A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A highly selective antagonist for NR2B subunit containing nMDA receptors (IC50 = 0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research. Group: Biochemicals. Grades: Highly Purified. CAS No. 134234-12-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CP-10447
An inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly. Group: Biochemicals. Alternative Names: 3-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone; CP 10447; 3-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 843-93-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-105696
CP-105696, a chromen derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied against sorts of nflammatory disease. Uses: Leukotriene antagonists. Synonyms: CP-105696; UNII-Z7354TW4BM; CP-105,696; CHEMBL51770; CP 105696; Z7354TW4BM; 1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]-3,4-dihydro-2H-chromen-7-yl]cyclopentane-1-carboxylic acid. Grades: 98%. CAS No. 158081-99-3. Molecular formula: C28H28O4. Mole weight: 428.53.
CP-114271
CP-114271, a thiazole derivative, has been found to be a β3 adrenergic receptor agonist that was once studied in obesity therapy. Synonyms: CP-114271; CP 114271; CP114271; UL-TG 307; UL-TG-307; UNII-CY8W406YBX.; UL-TG 307; UL-TG-307; CY8W406YBX; Acetic acid, (4- ( (2R) -2- ( ( (2S) -2-hydroxy-2- (2- (trifluoromethyl) -4-thiazolyl) ethyl) amino) propyl) phenoxy) -. Grades: 98%. CAS No. 162326-86-5. Molecular formula: C17H19F3N2O4S. Mole weight: 404.40.
CP 115953
CP 115953 is a Type II DNA topoisomerase inhibitor originated by Pfizer. CP 115953 inhibits topoisomerase II activity via an interaction with the enzyme and not by DNA unwinding. It can stimulate cytokine production by lymphocytes. Research for treatment of cancer was discontinued. Uses: Cancer. Synonyms: CP 115953; CP115953; CP-115953; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-3-quinolinecarboxylic acid. Grades: 98%. CAS No. 136440-70-5. Molecular formula: C19H13F2NO4. Mole weight: 357.31.
CP 117227
CP 117227, a dibenzocyclohepten derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in studies of anticancer. Synonyms: CP 117227; CP-117227; CP117227; 1-Piperazineethanol, 4-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)-alpha-((5-quinolinyloxy)methyl)-, (S)-. Grades: 98%. CAS No. 154531-78-9. Molecular formula: C31H33N3O2. Mole weight: 479.61.
CP-120509
It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella. Molecular formula: C45H76O17. Mole weight: 889.07.
CP-122721
CP-122721, a phenylpiperidin derivative, has been found to be a NK1 receptor antagonist that could probably be effective as antidepressant and antiemetic agent. The result of Phase II clinical trial for depression of it has not been reported yet since 2003. Synonyms: CP122721; CP 122721; 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-piperidine. Grades: 98%. CAS No. 145742-28-5. Molecular formula: C20H23F3N2O2. Mole weight: 380.40.
CP 135807
CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist. Synonyms: CP135807; CP-135807; 3-(N-Methylpyrrolidin-2-ylmethyl)-5-(3-nitropyrid-2-ylamino)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine. Grades: ≥98% by HPLC. CAS No. 151272-90-1. Molecular formula: C19H21N5O2. Mole weight: 351.40.
CP-135807
A selective 5-HT1D receptor agonist. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine; CP 135807. Grades: Highly Purified. CAS No. 151272-90-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-141938
CP-141938. Group: Biochemicals. Alternative Names: rel-N- [4-Methoxy-3- [ [ [ (2R, 3R) -2-phenyl-3-piperidinyl] amino] methyl] phenyl] -N-methyl-methanesulfonamide. Grades: Highly Purified. CAS No. 182822-62-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H29N3O3S. US Biological Life Sciences.
Worldwide
CP 154526
The hydrochloride salt form of CP-154526, which has been found to be a non-peptide CRF1 receptor antagonist and could exhibit anxiolytic-like activity at some extent. Synonyms: CP 154526; CP154526; CP-154526; N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 257639-98-8. Molecular formula: C23H32N4.HCl. Mole weight: 400.99.
