American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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SB 228357 Quick inquiry Where to buy Suppliers range | SB 228357 is a 5-HT2C/2B receptor antagonist (pKi = 7.0, 8.1 and 9.1 at 5-HT2A, 2B and 2C receptors, respectively) used in the treatment of irritable bowel syndrome (IBS). SB 228357 shows inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT2C receptor function. Uses: The treatment of irritable bowel syndrome (ibs). Synonyms: SB-228357; SB 228357; SB228357. N-[3-Fluoro-5-(3-pyrindyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide. Grades: ≥99% by HPLC. CAS No. 181629-93-6. Molecular formula: C22H17F4N3O2. Mole weight: 431.39. | |
SB239063 Quick inquiry Where to buy Suppliers range | SB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide-stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin-1 and tumor necrosis factor-alpha production. SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Uses: Protein kinase inhibitors. Synonyms: SB-239063; SB 239063. Grades: 0.98. CAS No. 193551-21-2. Molecular formula: C20H21FN4O2. Mole weight: 368.412. | |
SB 242084 Quick inquiry Where to buy Suppliers range | SB 242084 is a brain-penetrant antagonist of 5-HT2C receptor which exhibits 158-fold selectivity for 5-HT2C (pKi= 9.0) over 5-HT2A receptor (pKi= 6.1-6.8) and 100-fold selectivity over 5-HT2B receptor (pKi= 6.8-7.0). Synonyms: SB 242084; SB242084; SB-242084; 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;dihydrochloride181632-25-76-Chloro-5-methyl-N-(6-((2-methylpyridin-3-yl)oxy)pyridin-3-yl)indoline-1-carboxamide dihydrochlorideSB 242084 (hydrochloride)6-chl. CAS No. 181632-25-7. Molecular formula: C21H19ClN4O2. Mole weight: 394.85. | |
SB-242084 HCl salt Quick inquiry Where to buy Suppliers range | SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor. It can increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. Synonyms: SB-242084; SB 242084; SB242084; SB-242084 HCl. Grades: 98%. CAS No. 1049747-87-6. Molecular formula: C21H21Cl3N4O2. Mole weight: 467.78. | |
SB 242084 hydrochloride Quick inquiry Where to buy Suppliers range | SB 242084 hydrochloride is a selective and brain penetrant 5-HT2C receptor antagonist with over 100-fold selectivity versus a range of other 5-HT, dopamine and adrenergic receptors. Synonyms: SB 242084 hydrochloride; SB242084 hydrochloride; SB-242084 hydrochloride; 6-chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide hydrochloride. Grades: 99%. CAS No. 1260505-34-7. Molecular formula: C21H19ClN4O2.HCl. Mole weight: 431.32. | |
SB 242084 Hydrochloride (5-HT2C Receptor Antagonist, SB 242084 Hydrochloride, SB-242084 Hydrochloride, SB242084 Hydrochloride) Quick inquiry Where to buy Suppliers range | A selective, brain-penetrant 5-HT2C receptor antagonist (pKi 8.2-9.0 ), with some effects on the 5-HT2B receptor (pKi 6.8-7.0) and 5-HT2A receptor (pKi 6.1-6.8). SB 242084 has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242,084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines. In vivo (ocular) IC50 values reported at 2.08uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 181632-25-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
SB-242235 Quick inquiry Where to buy Suppliers range | SB-242235 is a potent and selective p38 MAP kinase inhibitor with IC50 of 1.0 uM. Synonyms: SB-242235; SB242235. Grades: 0.99. CAS No. 193746-75-7. Molecular formula: C18H17N5O3. Mole weight: 353.401. | |
SB 243213 dihydrochloride Quick inquiry Where to buy Suppliers range | SB 243213 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 200940-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
SB 243213 dihydrochloride Quick inquiry Where to buy Suppliers range | SB 243213 dihydrochloride is a 5-HT2C inverse agonist (pKb = 9.8) with selectivity over other 5-HT2 subtypes (pKi = 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively). SB 243213 exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes. SB 243213 shows anxiolytic activity in rat models. Synonyms: SB 243213 dihydrochloride; SB 243213 dihydrochloride; SB 243213 dihydrochloride; 2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-Indole-1-carboxamide dihydrochloride. Grades: ≥99% by HPLC. CAS No. 200940-23-4. Molecular formula: C22H19F3N4O2.2HCl. Mole weight: 501.33. | |
