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| Product | Description | |
|---|---|---|
| SAvPhire Monomeric Streptavidin | recombinant, expressed in E. coli, High Affinity. Group: Fluorescence/luminescence spectroscopy. |  |
| Saw Palmeto Berry Extract (Standard) | Saw Palmetto (Serenoa Repens): The medicinal parts are the partially dried ripe fruit, the ripe fresh fruit and the ripe dried fruit, The plant is indigenous to the coastal regions of the southern states of the U.S., from South Carolina to Florida and southern California. Applications: Anti-androgenic effects: the lipophilic extract of the herb inhibits binding of dihydrotestosterone (dht) to the cytosolic androgenic receptor and alpha-1 adrenergic receptor in the prostate, thus preventing accumulation of the steroid, which may lead to prostate hyperplasia.anti-inflammatory effects: the extracts of the herb have demonstrated anti-inflammatory activity. inhibition of the synthesis of arachidonic acid inflammatory metobolits, through a double blocking of cyclooxygenas and 5-lipoxy-genase pathways results in anti-inflammatory properties. Group: Others. Purity: 25.0%,45.0% Fatty Acids GC. Saw Palmeto Berry Extract (Standard). Cat No: EXTW-014. |  |
| Saw Palmetto Berry P.E. 45% Fatty Acids GC | Saw Palmetto Berry P.E. 45% Fatty Acids GC. |  CA, FL & NJ |
| Saw Palmetto Extract | Saw palmetto extract is prepared from the the fruit of serenoa repens, which is the sole species currently classified in the genus Serenoa. Saw palmetto extract is rich in fatty acid and phytosterols. Saw palmetto extract has been used in traditional medicine for a variety of indications, most notably benign prostatic hyperplasia. Group: Others. Saw Palmetto Extract; Serenoa Repens (Bartram) Small. Cat No: EXTC-021. | |
| Saw Palmetto Extract | Saw Palmetto Extract is produced from the fruits of Serenoa serrulata. These fruit extracts are claimed to be effective treatments for seborrhoea, moisturizing, acne and hair loss. Uses: Designed for use in research and industrial production. Additional or Alternative Names: sabal serrulata extract;SAW PALMETTO EXTRACT;SERENOA EXTRACT;Sabal serrulatum, ext.;SERENOA SERRULATA FRUIT EXTRACT;Einecs 283-292-4;Extract of saw palmetto;Prosta urgenin. Product Category: Heterocyclic Organic Compound. CAS No. 84604-15-9. Molecular formula: Unspecified. Mole weight: Unspecified. Product ID: ACM84604159. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Saw Palmetto Powder & P.E. 4:1 | Saw Palmetto Powder & P.E. 4:1. | CA, FL & NJ |
| Saxagliptin | Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118. CAS No. 361442-04-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10285. |  |
| Saxagliptin | Saxagliptin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Onglyza; (1R,3S,5R)-2-((S)-2-amino-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Product Category: Steroidal Compounds. CAS No. 361442-04-8. Molecular formula: C18H25N3O2. Mole weight: 315.41. Purity: 95%+. IUPACName: Saxagliptin. Density: 1.35g/cm³. Product ID: ACM361442048. Alfa Chemistry ISO 9001:2015 Certified. | |
| Saxagliptin | Saxagliptin is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Uses: Dipeptidyl-peptidase iv inhibitors. Synonyms: BMS-477118; BMS 477118; BMS477118; Onglyza. Grades: 0.98. CAS No. 361442-04-8. Molecular formula: C18H25N3O2. Mole weight: 315.417. |  |
| Saxagliptin. | Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. Group: Biochemicals. Grades: Highly Purified. CAS No. 361442-04-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Saxagliptin Cyclic Amidine Impurity | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one. Grades: > 95%. CAS No. 1350800-76-8. Molecular formula: C18H25N3O2. Mole weight: 315.42. | |
| Saxagliptin hydrate | Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118 hydrate. CAS No. 945667-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10285A. | |
