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An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-[3-(7,8-dimethoxy-2-oxo-2,3-dihydro-1H-3-benzazepin-3-yl)propyl]-7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one; 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one. Grades: > 95%. Molecular formula: C27H30N2O6. Mole weight: 478.54.
Ivabradine N-Oxide
a derivative of Ivabradine. Synonyms: 3-(7,8-dimethoxy-2-oxo-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide; 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methyloxidoamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy. Grades: > 95%. CAS No. 2511244-97-4. Molecular formula: C27H36N2O6. Mole weight: 484.60.
Ivabradine R-Isomer HCl
The enantiomer of Ivabradine Hydrochloride. Ivabradine is a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Synonyms: ent-Ivabradine Hydrochloride; 3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride. Grades: > 95%. CAS No. 148849-68-7. Molecular formula: C27H37ClN2O5. Mole weight: 505.06.
Ivacaftor
Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017.
Ivacaftor
Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. Uses: Chloride channel agonists. Synonyms: N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770. Grades: 98%. CAS No. 873054-44-5. Molecular formula: C24H28N2O3. Mole weight: 392.49.
Ivacaftor
Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences.
Worldwide
Ivacaftor
N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide. CAS No. 873054-44-5. Product ID: 8-05083. Molecular formula: C24H28N2O3. Mole weight: 392.49. Properties: cystic fibrosis therapeutic, selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively. MFCD No. MFCD17171361.
Ivacaftor Acyl-Glucuronide
Ivacaftor Acyl-Glucuronide is an impurity of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O10. Mole weight: 582.60.
Ivacaftor Benzenesulfonate
Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Synonyms: N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide Benzenesulfonate;N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Benzenesulfonate; VX-770; VX 770; VX770. Grades: 98%. CAS No. 1134822-09-5. Molecular formula: C30H34N2O6S. Mole weight: 550.66.
Ivacaftor Carboxylic Acid
Ivacaftor Carboxylic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethyl-, 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid, 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-?,?-dimethylbenzeneacetic acid, Ivacaftor carboxylic acid, Ivacaftor impurity 1. CAS No. 1246213-24-0. IUPAC Name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. Molecular formula: C24H26N2O5. Mole weight: 422.47. Catalog: APS1246213240. SMILES: CC(C)(C)c1cc(c(O)cc1NC(=O)C2=CNc3ccccc3C2=O)C(C)(C)C(=O)O. Format: Neat.
Ivacaftor Carboxylic Acid Lactone
Ivacaftor Carboxylic Acid Lactone is related to Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: N-[5-(1,1-Dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; N-(5-(tert-Butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Grades: ≥95%. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.46.
Ivacaftor Carboxylic Acid N-Glucuronide
Ivacaftor Carboxylic Acid N-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Grades: 95%. Molecular formula: C30H34N2O11. Mole weight: 598.60.
Ivacaftor Carboxylic Acid O-Glucuronide
Ivacaftor Carboxylic Acid O-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O11. Mole weight: 598.60.
Ivacaftor-d18
Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences.
Worldwide
Ivacaftor-d19
Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VX-770-d19. CAS No. 1413431-22-7. Pack Sizes: 5 mg; 1 mg. Product ID: HY-13017S1.
Ivacaftor hydrate
Ivacaftor hydrate is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. Synonyms: VX-770 hydrate; N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrate; 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, hydrate (1:1); N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide hydrate (1:1); Kalydeco hydrate. Grades: >98%. CAS No. 1134822-07-3. Molecular formula: C24H30N2O4. Mole weight: 410.51.
Ivacaftor impurities5
Ivacaftor impurities5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.48. Catalog: APB1246213240.
Ivacaftor impurities6
Ivacaftor impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.5. Catalog: APB1246213239.
Ivacaftor impurities7
Ivacaftor impurities7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB1246213411.
Ivacaftor Impurity 1
an impurity of Ivacaftor. Synonyms: Ivacaftor Carboxylic Acid; 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethylbenzeneacetic Acid. Grades: > 95%. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.49.
