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| Product | Description | |
|---|---|---|
| SB239063 | SB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide-stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin-1 and tumor necrosis factor-alpha production. SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Uses: Protein kinase inhibitors. Synonyms: SB-239063; SB 239063. Grades: 0.98. CAS No. 193551-21-2. Molecular formula: C20H21FN4O2. Mole weight: 368.412. |  |
| SB 239063 | SB 239063 is a potent, selective and orally active p38 MAPK inhibitor, exhibits an IC50 of 44 nM for recombinant purified human p38?, with equipotent inhibitory activity against p38? and p38?. SB 239063 has no effect on p38? or p38?. With anti-asthma activity and also be used to enhance memory which is impaired due to aging or medical conditions, such as, AD[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193551-21-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-11068. |  |
| SB 239063 | >98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| SB 239063 - CAS 798558-40-4 | A potent, cell-permeable, reversible, and ATP-competitive inhibitor of the ?- and ?-isoforms (IC?? = 44 nM), but not the ?- or ?-isoform (IC?? > 100 μM), of MAP kinase p38. Group: Fluorescence/luminescence spectroscopy. | |
| SB 242084 | SB 242084 is a brain-penetrant antagonist of 5-HT2C receptor which exhibits 158-fold selectivity for 5-HT2C (pKi= 9.0) over 5-HT2A receptor (pKi= 6.1-6.8) and 100-fold selectivity over 5-HT2B receptor (pKi= 6.8-7.0). Synonyms: SB 242084; SB242084; SB-242084; 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;dihydrochloride181632-25-76-Chloro-5-methyl-N-(6-((2-methylpyridin-3-yl)oxy)pyridin-3-yl)indoline-1-carboxamide dihydrochlorideSB 242084 (hydrochloride)6-chl. CAS No. 181632-25-7. Molecular formula: C21H19ClN4O2. Mole weight: 394.85. | |
| SB-242084 HCl salt | SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor. It can increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. Synonyms: SB-242084; SB 242084; SB242084; SB-242084 HCl. Grades: 98%. CAS No. 1049747-87-6. Molecular formula: C21H21Cl3N4O2. Mole weight: 467.78. | |
| SB 242084 hydrochloride | SB 242084 hydrochloride is a selective and brain penetrant 5-HT2C receptor antagonist with over 100-fold selectivity versus a range of other 5-HT, dopamine and adrenergic receptors. Synonyms: SB 242084 hydrochloride; SB242084 hydrochloride; SB-242084 hydrochloride; 6-chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide hydrochloride. Grades: 99%. CAS No. 1260505-34-7. Molecular formula: C21H19ClN4O2.HCl. Mole weight: 431.32. | |
| SB 242084 Hydrochloride (5-HT2C Receptor Antagonist, SB 242084 Hydrochloride, SB-242084 Hydrochloride, SB242084 Hydrochloride) | A selective, brain-penetrant 5-HT2C receptor antagonist (pKi 8.2-9.0 ), with some effects on the 5-HT2B receptor (pKi 6.8-7.0) and 5-HT2A receptor (pKi 6.1-6.8). SB 242084 has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242,084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines. In vivo (ocular) IC50 values reported at 2.08uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 181632-25-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| SB 242235 | SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC 50 of 1.0?μM in primary human chondrocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193746-75-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18306. | |
| SB-242235 | SB-242235 is a potent and selective p38 MAP kinase inhibitor with IC50 of 1.0 uM. Synonyms: SB-242235; SB242235. Grades: 0.99. CAS No. 193746-75-7. Molecular formula: C18H17N5O3. Mole weight: 353.401. | |
| SB 243213 dihydrochloride | SB 243213 dihydrochloride is a 5-HT2C inverse agonist (pKb = 9.8) with selectivity over other 5-HT2 subtypes (pKi = 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively). SB 243213 exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes. SB 243213 shows anxiolytic activity in rat models. Synonyms: SB 243213 dihydrochloride; SB 243213 dihydrochloride; SB 243213 dihydrochloride; 2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-Indole-1-carboxamide dihydrochloride. Grades: ≥99% by HPLC. CAS No. 200940-23-4. Molecular formula: C22H19F3N4O2.2HCl. Mole weight: 501.33. | |
| SB 243213 dihydrochloride | SB 243213 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 200940-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB-253514 | SB-253514 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 253514; SB253514. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
