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| Product | Description | |
|---|---|---|
| Rutin | Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside; Quercetin 3-O-rutinoside. CAS No. 153-18-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-N0148. |  |
| Rutin | Rutin is colored brown by tobacco enzyme under experimental conditions. In medicine, it has been used as an auxiliary drug and nutritional supplement for the treatment of cardiovascular system diseases. Because it is not toxic to the human body, it can also be used as an antioxidant and natural edible yellow pigment in the food industry. Uses: Adcs cytotoxin. Synonyms: 4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; Flavone, 3,3',4',5,5',7-hexahydroxy-, (6-O-α-L-rhamnosyl-β-D-glucoside); Ilixanthin; 3,3',4',5,7-Pentahydroxyflavone 3-O-rutinoside; 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside; 3-O-Rutinosylquercetin; 3-Rutinosylquercetin; 5,7,3',4'-Tetrahydroxyflavonol-3-O-rutinoside; Birutan; C.I. 75730; Eldrin; Globulariacitrin; Globularicitrin; Ilixathin; Melin; Myrticalorin; Myrticolorin; Myticolorin; Novarrutina; NSC 9220; Osyritin; Osyritrin; Oxyritin; Paliuroside; Phytomelin; Quercetin 3-(6-O-α-L-rhamnopyranosyl-β-D-glucopyranoside); Quercetin 3-O-rutinoside; Quercetin 3-O-α-L-rhamnopyranosyl-(1?6)-β-D-glucopyranoside; Quercetin 3-O-β-D-rutinoside; Quercetin 3-rhamnoglucoside; Quercetin 3-rutinoside; Quercetin 3-β-rutinoside; Quercetin 6-O-α-L-rhamnosyl-β-D-glucoside; Quercetin rutinoside; Rutabion; Rutine; Rutinic acid; Rutosid; Rutoside; Rutozid; Sophorin; Tanrutin; TCI-R 0035; TCM 5280805; Violaquercetrin; Violaquercitrin; Yunxianggan. Grades: >95% by HPLC. CAS No. 153-18-4. Molecular formula: C27H30O16. Mole weight: 610.53. |  |
| Rutin | Rutin - Product ID: NST-10-117. Category: Flavonoids. Alternative Names: 3-Rutinosylquercetin, Birutan, Eldrin, Globulariacitrin, Ilixathin, Melin, Myrticalorin, Novarrutina, Osyritin, Paliuroside, Phytomelin, Quercetin rutinoside, Rutinic acid, Rutoside, Sophorin, Tanrutin. Purity: 95%. Test method: HPLC. CAS No. 153-18-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Yellow Powder. Molecular formula: C27H30O16. Mole weight: 610.52. Storage: +2 +8 °C. |  |
| Rutin | Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside between the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6))-β-D-glucopyranose). In the fava danta tree, the synthesis is done via a rutin synthase activity. Group: Inhibitors. Alternative Names: Globularicitrin. CAS No. 153-18-4. Molecular formula: C27H30O16. Mole weight: 610.52. Appearance: Yellow to green powder. Purity: 0.97. IUPACName: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one. Canonical SMILES: CC1C (C (C (C (O1)OCC2C (C (C (C (O2)OC3=C (OC4=CC (=CC (=C4C3=O)O)O)C5=CC (=C (C=C5)O)O)O)O)O)O)O)O. Density: 1.3881 g/cm³. ECNumber: 205-814-1. Catalog: ACM153184. |  |
| Rutin | Rutin. Categories: rutin; 153-18-4. |  CA, FL & NJ |
| Rutin hydrate | Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate. CAS No. 207671-50-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0148A. | |
| Rutin Hydrate | Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress. Group: Inhibitors. CAS No. 207671-50-9. Molecular formula: C27H36O19. Mole weight: 664.6. Appearance: Solid. Purity: 0.98. Canonical SMILES: O=C1C (O[C@H]2[C@@H] ([C@H] ([C@@H] ([C@@H] (CO[C@H]3[C@@H] ([C@@H] ([C@H] ([C@H] (C)O3)O)O)O)O2)O)O)O)=C (C4=CC=C (O)C (O)=C4)OC5=CC (O)=CC (O)=C15. O. [36/5]. Catalog: ACM207671509. | |