| Saxagliptin hydrochloride | Saxagliptin is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP-4). It has been approved for the treatment of type 2 diabetes. It was shown to prevent the inactivation of the incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide, thus promoting insulin secretion. Synonyms: Saxagliptin HCl; BMS-477118; (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride. Grades: ≥98%. CAS No. 709031-78-7. Molecular formula: C18H25N3O2·HCl. Mole weight: 351.9. | |
| Saxagliptin hydrochloride | Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118 hydrochloride. CAS No. 709031-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16448. | |
| Saxagliptin Impurity 1 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C17H27NO5. Mole weight: 325.41. | |
| Saxagliptin Impurity 10 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C11H18N2O3. Mole weight: 226.28. | |
| Saxagliptin Impurity 11 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C11H18N2O3. Mole weight: 226.28. | |
| Saxagliptin Impurity 12 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (S)-Boc-2-carbamoyl-2,3-dihydro-1H-pyrrole. Grades: > 95%. CAS No. 709031-38-9. Molecular formula: C10H16N2O3. Mole weight: 212.25. | |
| Saxagliptin Impurity 13 | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Grades: > 95%. Molecular formula: C12H20N2O4. Mole weight: 256.3. | |
| Saxagliptin Impurity 14 | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Synonyms: (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid; (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid. Grades: > 95%. CAS No. 197142-36-2. Molecular formula: C11H17NO4. Mole weight: 227.26. | |
| Saxagliptin Impurity 15 | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Synonyms: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo [3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carboxamide; 3-Descarbonitrile 3-Acetamido Saxagliptin. Grades: > 95%. CAS No. 1496712-39-0. Molecular formula: C18H27N3O3. Mole weight: 333.43. | |
| Saxagliptin Impurity 16 | Cas No. 709031-43-6. | |
| Saxagliptin Impurity 17 | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Synonyms: (1S,3S,5S)-2-((S)-2-Amino-2-((1s,3R,5S,7R)-4-oxoadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 3-Deshydroxy 3-Keto Saxagliptin. Grades: > 95%. Molecular formula: C18H23N3O2. Mole weight: 313.4. | |
| Saxagliptin Impurity 2 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: Saxagliptin IMpurity 2. Grades: > 95%. Molecular formula: C6H10N2O. Mole weight: 126.16. | |
| Saxagliptin Impurity 29 | Saxagliptin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334321-39-9. Molecular formula: C17H27NO5. Mole weight: 325.41. Catalog: APB1334321399. | |
| Saxagliptin Impurity 3 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C18H25N3O2. Mole weight: 315.42. | |
| Saxagliptin Impurity 4 (Deoxy Saxagliptin) | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C18H25N3O. HCl. Mole weight: 335.88. | |
| Saxagliptin Impurity 57 | Saxagliptin Impurity 57. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125347-83-3. Molecular formula: C12H21NO4. Mole weight: 243.3. Catalog: APB125347833. | |
| Saxagliptin Impurity 59 | Saxagliptin Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1091626-35-5. Molecular formula: C12H19NO4. Mole weight: 241.29. Catalog: APB1091626355. | |
| Saxagliptin Impurity 5 (Epoxy saxaglliptin) | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C18H23N3O2. HCl. Mole weight: 349.86. | |
| Saxagliptin Impurity 6 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (S)-2-((tert-Butoxycarbonyl)amino)-2-((1r,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)acetic Acid; (αS)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-3,5-dihydroxytricyclo[3.3.1.13,7]decane-1-acetic Acid. Grades: > 95%. CAS No. 681282-72-4. Molecular formula: C17H27NO6. Mole weight: 341.41. | |
| Saxagliptin Impurity 63 | Saxagliptin Impurity 63. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102502-64-7. Molecular formula: C12H20ClNO2. Mole weight: 245.75. Catalog: APB102502647. | |
| Saxagliptin Impurity 65 | Saxagliptin Impurity 65. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1058660-48-2. Molecular formula: C12H19NO3. Mole weight: 225.29. Catalog: APB1058660482. | |
