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| Product | Description | |
|---|---|---|
| Rofecoxib | Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC 50 s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC 50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17372. |  |
| Rofecoxib | Rofecoxib is a COX-2 inhibitor (IC50s = 26 nM and > 50 μM in human osteosarcoma cells). Uses: Cyclooxygenase 2 inhibitors. Synonyms: MK966; MK966; MK 966; MK0966; MK0966; MK 0966; Rofecoxib; brand name: Vioxx; Ceoxx; Ceeoxx. 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. Grades: > 95%. CAS No. 162011-90-7. Molecular formula: C17H14O4S. Mole weight: 314.4. |  |
| Roflumilast | Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC 50 s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1 , PDEA4 , PDEB1 , and PDEB2 , respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15455. | |
| Roflumilast | Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences. |  Worldwide |
| Roflumilast | 3-Cyclopropylomethoxy-n-(3,5 dichloropyridin-4-yl)-4-difluoro-methoxybenzamide. antiacne, antipsoriatric. CAS No. 162401-32-3. Product ID: 8-01416. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.21. |  |
| Roflumilast-d3 | Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(Cyclopropylmethoxy-d3)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d3; BY 217-d3; BYK 20869-d3. Product Category: Inhibitors. Appearance: Crystallin Solid. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. Canonical SMILES: [2H]C1(CC1)C([2H])([2H])OC2=C(C=CC(C(NC3=C(Cl)C=NC=C3Cl)=O)=C2)OC(F)F. Product ID: ACM1189992004. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Roflumilast-d4 | Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast-D4 | Roflumilast-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1398065-69-4. Molecular Formula: C17H10D4Cl2F2N2O3. Mole Weight: 407.23. Catalog: APB1398065694. |  |
| Roflumilast-d5 | Roflumilast-d5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H9D5Cl2F2N2O3. Mole Weight: 408.24. Catalog: APB12078. | |
| Roflumilast-d5 N-oxide | Roflumilast-d5 N-oxide. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H9D5Cl2F2N2O4. Mole Weight: 424.24. Catalog: APB12077. | |
| Roflumilast Dimer | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.42. | |
| Roflumilast Impurity 1 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast; Roflumilast Impurity A. Grades: > 95%. CAS No. 162401-43-6. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity 1 | Roflumilast Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 292135-78-5. Molecular Formula: C17H14Cl2F2N2O4. Mole Weight: 419.21. Catalog: APB292135785. | |
| Roflumilast Impurity 10 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H16F2N2O3. Mole weight: 334.33. | |
| Roflumilast Impurity 11 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21. | |
| Roflumilast Impurity 2 | Roflumilast Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1352122-37-2. Molecular Formula: C29H24Cl2F4N2O6. Mole Weight: 643.41. Catalog: APB1352122372. | |
| Roflumilast Impurity 2 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. | |
| Roflumilast Impurity 3 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)benzamide; 1391052-24-6; 3,4-Di(cyclopropylmethoxy) Roflumilast; BenzaMide, 3,4-bis(cyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)-; C20H20Cl2N2O3; 3,4-bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-benzamide; Roflumilast Impurity 3; DTXSID70747612; MFCD23703092; AKOS016012227; DS-6755; AC-28929; CS-0155388; C72553; A886144; A1-04290; 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)benzamide. Grades: > 95%. Molecular formula: C20H20Cl2N2O3. Mole weight: 407.29. | |
| Roflumilast Impurity 3 | Roflumilast Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391053-75-0. Molecular Formula: C17H15ClF2N2O3. Mole Weight: 368.76. Catalog: APB1391053750. | |
| Roflumilast Impurity 4 | Roflumilast Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H10F2O8. Mole Weight: 368.24. Catalog: APB12076. | |
| Roflumilast Impurity 4 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.13. | |
| Roflumilast Impurity 5 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21. | |
| Roflumilast Impurity 6 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H10F2O8. Mole weight: 368.25. | |
| Roflumilast Impurity 7 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14BrClF2N2O3. Mole weight: 447.67. | |
| Roflumilast Impurity 8 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity 9 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity B | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: 4-O-Des(difluoromethyl) Roflumilast; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: > 95%. CAS No. 475271-62-6. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.20. | |
| Roflumilast Impurity D | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Benzoic acid, 3-(cyclopropylmethoxy)-4-hydroxy-. CAS No. 1243391-44-7. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Roflumilast Impurity E | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-O-Decyclopropyl Roflumilast; Roflumilast metabolite M05; 3-(Hydroxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. CAS No. 1391052-76-8. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.11. | |