| Rutinose | Rutinose is a naturally occurring saccharide prevalent in multifarious plant species, exhibiting immense application as a key constituent in developing drug formulation targeted towards cardiovascular ailments, inflammatory disorders and diabetic conditions. Synonyms: 6-O-(Deoxy-a-L-mannopyranosyl)-D-glucopyranose; 6-O-(a-L-Rhamnopyranosyl)-D-glucopyranose. CAS No. 90-74-4. Molecular formula: C12H22O10. Mole weight: 326.3. | |
| Rutin, Powder | Rutin, Powder. Synonyms: 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside, 3-Rutinosylquercetin, Globulariacitrin, Ilixanthi, Myrticalorin, Osyritrin, Paliuroside, Phytomelin, Quercetin 3-rhamnoglucoside, Quercetin 3-rutinoside, Rutoside, Sophorin, Tanrutin, Violaquercitrin. CAS No. 153-18-4. Product ID: CDC10-0067. Molecular formula: C27H30O16. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Rutin, Powder; CDC10-0067; 153-18-4; C27H30O16; Tanrutin, Violaquercitrin; 205-814-1; MFCD00006830; 153-18-4. Grade: Primary reference standard. Purity: ≥95.0% (HPLC). Color: yellow to green. EC Number: 205-814-1. Physical State: Powder. Solubility: pyridine: 50 mg/mL. Storage: Keep in dark place,Sealed in dry,2-8°C. Boiling Point: 576.13°C (rough estimate). Melting Point: 195 °C (dec.)(lit.). Density: 1.3881 g/cm3(rough estimate). |  |
| Rutin (Standard) | Rutin (Standard) is the analytical standard of Rutin. This product is intended for research and analytical applications. Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 153-18-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0148R. | |
| rutin sulfate | rutin sulfate. CAS No. 108916-86-5. Catalog: ACM108916865. | |
| Rutin trihydrate | Rutin trihydrate is an extensively employed pharmaceutical component revered for its remarkable antioxidative is anti-inflammatory and anticancer attributes. Rutin trihydrate unequivocally assumes a pivotal role in studying diverse afflictions encompassing cardiovascular maladies, diabetes Mellitus and neoplastic pathologies. Synonyms: Quercetin-3-rutinoside hydrate; 3-[[6-O-(6-Deoxy-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-4H-1-benzopyran-4-one; Vitamin P hydrate; (+)-Rutin trihydrate. CAS No. 250249-75-3. Molecular formula: C27H30O16 3H2O. Mole weight: 664.56. | |
| Rutin trihydrate | 100g Pack Size. Group: Biochemicals, Building Blocks, Organics, Research Organics & Inorganics. Formula: C27H30O16 · 3H2O. CAS No. 250249-75-3. Prepack ID 20684965-100g. Molecular Weight 664.56. See USA prepack pricing. |  |
| Rutin trihydrate | Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate. CAS No. 250249-75-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W013075. | |
| Rutinulose | Rutinulose is an organic substance present in select botanical sources and fruits, exhibiting its profound anti-inflammatory attributes along with robust antioxidant characteristics. Synonyms: 6-O-(a-LRhamnopyranosyl)-D-glucopyranose; 6-O-(6-Deoxy-a-L-mannopyranosyl)-D-glucopyranose. CAS No. 1360593-47-0. Molecular formula: C12H22O10. Mole weight: 326.30. | |
| Ruxolitinib | Ruxolitinib (INCB18424) is an orally active and selective JAK1/2 inhibitor with IC 50 s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 [1]. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB18424. CAS No. 941678-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50856. | |
| Ruxolitinib | Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy. Group: Inhibitors. Alternative Names: Ruxolitinib; (R)-3-(4-(7H-Pyrrolo[2, 3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; 1H-Pyrazole-1-propanenitrile. beta.-cyclopentyl-4-(7H-pyrrolo[2, 3-d]pyriMidin-4-yl)-, (.beta.R)-; (3R)-3-(4-(7H-pyrrolo[2, 3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2, 3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile; INCB018424 (Ruxolitinib);Jakafi. CAS No. 941678-49-5. Molecular formula: C17H18N6. Mole weight: 306.371. Purity: 0.9997. Density: 1.4. Catalog: ACM941678495. | |
