A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
S(-)-Baclofen Hydrochloride is the salt of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Synonyms: l-Baclofenhydrochloride; (S)-4-Amino-3-(4-chlorophenyl)butyric Acid Hydrochloride; (-)-Baclofen Hydrochloride; β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride; (S)-β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride; (βS)-β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride. CAS No. 63701-56-4. Molecular formula: C10H13Cl2NO2. Mole weight: 250.12.
sBADA
sBADA is a potent green fluorescent dye. sBADA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA is used to label peptidoglycans in bacterial cell walls in situ. (λ ex =490 nm, λ em =510 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2376838-11-6. Pack Sizes: 1 mg. Product ID: HY-D1690A.
S(-)-BAY K 8644
S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the enantiomer of (±)-Bay K 8644. It increased whole-cell Ca2+ currents in A7r5 smooth muscle cells but effectively blocked further stimulatio. It enhanced transcoronary exchange more markedly than (+/-)-Bay W 5035 or (+/-)-Bay T 5006, reflecting the differences in coronary constrictor activity. It demonstrates vasoconstrictive and positive inotropic effects in vivo as well as behavioral effects, including deficits to motor function. It can enable reprogramming of mouse embryonic fibroblasts after transduction with Oct4/Klf when combined with BIX01294. Uses: S(-)-bay k 8644 has positive inotropic, vasoconstrictive and behavioral effects. Synonyms: Methyl (4S)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate;Bay-K-8644 (S)-(-)-;(S)-(-)-Bay-K-8644;(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester;S-(-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester;[4S,(-)]-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid methyl ester. Grades: >99 %. CAS No. 98625-26-4. Molecular formula: C16H15F3N2O4. Mole weight: 356.30.
Sbc-1107326
SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). Study shows that it can lower cholesterol levels in mice. Synonyms: Sbc 1107326; Sbc1107326; N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide. Grades: ≥98%. CAS No. 1629166-02-4. Molecular formula: C26H27N3O2. Mole weight: 413.51.
SBC-115076
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Synonyms: SBC-115076; SBC 115076; SBC115076. Grades: 98%. CAS No. 489415-96-5. Molecular formula: C31H33N3O5. Mole weight: 527.62.
SBD-1 is an antibacterial peptide isolated from Ov is aries. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Beta-defensin 1; BD-1; Asn-Arg-Leu-Ser-Cys-His-Arg-Asn-Lys-Gly-Val-Cys-Val-Pro-Ser-Arg-Cys-Pro-Arg-His-Met-Arg-Gln-Ile-Gly-Thr-Cys-Arg-Gly-Pro-Pro-Val-Lys-Cys-Cys-Arg-Lys-Lys. Molecular formula: C195H342N78O50S7. Mole weight: 4803.77.
SBD-F
SBD-F. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Fluorobenzofurazan-4-sulfonicacid ammonium salt. Product Category: Other Fluorophores. Appearance: Yellow powder. CAS No. 84806-27-9. Molecular formula: C6H6FN3O4S. Mole weight: 235.19. Purity: 98%+. IUPACName: Azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonicacid. Canonical SMILES: C1=C(C2=NON=C2C(=C1)S(=O)(=O)O)F.N. Product ID: ACM84806279-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: SBD Freeway.
SBE13
SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. Its IC50 value is 0.2 nM. It does not effect the activity of Plk2, Plk3 and Aurora A kinases. It may be used in cell signaling studies. Uses: Sbe13 may be used in cell signaling studies. Synonyms: SBE13; SBE 13; SBE-13; STK510569;N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methyl]-2-(3,4-dimethoxyphenyl)ethanamine. Grades: >98%. CAS No. 775294-82-1. Molecular formula: C24H27ClN2O4. Mole weight: 442.94.
SBE-13 HCl
SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. SBE13 does not effect the activity of Plk2, Plk3, Aurora A kinases. Synonyms: SBE 13 HCl; SBE13 HCl. Grades: 0.98. CAS No. 1052532-15-6. Molecular formula: C24H28Cl2N2O4. Mole weight: 479.398.