CP 154526 hydrochloride
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K i of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (K i=>10 μM). CP 154526 hydrochloride has anxiolytic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 257639-98-8. Pack Sizes: 5 mg. Product ID: HY-12129.
CP-154526 Hydrochloride
A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. Group: Biochemicals. Alternative Names: N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride. Grades: Highly Purified. CAS No. 257639-98-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-195494
CP-195494, a benzothiazol derivative, was once studied as a leukotriene receptor antagonist. Synonyms: UNII-1D055URF6U; CHEMBL300701; CP195494; CP 195494; CP-195494; (+)-CP-195494; 1D055URF6U; BDBM50070919. Grades: 98%. CAS No. 158103-57-2. Molecular formula: C26H22F4N2O5S2. Mole weight: 582.59.
CP-195543
CP-195543 is a potent and selective leukotriene B4 antagonist developed as an oral treatment for for inflammatory diseases. Synonyms: 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid; 2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid; CP 195543; CP-195543; CP195543. Grades: >98%. CAS No. 204981-48-6. Molecular formula: C24H19F3O4. Mole weight: 428.4.
CP-199330
CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grades: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01.
CP-199330 Sodium
The sodium salt form of CP-199330 which is a chromen derivative and has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330 sodium; CP 199330 sodium; CP199330 sodium; CP-199330 monosodium salt; Methanesulfonamide, N-(3-((6-((7-chloro-2-quinolinyl)methoxy)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-3-yl)methyl)-4-methoxyphenyl)-1,1,1-trifluoro-, monosodium salt, (3R-cis)-; UNII-74573Q728X component FZCWCSNK. Grades: 98%. CAS No. 158102-98-8. Molecular formula: C28H23ClF3N2NaO6S. Mole weight: 630.99.
CP2
CP2 is a cyclic peptide and it is an inhibitor of the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively. Grades: ≥97%. Molecular formula: C92H120N24O26S. Mole weight: 2010.15.
CP21R7
CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34.
CP-220629
CP-220629, a Pyrazolopyridin derivative, has been found to be a Type 4 cyclic nucleotide phosphodiesterase inhibitor that was once studied as an anti-inflammatory as well as antiasthmatic agent. Synonyms: UNII-BAV9N49AFE; CP-220629; CP 220629; CP220629; BAV9N49AFE; SCHEMBL84865; CHEMBL75819; 1-cyclopentyl-3-ethyl-6-(2-methylphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one. Grades: 98%. CAS No. 162141-96-0. Molecular formula: C20H25N3O. Mole weight: 323.44.
CP22185
CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grades: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34.
CP-225917
CP-225917 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. Molecular formula: C31H38O10. Mole weight: 570.63.
CP 226269
CP 226269 is a selective dopamine D4 agonist. Synonyms: CP-226269; CP 226269; CP226269; 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole. Grades: 99%. CAS No. 220941-93-5. Molecular formula: C18H19FN4. Mole weight: 310.37.
CP 24,879 is an inhibitor of arachidonic acid biosynthesis by inhibition of Δ5/Δ6 desaturase. Synonyms: p-(Isopentyloxy)-aniline; 4-(3-methylbutoxy)-benzenamine monohydrochloride. Grades: ≥98%. CAS No. 10141-51-2. Molecular formula: C11H17NO·HCl. Mole weight: 215.8.
CP26
CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-49116.
CP-263114
CP-263114 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. CAS No. 186700-09-4. Molecular formula: C31H36O9. Mole weight: 552.61.
CP-283097
CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorders were discontinued. Uses: Migraine; neurodegenerative disorders. Synonyms: CP-283097; CP283097; CP 283097; UNII-WHL1Z3GN15;;(3R,4S)-Rel-3,4-dihydro-3-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)-2H-1-benzopyran-4,7-diol. Grades: 98%. CAS No. 138047-56-0. Molecular formula: C21H25NO4. Mole weight: 355.43.