| Ruxolitinib | Ruxolitinib Inhibitor. Uses: Scientific use. Product Category: T1829. CAS No. 941678-49-5. |  |
| Ruxolitinib | Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3. Synonyms: (R)-Ruxolitinib; INCB018424; R-INCB018424; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. Grades: >98%. CAS No. 941678-49-5. Molecular formula: C17H18N6. Mole weight: 306.37. | |
| Ruxolitinib | Ruxolitinib Inhibitor. Uses: Scientific use. Product Category: T3043. CAS No. 1092939-17-7. | |
| Ruxolitinib-alkyne | Ruxolitinib-alkyne is a derivative of Ruxolitinib (R702000), which is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis. Ruxolitinib-alkyne is prepared as a racemic mixture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H19N5, Molecular Weight: 305.38. US Biological Life Sciences. |  Worldwide |
| Ruxolitinib-azide | Ruxolitinib-azide is a derivative of Ruxolitinib (R702000), which is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H20N8, Molecular Weight: 336.39. US Biological Life Sciences. | Worldwide |
| Ruxolitinib, Free Base | Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC50's of 2.7 and 4.5nm for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis. Group: Biochemicals. Alternative Names: (b-R)-b-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; INCB018424, INC18424, NCB018424, NCB18424. Grades: Purified. CAS No. 941678-49-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Ruxolitinib impurity 1 | Ruxolitinib impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2606144-44-7. Molecular Formula: C16H18N6O2. Mole Weight: 326.36. Catalog: APB2606144447. |  |
| Ruxolitinib impurity 3 | Ruxolitinib impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 941685-37-6. Molecular Formula: C17H18N6. Mole Weight: 306.37. Catalog: APB941685376. | |
| Ruxolitinib impurity 4 | Ruxolitinib impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C35H34N12. Mole Weight: 622.74. Catalog: APB11154. | |
| Ruxolitinib impurity 5 | Ruxolitinib impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H23BN2O3. Mole Weight: 266.15. Catalog: APB11153. | |
| Ruxolitinib Impurity 5 (Lithium) | Ruxolitinib Impurity 5 (Lithium). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: lithium (R)-4-amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylate. Molecular Formula: C16H17LiN6O2. Mole Weight: 332.29. Catalog: APB01761. | |
| Ruxolitinib impurity 6 | Ruxolitinib impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H18N6O. Mole Weight: 322.37. Catalog: APB11156. | |
| Ruxolitinib impurity 7 | Ruxolitinib impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H18N6O. Mole Weight: 322.37. Catalog: APB11155. | |
| Ruxolitinib impurity 8 | Ruxolitinib impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2606144-45-8. Molecular Formula: C16H18N6O. Mole Weight: 310.36. Catalog: APB2606144458. | |
| Ruxolitinib impurity 9 | Ruxolitinib impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1315607-85-2. Molecular Formula: C17H18N6O. Mole Weight: 322.37. Catalog: APB1315607852. | |
| Ruxolitinib phosphate | Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Synonyms: INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate. Grades: >98%. CAS No. 1092939-17-7. Molecular formula: C17H21N6O4P. Mole weight: 404.36. | |
| Ruxolitinib phosphate | Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC 50 s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB018424 phosphate. CAS No. 1092939-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50858. | |
