A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CP-870893 is a potent and selective agonist of CD40 and a fully human IgG2 mAb. Synonyms: CP-870,893; CP 870,893; CP870,893; CP870893.
CP8754
CP8754 is a bio-active chemical compound. Synonyms: CP-8754; CP 8754; Carbamic acid, cyclopropyl-, (4aR,5R,6R,7R)-2,4,4a,5,6,7-hexahydro-7-methoxy-3,4a,5-trimethyl-2-oxonaphtho(2,3-b)furan-6-yl ester. Grades: 98%. CAS No. 532435-68-0. Molecular formula: C20H25NO5. Mole weight: 359.42.
CP-91149
Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression. Antitumor agent. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; [R-(R*,S*)]-5-Chloro-N-[3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; CP 91149. Grades: Highly Purified. CAS No. 186392-40-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-91149
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Synonyms: CP 91149; CP91149; 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide. Grades: >98%. CAS No. 186392-40-5. Molecular formula: C21H22ClN3O3. Mole weight: 399.87.
CP-91149
CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186392-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13525.
CP 91243
CP 91243 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. CAS No. 135179-21-4. Molecular formula: C50H84O18. Mole weight: 973.19.
CP 91244
CP 91244 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. Synonyms: Semduramicin, 5-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-, (5(2S,5S,6R))-. CAS No. 135215-73-5. Molecular formula: C51H86O18. Mole weight: 987.21.
CP 93129 dihydrochloride is a potent 5HT 1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 879089-64-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101357A.
CP 93129 dihydrochloride
The hydrochloride salt form of CP 93129, which is a 5HT1B agonist and exhibits activities in decreasing body weight as well as reducing food intake in rats. Synonyms: 5H-Pyrrolo[3,2-b]pyridin-5-one, 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, hydrochloride (1:2); 5H-Pyrrolo[3,2-b]pyridin-5-one, 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, dihydrochloride; CP93129 dihydrochloride; CP-93129 dihydrochloride; 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H,4H,5H-pyrrolo[3,2-b]pyridin-5-one dihydrochloride; 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ol dihydrochloride. Grades: ≥95% by HPLC. CAS No. 879089-64-2. Molecular formula: C12H13N3O.2HCl. Mole weight: 288.18.
CP-93129 Dihydrochloride Hydrate.
CP-93129 Dihydrochloride Hydrate. Group: Biochemicals. Alternative Names: 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrolo[3,2-b]pyridin-5-one Hydrochloride Hydrate. Grades: Highly Purified. CAS No. 879089-64-2. Pack Sizes: 10mg. Molecular Formula: C12H15Cl2N3O, Molecular Weight: 288.17. US Biological Life Sciences.
Worldwide
CP 94253 hydrochloride
The hydrochloride salt form of CP 94253, which is a 5-HT1B agonist and exhibit anticonvulsant activities. Synonyms: CP94253 hydrochloride; CP-94253 hydrochloride; 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride; 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, hydrochloride (1:1); 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, monohydrochloride. Grades: ≥98% by HPLC. CAS No. 845861-39-4. Molecular formula: C15H19N3O.HCl. Mole weight: 293.80.
CP 94253 hydrochloride
CP 94253 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 845861-39-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP94253 hydrochloride
CP94253 hydrochloride is a potent and selective agonist of 5-HT 1B receptor ( K i = 2 nM in a radioligand binding assay).K i values for 5-HT 1A , 5-HT 1D , 5-HT 1C and 5-HT 2 receptors are 89, 49, 860, and 1600 nM respectively [1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845861-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103151.
CP-94707
CP-94707 is a new nonnucleoside reverse transcriptase inhibitor (NNRTI). Uses: Nnrt inhibitor. Synonyms: CP-94707; CP 94707; CP94707; UNII-YGC6408B5O; 3-[[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenyl]methyl]-1,3-benzothiazol-2-one. Grades: ≥98%. CAS No. 343250-05-5. Molecular formula: C21H16N4OS. Mole weight: 372.44.
CP 96345
CP 96345 is an effective and selective non-peptide NK1 receptor antagonist and has been found to show activities in restraining neurogenic inflammation in vivo. Uses: Hypnotics and sedatives. Synonyms: CP-96345; CP 96345; CP96345; (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine. Grades: ≥98% by HPLC. CAS No. 132746-60-2. Molecular formula: C28H32N2O. Mole weight: 412.57.
