.96. IUPACName: triphenylmethylhydrazine hydrochloride. Catalog: ACM104370298. | |
| N-Trityl-L-glutamic acid,triethylammonium salt(1:2) | Heterocyclic Organic Compound. Alternative Names: N-Trityl-L-glutamic acid compound with Et3N (1:2);N-TRITYL-L-GLUTAMIC ACID, TRIETHYLAMMONIUM SALT (1:2);TRIETHYLAMMONIUM-N-(TRITYL)-L-GAMMA-GLUTAMATE;Triethylammonium-N-(trityl)-L-g-glutamate;Triethylammonium-N-(triyl)-L-gamma-glutamate. CAS No. 124100-16-9. Molecular formula: C30H38N2O4. Mole weight: 490.63. Catalog: ACM124100169. | |
| N'-Trityl-L-glutamine | Heterocyclic Organic Compound. CAS No. 102747-84-2. Molecular formula: C24H24N2O3. Mole weight: 388.46. Catalog: ACM102747842. | |
| N-Trityl-L-homoserine lactone | Synonyms: Trt-Hse-lactone; Trt-homoSer-lactone. CAS No. 83427-81-0. Molecular formula: C23H21NO2. Mole weight: 343.43. | |
| N-Trityl-L-homoserine triethylamine salt | Heterocyclic Organic Compound. CAS No. 102056-97-3. Molecular formula: C23H23N1O3. Mole weight: 462.62. Catalog: ACM102056973. | |
| N-Trityl Losartan | N-Trityl Losartan. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Losartan Potassium Imp. H (EP) , [2-Butyl-4-chloro-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methanol, Losartan Imp. H (EP). CAS No. 133909-99-6. IUPAC Name: [2-butyl-5-chloro-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol. Molecular Formula: C41H37ClN6O. Mole Weight: 665.23. Catalog: APS133909996. SMILES: CCCCc1nc (Cl)c (CO)n1Cc2ccc (cc2)c3ccccc3c4nnn (n4)C (c5ccccc5) (c6ccccc6)c7ccccc7. Format: Neat. |  |
| N-Trityl Losartan | Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol; Trityllosartan. Grades: Highly Purified. CAS No. 124751-00-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan β-D-glucuronic Acid Methyl Ester (N1, N2 mixture) | Intermediate in the preparation of Losartan metabolites and impurities. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5- β-D-glucuronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl losartan carboxaldehyde | Heterocyclic Organic Compound. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. CAS No. 120568-18-5. Molecular formula: C41H35ClN6O. Mole weight: 663.21. Appearance: Off-White Foam. Purity: 0.96. IUPACName: 2-butyl-5-chloro-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde. Density: 1.221g/cm³. Catalog: ACM120568185. | |
| N-Trityl Losartan Carboxaldehyde | An intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 120568-18-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-Trityl losartan carboxylic acid | N-Trityl losartan carboxylic acid. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid. Grades: Highly Purified. CAS No. 947331-10-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C41H35ClN6O2. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan-d3 Carboxaldehyde | A labeled intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-d3-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan-d3 Carboxylic Acid | A Losartan derivative for treatment of hypertension. Group: Biochemicals. Alternative Names: 2-Butyl-d3-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan-d4 | A protected form of labeled Losartan (an antihypertensive). Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl-d4]-4-yl]methyl]-1H-imidazole-5-methanol; Trityllosartan-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan-d4 Carboxaldehyde | A labeled intermediate in the synthesis of the EXP 3174, a metabolite of Losartan. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Losartan Isomer | Intermediate in the preparation of Losartan impurities. Group: Biochemicals. Alternative Names: 2-Butyl-5-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-4-methanol. Grades: Highly Purified. CAS No. 133727-10-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| N-Trityl-L-proline diethylammonium salt | Synonyms: Trt-Pro-OH DEA; (S)-1-Tritylpyrrolidine-2-carboxylic acid diethylammonium salt. CAS No. 80514-78-9. Molecular formula: C28H34N2O2. Mole weight: 430.58. | |