| SB-258585 dihydrochloride | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| SB 258585 hydrochloride | SB 258585 hydrochloride is a potent and selective 5-HT6 receptor antagonist (pKi = 8.6) with > 160-fold selectivity over other 5-HT receptor subtypes, dopamine and α-adrenergic receptors. Synonyms: SB 258585 hydrochloride; SB258585 hydrochloride; SB-258585 hydrochloride; 4-Iodo-N-[4-methoxy-3- (4-methyl-1-piperazinyl) phenyl]benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1216468-02-8. Molecular formula: C18H22IN3O3S.HCl. Mole weight: 523.82. | |
| SB-258585 hydrochloride | SB-258585 is a high affinity ligand for the 5-HT 6 receptor. SB-258585 binds highly to a single receptor population in a human cell line that recombines 5-HT 6 receptors. SB-258585 can be used to label recombinant and natural 5-HT 6 receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216468-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103141. | |
| SB-258719 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 258719 hydrochloride | SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist, displaying > 100-fold selectivity over a range of other receptors. SB 258719 shows inverse action on hypothermic effect of 5-CT in mice following i.p. administration. Synonyms: SB 258719 hydrochloride; SB258719 hydrochloride; SB-258719 hydrochloride; 3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride; N,3-dimethyl-N-[(2R)-4-(4-methylpiperidin-1-yl)butan-2-yl]benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1217674-10-6. Molecular formula: C18H30N2O2S.HCl. Mole weight: 374.97. | |
| SB 258741 hydrochloride | SB 258741 hydrochloride is a serotonin 5-HT7 antagonist. Synonyms: SB 258741 hydrochloride; SB-258741 hydrochloride; SB258741 hydrochloride. Grades: 99%. CAS No. 201038-58-6. Molecular formula: C19H30N2O2S.HCl. Mole weight: 386.98. | |
| SB265610 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 265610 | SB 265610 is a potent CXCR2 antagonist. Synonyms: SB-265610; SB 265610; SB265610. 1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea; N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea. CAS No. 211096-49-0. Molecular formula: C14H9BrN6O. Mole weight: 357.16. | |
| SB-265610 | SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SB-265610; SB 265610; SB265610. Product Category: Antagonists. Appearance: Solid powder. CAS No. 211096-49-0. Molecular formula: C14H9BrN6O. Mole weight: 357.17. Purity: >98%. IUPACName: N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea. Canonical SMILES: O=C(NC1=C2N=NNC2=C(C#N)C=C1)NC3=CC=CC=C3Br. Product ID: ACM211096490. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SB 268262 | SB 268262 is a selective and non-peptide calcitonin gene-related peptide (CGRP1) receptor antagonist. SB 268262 inhibits [125I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes (IC50 = 0.24 and 0.83 nM, respectively). Synonyms: SB 268262; SB-268262; SB268262; N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide. Grades: ≥99% by HPLC. CAS No. 217438-17-0. Molecular formula: C18H15N3O4S2. Mole weight: 401.46. | |
| SB-268262 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB269652 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB269652 | SB269652, an allosteric modulator of D2R, consists of a tetrahydroisoquinoline pharmacophore bound in the OBS and an indole-2-carboxamide moiety bound in a SBP between TM2 and TM7. SB269652 is the first drug-like allosteric modulator of the dopamine D2 re. Uses: Dopamine d2 receptor antagonists. Synonyms: N-[4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide1H-indole-2-carboxylic acid (4-(2-(cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)cyclohexyl)amideSB269652; SB-269652; SB2 69652; SB269,652; SB-269,652; SB 269,652. CAS No. 215802-15-6. Molecular formula: C27H30N4O. Mole weight: 426.55. | |
| SB-269970 | SB-269970 is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pK i of 8.3. SB-269970 exhibits >50-fold selectivity against other 5-HT receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201038-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370. | |
| SB-269970 | SB-269970 is a selective 5-HT7 receptor antagonist (pKi of 8.3) with >50-fold selectivity against other receptors, on amphetamine and ketamine-induced hyperactivity and prepulse inhibition (PPI) deficits. Synonyms: 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenolSB 269970; SB269970SB-269970. Grades: >98 %. CAS No. 201038-74-6. Molecular formula: C18H28N2O3S. Mole weight: 352.49. | |
