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| Product | Description | |
|---|---|---|
| SCH-202676 hydrobromide | SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors ( GPCRs ) and adenosine receptor ( AR ). SCH-202676 hydrobromide has antiviral activity and inhibits 3CL pro in a time-dependent manner with an IC 50 value of 0.655 μM [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 265980-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110012. |  |
| SCH-202676 hydrobromide | 98%. Group: Fluorescence/luminescence spectroscopy. |  |
| Sch-20561 | Sch-20561 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Synonyms: Sch 20561. Molecular formula: C57H86N12O16. Mole weight: 1195.4. |  |
| Sch-20562 | Sch-20562 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Synonyms: Sch 20562. Molecular formula: C63H96N12O21. Mole weight: 1357.5. | |
| Sch 218157 | Sch 218157 is a cyclodepsipeptide isolated from an unidentified fungus MYCO-2833. It selectively binds to NK2 receptor with IC50 of 68 nmol/L. Synonyms: Sch-218157. Molecular formula: C57H89N11O13. Mole weight: 1136.4. | |
| SCH 221510 | SCH 221510. Group: Biochemicals. Grades: Purified. CAS No. 322473-89-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SCH 221510 | SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC 50 of 12 nM and K i of 0.3 nM. SCH 221510 shows an anxiolytic-like effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 322473-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107722. | |
| SCH 221510 | SCH 221510 is a potent and selective nociceptin opioid receptor (NOP) agonist (EC50 = 12, 693, 683 and 8071 nM, and Ki = 0.3, 65, 131 and 2854 nM at NOP, μ-, κ- and δ-opioid receptors, respectively). SCH 221510 exhibits anxiolytic-like activity at doses that have no effect on overt behaviors such as locomotion in vivo. SCH 221510 is used as the therapy of neuropathic and inflammatory pain. Uses: Potential anti-inflammatory agent. Synonyms: SCH221510; SCH 221510; SCH-221510; 3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol. Grades: ≥99% by HPLC. CAS No. 322473-89-2. Molecular formula: C28H31NO. Mole weight: 397.55. | |
| SCH 23390 hydrochloride | SCH 23390 hydrochloride is the hydrochloride salt of SCH 23390 which is a dopamine receptor antagonist. SCH 23390, a halobenzazepine, is a selective antagonist of the dopamine D1-like receptor subtypes D1 (Kis = 0.2 nM) and D5 (Kis = 0.3 nM). Synonyms: SCH 23390 hydrochloride; SCH-23390 hydrochloride; SCH23390 hydrochloride; (5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride. CAS No. 125941-87-9. Molecular formula: C17H19Cl2NO. Mole weight: 324.24. | |
| SCH 23390 hydrochloride | SCH 23390 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 125941-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-23390 hydrochloride | SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D 1 -like receptor antagonist with K i s of 0.2 nM and 0.3 nM for the D 1 and D 5 receptor , respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT 2C receptor agonist with a K i of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT 2 and 5-HT 1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC 50 of 268 nM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-(+)-SCH-23390 hydrochloride. CAS No. 125941-87-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19545A. | |
| SCH 23390 Hydrochloride (Dopamine Receptor D1/D5 Antagonist, SCH 23390, (R)-(+)-7-Chloro-8-hydroxy-3-methylÂ-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride, SCH23390, SCH-23390) | A highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3nM and 9.3nM respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 125941-87-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClNO HCl. US Biological Life Sciences. | Worldwide |
