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| Product | Description | |
|---|---|---|
| Iturin A | Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322. |  |
| ITX3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ITX3 | ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs. Synonyms: ITX 3; ITX-3. Grades: >98%. CAS No. 347323-96-0. Molecular formula: C22H17N3OS. Mole weight: 371.45. |  |
| ITX 3 | ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ITX-5061 | ITX-5061 is a scavenger receptor B1 antagonist. Preclinical studies show that ITX-5061 is a selective inhibitor of HCV entry into hepatocytes. It can prevent virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA were on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide;1252679-52-9 (HCl salt). Grades: 98%. CAS No. 848144-15-0. Molecular formula: C30H37N3O7S. Mole weight: 583.70. | |
| ITX-5061 HCl | This active molecular is a scavenger receptor B1 antagonist under the development by iTherX Pharmaceuticals for the treatment of Hepatitis C. ITX-5061 shows a special mechanism of action that prevents the hepatitis C virus from entering liver cells. Preclinical studies have shown that ITX-5061 can prevent virus binding/fusion and cell to cell spread. In Jan 2015, Phase-II clinical trials in Hepatitis C in USA was on-going. Uses: Hepatitis c. Synonyms: ITX-5061; ITX 5061; ITX5061; UNII-J4RA8K2Q2A; J4RA8K2Q2A;CHEMBL3402567;N-[5-tert-butyl-3-(methanesulfonamido)-2-methoxyphenyl]-2-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-2-oxoacetamide;hydrochloride;848144-15-0 (free base). Grades: 98%. CAS No. 1252679-52-9. Molecular formula: C30H38ClN3O7S. Mole weight: 620.16. | |
| IU1 | IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IU1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IU1 | IU1 is a cell-permeable, reversible and selective proteasome inhibitor of human USP14 with IC50 of 4.7 μ M, 25-fold selective to IsoT. Synonyms: IU 1; IU-1; 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(pyrrolidin-1-yl)ethan-1-one. Grades: >98%. CAS No. 314245-33-5. Molecular formula: C18H21FN2O. Mole weight: 300.37. | |
| IU1 | IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817. | |
| IU1-47 | IU1-47 is a potent and selective inhibitor of the proteasomal deubiquitinating enzyme USP14 (IC50 = 60 nM). IU1-47 has been shown to enhance protein degradation rate in cells using as a reporter the microtubule-associated protein tau. Synonyms: 1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone. Grades: ≥98% by HPLC. CAS No. 670270-31-2. Molecular formula: C19H23ClN2O. Mole weight: 330.85. | |
| IUN78876 | IUN78876, also known as 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one is a chemical reagent for research use. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IUN78876; IUN-78876; IUN 78876. Product Category: Others. Appearance: Solid powder. CAS No. 1638178-87-6. Molecular formula: C23H22F2N4O. Mole weight: 408.45. Purity: >98%. IUPACName: 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one. Canonical SMILES: O=C1N(CC2=CC=C(F)C=C2F)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4. Product ID: ACM1638178876. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ivabradine | Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155974-00-8. Pack Sizes: 1 mg. Product ID: HY-B0162. | |
| Ivabradine-d3 Hydrochloride | Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivabradine hydrochloride | Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148849-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0162A. | |
| Ivabradine hydrochloride | 3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride. angina therapeutic. CAS No. 148849-67-6. Product ID: 2-08377. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. |  |
| Ivabradine hydrochloride | 3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride. angina therapeutic. CAS No. 148849-67-6. Product ID: 2-08361. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. | |
| Ivabradine hydrochloride | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-100mg. Molecular Weight 505.05. See USA prepack pricing. |  |
| Ivabradine hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-1g. Molecular Weight 505.05. See USA prepack pricing. | |
| Ivabradine Hydrochloride | Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ivabradine Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. | |
| Ivabradine Impurity 1 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: [2-(2-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propylamino}-ethyl)-4,5-dimethoxy-phenyl]-acetic acid. Grades: 95%. CAS No. 1462470-54-7. Molecular formula: C27H38N2O6. Mole weight: 486.60. | |
| Ivabradine Impurity 10 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: N-Propyl-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one; 7,8-dimethoxy-3-propyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one. Grades: > 95%. Molecular formula: C15H21NO3. Mole weight: 263.33. | |
| Ivabradine Impurity 11 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: (7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. Grades: 95%. CAS No. 1132667-04-9. Molecular formula: C12H17NO2. Mole weight: 207.27. | |