| SB-269970 hydrochloride | SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors. Synonyms: SB-269970 hydrochloride; SB 269970 hydrochloride; SB269970 hydrochloride. Grades: >98%. CAS No. 261901-57-9. Molecular formula: C18H28N2O3S.HCl. Mole weight: 388.95. | |
| SB-269970 hydrochloride | powder, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB-269970 hydrochloride | SB-269970 hydrochloride is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pK i of 8.3. SB-269970 hydrochloride exhibits >50-fold selectivity against other 5-HT receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-269970A. CAS No. 261901-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370A. | |
| SB-269970 Hydrochloride (5-HT7 Serotonin Receptor Antagonist, SB-269970, SB 26,970, SB 26,970) | A selective 5-HT7 receptor antagonist. Extremely potent in vivo and in vitro. Chronic or acute (even single dose) administration of SB269970 induces functional desensitization of the 5-HT7 receptor system, which precedes changes in the receptor density. This mechanism may be responsible for the rapid antidepressant-like effect of the 5-HT7 antagonist in animal models. SB-269970 is an analogue of SB-258719 and has been shown to have at least 100 fold selectivity versus all other 5-HT receptor subtypes except the human 5-HT5A receptor (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B). Group: Biochemicals. Grades: Highly Purified. CAS No. 261901-57-9. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S·HCl. US Biological Life Sciences. | Worldwide |
| SB271046 | SB-271046 is found to be a competitive antagonist with a pA2 of 8.7 in the functional adenylyl cyclase assay which is in good agreement with its binding affinity. Synonyms: SB 271046; SB-271046; 5-Chloro-N-(4-methoxy-3-(1-piperazinyl)phenyl)-3-methylbenzo(b)thiophene-2-sulfonamide. Grades: >98%. CAS No. 209481-20-9. Molecular formula: C20H22ClN3O3S2. Mole weight: 451.99. | |
| SB-271046A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 271046 Hydrochloride | SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pK i of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC 50 =0.16 μM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 271046A. CAS No. 209481-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14336A. | |
| SB 271046 Hydrochloride | SB 271046 Hydrochloride is the hydrochloride salt form of SB 271046. SB 271046 is an orally-available and selective antagonist of the serotonin (5-hydroxytryptamine or 5-HT) receptor 5-HT6 with at least 100-fold selective for 5-HT6 (pKi = 9.02-8.92) over. Synonyms: 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-benzo[b]thiophene-2-sulfonamide Hydrochloride; SB 271046A. CAS No. 209481-24-3. Molecular formula: C20H23Cl2N3O3S2. Mole weight: 488.45. | |
| SB273005 | SB273005 inhibits human osteoclast-mediated bone resorption with IC50 of 11 nM.SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively. Synonyms: SB 273005; SB-273005; (S)-2-(8-(2-(6-(Methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid. Grades: >98%. CAS No. 205678-31-5. Molecular formula: C22H24F3N3O4. Mole weight: 451.44. | |
| SB-273005 | SB-273005 is an orally active non-peptide ?v?3 integrin antagonist with Ki values of 1.2 nM and 0.3 nM for ?v?3 and ?v?5, respectively. SB-273005 blocks the binding of integrins to the RGD sequence in the extracellular matrix. SB-273005 inhibits Rictor phosphorylation and reduces IL-10 secretion. SB-273005 inhibits inflammation, prevents bone loss, regulates vascular smooth muscle function, and reverses pregnancy-induced immune deviation. SB-273005 can be used in the study of rheumatoid arthritis, osteoporosis, and aneurysms. [1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 205678-31-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19307. | |
| Sb-277011 | Sb-277011 is a novel, high-anity and selective dopamine D3 receptor antagonist that may have potential in treating the negative symptoms of schizophrenia. pKi: 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively. Synonyms: N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide SB 277011 SB 277011-A SB-277011 SB-277011-A trans-N-(4-(2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)cyclohexyl)-4-quinolinecarboxamide. CAS No. 215803-78-4. Molecular formula: C28H30N4O. Mole weight: 438.56. | |
