A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PI3Kα inhibitor 1 is an inhibitor of PI3Kα as well as HDAC and probably have antineoplastic activity. IC50: <0.1 μM. Uses: Pi3kα inhibitor 1 is an inhibitor of pi3kα as well as hdac and probably have antineoplastic activity. Synonyms: PI3Kα inhibitor 1; MDK9521; MDK-9521; MDK 9521; PI3Kα-IN-243; 5-Pyrimidinecarboxamide, N-hydroxy-2-[methyl[[2-[6-(methylamino)-3-pyridinyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]amino]-. Grades: 98%. CAS No. 1235449-52-1. Molecular formula: C23H25N9O3S. Mole weight: 507.57.
PI3Kα/mTOR-IN-1
PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR (Kis= 10.6 nM and 12.5 nM for mTOR and PI3Kα, respectively). Synonyms: Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)-. CAS No. 1013098-90-2. Molecular formula: C16H18N6O. Mole weight: 310.35.
PI3Kδ/γ-IN-1
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1980884-01-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144993.
PI3Kδ-IN-16
PI3Kδ-IN-16 is a potent and selective inhibitor of PI3K&delta. PI3Kδ-IN-16 has a strong anti-proliferative effect on cells, causing cell cycle arrest and inducing apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766437-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155232.
PI3Kδ-IN-2
PI3Kδ-IN-2 is a potent and selective inhibitor ofPI3Kδ (IC50= 6.4 M). CAS No. 1702816-75-8. Molecular formula: C28H37FN6O5S. Mole weight: 588.69.
PI3Kδ-IN-7n
PI3Kδ-IN-7n is a potent and highly selective inhibitor of PI3Kδ with IC50 value of 0.9 nM. Synonyms: Selective PI3Kδ Inhibitor 1. CAS No. 2088525-31-7. Molecular formula: C23H20FN7O. Mole weight: 429.45.
PI3k(delta) inhibitor 1
PI3kδ inhibitor 1 is a potent and selective inhibitor of isoform of PI3Kδ; useful for treating disorders mediated by lipid kinases such as inflammation, immunol disorders, and cancer. Synonyms: 2-[1-[[2-(5-Fluoro-1H-indol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-yl]propan-2-ol. Grades: >98%. CAS No. 1332075-63-4. Molecular formula: C28H33FN6O2. Mole weight: 504.6.
PI3K-IN-32
PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC 50 of 6.85 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371934-59-7. Pack Sizes: 5 mg. Product ID: HY-103030.
PI3K-IN-46
PI3K-IN-46 (Intermediate 4) is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304645-61-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-48869.
PI3-Kinase α Inhibitor 2
PI3-Kinase α (PI3Kα) inhibitor 2 is a potent inhibitor of PI3K p110α (IC50 = 2 nM) with selectivity for p110α over p110β, p110γ, and PI3K C2β (IC50s = 16, 660, and 220 nM, respectively). Synonyms: PI3Kα Inhibitor 2; Phosphatidylinositol 3-Kinase α Inhibitor 2; Compound 15e; 3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol. Grades: ≥98%. CAS No. 371943-05-4. Molecular formula: C16H15N3O2S. Mole weight: 313.4.
PI3-Kinase α Inhibitor 2 hydrochloride
PI3-Kinase α (PI3Kα) inhibitor 2 is a potent inhibitor of PI3K p110α (IC50 = 2 nM) with selectivity for p110α over p110β, p110γ, and PI3K C2β (IC50s = 16, 660, and 220 nM, respectively). Synonyms: Phosphatidylinositol 3-Kinase α Inhibitor 2; PI3Kα Inhibitor 2; 3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol hydrochloride. Grades: ≥98%. CAS No. 1188890-32-5. Molecular formula: C16H15N3O2S·2HCl. Mole weight: 386.3.