SBE-13 HCl
SBE-13 is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μ M for PLK1, PLK3 and PLK2 respectively). Uses: Designed for use in research and industrial production. Additional or Alternative Names: SBE13; SBE 13; SBE13; SBE-13 HCl. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 1052532-15-6. Molecular formula: C24H27ClN2O4. Mole weight: 442.94. Purity: >98%. IUPACName: N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride. Canonical SMILES: COC1=CC=C(CCNCC2=CC=C(OCC3=CC=C(Cl)N=C3)C(OC)=C2)C=C1OC.[H]Cl. Product ID: ACM1052532156. Alfa Chemistry ISO 9001:2015 Certified. Categories: SBE13 hydrochloride.
SBE-β-CD, also called as Sulfobutylether beta-cyclodextrin sodium, is a β-Cyclodextrin derivative with sulfobutyl ether groups and sodium ions substituted designed to optimize the drug properties. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation. Synonyms: SBE4-b-CyD; SBECD; Betadex Sulfobutyl Ether Sodium; Sulfobutyl Ether Beta-Cyclodextrin; Sulfobutyl Ether-Beta-Cyclodextrin; Sodium Sulphobutylether-Beta-Cyclodextrin. Grades: 95%. CAS No. 182410-00-0. Molecular formula: C70H119Na7O56S7. Mole weight: 2242.05.
S-Benzyl-DL-cysteine-2,3,3-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-3-benzylsulfanyl-2,3,3-trideuteriopropanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 51494-04-3. Molecular formula: C10H10D3NO2S. Mole weight: 214.3. Purity: 98 atom % D. IUPACName: 2-amino-3-benzylsulfanyl-2,3,3-trideuteriopropanoic acid. Canonical SMILES: [2H]C([2H])(C([2H])(C(=O)O)N)SCC1=CC=CC=C1. Product ID: ACM51494043. Alfa Chemistry ISO 9001:2015 Certified.
S-Benzyl-D-penicillamine
S-Benzyl-D-penicillamine. Group: Biochemicals. Alternative Names: D-Pen(Bzl)-OH; H-b,b-Dimethyl-D-Cys(Bzl)-OH. Grades: Highly Purified. CAS No. 54536-38-8. Pack Sizes: 500mg, 1g, 2g. US Biological Life Sciences.
Worldwide
S-Benzyl-D-penicillamine 99+% (HPLC)
S-Benzyl-D-penicillamine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 2.5g. US Biological Life Sciences.
Worldwide
S-Benzyl-L-cysteine
S-Benzyl-L-cysteine. Group: Biochemicals. Alternative Names: L-Cys(Bzl)-OH; (R)-2-Amino-3-benzylsulfanyl-propionic acid. Grades: Highly Purified. CAS No. 3054-1-1. Pack Sizes: 100g, 250g. US Biological Life Sciences.
An interesting synthetic intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
s-Benzyl-L-cysteinol
s-Benzyl-L-cysteinol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Benzyl-L-cysteinol, 85803-43-6, (R)-2-Amino-3-(benzylthio)-1-propanol, H-Cysteinol(Bzl), AmbotzHAL1045, AC1Q4UB9, SureCN1168400, 345253_ALDRICH, CTK2I3934, MolPort-001-794-247, AKOS016010519, (R)-2-Amino-3-(benzylthio)propan-1-ol, AK117105, KB-60406, (2R)-2-Amino-3-(Benzylsulfanyl)Propan-1-Ol, 1-Propanol, 2-amino-3-[(phenylmethyl)thio]-, (2R)-. Product Category: Heterocyclic Organic Compound. CAS No. 85803-43-6. Molecular formula: C10H15NOS. Mole weight: 197.3. Purity: 0.96. IUPACName: (2R)-2-amino-3-benzylsulfanylpropan-1-ol. Canonical SMILES: C1=CC=C(C=C1)CSCC(CO)N. Density: 1.155g/cm³. Product ID: ACM85803436. Alfa Chemistry ISO 9001:2015 Certified.