| SCH 28080 | SCH 28080 is a potent inhibitor of H+/K+-ATPase (IC50 = 20 nM). SCH 28080 binds to the K+ recognition site and is competitive with respect to K+. SCH 28080 blocks gastric acid secretion in vitro and in vivo via inhibiting gastric H+/K+-ATPase. Uses: Anti-ulcer agents. Synonyms: SCH 28080; SCH28080; SCH-28080; 2-Methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile; Schering compound 28080. Grades: ≥99% by HPLC. CAS No. 76081-98-6. Molecular formula: C17H15N3O. Mole weight: 277.33. | |
| SCH 28080 | SCH 28080. Group: Biochemicals. Grades: Purified. CAS No. 76081-98-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-28080 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Sch-31828 | Sch-31828 is a novel antibiotic from a Microbispora sp. SCC 1438. It is commonly used as methyl ether form. Synonyms: Sch 31828; Antibiotic EV22; EV 22. CAS No. 115216-83-6. Molecular formula: C17H18O6. Mole weight: 318.32. | |
| SCH 336 | SCH 336 is a potent and selective CB2 receptor inverse agonist (Ki = 1.8 nM, EC50 = 2 nM) with 100-fold selectivity over CB1. SCH 336 has been shown to increase forskolin stimulated cAMP accumulation in CHO cells expressing human CB2 receptors. It inhibits leukocyte migration in a murine model of delayed-type hypersensitivity and suppresses antigen-induced lung eosinophilia in a mouse allergy model. Synonyms: SCH-336; SCH 336; SCH336. N- [ (1S) -1- [4- [ [4-Methoxy-2- [ (4-methoxyphenyl) sulfonyl] phenyl] sulfonyl] phenyl] ethyl] methanesulfonamide. Grades: ≥98% by HPLC. CAS No. 447459-51-0. Molecular formula: C23H25NO8S3. Mole weight: 539.64. | |
| Sch-37137 | Sch-37137 is a dipeptide antibiotic produced by Micromonospora sp. SCC 1792. It was weakly active against species of Candida and dermatophytes (mean MICs greater than or equal to 128 mg/ml) in Sabouraud dextrose, yeast-nitrogen and modified Eagles minimum essential media; however activity against Candida sp. (mean MICs greater than or equal to 12 mg/ml) and dermatophytes (mean MICs greater than or equal to 0.8 mg/ml) significantly improved in MA medium. Synonyms: Sch 37137; N-L-Alanyl-3- ( ( (3- (aminocarbonyl) oxiranyl) carbonyl) amino) -L-alanine. Grades: 95%. CAS No. 113737-67-0. Molecular formula: C10H16N4O6. Mole weight: 288.26. | |
| Sch-38516 | Sch-38516 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 0.91 μg/mL. Synonyms: Sch 38516. CAS No. 128563-23-5. Molecular formula: C24H46N2O5. Mole weight: 442.6. | |
| Sch-38518 | Sch-38518 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 1.81 μg/mL. Synonyms: Sch 38518. CAS No. 135559-94-3. Molecular formula: C25H48N2O5. Mole weight: 456.7. | |
| Sch-38519 | Sch-38519 is an isochromanequinone structurally related to lactoquinomycin. It is isolated from Thermomonospora sp. SCC 1793. It inhibits thrombin-induced aggregation of human platelets and is active against gram-positive and gram-negative bacteria. Synonyms: Sch 38519; Antibiotic Sch 38519. Grades: >95% by HPLC. CAS No. 114970-20-6. Molecular formula: C24H25NO8. Mole weight: 455.4. | |
| SCH 39166 hydrobromide | SCH 39166 hydrobromide is a high affinity dopamine D1/D5 receptor antagonist (Ki = 1.2, 2, 980, 5520, 80 and 731 nM for binding to D1, D5, D2, D4, 5-HT and α2a receptors, respectively). SCH 39166 is used in the treatment of schizophrenia, cocaine addiction and obesity. Uses: The treatment of schizophrenia, cocaine addiction and obesity. Synonyms: SCH 39166 hydrobromide; SCH39166 hydrobromide; SCH-39166 hydrobromide; (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide; Ecopipam hydrobromide. Grades: ≥99% by HPLC. CAS No. 1227675-51-5. Molecular formula: C19H20ClNO.HBr. Mole weight: 394.73. | |
| SCH 39166 hydrobromide | SCH 39166 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1227675-51-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sch-39185 | Sch-39185 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 2 μg/mL. Synonyms: Sch 39185. CAS No. 135559-95-4. Molecular formula: C25H48N2O5. Mole weight: 456.7. | |
| Sch 40832 | Sch 40832 is an antibiotic produced by Micromonospora carbonacea var africana. It exhibits activity against gram-positive bacteria with MIC of 0.1-1.0 μg/mL. Synonyms: Antibiotic Sch 40832; Sch-40832. Molecular formula: C84H104N18O26S5. Mole weight: 1942.2. | |