| Saxagliptin Impurity 7 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (1aS,4S,6aR,7aS)-Hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione. Grades: > 95%. CAS No. 1350800-77-9. Molecular formula: C18H24N2O3. Mole weight: 316.4. | |
| Saxagliptin Impurity 8 (N-Formyl Saxagliptin) | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C19H25N3O3. Mole weight: 343.43. | |
| Saxagliptin Impurity 9 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Grades: > 95%. Molecular formula: C11H18N2O3. Mole weight: 226.28. | |
| Saxagliptin Keto Impurity | An impurity of Saxagliptin. Saxagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) used as a hypoglycemic drug. It was approved to treat type 2 diabetes. Synonyms: (1S,3S,5S)-2-((R)-2-amino-2-((1s,3R,5S,7S)-4-oxoadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Grades: 95%. Molecular formula: C18H23N3O2. Mole weight: 313.4. | |
| Saxagliptin monohydrate | Saxagliptin hydrate is a selective and reversible DPP4 inhibitor. It demonstrates greater specificity for DPP4 than for either the DPP8 or DPP9 enzymes. It reduces the degradation of the incretin hormone glucagon-like peptide-1, thereby enhancing its actions, and is associated with improved β-cell function and suppression of glucagon secretion. Synonyms: BMS-477118 hydrate; BMS 477118 hydrate; BMS477118 hydrate; Onglyza hydrate. Grades: >98%. CAS No. 945667-22-1. Molecular formula: C18H27N3O3. Mole weight: 333.43. | |
| Saxagliptin O- β-D-glucuronide | Saxagliptin O- β-D-glucuronide. Group: Biochemicals. Alternative Names: (2S,3S,5R,6S)-6-(((1R,3S,5R,7S)-3-((S)-1-Amino-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)adamantan-1-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grades: Highly Purified. CAS No. 1155849-58-3. Pack Sizes: 500ug. Molecular Formula: C24H33N3O8, Molecular Weight: 491.53. US Biological Life Sciences. | Worldwide |
| Saxagliptin O-Sulfate | Saxagliptin O-Sulfate. Group: Biochemicals. Alternative Names: (1S, 3S, 5S)-2-[(2S)-2-Amino-2-[3-(sulfooxy)tricyclo[3. 3. 1. 13, 7]dec-1-yl]acetyl]-2-Azabicyclo[3. 1. 0]hexane-3-carbonitrile. Grades: Highly Purified. CAS No. 1429782-94-4. Pack Sizes: 500ug. Molecular Formula: C18H25N3O5S, Molecular Weight: 395.47. US Biological Life Sciences. | Worldwide |
| Sazetidine A Dihydrochloride | Sazetidine A Hydrochloride is an α4 β2 nicotinic receptor desensitizing agent that exhibits analgesic properties. Sazetidine A Hydrochloride may be used to develop treatments and therapies that aid smoking cessation. Group: Biochemicals. Alternative Names: 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol dihydrochloride. Grades: Highly Purified. CAS No. 1197329-42-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 333.25. US Biological Life Sciences. | Worldwide |
| Sazetidine A hydrochloride | Sazetidine A hydrochloride is an α4β2 nicotinic acetylcholine receptor ligand (Ki = 0.26 and 54 nM at α4β2 and α3β4 receptors, respectively), displaying analgesic activity in vivo. Sazetidine A hydrochloride may act as a silent desensitizer or an agonist. Synonyms: 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol hydrochloride. Grades: ≥98% by HPLC. CAS No. 1197329-42-2. Molecular formula: C15H20N2O2.HCl. Mole weight: 296.797. | |
| SB1317 | SB1317 is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. It dose-dependently inhibits signaling pathways downstream of CDKs, JAK2 and FLT3 in cancer cells with the main targets being CDKs. SB1317 is anti-proliferative in a broad range of tumor cell lines, inducing G1 cell cycle arrest and apoptosis. In vivo, SB1317 exhibits favorable pharmacokinetics after oral dosing in xenograft models and accumulates in tumor tissues, inducing an effective blockade of both CDK and STAT signaling. SB1317 induces tumor regression after oral dosing on both daily and intermittent schedules in a murine model of mutant-FLT3 leukemia (MV4-11) and prolongs survival in a disseminated AML model with wild-type FLT3 and JAK2 (HL-60). SB1317 is active in various models of leukemia and provide a rationale for the ongoing clinical evaluation of TG02 in patients with advanced leukemias. Synonyms: TG02; TG 02; TG-02; SB1317 (Double bond E); TG02 (Double bond E). Grades: ≥98%. CAS No. 1204918-72-8. Molecular formula: C23H24N4O. Mole weight: 372.46. | |