PI 3-K Inhibitor XVIII (p110 beta-G beta gamma Interaction Inhibitor peptide, Cell-permeable, Myr-N-KAAEIASSDSANVSSRGGKKFL PV-NH2)
An N-myristoylated cell-permeable PI 3-K p110 beta-derived G beta-gamma-binding peptide (aa514-537 in p110 beta C2-helical linker region) that prevents G beta-gamma-, but not RTK-, mediated p100 beta activation both in cell-free assays (1uM) and in cultures (30uM in p110 beta/p85/Akt/G beta-gamma-transfected HEK 293E cells) without affecting basal p100 beta activity, p110 beta-Rab5 interaction, nor G beta-gamma-dependent activation of adenylyl cyclase or p101-p110-gamma dimer. The ATP-competitive p110 beta inhibitior TGX-221 can be used in conjunction for studying G beta-gamma dependency of p110 beta-mediated cellular functions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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PI3Ky inhibitor 1
PI3Ky inhibitor 1 is a potent PI3Ky inhibitor. Synonyms: 1172118-03-4; PI3Kgamma inhibitor 1; CHEMBL2216897N-(6-(4-Amino-1-((8-methyl-1-oxo-2-(o-tolyl)-1,2-dihydroisoquinolin-3-yl)-methyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]thiazol-2-yl)acetamide; N-[6-[4-amino-1-[[8-methyl-2-(2-methylphenyl)-1-oxoisoquinolin-3-yl]methyl]pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzothiazol-2-yl]acetamide. Grades: >98%. CAS No. 1172118-03-4. Molecular formula: C32H26N8O2S. Mole weight: 586.67.
PI4KIIIbeta-IN-10, a potent anti-viral agent, is a highly PI4KIIIβ inhibitor with weak inhibition of PI3KC2γ (IC50 ~1 μM), PI3Kα (~10 μM), and PI4KIIIα (~3 μM), and <20% inhibition at concentrations up to 20 μM for PI4K2α, PI4K2β, and PI3K&beta. Synonyms: N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide PI4KIIIbeta-IN-10 SCHEMBL14851574. CAS No. 1881233-39-1. Molecular formula: C22H25N3O5S2. Mole weight: 475.58.
PI4KIIIbeta-IN-9
PI4KIIIbeta-IN-9, a thiazole derivative, is a selective PI4KIIIβ inhibitor over PI3Kγ (>140-fold) and PI3Kδ (>20-fold). Studies shows that this compounds may be formulated or provided to a subject in combination with a second anti-infective agent. IC50: P. Synonyms: N- [5- [3- [ (4-hydroxyphenyl) sulfamoyl] -4-methoxyphenyl] -4-methyl-1, 3-thiazol-2-yl] cyclopentanecarboxamidePI4KIIIbeta-IN-9SCHEMBL14851744CS-5620; HY-19798; CS 5620; HY 19798; CS5620; HY19798; 5S8. CAS No. 1429624-84-9. Molecular formula: C23H25N3O5S2. Mole weight: 487.59.
PI4KIII β inhibitor 3
The most effective test compound, the compound of formula 3 (PI4KIII beta inhibitor 3), inhibited IL2 and IFNy secretion with IC50 values of less than 1 nM in each case. Thus, the compound of formula (3) was shown to be as effective at inhibiting IL2 and IFNy secretion as conventional immunosuppressants such as cyclosporine A. IC50 on IFNy and IL-2 release of Cyclosporine A are 2nM and less than 1 nM respectively. Twelve animals received daily treatment with vehicle (1%methylcellulose), twelve others received PI4KIII beta inhibitor 3 at 40 mg/kg/d in 1% methylcellulose. Synonyms: PI4KIII beta inhibitor 3. Grades: >98%. CAS No. 1245319-54-3. Molecular formula: C22H22N8OS. Mole weight: 446.53.
PI5P4Kα-IN-1 (Compound 13) is a PI5P4K inhibitor ( IC 50 : 2 and 9.4 μM for PI5P4Kα and PI5P4Kβ). PI5P4Kα-IN-1 can be used for research of cancer, metabolic and immunological disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2428737-31-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153531.
PI5P4Kγ-IN-1
PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419358-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153789.