| Sch412348 | 412348 is an adenosine A2A receptor antagonist with anti-Parkinsonian activity in both rodent andprimate animal models. Because of its high affinity for the adenosine A2A receptor and pronounced selectivity over the adenosine A1 receptor,SCH 412348 is an excellent tool compound to assess the role of the adenosine A2A receptorinmovement. Uses: Adenosine a2 receptor antagonists. Synonyms: (7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine; SCH 412348; SCH-412348; SCH412348. CAS No. 377727-26-9. Molecular formula: C22H21F2N9O. Mole weight: 465.46. | |
| Sch 420789 | Sch 420789 is a phospholipase D inhibitor produced by an unidentified fungus SCF 0953. Synonyms: Sch-420789. Molecular formula: C27H36O6. Mole weight: 456.6. | |
| Sch 42137 | Sch 42137 is an antifungal antibiotic isolated from Actinoplanes sp. It exhibited MIC values less than 0.125 μg/mL against yeasts and dermatophytes. Synonyms: Antibiotic Sch 42137; Sch-42137. CAS No. 142383-44-6. Molecular formula: C29H27NO10. Mole weight: 549.5. | |
| SCH 442416 | SCH 442416 is a very selective, high affinity A2A antagonist. Synonyms: SCH-442416; SCH 442416; SCH442416. 2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine. CAS No. 316173-57-6. Molecular formula: C20H19N7O2. Mole weight: 389.42. | |
| SCH 442416 | SCH 442416. Group: Biochemicals. Grades: Purified. CAS No. 316173-57-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-442416 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Sch 466457 | Sch 466457 is a peptide active against Candida, dermatophytes and Aspergillus with MIC of 8.9, 20 and 16 microg/mL. Synonyms: Sch-466457. Molecular formula: C80H140N20O20. Mole weight: 1702.08. | |
| Sch 47554 | Sch 47554 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Synonyms: Antibiotic Sch 47554; Sch-47554. CAS No. 150050-20-7. Molecular formula: C37H38O13. Mole weight: 690.7. | |
| Sch 47555 | Sch 47555 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Synonyms: Antibiotic Sch 47555; Sch-47555. CAS No. 150050-21-8. Molecular formula: C37H42O13. Mole weight: 694.7. | |
| Sch 484129 | Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Synonyms: Sch-484129. Molecular formula: C31H54O12. Mole weight: 618.8. | |
| Sch 484130 | Sch 484130 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Synonyms: Sch-484130. Molecular formula: C31H54O12. Mole weight: 618.8. | |
| Sch 50673 | Sch 50673 is an antitumor metabolite produced by Nattrassia mangiferae. Synonyms: Sch-50673. Molecular formula: C21H14O8. Mole weight: 394.3. | |
| Sch 50676 | Sch 50676 is an antitumor metabolite produced by Nattrassia mangiferae. Synonyms: Sch-50676. Molecular formula: C20H14O5. Mole weight: 334.3. | |
| SCH 50911 | SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC 50 of 1.1 μM. SCH 50911 antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3 H overflow with an IC 50 of 3 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 733717-87-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12783A. | |
| SCH-50911 | CH-50911 is a selective GABA-B antagonist with IC50 value of 1.1 μM. It is developed by Schering-Plough Corporation. CH-50911 is often used in pharmacology research and it also acts as an anticonvulsant under normal conditions. Preclinical trials for Absence seizures and Cognition disorders in USA were discontinued. Uses: Absence epilepsy; cognition disorders. Synonyms: SCH-50911; SCH 50911; SCH50911; (S)-2-(5,5-dimethylmorpholin-2-yl)acetic acid. Grades: 98%. CAS No. 733717-87-8. Molecular formula: C8H15NO3. Mole weight: 173.21. | |
| SCH 51344 | SCH 51344. Group: Biochemicals. Grades: Purified. CAS No. 171927-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-51344 | SCH-51344, a pyrazoloquinolin derivative, has been found to be a MTH1 inhibitor that could be significant in anticancer studies through restraining Ras-induced malignant transformation. Kd = 49 nM. Synonyms: SCH-51344; SCH 51344; SCH51344. Ras/Rac Transformation Blocker, SCH 51344; SCH-51344; 6-Methoxy-4-(2-((2-hydroxyethoxyl)-ethyl)amino)-3-methyl-1H-pyrazolo[3,4-b]quinoline; 2-(2-((6-Methoxy-3-methyl-1H-pyrazolo[3,4-b]quinolin-4-yl)amino)ethoxy)ethanol; 2-{2-[(6-methoxy-3-methyl-1H-pyrazo. Grades: 98%. CAS No. 171927-40-5. Molecular formula: C16H20N4O3. Mole weight: 316.36. | |