| Ruxolitinib sulfate | Ruxolitinib sulfate (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Synonyms: Ruxolitinib sulfate; 1092939-16-6; INCB018424 sulfate; beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(betaR)-1H-pyrazole-1-propanenitrile, (2Z)-2-butenedioate); SCHEMBL22127335; BCP27733; FT-0770538; 1092939-15-5; A921922; INCB018424 sulfate; INCB 018424 sulfate; INCB-018424 sulfate; 3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile; sulfuric acid. Grades: >98%. CAS No. 1092939-16-6. Molecular formula: C17H20N6O4S. Mole weight: 404.44. | |
| Ruzinurad | Ruzinuradum is a urate transporter inhibitor. Synonyms: ruzinuradum. Grades: >98%. CAS No. 1638327-48-6. Molecular formula: C14H12BrNO2S. Mole weight: 338.22. | |
| RV-23 | RV-23 is an antibacterial peptide isolated from Rana draytonii. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. RV-23 is a cell-selective antibacterial peptide with high hemocompatibility due to its unique structure. Synonyms: Arg-Ile-Gly-Val-Leu-Leu-Ala-Arg-Leu-Pro-Lys-Leu-Phe-Ser-Leu-Phe-Lys-Leu-Met-Gly-Lys-Lys-Val. Grades: >97%. Molecular formula: C126H219N33O25S. Mole weight: 2628.39. | |
| rvastatin Impurity 43 | rvastatin Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 4-(1b-(4-fluorophenyl)-7-hydroxy-7-isopropyl-1a-phenyl-7a-(phenylcarbamoyl)hexahydro-1aH-oxireno[2',3':3,4]pyrrolo[2,1-b][1,3]oxazin-3-yl)-3-hydroxybutanoate 4-(6a-(4-fluorophenyl)-7-hydroxy-1a-isopropyl-7-phenyl-7a-(phenylcarbamoyl)hexahydro-1aH-o. Molecular Formula: C33H34FN2NaO7. Mole Weight: 612.62. Catalog: APB02549. | |
| RVD-Hpα | RVD-Hpα is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. CAS No. 1193362-76-3. Molecular formula: C65H105N19O17. Mole weight: 1424.66. | |
| RVD-Hpα acetate | RVD-Hpα acetate is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. It is also a high-affinity CB2 positive allosteric modulator (Ki = 50 nM). Synonyms: H-Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-arginyl-L-valyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine. Grades: ≥95%. Molecular formula: C67H109N19O19. Mole weight: 1484.71. | |
| R-Venlafaxine | R-Venlafaxine. Group: Biochemicals. Alternative Names: 1-[ (1R) -2- (Dimethylamino) -1- (4-methoxyphenyl) ethyl]cyclohexanol; (+)-Venlafaxine. Grades: Highly Purified. CAS No. 93413-46-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H27NO2. US Biological Life Sciences. | Worldwide |
| R-Venlafaxine-di-p-toluoyl-D-tartrate Salt | A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 272788-00-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| R-Verapamil HCl | R-Verapamil HCl is an inhibitor of the p-glycoprotein efflux pump in multidrug resistant tumor cells. Synonyms: (R)-(+)-Verapamil Hydrochloride; (α R) -α -[3-[[2- (3, 4-Dimethoxyphenyl) ethyl]methylamino]propyl]-3, 4-dimethoxy-α - (1-methylethyl) -benzeneacetonitrile Hydrochloride; (R)-Verapamil Hydrochloride; Dexverapamil Hydrochloride; LU 33925; NSC 632821. CAS No. 38176-02-2. Molecular formula: C27H38N2O4. HCl. Mole weight: 491.07. | |
| RVG-9R | RVG-9R, a chimeric rabies virus glycoprotein fragment, binds and transduces siRNA in vitro into neuronal cells, resulting in highly efficient gene silencing. Repeated administration of RVG-9R-bound siRNA did not induce inflammatory cytokines or anti-peptide antibodies. Synonyms: Rabies Virus Glycoprotein (194-221) Nonaarginine Chimer; H-Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly-Gly-Gly-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH. Grades: ≥95%. CAS No. 1678417-57-6. Molecular formula: C201H334N82O55S2. Mole weight: 4843.51. | |