PI 828
PI 828. Group: Biochemicals. Grades: Purified. CAS No. 942289-87-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
PI 828
PI 828 is a cell permeable 4'-amino derivative which inhibits the p110α, p110β, p110δ, and p110γ subunits of PI 3-kinase. PI-828 is a potent inhibitor of phosphatidylinositol 3-kinase (PI3K; IC50s = 9.8, 183, 227, and 1,967 nM for p110β, p110α, p110δ, and p110γ, respectively) that displays higher potency than LY 294002. Synonyms: LY294002,4'-NH2; PI-828; PI 828; PI828. 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one. Grades: ≥99% by HPLC. CAS No. 942289-87-4. Molecular formula: C19H18N2O3. Mole weight: 322.36.
PIANO n-Paraffins Mixture 99
PIANO n-Paraffins Mixture 99. Uses: For analytical and research use. Group: Hydrocarbons & petrochemicals. Catalog: APS011260. Format: Mixture. Shipping: Room Temperature.
Piboserod
Piboserod is a highly and potent selective 5-HT4 receptor antagonist which as been studied in vitro as well as in vivo as a pharmacological tool to evaluate the pathophysiological role of the 5-HT4 receptor in human gastrointestinal pathophysiology. Synonyms: N-[(1-butylpiperidin-4-yl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide Piboserod UNII-4UQ3S81B25 SB-207266 152811-62-6 SB207256 SB 207266 N-[(1-butylpiperidin-4-yl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide Pibosero. Grades: 95%. CAS No. 152811-62-6. Molecular formula: C22H31N3O2. Mole weight: 369.51.
Piboserod
Piboserod (SB 207266) is a 5-HT4 selective inhibitor of the serotonin receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-207266. CAS No. 152811-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15574.
Piboserod hydrochloride
Piboserod hydrochloride is a selective 5-HT4 antagonist. Synonyms: Piboserod HCl; N-[(1-butylpiperidin-4-yl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide hydrochloride. Grades: 99%. CAS No. 178273-87-5. Molecular formula: C22H31N3O2.HCl. Mole weight: 405.96.
Pibrentasvir
Pibrentasvir is an antiviral agent that inhibits HCV non-structural protein 5A (NS5A). It inhibits HCV RNA replication and viron assembly. In combination with glecaprevir, a HCV NS3/4A protease inhibitor, pibrentasvir is used to treat patients with HCV infections who experienced therapeutic failure from other NS5A inhibitors. Grades: ≥98%. CAS No. 1353900-92-1. Molecular formula: C57H65F5N10O8. Mole weight: 1113.18.
Pibrentasvir
Pibrentasvir is a novel and pan-genotypic hepatitis C virus ( HCV ) NS5A inhibitor with EC 50 s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-530. CAS No. 1353900-92-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101662.
PI-BT
PI-BT is a benzothiadiazole based conducting polymer that can be used as an acceptor molecule for the fabrication of organic photovoltaic cells. It can be used with a variety of donor molecules, which include P3HT, NI-BT, and CTS-(FBTTh2), to form a high packed semiconducting polymer. It shows a power conversion efficiency of 3.7%.[. Uses: A electron-deficient molecule used in solution-processed organic photovoltaics (opv) has achieved power coversion efficiency (pce) 3.7%. the most promising non-fullerene acceptor material for application in opvs. Group: Fullerene acceptor materials. Alternative Names: 5,5'-(2,1,3-Benzothiadiazole-4,7-diyldi-2,1-ethenediyl)bis[2-hexyl-1H-isoindole-1,3(2H)-dione]. CAS No. 1350842-85-1. Canonical SMILES: O=C1N (CCCCCC)C (C2=C1C=CC=C2/C=C/C3=CC=C (/C=C/C4=CC=CC (C (N5CCCCCC)=O)=C4C5=O)C6=NSN=C36)=O. Catalog: ACM1350842851.
Picamilon
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid. CAS No. 34562-97-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-107482.
Picankibart
Picankibart is a mouse-derived IgG1κ antibody targeting IL23A [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2622900-74-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990057.