| SCH 527123 | A potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively. Synonyms: 2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide; SCH527123; SCH-527123; SCH 527123; MK-7123; MK7123; MK 7123; PS291822; PS-291822; PS 291822; Navarixin monohydrate; Navarixin. CAS No. 473727-83-2. Molecular formula: C21H23N3O5. Mole weight: 397.42. | |
| Sch 528647 | Sch 528647 is an antitumor antibiotic produced by Aspergillus fumigatus. Synonyms: Sch-528647. Molecular formula: C26H34O6. Mole weight: 442.5. | |
| Sch 52900 | Sch 52900 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Synonyms: Sch-52900. Molecular formula: C31H30N6O7S4. Mole weight: 726.9. | |
| Sch 52901 | Sch 52901 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Synonyms: Sch-52901. Molecular formula: C31H30N6O6S4. Mole weight: 710.9. | |
| SCH 529074 | SCH 529074. Group: Biochemicals. Grades: Purified. CAS No. 922150-11-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 529074 | SCH 529074 is a small molecule activator of mutant p53 that binds p53 DNA binding domain (Kd = 1-2 μM) and restores wild-type function to many oncogenic mutants by acting as a chaperone. SCH 529074 blocks ubiquitination of p53 by HDM2, and induces apoptosis in tumor cell lines. Synonyms: SCH 529074; SCH529074; SCH-529074; N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine. Grades: ≥98% by HPLC. CAS No. 922150-11-6. Molecular formula: C31H36Cl2N6. Mole weight: 563.56. | |
| SCH 546738 | SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist with Ki of 0.4 nM. Synonyms: SCH546738; SCH 546738; SCH-546738; 3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide. CAS No. 906805-42-3. Molecular formula: C23H31Cl2N7O. Mole weight: 492.44. | |
| SCH 563705 | SCH 563705 is a potent dual CXCR2/CXCR1 antagonist with IC50 of 1.3 and 7.3 nM, respectively. Synonyms: SCH-563705; SCH 563705; SCH563705. 3-[[3,4-dioxo-2-[[(1R)-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide. CAS No. 473728-58-4. Molecular formula: C23H27N3O5. Mole weight: 425.48. | |
| Sch 56396 | Sch 56396 is a c-fos proto-oncogene inhibitor produced by the fungus Tolypocladium sp. Synonyms: Sch-56396. Molecular formula: C17H20N2O3S. Mole weight: 332.4. | |
| Sch 57404 | Sch 57404 is an antifungal antibiotic produced by an unidentified fungus SCF1082A. Synonyms: Sch-57404. Molecular formula: C27H36O9. Mole weight: 504.6. | |
| Sch 575867 | Sch 575867 is an antifungal antibiotic isolated from a deep-water marine sponge Astroscleridae. It is effective against brewer's yeast with MIC of 15 μg/mL. Synonyms: Sch-575867. Molecular formula: C32H51Na3O13S3. Mole weight: 808.9. | |
| Sch 58053 | An analog of Ezetimibe. SCH 58053 is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine. Group: Biochemicals. Grades: Highly Purified. CAS No. 194423-53-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Sch 58053-d4 | A labeled analog of Ezetimibe. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SCH 58261 | SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC 50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160098-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19533. | |
| SCH 58261 | SCH 58261 is a potent and selective antagonist of adenosine A2A receptor, displaying neuroprotective activity. Uses: Adenosine a2 receptor antagonists. Synonyms: SCH-58261; SCH 58261; SCH58261. 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine. Grades: 98%. CAS No. 160098-96-4. Molecular formula: C18H15N7O. Mole weight: 345.366. | |