SB-253514 Quick inquiry Where to buy Suppliers range | SB-253514 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 253514; SB253514. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
SB-258585 dihydrochloride Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 10MG, 50MG. Mole weight: 560.28. Catalog: IAR4241613. Assay: ≥98% (HPLC). | |
SB 258585 hydrochloride Quick inquiry Where to buy Suppliers range | SB 258585 hydrochloride is a potent and selective 5-HT6 receptor antagonist (pKi = 8.6) with > 160-fold selectivity over other 5-HT receptor subtypes, dopamine and α-adrenergic receptors. Synonyms: SB 258585 hydrochloride; SB258585 hydrochloride; SB-258585 hydrochloride; 4-Iodo-N-[4-methoxy-3- (4-methyl-1-piperazinyl) phenyl]benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1216468-02-8. Molecular formula: C18H22IN3O3S.HCl. Mole weight: 523.82. | |
SB 258719 hydrochloride Quick inquiry Where to buy Suppliers range | SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist, displaying > 100-fold selectivity over a range of other receptors. SB 258719 shows inverse action on hypothermic effect of 5-CT in mice following i.p. administration. Synonyms: SB 258719 hydrochloride; SB258719 hydrochloride; SB-258719 hydrochloride; 3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride; N,3-dimethyl-N-[(2R)-4-(4-methylpiperidin-1-yl)butan-2-yl]benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1217674-10-6. Molecular formula: C18H30N2O2S.HCl. Mole weight: 374.97. | |
SB 258741 hydrochloride Quick inquiry Where to buy Suppliers range | SB 258741 hydrochloride is a serotonin 5-HT7 antagonist. Synonyms: SB 258741 hydrochloride; SB-258741 hydrochloride; SB258741 hydrochloride. Grades: 99%. CAS No. 201038-58-6. Molecular formula: C19H30N2O2S.HCl. Mole weight: 386.98. | |
SB 265610 Quick inquiry Where to buy Suppliers range | SB 265610 is a potent CXCR2 antagonist. Synonyms: SB-265610; SB 265610; SB265610. 1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea; N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea. CAS No. 211096-49-0. Molecular formula: C14H9BrN6O. Mole weight: 357.16. | |
SB 268262 Quick inquiry Where to buy Suppliers range | SB 268262 is a selective and non-peptide calcitonin gene-related peptide (CGRP1) receptor antagonist. SB 268262 inhibits [125I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes (IC50 = 0.24 and 0.83 nM, respectively). Synonyms: SB 268262; SB-268262; SB268262; N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide. Grades: ≥99% by HPLC. CAS No. 217438-17-0. Molecular formula: C18H15N3O4S2. Mole weight: 401.46. | |
SB269652 Quick inquiry Where to buy Suppliers range | SB269652, an allosteric modulator of D2R, consists of a tetrahydroisoquinoline pharmacophore bound in the OBS and an indole-2-carboxamide moiety bound in a SBP between TM2 and TM7. SB269652 is the first drug-like allosteric modulator of the dopamine D2 re. Uses: Dopamine d2 receptor antagonists. Synonyms: N-[4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide1H-indole-2-carboxylic acid (4-(2-(cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)cyclohexyl)amideSB269652; SB-269652; SB2 69652; SB269,652; SB-269,652; SB 269,652. CAS No. 215802-15-6. Molecular formula: C27H30N4O. Mole weight: 426.55. | |
SB-269970 Quick inquiry Where to buy Suppliers range | SB-269970 is a selective 5-HT7 receptor antagonist (pKi of 8.3) with >50-fold selectivity against other receptors, on amphetamine and ketamine-induced hyperactivity and prepulse inhibition (PPI) deficits. Synonyms: 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenolSB 269970; SB269970SB-269970. Grades: >98 %. CAS No. 201038-74-6. Molecular formula: C18H28N2O3S. Mole weight: 352.49. | |