| N-Trityl-morpholinoguanine | N-Trityl-morpholinoguanine is an extensively studied and widely recognized biomedical compound, exhibiting as a formidable inhibitory compound against select enzymes intricately linked to the pivotal process of DNA synthesis. Synonyms: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-, (2R-cis)-. Grades: ≥95%. CAS No. 140679-49-8. Molecular formula: C29H28N6O3. Mole weight: 508.57. | |
| N-Trityl-morpholino-T-5'-O-phosphoramidite | N-Trityl-morpholino-T-5'-O-phosphoramidite is an irreplaceable and significant compound, serving for facilitating the synthesis of oligonucleotides and DNA-modified compounds. Its extensive adoption within pharmaceutical research, dedicated to the innovation of studying diverse ailments such as cancer, genetic disorders and viral infections. Synonyms: 3- [ [di (propan-2-yl) amino] - [ [ (2S, 6R) -6- (5-methyl-2, 4-dioxopyrimidin-1-yl) -4-tritylmorpholin-2-yl] methoxy] phosphanyl] oxypropanenitrile; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[(2S,6R)-6-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-4-(triphenylmethyl)-2-morpholinyl]methyl ester. Grades: ≥95%. Molecular formula: C38H46N5O5P. Mole weight: 693.78. | |
| N-Trityl-morpholino-U-5'-O-phosphoramidite | N-Trityl-morpholino-U-5'-O-phosphoramidite is a crucial component in the biomedical industry for the synthesis of phosphorothioate oligonucleotides. It finds applications in the development of drugs targeting various diseases like cancer, viral infections and genetic disorders. Synonyms: BP-29998; N-Trityl-morpholino-U-5'-O-phosphoramidite. Grades: ≥95%. Molecular formula: C37H44N5O5P. Mole weight: 669.75. | |
| N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite | N-Trityl-N2-isobutyryl-morpholino-G-5'-O-phosphoramidite is a compound, finding extensive employment in the esteemed realm of biomedical industry. This invaluable compound functions as a phosphoramidite compound, enabling the synthesis of nucleosides and nucleotides with tailored modifications. Its indispensible contribution lies in the facilitation of effective assembly of modified oligonucleotides that possess heightened properties and refined specificity. Synonyms: N-[9-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[(2S,6R)-6-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester. Grades: ≥95%. Molecular formula: C42H51N8O5P. Mole weight: 778.88. | |
| N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite | N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite is a crucial compound used in the synthesis of oligonucleotide mimetics and modified nucleotides for biomedical research. It finds application in the development of novel drugs and therapies for studying various diseases, including cancer, viral infections and genetic disorders. Synonyms: N-[1-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]-2-oxopyrimidin-4-yl]benzamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl 2-cyanoethyl ester. Grades: ≥95%. Molecular formula: C44H49N6O5P. Mole weight: 772.87. | |
| N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite | N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite is a crucial compound used in the biomedical industry for the efficient synthesis of oligonucleotides. This phosphoramidite derivative plays a vital role as a building block during solid-phase synthesis of DNA/RNA fragments, specifically for the research of genetic disorders, viral infections and various types of cancer. Synonyms: N-[9-[(2R,6S)-6-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-4-tritylmorpholin-2-yl]purin-6-yl]benzamide; Phosphoramidous acid, N,N-bis(1-methylethyl)-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl 2-cyanoethyl ester. Grades: ≥95%. Molecular formula: C45H49N8O4P. Mole weight: 796.90. | |