| SB 277011A dihydrochloride | SB 277011A dihydrochloride is a selective and brain penetrating dopamine D3 receptor antagonist (pKi = 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B, respectively) with 100-fold selectivity over the hD2 receptor and over 66 other receptors. Synonyms: SB 277011A dihydrochloride; SB277011A dihydrochloride; SB-277011A dihydrochloride; N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1226917-67-4. Molecular formula: C28H30N4O.2HCl. Mole weight: 511.49. | |
| SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A) | A brain-penetrant, high-affinity, and selective dopamine D3 receptor antagonist. High affinity for the hD3 receptor (pKi = 7.95) with 100-fold selectivity over the hD2 receptor and over 66 other receptors, enzymes, and ion channels. Rat data shows that the compound is selective for the D3 receptor over certain serotonergic and cholinergic receptors at doses up to 56mg/kg and strong physiological response at 32mg/kg. Group: Biochemicals. Grades: Highly Purified. CAS No. 1226917-67-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| SB-277011-A hydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Sb 277011 hydrochloride | Sb 277011 hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SB 277011 Hydrochloride;N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- 4-quinolinecarboxaMide Hydrochloride;SB 277011A Hydrochloride;SB 277211 Hydrochloride;SB-277011-A hydrochloride hydrate. CAS No. 215804-67-4. Molecular formula: C28H30N4O. Mole weight: 438.564. Purity: 98%+. IUPACName: N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide. Canonical SMILES: C1CC(CCC1CCN2CCC3=C(C2)C=CC(=C3)C#N)NC(=O)C4=CC=NC5=CC=CC=C45. Product ID: ACM215804674. Alfa Chemistry ISO 9001:2015 Certified. | |
| SB 277011 hydrochloride | SB 277011 hydrochloride. Group: Biochemicals. Alternative Names: N-[trans-4-[2- (6-Cyano-3, 4-dihydro-2 (1H) -isoquinolinyl) ethyl]cyclohexyl]-4-quinolinecarboxamide hydrochloride; SB 277011A hydrochloride; SB 277211 hydrochloride. Grades: Highly Purified. CAS No. 215804-67-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H31ClN4O. US Biological Life Sciences. | Worldwide |
| SB-277011 hydrochloride | SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D 3 receptor (D 3 R) antagonist with K i values of 10.7 nM and 11.2 nM at rodent and human D 3 R, respectively. SB-277011 hydrochloride displays 80- to 100-fold selectivity over other dopamine receptors with pK i s of 8.0, 6.0, <5.2, and 5.9 for D3, D2, 5-HT 1B , and 5-HT 1D receptors, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-277011A hydrochloride. CAS No. 215804-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10847B. | |
| SB 290157 - CAS 1140525-25-2 | A non-peptide that acts as a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor (IC?? = 200 nM). Group: Fluorescence/luminescence spectroscopy. | |
| SB290157 trifluoroacetate | SB290157 trifluoroacetate is a potent and selective C3a receptor antagonist with an IC50 of 200 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1140525-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101502A. | |
| SB290157 trifluoroacetate | SB290157 trifluoroacetate is selective, high affinity, competitive C3a receptor antagonist (IC50 = 200 nM) suitable for use in animal models of inflammation. Synonyms: SB290157 trifluoroacetate; SB 290157 trifluoroacetate; SB-290157 trifluoroacetate; 5- (diaminomethylideneamino) -2-[[2- (2, 2-diphenylethoxy) acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid; IN1105. CAS No. 1140525-25-2. Molecular formula: C24H29F3N4O6. Mole weight: 526.51. | |
| SB290157 trifluoroacetate salt | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 297006 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 297006 | SB 297006. Group: Biochemicals. Grades: Purified. CAS No. 58816-69-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB 297006 | SB 297006 is a potent and selective CCR3 antagonist. Synonyms: 2,2',3,3,3',3'-Hexahydroxy-2,2'-biindan-1,1'-dione; Hydrindantin, anhydrous; 5950-69-6; NSC108697; SB 297006; SB297006; SB-297006; EINECS 227-713-1. CAS No. 58816-69-6. Molecular formula: C18H18N2O5. Mole weight: 342.35. | |
| SB-311009 | SB-311009 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 311009; SB311009. Molecular formula: C22H36N2O5. Mole weight: 408.5. | |
| SB-315021 | SB-315021 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 315021; SB315021. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