| Ivabradine Impurity 12 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 7,8-Dimethoxy-3-(3-methylamino-propyl)-1,3,4,5-tetrahydro-benzo[d]azepin-2-one HCl. Grades: 95%. CAS No. 85175-52-6. Molecular formula: C16H25N2O3Cl. Mole weight: 328.83. | |
| Ivabradine Impurity 13 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ylmethyl)-methyl-amino]-propyl}-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one. Grades: 95%. Molecular formula: C27H36N2O6. Mole weight: 484.58. | |
| Ivabradine Impurity 14 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: Hydroxy Ivabradine; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-5-hydroxy-7,8-dimethoxy-2H-3-benzazepin-2-one. Grades: > 95%. CAS No. 2253977-80-7. Molecular formula: C27H36N2O6. Mole weight: 484.58. | |
| Ivabradine Impurity 15 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-4,5-dihydro-7,8-dimethoxy-1H-3-benzazepine-1,2(3H)-dione; 2-Oxo-ivabradine Hydrochloride. Grades: 95%. CAS No. 1616710-50-9. Molecular formula: C27H35ClN2O6. Mole weight: 519.03. | |
| Ivabradine Impurity 16 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-[(3-hydroxy-4-methoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one; 3-Hydroxy Ivabradine; (S)-3-(3-(((3-Hydroxy-4-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one; 1,3,4,5-Tetrahydro-3-[3-[[[(7S)-3-hydroxy-4-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-7,8-dimethoxy-2H-3-Benzazepin-2-one. Grades: 95%. CAS No. 304464-98-0. Molecular formula: C26H34N2O5. Mole weight: 454.56. | |
| Ivabradine Impurity 17 | Cas No. 866783-13-3. | |
| Ivabradine Impurity 18 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane; 1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine; 3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. Grades: 95%. CAS No. 73344-75-9. Molecular formula: C11H15NO2. Mole weight: 193.24. | |
| Ivabradine Impurity 19 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: N-(2,2-Dimethoxyethyl)-3,4-dimethoxybenzeneacetamide; N-(2,2-Dimethoxy-ethyl)-2-(3,4-dimethoxy-phenyl)-acetamide. Grades: 95%. CAS No. 73954-34-4. Molecular formula: C14H21NO5. Mole weight: 283.32. | |
| Ivabradine Impurity 2 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]oct-7-ylmethyl)-methyl-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one. Grades: > 95%. Molecular formula: C27H42N2O5. Mole weight: 474.63. | |
| Ivabradine Impurity 20 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Molecular formula: C27H35N2O6Cl. Mole weight: 519.03. | |
| Ivabradine Impurity 21 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Grades: 95%. CAS No. 304465-03-0. Molecular formula: C26H34N2O5. Mole weight: 454.56. | |
| Ivabradine Impurity 22 | Cas No. 73942-87-7. | |
| Ivabradine Impurity 23 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Molecular formula: C15H18INO3. Mole weight: 387.21. | |
| Ivabradine Impurity 24 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Molecular formula: C14H19NO3. Mole weight: 249.30. | |
| Ivabradine Impurity 25 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: (S)-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine; (1S)-4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane. Grades: 95%. CAS No. 869856-07-5. Molecular formula: C11H15NO2. Mole weight: 193.24. | |
| Ivabradine Impurity 26 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Grades: 95%. Molecular formula: C13H19NO2. Mole weight: 221.30. | |
| Ivabradine Impurity 27 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Grades: 95%. Molecular formula: C27H38Cl2N2O5. Mole weight: 541.51. | |
| Ivabradine Impurity 28 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Molecular formula: C27H37ClN2O5. Mole weight: 505.04. | |
| Ivabradine Impurity 29 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-Bromopropyl)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one. Grades: 95%. CAS No. 1428869-91-3. Molecular formula: C15H18BrNO3. Mole weight: 340.21. | |
| Ivabradine Impurity 3 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-{3-[(3,4-Dimethoxy-bicyclo[4.2.0]oct-7-ylmethyl)-methyl-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one. Grades: > 95%. Molecular formula: C27H42N2O5. Mole weight: 474.63. | |
| Ivabradine Impurity 4 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-{[2-(3,4-Dimethoxy-phenyl)-propyl]-methyl-amino}-propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one HCl; 3- (3-{[2- (3, 4-dimethoxyphenyl)propyl] (methyl)amino}propyl)-7, 8-dimethoxy-2, 3, 4, 5-tetrahydro-1H-3-benzazepin-2-one hydrochloride; N-(Demethyl)di-ithabradine HCl Impurity. Grades: 95%. Molecular formula: C27H38N2O5. Mole weight: 470.60. | |
| Ivabradine Impurity 5 | Cas No. 85175-59-3. | |
| Ivabradine Impurity 6 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-{[3-Chloro-2-(3,4-dimethoxy-phenyl)-propyl]-methyl-amino}-propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one. Grades: 95%. Molecular formula: C27H38Cl2N2O5. Mole weight: 541.51. | |
| Ivabradine Impurity 7 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3,3'-(Propane-1,3-diyl)bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one); Ivabradine Impurity VI. Grades: 95%. Molecular formula: C27H34N2O6. Mole weight: 482.57. | |