SB-269970 hydrochloride Quick inquiry Where to buy Suppliers range | SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors. Synonyms: SB-269970 hydrochloride; SB 269970 hydrochloride; SB269970 hydrochloride. Grades: >98%. CAS No. 261901-57-9. Molecular formula: C18H28N2O3S.HCl. Mole weight: 388.95. | |
SB-269970 Hydrochloride (5-HT7 Serotonin Receptor Antagonist, SB-269970, SB 26,970, SB 26,970) Quick inquiry Where to buy Suppliers range | A selective 5-HT7 receptor antagonist. Extremely potent in vivo and in vitro. Chronic or acute (even single dose) administration of SB269970 induces functional desensitization of the 5-HT7 receptor system, which precedes changes in the receptor density. This mechanism may be responsible for the rapid antidepressant-like effect of the 5-HT7 antagonist in animal models. SB-269970 is an analogue of SB-258719 and has been shown to have at least 100 fold selectivity versus all other 5-HT receptor subtypes except the human 5-HT5A receptor (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B). Group: Biochemicals. Grades: Highly Purified. CAS No. 261901-57-9. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S·HCl. US Biological Life Sciences. | Worldwide |
SB271046 Quick inquiry Where to buy Suppliers range | SB-271046 is found to be a competitive antagonist with a pA2 of 8.7 in the functional adenylyl cyclase assay which is in good agreement with its binding affinity. Synonyms: SB 271046; SB-271046; 5-Chloro-N-(4-methoxy-3-(1-piperazinyl)phenyl)-3-methylbenzo(b)thiophene-2-sulfonamide. Grades: >98%. CAS No. 209481-20-9. Molecular formula: C20H22ClN3O3S2. Mole weight: 451.99. | |
SB 271046 Hydrochloride Quick inquiry Where to buy Suppliers range | SB 271046 Hydrochloride is the hydrochloride salt form of SB 271046. SB 271046 is an orally-available and selective antagonist of the serotonin (5-hydroxytryptamine or 5-HT) receptor 5-HT6 with at least 100-fold selective for 5-HT6 (pKi = 9.02-8.92) over. Synonyms: 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-benzo[b]thiophene-2-sulfonamide Hydrochloride; SB 271046A. CAS No. 209481-24-3. Molecular formula: C20H23Cl2N3O3S2. Mole weight: 488.45. | |
SB273005 Quick inquiry Where to buy Suppliers range | SB273005 inhibits human osteoclast-mediated bone resorption with IC50 of 11 nM.SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively. Synonyms: SB 273005; SB-273005; (S)-2-(8-(2-(6-(Methylamino)pyridin-2-yl)ethoxy)-3-oxo-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)acetic acid. Grades: >98%. CAS No. 205678-31-5. Molecular formula: C22H24F3N3O4. Mole weight: 451.44. | |
Sb-277011 Quick inquiry Where to buy Suppliers range | Sb-277011 is a novel, high-anity and selective dopamine D3 receptor antagonist that may have potential in treating the negative symptoms of schizophrenia. pKi: 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively. Synonyms: N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide SB 277011 SB 277011-A SB-277011 SB-277011-A trans-N-(4-(2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)cyclohexyl)-4-quinolinecarboxamide. CAS No. 215803-78-4. Molecular formula: C28H30N4O. Mole weight: 438.56. | |
SB 277011A dihydrochloride Quick inquiry Where to buy Suppliers range | SB 277011A dihydrochloride is a selective and brain penetrating dopamine D3 receptor antagonist (pKi = 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B, respectively) with 100-fold selectivity over the hD2 receptor and over 66 other receptors. Synonyms: SB 277011A dihydrochloride; SB277011A dihydrochloride; SB-277011A dihydrochloride; N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1226917-67-4. Molecular formula: C28H30N4O.2HCl. Mole weight: 511.49. | |
SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A) Quick inquiry Where to buy Suppliers range | A brain-penetrant, high-affinity, and selective dopamine D3 receptor antagonist. High affinity for the hD3 receptor (pKi = 7.95) with 100-fold selectivity over the hD2 receptor and over 66 other receptors, enzymes, and ion channels. Rat data shows that the compound is selective for the D3 receptor over certain serotonergic and cholinergic receptors at doses up to 56mg/kg and strong physiological response at 32mg/kg. Group: Biochemicals. Grades: Highly Purified. CAS No. 1226917-67-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
SB-277011-A hydrochloride hydrate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 215804-67-4 (anhydrous). Pack Sizes: 5MG, 25MG. Mole weight: 475.02 (anhydrous basis). Catalog: ALP215804674. Assay: ≥98% (HPLC). | |
Sb 277011 hydrochloride Quick inquiry Where to buy Suppliers range | Sb 277011 hydrochloride. Group: Main Products. Alternative Names: SB 277011 Hydrochloride;N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- 4-quinolinecarboxaMide Hydrochloride;SB 277011A Hydrochloride;SB 277211 Hydrochloride;SB-277011-A hydrochloride hydrate. Grades: 98%+. CAS No. 215804-67-4. Molecular formula: C28H30N4O. Mole weight: 438.564. IUPAC Name: N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide. SMILES: C1CC (CCC1CCN2CCC3=C (C2)C=CC (=C3)C#N)NC (=O)C4=CC=NC5=CC=CC=C45. InChIKey: OLWRVVHPJFLNPW-UHFFFAOYSA-N. H-Bond Donor: 1. H-Bond Acceptor: 4. | |
SB 277011 hydrochloride Quick inquiry Where to buy Suppliers range | SB 277011 hydrochloride. Group: Biochemicals. Alternative Names: N-[trans-4-[2- (6-Cyano-3, 4-dihydro-2 (1H) -isoquinolinyl) ethyl]cyclohexyl]-4-quinolinecarboxamide hydrochloride; SB 277011A hydrochloride; SB 277211 hydrochloride. Grades: Highly Purified. CAS No. 215804-67-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H31ClN4O. US Biological Life Sciences. | Worldwide |
SB290157 trifluoroacetate Quick inquiry Where to buy Suppliers range | SB290157 trifluoroacetate is selective, high affinity, competitive C3a receptor antagonist (IC50 = 200 nM) suitable for use in animal models of inflammation. Synonyms: SB290157 trifluoroacetate; SB 290157 trifluoroacetate; SB-290157 trifluoroacetate; 5- (diaminomethylideneamino) -2-[[2- (2, 2-diphenylethoxy) acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid; IN1105. CAS No. 1140525-25-2. Molecular formula: C24H29F3N4O6. Mole weight: 526.51. | |
SB290157 trifluoroacetate salt Quick inquiry Where to buy Suppliers range | ≥97% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1140525-25-2. Pack Sizes: 5MG, 25MG. Mole weight: 526.51. Catalog: AP1140525252-B. Assay: ≥97% (HPLC). | |
SB 297006 Quick inquiry Where to buy Suppliers range | SB 297006 is a potent and selective CCR3 antagonist. Synonyms: 2,2',3,3,3',3'-Hexahydroxy-2,2'-biindan-1,1'-dione; Hydrindantin, anhydrous; 5950-69-6; NSC108697; SB 297006; SB297006; SB-297006; EINECS 227-713-1. CAS No. 58816-69-6. Molecular formula: C18H18N2O5. Mole weight: 342.35. | |
SB 297006 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 58816-69-6. Pack Sizes: 5MG, 25MG. Mole weight: 342.35. Catalog: AP58816696. Assay: ≥98% (HPLC); ≥98% (HPLC). | |
SB 297006 Quick inquiry Where to buy Suppliers range | SB 297006. Group: Biochemicals. Grades: Purified. CAS No. 58816-69-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Sb2Te2Se Crystal Quick inquiry Where to buy Suppliers range | Alfa Chemistry produces Sb2Te2Se as part of its comprehensive catalog of 2D materials. We can guide customers in material characterization and selection. Powder and other forms are available upon request. Request a quote above to receive pricing information based on your specifications. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: 2D Topological Insulators. Alternative Names: Antimony telluride selenide. Molecular Weight: 577.68 g/mol. Molecular Formula: Sb2Te2Se. Flash Point: (6N) 99.9999%. | |
Sb2Te3 Thin Film Quick inquiry Where to buy Suppliers range | Alfa Chemistry offers Sb2Te3 films on different substrates. Size and craftsmanship can be customized. Uses: The film produced by our company is deposited by chemical vapor deposition (CVD) on a variety of substrates, such as silicon oxide wafers, optical sapphire wafers and the like. Group: 2D Thin Films. CAS No. 1327-50-0. Flash Point: 99.9999% (6N). | |