Ivacaftor Impurity 2
an impurity of Ivacaftor. Synonyms: Hydroxymethyl Ivacaftor; N-[2-(1,1-Dimethylethyl)-5-hydroxy-4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide. Grades: > 95%. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.50.
Ivacaftor N-Glucuronide
Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences.
Worldwide
Ivacaftor-N-Glucuronide
Ivacaftor-N-Glucuronide is a metabolite of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Ivacaftor N-β-D-Glucuronide. Grades: 98%. Molecular formula: C30H36N2O9. Mole weight: 568.61.
Ivacaftor-O-Glucuronide
Ivacaftor-O-Glucuronide is a metabolite of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Ivacaftor O-β-D-Glucuronide. Grades: 98%. Molecular formula: C30H36N2O9. Mole weight: 568.61.
Ivachtin
Ivachtin is a potent and non-competitive caspase-3 inhibitor. It exhibits 10-100 fold selectivity over other caspases and more potent anti-apoptotic activity than Z-VAD-FMK. Synonyms: Caspase-3 Inhibitor VII; 2-(4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl)ethyl acetate. Grades: 99%. CAS No. 745046-84-8. Molecular formula: C20H21N3O7S. Mole weight: 447.46.
Ivarmacitinib
Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2 , 77-fold for JAK3 , 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR0302. CAS No. 1445987-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112724.
Ivebradine impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1086026-31-4. Molecular formula: C27H34N2O5. Mole weight: 466.58. Catalog: APB1086026314.
Ivermectin
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grades: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X 4 and the α7 neuronal nicotinic acetylcholine receptor ( nAChRs ). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import [1] [2] [3] [4]. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MK-933; CD-5024; K-237. CAS No. 70288-86-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-15310.
Ivermectin
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H74O14. CAS No. 70288-86-7. Prepack ID 21022571-1g. Molecular Weight 875.09. See USA prepack pricing.
Ivermectin 2-epimer
an epimer of Ivermectin. Synonyms: 2-epi-Ivermectin B1a. Grades: > 95%. Molecular formula: C48H74O14. Mole weight: 875.12.
Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
Worldwide
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) [1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71827-03-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-126937.
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. Purity: 0.85. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-1. Alfa Chemistry ISO 9001:2015 Certified.
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Dihydroavermectin B1a; Ivermectin; 22,23-Dihydroavermectin B1a; 5-O-Demethyl-22,23-dihydro-avermectin A1a; Ivermectin Impurity I. Grades: >95% by HPLC. CAS No. 70161-11-4. Molecular formula: C48H74O14. Mole weight: 875.12.
Ivermectin B1a-D2
Ivermectin B1a-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. Appearance: Pale Beige to Brown Solid. CAS No. 71827-03-7 (Unlabelled). Molecular formula: C48H72D2O14. Mole weight: 877.11. Purity: 0.94. IUPACName: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Product ID: ACM71827037-2. Alfa Chemistry ISO 9001:2015 Certified.
Ivermectin B1a-D2
Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences.
Worldwide
Ivermectin B1 Aglycon
Ivermectin B1 Aglycon. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-, (6R,13S,25R)-,(6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B, 22,23-Dihydroavermectin B1a Aglycon, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B Deriv., Ivermectin Imp. G (EP), Ivermectin Aglycone, [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. CAS No. 73162-95-5. Pack Sizes: 1MG. Molecular formula: C34H50O8. Mole weight: 586.76. Catalog: APS73162955. SMILES: CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(/C)\[C@@H](O)[C@@H](C)\C=C\C=C\4/CO[C@@H]5[C@H](O)C(=C[C@@H](C(=O)O3)[C@]45O)C)O2. Format: Neat. Shipping: Room Temperature.
Ivermectin B1 Aglycon
Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences.
Worldwide
Ivermectin B1 aglycone
A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grades: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76.
Ivermectin B1b
Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences.
Worldwide
Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Dihydroavermectin B1b; 22,23-Dihydroavermectin B1b; Avermectin H2B1b. Grades: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C47H72O14. Mole weight: 861.06.
Ivermectin B1 monosaccharide
Ivermectin B1 monosaccharide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. Appearance: White to off-white solid. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Purity: 0.98. IUPACName: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Product ID: ACM71837279. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin B1a monosaccharide.