| Roflumilast Impurity H | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(difluoromethoxy) Roflumilast; Bis-difluoromethoxy Roflumilast impurity. CAS No. 162401-30-1. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.12. | |
| Roflumilast N-Oxide | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl- methoxybenzamide; 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide. Grades: > 95%. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast N-Oxide | Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Roflurane | Roflurane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bromo-2-trifluoro-1,1,2-ethyl-methyl ether; DA-893; Methyl-<1,1,2-trifluor-2-brom-aethyl>-aether; Ethane,2-bromo-1,1,2-trifluoro-1-methoxy; 1,1,2-Trifluor-2-bromethylmethylether; Rofluranum; Roflurano; Rofluran; 1,1,2-trifluoro-2-bromoethyl ether; R. Product Category: Heterocyclic Organic Compound. CAS No. 679-90-3. Molecular formula: C3H4BrF3O. Mole weight: 192.962. Purity: 0.96. IUPACName: 2-bromo-1,1,2-trifluoro-1-methoxyethane. Canonical SMILES: COC(C(F)Br)(F)F. Density: 1.687g/cm³. Product ID: ACM679903. Alfa Chemistry ISO 9001:2015 Certified. | |
| Rogaratinib | Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100019. | |
| Rogaratinib | Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Synonyms: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Molecular formula: C23H26N6O3S. Mole weight: 466.6. | |
| Roginolisib | Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC 50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827. | |
| R(OH), S-Metconazole ((1R,5S)-5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol) | Grades: > 95%. Molecular formula: C17H22ClN3O. Mole weight: 319.84. | |
| Rolapitant | Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751. | |
| Rolapitant | Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant | Rolapitant. Uses: For analytical and research use. Group: Impurity standards. CAS No. 552292-08-7. Molecular Formula: C25H26F6N2O2. Mole Weight: 500.49. Catalog: APB552292087. | |
| Rolapitant (1R,2R,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453123; EX-A1288F; Rolapitant (1R,2R,3R)-Isomer; FIVSJYGQAIEMOC-XARZLDAJSA-N; (5R, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-26-0. Grades: > 95%. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1R,2R,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453121; EX-A1288E; Rolapitant (1R,2R,3S)-Isomer; FIVSJYGQAIEMOC-AVIJNYRZSA-N; (5S, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-25-9. Grades: > 95%. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1R,2S,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL12679453; EX-A1288G; Rolapitant (1R,2S,3R)-Isomer; FIVSJYGQAIEMOC-UZFJHSOTSA-N; (5R, 8S) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 552292-73-6. Grades: > 95%. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2R,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Grades: > 95%. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2R,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453127; EX-A1288D; Rolapitant (1S,2R,3S)-Isomer; FIVSJYGQAIEMOC-FNVCAUGXSA-N; (5S, 8R) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-28-2. Grades: > 95%. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2S,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: Rolapitant (1S,2S,3R)-Isomer. Grades: > 95%. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2S,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453126; EX-A1288H; Rolapitant (1S,2S,3S)-Isomer; FIVSJYGQAIEMOC-PBNUPURSSA-N; HMS3750I21; (5S, 8S) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-27-1. Grades: > 95%. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant HCl hydrate | Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and late-phase CINV during the first 120 hours post-chemotherapy. Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[4. 5]decan-2-one hydrochloride.; SCH619734 SCH-619734; SCH 619734; Rolapitant HCl; Rolapitant hydrochloride, Rolapitant, brand name: Varubi. CAS No. 914462-92-3. Molecular formula: C25H26F6N2O2.ClH.H2O. Mole weight: 554.95. | |
| Rolapitant hydrochloride hydrate | Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734 hydrochloride hydrate. CAS No. 914462-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16436. | |
| Rolapitant Impurity 1 | Rolapitant Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H22D4F6N2O2. Mole Weight: 504.51. Catalog: APB11169. | |
| Rolapitant Impurity 4 | Rolapitant Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 552292-73-6. Molecular Formula: C25H26F6N2O2. Mole Weight: 500.49. Catalog: APB552292736. | |
| Roletamide | Roletamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Roletamide;3-(2,5-Dihydro-1H-pyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one;CL 59112. Product Category: Heterocyclic Organic Compound. CAS No. 10078-46-3. Molecular formula: C16H19NO4. Purity: 0.96. IUPACName: (E)-3-(2,5-dihydropyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)C=CN2CC=CC2. Density: 1.203g/cm³. Product ID: ACM10078463. Alfa Chemistry ISO 9001:2015 Certified. | |