Sb2Te Crystal Quick inquiry Where to buy Suppliers range | Alfa Chemistry produces Sb2Te as part of its comprehensive catalog of 2D materials. We can guide customers in material characterization and selection. Powder and other forms are available upon request. Request a quote above to receive pricing information based on your specifications. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: 2D Topological Insulators. Alternative Names: Antimony telluride, antimony ditelluride. Molecular Weight: 371.12 g/mol. Molecular Formula: Sb2Te. Flash Point: (6N) 99.9999%. | |
Sb2TeSe2 Crystal Quick inquiry Where to buy Suppliers range | Alfa Chemistry produces Sb2TeSe2 as part of its comprehensive catalog of 2D materials. We can guide customers in material characterization and selection. Powder and other forms are available upon request. Request a quote above to receive pricing information based on your specifications. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: 2D Topological Insulators. Alternative Names: Antimony telluride selenide. Molecular Weight: 529.04 g/mol. Molecular Formula: Sb2TeSe2. Flash Point: (6N) 99.9999%. | |
SB-311009 Quick inquiry Where to buy Suppliers range | SB-311009 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 311009; SB311009. Molecular formula: C22H36N2O5. Mole weight: 408.5. | |
SB-315021 Quick inquiry Where to buy Suppliers range | SB-315021 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 315021; SB315021. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
SB 328437 Quick inquiry Where to buy Suppliers range | SB 328437 is a potent and selective CCR3 antagonist. Synonyms: methyl 2-naphthoylamino-3-(4-nitrophenyl)propionate; SB328437; SB 328437; SB-328437. CAS No. 247580-43-4. Molecular formula: C21H18N2O5. Mole weight: 378.38. | |
SB 328437 Quick inquiry Where to buy Suppliers range | SB 328437. Group: Biochemicals. Grades: Purified. CAS No. 247580-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
SB-332235 Quick inquiry Where to buy Suppliers range | SB-332235 is a potent CXCR2 antagonist. Synonyms: 6-chloro-3-(3-(2,3-dichlorophenyl)ureido)-2-hydroxybenzenesulfonamide; SB-332235; SB 332235; SB332235. CAS No. 276702-15-9. Molecular formula: C13H10Cl3N3O4S. Mole weight: 410.66. | |
SB 334867 Quick inquiry Where to buy Suppliers range | SB 334867. Group: Biochemicals. Alternative Names: N-(2-Methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-urea Hydrochloride. Grades: Highly Purified. CAS No. 249889-64-3. Pack Sizes: 10mg. Molecular Formula: C17H14ClN5O2, Molecular Weight: 355.78. US Biological Life Sciences. | Worldwide |
SB-334867 Quick inquiry Where to buy Suppliers range | SB-334867, with sedative and anorectic effects, it is the first non-peptide selective antagonist of orexin receptor subtype OX1 (pKb= 7.2) with 50 -fold selectivity for OX1 over OX2 receptors. in vitro: inhibited the orexin-A (10 nM) and orexin-B (100 nM). Synonyms: 1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea hydrochloride SB 334867-A SB 334867A SB-334867 SB-334867-A SB-334867A SB3348. Grades: >99 %. CAS No. 249889-64-3. Molecular formula: C17H13N5O2. Mole weight: 319.32. | |
SB-366791 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 472981-92-3. Pack Sizes: 5MG, 25MG. Mole weight: 287.74. Catalog: AP472981923. Assay: ≥98% (HPLC). | |
SB-366791 Quick inquiry Where to buy Suppliers range | SB-366791 is a potent, and selective cinnamide TRPV1 antagonist (pA2 = 7.71 at hVR1) with IC50 of 5.7±1.2 nM. Uses: A potent, and selective cinnamide trpv1 antagonist. Synonyms: SB-366791; SB 366791; SB366791. N-(4-Methoxyphenyl)-4-chlorocinnamamide;3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide. Grades: ≥98%. CAS No. 472981-92-3. Molecular formula: C16H14ClNO2. Mole weight: 287.74. | |