Cp2C / CppC
Cp2C is an omnipresent chemical compound extensively employed in the realm of biomedical industry, recognized for its profound efficacy in restraining the proliferation of cancerous cells, primarily manifested in breast and lung malignancies. Synonyms: P1, P2- Di- (cytidine- 5')- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 29789-88-6. Molecular formula: C18H26N6O15P2 (free acid). Mole weight: 628.4 (free acid).
CP2 (Nic)
CP2 (Nic) is an efficacious and discriminating allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR), and exhibits potential utility as a treatment for cognitive deficits linked with Alzheimer's disease. Synonyms: Nicotinamide cytosine dinucleotide, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H27N5O15P2 (free acid). Mole weight: 639.40 (free acid).
Cp2-SO4
Cp2-SO4, a phenylalanine derivative, reverses interleukin 4 induced 1 (IL4I1)-dependent inhibition of T-cell proliferation with Ki of 21.2 μM. Molecular formula: C14H23NO6S. Mole weight: 333.40.
CP 31398 dihydrochloride
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39.
CP-31398 dihydrochloride
CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217195-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18343A.
CP-31398 Dihydrochloride
A styrylquinazoline derivative that acts as a p53 stabilizing agent. It not only restores p53 functions in mutant p53-expressing cells but can also significantly increase the protein level and promote the activity of wild-type p53 in multiple human cancer cell lines, leading to cell cycle arrest or apoptosis. CP-31398 enhances the protein levels of wild-type p53 by blockade of ubiquitination and degradation of p53 without interrupting the physical association between p53 and MDM2 in vivo. Group: Biochemicals. Alternative Names: N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine Dihydrochloride. Grades: Highly Purified. CAS No. 259199-65-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CP 31398 dihydrochloride hydrate
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride, hydrate (1:2:1); CP31398 dihydrochloride hydrate; CP-31398 dihydrochloride hydrate; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride hydrate. Grades: ≥95%. CAS No. 1853109-76-8. Molecular formula: C22H26N4O.2HCl.H2O. Mole weight: 453.41.
CP-31398 Dihydrochloride Hydrate. Group: Biochemicals. Alternative Names: N3-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine Hydrochloride Hydrate. Grades: Highly Purified. CAS No. 1217195-61-3. Pack Sizes: 10mg. Molecular Formula: C22H28Cl2N4O; xH2O, Molecular Weight: 435.39. US Biological Life Sciences.
Worldwide
CP-316311
CP-316311, a pyridine derivative, has been found to be a CRF 1 receptor antagonist and was once studied as an antidepressant agent by Pfizer. IC50: 6.8 nM. Synonyms: CP-316311; CP 316311; CP316311; CP-316,311; CP 316,311; CP316,311; Pyridine, 4-(1-ethylpropoxy)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-. Grades: 98%. CAS No. 175139-41-0. Molecular formula: C21H29NO2. Mole weight: 327.47.
CP 316819
CP 316819. Group: Biochemicals. Grades: Purified. CAS No. 186392-43-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP 316819
CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87.
CP-316819
A novel glycogen phosphorylase inhibitor; potential treatment for glycemic control in type 2 diabetes. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; GPi 819; CP 316 819. Grades: Highly Purified. CAS No. 186392-43-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-320626
CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide;CP-320626; CP320626; CP 320626. Grades: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90.
CP-331684
CP-331684 is a β3-adrenergic receptor agonist used as antidiabetic drug. Synonyms: CP-331684; CP331684; CP 331684; UNII-9EY0MGZ7F8. 2- [4- [2- [ [ (2R) -2- (6-aminopyridin-3-yl) -2-hydroxyethyl] amino] ethoxy] phenyl] acetic acid. Grades: >98%. CAS No. 207922-70-1. Molecular formula: C17H21N3O4. Mole weight: 331.37.
CP-335963
CP-335963. Group: Biochemicals. Alternative Names: 4-Chloro-6, 7-bis (2-methoxyethoxy) quinazoline; 4-Chloro-6, 7-di (2-methoxyethoxy) quinazoline; 6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline; PF-508367. Grades: Highly Purified. CAS No. 183322-18-1. Pack Sizes: 10mg. Molecular Formula: C14H17ClN2O4, Molecular Weight: 312.75. US Biological Life Sciences.