CP 99433
CP 99433, a fluoroquinolone derivative, has been found to be a Type II DNA topoisomerase inhibitor that could be probably effective as an antibacterial agent. Synonyms: CP 99433; CP99433; CP-99433. 3-Azabicyclo[3.1.0]hexane, 1,8-naphthyridine-3-carboxylic acid deriv; 1,?8-Naphthyridine-3-carboxylic acid, 7-(6-amino-3-azabicyclo[3.1.0]?hex-3-yl)?-1-cyclopropyl-6-fluoro-1,?4-dihydro-4-oxo-, (1α,?5α,?6α)?-. Grades: 98%. CAS No. 147059-71-0. Molecular formula: C17H17FN4O3. Mole weight: 344.34.
CP 99994 dihydrochloride
The hydrochloride salt form of CP 99994, which is a high affinity NK1 antagonist and could attenuate endothelium-dependent contraction induced by substance P. Synonyms: CP 99994 dihydrochloride; CP99994 dihydrochloride; CP-99994 dihydrochloride; (2S,3S)-N-[(2-Methoxyphenyl)methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 145148-39-6. Molecular formula: C19H24N2O.2HCl. Mole weight: 369.33.
CPA inhibitor
CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA). Synonyms: carboxypeptidase inhibitor; Benzenepropanoic acid. alpha.-[[hydroxy(2-phenylacetyl)amino]methyl]-. Grades: >98%. CAS No. 223532-02-3. Molecular formula: C18H19NO4. Mole weight: 313.35.
CPCCOEt
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179067-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101356.
CPCCOEt
CPCCOEt has been found to be a mGluR-1 antagonist. Synonyms: 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester. Grades: ≥99% by HPLC. CAS No. 179067-99-3. Molecular formula: C13H13NO4. Mole weight: 247.25.
A potent, negative allosteric modulator selective for mGlu1 receptors (IC50 = 6.5uM). No effect on other mGlu subtype receptors and ionotropic glutamate receptors at concentrations less than 100uM. Acts by inhibiting an intramolecular interaction between the agonist-bound extracellular domain and the transmembrane domain. Widely used for studies related to peripheral pain and central pain pathways. Group: Biochemicals. Grades: Highly Purified. CAS No. 179067-99-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CP (Chlorinated Paraffin)
Chlorinated paraffin is a complex chemical compound that is used as a flame retardant, plasticizer, and lubricant in a variety of industrial and consumer products. It is a white or pale yellow, waxy solid that has a strong, chlorine-like odor. Uses: CP is typically used in the production of rubber, plastics, paints, and coatings. It is also used as a flame retardant in textiles, as a lubricant in metalworking fluids, and as a plasticizer in PVC and other polymers. Group: Synthetic. Alternative Names: Chlorinated alkanesChlorinated alkenesChlorinated paraffinsPolychlorinated n-alkanesPolychlorinated n-alkenes. Grades: Technical Grade. CAS No. 85535-85-9.
CpCp
Cas No. 3768-14-7.
CpCpp
CpCpp is a compound used in studying a diverse array of malignant neoplasms, intricate neurological impairments and intractable autoimmune maladies. Synonyms: (CMPCPP); Cytidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 101553-55-3. Molecular formula: C10H18N3O13P3 (free acid). Mole weight: 481.18 (free acid).
CPDA
CPDA, a 4-substituted 2-pyridin-2-ylamide, has potential to inhibit SHIP2 which was found to enhance insulin signaling through the Akt pathway in viro and greatly improved abnormal glucose metabolism in diabetic animals. Synonyms: N-[4-[(4-chlorophenyl)methoxy]pyridin-2-yl]-2-(2,6-difluorophenyl)acetamide CPDA CHEMBL2337808 SCHEMBL14156872 AKOS027447209 CS-4991 AK517293 HY-18685 N-[4-(4-Chlorobenzyloxy)-2-pyridyl]-2,6-difluorobenzeneacetamide N-(4-((4-Chlorobenzyl)oxy)pyridin-2-yl). CAS No. 1415834-63-7. Molecular formula: C20H15ClF2N2O2. Mole weight: 388.79.
CPDA
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685.
cPEPCK inhibitor is the first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK). Synonyms: N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide. Grades: 98%. CAS No. 628279-07-2. Molecular formula: C25H26FN5O3. Mole weight: 463.5.
C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 41475-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4858.
C-Peptide 1 (rat)
C-Peptide 1 (rat) specifically binds to G-protein-coupled membrane receptors in the nanomolar concentration range, and subsequently activates Ca2+-dependent intracellular signaling pathways. This leads to a stimulation of the activity of both Na+-K+-ATPase, and endothelial nitric oxide synthase. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. Synonyms: Insulin 1 Precursor (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-prolyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-L-alpha-glutamyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine. Grades: ≥95%. CAS No. 41475-27-8. Molecular formula: C140H228N38O51. Mole weight: 3259.53.