| Rolinsatamab | Rolinsatamab is a humanized bispecific monoclonal antibody targeting both IL-4 and IL-13. CAS No. 2095467-30-2. | |
| Rolipram | Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC 50 s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900. | |
| Rolipram | Rolipram is a selective PDE4 inhibitor that modulates cyclic AMP (cAMP) degradation. Study showed that rolipram induced neuronal differentiation of human bone marrow-mesenchymal stem cells (hBM-MSCs). It can be used as an anti-inflammatory agent. Uses: Antidepressive agents. Synonyms: ZK-62711; SB 95952; 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one. Grades: >98%. CAS No. 61413-54-5. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| Rolipram | Rolipram. Group: Biochemicals. Grades: Purified. CAS No. 61413-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Rolipram (4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| rolitetracycline | Rolitetracycline is a semi-synthetic tetracycline antibiotic. It has broad-spectrum Gram-positive activity in the body. Uses: Antibacterial. Synonyms: Reverin; Syntetrin; Rolitetraciclina; Rolitetracyclinum; Pyrrolidino-Methyl-Tetracycline. Grades: >98% by HPLC. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.56. | |
| Rolitetracycline | Rolitetracycline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12,12a-pentahydroxy-6-methyl-1,11-dioxo-n-(1-pyrrolidinylmethyl)-1;bristacin;n-(1-pyrrolidinylmethyl)-tetracycline;n-(pyrrolidinomethyl)tetracycline;pirrolidinometil-tetraciclina;prm-tc;pyrrolidinomethyl-tetracyclin;pyrrolidino-methyl-tetracycline. Product Category: Heterocyclic Organic Compound. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.57. Product ID: ACM751973. Alfa Chemistry ISO 9001:2015 Certified. | |
| Rolitetracycline | Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic [1] [2]. Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 751-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-18257. | |
| Rolitetracycline (Pyrrolidinyl methyl tetracycline, SQ 15659) | Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable. Group: Biochemicals. Alternative Names: (4S, 4aS, 5aS, 6S, 12aS) -4- (di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; 4- (Di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; Abricycline; Bristacin; N- (1-Pyrrolidinylmethyl) tetracycline; N- (Pyrrolidinomethyl) tetracycline; Pyrrolidinyl methyl tetracycline; Reverin; Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin; Transcycline; Velacycline. Grades: Technical Grade. CAS No. 751-97-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 527.57. US Biological Life Sciences. | Worldwide |
| Rolofylline | Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 ( CYP 450 ) [1]. Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KW-3902. CAS No. 136199-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10965. | |
| Rolofylline metabolite M1-cis | Rolofylline metabolite M1-cis, an active metabolite of Rolofylline, is a potent and selective adenosine A1 receptor antagonist. Synonyms: Rolofylline metabolite M1-cis; Rolofylline metabolite M1-trans; 160943-06-6; 161167-65-3; SCHEMBL3263501; L011792; 8-(Hexahydro-7-hydroxy-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-1H-Purine-2,6-dione, cis; 8-(Hexahydro-7-hydroxy-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-1H-Purine-2,6-dione, trans. Grades: 98%. CAS No. 161167-65-3. Molecular formula: C20H28N4O3. Mole weight: 372.46. | |
| Rolofylline metabolite M1-trans | Rolofylline metabolite M1-trans, an active metabolite of Rolofylline, is a potent and selective adenosine A1 receptor antagonist. Grades: 99%. CAS No. 160943-06-6. Molecular formula: C20H28N4O3. Mole weight: 372.46. | |
| Roluperidone | Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT 2A and sigma-2 receptors ( K i of 7.53 nM and 8.19 nM for 5-HT 2A and sigma-2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYR-101; MIN-101; MT-210. CAS No. 359625-79-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19469. | |
| Romandolide® | Romandolide®. CAS No. 236391-76-7. VIGON Item # 504005. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Romascone® | Romascone®. CAS No. 81752-87-6. VIGON Item # 502837. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, damascone carboxylate. | America & Internationally |
| Romidepsin | Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC 50 s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively [1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK 228; FR 901228; NSC 630176. CAS No. 128517-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15149. | |
| Romidepsin | Romidepsin Inhibitor. Uses: Scientific use. Product Category: T6006. CAS No. 128517-07-7. |  |
| Romidepsin | Romidepsin. Group: Biochemicals. Alternative Names: (1S,4Z,7S,10S,11E,20R)-4-Ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3, 6, 18, 21-tetrazabicyclo[8. 7. 6]tricos-11-ene-2, 5, 8, 19, 22-pentone; Depsipeptide; FK228. Grades: Highly Purified. CAS No. 128517-07-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H36N4O6S2. US Biological Life Sciences. | Worldwide |
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