| N-Trityl Olmesartan-d6 Ethyl Ester | N-Trityl Olmesartan-d6 Ethyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Olmesartan Ethyl Ester | N-Trityl Olmesartan Ethyl Ester is an impurity of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid Ethyl Ester. CAS No. 172875-59-1. Molecular formula: C45H44N6O3. Mole weight: 716.87. | |
| N-Trityl Olmesartan Ethyl Ester | N-Trityl Olmesartan Ethyl Ester. Group: Biochemicals. Alternative Names: 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 172875-59-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Olmesartan Medoxomil Methyl Ether | N-Trityl Olmesartan Medoxomil Methyl Ether is an intermediate in the synthesis of Olmesartan Medoxomil (O550000), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Trityl Olmesartan Methyl Ketone | N-Trityl Olmesartan Methyl Ketone is an derivative of Olmesartan Medoxomil (O550000). Olmesartan Medoxomil is an angiotensin II receptor antagonist. Used as an anti-hypertensive agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl O-Methyl Ether Olmesartan Acid | N-Trityl O-Methyl Ether Olmesartan Acid is an intermediate in the synthesis of Olmesartan Acid (O550001), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl O-Methyl Ether Olmesartan Acid Ethyl Ester | N-Trityl O-Methyl Ether Olmesartan Acid Ethyl Ester is an intermediate in the synthesis of Olmesartan Acid (O550001), an angiotensin II receptor antagonist used as an anti-hypertensive agent. Group: Biochemicals. Alternative Names: Ethyl 4-(2-Methoxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trityl-trimethylenediamine, polymer bound | N-Trityl-trimethylenediamine, polymer bound. Group: Biochemicals. Alternative Names: 1,3-Diaminopropane trityl resin; N- (3-Aminopropyl) tritylamine, polymer bound. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| N-Trityl-trimethylenediamine, polymer bound, 0.3-0.8 meq/g (substitution) | N-Trityl-trimethylenediamine, polymer bound, 0.3-0.8 meq/g (substitution). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| N type Bismuth(III) telluride | N type Bismuth(III) telluride. Group: Semiconductor blocks. CAS No. 1304-82-1. |  |
| nTZDpa | nTZDpa. Group: Biochemicals. Grades: Purified. CAS No. 118414-59-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NU1025 | NU1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1025 enhanced the cytotoxicity of the DNA-methylating agent MTIC, gamma-irradiation and bleomycin 3.5-, 1.4- and 2-fold respectively. Synonyms: NU-1025; NU 1025; 8-Hydroxy-2-methylquinazoline-4-one; NSC 696807. Grades: ≥98%. CAS No. 90417-38-2. Molecular formula: C9H8N2O2. Mole weight: 176.17. | |
| NU 1025 | NU 1025. Group: Biochemicals. Grades: Purified. CAS No. 90417-38-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NU1064 | NU1064 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which can potentiate the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1064 potentiated a sublethal concentration of a DNA methylating agent in a concentration-dependent manner. Synonyms: NU-1064; NU 1064; 4-Piperidinol, 1-butyl-4-(2-pyridyl)methyl-, acetate, dihydrochloride. Grades: 98%. CAS No. 63916-38-1. Molecular formula: C9H9N3O. Mole weight: 175.19. | |
| NU1085 | NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. It has been developed to potentiate the cytotoxicity of ionizing radiation and anticancer drugs. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: NU-1085; NU 1085; 2-(4-hydroxyphenyl)-1H-benzo[d]imidazole-7-carboxamide. Grades: 98%. CAS No. 188106-83-4. Molecular formula: C14H11N3O2. Mole weight: 253.26. | |
| NU2058 | NU2058 is a potent CDK inhibitor. which has CDK2 IC(50)=17 microM and CDK1 IC(50)=26 microM. Synonyms: NU2058; NU 2058; NU-2058; O(6)-Cyclohexylmethylguanine. Grades: 0.98. CAS No. 161058-83-9. Molecular formula: C12H17N5O. Mole weight: 247.3. | |