Ivermectin B1 Monosaccharide
Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences.
Worldwide
Ivermectin-d2
Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin-D2
Ivermectin-D2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22,23-Dihydroavermectin B1-d2. Appearance: White to Pale Beige Solid. CAS No. 70288-86-7. Molecular formula: C48H72D2O14. Mole weight: 877.12. Purity: 0.97. IUPACName: (1R,4R,5'S,6R,6'S,8S,10Z,12S,13S,14Z,20R,21S,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2S,4S,5R,6S)-5-[(2R,4S,5R,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@H]1[C@H](CC[C@@]2(O1)C[C@H]3C[C@@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@@H]5O)C)C(=O)O3)O)C)O[C@@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@@H]7C[C@@H]([C@@H]([C@@H](O7)C)O)OC)OC)/C)C. Product ID: ACM70288867. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ivermectin during the COVID-19 pandemic.
Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin impurity 10
Ivermectin impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1135339-49-9. Molecular formula: C48H74O14. Mole weight: 875.11. Catalog: APB1135339499.
Ivermectin impurity 5
Ivermectin impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.09. Catalog: APB102190556.
Ivermectin Impurity D
an impurity of Ivermectin. Synonyms: 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10.
Ivermectin Impurity G
an impurity of Ivermectin. Synonyms: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. Grades: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77.
Ivermectin Impurity H
an impurity of Ivermectin. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94.
Ivermectin Impurity K
an impurity of Ivermectin. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13.
Ivermectin monosaccharide
A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grades: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92.
Ivermectin monosaccharide is a semi-synthetic produced by the selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 monosaccharide, Ivermectin B1 monosaccharide. Grades: Highly Purified. CAS No. 123997-64-8. Pack Sizes: 1mg. US Biological Life Sciences.
Ivonescimab (AK112) is a PD-1 / VEGF Bispecific Antibody. Ivonescimab can be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK112. CAS No. 2428381-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99675.
Ivory nut mannan
Cas No. 37251-47-1.
Ivosidenib
Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme , it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-120. CAS No. 1448347-49-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18767.
Ivosidenib
Ivosidenib is an oral inhibitor that specifically inhibits a mutated form of IDH1 in the cytoplasm, which blocks the proliferation of tumor cells expressing IDH1. Synonyms: AG-120; AG 120; AG120; (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide. CAS No. 1448347-49-6. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.968.
Ivospemin
Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBP-101. CAS No. 748119-79-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132822.
Ivospemin
Ivospemin is a spermine analogue and an antineoplastic drug. Synonyms: (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol; NSC793107; NSC-793107; 3,8,13,18-Tetraazaeicosane-6,15-diol, (6S,15S)-. CAS No. 748119-79-1. Molecular formula: C16H38N4O2. Mole weight: 318.50.
Ivuxolimab
Ivuxolimab is a humanized agonistic IgG2 monoclonal antibody. Ivuxolimab selectively binds to OX40, resulting in proliferation of memory and effector T lymphocytes. Synonyms: PF-04518600; PF 04518600; PF04518600. CAS No. 2128729-41-7.
Ivuxolimab
Ivuxolimab is a fully human IgG2 agonist targeting OX40 (CD134), which selectively binds to the OX40 receptor on the surface of activated CD4+ and CD8+ T cells without inducing antibody-dependent cytotoxicity. Ivuxolimab can promote T cell proliferation, survival and cytokine (such as IFN-?, IL-2) secretion, inhibit regulatory T cell function, and enhance anti-tumor immune response. Ivuxolimab can be used in the study of melanoma, hepatocellular carcinoma, head and neck squamous cell carcinoma, etc[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2128729-41-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99159.
Ivy extract is prepared from leaf and stem of araliaceae family plant Hedera nepalensis var. sinensis (tobl.) rehd. Ivy extract is a product that widely used in medicine and cosmetics. Ivy extract has the function of moisturizing skin, and reducing wrinkles on face. Group: Others. Mole weight: 472.7. Ivy Extract; Hedera Nepalensis Var. Sinensis (Tobl.) Rehd. Cat No: EXTC-059.