C-Peptide 2 (rat)
C-Peptide 2 (rat), a peptide composed of 31 amino acid residues, can effectively improve glucose utilization in streptozotocin induced diabetic rats. It is a component of proinsulin, and can inhibit glucose-induced insulin secretion. Synonyms: Preproinsulin 2 (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Ala-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-alanyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine; Insulin 2 Precursor (57-87) (rat); Proinsulin 2 (33-63) (rat). Grades: ≥95% by HPLC. CAS No. 41594-08-5. Molecular formula: C135H222N38O49. Mole weight: 3161.43.
C-Peptide, dog
C-Peptide, dog is a component of proinsulin. C-peptide is a marker of insulin secretion in understanding the pathophysiology of type 1 and type 2 diabetes. Synonyms: C-Peptide (dog). Grades: >95% by HPLC. CAS No. 39016-05-2. Molecular formula: C137H225N37O49. Mole weight: 3174.47.
C-Peptide (Hyperproinsulinemia, Insulin Precursor, Proinsulin), Positive Control
C-Peptide (Hyperproinsulinemia, Insulin Precursor, Proinsulin), Positive Control. Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences.
Worldwide
CPF-AM1
CPF-AM1 is a novel insulinotropic peptide from the skin secretion of the clawed frog, Xenopus amieti. Synonyms: caerulein-precursor fragment AM1.
CPF-AM4
The source of CPF-AM4 is the octoploid frog Xenopus amieti (Pipidae). CPF-AM4 has antibacterial activity against Escherichia coli and Staphylococcus aureus. Grades: >98% by HPLC.
CPF-B1
CPF-B1 is produced by Xenopus borealis. The peptide with the greatest potential for development into a therapeutically valuable anti-infective agent was CPF-B1 with MIC=5 microM against E. coli, MIC=5 microM against S. aureus, and MIC=25 microM against Candida albicans, and low hemolytic activity against human erythrocytes (LC(50)>200 microM). Synonyms: GLGSLLGKAFKIGLKTVGKMMGGAPREQ; CPF-B1. Molecular formula: C126H218N36O34S2. Mole weight: 2845.4.
CPF-C1
CPF-C1 is a typical cationic antimicrobial peptide that was originally isolated from the tetraploid frog Xenopus clivii. CPF-C1 has potent antimicrobial activity against both sensitive and multidrug-resistant bacteria.
CPF-L1
CPF-L1 was found in Xenopus lenduensis. It has antibacterial activity.
CPF-L2
CPF-L2 was found in Xenopus lenduensis. It has antibacterial activity.
CPF-P2
CPF-P2 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC= 6 uM). The source of CPF-P2 is skin secretions, Xenopus petersii, Africa. Grades: >95% by HPLC.
CPF-P3
CPF-P3 has antibacterial activity against E. coli (MIC=12.5 uM) and S. aureus (MIC=6 uM). The source of CPF-P3 is skin secretions, Xenopus petersii, Africa. Grades: >98% by HPLC.
CPF-P4
CPF-P4 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC=6 uM). The source of CPF-P4 is skin secretions, Xenopus petersii, Africa. Grades: >96% by HPLC.
CPF-P5
CPF-P5 was found in Xenopus petersii. It has antibacterial activity.
CPF-PG1
CPF-PG1 from X. pygmaeus combined high antimicrobial potency against Staphylococcus aureus (MIC=6 μM) with relatively low hemolytic activity (LC(50)=145 μM).
CPF-SE1
The source of CPF-SE1 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, Africa. It moderately active against E. coli (MIC=40 uM) and highly active against S. aureus MRSA (MIC=2.5 uM).
CPF-SE2
The source of CPF-SE2 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, and Silurana paratropicalis, Africa. It moderately active against E. coli and highly active against S. aureus and MRSA (MIC=2.5 uM).
CPF-St4
CPF-St4 was found in the African clawed frog Silurana tropicalis. It is active against E. coli (MIC 2-4 uM), P. aeruginosa (MIC 4-8 uM), S. aureus (MIC 1 uM), M. luteus (MIC 0.5 uM), and S. cerevisiae (MIC 16 uM). CPF-St4 is also toxic to erythrocytes (HC50 64 uM) and T-lymphocytes (IC50 2 uM).
CPF-St5
CPF-St5 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPF-St6
CPF-St6 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPF-St7
CPF-St7 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPG52364
CPG52364 a small molecule toll-like receptor(TLR) antagonist, which is a type I transmembrane receptors and the central components of the innate immune system. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 is used for the sle therapy. Synonyms: CPG-52364; CPG 52364; CPG52364; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine. Grades: >98%. CAS No. 1093135-60-4. Molecular formula: C27H36N6O3. Mole weight: 492.62.