| NU 2058 | NU 2058. Group: Biochemicals. Grades: Purified. CAS No. 161058-83-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NU6027 | NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner. NU6027 attenuated G2/M arrest following DNA damage, inhibited RAD51 focus formation and increased the cytotoxicity of the major classes of DNA-damaging anticancer cytotoxic therapy but not the antimitotic, paclitaxel. In A2780 cells sensitisation to cisplatin was greatest in cells with functional p53 and mismatch repair (MMR) and sensitisation to temozolomide was greatest in p53 mutant cells with functional MMR. Importantly, NU6027 was synthetically lethal when DNA single-strand break repair is impaired either through poly(ADP-ribose) polymerase (PARP) inhibition or defects in XRCC1. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and PARP inhibitors. It provides proof of concept data for clinical development of ATR inhibitors. Synonyms: NU-6027; NU 6027; 2,6-Diamino-4-(cyclohexylmethoxy)-5-nitrosopyrimidine; 6-(Cyclohexylmethoxy)-5-nitroso-2,4-pyrimidinediamine; 4-Cyclohexylmethoxy-2,6-diamino-5-nitrosopyrimidine; 4-Cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine. Grades: ≥98%. CAS No. 220036-08-8. Molecular formula: C11H17N5O2. Mole weight: 251.29. | |
| NU 6102 | NU 6102 is a potent inhibitor of CDK1 and CDK2 with Ki values of 9 and 6 nM and IC50 values of 9.5 and 5.4 nM, respectively. NU 6102 inhibits Cdk4 activity with IC50 value of 1.6 μM. Synonyms: NU-6102; NU6102; 4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]benzenesulfonamide. Grades: ≥95%. CAS No. 444722-95-6. Molecular formula: C18H22N6O3S. Mole weight: 402.5. | |
| NU6102 (O6-Cyclohexylmethyl-2- (4-sulfamoylanilino) purine) | Potent CDK1/cyclin B (IC50 = 9.5nM) and CDK2/cyclin A3 (IC50 = 5.4nM) inhibitor. 1,000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6uM), DYRK1A (IC50 = 0.9uM), PDK1 (IC50 = 0.8uM) and ROCKII (IC50 = 0.6uM). Inhibits cell growth. Group: Biochemicals. Alternative Names: O6-Cyclohexylmethyl-2- (4-sulfamoylanilino) purine. Grades: Highly Purified. CAS No. 444722-95-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H22N6O3S, Molecular Weight: 402.5. US Biological Life Sciences. | Worldwide |
| NU6140 | NU6140 is a cyclin-dependent kinase 2 (cdk2) inhibitor, and induces cell-cycle arrest at the G2-M phase. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Synonyms: Cdk2 inhibitor IV; NU 6140. Grades: 98%. CAS No. 444723-13-1. Molecular formula: C23H30N6O2. Mole weight: 422.53. | |
| NU 6140 | NU 6140. Group: Biochemicals. Grades: Purified. CAS No. 444723-13-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NU7026 | NU7026 is a potent DNA-PK inhibitor with IC50 value of 0.23±0.01 μM. NU7026 has been described to increase precise genome-editing efficiency in pluripotent stem cells. Synonyms: DNA-PK Inhibitor II; 2-(Morpholin-4-yl)-benzo[h]chromen-4-one; 2-morpholin-4-ylbenzo[h]chromen-4-one. Grades: >98%. CAS No. 154447-35-5. Molecular formula: C17H15NO3. Mole weight: 281.311. | |
| NU 7026 | NU 7026. Group: Biochemicals. Grades: Purified. CAS No. 154447-35-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NU-7031 | NU-7031 is a potent DNA-PK inhibitor with potential anticancer activity. Synonyms: NU7031; NU 7031. Grades: 98%. CAS No. 79105-88-7. Molecular formula: C14H15NO4. Mole weight: 261.28. | |
| NU-7107 | NU-7107 is a potent DNA-PK inhibitor with potential anticancer activity. Synonyms: NU 7107; NU7107. Grades: 98%. CAS No. 503465-21-2. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| NU-7199 | NU-7199 is a potent DNA-PK inhibitor with potential anticancer activity. Synonyms: NU 7199; NU7199. Grades: 98%. CAS No. 69541-04-4. Molecular formula: C17H17NO4. Mole weight: 299.33. | |
| NU-7200 | NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity. Synonyms: NU 7200; NU7200. Grades: 98%. CAS No. 842122-14-9. Molecular formula: C17H17NO4. Mole weight: 299.326. | |