| RVT-501 | RVT-501, also referred to E6005, is a selective phosphodiesterase 4 (PDE4) inhibitor (IC50 = 2.8 nM) with potential effect to treat atopic dermatitis. Synonyms: E-6005; E6005; E6005; RVT-501; RVT501; RVT 501; lotamilast; methyl 4-[[3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl]carbamoyl]benzoate; E6005; methyl 4-(((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)amino)carbonyl)benzoate. CAS No. 947620-48-6. Molecular formula: C26H24N4O5. Mole weight: 472.49. | |
| RVX-208 | RVX-208 is a potent inhibitor of BET bromodomains. RVX-208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. Using binding assays and X-ray crystallography, we now show that RVX-208 selectively binds to bromodomains of the BET (Bromodomain and Extra Terminal) family, competing for a site bound by the endogenous ligand, acetylated lysine, and that this accounts for its pharmacological activity. siRNA experiments further suggest that induction of ApoA-I mRNA is mediated by BET family member BRD4. These data indicate that RVX-208 increases ApoA-I production through an epigenetic mechanism and suggests that BET inhibition may be a promising new approach to the treatment of atherosclerosis. Synonyms: RVX208; RVX 208; RVX-208; Apabetalone. Grades: >98%. CAS No. 1044870-39-4. Molecular formula: C20H22N2O5. Mole weight: 370.40. | |
| RVX297 | RVX297 is a BD2 selective inhibitor of BET bromodomains. It is structurally related to the clinical compound RVX-208. It has significant implications on differential gene expression, which possibly can be further linked to the specific disease indication. It is currently undergoing phase III clinical trials for the treatment of cardiovascular diseases. Uses: Rvx297 is used for the treatment of cardiovascular diseases. Synonyms: RVX-297; RVX 297; RVX297. 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one. Grades: >98 %. CAS No. 1044871-04-6. Molecular formula: C24H29N3O4. Mole weight: 423.51. | |
| RW3 | RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration ( MIC ). RW3 can be used in antimicrobial and antifungal studies [1]. Uses: Scientific research. Group: Peptides. CAS No. 359632-11-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10281. | |
| RWJ 21757 | RWJ 21757. Group: Biochemicals. Grades: Purified. CAS No. 121288-39-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ 50271 | RWJ 50271. Group: Biochemicals. Grades: Purified. CAS No. 162112-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ 50271 | RWJ 50271 is a selective inhibitor of LFA-1/ICAM-1 mediated cell adhesion (sICAM) (IC50= 5 μM in HL60 cells). Synonyms: N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide. Grades: ≥99% by HPLC. CAS No. 162112-37-0. Molecular formula: C18H17F3N4O2S. Mole weight: 410.41. | |
| RWJ 52353 | RWJ 52353. Group: Biochemicals. Grades: Purified. CAS No. 245744-10-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RWJ 52353 | RWJ 52353 is an α2 agonist with analgesic activity (Ki= 1.5, 254, 443 and 621 nM for α2D, α2A, α1 and α2B adrenergic receptors respectively). Synonyms: RWJ 52353; RWJ52353; RWJ-52353; 5-(6,7-Dihydrobenzo[b]thien-4-yl-1H-imidazole hydrochloride. Grades: ≥98% by HPLC. CAS No. 245744-10-9. Molecular formula: C11H10N2S. Mole weight: 202.28. | |
| RWJ 52353 hydrochloride | RWJ 52353 is an agonist of α2D-adrenergic receptors (α2D-ARs) with Ki value of 1.5 nM. It also exhibits agonist activity against α2A-, α2B-, and α1-ARs with Ki values of 254, 621, and 443 nM, respectively. Synonyms: 5-(6,7-dihydro-1-benzothiophen-4-yl)-1H-imidazole hydrochloride. Grades: ≥98%. CAS No. 245744-13-2. Molecular formula: C11H10N2S·HCl. Mole weight: 238.7. | |