| SB 328437 | SB 328437 is a potent and selective CCR3 antagonist. Synonyms: methyl 2-naphthoylamino-3-(4-nitrophenyl)propionate; SB328437; SB 328437; SB-328437. CAS No. 247580-43-4. Molecular formula: C21H18N2O5. Mole weight: 378.38. | |
| SB 328437 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SB 328437 | SB 328437. Group: Biochemicals. Grades: Purified. CAS No. 247580-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB-328437 | SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC 50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 247580-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103363. | |
| SB-332235 | SB-332235 is a potent CXCR2 antagonist. Synonyms: 6-chloro-3-(3-(2,3-dichlorophenyl)ureido)-2-hydroxybenzenesulfonamide; SB-332235; SB 332235; SB332235. CAS No. 276702-15-9. Molecular formula: C13H10Cl3N3O4S. Mole weight: 410.66. | |
| SB 334867 | SB 334867. Group: Biochemicals. Alternative Names: N-(2-Methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-urea Hydrochloride. Grades: Highly Purified. CAS No. 249889-64-3. Pack Sizes: 10mg. Molecular Formula: C17H14ClN5O2, Molecular Weight: 355.78. US Biological Life Sciences. | Worldwide |
| SB-334867 | SB-334867, with sedative and anorectic effects, it is the first non-peptide selective antagonist of orexin receptor subtype OX1 (pKb= 7.2) with 50 -fold selectivity for OX1 over OX2 receptors. in vitro: inhibited the orexin-A (10 nM) and orexin-B (100 nM). Synonyms: 1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea hydrochloride SB 334867-A SB 334867A SB-334867 SB-334867-A SB-334867A SB3348. Grades: >99 %. CAS No. 249889-64-3. Molecular formula: C17H13N5O2. Mole weight: 319.32. | |
| SB-334867 | SB-334867 (SB 334867A) is an excellent,selective and blood - brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 ( pK b =7.4), 100-fold over 5-HT 2B , 5-HT 2C with pK i values of 5.4 and 5.3, respectively [1]. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 334867A. CAS No. 249889-64-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10895. | |
| SB-334867 free base | SB-334867 free base (SB334867A free base) is an excellent, selective and blood - brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 ( pK b =7.4), 100-fold over 5-HT 2B , 5-HT 2C with pK i values of 5.4 and 5.3, respectively [1]. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB334867A free base. CAS No. 792173-99-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10895A. | |
| SB-366791 | SB-366791 is a potent and selective vanilloid receptor ( VR1/TRPV1 ) antagonist ( IC 50 =5.7 nM). SB-366791 can be used for the research of inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 472981-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12245. | |
| SB-366791 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| SB-366791 | SB-366791 is a potent, and selective cinnamide TRPV1 antagonist (pA2 = 7.71 at hVR1) with IC50 of 5.7±1.2 nM. Uses: A potent, and selective cinnamide trpv1 antagonist. Synonyms: SB-366791; SB 366791; SB366791. N-(4-Methoxyphenyl)-4-chlorocinnamamide;3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide. Grades: ≥98%. CAS No. 472981-92-3. Molecular formula: C16H14ClNO2. Mole weight: 287.74. | |
| SB366791 (N-(3-Methoxyphenyl)-4-chlorocinnamide) | Potent and selective TRPV1 antagonist. Glutamatergic synaptic transmission inhibitor. Group: Biochemicals. Alternative Names: N-(3-Methoxyphenyl)-4-chlorocinnamide. Grades: Highly Purified. CAS No. 472981-92-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H14ClNO2, Molecular Weight: 287.8. US Biological Life Sciences. | Worldwide |
| SB 399885 hydrochloride | SB 399885 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 402713-81-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB 399885 hydrochloride | SB 399885 hydrochloride is a brain penetrating and orally active 5-HT6 antagonist, displaying > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi = 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors, respectively). Synonyms: SB 399885 hydrochloride; SB399885 hydrochloride; SB-399885 hydrochloride; N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 402713-81-9. Molecular formula: C18H21Cl2N3O4S.HCl. Mole weight: 482.81. | |
| SB-399885 hydrochloride | SB-399885 hydrochloride is a 5-HT 6 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 402713-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103099. | |
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