| NU7441 | NU7441 is a highly potent and selective DNA-PK inhibitor (IC50=14 nM), exhibiting ATP-competitive inhibition kinetics. NU7441 increased the cytotoxicity of ionizing radiation and etoposide in SW620, LoVo, and V3-YAC cells but not in V3 cells, confirming that potentiation was due to DNA-PK inhibition. NU7441 substantially retarded the repair of ionizing radiation-induced and etoposide-induced DSB. NU7441 appreciably increased G(2)-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. In mice bearing SW620 xenografts, NU7441 concentrations in the tumor necessary for chemopotentiation in vitro were maintained for at least 4 hours at nontoxic doses. NU7441 increased etoposide-induced tumor growth delay 2-fold without exacerbating etoposide toxicity to unacceptable levels. In conclusion, NU7441 shows sufficient proof of principle through in vitro and in vivo chemosensitization and radiosensitization to justify further development of DNA-PK inhibitors for clinical use. Synonyms: NU7441; NU-7441; NU 7441; KU-57788; KU 57788; KU57788. Grades: 98%. CAS No. 503468-95-9. Molecular formula: C25H19NO3S. Mole weight: 413.49. | |
| NU 7441 | A potent novel DNA-dependent protein kinase inhibitor models of human cancer. Antitumor agent. Group: Biochemicals. Alternative Names: 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; KU 57788. Grades: Highly Purified. CAS No. 503468-95-9. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??NO?S, Molecular Weight: 413.49. US Biological Life Sciences. | Worldwide |
| NU 9056 | NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 = < 2, 60, 36, and>100 μM for KAT5, p300, pCAF and GCN5, respectively). NU 9056 treatment inhibited cellular proliferation in a panel of prostate cancer cell lines (50% growth inhibition, 8-27 μM) and induced apoptosis via activation of caspase 3 and caspase 9 in a concentration- and time-dependent manner. Also, decreased androgen receptor, prostate specific antigen, p53 and p21 protein levels were demonstrated in response to treatment with NU 9056. Synonyms: NU 9056; NU9056; NU-9056; 5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole. CAS No. 1450644-28-6. Molecular formula: C6H4N2S4. Mole weight: 232.37. | |
| NU 9056 | NU 9056. Group: Biochemicals. Grades: Purified. CAS No. 1450644-28-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NUAK family SNF1-like kinase 2 (446-455) | NUAK family SNF1-like kinase 2 (446-455) is a peptide derived from NUAK family SNF1-like kinase 2. NUAK family SNF1-like kinase 2 induces cell-cell detachment by increasing F-actin conversion to G-actin. Synonyms: Omphalocele kinase 2 (446-455). | |
| nuatigenin 3β-glucosyltransferase | Some other sapogenins can act as glucosyl acceptors. Involved in the biosynthesis of plant saponins. Not identical with EC 2.4.1.173 (sterol 3β-glucosyltransferase) or EC 2.4.1.193 (sarsapogenin 3β-glucosyltransferase). Group: Enzymes. Synonyms: uridine diphosphoglucose-nuatigenin glucosyltransferase. Enzyme Commission Number: EC 2.4.1.192. CAS No. 108891-57-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2419; nuatigenin 3β-glucosyltransferase; EC 2.4.1.192; 108891-57-2; uridine diphosphoglucose-nuatigenin glucosyltransferase. Cat No: EXWM-2419. |  |
| NUC-7738 | NUC-7738, an aryloxy phosphoramidate of 3-Deoxyadenosine, is a 5-aryloxy phosphoramidate prodrug of 3-Deoxyadenosine (3-dA). NUC-7738 has potent cytotoxic activity against a panel of hematological cancer cell lines. NUC-7738 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2348493-39-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136506. |  |
| Nuciferine | Nuciferine. Group: Biochemicals. Alternative Names: Sanjoinine E. Grades: Plant Grade. CAS No. 475-83-2. Pack Sizes: 20mg. Molecular Formula: C19H21NO2, Molecular Weight: 295.375999999999. US Biological Life Sciences. | Worldwide |
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