| RWJ 56110 | RWJ 56110. Group: Biochemicals. Grades: Purified. CAS No. 252889-88-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| RWJ 56110 | RWJ 56110 is a selective Thrombin R protease-activated receptor (PAR)-1 antagonist which exhibits no activity at PAR2, PAR3, or PAR4 subtypes. It blocks thrombin-induced platelet aggregation and activation of MAPK in HUVECs. Synonyms: (α S)-N-[ (1S)-3-Amino-1-[[ (phenylmethyl)amino]carbonyl]propyl]-α -[[[[1-[ (2, 6-dichlorophenyl)methyl]-3- (1-pyrrolidinylmethyl)-1H-indol-6-yl]amino]carbonyl]amino]-3, 4-difluoro-benzenepropanamide; RWJ-56110; RWJ 56110; RWJ56110. Grades: ≥96% by HPLC. CAS No. 252889-88-6. Molecular formula: C41H43Cl2F2N7O3.2HCl. Mole weight: 863.65. | |
| RWJ 67657 | RWJ 67657 is an orally active inhibitor of the MAP kinases p38alpha and p38beta (IC50s = 1 and 11 uM, respectively, in vitro) that is inactive against p38gamma and p38delta, as well as several other kinases. It blocks the release of TNF-alpha and IL-1beta from peripheral blood mononuclear cells stimulated with LPS (IC50s = 3 and 11 nM, respectively) and inhibits TNF-alpha production in LPS-treated mice and rats. RWJ 67657 potently blocks the proliferation of CD4+ peripheral blood T cells induced by CD28 stimulation alone (IC50 = 0.5-4nM). It is commonly used to study the roles of p38alpha and p38beta in cellular and whole animal systems. Group: Biochemicals. Alternative Names: 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol; 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-Pyridyl)imidazole; JNJ 3026582; RWJ 67657. Grades: Highly Purified. CAS No. 215303-72-3. Pack Sizes: 1mg, 5mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ-67657 | RWJ-67657 is a p38 mitogen-activated protein-kinase (p38MAPK) inhibitor. RWJ 67657 has been shown to inhibit chemokine production and E-selectin expression in activated endothelial cells. Synonyms: RWJ 67657; RWJ67657; 3-Butyn-1-ol, 4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl)-. Grades: 98%. CAS No. 215303-72-3. Molecular formula: C27H24FN3O. Mole weight: 425.51. | |
| Rw yellow h3g | Heterocyclic Organic Compound. CAS No. 12239-48-4. Purity: 0.96. Catalog: ACM12239484. | |
| RX-3117 | RX-3117, also known as TV-1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX-3117 is taken up by cells through a carrier-mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX-DP) and triphosphate forms (RX-TP). The triphosphate form is incorporated into RNA and inhibits RNA synthesis. The diphosphate RX-DP is reduced by ribonucleotide reductase (RR) to dRX-DP; its triphosphate form (dRX-TP) is incorporated into DNA. In addition, RX-3117 also inhibits DNA methyltransferase 1 (DNMT1). This eventually leads to cell cycle arrest and the induction of apoptosis. UCK is the rate-limiting enzyme in the pyrimidine-nucleotide salvage pathway. Synonyms: RX3117; RX 3117; TV-1360; TV1360; TV 1360; fluorocyclopentenylcytosine. Grades: >98%. CAS No. 865838-26-2. Molecular formula: C10H12FN3O4. Mole weight: 257.221. | |
| RX-3117 | RX-3117 (TV-1360) is a potent and orally active anticancer and antimetabolite agent. RX-3117 inhibits DNA methyltransferase 1 (DNMT1). RX-3117 shows antiproliferative and anti-tumour activity. RX-3117 induces cell cycle arrest at S phase and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV-1360; Fluorocyclopentenylcytosine. CAS No. 865838-26-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15228. | |