SB366791 (N-(3-Methoxyphenyl)-4-chlorocinnamide) Quick inquiry Where to buy Suppliers range | Potent and selective TRPV1 antagonist. Glutamatergic synaptic transmission inhibitor. Group: Biochemicals. Alternative Names: N-(3-Methoxyphenyl)-4-chlorocinnamide. Grades: Highly Purified. CAS No. 472981-92-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H14ClNO2, Molecular Weight: 287.8. US Biological Life Sciences. | Worldwide |
SB 399885 hydrochloride Quick inquiry Where to buy Suppliers range | SB 399885 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 402713-81-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
SB 399885 hydrochloride Quick inquiry Where to buy Suppliers range | SB 399885 hydrochloride is a brain penetrating and orally active 5-HT6 antagonist, displaying > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi = 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors, respectively). Synonyms: SB 399885 hydrochloride; SB399885 hydrochloride; SB-399885 hydrochloride; N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 402713-81-9. Molecular formula: C18H21Cl2N3O4S.HCl. Mole weight: 482.81. | |
SB-399885 hydrochloride Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 402713-81-9. Pack Sizes: 5MG, 25MG. Mole weight: 482.81. Catalog: AP402713819. Assay: ≥98% (HPLC). | |
SB 399885 Hydrochloride (5-HT6 Receptor Antagonist, SB 399885) Quick inquiry Where to buy Suppliers range | A high affinity 5-HT6 Receptor antagonist (pKi = 9.0). Good solubility (to 100mM in water or DMSO), oral availability, and penetrant to blood brain barrier. Over 200-fold selective for 5-HT6 receptors vs all receptors, ion channels and enzymes tested in Hirst et al. 2006 publication. Shows nootropic, antidepressant and axiolytic effects comparable to well-described drugs such as diazepam, and therefore has been proposed as novel treatment for schizoprenia and Alzheimers disease. Group: Biochemicals. Alternative Names: N- (3, 5-Dichloro-2-methoxyphenyl) -4-methoxy-3- (1-piperazinyl) benzenesulfonamide Hydrochloride; SB 399885 Monohydrochloride. Grades: Highly Purified. CAS No. 402713-80-8. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
SB 3CT Quick inquiry Where to buy Suppliers range | SB 3CT. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS003005. Format: Neat. | |
SB-3CT Quick inquiry Where to buy Suppliers range | SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. Besides, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. Synonyms: MMP-2/MMP-9 Inhibitor IV; 2- ( (4-phenoxyphenylsulfonyl) methyl) thiirane; SB-3CT; SB3CT; SB3-CT; IN1250; IN 1250; IN-1250. Grades: 98%. CAS No. 292605-14-2. Molecular formula: C15H14O3S2. Mole weight: 306.394. | |
SB 4 Quick inquiry Where to buy Suppliers range | SB 4 is a potent and selective BMP4 signaling agonist with EC50 value of 74 nM. It enhances canonical BMP signaling and activates SMAD-1/5/9 phosphorylation. Synonyms: 2-[[(4-Bromophenyl)methyl]thio]benzoxazole. Grades: ≥99% by HPLC. CAS No. 100874-08-6. Molecular formula: C14H10BrNOS. Mole weight: 320.2. | |
SB408124 Quick inquiry Where to buy Suppliers range | SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor. Synonyms: SB-408124; SB 408124; SB408124. Grades: >98%. CAS No. 288150-92-5. Molecular formula: C19H18F2N4O. Mole weight: 356.37. | |
SB-408124 (Hydrochloride) Quick inquiry Where to buy Suppliers range | SB-408124 (Hydrochloride) is the hydrochloride salt form of SB-408124. SB-408124 is a selective antagonist of OX1 (for human OX1 Kb= 21.7nM; for human OX2 Kb=1405nM). In vivo: after oral administration it moderates Orexin-A blocking the vasopressin (VP) l. Synonyms: 1-(6, 8-difluoro-2-methylquinolin-4-yl)-3-[4-(dimethylamino)phenyl]urea; hydrochlorideSB-408124 (Hydrochloride)1431697-90-3C19H18F2N4O.ClH3024AHCS-1073; HY-76612; W-5807; SB-408124 (Hydrochloride); CS 1073; HY 76612; W 5807; SB 408124 (Hydrochloride); CS1073; HY76612; W5807; SB408124 (Hydrochloride);1-(6,8-Difluoro-2-methylquinolin-4-yl)-3-(4-(dimethylamino)phenyl)urea hydrochloride. CAS No. 1431697-90-3. Molecular formula: C19H19ClF2N4O. Mole weight: 392.84. | |