| Ivabradine Impurity 8 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one. Grades: 95%. CAS No. 85175-65-1. Molecular formula: C15H20ClNO3. Mole weight: 297.78. | |
| Ivabradine Impurity 9 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-(7,8-dimethoxy-2-oxo-2,3-dihydro-1H-3-benzazepin-3-yl)propyl]-7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one; 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one. Grades: > 95%. Molecular formula: C27H30N2O6. Mole weight: 478.54. | |
| Ivabradine N-Oxide | a derivative of Ivabradine. Synonyms: 3-(7,8-dimethoxy-2-oxo-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide; 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methyloxidoamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy. Grades: > 95%. CAS No. 2511244-97-4. Molecular formula: C27H36N2O6. Mole weight: 484.60. | |
| Ivabradine R-Isomer HCl | The enantiomer of Ivabradine Hydrochloride. Ivabradine is a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Synonyms: ent-Ivabradine Hydrochloride; 3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride. Grades: > 95%. CAS No. 148849-68-7. Molecular formula: C27H37ClN2O5. Mole weight: 505.06. | |
| Ivacaftor | Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. Uses: Chloride channel agonists. Synonyms: N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770. Grades: 98%. CAS No. 873054-44-5. Molecular formula: C24H28N2O3. Mole weight: 392.49. | |
| Ivacaftor | Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences. | Worldwide |
| Ivacaftor | Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017. | |
| Ivacaftor | N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide. CAS No. 873054-44-5. Product ID: 8-05083. Molecular formula: C24H28N2O3. Mole weight: 392.49. Properties: cystic fibrosis therapeutic, selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively. MFCD No. MFCD17171361. | |
| Ivacaftor Acyl-Glucuronide | Ivacaftor Acyl-Glucuronide is an impurity of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O10. Mole weight: 582.60. | |
| Ivacaftor Benzenesulfonate | Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Synonyms: N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide Benzenesulfonate;N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Benzenesulfonate; VX-770; VX 770; VX770. Grades: 98%. CAS No. 1134822-09-5. Molecular formula: C30H34N2O6S. Mole weight: 550.66. | |
| Ivacaftor Carboxylic Acid | Ivacaftor Carboxylic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethyl-, 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid, 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethylbenzeneacetic acid, Ivacaftor carboxylic acid, Ivacaftor impurity 1. CAS No. 1246213-24-0. IUPAC Name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. Molecular formula: C24H26N2O5. Mole weight: 422.47. Catalog: APS1246213240. SMILES: CC(C)(C)c1cc(c(O)cc1NC(=O)C2=CNc3ccccc3C2=O)C(C)(C)C(=O)O. Format: Neat. | |
| Ivacaftor Carboxylic Acid Lactone | Ivacaftor Carboxylic Acid Lactone is related to Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: N-[5-(1,1-Dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; N-(5-(tert-Butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Grades: ≥95%. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.46. | |
| Ivacaftor Carboxylic Acid N-Glucuronide | Ivacaftor Carboxylic Acid N-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Grades: 95%. Molecular formula: C30H34N2O11. Mole weight: 598.60. | |
| Ivacaftor Carboxylic Acid O-Glucuronide | Ivacaftor Carboxylic Acid O-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O11. Mole weight: 598.60. | |
| Ivacaftor-d18 | Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences. | Worldwide |
| Ivacaftor-d19 | Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VX-770-d19. CAS No. 1413431-22-7. Pack Sizes: 5 mg; 1 mg. Product ID: HY-13017S1. | |
| Ivacaftor hydrate | Ivacaftor hydrate is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. Synonyms: VX-770 hydrate; N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrate; 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, hydrate (1:1); N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide hydrate (1:1); Kalydeco hydrate. Grades: >98%. CAS No. 1134822-07-3. Molecular formula: C24H30N2O4. Mole weight: 410.51. | |
| Ivacaftor impurities5 | Ivacaftor impurities5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.48. Catalog: APB1246213240. | |
| Ivacaftor impurities6 | Ivacaftor impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB1246213239. | |
| Ivacaftor impurities7 | Ivacaftor impurities7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB1246213411. | |
| Ivacaftor Impurity 1 | an impurity of Ivacaftor. Synonyms: Ivacaftor Carboxylic Acid; 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethylbenzeneacetic Acid. Grades: > 95%. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.49. | |
| Ivacaftor Impurity 2 | an impurity of Ivacaftor. Synonyms: Hydroxymethyl Ivacaftor; N-[2-(1,1-Dimethylethyl)-5-hydroxy-4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide. Grades: > 95%. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.50. | |
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