Worldwide
CP 339818 hydrochloride
CP 339818 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 478341-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP 339818 hydrochloride
CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574.
CP 339818 hydrochloride
CP 339818 hydrochloride is the hydrochloride salt form of CP 339818, a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, hydrochloride (1:1); 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, monohydrochloride; Cp 339818 monohydrochloride; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine hydrochloride; 1-Benzyl-N-pentylquinolin-4(1H)-imine hydrochloride; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 478341-55-8. Molecular formula: C21H24N2.HCl. Mole weight: 340.89.
CP 346086
CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grades: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48.
CP 346086 Dihydrate
CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-35587
CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Synonyms: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43.
CP-376395 HCl
CP-376395 HCl is a potent and selective CRF1 receptor antagonist with Ki values of 12 and >10000 nM for CRF1 and CRF2 receptors respectively. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP376395 HCl; CP 376395 HCl; 2-(Mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride;3,6-Dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine hydrochloride. Grades: >98 %. CAS No. 1013933-37-3. Molecular formula: C21H31ClN2O. Mole weight: 362.94.
CP 376395 hydrochloride
CP 376395 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1013933-37-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP-394531
CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grades: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14.
CP-409092
CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grades: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35.
CP 412065
It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Synonyms: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53.
CP 424174
CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99.
CP-432
CP-432 is an EP4 prostaglandin agonist , potential useful for the treatment of glaucoma and ocular hypertension. Uses: An ep4 prostaglandin agonist. Synonyms: CP-432; CP 432; CP432; CP-734432; CP 734432; CP734432. 5-(3-((2S)-2-((3R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxo-1-pyrrolidinyl)propyl)-2-Thiophenecarboxylic acid. Grades: ≥95%. CAS No. 431990-08-8. Molecular formula: C23H26F3NO4S. Mole weight: 469.52.
CP-456773 sodium
CP-456773, also known as MCC950 and CRID3, is a potent, orally bioavailable NLRP3 inflammasome inhibitor and inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production for the treatment of inflammatory diseases. Synonyms: sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide; MCC950; MCC 950; MCC-950; CP-45677; CP45677; CP 45677; CRID-3; CRID3; CRID 3; CP-456773 sodium salt; CP 456773 sodium salt; CP456773 sodium salt; Cytokine release inhibitory drug 3. CAS No. 256373-96-3. Molecular formula: C20H24N2NaO5S. Mole weight: 427.46.
CP-457677
CP-457677, also called as TX006169, is a JNK inhibitor. Synonyms: 2-(4-fluorophenoxy)-N-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]pyridine-3-carboxamide; CP-457677; CP457677; CP 457677; UNII-5A83419M4U. Grades: >98%. CAS No. 214535-77-0. Molecular formula: C22H21FN2O3. Mole weight: 380.41.
CP-457920
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued. Synonyms: N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920. Grades: >98%. CAS No. 220860-50-4. Molecular formula: C18H17N3O3. Mole weight: 323.35.
CP 461
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grades: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91.
CP-461 free base
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grades: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45.
CP 465022
CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grades: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41.
CP-465022
CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663.
CP 465022 hydrochloride
CP 465022 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199655-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grades: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82.
CP-466722
CP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells. Synonyms: CP-466722; CP 466722; CP466722. Grades: >98%. CAS No. 1080622-86-1. Molecular formula: C17H15N7O2. Mole weight: 349.35.
CP-467688
CP-467688 is a microsomal triglyceride transfer protein inhibitor used in atherosclerosis therapy. Synonyms: methyl N-[2-[6-[[2-[4- (trifluoromethyl) phenyl]benzoyl]amino]-3, 4-dihydro-1H-isoquinolin-2-yl]ethyl]carbamate; hydrochloride; 909576-25-6 (CP-467688); CP 467688; CP467688; 208590-81-2 (CP-467688 free base). Grades: >98%. CAS No. 208590-81-2. Molecular formula: C27H27ClF3N3O3. Mole weight: 533.97.