A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC 50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301836-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10431.
SB-431542 (GMP)
SB-431542 (GMP) is SB-431542 (HY-10431) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SB-431542 is a TGF-? receptor kinase inhibitor (TRKI) in SMAD signaling[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301836-41-9. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-10431G.
SB-431542 (Standard) is the analytical standard of SB-431542. SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC 50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301836-41-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-10431R.
SB-505124 is a selective inhibitor of TGF-? Receptor type I receptors (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6. Uses: Scientific research. Group: Signaling pathways. CAS No. 694433-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13521.
SB 525334 (SB-525334, 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline). Group: Biochemicals. Grades: Highly Purified. CAS No. 356559-20-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H21N5, Molecular Weight: 343.4. US Biological Life Sciences.
Worldwide
SB-590885
SB-590885 is a potent B-Raf inhibitor with a K i of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 405554-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10966.
SB-612111 hydrochloride hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 hydrochloride exhibits selectivity for ?-,??- and??-receptors with Ki values of?57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model[1].. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18618A.
SB-633825
SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956613-01-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108333.
SB-649868
SB-649868 is a potent and selective orally active orexin ( OX ) 1 and OX 2 receptor antagonist ( pK i =9.4 and 9.5 at the OX 1 and OX 2 receptor, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK649868. CAS No. 380899-24-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10806.
SB-674042 is a potent and selective non-peptide orexin OX 1 receptor antagonist (K d =5.03 nM), exhibits 100-fold selectivity for OX 1 over OX 2 receptors with IC 50 values of 3.76 nM and 531 nM, respectively [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 483313-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10898.
SB-699551
SB-699551 is a potent and selective 5-HT5A antagonist with a K i value of 5.1 μM. SB-699551 increases the phosphorylation levels of CREB and ATF1 , and decreases the phosphorylation levels of AKT , PRAS40 , P70S6K , FOXO1 , and S6RP. SB-699551 improves drug-induced cognitive deficits. SB-699551 improves social withdrawal and forgetfulness. SB-699551 inhibits breast cancer. Uses: Scientific research. Group: Signaling pathways. CAS No. 864741-95-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-103100.
A selective, brain penetrant, 5-HT5A receptor antagonis (pKi = 8.2). Competitively antagonised 5-HT-stimulated [35S]GTP-gamma-S binding to membranes from human embryonic kidney (HEK293) cells transiently expressing the guinea pig 5-HT5A receptor (pA2 8.1 ± 0.1) and displayed 100-fold selectivity versus the serotonin transporter and those 5-HT receptor subtypes (5-HT1A/B/D, 5-HT2A/C and 5-5-HT7). Group: Biochemicals. Grades: Highly Purified. CAS No. 791789-61-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O·2HCl. US Biological Life Sciences.
Worldwide
SB-705498
SB-705498. Group: Biochemicals. Grades: Highly Purified. CAS No. 501951-42-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
SB-743921 hydrochloride
SB-743921 hydrochloride is a potent inhibitor of the mitotic kinesin KSP (Eg5) , with a K i of 0.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 940929-33-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12069.
SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1781882-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110313.
SB-772077B dihydrochloride
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase (ROCK) inhibitor with IC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 607373-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108518.
SBA-15
SBA-15. Group: Sba-15. CAS No. 12173-28-3. Pack Sizes: 1 kg.
SBA-15 Molecular Sieve
Transparent to gray, odorless powder. Irritating to the skin and eyes on contact. Inhalation will cause irritation in the respiratory tract. [Note: Amorphous silica is the non-crystalline form of SiO2.];PelletsLargeCrystals, OtherSolid, Liquid;DryPowder; Liquid;DryPowder; OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals;DryPowder; OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, OtherSolid, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, PelletsLargeCrystals, OtherSolid; DryPowder, PelletsLargeCrystals, WetSolid; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid; WetSolid, Liquid;PelletsLargeCrystals;White, fluffy powder or granules. Hygroscopic;Solid;FINE WHITE POWDER.;COLOURLESS OR WHITE CRYSTALS.;COLOURLESS WHITE CRYSTALS.;COLOURLESS OR WHITE CRYSTALS.;Solid;Transparent to gray, odorless powder. [Note: Amorphous silica is the non-crystalline form of SiO2.]. Group: Molecular sieve. CAS No. 7631-86-9. Product ID: dioxosilane. Molecular formula: 60.084g/mol. Mole weight: (SiO2)n; SiO2; SiO2; SiO2; SiO2; SiO2; O2Si. O=[Si]=O. InChI=1S/O2Si/c1-3-2. VYPSYNLAJGMNEJ-UHFFFAOYSA-N.
sBADA is a potent green fluorescent dye. sBADA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA is used to label peptidoglycans in bacterial cell walls in situ. (λ ex =490 nm, λ em =510 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2376838-11-6. Pack Sizes: 1 mg. Product ID: HY-D1690A.
