A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ispinesib is a specific inhibitor of kinesin spindle protein (KSP) , with a K i app of 1.7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-715992. CAS No. 336113-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50759.
Ispronicline
Ispronicline, also known as AZD3480; TC 1734; TC-0173, and RJR 1734, is a alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties. Ispronicline is potentially useful for the treatment of attention-deficit/hyperactivity disorder in adults. Group: Agonists. Alternative Names: Ispronicline; AZD3480; AZD-3480; AZD 3480; TC 1734; TC-01734; TC1734; TC01734; TC 1734; TC 01734; RJR 1734; RJR-1734; RJR1734. CAS No. 252870-53-4. Molecular formula: C14H22N2O. Mole weight: 234.34. Appearance: Oily liquid. Purity: >98%. IUPACName: (S,E)-5-(5-isopropoxypyridin-3-yl)-N-methylpent-4-en-2-amine. Canonical SMILES: C[C@H](NC)C/C=C/C1=CC(OC(C)C)=CN=C1. Catalog: ACM252870534.
Isracidin
Isracidin is an antibacterial peptide isolated from Bos taurus. Synonyms: H-Arg-Pro-Lys-His-Pro-Ile-Lys-His-Gln-Gly-Leu-Pro-Gln-Glu-Val-Leu-Asn-Glu-Asn-Leu-Leu-Arg-Phe-OH. Grades: 97.9%. Molecular formula: C125H203N39O32. Mole weight: 2764.2.
Isradipine
Isradipine. Group: Biochemicals. Grades: Purified. CAS No. 75695-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Isradipine
Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. Synonyms: DynaCirc; Prescal; Lomir; PN-200-110; PN-205-033; PN-205-034; 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester. Grades: >98%. CAS No. 75695-93-1. Molecular formula: C19H21N3O5. Mole weight: 371.39.
Isradipine
Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PN 200-110. CAS No. 75695-93-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0233.
Heterocyclic Organic Compound. CAS No. 117279-73-9. Catalog: ACM117279739.
ISRIB
ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: 2- (4-chlorophenoxy) -N-[4-[[2- (4-chlorophenoxy) acetyl]amino]cyclohexyl]acetamide 2- (4-chlorophenoxy) -N- (4- (2- (4-chlorophenoxy) acetamido) cyclohexyl) acetamide ISRIB compound trans-ISRIB. CAS No. 1597403-47-8. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34.
ISRIB
ISRIB is a brain-penetrant inhibitor of integrated stress response (ISR). Persistent activation of the ISR has been linked to the development of several neurological disorders as ISR represses translation through inhibiting eIF2B. ISRIB inhibits the ISR by promoting the nucleotide exchange activity of eIF2B and recovering the translation, and thus can be used for neurological disorders research [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 548470-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12495A.
ISRIB (mix-Isomer)
ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: Acetamide, N,?N'-1,?4-cyclohexanediylbis[2?-(4-chlorophenoxy)?- ISRIB compound. CAS No. 548470-11-7. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34.
ISS610
ISS610 is a Signal transducer and activator of transcription 3 (STAT3) inhibitor. Reported has shown that aberrant activation of oncogenic signal transducer and activator of STAT3 protein signaling pathways is implicated in human cancers. Uses: Cancer. Synonyms: ((S)-2-(4-cyanobenzamido)-3-(4-(phosphonooxy)phenyl)propanoyl)-L-leucine. Grades: 98%. CAS No. 725233-55-6. Molecular formula: C23H26N3O8P. Mole weight: 503.45.
Istamycin A
Istamycin A is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: Sannamycin A; Antibiotic KA 7038I; L-chiro-Inositol, 4-amino-1-((aminoacetyl)methylamino)-3-O-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-1,4,5-trideoxy-6-O-methyl-. CAS No. 72503-79-8. Molecular formula: C17H35N5O5. Mole weight: 389.49.
Istamycin B
Istamycin B is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: L-chiro-Inositol, 4-amino-1-(2-amino-N-methylacetamido)-3-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-beta-D-lyxo-hexopyranosyl)-6-O-methyl-1,4,5-trideoxy-. CAS No. 72523-64-9. Molecular formula: C17H35N5O5. Mole weight: 389.49.
Istaroxime
Istaroxime, also called as PST 2744, is an inhibitor of sodium-potassium ATPase that exhibits the unique property of increasing SERCA2a activity. This has been demonstrated in sarcoplasmic reticulum vesicles from normal guinea pigs, where istaroxime incre. Synonyms: PST-2744; PST 2744; PST2744; Istaroxime; (3E,5S,8R,9S,10R,13S,14S)-3-(2-aminoethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochlorideIstaroxi. CAS No. 203737-93-3. Molecular formula: C21H32N2O3. Mole weight: 360.49.
Istaroxime hydrochloride
Istaroxime is a adenosine triphosphatase inhibitor, inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Uses: Inhibitor of na+/k+ atpase. Synonyms: PST-2744 HCl; PST 2744 HCl; PST2744 HCl(3E,5α)-3-[(2-Aminoethoxy)imino]androstane-6,17-dione hydrochloride. Grades: ≥95%. CAS No. 374559-48-5. Molecular formula: C21H33ClN2O3. Mole weight: 396.95.
Istaroxime hydrochloride
Istaroxime hydrochloride is a Na + /K + -ATPase inhibitor ( IC 50 =0.11 μM) and a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ( SERCA 2 ) activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PST2744 hydrochloride. CAS No. 374559-48-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15718A.