Picaridin
Picaridin,also known as Icaridin, KBR 3023, under the INCI name hydroxyethyl isobutyl piperidine carboxylate, and the trade names Bayrepel and Saltidin, is an insect repellent that is effective against a range of arthropods, including mosquitoes and ticks. Uses: Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources; insect repellent. Synonyms: KBR 3023; KBR-3023; KBR3023. ICARIDIN;1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine;1-(1-methylpropoxycarbonyl)-2-(2-hydroxyethyl)piperidine;1-methylpropyl2-(2-hydroxyethyl)-1-piperidinecarboxylate;2-(2-hydroxyethyl)-1-piperidinecarboxylicaci1-methylpropylester. Grades: 98%. CAS No. 119515-38-7. Molecular formula: C12H23NO3. Mole weight: 229.32.
Picaridin
Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Insect repellent. Picaridin is an insect repellent that is effective against a range of arthropods, including mosquitoes and ticks.1,2 It shows synergy with the non-pyrethroid insecticide propoxur both in killing and repelling mosquitoes.3 Picaridin and other insect repellents have been shown to act as either agonists or antagonists at insect olfactory receptors.4,5. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-propyl Ester; Icaridin; KBR 3023; Bayrepel. Grades: Highly Purified. CAS No. 119515-38-7. Pack Sizes: 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Picaridin
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial , anticandidal and antifungal properties [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lcaridin. CAS No. 119515-38-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-116144.
Picaridin-d3
Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-d3-propyl Ester; Icaridin-d3; KBR 3023-d3; Bayrepel-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Piceain 1
Piceain 1 is an antimicrobial peptide found in Picea sitchensis, and has activity against E.coli, P.aerμginosa, S.aureus and fungus C.albicans. It shows weak hemolysis activity. Synonyms: H-Lys-Ser-Leu-Arg-Pro-Arg-Cys-Trp-Ile-Lys-Ile-Lys-Phe-Arg-Cys-Lys-Ser-Leu-Lys-Phe-OH; L-lysyl-L-seryl-L-leucyl-L-arginyl-L-prolyl-L-arginyl-L-cysteinyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-lysyl-L-phenylalanyl-L-arginyl-L-cysteinyl-L-lysyl-L-seryl-L-leucyl-L-lysyl-L-phenylalanine. Grades: ≥96%. Molecular formula: C118H197N35O23S2. Mole weight: 2538.18.
Piceain 2
Piceain 2 is an antimicrobial peptide found in Picea sitchensis, and has activity against E.coli, P.aeruginosa, S.aureus and fungus C.albicans. It shows weak hemolysis activity. Synonyms: H-Arg-Pro-Arg-Cys-Trp-Ile-Lys-Ile-Lys-Phe-Arg-Cys-Lys-Ser-Leu-Lys-Phe-OH; L-arginyl-L-prolyl-L-arginyl-L-cysteinyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-lysyl-L-phenylalanyl-L-arginyl-L-cysteinyl-L-lysyl-L-seryl-L-leucyl-L-lysyl-L-phenylalanine. Grades: ≥95%. Molecular formula: C103H169N31O19S2. Mole weight: 2209.77.
Piceatannol
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) [1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties [2]. Piceatannol induces apoptosis in DLBCL cell lines [3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Astringenin; trans-Piceatannol. CAS No. 10083-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13518.
Piceatannol
Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. Neuoprotective. Adipogenesis inhibitor. Promotes glucose uptake, AMPK phosphorylation and GLUT4 translocation. Group: Biochemicals. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Piceatannol 3'-O-glucoside
Piceatannol 3'-O-glucoside. Group: Biochemicals. CAS No. 94356-26-0. Pack Sizes: 5mg. US Biological Life Sciences.
A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M)1. Stimulates Sirt12. Group: Biochemicals. Alternative Names: SIRT1 Activator,3,3?,4,5?-Tetrahydroxy-transstilbene. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
Piceatannol (trans-Picetannol, Astringenin)
Cell-permeable. Kartogenin promotes the differentiation of multipotent mesenchymal stem cells into chondrocytes (EC50 = 100nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis. Group: Biochemicals. Alternative Names: trans-3,3',4,5'-Tetrahydroxystilbene. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
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Picein
Picein, isolated from Picrorhiza kurroa , is a naturally occurring antioxidant [1]. Uses: Scientific research. Group: Natural products. CAS No. 530-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8698.