SB415286 Quick inquiry Where to buy Suppliers range | SB415286 is a potent GSK3α inhibitor with IC50 and Ki values of 78 nM and 31 nM,respectively. Synonyms: SB-415286; SB 415286; SB415286. Grades: >98%. CAS No. 264218-23-7. Molecular formula: C16H10ClN3O5. Mole weight: 359.72. | |
SB-423562 Quick inquiry Where to buy Suppliers range | SB-423562 is a short-acting calcium sensitive receptor (CaR) antagonist. Synonyms: UNII-615K7YBS59. Grades: 98%. CAS No. 351490-27-2. Molecular formula: C26H32N2O4. Mole weight: 436.5. | |
SB 431542 Quick inquiry Where to buy Suppliers range | SB 431542 is a potent and selective inhibitor of the TGF- β1 receptor ALK5 (IC50 = 94 nM)1. It inhibits ALK4 only at higher concentrations (IC50 = 140nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM)2 and ALK7.3 It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested.3 SB 431542 specifically blocks Smad signaling, reducing gene expression relevant to fibrosis and cancer.3 Through its effects on ALK/Smad signaling, SB 431542 suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.4,5. Group: Biochemicals. Alternative Names: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide. Grades: Highly Purified. CAS No. 301836-41-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
SB-431542 Quick inquiry Where to buy Suppliers range | SB-431542 Inhibitor. Uses: Scientific use. Product Category: T1726. CAS No. 301836-41-9. | |
SB431542 Quick inquiry Where to buy Suppliers range | SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. Uses: Reprogramming, differentiation. Synonyms: SB431542; SB-431542; SB 431542. Grades: 98%. CAS No. 301836-41-9. Molecular formula: C22H16N4O3. Mole weight: 384.39. | |
SB 431542 hydrate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 301836-41-9 (anhydrous). Pack Sizes: 5MG. Mole weight: 384.39 (anhydrous basis). Catalog: ALP301836419. Assay: ≥98% (HPLC). | |
SB 452533 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 459429-39-1. Pack Sizes: 5MG, 25MG. Mole weight: 376.29. Catalog: AP459429391. Assay: ≥98% (HPLC). | |
SB 452533 Quick inquiry Where to buy Suppliers range | SB 452533 is a potent and selective TRPV1 antagonist against capsaicin (pKb = 7.7), noxious heat and acid-mediated (pIC50 = 7.0) receptor activation (pKi = 6.22 at the recombinant hTRPV1 receptor). Synonyms: SB452533; SB 452533; SB-452533. N-(2-Bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]ethyl]-urea; 1-(2-bromophenyl)-3-[2-(N-ethyl-3-methylanilino)ethyl]urea. Grades: ≥98% by HPLC. CAS No. 459429-39-1. Molecular formula: C18H22BrN3O. Mole weight: 376.29. | |
SB 505124 Quick inquiry Where to buy Suppliers range | SB 505124. Group: Biochemicals. Grades: Purified. CAS No. 694433-59-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
SB-505124 Quick inquiry Where to buy Suppliers range | SB-505124 Inhibitor. Uses: Scientific use. Product Category: T2462. CAS No. 694433-59-5. | |
SB505124 Quick inquiry Where to buy Suppliers range | SB505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5, ALK4 and ALK7) with potential anticancer activity. SB505124 selectively inhibits signaling from TGF-β and activin but does not inhibit other ALK family members. Synonyms: SB-505124; 2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine. Grades: >98%. CAS No. 694433-59-5. Molecular formula: C20H21N3O2. Mole weight: 335.407. | |
SB-505124 hydrochloride Quick inquiry Where to buy Suppliers range | SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less potency. SB-505124 blocks TGF-β-induced apoptosis of FaO cells and NRP 154 cells in a concentration-dependent manner. SB-505124 has been shown to suppress the migration and invasion of breast cancer MCF-7-M5 cells. Synonyms: SB 505124 hydrochloride; SB505124 hydrochloride; SB505124 HCl; SB 505124 HCl; SB-505124 HCl. Grades: >98%. CAS No. 356559-13-2. Molecular formula: C20H22ClN3O2. Mole weight: 371.86. | |
SB-505124 hydrochloride hydrate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 694433-59-5 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 335.40 (anhydrous free base basis). Catalog: ALP694433595. Assay: ≥98% (HPLC). |