Istradefyline
Istradefyline. Group: Biochemicals. Alternative Names: (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,; 8-[ (1E) -2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-purine-2, 6-dione. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H24N4O4. US Biological Life Sciences.
Worldwide
Istradefylline
Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist (Ki=2.2 nM). Uses: Adenosine a2 receptor antagonists. Synonyms: KW6002; KW 6002; KW-6002; Istradefylline. 8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione. Grades: > 95%. CAS No. 155270-99-8. Molecular formula: C20H24N4O4. Mole weight: 384.43.
Istradefylline
Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinsons disease. Group: Biochemicals. Alternative Names: (E) -8-[2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-Purine-2, 6-dione; Istradefylline; KW 6002. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Istradefylline
Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with K i of 2.2 nM in experimental models of Parkinson's disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KW-6002. CAS No. 155270-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10888.
Istradefylline Dimer 2 is a dimer of Istradefylline, which is a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione); 1H-Purine-2,6-dione, 8,8'-[(1α,2α,3β,4β)-2,4-bis(3,4-dimethoxyphenyl)-1,3-cyclobutanediyl]bis[1,3-diethyl-3,7-dihydro-7-methyl-; Istradefylline Impurity 25. CAS No. 702697-27-6. Molecular formula: C40H48N8O8. Mole weight: 768.86.
Istradefylline Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H23N3O5. Mole Weight: 373.41. Catalog: APB08264.
Istradefylline Impurity 21
Istradefylline Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H22N4O6. Mole Weight: 402.41. Catalog: APB08275.
Istradefylline Impurity 22
Istradefylline Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C30H32N4O9. Mole Weight: 592.61. Catalog: APB08277.
Istradefylline Impurity 23
Istradefylline Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C31H36N4O8. Mole Weight: 592.65. Catalog: APB08278.
Istradefylline Impurity 24
Istradefylline Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C40H50N8O8. Mole Weight: 770.89. Catalog: APB08279.
Istradefylline Impurity 3
Istradefylline Impurity 3 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H23N3O5. Mole weight: 373.40.
Istradefylline Impurity 4
Istradefylline Impurity 4 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C30H34N4O8. Mole weight: 578.61.
Istradefylline Impurity 4
Istradefylline Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-amino-1,3-diethyl-5-nitrosopyrimidine-2,4(1H,3H)-dione. CAS No. 89073-60-9. Molecular Formula: C8H12N4O3. Mole Weight: 212.21. Catalog: APB89073609.
Istradefylline Impurity 4
Istradefylline Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C8H16N4O3. Mole Weight: 216.24. Catalog: APB08282.
Istradefylline Impurity 5
Istradefylline Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-amino-3-ethyl-5-nitrosopyrimidine-2,4(1H,3H)-dione. Molecular Formula: C6H8N4O3. Mole Weight: 184.15. Catalog: APB01549.
Istradefylline Impurity 5
Istradefylline Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 146946-10-3. Molecular Formula: C8H12N4O4. Mole Weight: 228.21. Catalog: APB146946103.
Istradefylline Impurity 5
Istradefylline Impurity 5 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H22N4O6. Mole weight: 402.40.
Istradefylline Impurity 6
Istradefylline Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2700619-57-2. Molecular Formula: C8H16N4O2. Mole Weight: 200.24. Catalog: APB2700619572.
Istradefylline Impurity 6
Istradefylline Impurity 6 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Molecular formula: C19H23N3O5. Mole weight: 373.40.
Istradefylline Impurity 7
Istradefylline Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 187393-68-6. Molecular Formula: C19H24N4O5. Mole Weight: 388.42. Catalog: APB187393686.
Istradefylline Impurity 7
Istradefylline Impurity 7 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. CAS No. 1453190-01-6. Molecular formula: C20H24N4O4. Mole weight: 384.43.
Istradefylline Impurity 8
Istradefylline Impurity 8 is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: 3,4-Dimethoxycinnamamide; 14773-40-1; 3-(3,4-Dimethoxyphenyl)propenamide; (E)-3-(3,4-dimethoxyphenyl)prop-2-enamide; (2E)-3-(3,4-dimethoxyphenyl)prop-2-enamide; 130973-10-3; CINNAMAMIDE, 3,4-DIMETHOXY-; SCHEMBL8153880; SCHEMBL8153885; 3-(3,4-Dimethoxyphenyl)acrylamide; LT0108; AKOS003421127; NCGC00385957-01; (2E)-3-(3,4-dimethoxyphenyl)-2-propenamide; NCGC00385957-01_C11H13NO3_(2E)-3-(3,4-Dimethoxyphenyl)acrylamide. CAS No. 14773-40-1. Molecular formula: C11H13NO3. Mole weight: 207.23.
Istradefylline Impurity 8
Istradefylline Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H25N3O5. Mole Weight: 375.43. Catalog: APB08283.
Istradefylline Impurity 9
Istradefylline Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C31H38N4O8. Mole Weight: 594.67. Catalog: APB08284.
Istradefylline Impurity A
Istradefylline Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-N-(1,3-diethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-(3,4-dimethoxyphenyl)acrylamide. Molecular Formula: C19H23N3O5. Mole Weight: 373.4. Catalog: APB01553.
Istradefylline Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-N-(1,3-diethyl-5-nitroso-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-(3,4-dimethoxyphenyl)acrylamide. Molecular Formula: C19H22N4O6. Mole Weight: 402.4. Catalog: APB01551.