| SB-200646A | SB-200646A is the first selective 5-HT 2B/2C over 5-HT 2A receptor antagonist with pK i values of 7.5, 6.9 and 5.2 for 5-HT 2B , 5-HT 2C and 5-HT 2A , respectively. SB-200646A is orally active and has electrophysiological and anxiolytic properties in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143797-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103129. | |
| SB 200646 hydrochloride | SB 200646 hydrochloride is an orally bioactive 5-HT2C/2B receptor antagonist displaying selectivity over 5-HT1A. Synonyms: SB 200646 hydrochloride; SB200646 hydrochloride; SB-200646 hydrochloride; N-(1-Methyl-1H-indol-5-yl)-N'-3-pyridinylurea; 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea hydrochloride. Grades: ≥98% by HPLC. CAS No. 143797-62-0. Molecular formula: C15H14N4O.HCl. Mole weight: 302.76. | |
| SB202190 | SB202190, also named FHPI, under the IUPAC name 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one, is a pyridinyl imidazole that selectively inhibits the p38α and β isoforms. IC50=50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively. Uses: A highly selective, potent and cell-permeable inhibitor of p38 map kinase(ic50 = 50 and 100 nm at sapk2a/p38 and sapk2b/p38β2) respectively). Synonyms: 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole; SB 202190; SB-202190; SB202190; SB 202190; 152121-30-7; SB-202190; SB202190; FHPI; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole; CHEBI:79090; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole; SB 202190, Immobilized; InSolution SB 202190; IN1110; IN1113; MFCD00941964; 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole; 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol; 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol; 4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol; C20H14FN3O; SB202190 (FHPI); SB202190, 152121-30-7; Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-i.. Grades: >98%. CAS No. 152121-30-7. Molecular formula: C20H14FN3O. Mole weight: 331.34. | |
| SB 202190 | SB 202190 is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits [1] [2]. SB202190 induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152121-30-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-10295. | |
| SB 202190 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 202190 | Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Group: Biochemicals. Alternative Names: 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol. Grades: Highly Purified. CAS No. 152121-30-7. Pack Sizes: 5mg. Molecular Formula: C20H14FN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 - CAS 152121-30-7 | SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38? (Ki = 16 nM; IC?? = 350 nM). Group: Fluorescence/luminescence spectroscopy. | |
| SB202190 (FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole) | Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Group: Biochemicals. Alternative Names: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Grades: Highly Purified. CAS No. 152121-30-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H14FN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 hydrochloride | SB 202190 hydrochloride. Group: Biochemicals. Alternative Names: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride. Grades: Highly Purified. CAS No. 350228-36-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C20H15ClFN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 hydrochloride | SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 hydrochloride has anti-cancer activity [1] [2]. SB202190 hydrochloride induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350228-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10295A. | |
| SB 202190 hydrochloride | SB 202190 is a potent, selective, and cell-permeable inhibitor of p38 MAP kinases, effective against p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. It inhibits p38 MAP kinases, resulting in blockade of tumor necrosis factor alpha (TNF-alpha) and interleukin-1beta (IL-1beta) production in monocytes. Synonyms: SB 202190 HCl; 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol hydrochloride. Grades: ≥98%. CAS No. 350228-36-3. Molecular formula: C20H14FN3O·HCl. Mole weight: 367.8. | |