CPG52364 sulfate
CPG52364 sulfate is the sulfate form of CPG52364, which is a small molecule toll-like receptor(TLR) antagonist. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 sulfate is used for the sle therapy. Synonyms: CPG-52364 sulfate; CPG 52364 sulfate; CPG52364 sulfate; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine sulfate. Grades: >98%. CAS No. 1093135-62-6. Molecular formula: C27H38N6O7S. Mole weight: 590.70.
c(phg-isoDGR-(NMe)k)
c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with IC50 of 2.9 nM. Grades: >98%. CAS No. 1844830-65-4. Molecular formula: C27H41N9O7. Mole weight: 603.67.
C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025.
C-phycocyanin α-cysteine-84 phycocyanobilin lyase
The enzyme, characterized from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the covalent attachment of the phycobilin chromophore phycocyanobilin to cysteine 84 of the α subunit of the phycobiliprotein C-phycocyanin. Group: Enzymes. Synonyms: cpcE (gene name); cpcF (gene name). Enzyme Commission Number: EC 4.4.1.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5335; C-phycocyanin α-cysteine-84 phycocyanobilin lyase; EC 4.4.1.32; cpcE (gene name); cpcF (gene name). Cat No: EXWM-5335.
C-phycocyanin from aphanoteca*halophytica
Heterocyclic Organic Compound. CAS No. 11016-15-2. Catalog: ACM11016152.
CPI-1189
CPI-1189 is an inhibitor of TNF-α release with the potential use to treat sciatica and postherpetic neuralgia. Synonyms: 4-Acetamido-N-tert-butylbenzamide; CPI-1189; REN-1189; REN-1654; CPI1189; REN1189; REN1654; CPI 1189; REN 1189; REN 1654. CAS No. 183619-38-7. Molecular formula: C13H18N2O2. Mole weight: 234.299.
CPI-169
CPI-169 is a novel and potent EZH2 inhibitor, it decreases cellular levels of H3K27me3 and triggers cell cycle arrest and apoptosis in a variety of cell lines. Synonyms: CPI-169; CPI 169; CPI169. Grades: >98%. CAS No. 1450655-76-1. Molecular formula: C27H36N4O5S. Mole weight: 528.66.
CPI203
CPI203, also known as TEN010, JQ-2; RO6870810 and RG6146, is a potent and orally active BET bromodomain inhibitor. CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors. CPI203 ownregulates Myc expression, causes G1 cell cycle arrest and attenuates cell proliferation in human pancreatic neuroendocrine tumors. CPI203 arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Group: Inhibitors. Alternative Names: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.9. Appearance: Solid powder. Purity: >98%. IUPACName: (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide. Canonical SMILES: O=C (N)C[C@H]1C2=NN=C (C)N2C3=C (C (C)=C (C)S3)C (C4=CC=C (Cl)C=C4)=N1. Catalog: ACM1446144042.
CPI 203
CPI 203. Group: Biochemicals. Grades: Purified. CAS No. 1446144-04-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CPI-203
CPI-203 is a BET bromodomain inhibitor. It inhibits BRD4 in vitro and in cells, and causes G1 cell cycle arrest. It also arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Synonyms: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. Grades: >98%. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.90.
CPI-268456
CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 and inhibits LPS-induced IL-6 secretion in THP-1 cells. Synonyms: 2-[(4S)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepin-4-yl]acetamide. Grades: ≥98%. CAS No. 1380087-86-4. Molecular formula: C20H15Cl2N3O2. Mole weight: 400.3.
CPI-360
CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases. Synonyms: CPI-360; CPI360; CPI 360. Grades: 98%. CAS No. 1802175-06-9. Molecular formula: C25H31N3O4. Mole weight: 437.53.
CPI 4203
CPI 4203 is a selective inhibitor of KDM5 demethylases structurally related to CPI 455. Synonyms: CPI-4203; CPI 4203; CPI4203; 6-ethyl-7-oxo-5-(o-tolyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grades: 99%. CAS No. 1628214-07-2. Molecular formula: C16H14N4O. Mole weight: 278.31.
CPI-444
CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications. Synonyms: (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; CPI-444; CPI 444; CPI444; V81444; V-81444; V 81444. CAS No. 1202402-40-1. Molecular formula: C20H21N7O3. Mole weight: 407.17.
CPI 455
CPI 455 is a selective inhibitor of KDM5 demethylases (IC50 value 10 nM for inhibition of full length KDM5A) that specifically alters H3K4 methylation (H3K4me3) in vitro and reduces survival of drug-tolerant cancer cells. Uses: Antitumor agent for drug-tolerant cancer. Synonyms: CPI-455; CPI-455; CPI-455; 6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grades: 99%. CAS No. 1628208-23-0. Molecular formula: C16H14N4O. Mole weight: 278.31.