S-benzyl-L-cysteinol
S-benzyl-L-cysteinol. Group: Biochemicals. Alternative Names: L-Cysteinol(Bzl); H-L-Cys(Bzl)-ol. Grades: Highly Purified. CAS No. 85803-43-6. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
S-benzyl-L-cysteinol 99.5+% (HPLC)
S-benzyl-L-cysteinol 99.5+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 85803-43-6. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
S-Benzyl-L-homocysteine
Intermediate in the preparation of L-(+)-Cystathionine. Group: Biochemicals. Alternative Names: L-2-Amino-4-(benzylthio)butyric Acid; S-(Phenylmethyl)-L-homocysteine;2-Amino-4-benzylthiobutyric Acid; NSC 164657; NSC 206263. Grades: Highly Purified. CAS No. 7689-60-3. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
s-Benzyl-N-boc-ethanethiolamine
s-Benzyl-N-boc-ethanethiolamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[2-[(Phenylmethyl)thio]ethyl]carbamic Acid 1,1-Dimethylethyl Ester. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Oil. CAS No. 873330-01-9. Molecular formula: C14H21NO2S. Mole weight: 267.39. Purity: 0.96. IUPACName: tert-butyl N-(2-benzylsulfanylethyl)carbamate. Density: 1.079g/cm³. Product ID: ACM873330019. Alfa Chemistry ISO 9001:2015 Certified.
S-Benzyl-N-Boc-ethanethiolamine
S-Benzyl-N-Boc-ethanethiolamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
S-Benzyl-N-Stearoyl-L-cysteine
S-Benzyl-N-Stearoyl-L-cysteine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
S-Benzylthioacetimidate, Hydrochloride
S-Benzylthioacetimidate, Hydrochloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
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Sbf I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and of these more than 90% canrecut. Group: Restriction Enzymes. Purity: 200U; 1000U. CCTGCA↑GG GG↓ACGTCC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sbf I gene from Streptomyces species Bf61. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1170RE.
SBFI-AM
SBFI-AM is a Na + selective fluorescent indicator. SBFI-AM shows selectivity for Na + over K + [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 129423-53-6. Pack Sizes: 281 μg (5 mM * 50 μL in DMSO). Product ID: HY-126831.
SBHA
SBHA. Group: Biochemicals. Grades: Purified. CAS No. 38937-66-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
SBHA - CAS 38937-66-5
A cell-permeable bishydroxamic acid histone deacetylase (HDAC) inhibitor with anti-tumor properties. Group: Fluorescence/luminescence spectroscopy.
SBHA (Suberohydroxamic acid, Suberic bis-hydroxamic acid, N, N'-dihydroxyoctane diamide)
SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50=0.25uM) and HDAC3 (IC50=0.30uM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 38937-66-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
SBI-0206965 is a novel selective inhibitor of the autophagy-initiating kinase ULK1 (IC50 = 108 nM) that is less effective against ULK2 (IC50 = 711 nM). SBI0206965 promoted apoptosis in NSCLC cells independent of autophagy, which was partly mediated by destabilization of Bcl2/Bclxl. Synonyms: 2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide; SBI-0206965; SBI 0206965; NSC-784816; Benzamide, 2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl-; 2-({5-Bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl}oxy)-N-methylbenzamide. Grades: 98%. CAS No. 1884220-36-3. Molecular formula: C21H21BrN4O5. Mole weight: 489.33.
SBI-0206965
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50s of 108 nM for ULK1 kinase and 711 nM for the highly related kinase ULK2. SBI-0206965 is also an AMPK inhibitor that can paradoxically increase Thr172 phosphorylation[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1884220-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16966.
SBI-0640756 (SBI-756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBI-756. CAS No. 1821280-29-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19560.
SBI-115
SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 882366-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111534.
SBI-425
SBI-425 is an orally active and potent TNAP (tissue-nonspecific alkaline phosphatase) inhibitor (IC50=16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1451272-71-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124756.
SBI-477
SBI-477 is a small-molecule probe that can stimulate insulin signaling by deactivating the transcription factor MondoA, causing reduction of expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). It coordinately inhibited triacylglyceride (TAG) synthesis and enhanced basal glucose uptake in human skeletal myocytes in study. Uses: Probe. Synonyms: SBI 477; SBI477. CAS No. 781628-99-7. Molecular formula: C24H25N3O6S. Mole weight: 483.54.
SBI-553
SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 ?M[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1849603-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125880.
SBI-581
SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor, with an IC50 of 42 nM. SBI-581 promotes TKS5? accumulation at RAB11-positive vesicles. SBI-581 inhibits invadopodia formation. SBI-581 shows reasonable pharmacokinetics in mice using IP injection. SBI-581 shows antitumor activity[1]. SBI-581 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139439.
SBI-797812
SBI-797812 is an orally active nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD+. SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD+ in mice[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2237268-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126255.