| SCH 58261 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SCH 58261 | SCH 58261. Group: Biochemicals. Grades: Purified. CAS No. 160098-96-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sch59498 | Sch59498 is a potent inhibitor of phosphodiesterase 1c (Pde1c) with antihypertensive and antiplatelet effect. Synonyms: Sch59498; Sch 59498; Sch-59498; 2-hexyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclopenta[4,5]imidazo[2,1-b]purin-4-one; 2-Hexyl-5-methyl-7,8-propano-1,4,7beta,8beta-tetrahydro-5H-imidazo[2,1-b]purine-4-one; (6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methylcyclopent[4,5]imidazo[2,1-b]purin-4(3H)-one; DYIUKMSMAJWWAT-NEPJUHHUSA-N. CAS No. 224157-99-7. Molecular formula: C17H25N5O. Mole weight: 315.41. | |
| Sch 599473 | Sch 599473 is a sesterterpene isolated from from a marine sponge, Ircinia sp. It inhibits CCR7 receptor with IC50 of 33 μg/mL. Synonyms: Sch-599473. Molecular formula: C25H40O5S. Mole weight: 452.6. | |
| Sch 725674 | It is a macrocyclic lactone structurally related to gloeosporone. It is a self-germination inhibitor produced by colletotrichum gloeosporioides. It exhibits moderate antifungal activity. Synonyms: Antibiotic Sch 725674; (3E,5R,6S,8R,14R)-5,6,8-Trihydroxy-14-pentyloxacyclotetradec-3-en-2-one; Sch-725674; 5R,6S,8R-trihydroxy-14R-pentyl-oxacyclotetradec-3E-en-2-one. Grades: >95% by HPLC. CAS No. 877061-66-0. Molecular formula: C18H32O5. Mole weight: 328.44. | |
| SCH772984 | SCH772984 is a potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild-type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non-BRAF mutant melanoma or in BRAF-mutant melanoma with innate or acquired resistance, alone or in combination with BRAF inhibitors. Synonyms: SCH-772984; SCH 772984; (R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide. Grades: 95%. CAS No. 942183-80-4. Molecular formula: C33H33N9O2. Mole weight: 587.688. | |
| SCH772984 | SCH772984 Inhibitor. Uses: Scientific use. Product Category: T6066. CAS No. 942183-80-4. |  |
| SCH79797 | SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC 50 of 70 nM and a K i of 35 nM. SCH79797 inhibits thrombin-induced platelet aggregation with an IC 50 of 3 μM. SCH79797 has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 245520-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14993. | |
| SCH 79797 dihydrochloride | SCH 79797 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216720-69-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 79797 dihydrochloride | SCH 79797 dihydrochloride is a potent and selective non-peptide PAR1 receptor antagonist (IC50 = 70 nM). SCH 79797 blocks haTRAP-induced human platelet aggregation. It also inhibits PAR1 agonist- or thrombin-induced increases in cytosolic Ca2+ in vascular smooth muscle cells. Synonyms: SCH79797 dihydrochloride; SCH-79797 dihydrochloride; N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride; 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-, hydrochloride (1:2); N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Hydrochloride (1:2). Grades: ≥99% by HPLC. CAS No. 1216720-69-2. Molecular formula: C23H25N5.2HCl. Mole weight: 444.41. | |
| SCH79797 dihydrochloride | SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC 50 of 70 nM and a K i of 35 nM. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC 50 of 3 μM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216720-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14994. | |
| SCH-900271 | SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC 50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA). SCH-900271 has an improved therapeutic window to flushing [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 915210-50-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-111143. | |
| SCH900776 | SCH900776, also known as MK-8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA-damaging effects of ionizing radiation and alkylating chemotherapeutic agents. Chk1 is an ATP-dependent serine-threonine kinase that in response to DNA damage phosphorylates cdc25 phosphatases, resulting in inhibitory tyrosine phosphorylation of CDK-cyclin complexes and cell cycle arrest. Synonyms: SCH-900776; SCH 900776, MK-8776; MK 8776; MK8776. Grades: >98%. CAS No. 891494-63-6. Molecular formula: C15H18BrN7. Mole weight: 376.262. | |
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