| SB 202190, Hydrochloride - CAS 350228-36-3 | A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190. Group: Fluorescence/luminescence spectroscopy. | |
| SB 202190 monohydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 202474 | SB 202474 is an analog of SB 202190 and SB 203580, which are inhibitors of the MAP kinases p38α and p38&beta. SB 202474 has been used as a negative control in studies of p38 inhibition. Synonyms: SB-202474; SB202474; 4-[5-ethyl-2-(4-methoxyphenyl)-1H-imidazol-4-yl]pyridine. Grades: ≥97%. CAS No. 172747-50-1. Molecular formula: C17H17N3O. Mole weight: 279.3. | |
| SB 203186 hydrochloride | SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist with high affinity for human atrial 5-HT4 receptors. Synonyms: SB 203186 HCl; SB 203186 HCl; SB203186; SB-203186. 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride. Grades: ≥99% by HPLC. CAS No. 207572-69-8. Molecular formula: C16H20N2O2.HCl. Mole weight: 308.81. | |
| SB-203207 | SB-203207 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203207; SB203207. Molecular formula: C19H31N5O8S. Mole weight: 489.5. | |
| SB-203208 | SB-203208 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203208; SB203208. Molecular formula: C29H42N6O9S. Mole weight: 650.7. | |
| SB203580 | Cas No. 152121-47-6. | |
| SB 203580 | SB 203580 Inhibitor. Uses: Scientific use. Product Category: T1764. CAS No. 152121-47-6. |  |
| SB 203580 | solid, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB-203580 | SB 203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM. Uses: Enzyme inhibitors. Synonyms: SB203580; SB203580; SB 203580. Grades: >98%. CAS No. 152121-47-6. Molecular formula: C21H16FN3OS. Mole weight: 377.437. | |
| SB 203580 - CAS 152121-47-6 | SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC?? = 34 nM in vitro, 600 nM in cells). Group: Fluorescence/luminescence spectroscopy. | |
| SB 203580 hydrochloride | SB 203580 hydrochloride is a water-soluble form of the potent MAP kinase inhibitor SB 203580 with IC50 values of 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. It was shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. Synonyms: 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole hydrochloride. Grades: >98%. CAS No. 869185-85-3. Molecular formula: C21H17FN3OSCl. Mole weight: 413.9. | |
| SB 203580, Hydrochloride - CAS 869185-85-3 | SB 203580, Hydrochloride, CAS 869185-85-3, is a water-soluble form of SB 203580. A highly potent, selective, ATP-competitive inhibitor of p38 MAP Kinase (IC?? = 34 nM in vitro, 600 nM in cells). Group: Fluorescence/luminescence spectroscopy. | |
| SB 203580 Hydrochloride Salt | SB 203580 Hydrochloride Salt. Group: Biochemicals. Alternative Names: 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine; hydrochloride; SB203580 hydrochloride; SCHEMBL4890447; HY-10256A. Grades: Highly Purified. CAS No. 869185-85-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C21 H16 FN 3 , Molecular Weight: 413.9. US Biological Life Sciences. | Worldwide |
| SB 204070 | SB 204070 is a potent and selective 5-HT4 receptor antagonist (pIC50 = 10.1), displaying >5000-fold selectivity over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C, and 5-HT3 receptors. SB 204070 exhibits anxiolytic activity upon systemic administration in vivo. Uses: Serotonin antagonists. Synonyms: 1,4-Benzodioxin-5-carboxylic acid, 8-amino-7-chloro-2,3-dihydro-, (1-butyl-4-piperidinyl)methyl ester; (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-carboxylate; (1-Butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate; SB204070; SB-204070; (1-Butylpiperidin-4-yl)methyl 8-amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate. Grades: ≥95%. CAS No. 148702-58-3. Molecular formula: C19H27ClN2O4. Mole weight: 382.88. | |
| SB-204070 hydrochloride | solid, ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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