| Rx 821002 | Heterocyclic Organic Compound. Alternative Names: 2-methoxy-idazoxan; 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; 1H-Imidazole,2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro; 2-(2-methoxy-3H-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole. CAS No. 102575-24-6. Molecular formula: C12Cl1H15N2O3. Mole weight: 270.71. Purity: >99 %. IUPACName: 2-(3-methoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole. Density: 1.34g/cm³. Catalog: ACM102575246. | |
| RX 821002 hydrochloride | RX 821002 hydrochloride is a selective and potent α2-adrenoceptor antagonist, which exhibits selectivity for the α2D over the α2A subtypes (pKd= 9.7 and 8.2 respectively). Synonyms: RX821002 hydrochloride; RX-821002 hydrochloride; 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; 1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1); 1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride; 2-(2-Methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; 2-Methoxyidazoxan monohydrochloride. Grades: ≥99% by HPLC. CAS No. 109544-45-8. Molecular formula: C12H14N2O3.HCl. Mole weight: 270.72. | |
| RX 821002 hydrochloride | RX 821002 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 109544-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RXFP1 Agonist (2-Isopropoxy-N- (2- (3- (trifluoro methyl sulfonyl) phenylcarbamoyl) phenyl) benzamide, LGR7 Agonist, Relaxin/Insulin-like Family Peptide Receptor 1 Agonist, Leucine-Rich Repeat-Containing GPCR 7 Agonist) | A cell-permeable 2-acetamido-N-phenylbenzamide that selectively activates human, but not mouse, LGR7/RXFP1-mediated cAMP induction (EC50 = 200nM in THP1) via allosteric interaction with the ECL3 region without competing against ECL2-mediated relaxin binding or affecting AVPR1B- or LGR8/RXFP2-mediated cAMP induction. Although shown to be ~150-fold and 500-fold less potent than relaxin (RLX), respectively, in VEGF mRNA induction and cellular impedance assays, pharmacokinetic studies reveal superior in vivo stability to RLX and in vivo bioavailability in mice via oral (Cmax/Tmax = 604nM/plasma/1h and 1026ng/g heart/1.5h; 30mg/kg) or intraperitoneal (Cmax/Tmax = 9.29uM/plasma/1h and 28.6uMol/kg heart/1h; 30mg/kg) administration with good aqueous solubility (7uM in PBS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RY785 | RY785 is a selective inhibitor of voltage-gated potassium channels with preference for Kv2.1 (IC50 = 0.05 μM). Synonyms: HY-114608; CS-0063544; 3-(3-methoxyphenyl)-2-methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-yl)propanamide hydrochloride. Grades: ≥98%. CAS No. 1393748-80-5. Molecular formula: C21H20N4O2S. Mole weight: 392.5. | |
| RY785 | RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 μM) that does not affect Cav2 calcium channels. Group: Inhibitors. Alternative Names: RY785; RY-785; RY 785. CAS No. 1393748-80-5. Molecular formula: C21H20N4O2S. Mole weight: 392.48. Appearance: Solid powder. Purity: >98%. IUPACName: 3-methoxy-α-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-benzenepropanamide. Canonical SMILES: O=C (NC1=CC=C2N=C (C3=CSC=N3)NC2=C1)C (C)CC4=CC=CC (OC)=C4. Catalog: ACM1393748805. | |
| Ryanodine | Heterocyclic Organic Compound. CAS No. 015662-33-6. Purity: N/A. Catalog: ACM015662336. | |
| Ryanodine | Ryanodine. Group: Biochemicals. Grades: Purified. CAS No. 15662-33-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ryanodine | Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca 2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Uses: Scientific research. Group: Natural products. CAS No. 15662-33-6. Pack Sizes: 1 mg. Product ID: HY-103306. | |
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