Picene (purified by sublimation)
Picene (purified by sublimation). Group: Electronic materials. Alternative Names: Benzo[a]chrysene (purified by sublimation) (>99.9%). CAS No. 213-46-7. Product ID: picene. Molecular formula: 278.35. Mole weight: C22H14. C1=CC=C2C (=C1)C=CC3=C2C=CC4=C3C=CC5=CC=CC=C54. InChI=1S/C22H14/c1-3-7-17-15 (5-1)9-11-21-19 (17)13-14-20-18-8-4-2-6-16 (18)10-12-22 (20)21/h1-14H. GBROPGWFBFCKAG-UHFFFAOYSA-N. >99.9%(GC).
Picene (purified by sublimation) (>99.9%)
Picene (purified by sublimation) (>99.9%). Group: other material building blockscarbon nano materials electronic materials molecular conductorsorganic field effect transistor (ofet) materials. CAS No. 213-46-7. Product ID: picene. Molecular formula: 278.3g/mol. Mole weight: C22H14. C1=CC=C2C (=C1)C=CC3=C2C=CC4=C3C=CC5=CC=CC=C54. InChI=1S/C22H14/c1-3-7-17-15 (5-1)9-11-21-19 (17)13-14-20-18-8-4-2-6-16 (18)10-12-22 (20)21/h1-14H. GBROPGWFBFCKAG-UHFFFAOYSA-N.
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 97230-47-2. Pack Sizes: 10mg. US Biological Life Sciences.
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Picfeltarraenin IA
Picfeltarraenin IA is a naturally occurring triterpenoid glycoside that acts as an AChE inhibitior. It also inhibits PI3K and EGFR. CAS No. 97230-47-2. Molecular formula: C41H62O13. Mole weight: 762.92.
Picfeltarraenin IB
Picfeltarraenin IB. Group: Biochemicals. Grades: Plant Grade. CAS No. 97230-46-1. Pack Sizes: 5mg. Molecular Formula: C42H64O14, Molecular Weight: 792.96. US Biological Life Sciences.
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Picfeltarraenin IB
Picfeltarraenin IB is a triterpenoid Picria isolated from felterrae Lour. Synonyms: HY-N2211. Grades: 98%. CAS No. 97230-46-1. Molecular formula: C42H64O14. Mole weight: 792.95.
Picfeltarraenin IV
Picfeltarraenin IV. Group: Biochemicals. Grades: Plant Grade. CAS No. 184288-35-5. Pack Sizes: 5mg. Molecular Formula: C47H72O18, Molecular Weight: 925.08. US Biological Life Sciences.
Worldwide
Picfeltarraenin X
Picfeltarraenin X. Group: Biochemicals. Grades: Plant Grade. CAS No. 1391826-61-1. Pack Sizes: 5mg. Molecular Formula: C36H54O11, Molecular Weight: 662.82. US Biological Life Sciences.
Worldwide
Picfeltarraenin X
Picfeltarraenin X is a triterpenoid compound isolated from the herbs of Picria felterrae Lour. Picfeltarraenin X exhibits inhibitory effect against AChE. Synonyms: (2beta,3alpha,9beta,10alpha,16alpha)-2-(beta-D-Glucopyranosyloxy)-20,24-epoxy-3,16-dihydroxy-9-methyl-19-norlanosta-5,23-diene-11,22-dione. Grades: >98%. CAS No. 1391826-61-1. Molecular formula: C36H54O11. Mole weight: 662.817.