SBD-1 is an antibacterial peptide isolated from Ov is aries. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Beta-defensin 1; BD-1; Asn-Arg-Leu-Ser-Cys-His-Arg-Asn-Lys-Gly-Val-Cys-Val-Pro-Ser-Arg-Cys-Pro-Arg-His-Met-Arg-Gln-Ile-Gly-Thr-Cys-Arg-Gly-Pro-Pro-Val-Lys-Cys-Cys-Arg-Lys-Lys. Molecular formula: C195H342N78O50S7. Mole weight: 4803.77.
SBD-F
SBD-F. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Fluorobenzofurazan-4-sulfonicacid ammonium salt. Product Category: Other Fluorophores. Appearance: Yellow powder. CAS No. 84806-27-9. Molecular formula: C6H6FN3O4S. Mole weight: 235.19. Purity: 98%+. IUPACName: Azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonicacid. Canonical SMILES: C1=C(C2=NON=C2C(=C1)S(=O)(=O)O)F.N. Product ID: ACM84806279-1. Alfa Chemistry  ISO 9001:2015 Certified. Categories: SBD Freeway.
SBE-13 HCl
SBE-13 is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μ M for PLK1, PLK3 and PLK2 respectively). Uses: Designed for use in research and industrial production. Additional or Alternative Names: SBE13; SBE 13; SBE13; SBE-13 HCl. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 1052532-15-6. Molecular formula: C24H27ClN2O4. Mole weight: 442.94. Purity: >98%. IUPACName: N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride. Canonical SMILES: COC1=CC=C(CCNCC2=CC=C(OCC3=CC=C(Cl)N=C3)C(OC)=C2)C=C1OC.[H]Cl. Product ID: ACM1052532156. Alfa Chemistry  ISO 9001:2015 Certified. Categories: SBE13 hydrochloride.
SBE 13 hydrochloride
SBE 13 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1052532-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
S-Benzyl-D-cysteine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
S-benzyl-DL-Cysteine-[1-13C]
S-benzyl-DL-Cysteine-[1-13C] is a labelled S-benzyl-DL-Cysteine, which is a derivative of cysteine. Grade: 98% by HPLC; 99% atom 13C. CAS No. 77284-35-6. Molecular formula: C9[13C]H13NO2S. Mole weight: 212.27.
S-Benzyl-DL-cysteine-[2,3,3-d3]
S-Benzyl-DL-cysteine-[2,3,3-d3] is a labelled S-Benzylcysteine, which is a derivative of cysteine. Grade: 95% by HPLC; 98% atom D. CAS No. 51494-04-3. Molecular formula: C10H10D3NO2S. Mole weight: 214.3.
S-Benzyl-DL-cysteine-2,3,3-d3
S-Benzyl-DL-cysteine-2,3,3-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-3-benzylsulfanyl-2,3,3-trideuteriopropanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 51494-04-3. Molecular formula: C10H10D3NO2S. Mole weight: 214.3. Purity: 98 atom % D. IUPACName: 2-amino-3-benzylsulfanyl-2,3,3-trideuteriopropanoic acid. Canonical SMILES: [2H]C([2H])(C([2H])(C(=O)O)N)SCC1=CC=CC=C1. Product ID: ACM51494043. Alfa Chemistry  ISO 9001:2015 Certified.
S-Benzyl-L-cysteine. Group: Biochemicals. Alternative Names: L-Cys(Bzl)-OH; (R)-2-Amino-3-benzylsulfanyl-propionic acid. Grades: Highly Purified. CAS No. 3054-1-1. Pack Sizes: 100g, 250g. US Biological Life Sciences.
Worldwide
S-benzyl-L-Cysteine-[3-13C]
S-benzyl-L-Cysteine-[3-13C] is a labelled S-benzyl-L-Cysteine, which is a derivative of cysteine. Grade: 98% by HPLC; 99% atom 13C. CAS No. 79761-09-4. Molecular formula: C4[13C]H9NO4. Mole weight: 212.27.
S-Benzyl-L-cysteine 4-nitroanilide
S-Benzyl-L-cysteine 4-nitroanilide. Group: Biochemicals. Alternative Names: L-Cys(Bzl)-pNA. Grades: Highly Purified. CAS No. 7436-62-6. Pack Sizes: 1g, 2g. US Biological Life Sciences.
Worldwide
S-Benzyl-L-cysteine 4-nitroanilide
A substrate for cystyl aminopeptidase (oxytocinase). Synonyms: L-Cys(Bzl)-pNA. Grade: ≥ 98% (TLC). CAS No. 7436-62-6. Molecular formula: C16H17N3O3S. Mole weight: 331.43.
S-Benzyl-L-cysteine 4-nitroanilide 98+% (TLC)
S-Benzyl-L-cysteine 4-nitroanilide 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 7436-62-6. Pack Sizes: 250mg, 1g, 2.5g. US Biological Life Sciences.