A cell-permeable acryloylcarbamate compound that selectively targets the PDZ (PSD-95/Discs-large/ZO-1 homology) domain of PICK1 (protein interacting with C kinase 1), but not those of PSD-95 (postsynaptic density protein 95) and GRIP1 (glutamate receptor interacting protein 1), effectively competing against dopamine transporter/DAT (Ki ~10uM), GluR2 (Ki ~10uM), and mRluR7a, c-terminus binding to PICK1 PDZ. Shown to accelerate internalized GluR2 surface recycling and suppress both long-term depression and potentiation in rat and murine hippocampal neurons. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Piclamilast
Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor (IC50 = 1 nM at PDE4 from human neutrophils) with >19,000-fold selectivity over other PDE isoenzymes. Uses: Phosphodiesterase 4 inhibitors. Synonyms: Piclamilast; RP-73401; RP 73-401; RP 73401; RP 73 401; RP73401; RP 73401; 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide; N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide. Grades: ≥99% by HPLC. CAS No. 144035-83-6. Molecular formula: C18H18Cl2N2O3. Mole weight: 381.25.
Piclamilast
Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC 50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 73401; RPR 73401. CAS No. 144035-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12887.
Piclamilast
Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor. Piclamilast may offer therapeutic strategies in respiratory diseases, including asthma and chronic obstructive pulmonary disease. Piclamilast may also provide a treatment option for pre-term infants with bronchopulmonary dysplasia (BPD). Group: Biochemicals. Alternative Names: 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide; N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide; RP 73401; RPR 73401. Grades: Highly Purified. CAS No. 144035-83-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Piclidenoson
Piclidenoson (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IB-MECA; CF-101. CAS No. 152918-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13591.
Picloram
Picloram is a systemic herbicide used for general woody plant control. Grades: ≥95% by HPLC. CAS No. 1918-2-1. Molecular formula: C6H3Cl3N2O2. Mole weight: 241.46.
Picloram
Picloram is used as a herbicide. Studies show that Picloram can reduce seed germination rate and vigor as well as seedling growth in Bidens pilosa L. Group: Biochemicals. Grades: Highly Purified. CAS No. 1918-2-1. Pack Sizes: 1g, 5g. Molecular Formula: C6H3Cl3N2O2. US Biological Life Sciences.
Worldwide
Picloram
25g Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C6H3Cl3N2O2. CAS No. 1918-2-1. Prepack ID 90028337-25g. Molecular Weight 241.46. See USA prepack pricing.
Picloram
Picloram is a synthetic auxin herbicide that is widely used to control dicotyledonous weed [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1918-2-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B2034.
Picloram (Standard)
Picloram (Standard) is the analytical standard of Picloram. This product is intended for research and analytical applications. Picloram is an auxinic herbicide that is widely used for controlling broad leaf weeds [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1918-2-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2034R.
Picloxydine
Picloxydine, a heterocyclic biguanide, has antibacterial and antiplaque properties. In vitro studies have shown that the antibacterial properties of chlorhexidine and picloxydine are similar. Synonyms: 1-N', 4-N'-bis[N'- (4-chlorophenyl) carbamimidoyl]piperazine-1, 4-dicarboximidamide; 1, 1- (p-chlorophenylguanidinoformimidonyl) bis piperazine picloxidine; picloxydine; picloxydine dihydrochloride; Vitabact. CAS No. 5636-92-0. Molecular formula: C20H24Cl2N10. Mole weight: 475.38.
Picolinamide
Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Picolinamide. CAS No. 1452-77-3. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g; 50 g. Product ID: HY-101020.
Picolinamide
Picolinamide acts as an inhibitor of poly (ADP-ribose) synthetase (PARP) of nuclei from rat pancreatic islet cells. Synonyms: pyridine-2-carboxamide. CAS No. 1452-77-3. Molecular formula: C6H6N2O. Mole weight: 122.12.
Picoline-4-N-Oxide
Picoline-4-N-Oxide. CAS No. 1003-67-4. Categories: 4-picoline-n-oxide.
Pennsylvania PA
Picolinic acid
100g Pack Size. Group: Building Blocks, Organics, Pyridines. Formula: C6H5NO2. CAS No. 98-98-6. Prepack ID 23001678-100g. Molecular Weight 123.11. See USA prepack pricing.